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$220+ Cheap flights from Syracuse to Knoxville (SYR - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/30. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — TYS
May 4 — May 111
Sun 5/4
Sun 5/11
1 adult, Economy
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Find cheap flights from Syracuse to Knoxville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

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Cheapflights Tip: The best prices from Syracuse Hancock Intl to Knoxville McGhee Tyson are usually found in May or January, booked 37 days in advance, depart on a Tuesday or Wednesday and return on a Wednesday

Cheap flight deals from Syracuse to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Syracuse (SYR) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 29, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$233
(Delta)

One-way from

$220
(American Airlines)

Popular in

August

Cheapest in

May

Average price

$378
Provider with most accurate pricing for Syracuse Hancock Intl-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Syracuse Hancock Intl-Knoxville McGhee Tyson flights.
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From Syracuse Hancock Intl to Knoxville McGhee Tyson
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One-way flight from Syracuse Hancock Intl to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 5% potential increase in price ($21 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Syracuse to Knoxville

Cheapest flights from Syracuse to Knoxville
Explore the most affordable flight options available from Syracuse to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2025.

This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/296:21 pmSYR - TYS
1 stop5h 30mDelta
Mon 6/26:20 amTYS - SYR
1 stop5h 16mDelta
Deal found 4/28$233
This Mytrip deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/96:37 pmSYR - TYS
1 stop26h 35mAllegiant Air
Fri 5/162:01 pmTYS - SYR
1 stop20h 17mAllegiant Air
Deal found 4/27$248
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1312:47 pmSYR - TYS
2 stops6h 27mAmerican Airlines
Wed 5/217:44 pmTYS - SYR
1 stop4h 05mAmerican Airlines
Deal found 4/27$259
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/76:09 amSYR - TYS
2 stops7h 13mUnited Airlines
Thu 5/157:00 amTYS - SYR
1 stop6h 41mUnited Airlines
Deal found 4/28$359
This Mytrip deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/126:37 pmSYR - TYS
1 stop21h 54mMultiple Airlines
Fri 5/168:00 amTYS - SYR
2 stops30h 02mMultiple Airlines
Deal found 4/27$396

Cheapflights Fare Finder

Customize your flight search to find flights from Syracuse to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2025.
Use the filters below to find and compare flights from Syracuse to Knoxville that are best for you.

Fly from

Syracuse

Fly to

Knoxville

Route

Depart

Return

Price

SyracuseKnoxville

SYR - TYS

SYRTYS

Syracuse Hancock Intl

Thu 5/29

6:21 pm-11:51 pm

1 stop5h 30m

Knoxville McGhee Tyson

Mon 6/2

6:20 am-11:36 am

1 stop5h 16m

$233

SyracuseKnoxville

SYR - TYS

SYRTYS

Syracuse Hancock Intl

Fri 5/9

6:37 pm-9:12 pm

1 stop26h 35m

Knoxville McGhee Tyson

Fri 5/16

2:01 pm-10:18 am

1 stop20h 17m

$248

SyracuseKnoxville

SYR - TYS

SYRTYS

Syracuse Hancock Intl

Thu 5/29

1:48 pm-7:14 pm

2 stops5h 26m

Knoxville McGhee Tyson

Mon 6/2

7:44 pm-11:49 pm

1 stop4h 05m

$284

SyracuseKnoxville

SYR - TYS

SYRTYS

Syracuse Hancock Intl

Tue 7/22

10:25 am-10:35 pm

2 stops12h 10m

Knoxville McGhee Tyson

Sat 7/26

6:58 pm-11:59 pm

1 stop5h 01m

$324

SyracuseKnoxville

SYR - TYS

SYRTYS

Syracuse Hancock Intl

Fri 5/9

12:05 pm-4:03 pm

3 stops27h 58m

Knoxville McGhee Tyson

Fri 5/16

2:01 pm-10:18 am

1 stop20h 17m

$530

SyracuseKnoxville

SYR - TYS

SYRTYS

Syracuse Hancock Intl

Mon 6/30

5:06 am-10:43 am

1 stop5h 37m

$220

SyracuseKnoxville

SYR - TYS

SYRTYS

Syracuse Hancock Intl

Sun 5/18

6:00 am-2:35 pm

2 stops8h 35m

$365

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/28

Compare providers for flights from Syracuse to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Syracuse to Knoxville in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*2 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Syracuse-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Syracuse-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Syracuse-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Syracuse-Knoxville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Syracuse-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Syracuse to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Syracuse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to Knoxville

How far ahead should I book a flight from Syracuse to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from Syracuse to Knoxville. Price data was last updated on April 25, 2025.

Booking 37 days in advance of your planned departure date is, on average, the best time to get cheap flights from Syracuse to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Syracuse to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Syracuse to Knoxville (average of $296). Flying from Syracuse to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SYR to TYS?

Find hourly flight availability from Syracuse to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 29, 2025.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 23% on flights from Syracuse to Knoxville by exploring options for tickets at noon.

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated April 29, 2025.
Read reviews from past customers who have flown Delta, United Airlines and Allegiant Air from Syracuse to Knoxville. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,929 reviews

Boarding

8.2

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
8.0
Very good
7,929 reviews
Delta
8.0
Very good
7,929 reviews

Boarding

8.2

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very good
7,929 reviews

Boarding

8.2

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Allegiant Air
7.3
Good
734 reviews
Delta
8.0
Very good
7,929 reviews

Boarding

8.2

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,929 reviews

Boarding

8.2

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Syracuse to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Syracuse to Knoxville round-trip?

    Our cheapest airline available from Syracuse to Knoxville is Delta. Our recent data shows that you can find tickets from as low as $233 on this airline. Additional options worth looking into are Allegiant Air and American Airlines, starting at $248 and $259 round-trip. Delta is currently priced 34% below the average price you’ll pay for this route.

  • Can I find deals for flights from Syracuse to Knoxville that include hotel bookings?

    Yes. In addition to deals on Syracuse to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Syracuse to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to Knoxville.

  • Can I find deals for business class flights from Syracuse to Knoxville?

    Yes. Cheapflights offers flight deals from Syracuse to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Syracuse to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Syracuse to Knoxville (average of $296). Flying from Syracuse to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Syracuse?

Book flights to Syracuse if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Maryville
Oak Ridge
Alcoa
Murphy

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Top 3 airlines flying from Syracuse to Knoxville

Discover the top 3 airlines that operate flights from Syracuse to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$211Average$291FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$223Average$383FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$258Average$417FlexibilityNo cancel feeOn-time69%

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