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$165+ Cheap flights from Knoxville to Manchester, NH (TYS - MHT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/23. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MHT
Jul 8 — Jul 151
Tue 7/8
Tue 7/15
1 adult, Economy
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Cheap flight deals from Knoxville to Manchester

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Manchester (MHT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 3, 2025.

Round-trip from

$259
(American Airlines)

One-way from

$165
(American Airlines)

Popular in

December

Cheapest in

June

Average price

$459
From Knoxville McGhee Tyson to Manchester
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One-way flight from Knoxville McGhee Tyson to Manchester
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Highest demand for flights based on searches. 21% potential increase in price ($153 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($29 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Knoxville to Manchester

Cheapest flights from Knoxville to Manchester
Explore the most affordable flight options available from Knoxville to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/176:34 amTYS - MHT
1 stop6h 28mAmerican Airlines
Mon 7/211:32 pmMHT - TYS
1 stop4h 07mAmerican Airlines
Deal found 7/2$259
This United Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/175:45 amTYS - MHT
1 stop4h 59mUnited Airlines
Mon 7/216:45 pmMHT - TYS
1 stop5h 14mUnited Airlines
Deal found 7/2$354
This Mytrip deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/96:12 pmTYS - MHT
2 stops23h 33mMultiple Airlines
Wed 7/166:44 pmMHT - TYS
2 stops25h 20mMultiple Airlines
Deal found 7/3$660

Cheapflights Fare Finder

Customize your flight search to find flights from Knoxville to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
Use the filters below to find and compare flights from Knoxville to Manchester that are best for you.

Fly from

Knoxville

Fly to

Manchester

Route

Depart

Return

Price

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

Thu 7/17

6:34 am-1:02 pm

1 stop6h 28m

Manchester

Mon 7/21

1:32 pm-5:39 pm

1 stop4h 07m

$259

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

Thu 7/17

5:45 am-10:44 am

1 stop4h 59m

Manchester

Mon 7/21

6:45 pm-11:59 pm

1 stop5h 14m

$354

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

Tue 9/23

5:20 pm-11:41 pm

1 stop6h 21m

$165

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

Wed 7/16

7:10 am-6:04 pm

2 stops10h 54m

$234

KnoxvilleManchester

TYS - MHT

TYSMHT

Knoxville McGhee Tyson

Wed 7/16

9:55 am-2:59 pm

1 stop5h 04m

$285

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/2

Best time to book a flight from Knoxville to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Manchester

What is the cheapest month to book a flight from Knoxville to Manchester, New Hampshire?

Currently, January is the cheapest month in which you can book a flight from Knoxville to Manchester, New Hampshire (average of $334). Flying from Knoxville to Manchester, New Hampshire in April is currently the most expensive (average of $396). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Knoxville to Manchester, New Hampshire?

Reviews of airlines servicing Manchester

Get insights into the airlines that provide service to Manchester. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Manchester. Reviews last updated July 3, 2025.
Read through reviews of airlines operating flights from Knoxville to Manchester, such as United Airlines and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,861 reviews

Entertainment

7.0

Crew

8.1

Food

6.6

Comfort

7.3

Boarding

7.7

Overall

7.4

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
United Airlines
7.4
Good
8,861 reviews
United Airlines
7.4
Good
8,861 reviews

Entertainment

7.0

Crew

8.1

Food

6.6

Comfort

7.3

Boarding

7.7

Overall

7.4

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,861 reviews

Entertainment

7.0

Crew

8.1

Food

6.6

Comfort

7.3

Boarding

7.7

Overall

7.4

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Knoxville to Manchester, New Hampshire round-trip?

    Flying on American Airlines is currently your cheapest option to Manchester, New Hampshire, with prices starting at $259. Another option worth looking into is United Airlines, starting at $354 round trip. American Airlines is 53% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Knoxville to Manchester that include hotel bookings?

    Yes. In addition to deals on Knoxville to Manchester flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Manchester.

  • Can I find deals for business class flights from Knoxville to Manchester?

    Yes. Cheapflights offers flight deals from Knoxville to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Manchester, New Hampshire?

    Currently, January is the cheapest month in which you can book a flight from Knoxville to Manchester, New Hampshire (average of $334). Flying from Knoxville to Manchester, New Hampshire in April is currently the most expensive (average of $396). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

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Keene

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Top 2 airlines flying from Knoxville to Manchester

Discover the top 2 airlines that operate flights from Knoxville to Manchester. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$250Average$334FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$314Average$564FlexibilityNo cancel feeOn-time71%

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