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$284+ Cheap flights from Tucson to Knoxville (TUS - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/26. Fares are subject to change and may not be available on all flights or dates of travel.
TUS — TYS
Nov 15 — Nov 221
Sat 11/15
Sat 11/22
1 adult, Economy
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Cheap flight deals from Tucson to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Tucson (TUS) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 16, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$389
(Delta)

One-way from

$284
(United Airlines)

Popular in

October

Cheapest in

January

Average price

$604
Provider with most accurate pricing for Tucson-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Tucson-Knoxville McGhee Tyson flights.
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From Tucson to Knoxville McGhee Tyson
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One-way flight from Tucson to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 19% potential increase in price ($93 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($19 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Tucson to Knoxville

Cheapest flights from Tucson to Knoxville
Explore the most affordable flight options available from Tucson to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 16, 2025.

This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/224:43 pmTUS - TYS
1 stop5h 09mAmerican Airlines
Thu 12/45:24 amTYS - TUS
1 stop6h 12mAmerican Airlines
Deal found 10/15$413
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/119:00 amTUS - TYS
1 stop6h 29mAmerican Airlines
Mon 12/156:18 pmTYS - TUS
1 stop6h 29mAmerican Airlines
Deal found 10/15$437
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/305:00 amTUS - TYS
1 stop5h 36mAmerican Airlines
Mon 11/36:18 pmTYS - TUS
1 stop6h 32mAmerican Airlines
Deal found 10/14$537
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/307:15 amTUS - TYS
2 stops12h 40mUnited Airlines
Mon 11/36:45 amTYS - TUS
2 stops8h 52mUnited Airlines
Deal found 10/14$660
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/296:00 amTUS - TYS
1 stop15h 52mAmerican Airlines
Fri 12/56:18 pmTYS - TUS
1 stop17h 19mAmerican Airlines
Deal found 10/16$731
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/258:00 amTUS - TYS
1 stop13h 52mAmerican Airlines
Sat 11/295:10 amTYS - TUS
1 stop12h 42mAmerican Airlines
Deal found 10/15$888
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/297:00 amTUS - TYS
1 stop5h 42mUnited Airlines
Fri 12/57:25 pmTYS - TUS
2 stops20h 06mUnited Airlines
Deal found 10/16$893

Cheapflights Fare Finder

 
Customize your flight search to find flights from Tucson to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 16, 2025.
Use the filters below to find and compare flights from Tucson to Knoxville that are best for you.

Fly from

Tucson

Fly to

Knoxville

Route

Depart

Return

Price

TucsonKnoxville

TUS - TYS

TUSTYS

Tucson

Sat 11/22

4:43 pm-11:52 pm

1 stop5h 09m

Knoxville McGhee Tyson

Thu 12/4

5:24 am-9:36 am

1 stop6h 12m

$413

TucsonKnoxville

TUS - TYS

TUSTYS

Tucson

Thu 12/11

9:00 am-5:29 pm

1 stop6h 29m

Knoxville McGhee Tyson

Mon 12/15

6:18 pm-10:47 pm

1 stop6h 29m

$437

TucsonKnoxville

TUS - TYS

TUSTYS

Tucson

Thu 10/30

5:00 am-1:36 pm

1 stop5h 36m

Knoxville McGhee Tyson

Mon 11/3

6:18 pm-10:50 pm

1 stop6h 32m

$537

TucsonKnoxville

TUS - TYS

TUSTYS

Tucson

Thu 10/30

7:15 am-10:55 pm

2 stops12h 40m

Knoxville McGhee Tyson

Mon 11/3

6:45 am-1:37 pm

2 stops8h 52m

$660

TucsonKnoxville

TUS - TYS

TUSTYS

Tucson

Sat 11/29

6:00 am-11:52 pm

1 stop15h 52m

Knoxville McGhee Tyson

Fri 12/5

6:18 pm-9:37 am

1 stop17h 19m

$731

TucsonKnoxville

TUS - TYS

TUSTYS

Tucson

Sat 11/29

7:00 am-2:42 pm

1 stop5h 42m

Knoxville McGhee Tyson

Fri 12/5

7:25 pm-1:31 pm

2 stops20h 06m

$893

TucsonKnoxville

TUS - TYS

TUSTYS

Tucson

Tue 11/25

2:41 pm-11:52 pm

1 stop7h 11m

Knoxville McGhee Tyson

Sat 11/29

5:10 am-9:39 am

1 stop6h 29m

$902

TucsonKnoxville

TUS - TYS

TUSTYS

Tucson

Tue 11/25

8:15 am-11:59 pm

2 stops13h 44m

Knoxville McGhee Tyson

Sat 11/29

4:50 pm-10:34 pm

1 stop7h 44m

$910

TucsonKnoxville

TUS - TYS

TUSTYS

Tucson

Wed 11/26

2:40 pm-10:30 pm

1 stop5h 50m

$284

TucsonKnoxville

TUS - TYS

TUSTYS

Tucson

Tue 10/21

3:59 pm-12:23 am

1 stop5h 24m

$369

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/14

Showing 1-10 of 17 results
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Compare providers for flights from Tucson to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Tucson to Knoxville in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Tucson-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Tucson-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Tucson-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Tucson-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Tucson-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Tucson to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Tucson with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Tucson to Knoxville

What is the cheapest month to book a flight from Tucson to Knoxville?

Currently, April is the cheapest month in which you can book a flight from Tucson to Knoxville (average of $228). Flying from Tucson to Knoxville in September is currently the most expensive (average of $303). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TUS to TYS?

Find hourly flight availability from Tucson to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 16, 2025.

When flying from Tucson to Knoxville, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 27% versus a flight in the evening.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated October 16, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Tucson to Knoxville to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,984 reviews

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

7.9

Food

7.3

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
8.0
Very good
7,984 reviews
Delta
8.0
Very good
7,984 reviews

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

7.9

Food

7.3

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,982 reviews
Delta
8.0
Very good
7,984 reviews

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

7.9

Food

7.3

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,043 reviews
Delta
8.0
Very good
7,984 reviews

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

7.9

Food

7.3

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Tucson to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Tucson to Knoxville?

    There are many flights that can get you from Tucson to Knoxville in 5h 09m. Fly via American Airlines to get the fastest option. Airlines will cover a distance of 1559 mi.

  • What are the cheapest airlines flying from Tucson to Knoxville round-trip?

    According to our current data, Delta ($282), American Airlines ($288), and United Airlines ($313) offers the cheapest pricing from Tucson to Knoxville. You may be able to fly from Tucson to Knoxville for 29% less than the average price by searching for these airlines.

  • Can I find deals for flights from Tucson to Knoxville that include hotel bookings?

    Yes. In addition to deals on Tucson to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Tucson to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Tucson to Knoxville.

  • Can I find deals for business class flights from Tucson to Knoxville?

    Yes. Cheapflights offers flight deals from Tucson to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Tucson to Knoxville?

    Currently, April is the cheapest month in which you can book a flight from Tucson to Knoxville (average of $228). Flying from Tucson to Knoxville in September is currently the most expensive (average of $303). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

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Top 3 airlines flying from Tucson to Knoxville

Discover the top 3 airlines that operate flights from Tucson to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$282Average$353FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$288Average$364FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$313Average$564FlexibilityNo cancel feeOn-time69%

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