In terms of precipitation, rainfall in La Crosse ranges from 1.1 - 4.3 inches per month. June is typically the wettest month, when rainfall can reach 4.3 in. January is typically the driest time to visit La Crosse when rainfall is around 1.1 in.

If weather is an important factor for your trip to La Crosse, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 17.6 F).

What is the cheapest time of day to fly from MO to LSE?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to La Crosse as you normally would.

What airport do you fly into for flights to La Crosse from Missouri?

Most people fly into La Crosse (LSE) if they book a flight to La Crosse from Missouri. La Crosse is conveniently located just 5.4 mi from La Crosse’s city center.

Can I find deals for flights from Missouri to La Crosse that include hotel bookings?

Yes. In addition to deals on Missouri to La Crosse flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Missouri to La Crosse?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to La Crosse.

Can I find deals for business class flights from Missouri to La Crosse?

Yes. Cheapflights offers flight deals from Missouri to La Crosse by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$468+ Flights from Missouri to La Crosse

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Cheap flight deals from Missouri to La Crosse

Round-trip from	$468 (American Airlines)

From Missouri to La Crosse

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Find flight deals from Missouri to La Crosse

Cheapest flights from Missouri to La Crosse
Explore the most affordable flight options available from Missouri to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

Sat 10/41:03 pmMCI - LSE

1 stop4h 48mAmerican Airlines

Tue 10/76:00 amLSE - MCI

1 stop7h 00mAmerican Airlines

Deal found 7/29

$468

Best flights from Missouri to La Crosse
Discover carefully curated flight deals from Missouri to La Crosse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 31, 2025.

Sat 10/41:03 pmMCI - LSE

1 stop4h 48mAmerican Airlines

Tue 10/76:00 amLSE - MCI

1 stop7h 00mAmerican Airlines

Deal found 7/29

$468

Fly from

Fly to

Route

Depart

Return

Price

Kansas CityLa Crosse

MCI - LSE

MCILSE

Kansas City

Sat 10/4

1:03 pm-5:51 pm

1 stop4h 48m

La Crosse

Tue 10/7

6:00 am-1:00 pm

1 stop7h 00m

$468

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Best time to book a flight from Missouri to La Crosse

Have a flexible travel schedule? Discover the best time to fly to La Crosse from Missouri with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to La Crosse

No data available for this route at this time. Please check back soon.

Reviews of airlines servicing La Crosse

Get a feel of what it's like to fly with American Airlines from Missouri to La Crosse by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

American Airlines

7.2

Good

10,000 reviews

Reviews

1 / 20

2.0

Mediocre

Andrew,May 2025

LAX - MIA

2 hour delay. Discovered an engine problem late, we boarded the plane and they asked us to come off. To add insult to injury nothing was given to passengers to make amends. No free drink. No extra food or snacks. No free WiFi. Gimme a break

American Airlines

7.2

Good

10,000 reviews

American Airlines

7.2

Good

10,000 reviews

Reviews

1 / 20

2.0

Mediocre

Andrew,May 2025

LAX - MIA

Related info for your journey

What airport do you fly into for flights to La Crosse from Missouri?
Most people fly into La Crosse (LSE) if they book a flight to La Crosse from Missouri. La Crosse is conveniently located just 5.4 mi from La Crosse’s city center.
Can I find deals for flights from Missouri to La Crosse that include hotel bookings?
Yes. In addition to deals on Missouri to La Crosse flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Missouri to La Crosse?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to La Crosse.
Can I find deals for business class flights from Missouri to La Crosse?
Yes. Cheapflights offers flight deals from Missouri to La Crosse by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Missouri to La Crosse

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Top airline flying from Missouri to La Crosse

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$406	Average$510	FlexibilityNo cancel fee	On-time71%

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$468+ Cheap flights from Missouri to La Crosse (LSE)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/4. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Missouri to La Crosse with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Missouri to La Crosse

Keep the following information in mind while searching for Missouri to La Crosse flight deals. Data was last updated July 31, 2025.

Round-trip from

Find flight deals from Missouri to La Crosse

Cheapest flights from Missouri to La CrosseExplore the most affordable flight options available from Missouri to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

Explore the most affordable flight options available from Missouri to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Missouri to La Crosse that are best for you.

Best time to book a flight from Missouri to La Crosse

Have a flexible travel schedule? Discover the best time to fly to La Crosse from Missouri with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Missouri to La Crosse

Reviews of airlines servicing La Crosse

Get a feel of what it's like to fly with American Airlines from Missouri to La Crosse by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Missouri to La Crosse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to La Crosse from Missouri?

Can I find deals for flights from Missouri to La Crosse that include hotel bookings?

How can I find direct flights from Missouri to La Crosse?

Can I find deals for business class flights from Missouri to La Crosse?

Traveling to a place near La Crosse?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Missouri to La Crosse

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from Missouri to La Crosse

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Book with Flexibility

Travel Smart

Cheapest flights from Missouri to La Crosse
Explore the most affordable flight options available from Missouri to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.