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$207+ Cheap flights from Syracuse to Knoxville (SYR - TYS)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/26. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — TYS
jun. 17 — jun. 241
mar. 6/17
mar. 6/24
1 adult, Economy
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Cheapflights Tip: The best prices from Syracuse Hancock Intl to Knoxville McGhee Tyson are usually found in May or January, booked 37 days in advance, depart on a Tuesday or Wednesday and return on a Wednesday

Cheap flight deals from Syracuse to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Syracuse (SYR) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated junio 12, 2025.

Round-trip from

$207
(Mytrip)

Popular in

August

Cheapest in

May

Average price

$308
From Syracuse Hancock Intl to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 8% potential increase in price ($30 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Syracuse to Knoxville

Cheapest flights from Syracuse to Knoxville
Explore the most affordable flight options available from Syracuse to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 7/268:42 pmSYR - TYS
1 stop26h 14mAllegiant Air
vie. 8/12:13 pmTYS - SYR
1 stop20h 20mAllegiant Air
Deal found 6/10$207
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/317:46 pmSYR - TYS
1 stop4h 00mAmerican Airlines
mar. 11/44:43 pmTYS - SYR
1 stop6h 45mAmerican Airlines
Deal found 6/11$224
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 7/412:30 pmSYR - TYS
1 stop4h 10mDelta
mié. 7/96:10 amTYS - SYR
1 stop5h 39mDelta
Deal found 6/11$233
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 7/267:23 pmSYR - TYS
2 stops24h 41mMultiple Airlines
vie. 8/16:00 amTYS - SYR
2 stops27h 33mMultiple Airlines
Deal found 6/10$302
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 7/15:40 pmSYR - TYS
1 stop4h 55mUnited Airlines
mar. 7/155:45 amTYS - SYR
1 stop4h 05mUnited Airlines
Deal found 6/11$342

Cheapflights Fare Finder

Customize your flight search to find flights from Syracuse to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
Use the filters below to find and compare flights from Syracuse to Knoxville that are best for you.

Fly from

Syracuse

Fly to

Knoxville

Route

Depart

Return

Price

SyracuseKnoxville

SYR - TYS

SYRTYS

Syracuse Hancock Intl

sáb. 7/26

8:42 pm-10:56 pm

1 stop26h 14m

Knoxville McGhee Tyson

vie. 8/1

2:13 pm-10:33 am

1 stop20h 20m

$207

SyracuseKnoxville

SYR - TYS

SYRTYS

Syracuse Hancock Intl

vie. 10/31

7:46 pm-11:46 pm

1 stop4h 00m

Knoxville McGhee Tyson

mar. 11/4

4:43 pm-11:28 pm

1 stop6h 45m

$224

SyracuseKnoxville

SYR - TYS

SYRTYS

Syracuse Hancock Intl

vie. 7/4

12:30 pm-4:40 pm

1 stop4h 10m

Knoxville McGhee Tyson

mar. 7/8

11:26 am-4:58 pm

1 stop5h 32m

$233

SyracuseKnoxville

SYR - TYS

SYRTYS

Syracuse Hancock Intl

sáb. 7/26

7:23 pm-8:04 pm

2 stops24h 41m

Knoxville McGhee Tyson

vie. 8/1

6:00 am-9:33 am

2 stops27h 33m

$302

SyracuseKnoxville

SYR - TYS

SYRTYS

Syracuse Hancock Intl

mar. 7/1

7:45 pm-11:59 pm

1 stop4h 14m

Knoxville McGhee Tyson

vie. 7/4

7:00 am-6:58 pm

2 stops11h 58m

$334

SyracuseKnoxville

SYR - TYS

SYRTYS

Syracuse Hancock Intl

mié. 7/2

5:31 am-10:36 am

1 stop5h 05m

$236

SyracuseKnoxville

SYR - TYS

SYRTYS

Syracuse Hancock Intl

vie. 6/27

7:52 pm-3:48 pm

1 stop19h 56m

$253

SyracuseKnoxville

SYR - TYS

SYRTYS

Syracuse Hancock Intl

vie. 6/27

12:05 pm-9:57 pm

2 stops9h 52m

$320

SyracuseKnoxville

SYR - TYS

SYRTYS

Syracuse Hancock Intl

sáb. 7/26

6:00 am-5:05 pm

2 stops11h 05m

$365

SyracuseKnoxville

SYR - TYS

SYRTYS

Syracuse Hancock Intl

mié. 7/2

12:30 pm-10:11 pm

2 stops9h 41m

$1,037

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/12

Best time to book a flight from Syracuse to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Syracuse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to Knoxville

How far ahead should I book a flight from Syracuse to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from Syracuse to Knoxville. Price data was last updated on June 9, 2025.

Booking 37 days in advance of your planned departure date is, on average, the best time to get cheap flights from Syracuse to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Syracuse to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Syracuse to Knoxville (average of $296). Flying from Syracuse to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SYR to TYS?

Find hourly flight availability from Syracuse to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated junio 12, 2025.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 23% on flights from Syracuse to Knoxville by exploring options for tickets at noon.

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated junio 12, 2025.
Read reviews from past customers who have flown Delta, United Airlines and Allegiant Air from Syracuse to Knoxville. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
8.0
Very good
7,950 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
United Airlines
7.4
Good
8,790 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Allegiant Air
7.3
Good
725 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Syracuse to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Syracuse to Knoxville round-trip?

    Our cheapest airline available from Syracuse to Knoxville is Allegiant Air. Our recent data shows that you can find tickets from as low as $207 on this airline. Additional options worth looking into are American Airlines and Delta, starting at $224 and $233 round-trip. Allegiant Air is currently priced 39% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Syracuse to Knoxville one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $236. However, be on the lookout for offers from Allegiant Air and United Airlines, as they are both options that can get you from Syracuse to Knoxville for a low price.

  • Can I find deals for flights from Syracuse to Knoxville that include hotel bookings?

    Yes. In addition to deals on Syracuse to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Syracuse to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to Knoxville.

  • Can I find deals for business class flights from Syracuse to Knoxville?

    Yes. Cheapflights offers flight deals from Syracuse to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Syracuse to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Syracuse to Knoxville (average of $296). Flying from Syracuse to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Syracuse?

Book flights to Syracuse if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Maryville
Oak Ridge
Alcoa
Murphy

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Top 3 airlines flying from Syracuse to Knoxville

Discover the top 3 airlines that operate flights from Syracuse to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$199Average$360FlexibilityNo cancel feeOn-time71%
DeltaCheapest$215Average$293FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$258Average$490FlexibilityNo cancel feeOn-time69%

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