HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Knoxville

$249+ Cheap flights from Manchester, NH to Knoxville (MHT - TYS)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/20. Fares are subject to change and may not be available on all flights or dates of travel.
MHT — TYS
Aug 2 — Aug 91
Sat 8/2
Sat 8/9
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Manchester to Knoxville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Manchester to Knoxville McGhee Tyson are usually found in August or June, booked 48 days in advance, depart on a Saturday or Monday and return on a Tuesday

Cheap flight deals from Manchester to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MHT) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 28, 2025.

Round-trip from

$249
(American Airlines)

Popular in

March

Cheapest in

August

Average price

$448
From Manchester to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($52 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($21 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2025
Search Deals

Find flight deals from Manchester to Knoxville

Cheapest flights from Manchester to Knoxville
Explore the most affordable flight options available from Manchester to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 28, 2025.

This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/207:04 amMHT - TYS
1 stop7h 30mAmerican Airlines
Mon 8/255:12 pmTYS - MHT
1 stop6h 28mAmerican Airlines
Deal found 7/27$249
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/211:30 pmMHT - TYS
2 stops9h 07mUnited Airlines
Sun 8/245:45 amTYS - MHT
1 stop4h 57mUnited Airlines
Deal found 7/28$276

Cheapflights Fare Finder

 
Customize your flight search to find flights from Manchester to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 28, 2025.
Use the filters below to find and compare flights from Manchester to Knoxville that are best for you.

Fly from

Manchester

Fly to

Knoxville

Route

Depart

Return

Price

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Wed 8/20

7:04 am-2:34 pm

1 stop7h 30m

Knoxville McGhee Tyson

Mon 8/25

5:12 pm-11:40 pm

1 stop6h 28m

$249

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Thu 8/21

1:30 pm-10:37 pm

2 stops9h 07m

Knoxville McGhee Tyson

Sun 8/24

5:45 am-10:42 am

1 stop4h 57m

$276

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Sun 8/3

7:00 am-12:34 pm

1 stop5h 34m

$403

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Sun 8/3

6:25 pm-7:40 am

2 stops13h 15m

$425

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Sun 8/3

6:45 pm-10:35 pm

3 stops27h 50m

$2,113

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/28

Best time to book a flight from Manchester to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Manchester with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Knoxville

How far ahead should I book a flight from Manchester, New Hampshire to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from Manchester to Knoxville. Price data was last updated on July 25, 2025.

The best time to book flights from Manchester, New Hampshire to Knoxville is 48 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Manchester, New Hampshire to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Manchester, New Hampshire to Knoxville (average of $295). Flying from Manchester, New Hampshire to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MHT to TYS?

Find hourly flight availability from Manchester to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 28, 2025.

One of the essential ways to save on airfare from Manchester, New Hampshire to Knoxville is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the evening could potentially save you up to 25% on airfare.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated July 28, 2025.
Read reviews from past customers who have flown United Airlines and American Airlines from Manchester to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,893 reviews

Comfort

7.3

Boarding

7.7

Entertainment

7.1

Crew

8.1

Overall

7.4

Food

6.6

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
United Airlines
7.4
Good
8,893 reviews
United Airlines
7.4
Good
8,893 reviews

Comfort

7.3

Boarding

7.7

Entertainment

7.1

Crew

8.1

Overall

7.4

Food

6.6

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,893 reviews

Comfort

7.3

Boarding

7.7

Entertainment

7.1

Crew

8.1

Overall

7.4

Food

6.6

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!

Related info for your journey

Find useful and relevant information for your journey from Manchester to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Manchester, New Hampshire to Knoxville round-trip?

    Cheapflights users have booked flights from Manchester, New Hampshire to Knoxville round-trip from $249. Another airline that can offer you cheap pricing is United Airlines. These flights start at 52% lower than the current average price 3 months from now.

  • Can I find deals for flights from Manchester to Knoxville that include hotel bookings?

    Yes. In addition to deals on Manchester to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Knoxville.

  • Can I find deals for business class flights from Manchester to Knoxville?

    Yes. Cheapflights offers flight deals from Manchester to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester, New Hampshire to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Manchester, New Hampshire to Knoxville (average of $295). Flying from Manchester, New Hampshire to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Corbin
Cherokee
Alcoa
Oak Ridge
Murphy

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 2 airlines flying from Manchester to Knoxville

Discover the top 2 airlines that operate flights from Manchester to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$248Average$372FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$300Average$556FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.