$112+ Cheap flights from Portland, ME to Knoxville (PWM - TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/19. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — TYS
May 23 — May 301
Round-trip
1 adult, Economy
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Find cheap flights from Portland to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Portland to Knoxville
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Best
Last-minute
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Cheapest flights from Portland to KnoxvilleExplore the most affordable flight options available from Portland to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 23, 2026.
Explore the most affordable flight options available from Portland to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 23, 2026.
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/15:15 am
PWM
- TYS
1 stop5h 21m
United Airlines
Wed 9/27:19 pm
TYS
- PWM
1 stop4h 40m
United Airlines
Deal found 4/22![United Airlines logo]()
$303
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/59:52 am
PWM
- TYS
1 stop13h 47m
Multiple Airlines
Fri 6/127:22 pm
TYS
- PWM
1 stop13h 50m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$320
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/51:18 pm
PWM
- TYS
1 stop7h 32m
Delta
Fri 6/123:54 pm
TYS
- PWM
1 stop7h 21m
Delta
Deal found 4/21![Delta logo]()
$324
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/169:20 am
PWM
- TYS
1 stop5h 14m
United Airlines
Tue 5/197:18 pm
TYS
- PWM
1 stop4h 41m
United Airlines
Deal found 4/21![United Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/166:00 am
PWM
- TYS
1 stop5h 01m
American Airlines
Tue 5/196:38 pm
TYS
- PWM
1 stop4h 48m
American Airlines
Deal found 4/22![American Airlines logo]()
$338
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/226:00 am
PWM
- TYS
1 stop5h 01m
Delta
Sun 6/285:35 pm
TYS
- PWM
1 stop5h 54m
Delta
Deal found 4/20![Delta logo]()
$339
This Southwest deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/193:55 pm
PWM
- TYS
1 stop4h 55m
Southwest
Wed 5/2712:50 pm
TYS
- PWM
2 stops9h 45m
Southwest
Deal found 4/19![Southwest logo]()
$344
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/245:15 am
PWM
- TYS
2 stops8h 03m
United Airlines
Fri 5/297:19 pm
TYS
- PWM
1 stop4h 32m
United Airlines
Deal found 4/20![United Airlines logo]()
$354
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1710:30 am
PWM
- TYS
2 stops9h 50m
Southwest
Tue 6/2312:45 pm
TYS
- PWM
2 stops10h 10m
Southwest
Deal found 4/23![Southwest logo]()
$355
Best flights from Portland to KnoxvilleDiscover carefully curated flight deals from Portland to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 23, 2026.
Discover carefully curated flight deals from Portland to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 23, 2026.
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/15:15 am
PWM
- TYS
2 stops11h 44m
United Airlines
Wed 9/27:19 pm
TYS
- PWM
1 stop4h 40m
United Airlines
Deal found 4/22![United Airlines logo]()
$308
This Southwest deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/23:55 pm
PWM
- TYS
1 stop4h 55m
Southwest
Tue 6/98:10 am
TYS
- PWM
1 stop4h 15m
Southwest
Deal found 4/19![Southwest logo]()
$339
This Delta deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:00 am
PWM
- TYS
1 stop5h 50m
Delta
Sat 5/97:51 am
TYS
- PWM
1 stop4h 04m
Delta
Deal found 4/19![Delta logo]()
$389
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/169:20 am
PWM
- TYS
1 stop5h 14m
United Airlines
Tue 5/197:18 pm
TYS
- PWM
1 stop4h 41m
United Airlines
Deal found 4/21![United Airlines logo]()
$334
This Southwest deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:10 am
PWM
- TYS
2 stops11h 00m
Southwest
Wed 5/2712:50 pm
TYS
- PWM
2 stops9h 45m
Southwest
Deal found 4/19![Southwest logo]()
$349
This Southwest deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/165:40 am
PWM
- TYS
2 stops11h 15m
Southwest
Tue 5/1912:50 pm
TYS
- PWM
2 stops9h 45m
Southwest
Deal found 4/20![Southwest logo]()
$374
This Southwest deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/284:50 pm
PWM
- TYS
1 stop4h 25m
Southwest
Mon 6/112:15 pm
TYS
- PWM
2 stops11h 10m
Southwest
Deal found 4/19![Southwest logo]()
$382
Last-minute flights from Portland to KnoxvilleDiscover last-minute flight deals from Portland to Knoxville. Data last updated April 23, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to Knoxville. Data last updated April 23, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/81:18 pm
PWM
- TYS
1 stop7h 32m
Delta
Mon 5/115:59 pm
TYS
- PWM
1 stop5h 10m
Delta
Deal found 4/19![Delta logo]()
$364
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/159:52 am
PWM
- TYS
1 stop12h 32m
Multiple Airlines
Tue 5/193:48 pm
TYS
- PWM
2 stops24h 28m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$356
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/169:20 am
PWM
- TYS
1 stop5h 14m
United Airlines
Tue 5/197:18 pm
TYS
- PWM
1 stop4h 41m
United Airlines
Deal found 4/21![United Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/166:00 am
PWM
- TYS
1 stop5h 01m
American Airlines
Tue 5/196:38 pm
TYS
- PWM
1 stop4h 48m
American Airlines
Deal found 4/22![American Airlines logo]()
$338
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/169:52 am
PWM
- TYS
1 stop26h 32m
Multiple Airlines
Tue 5/193:48 pm
TYS
- PWM
2 stops25h 57m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$355
This Southwest deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/165:40 am
PWM
- TYS
2 stops11h 15m
Southwest
Tue 5/1912:50 pm
TYS
- PWM
2 stops9h 45m
Southwest
Deal found 4/20![Southwest logo]()
$374
This Southwest deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/193:55 pm
PWM
- TYS
1 stop4h 55m
Southwest
Wed 5/2712:50 pm
TYS
- PWM
2 stops9h 45m
Southwest
Deal found 4/19![Southwest logo]()
$344
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/217:56 pm
PWM
- TYS
2 stops38h 06m
Multiple Airlines
Thu 5/286:03 pm
TYS
- PWM
1 stop15h 09m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$361
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/245:15 am
PWM
- TYS
2 stops8h 03m
United Airlines
Fri 5/297:19 pm
TYS
- PWM
1 stop4h 32m
United Airlines
Deal found 4/20![United Airlines logo]()
$354
This Delta deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:50 pm
PWM
- TYS
1 stop4h 37m
Delta
Mon 6/15:59 pm
TYS
- PWM
1 stop5h 10m
Delta
Deal found 4/19![Delta logo]()
$339
One-way flights from Portland to KnoxvilleSearch for one-way flight options from Portland to Knoxville. Find affordable one-way fares based on user searches. Data last updated April 23, 2026.
Search for one-way flight options from Portland to Knoxville. Find affordable one-way fares based on user searches. Data last updated April 23, 2026.
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:02 am
PWM
- TYS
1 stop5h 02m
Delta
Deal found 4/21![Delta logo]()
$112
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/131:35 pm
PWM
- TYS
1 stop4h 42m
Delta
Deal found 4/20![Delta logo]()
$134
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:00 am
PWM
- TYS
1 stop5h 01m
American Airlines
Deal found 4/20![American Airlines logo]()
$170
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:10 am
PWM
- TYS
2 stops11h 00m
Southwest
Deal found 4/21![Southwest logo]()
$175
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/195:30 am
PWM
- TYS
2 stops11h 38m
United Airlines
Deal found 4/21![United Airlines logo]()
$197
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/165:40 am
PWM
- TYS
2 stops11h 15m
Southwest
Deal found 4/21![Southwest logo]()
$214
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:27 am
PWM
- TYS
1 stop7h 44m
American Airlines
Deal found 4/23![American Airlines logo]()
$219
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/135:15 am
PWM
- TYS
1 stop5h 21m
United Airlines
Deal found 4/22![United Airlines logo]()
$229
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3011:01 am
PWM
- TYS
3 stops55h 02m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$232
Find flight deals from Portland to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Portland (PWM) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $303 (United Airlines) |
One-way from | $112 (Delta) |
Popular in | December |
Cheapest in | January |
Average price | $525 |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 23, 2026.
Use the filters below to find and compare flights from Portland to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandKnoxville
PWM - TYS
PWMTYS
Portland
Tue 9/1
5:15 am-4:59 pm
2 stops11h 44m
Knoxville McGhee Tyson
Wed 9/2
7:19 pm-11:59 pm
1 stop4h 40m
$308
PortlandKnoxville
PWM - TYS
PWMTYS
Portland
Sat 5/16
9:20 am-2:34 pm
1 stop5h 14m
Knoxville McGhee Tyson
Tue 5/19
7:18 pm-11:59 pm
1 stop4h 41m
$334
Quickest round-trip
PortlandKnoxville
PWM - TYS
PWMTYS
Portland
Tue 6/2
3:55 pm-8:50 pm
1 stop4h 55m
Knoxville McGhee Tyson
Tue 6/9
8:10 am-12:25 pm
1 stop4h 15m
$339
PortlandKnoxville
PWM - TYS
PWMTYS
Portland
Tue 5/19
6:10 am-5:10 pm
2 stops11h 00m
Knoxville McGhee Tyson
Wed 5/27
12:50 pm-10:35 pm
2 stops9h 45m
$349
PortlandKnoxville
PWM - TYS
PWMTYS
Portland
Sat 5/16
5:40 am-4:55 pm
2 stops11h 15m
Knoxville McGhee Tyson
Tue 5/19
12:50 pm-10:35 pm
2 stops9h 45m
$374
PortlandKnoxville
PWM - TYS
PWMTYS
Portland
Thu 5/28
4:50 pm-9:15 pm
1 stop4h 25m
Knoxville McGhee Tyson
Mon 6/1
12:15 pm-11:25 pm
2 stops11h 10m
$382
PortlandKnoxville
PWM - TYS
PWMTYS
Portland
Tue 5/5
6:00 am-11:50 am
1 stop5h 50m
Knoxville McGhee Tyson
Sat 5/9
7:51 am-11:55 am
1 stop4h 04m
$389
Cheapest one-way
PortlandKnoxville
PWM - TYS
PWMTYS
Portland
Tue 5/19
6:00 am-11:09 am
1 stop5h 09m
$112
PortlandKnoxville
PWM - TYS
PWMTYS
Portland
Wed 5/20
6:00 am-1:10 pm
1 stop7h 10m
$112
Quickest one-way
PortlandKnoxville
PWM - TYS
PWMTYS
Portland
Thu 8/13
1:35 pm-6:17 pm
1 stop4h 42m
$134
Showing 1-10 of 16 resultsSorted by cheapest first
Compare providers for flights from Portland to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to Knoxville in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Portland, Maine-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland, Maine-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland, Maine-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Portland, Maine-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland, Maine-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Portland to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Portland with our price prediction graph.
PWM-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to Knoxville
What is the cheapest month to book a flight from Portland, Maine to Knoxville?
Currently, January is the cheapest month in which you can book a flight from Portland, Maine to Knoxville (average of $285). Flying from Portland, Maine to Knoxville in December is currently the most expensive (average of $724). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Portland, Maine to Knoxville?
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated April 23, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from Portland to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Entertainment
7.5
Food
7.0
Comfort
8.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Entertainment
7.5
Food
7.0
Comfort
8.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Entertainment
7.5
Food
7.0
Comfort
8.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Entertainment
7.5
Food
7.0
Comfort
8.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Entertainment
7.5
Food
7.0
Comfort
8.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Portland to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Alcoa
Murphy
Oak Ridge
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Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 23, 2026.
Portland and Knoxville flights
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Top 4 airlines flying from Portland to Knoxville
Discover the top 4 airlines that operate flights from Portland to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$258 | Average$368 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$258 | Average$348 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$278 | Average$476 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$293 | Average$413 | FlexibilityNo cancel fee | On-time63% |