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La Crosse

$471+ Cheap flights from Spartanburg, SC to La Crosse (LSE)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/27. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — LSE
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Spartanburg to La Crosse

Cheapest flights from Spartanburg to La Crosse
Explore the most affordable flight options available from Spartanburg to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:26 pm
CLT
-
LSE
1 stop6h 10m
American Airlines
Tue 3/39:54 am
LSE
-
CLT
1 stop5h 48m
American Airlines
Deal found 1/27$471

Find flight deals from Spartanburg to La Crosse

Keep the following information in mind while searching for Spartanburg to La Crosse flight deals. Data was last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$471
(American Airlines)
Provider with most accurate pricing for Charlotte Douglas-La Crosse flight deals.
Search Deals
Provider most trusted by Cheapflights users for Charlotte Douglas-La Crosse flights.
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From Spartanburg to La Crosse
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Spartanburg to La Crosse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Spartanburg to La Crosse that are best for you.

Fly from

Spartanburg

Fly to

La Crosse

Route

Depart

Return

Price

CharlotteLa Crosse

CLT - LSE

CLTLSE

Charlotte Douglas

Fri 2/27

6:26 pm-11:36 pm

1 stop6h 10m

La Crosse

Tue 3/3

9:54 am-4:42 pm

1 stop5h 48m

$471

CharlotteLa Crosse

CLT - LSE

CLTLSE

Charlotte Douglas

Fri 4/17

11:10 am-6:02 pm

2 stops7h 52m

$601

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Best time to book a flight from Spartanburg to La Crosse

Have a flexible travel schedule? Discover the best time to fly to La Crosse from Spartanburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Spartanburg to La Crosse

What is the cheapest month to book a flight from Spartanburg to La Crosse?

Currently, April is the cheapest month in which you can book a flight from Spartanburg to La Crosse (average of $266). Flying from Spartanburg to La Crosse in December is currently the most expensive (average of $1,194). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing La Crosse

Get insights into the airlines that provide service to La Crosse. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to La Crosse. Reviews last updated January 29, 2026.
Get a feel of what it's like to fly with American Airlines from Spartanburg to La Crosse by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,206 reviews

Boarding

7.5

Comfort

7.2

Crew

8.0

Entertainment

6.9

Overall

7.2

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
American Airlines
7.2
Good
11,206 reviews
American Airlines
7.2
Good
11,206 reviews

Boarding

7.5

Comfort

7.2

Crew

8.0

Entertainment

6.9

Overall

7.2

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from Spartanburg to La Crosse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to La Crosse from Spartanburg?

    Most people fly into La Crosse (LSE) if they book a flight to La Crosse from Spartanburg. On average, La Crosse has 0 inbound flights from Spartanburg per day from 1 airline. La Crosse is conveniently located just 5.4 mi from La Crosse’s city center.

  • How long is the flight from Spartanburg to La Crosse?

    For as low as $471, American Airlines can have you in La Crosse from Spartanburg in 6h 10m. Spartanburg and La Crosse are separated by a distance of 810 mi.

  • Can I find deals for flights from Spartanburg to La Crosse that include hotel bookings?

    Yes. In addition to deals on Spartanburg to La Crosse flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Spartanburg to La Crosse?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Spartanburg to La Crosse.

  • Can I find deals for business class flights from Spartanburg to La Crosse?

    Yes. Cheapflights offers flight deals from Spartanburg to La Crosse by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Spartanburg to La Crosse?

    Currently, April is the cheapest month in which you can book a flight from Spartanburg to La Crosse (average of $266). Flying from Spartanburg to La Crosse in December is currently the most expensive (average of $1,194). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near La Crosse?

Book flights to La Crosse if you plan to visit one of these locations
Decorah
Winona

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Top airline flying from Spartanburg to La Crosse

Discover the top airline that operate flights from Spartanburg to La Crosse. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$415Average$463FlexibilityNo cancel feeOn-time71%

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