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Knoxville

$95+ Cheap flights from Ohio to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/8. Fares are subject to change and may not be available on all flights or dates of travel.
CVG — TYS
Aug 5 — Aug 121
Tue 8/5
Tue 8/12
1 adult, Economy
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Cheap flight deals from Ohio to Knoxville

Keep the following information in mind while searching for Ohio to Knoxville flight deals. Data was last updated July 31, 2025.

Round-trip from

$184
(Mytrip)

One-way from

$95
(Mytrip)

Popular in

March

Cheapest in

February

Average price

$279
From Ohio to Knoxville McGhee Tyson
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One-way flight from Ohio to Knoxville McGhee Tyson
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High demand for flights, 0% potential price rise
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Cheapest flight prices on average. 2% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Ohio to Knoxville

Cheapest flights from Ohio to Knoxville
Explore the most affordable flight options available from Ohio to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

This Mytrip deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/47:00 amPIT - TYS
1 stop11h 45mMultiple Airlines
Tue 9/97:30 amTYS - PIT
2 stops15h 52mMultiple Airlines
Deal found 7/29$184
This Mytrip deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/226:00 amCMH - TYS
1 stop11h 38mMultiple Airlines
Mon 8/251:22 pmTYS - CMH
1 stop8h 24mMultiple Airlines
Deal found 7/30$187
This Mytrip deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/87:02 amDTW - TYS
1 stop10h 32mMultiple Airlines
Fri 9/121:22 pmTYS - DTW
1 stop9h 18mMultiple Airlines
Deal found 7/30$208
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/235:56 pmPIT - TYS
1 stop5h 52mDelta
Sat 8/306:14 pmTYS - PIT
1 stop4h 56mDelta
Deal found 7/30$214
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/26:00 amCMH - TYS
1 stop5h 22mAmerican Airlines
Sat 9/64:53 pmTYS - CMH
1 stop4h 32mAmerican Airlines
Deal found 7/31$219
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/241:19 pmCVG - TYS
1 stop6h 26mAmerican Airlines
Sun 8/313:04 pmTYS - CVG
1 stop4h 53mAmerican Airlines
Deal found 7/31$219
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/187:45 pmCMH - TYS
1 stop4h 03mDelta
Mon 8/257:50 amTYS - CMH
1 stop5h 39mDelta
Deal found 7/31$224
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/202:57 pmCAK - TYS
1 stop4h 08mAmerican Airlines
Wed 9/2412:15 pmTYS - CAK
1 stop5h 16mAmerican Airlines
Deal found 7/30$229
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/245:20 amCLE - TYS
1 stop5h 44mDelta
Sun 10/268:10 pmTYS - CLE
1 stop4h 26mDelta
Deal found 7/29$229
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/204:19 pmCLE - TYS
2 stops6h 44mAmerican Airlines
Wed 9/248:23 amTYS - CLE
1 stop4h 08mAmerican Airlines
Deal found 7/30$234
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/124:00 pmCVG - TYS
1 stop5h 17mDelta
Sat 8/165:45 amTYS - CVG
1 stop5h 55mDelta
Deal found 7/30$234
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/145:03 amPIT - TYS
1 stop5h 27mAmerican Airlines
Mon 8/185:12 pmTYS - PIT
1 stop4h 37mAmerican Airlines
Deal found 7/29$239

Cheapflights Fare Finder

 
Customize your flight search to find flights from Ohio to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Ohio to Knoxville that are best for you.

Fly from

Ohio

Fly to

Knoxville

Route

Depart

Return

Price

PittsburghKnoxville

PIT - TYS

PITTYS

Pittsburgh

Thu 9/4

7:00 am-6:45 pm

1 stop11h 45m

Knoxville McGhee Tyson

Tue 9/9

7:30 am-11:22 pm

2 stops15h 52m

$184

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Fri 8/22

6:00 am-5:38 pm

1 stop11h 38m

Knoxville McGhee Tyson

Mon 8/25

1:22 pm-9:46 pm

1 stop8h 24m

$187

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Mon 9/8

7:02 am-5:34 pm

1 stop10h 32m

Knoxville McGhee Tyson

Fri 9/12

1:22 pm-10:40 pm

1 stop9h 18m

$208

PittsburghKnoxville

PIT - TYS

PITTYS

Pittsburgh

Sat 8/23

5:56 pm-11:48 pm

1 stop5h 52m

Knoxville McGhee Tyson

Sat 8/30

6:14 pm-11:10 pm

1 stop4h 56m

$214

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Tue 9/2

6:00 am-11:22 am

1 stop5h 22m

Knoxville McGhee Tyson

Sat 9/6

4:53 pm-9:25 pm

1 stop4h 32m

$219

CincinnatiKnoxville

CVG - TYS

CVGTYS

Cincinnati Cinci./N. Kentucky

Sun 8/24

1:19 pm-7:45 pm

1 stop6h 26m

Knoxville McGhee Tyson

Sun 8/31

3:04 pm-7:57 pm

1 stop4h 53m

$219

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Mon 8/18

7:45 pm-11:48 pm

1 stop4h 03m

Knoxville McGhee Tyson

Mon 8/25

7:50 am-1:29 pm

1 stop5h 39m

$224

AkronKnoxville

CAK - TYS

CAKTYS

Akron/Canton

Sat 9/20

2:57 pm-7:05 pm

1 stop4h 08m

Knoxville McGhee Tyson

Wed 9/24

12:15 pm-5:31 pm

1 stop5h 16m

$229

ClevelandKnoxville

CLE - TYS

CLETYS

Cleveland Hopkins Intl

Fri 10/24

4:00 pm-9:13 pm

1 stop5h 13m

Knoxville McGhee Tyson

Tue 10/28

6:30 am-12:13 pm

1 stop5h 43m

$229

ClevelandKnoxville

CLE - TYS

CLETYS

Cleveland Hopkins Intl

Sat 9/20

4:19 pm-11:03 pm

2 stops6h 44m

Knoxville McGhee Tyson

Wed 9/24

8:23 am-12:31 pm

1 stop4h 08m

$234

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/30

Showing 1-10 of 50 results
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Best time to book a flight from Ohio to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Ohio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ohio to Knoxville

What is the cheapest month to book a flight from Ohio to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Ohio to Knoxville (average of $294). Flying from Ohio to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from OH to TYS?

Find hourly flight availability from Ohio to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 31, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Ohio to Knoxville as you normally would.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated July 31, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Ohio to Knoxville by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,980 reviews

Comfort

7.9

Overall

8.0

Crew

8.5

Entertainment

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,980 reviews
Delta
8.0
Very good
7,980 reviews

Comfort

7.9

Overall

8.0

Crew

8.5

Entertainment

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,902 reviews
Delta
8.0
Very good
7,980 reviews

Comfort

7.9

Overall

8.0

Crew

8.5

Entertainment

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,980 reviews

Comfort

7.9

Overall

8.0

Crew

8.5

Entertainment

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Allegiant Air
7.2
Good
702 reviews
Delta
8.0
Very good
7,980 reviews

Comfort

7.9

Overall

8.0

Crew

8.5

Entertainment

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Frontier
5.9
Fair
3,238 reviews
Delta
8.0
Very good
7,980 reviews

Comfort

7.9

Overall

8.0

Crew

8.5

Entertainment

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Ohio to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Ohio?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson (TYS) is the airport most travelers will use when flying to Knoxville from Ohio.

  • What are the cheapest airlines to fly from Ohio to Knoxville one-way?

    The cheapest airlines for a one-way flight from Ohio to Knoxville are Allegiant Air ($97), Frontier ($119), and American Airlines ($126).

  • What are the most popular routes from Ohio to Knoxville?

    Most travelers choose Detroit Metropolitan Wayne County - Knoxville McGhee Tyson, Cleveland Hopkins Intl - Knoxville McGhee Tyson or Pittsburgh - Knoxville McGhee Tyson when deciding on the best route from Ohio to Knoxville.

  • Can I find deals for flights from Ohio to Knoxville that include hotel bookings?

    Yes. In addition to deals on Ohio to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ohio to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to Knoxville.

  • Can I find deals for business class flights from Ohio to Knoxville?

    Yes. Cheapflights offers flight deals from Ohio to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Ohio to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Ohio to Knoxville (average of $294). Flying from Ohio to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

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Alternative routes for Ohio to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Ohio to Knoxville

Discover the top 3 airlines that operate flights from Ohio to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$198Average$271FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$198Average$327FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$213Average$299FlexibilityNo cancel feeOn-time71%

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