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Knoxville

$166+ Cheap flights from Manchester, NH to Knoxville (MHT - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/12. Fares are subject to change and may not be available on all flights or dates of travel.
MHT — TYS
Jun 16 — Jun 231
Tue 6/16
Tue 6/23
1 adult, Economy
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Cheap flight deals from Manchester to Knoxville

Cheapest flights from Manchester to Knoxville
Explore the most affordable flight options available from Manchester to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 17, 2026.

This Southwest deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/93:55 pm
MHT
-
TYS
1 stop5h 20m
Southwest
Tue 6/168:10 am
TYS
-
MHT
1 stop4h 15m
Southwest
Deal found 5/13$331
This Southwest deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/85:10 pm
MHT
-
TYS
1 stop5h 20m
Southwest
Wed 6/108:10 am
TYS
-
MHT
2 stops8h 05m
Southwest
Deal found 5/13$346
This American Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2210:06 am
MHT
-
TYS
1 stop7h 29m
American Airlines
Sat 8/297:00 am
TYS
-
MHT
1 stop4h 31m
American Airlines
Deal found 5/14$351
This Southwest deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:40 am
MHT
-
TYS
2 stops11h 30m
Southwest
Mon 8/312:05 pm
TYS
-
MHT
2 stops8h 20m
Southwest
Deal found 5/14$361
This Southwest deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/66:30 am
MHT
-
TYS
1 stop10h 40m
Southwest
Mon 8/1012:30 pm
TYS
-
MHT
1 stop9h 20m
Southwest
Deal found 5/15$362
This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/65:38 am
MHT
-
TYS
1 stop4h 58m
American Airlines
Sat 6/137:03 pm
TYS
-
MHT
1 stop4h 36m
American Airlines
Deal found 5/13$364
This Southwest deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/115:10 pm
MHT
-
TYS
1 stop5h 20m
Southwest
Wed 6/178:10 am
TYS
-
MHT
1 stop4h 15m
Southwest
Deal found 5/13$374
This Southwest deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:15 am
MHT
-
TYS
1 stop10h 30m
Southwest
Sun 10/2512:35 pm
TYS
-
MHT
1 stop9h 10m
Southwest
Deal found 5/13$375

Find flight deals from Manchester to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MHT) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 17, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$331
(Southwest)

One-way from

$166
(American Airlines)

Popular in

December

Cheapest in

August

Average price

$412
Provider with most accurate pricing for Manchester-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Manchester-Knoxville McGhee Tyson flights.
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From Manchester to Knoxville McGhee Tyson
Search Deals
One-way flight from Manchester to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($35 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Manchester to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 17, 2026.
Use the filters below to find and compare flights from Manchester to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Tue 6/9

6:55 am-5:00 pm

2 stops10h 05m

Knoxville McGhee Tyson

Wed 6/10

8:10 am-4:15 pm

2 stops8h 05m

$341

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Sat 9/19

3:00 pm-7:20 pm

1 stop4h 20m

Knoxville McGhee Tyson

Sat 9/26

7:50 am-2:55 pm

1 stop7h 05m

$351

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Thu 8/6

6:30 am-5:10 pm

1 stop10h 40m

Knoxville McGhee Tyson

Mon 8/10

12:30 pm-9:50 pm

1 stop9h 20m

$362
Quickest round-trip

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Thu 6/11

5:10 pm-10:30 pm

1 stop5h 20m

Knoxville McGhee Tyson

Wed 6/17

8:10 am-12:25 pm

1 stop4h 15m

$374

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Mon 7/27

5:10 pm-10:30 pm

1 stop5h 20m

Knoxville McGhee Tyson

Mon 8/3

7:30 am-4:25 pm

1 stop8h 55m

$382

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Mon 6/29

5:10 pm-10:30 pm

1 stop5h 20m

Knoxville McGhee Tyson

Wed 7/1

12:45 pm-10:45 pm

2 stops10h 00m

$382

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Sat 9/19

3:00 pm-7:20 pm

1 stop4h 20m

Knoxville McGhee Tyson

Fri 9/25

12:30 pm-9:50 pm

1 stop9h 20m

$389

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Thu 10/22

9:10 am-4:45 pm

2 stops7h 35m

Knoxville McGhee Tyson

Sun 10/25

7:15 am-9:45 pm

2 stops14h 30m

$394

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Thu 10/1

2:10 pm-9:55 pm

1 stop7h 45m

Knoxville McGhee Tyson

Sun 10/4

7:15 am-12:10 pm

1 stop4h 55m

$405
Cheapest one-way

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Tue 6/9

5:41 am-12:35 pm

2 stops6h 54m

$171

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/13

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

Compare providers for flights from Manchester to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Manchester to Knoxville in May.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Manchester, New Hampshire-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Manchester, New Hampshire-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Manchester, New Hampshire-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Manchester, New Hampshire-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Manchester, New Hampshire-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Manchester to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Manchester with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Knoxville

How far ahead should I book a flight from Manchester, New Hampshire to Knoxville?

The best time to book flights from Manchester, New Hampshire to Knoxville is 35 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Manchester, New Hampshire to Knoxville?

Currently, August is the cheapest month in which you can book a flight from Manchester, New Hampshire to Knoxville (average of $323). Flying from Manchester, New Hampshire to Knoxville in December is currently the most expensive (average of $497). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Manchester, New Hampshire to Knoxville?

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated May 17, 2026.
Read reviews from past customers who have flown Southwest,United Airlines, andAmerican Airlines from Manchester to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,292 reviews

Crew

8.6

Overall

8.0

Food

7.0

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Southwest
8.0
Very good
4,292 reviews
Southwest
8.0
Very good
4,292 reviews

Crew

8.6

Overall

8.0

Food

7.0

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
United Airlines
7.4
Good
9,730 reviews
Southwest
8.0
Very good
4,292 reviews

Crew

8.6

Overall

8.0

Food

7.0

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
American Airlines
7.1
Good
11,654 reviews
Southwest
8.0
Very good
4,292 reviews

Crew

8.6

Overall

8.0

Food

7.0

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Related info for your journey

Find useful and relevant information for your journey from Manchester to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Manchester, New Hampshire to Knoxville?

    Departing from Manchester, New Hampshire to Knoxville will take you 10h 05m. Airlines will cover a distance of 830 mi.

  • What are the cheapest airlines flying from Manchester, New Hampshire to Knoxville round-trip?

    Cheapflights users have booked flights from Manchester, New Hampshire to Knoxville round-trip from $248. Other airlines that can offer you cheap pricing are United Airlines, from $285, and Southwest, from $325. These flights start at 42% lower than the current average price 3 months from now.

  • Can I find deals for flights from Manchester to Knoxville that include hotel bookings?

    Yes. In addition to deals on Manchester to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Knoxville.

  • Can I find deals for business class flights from Manchester to Knoxville?

    Yes. Cheapflights offers flight deals from Manchester to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester, New Hampshire to Knoxville?

    Currently, August is the cheapest month in which you can book a flight from Manchester, New Hampshire to Knoxville (average of $323). Flying from Manchester, New Hampshire to Knoxville in December is currently the most expensive (average of $497). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa
Oak Ridge

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Top 3 airlines flying from Manchester to Knoxville

Discover the top 3 airlines that operate flights from Manchester to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 17, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$418FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$285Average$428FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$325Average$432FlexibilityNo cancel feeOn-time63%

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