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Knoxville

$116+ Cheap flights from Ohio to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/29. Fares are subject to change and may not be available on all flights or dates of travel.
CVG — TYS
May 6 — May 131
Tue 5/6
Tue 5/13
1 adult, Economy
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Cheap flight deals from Ohio to Knoxville

Keep the following information in mind while searching for Ohio to Knoxville flight deals. Data was last updated May 1, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$190
(Mytrip)

One-way from

$116
(Frontier)

Popular in

March

Cheapest in

February

Average price

$318
Provider with most accurate pricing for Cleveland Hopkins Intl-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Cleveland Hopkins Intl-Knoxville McGhee Tyson flights.
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From Ohio to Knoxville McGhee Tyson
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One-way flight from Ohio to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 0% potential increase in price ($2 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in May 2025
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Find flight deals from Ohio to Knoxville

Cheapest flights from Ohio to Knoxville
Explore the most affordable flight options available from Ohio to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

This Mytrip deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/285:54 amPIT - TYS
1 stop11h 09mMultiple Airlines
Wed 6/47:10 amTYS - PIT
1 stop26h 10mMultiple Airlines
Deal found 4/30$190
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/286:00 amCVG - TYS
1 stop5h 23mDelta
Wed 6/410:25 amTYS - CVG
1 stop4h 39mDelta
Deal found 4/30$209
This Mytrip deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/239:47 amDTW - TYS
1 stop10h 53mMultiple Airlines
Fri 5/3012:45 pmTYS - DTW
1 stop8h 57mMultiple Airlines
Deal found 4/30$210
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2811:11 amPIT - TYS
1 stop6h 10mAmerican Airlines
Sun 6/16:00 amTYS - PIT
1 stop6h 17mAmerican Airlines
Deal found 4/30$214
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/286:05 amCMH - TYS
1 stop3h 08mDelta
Tue 9/27:30 amTYS - CMH
1 stop3h 49mDelta
Deal found 4/29$219
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/301:39 pmCVG - TYS
1 stop4h 23mAmerican Airlines
Fri 6/61:06 pmTYS - CVG
1 stop7h 14mAmerican Airlines
Deal found 4/30$219
This Frontier deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/56:00 amDTW - TYS
1 stop10h 29mFrontier
Sun 6/85:25 pmTYS - DTW
1 stop7h 19mFrontier
Deal found 4/30$220
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2012:26 pmCMH - TYS
1 stop6h 48mAmerican Airlines
Sun 5/256:00 amTYS - CMH
1 stop5h 56mAmerican Airlines
Deal found 4/30$224
This Mytrip deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/56:59 pmCMH - TYS
1 stop13h 20mMultiple Airlines
Mon 6/96:00 amTYS - CMH
1 stop17h 32mMultiple Airlines
Deal found 4/30$227
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/278:00 pmPIT - TYS
1 stop3h 59mUnited Airlines
Tue 6/310:50 amTYS - PIT
1 stop6h 06mUnited Airlines
Deal found 4/30$229
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/61:00 pmCLE - TYS
1 stop7h 40mDelta
Fri 6/137:44 pmTYS - CLE
1 stop3h 51mDelta
Deal found 4/30$229
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/165:53 pmCLE - TYS
1 stop5h 33mAmerican Airlines
Mon 5/197:44 pmTYS - CLE
1 stop4h 14mAmerican Airlines
Deal found 4/30$239

Cheapflights Fare Finder

Customize your flight search to find flights from Ohio to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
Use the filters below to find and compare flights from Ohio to Knoxville that are best for you.

Fly from

Ohio

Fly to

Knoxville

Route

Depart

Return

Price

PittsburghKnoxville

PIT - TYS

PITTYS

Pittsburgh

Wed 5/28

5:54 am-5:03 pm

1 stop11h 09m

Knoxville McGhee Tyson

Wed 6/4

7:10 am-9:20 am

1 stop26h 10m

$190

CincinnatiKnoxville

CVG - TYS

CVGTYS

Cincinnati Cinci./N. Kentucky

Wed 5/28

6:00 am-11:23 am

1 stop5h 23m

Knoxville McGhee Tyson

Wed 6/4

10:25 am-3:04 pm

1 stop4h 39m

$209

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Fri 5/23

9:47 am-8:40 pm

1 stop10h 53m

Knoxville McGhee Tyson

Fri 5/30

12:45 pm-9:42 pm

1 stop8h 57m

$210

PittsburghKnoxville

PIT - TYS

PITTYS

Pittsburgh

Wed 5/28

11:11 am-5:21 pm

1 stop6h 10m

Knoxville McGhee Tyson

Sun 6/1

6:00 am-12:17 pm

1 stop6h 17m

$214

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Thu 7/24

6:37 pm-11:59 pm

1 stop5h 22m

Knoxville McGhee Tyson

Sun 7/27

5:30 am-11:26 am

1 stop5h 56m

$219

CincinnatiKnoxville

CVG - TYS

CVGTYS

Cincinnati Cinci./N. Kentucky

Fri 5/30

1:39 pm-6:02 pm

1 stop4h 23m

Knoxville McGhee Tyson

Fri 6/6

1:06 pm-8:20 pm

1 stop7h 14m

$219

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Thu 6/5

6:00 am-4:29 pm

1 stop10h 29m

Knoxville McGhee Tyson

Sun 6/8

5:25 pm-12:44 am

1 stop7h 19m

$220

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Sat 5/24

5:25 am-10:55 pm

1 stop17h 30m

Knoxville McGhee Tyson

Mon 5/26

6:00 am-11:27 am

1 stop5h 27m

$221

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Tue 5/20

12:26 pm-7:14 pm

1 stop6h 48m

Knoxville McGhee Tyson

Sun 5/25

6:00 am-11:56 am

1 stop5h 56m

$224

PittsburghKnoxville

PIT - TYS

PITTYS

Pittsburgh

Tue 5/27

8:00 pm-11:59 pm

1 stop3h 59m

Knoxville McGhee Tyson

Tue 6/3

10:50 am-4:56 pm

1 stop6h 06m

$229

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Showing 1-10 of 46 results
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Best time to book a flight from Ohio to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Ohio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ohio to Knoxville

What is the cheapest month to book a flight from Ohio to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Ohio to Knoxville (average of $296). Flying from Ohio to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from OH to TYS?

Find hourly flight availability from Ohio to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Ohio to Knoxville as you normally would.

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated May 1, 2025.
Read reviews from past customers who have flown Delta, United Airlines and Allegiant Air from Ohio to Knoxville. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,934 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,934 reviews
Delta
8.0
Very good
7,934 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very good
7,934 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Allegiant Air
7.3
Good
734 reviews
Delta
8.0
Very good
7,934 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,934 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Frontier
6.0
Okay
3,287 reviews
Delta
8.0
Very good
7,934 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Ohio to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Ohio?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson (TYS) is the airport most travelers will use when flying to Knoxville from Ohio.

  • What are the cheapest airlines to fly from Ohio to Knoxville one-way?

    The cheapest airlines for a one-way flight from Ohio to Knoxville are Frontier ($116), Delta ($130), and American Airlines ($150).

  • What are the most popular routes from Ohio to Knoxville?

    Most travelers choose Detroit Metropolitan Wayne County - Knoxville McGhee Tyson, Cleveland Hopkins Intl - Knoxville McGhee Tyson or Pittsburgh - Knoxville McGhee Tyson when deciding on the best route from Ohio to Knoxville.

  • Can I find deals for flights from Ohio to Knoxville that include hotel bookings?

    Yes. In addition to deals on Ohio to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ohio to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to Knoxville.

  • Can I find deals for business class flights from Ohio to Knoxville?

    Yes. Cheapflights offers flight deals from Ohio to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Ohio to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Ohio to Knoxville (average of $296). Flying from Ohio to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Ohio?

Book flights to Ohio if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Maryville
Oak Ridge
Alcoa
Murphy

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Alternative routes for Ohio to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Ohio to Knoxville

Discover the top 3 airlines that operate flights from Ohio to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$198Average$275FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$198Average$317FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$204Average$302FlexibilityNo cancel feeOn-time71%

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