Knoxville

$260+ Cheap flights from Melbourne, FL to Knoxville (MLB - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/18. Fares are subject to change and may not be available on all flights or dates of travel.
MLB — TYS
Oct 11 — Oct 181
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Cheap flight deals from Melbourne to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Melbourne (MLB) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$341
(Delta)

One-way from

$260
(American Airlines)

Popular in

October

Cheapest in

April

Average price

$388
From Melbourne to Knoxville McGhee Tyson
One-way flight from Melbourne to Knoxville McGhee Tyson
Highest demand for flights based on searches. 7% potential increase in price ($32 potential increase over avg. RT price).
Cheapest flight prices on average. 6% potential price decrease ($25 potential savings vs. average RT price).
Average for round-trip flights in September 2025

Find flight deals from Melbourne to Knoxville

Cheapest flights from Melbourne to Knoxville
Explore the most affordable flight options available from Melbourne to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/286:50 pmMLB - TYS
1 stop4h 17mDelta
Tue 11/45:44 amTYS - MLB
1 stop4h 42mDelta
Deal found 9/11$295
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/282:45 pmMLB - TYS
2 stops8h 54mAmerican Airlines
Tue 11/412:46 pmTYS - MLB
1 stop4h 05mAmerican Airlines
Deal found 9/11$300
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/166:50 pmMLB - TYS
1 stop4h 56mDelta
Tue 10/217:11 amTYS - MLB
1 stop3h 15mDelta
Deal found 9/9$341
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/132:28 pmMLB - TYS
1 stop4h 31mDelta
Tue 12/165:25 amTYS - MLB
1 stop5h 11mDelta
Deal found 9/11$357
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2312:56 pmMLB - TYS
1 stop5h 54mAmerican Airlines
Tue 9/308:23 amTYS - MLB
1 stop3h 54mAmerican Airlines
Deal found 9/10$361
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/167:11 pmMLB - TYS
1 stop4h 42mAmerican Airlines
Tue 10/216:03 amTYS - MLB
2 stops16h 55mAmerican Airlines
Deal found 9/9$381
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1211:21 amMLB - TYS
1 stop3h 30mDelta
Mon 12/155:25 amTYS - MLB
1 stop5h 11mDelta
Deal found 9/11$387
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/267:11 pmMLB - TYS
1 stop4h 39mAmerican Airlines
Fri 10/314:41 pmTYS - MLB
2 stops20h 31mAmerican Airlines
Deal found 9/10$391
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/255:35 pmMLB - TYS
1 stop6h 32mAmerican Airlines
Mon 9/295:05 amTYS - MLB
1 stop7h 12mAmerican Airlines
Deal found 9/10$463

Cheapflights Fare Finder

 
Customize your flight search to find flights from Melbourne to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Melbourne to Knoxville that are best for you.

Fly from

Melbourne

Fly to

Knoxville

Route

Depart

Return

Price

MelbourneKnoxville

MLB - TYS

MLBTYS

Melbourne

Tue 10/28

6:50 pm-11:07 pm

1 stop4h 17m

Knoxville McGhee Tyson

Tue 11/4

5:44 am-10:26 am

1 stop4h 42m

$295

MelbourneKnoxville

MLB - TYS

MLBTYS

Melbourne

Thu 10/16

6:50 pm-11:46 pm

1 stop4h 56m

Knoxville McGhee Tyson

Tue 10/21

7:11 am-10:26 am

1 stop3h 15m

$341

MelbourneKnoxville

MLB - TYS

MLBTYS

Melbourne

Sat 12/13

2:28 pm-6:59 pm

1 stop4h 31m

Knoxville McGhee Tyson

Tue 12/16

5:25 am-10:36 am

1 stop5h 11m

$357

MelbourneKnoxville

MLB - TYS

MLBTYS

Melbourne

Tue 9/23

12:56 pm-6:50 pm

1 stop5h 54m

Knoxville McGhee Tyson

Tue 9/30

8:23 am-12:17 pm

1 stop3h 54m

$361

MelbourneKnoxville

MLB - TYS

MLBTYS

Melbourne

Wed 12/10

2:28 pm-6:59 pm

1 stop4h 31m

Knoxville McGhee Tyson

Sun 12/14

5:25 am-10:36 am

1 stop5h 11m

$361

MelbourneKnoxville

MLB - TYS

MLBTYS

Melbourne

Thu 10/16

7:11 pm-11:53 pm

1 stop4h 42m

Knoxville McGhee Tyson

Tue 10/21

6:03 am-10:58 pm

2 stops16h 55m

$381

MelbourneKnoxville

MLB - TYS

MLBTYS

Melbourne

Fri 12/12

11:21 am-2:51 pm

1 stop3h 30m

Knoxville McGhee Tyson

Mon 12/15

5:25 am-10:36 am

1 stop5h 11m

$387

MelbourneKnoxville

MLB - TYS

MLBTYS

Melbourne

Thu 9/25

5:35 pm-12:07 am

1 stop6h 32m

Knoxville McGhee Tyson

Mon 9/29

5:05 am-12:17 pm

1 stop7h 12m

$463

MelbourneKnoxville

MLB - TYS

MLBTYS

Melbourne

Mon 9/22

12:56 pm-7:05 pm

1 stop6h 09m

Knoxville McGhee Tyson

Mon 9/29

5:05 am-12:17 pm

1 stop7h 12m

$505

MelbourneKnoxville

MLB - TYS

MLBTYS

Melbourne

Sat 10/18

8:21 am-9:03 pm

2 stops12h 42m

$371

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Best time to book a flight from Melbourne to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Melbourne with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Melbourne to Knoxville

What is the cheapest month to book a flight from Melbourne, Florida to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Melbourne, Florida to Knoxville (average of $294). Flying from Melbourne, Florida to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MLB to TYS?

Find hourly flight availability from Melbourne to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 40% on flights from Melbourne, Florida to Knoxville by exploring options for tickets at noon.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated September 11, 2025.
Get a feel of what it's like to fly with Delta and American Airlines from Melbourne to Knoxville by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
8.0
Very good

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
8.0
Very good
8.0
Very good

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
8.0
Very good

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Melbourne to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Melbourne, Florida to Knoxville?

    Departing from Melbourne, Florida to Knoxville will take you 4h 17m. Melbourne, Florida and Knoxville are separated by a distance of 567 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Melbourne, Florida to Knoxville round-trip?

    Flying on American Airlines is currently your cheapest option to Knoxville, with prices starting at $268. Another option worth looking into is Delta, starting at $279 round trip. American Airlines is priced at 36% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Melbourne to Knoxville that include hotel bookings?

    Yes. In addition to deals on Melbourne to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Melbourne to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Melbourne to Knoxville.

  • Can I find deals for business class flights from Melbourne to Knoxville?

    Yes. Cheapflights offers flight deals from Melbourne to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Melbourne, Florida to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Melbourne, Florida to Knoxville (average of $294). Flying from Melbourne, Florida to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

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Alternative routes for Melbourne to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Melbourne to Knoxville

Discover the top 2 airlines that operate flights from Melbourne to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$268Average$419FlexibilityNo cancel feeOn-time71%
DeltaCheapest$279Average$428FlexibilityNo cancel feeOn-timeN/A

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