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$160+ Cheap flights from Knoxville to Portland, ME (TYS - PWM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/24. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — PWM
Apr 13 — Apr 201
Mon 4/13
Mon 4/20
1 adult, Economy
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Cheap flight deals from Knoxville to Portland

Cheapest flights from Knoxville to Portland
Explore the most affordable flight options available from Knoxville to Portland. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 14, 2026.

This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/78:15 am
TYS
-
PWM
1 stop4h 05m
Southwest
Tue 4/143:55 pm
PWM
-
TYS
1 stop4h 55m
Southwest
Deal found 3/10$295
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:15 am
TYS
-
PWM
1 stop6h 07m
American Airlines
Sat 9/267:20 pm
PWM
-
TYS
1 stop4h 50m
American Airlines
Deal found 3/10$299
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:09 pm
TYS
-
PWM
1 stop6h 32m
American Airlines
Sat 10/32:54 pm
PWM
-
TYS
1 stop4h 10m
American Airlines
Deal found 3/10$319
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:20 pm
TYS
-
PWM
1 stop6h 15m
American Airlines
Mon 6/297:58 am
PWM
-
TYS
1 stop5h 15m
American Airlines
Deal found 3/10$339
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/137:19 pm
TYS
-
PWM
1 stop4h 32m
United Airlines
Fri 6/197:16 pm
PWM
-
TYS
1 stop4h 38m
United Airlines
Deal found 3/12$344
This Southwest deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/98:10 am
TYS
-
PWM
1 stop4h 15m
Southwest
Mon 6/153:10 pm
PWM
-
TYS
1 stop7h 10m
Southwest
Deal found 3/13$348
This Southwest deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/112:15 pm
TYS
-
PWM
2 stops11h 10m
Southwest
Fri 6/53:10 pm
PWM
-
TYS
1 stop7h 10m
Southwest
Deal found 3/13$349

Find flight deals from Knoxville to Portland

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Portland (PWM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 14, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$295
(Southwest)

One-way from

$160
(Delta)

Popular in

November

Cheapest in

September

Average price

$592
Provider with most accurate pricing for Knoxville McGhee Tyson-Portland flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Portland flights.
Search Deals
From Knoxville McGhee Tyson to Portland
Search Deals
One-way flight from Knoxville McGhee Tyson to Portland
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($44 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($22 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Portland that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 14, 2026.
Use the filters below to find and compare flights from Knoxville to Portland that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvillePortland

TYS - PWM

TYSPWM

Knoxville McGhee Tyson

Fri 4/10

6:35 am-4:15 pm

2 stops9h 40m

Portland

Sun 4/12

4:20 pm-9:05 pm

1 stop4h 45m

$354

KnoxvillePortland

TYS - PWM

TYSPWM

Knoxville McGhee Tyson

Tue 3/24

7:50 am-3:55 pm

1 stop8h 05m

Portland

Sat 3/28

5:20 pm-10:10 pm

1 stop4h 50m

$354

KnoxvillePortland

TYS - PWM

TYSPWM

Knoxville McGhee Tyson

Tue 4/7

7:00 am-2:20 pm

1 stop7h 20m

Portland

Wed 4/8

4:28 pm-11:08 pm

1 stop6h 40m

$365

KnoxvillePortland

TYS - PWM

TYSPWM

Knoxville McGhee Tyson

Wed 3/25

6:05 am-11:04 am

1 stop4h 59m

Portland

Sat 4/4

5:23 am-1:24 pm

1 stop8h 01m

$369
Quickest round-trip

KnoxvillePortland

TYS - PWM

TYSPWM

Knoxville McGhee Tyson

Fri 3/27

7:50 am-11:55 am

1 stop4h 05m

Portland

Tue 3/31

4:30 pm-9:10 pm

1 stop4h 40m

$369

KnoxvillePortland

TYS - PWM

TYSPWM

Knoxville McGhee Tyson

Thu 6/4

6:40 am-2:30 pm

1 stop7h 50m

Portland

Thu 6/4

5:20 pm-10:20 pm

1 stop5h 00m

$423
Cheapest one-way
Quickest one-way

KnoxvillePortland

TYS - PWM

TYSPWM

Knoxville McGhee Tyson

Sat 5/9

7:45 am-11:55 am

1 stop4h 10m

$160

KnoxvillePortland

TYS - PWM

TYSPWM

Knoxville McGhee Tyson

Sun 5/24

6:00 am-10:17 am

1 stop4h 17m

$160

KnoxvillePortland

TYS - PWM

TYSPWM

Knoxville McGhee Tyson

Sat 6/6

7:19 pm-11:51 pm

1 stop4h 32m

$170

KnoxvillePortland

TYS - PWM

TYSPWM

Knoxville McGhee Tyson

Sun 7/26

7:19 pm-11:51 pm

1 stop4h 32m

$193

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/10

Showing 1-10 of 15 resultsSorted by cheapest first
1
2

Compare providers for flights from Knoxville to Portland

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Portland in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Portland, Maine flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Portland, Maine flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Portland, Maine flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Portland, Maine flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Portland, Maine flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Portland

Have a flexible travel schedule? Discover the best time to fly to Portland from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Portland

What is the cheapest month to book a flight from Knoxville to Portland, Maine?

Currently, July is the cheapest month in which you can book a flight from Knoxville to Portland, Maine (average of $63). Flying from Knoxville to Portland, Maine in January is currently the most expensive (average of $186). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Portland

Get insights into the airlines that provide service to Portland. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Portland. Reviews last updated March 14, 2026.
Read reviews from past customers who have flown Delta,United Airlines, andAmerican Airlines from Knoxville to Portland. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,293 reviews

Crew

8.5

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Overall

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,293 reviews
Delta
7.9
Good
8,293 reviews

Crew

8.5

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Overall

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,427 reviews
Delta
7.9
Good
8,293 reviews

Crew

8.5

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Overall

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,472 reviews
Delta
7.9
Good
8,293 reviews

Crew

8.5

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Overall

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Portland. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Portland, Maine?

    There are many flights that can get you from Knoxville to Portland, Maine in 7h 20m. Fly via Southwest or United Airlines to get the fastest option. The distance from Knoxville to Portland, Maine is about 904 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Knoxville to Portland, Maine round-trip?

    Cheapflights users have booked flights from Knoxville to Portland, Maine round-trip from $258. Other airlines that can offer you cheap pricing are United Airlines, from $258, and Delta, from $258. American Airlines is 38% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Knoxville to Portland that include hotel bookings?

    Yes. In addition to deals on Knoxville to Portland flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Portland?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Portland.

  • Can I find deals for business class flights from Knoxville to Portland?

    Yes. Cheapflights offers flight deals from Knoxville to Portland by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Portland, Maine?

    Currently, July is the cheapest month in which you can book a flight from Knoxville to Portland, Maine (average of $63). Flying from Knoxville to Portland, Maine in January is currently the most expensive (average of $186). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Portland?

Book flights to Portland if you plan to visit one of these locations
North Conway
Brunswick
Auburn
Lewiston
Conway

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Top 4 airlines flying from Knoxville to Portland

Discover the top 4 airlines that operate flights from Knoxville to Portland. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 14, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$258Average$389FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$258Average$385FlexibilityNo cancel feeOn-time71%
DeltaCheapest$258Average$418FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$278Average$328FlexibilityNo cancel feeOn-time63%

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