How long is the flight from Manchester, New Hampshire to Knoxville?

Departing from Manchester, New Hampshire to Knoxville will take you 5h 12m. Airlines will cover a distance of 830 mi.

What are the cheapest airlines flying from Manchester, New Hampshire to Knoxville round-trip?

Cheapflights users have booked flights from Manchester, New Hampshire to Knoxville round-trip from $248. Another airline that can offer you cheap pricing is United Airlines. These flights start at 51% lower than the current average price 3 months from now.

What is the cheapest day to fly from Manchester, New Hampshire to Knoxville?

Travelers seeking maximum savings on their Manchester, New Hampshire to Knoxville flight should consider departing on Saturday mornings when fares are most often at their lowest. Tuesday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

What is the cheapest day to fly round-trip from Manchester, New Hampshire to Knoxville?

It’s generally more expensive to depart on a Friday, if you have to leave on this day you can still search on Cheapflights to find great options that meet your needs.

What is the cheapest month to fly from Manchester, New Hampshire to Knoxville?

The best pricing can be found in the month of February. Prices to Knoxville from Manchester, New Hampshire average $309. You can even find prices in February for less than $309, as users have found deals to Knoxville from as low as $88. The month of January appears to be one of the more expensive times to travel to Knoxville from Manchester, New Hampshire. Flying in the targeted month can save you up to 83%.

Can I find deals for flights from Manchester to Knoxville that include hotel bookings?

Yes. In addition to deals on Manchester to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Manchester to Knoxville?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Knoxville.

Can I find deals for business class flights from Manchester to Knoxville?

Yes. Cheapflights offers flight deals from Manchester to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$203+ Cheap Flights from Manchester, NH to Knoxville

Q: How much does it cost to fly round-trip from Manchester, New Hampshire to Knoxville?

Airfare is below average for this route at the moment. Manchester, New Hampshire to Knoxville flights typically cost between $351 and $515 in November. The cheapest round-trip price found within the last 3 days was $203 on American Airlines (Nov 11-Nov 15).

Q: How far in advance should I book a flight from Manchester, New Hampshire to Knoxville?

When searching for a good deal, it’s best to be prepared for potential fluctuations in price. We recommend booking at least 47 days in advance, which can save you up to 131% on flights from Manchester, New Hampshire to Knoxville compared to booking the week you need them. Waiting 47 days out may not be for everyone, so we have options available for flights within the next two weeks, with the lowest price starting at $199. For sooner than that we have options available in the next 3 days from $382.

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Find cheap flights from Manchester to Knoxville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

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Cheapflights Tip: The best prices from Manchester to Knoxville McGhee Tyson are usually found in August or June, booked 44 days in advance, depart on a Saturday or Monday and return on a Tuesday

Cheap flight deals from Manchester to Knoxville

Round-trip from	$203 (American Airlines)
Popular in	March
Cheapest in	August
Average price	$413

From Manchester to Knoxville McGhee Tyson

Search Deals

Highest demand for flights based on searches. 10% potential increase in price ($60 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 4% potential price decrease ($23 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in September 2025

Search Deals

Find flight deals from Manchester to Knoxville

Cheapest flights from Manchester to Knoxville
Explore the most affordable flight options available from Manchester to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

Tue 11/116:00 amMHT - TYS

1 stop4h 52mAmerican Airlines

Sat 11/156:27 pmTYS - MHT

1 stop4h 30mAmerican Airlines

Deal found 9/10

$203

Sat 10/45:49 pmMHT - TYS

1 stop5h 14mAmerican Airlines

Thu 10/95:37 pmTYS - MHT

1 stop6h 19mAmerican Airlines

Deal found 9/10

$264

Wed 11/125:20 pmMHT - TYS

1 stop4h 09mAmerican Airlines

Sat 11/154:15 pmTYS - MHT

1 stop6h 36mAmerican Airlines

Deal found 9/10

$273

Sat 10/253:26 pmMHT - TYS

2 stops8h 24mAmerican Airlines

Wed 10/2910:00 amTYS - MHT

1 stop5h 00mAmerican Airlines

Deal found 9/9

$283

Fri 9/264:18 pmMHT - TYS

1 stop4h 32mAmerican Airlines

Tue 9/302:34 pmTYS - MHT

1 stop6h 23mAmerican Airlines

Deal found 9/11

$320

Tue 11/116:41 amMHT - TYS

1 stop5h 05mAmerican Airlines

Fri 11/146:06 amTYS - MHT

1 stop5h 33mAmerican Airlines

Deal found 9/10

$334

Best flights from Manchester to Knoxville
Discover carefully curated flight deals from Manchester to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 11, 2025.

Tue 11/114:05 pmMHT - TYS

1 stop5h 12mAmerican Airlines

Sat 11/154:15 pmTYS - MHT

1 stop6h 36mAmerican Airlines

Deal found 9/9

$203

Wed 10/19:40 amMHT - TYS

1 stop5h 05mUnited Airlines

Tue 10/79:55 amTYS - MHT

1 stop5h 07mUnited Airlines

Deal found 9/9

$273

Wed 11/1211:29 amMHT - TYS

1 stop4h 29mAmerican Airlines

Sat 11/154:15 pmTYS - MHT

1 stop6h 36mAmerican Airlines

Deal found 9/10

$273

Wed 11/129:30 amMHT - TYS

2 stops11h 03mUnited Airlines

Sat 11/151:52 pmTYS - MHT

2 stops9h 52mUnited Airlines

Deal found 9/10

$283

Fri 9/264:18 pmMHT - TYS

1 stop4h 32mAmerican Airlines

Tue 9/302:34 pmTYS - MHT

1 stop6h 23mAmerican Airlines

Deal found 9/11

$320

Last-minute flights from Manchester to Knoxville
Discover last-minute flight deals from Manchester to Knoxville. Data last updated September 11, 2025 and is based on user searches.

Fri 9/264:18 pmMHT - TYS

1 stop4h 32mAmerican Airlines

Tue 9/302:34 pmTYS - MHT

1 stop6h 23mAmerican Airlines

Deal found 9/11

$320

Tue 9/309:40 amMHT - TYS

1 stop5h 05mUnited Airlines

Tue 10/79:55 amTYS - MHT

1 stop5h 07mUnited Airlines

Deal found 9/9

$273

Tue 9/309:40 amMHT - TYS

1 stop5h 05mUnited Airlines

Wed 10/87:00 amTYS - MHT

2 stops8h 02mUnited Airlines

Deal found 9/9

$339

Thu 10/26:00 amMHT - TYS

1 stop4h 51mAmerican Airlines

Tue 10/75:37 pmTYS - MHT

1 stop6h 19mAmerican Airlines

Deal found 9/9

$334

Sat 10/45:49 pmMHT - TYS

1 stop5h 14mAmerican Airlines

Thu 10/95:37 pmTYS - MHT

1 stop6h 19mAmerican Airlines

Deal found 9/10

$264

Wed 10/155:15 pmMHT - TYS

1 stop4h 54mAmerican Airlines

Wed 10/226:10 pmTYS - MHT

1 stop4h 47mAmerican Airlines

Deal found 9/11

$340

Sat 10/185:45 amMHT - TYS

1 stop4h 28mAmerican Airlines

Sat 10/257:00 amTYS - MHT

1 stop4h 36mAmerican Airlines

Deal found 9/9

$353

Sat 10/253:26 pmMHT - TYS

2 stops8h 24mAmerican Airlines

Wed 10/2910:00 amTYS - MHT

1 stop5h 00mAmerican Airlines

Deal found 9/9

$283

One-way flights from Manchester to Knoxville
Search for one-way flight options from Manchester to Knoxville. Find affordable one-way fares based on user searches. Data last updated September 11, 2025.

Tue 10/219:40 amMHT - TYS

1 stop5h 05mUnited Airlines

Deal found 9/10

$259

Sun 9/213:59 pmMHT - TYS

1 stop5h 15mAmerican Airlines

Deal found 9/10

$289

Thu 10/239:40 amMHT - TYS

1 stop5h 05mUnited Airlines

Deal found 9/10

$320

Fri 10/109:40 amMHT - TYS

2 stops24h 30mUnited Airlines

Deal found 9/10

$477

Fri 11/72:27 pmMHT - TYS

1 stop20h 21mUnited Airlines

Deal found 9/8

$510

Sat 11/299:30 amMHT - TYS

1 stop14h 29mUnited Airlines

Deal found 9/9

$548

Mon 12/12:27 pmMHT - TYS

1 stop24h 16mUnited Airlines

Deal found 9/9

$587

Wed 10/229:40 amMHT - TYS

2 stops24h 30mUnited Airlines

Deal found 9/10

$700

Cheapflights Fare Finder

Use the filters below to find and compare flights from Manchester to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Tue 11/11

4:05 pm-9:17 pm

1 stop5h 12m

Knoxville McGhee Tyson

Sat 11/15

4:15 pm-10:51 pm

1 stop6h 36m

$203

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Wed 10/1

9:40 am-2:45 pm

1 stop5h 05m

Knoxville McGhee Tyson

Tue 10/7

9:55 am-3:02 pm

1 stop5h 07m

$273

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Wed 11/12

11:29 am-3:58 pm

1 stop4h 29m

Knoxville McGhee Tyson

Sat 11/15

4:15 pm-10:51 pm

1 stop6h 36m

$273

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Wed 11/12

9:30 am-8:33 pm

2 stops11h 03m

Knoxville McGhee Tyson

Sat 11/15

1:52 pm-11:44 pm

2 stops9h 52m

$283

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Fri 9/26

4:18 pm-8:50 pm

1 stop4h 32m

Knoxville McGhee Tyson

Tue 9/30

2:34 pm-8:57 pm

1 stop6h 23m

$320

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Wed 10/22

9:40 am-2:45 pm

1 stop5h 05m

$259

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Tue 10/21

9:40 am-2:45 pm

1 stop5h 05m

$259

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Sun 9/21

3:59 pm-9:14 pm

1 stop5h 15m

$289

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Fri 10/10

9:40 am-10:10 am

2 stops24h 30m

$477

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Fri 11/7

2:27 pm-10:48 am

1 stop20h 21m

$510

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 12 results

Best time to book a flight from Manchester to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Manchester with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Knoxville

How far ahead should I book a flight from Manchester, New Hampshire to Knoxville?

The best time to book flights from Manchester, New Hampshire to Knoxville is 42 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Manchester, New Hampshire to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Manchester, New Hampshire to Knoxville (average of $294). Flying from Manchester, New Hampshire to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MHT to TYS?

One of the essential ways to save on airfare from Manchester, New Hampshire to Knoxville is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the evening could potentially save you up to 25% on airfare.

How much does it cost to fly round-trip from Manchester, New Hampshire to Knoxville?

Reviews of airlines servicing Knoxville

Read reviews from past customers who have flown United Airlines and American Airlines from Manchester to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

United Airlines

7.4

Good

8,937 reviews

Reviews

1 / 20

2.0

Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!

United Airlines

7.4

Good

8,937 reviews

United Airlines

7.4

Good

8,937 reviews

Reviews

1 / 20

2.0

Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!

American Airlines

7.2

Good

10,000 reviews

United Airlines

7.4

Good

8,937 reviews

Reviews

1 / 20

2.0

Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!

Related info for your journey

How long is the flight from Manchester, New Hampshire to Knoxville?
Departing from Manchester, New Hampshire to Knoxville will take you 5h 12m. Airlines will cover a distance of 830 mi.
What are the cheapest airlines flying from Manchester, New Hampshire to Knoxville round-trip?
Cheapflights users have booked flights from Manchester, New Hampshire to Knoxville round-trip from $248. Another airline that can offer you cheap pricing is United Airlines. These flights start at 51% lower than the current average price 3 months from now.
Can I find deals for flights from Manchester to Knoxville that include hotel bookings?
Yes. In addition to deals on Manchester to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Manchester to Knoxville?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Knoxville.
Can I find deals for business class flights from Manchester to Knoxville?
Yes. Cheapflights offers flight deals from Manchester to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Manchester, New Hampshire to Knoxville?
Currently, January is the cheapest month in which you can book a flight from Manchester, New Hampshire to Knoxville (average of $294). Flying from Manchester, New Hampshire to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Morristown

Cherokee

Corbin

Alcoa

Oak Ridge

Murphy

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Other flights to Knoxville

Top 2 airlines flying from Manchester to Knoxville

Airline	Cheapest	Average	Flexibility	On-time
United Airlines	Cheapest$248	Average$371	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$248	Average$526	FlexibilityNo cancel fee	On-time71%

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$203+ Cheap flights from Manchester, NH to Knoxville (MHT - TYS)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/11. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Manchester to Knoxville with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Manchester to Knoxville McGhee Tyson are usually found in August or June, booked 44 days in advance, depart on a Saturday or Monday and return on a Tuesday

Cheap flight deals from Manchester to Knoxville

Round-trip from

Popular in

Cheapest in

Average price

Find flight deals from Manchester to Knoxville

Cheapest flights from Manchester to KnoxvilleExplore the most affordable flight options available from Manchester to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

Explore the most affordable flight options available from Manchester to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Manchester to Knoxville that are best for you.

Best time to book a flight from Manchester to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Manchester with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Knoxville

How far ahead should I book a flight from Manchester, New Hampshire to Knoxville?

What is the cheapest month to book a flight from Manchester, New Hampshire to Knoxville?

What is the cheapest time of day to fly from MHT to TYS?

How much does it cost to fly round-trip from Manchester, New Hampshire to Knoxville?

Reviews of airlines servicing Knoxville

Read reviews from past customers who have flown United Airlines and American Airlines from Manchester to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Manchester to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Manchester, New Hampshire to Knoxville?

What are the cheapest airlines flying from Manchester, New Hampshire to Knoxville round-trip?

Can I find deals for flights from Manchester to Knoxville that include hotel bookings?

How can I find direct flights from Manchester to Knoxville?

Can I find deals for business class flights from Manchester to Knoxville?

What is the cheapest month to book a flight from Manchester, New Hampshire to Knoxville?

Traveling to a place near Knoxville?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Manchester to Knoxville

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Top 2 airlines flying from Manchester to Knoxville

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Cheapest flights from Manchester to Knoxville
Explore the most affordable flight options available from Manchester to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.