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Knoxville

$375+ Cheap flights from Tucson to Knoxville (TUS - TYS)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/5. Fares are subject to change and may not be available on all flights or dates of travel.
TUS — TYS
Apr 22 — Apr 291
Wed 4/22
Wed 4/29
1 adult, Economy
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Cheap flight deals from Tucson to Knoxville

Cheapest flights from Tucson to Knoxville
Explore the most affordable flight options available from Tucson to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 23, 2026.

This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:02 am
TUS
-
TYS
1 stop6h 16m
American Airlines
Tue 5/124:09 pm
TYS
-
TUS
1 stop8h 34m
American Airlines
Deal found 3/19$375
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:10 am
TUS
-
TYS
1 stop6h 07m
American Airlines
Sat 5/166:00 am
TYS
-
TUS
1 stop5h 59m
American Airlines
Deal found 3/20$405
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:35 am
TUS
-
TYS
2 stops10h 05m
Southwest
Tue 5/127:05 am
TYS
-
TUS
2 stops9h 35m
Southwest
Deal found 3/19$415
This American Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/171:15 pm
TUS
-
TYS
1 stop7h 03m
American Airlines
Sat 10/241:40 pm
TYS
-
TUS
1 stop8h 33m
American Airlines
Deal found 3/23$429
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:00 am
TUS
-
TYS
1 stop6h 06m
United Airlines
Sat 4/257:00 am
TYS
-
TUS
2 stops11h 04m
United Airlines
Deal found 3/19$436
This Southwest deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/99:25 am
TUS
-
TYS
1 stop7h 10m
Southwest
Sat 5/166:40 am
TYS
-
TUS
2 stops12h 00m
Southwest
Deal found 3/20$440
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:30 am
TUS
-
TYS
1 stop8h 35m
United Airlines
Mon 8/244:56 pm
TYS
-
TUS
1 stop6h 19m
United Airlines
Deal found 3/19$443
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/185:35 am
TUS
-
TYS
2 stops7h 55m
Southwest
Mon 8/242:05 pm
TYS
-
TUS
2 stops10h 35m
Southwest
Deal found 3/19$453

Find flight deals from Tucson to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Tucson (TUS) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 23, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$375
(American Airlines)

Popular in

November

Cheapest in

July

Average price

$509
Provider with most accurate pricing for Tucson-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Tucson-Knoxville McGhee Tyson flights.
Search Deals
From Tucson to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 27% potential increase in price ($187 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($25 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Tucson to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 23, 2026.
Use the filters below to find and compare flights from Tucson to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

TucsonKnoxville

TUS - TYS

TUSTYS

Tucson

Tue 5/5

6:35 am-7:40 pm

2 stops10h 05m

Knoxville McGhee Tyson

Tue 5/12

7:05 am-1:40 pm

2 stops9h 35m

$415

TucsonKnoxville

TUS - TYS

TUSTYS

Tucson

Tue 9/15

6:00 am-3:07 pm

1 stop6h 07m

Knoxville McGhee Tyson

Mon 9/21

4:00 pm-9:37 pm

1 stop8h 37m

$443
Quickest round-trip

TucsonKnoxville

TUS - TYS

TUSTYS

Tucson

Tue 5/19

1:39 pm-10:23 pm

1 stop5h 44m

Knoxville McGhee Tyson

Thu 5/28

4:56 pm-8:12 pm

1 stop6h 16m

$443

TucsonKnoxville

TUS - TYS

TUSTYS

Tucson

Tue 8/18

9:30 am-8:48 pm

2 stops8h 18m

Knoxville McGhee Tyson

Mon 8/24

4:56 pm-8:15 pm

1 stop6h 19m

$448

TucsonKnoxville

TUS - TYS

TUSTYS

Tucson

Tue 9/15

7:00 am-4:30 pm

1 stop6h 30m

Knoxville McGhee Tyson

Mon 9/21

2:05 pm-9:40 pm

2 stops10h 35m

$448

TucsonKnoxville

TUS - TYS

TUSTYS

Tucson

Mon 8/17

6:00 am-3:07 pm

1 stop6h 07m

Knoxville McGhee Tyson

Sun 8/23

5:57 pm-9:37 pm

1 stop6h 40m

$457

TucsonKnoxville

TUS - TYS

TUSTYS

Tucson

Tue 5/5

8:50 am-10:23 pm

2 stops10h 33m

Knoxville McGhee Tyson

Tue 5/12

7:00 am-11:32 am

1 stop7h 32m

$487

TucsonKnoxville

TUS - TYS

TUSTYS

Tucson

Wed 4/15

6:00 am-3:06 pm

1 stop6h 06m

Knoxville McGhee Tyson

Sat 4/18

5:15 pm-9:22 pm

1 stop7h 07m

$490

TucsonKnoxville

TUS - TYS

TUSTYS

Tucson

Mon 8/17

9:30 am-9:30 pm

2 stops9h 00m

Knoxville McGhee Tyson

Sun 8/23

4:56 pm-8:15 pm

1 stop6h 19m

$491
Cheapest one-way
Quickest one-way

TucsonKnoxville

TUS - TYS

TUSTYS

Tucson

Thu 4/16

6:00 am-5:08 pm

1 stop8h 08m

$505

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/20

Showing 1-10 of 11 resultsSorted by cheapest first
1
2

Compare providers for flights from Tucson to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Tucson to Knoxville in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Tucson-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Tucson-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Tucson-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Tucson-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Tucson-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Tucson to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Tucson with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Tucson to Knoxville

What is the cheapest month to book a flight from Tucson to Knoxville?

Currently, June is the cheapest month in which you can book a flight from Tucson to Knoxville (average of $244). Flying from Tucson to Knoxville in November is currently the most expensive (average of $392). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated March 23, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAmerican Airlines from Tucson to Knoxville to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,320 reviews

Entertainment

7.8

Overall

7.9

Boarding

8.1

Comfort

7.9

Crew

8.5

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,320 reviews
Delta
7.9
Good
8,320 reviews

Entertainment

7.8

Overall

7.9

Boarding

8.1

Comfort

7.9

Crew

8.5

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,467 reviews
Delta
7.9
Good
8,320 reviews

Entertainment

7.8

Overall

7.9

Boarding

8.1

Comfort

7.9

Crew

8.5

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,492 reviews
Delta
7.9
Good
8,320 reviews

Entertainment

7.8

Overall

7.9

Boarding

8.1

Comfort

7.9

Crew

8.5

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Tucson to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Tucson to Knoxville?

    There are many flights that can get you from Tucson to Knoxville in 5h 44m. Fly via Southwest, Delta, or United Airlines to get the fastest option. Airlines will cover a distance of 1559 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Tucson to Knoxville round-trip?

    According to our current data, Delta ($276), American Airlines ($288), and United Airlines ($313) offers the cheapest pricing from Tucson to Knoxville. You may be able to fly from Tucson to Knoxville for 44% less than the average price by searching for these airlines.

  • Can I find deals for flights from Tucson to Knoxville that include hotel bookings?

    Yes. In addition to deals on Tucson to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Tucson to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Tucson to Knoxville.

  • Can I find deals for business class flights from Tucson to Knoxville?

    Yes. Cheapflights offers flight deals from Tucson to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Tucson to Knoxville?

    Currently, June is the cheapest month in which you can book a flight from Tucson to Knoxville (average of $244). Flying from Tucson to Knoxville in November is currently the most expensive (average of $392). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Murphy
Oak Ridge

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Tucson to Knoxville

Discover the top 3 airlines that operate flights from Tucson to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 23, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$276Average$388FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$288Average$424FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$313Average$558FlexibilityNo cancel feeOn-time69%

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