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$179+ Cheap flights from Manchester, NH to Knoxville (MHT - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/31. Fares are subject to change and may not be available on all flights or dates of travel.
MHT — TYS
Nov 27 — Dec 41
Thu 11/27
Thu 12/4
1 adult, Economy
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Cheapflights Tip: The best prices from Manchester to Knoxville McGhee Tyson are usually found in August or February, booked 44 days in advance, depart on a Saturday or Monday and return on a Tuesday

Find flight deals from Manchester to Knoxville

Cheapest flights from Manchester to Knoxville
Explore the most affordable flight options available from Manchester to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 28, 2025.

This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/304:15 pmMHT - TYS
1 stop4h 28mAmerican Airlines
Fri 1/25:42 amTYS - MHT
1 stop5h 29mAmerican Airlines
Deal found 10/27$355
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/45:44 amMHT - TYS
1 stop4h 46mAmerican Airlines
Sun 12/77:00 amTYS - MHT
1 stop4h 07mAmerican Airlines
Deal found 10/28$357
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/156:00 amMHT - TYS
1 stop9h 47mAmerican Airlines
Tue 11/184:29 pmTYS - MHT
1 stop7h 29mAmerican Airlines
Deal found 10/28$377
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/216:00 amMHT - TYS
1 stop4h 52mAmerican Airlines
Sun 11/235:03 pmTYS - MHT
1 stop6h 55mAmerican Airlines
Deal found 10/28$397
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/84:40 pmMHT - TYS
1 stop6h 14mAmerican Airlines
Wed 11/126:05 amTYS - MHT
1 stop4h 58mAmerican Airlines
Deal found 10/27$427
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/109:30 amMHT - TYS
2 stops11h 03mUnited Airlines
Fri 11/149:50 amTYS - MHT
1 stop3h 57mUnited Airlines
Deal found 10/26$442
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2912:52 pmMHT - TYS
1 stop4h 14mAmerican Airlines
Sat 11/16:11 pmTYS - MHT
1 stop4h 54mAmerican Airlines
Deal found 10/28$447

Cheap flight deals from Manchester to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MHT) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$353
(American Airlines)

One-way from

$179
(American Airlines)

Popular in

March

Cheapest in

August

Average price

$476
Provider with most accurate pricing for Manchester-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Manchester-Knoxville McGhee Tyson flights.
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From Manchester to Knoxville McGhee Tyson
Search Deals
One-way flight from Manchester to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($40 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($24 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Manchester to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
Use the filters below to find and compare flights from Manchester to Knoxville that are best for you.

Fly from

Manchester

Fly to

Knoxville

Route

Depart

Return

Price

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Sat 1/17

1:48 pm-9:21 pm

1 stop7h 33m

Knoxville McGhee Tyson

Sat 1/24

6:05 am-1:17 pm

1 stop7h 12m

$353

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Tue 12/30

4:15 pm-8:43 pm

1 stop4h 28m

Knoxville McGhee Tyson

Fri 1/2

5:42 am-11:11 am

1 stop5h 29m

$355

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Mon 1/19

4:06 pm-8:56 pm

1 stop4h 50m

Knoxville McGhee Tyson

Fri 1/23

5:14 pm-11:56 pm

1 stop6h 42m

$357

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Thu 12/4

5:44 am-10:30 am

1 stop4h 46m

Knoxville McGhee Tyson

Sun 12/7

7:00 am-11:07 am

1 stop4h 07m

$357

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Mon 12/29

4:15 pm-8:43 pm

1 stop4h 28m

Knoxville McGhee Tyson

Fri 1/2

5:42 am-11:11 am

1 stop5h 29m

$357

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Sun 1/18

1:48 pm-9:21 pm

1 stop7h 33m

Knoxville McGhee Tyson

Fri 1/23

8:09 am-1:17 pm

1 stop5h 08m

$357

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Thu 2/12

10:57 am-3:45 pm

1 stop4h 48m

$179

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Fri 1/2

7:26 pm-11:59 pm

1 stop4h 33m

$214

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Tue 12/30

4:15 pm-8:43 pm

1 stop4h 28m

$214

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Thu 1/1

7:26 pm-11:59 pm

1 stop4h 33m

$214

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/27

Showing 1-10 of 17 results
1
2

Compare providers for flights from Manchester to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Manchester to Knoxville in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Manchester, New Hampshire-Knoxville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Manchester, New Hampshire-Knoxville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Manchester, New Hampshire-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Manchester, New Hampshire-Knoxville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Manchester, New Hampshire-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Manchester to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Manchester with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Knoxville

How far ahead should I book a flight from Manchester, New Hampshire to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from Manchester to Knoxville. Price data was last updated on October 24, 2025.

The best time to book flights from Manchester, New Hampshire to Knoxville is 42 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Manchester, New Hampshire to Knoxville?

Currently, May is the cheapest month in which you can book a flight from Manchester, New Hampshire to Knoxville (average of $54). Flying from Manchester, New Hampshire to Knoxville in January is currently the most expensive (average of $157). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MHT to TYS?

Find hourly flight availability from Manchester to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 28, 2025.

One of the essential ways to save on airfare from Manchester, New Hampshire to Knoxville is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the evening could potentially save you up to 25% on airfare.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated October 28, 2025.
Read reviews from past customers who have flown United Airlines and American Airlines from Manchester to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,001 reviews

Crew

8.1

Boarding

7.7

Overall

7.4

Comfort

7.3

Food

6.6

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
United Airlines
7.4
Good
9,001 reviews
United Airlines
7.4
Good
9,001 reviews

Crew

8.1

Boarding

7.7

Overall

7.4

Comfort

7.3

Food

6.6

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
American Airlines
7.2
Good
11,032 reviews
United Airlines
7.4
Good
9,001 reviews

Crew

8.1

Boarding

7.7

Overall

7.4

Comfort

7.3

Food

6.6

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

Related info for your journey

Find useful and relevant information for your journey from Manchester to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Manchester, New Hampshire to Knoxville?

    Departing from Manchester, New Hampshire to Knoxville will take you 7h 33m. Airlines will cover a distance of 830 mi.

  • What are the cheapest airlines flying from Manchester, New Hampshire to Knoxville round-trip?

    Cheapflights users have booked flights from Manchester, New Hampshire to Knoxville round-trip from $248. Another airline that can offer you cheap pricing is United Airlines. These flights start at 49% lower than the current average price 3 months from now.

  • Can I find deals for flights from Manchester to Knoxville that include hotel bookings?

    Yes. In addition to deals on Manchester to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Knoxville.

  • Can I find deals for business class flights from Manchester to Knoxville?

    Yes. Cheapflights offers flight deals from Manchester to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester, New Hampshire to Knoxville?

    Currently, May is the cheapest month in which you can book a flight from Manchester, New Hampshire to Knoxville (average of $54). Flying from Manchester, New Hampshire to Knoxville in January is currently the most expensive (average of $157). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Crossville
Corbin
Bryson City
Alcoa
Oak Ridge
Murphy

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Manchester to Knoxville

Discover the top 2 airlines that operate flights from Manchester to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$248Average$376FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$248Average$490FlexibilityNo cancel feeOn-time71%

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