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Knoxville

$152+ Cheap flights from Manchester, NH to Knoxville (MHT - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/15. Fares are subject to change and may not be available on all flights or dates of travel.
MHT — TYS
Aug 27 — Sep 31
Thu 8/27
Thu 9/3
1 adult, Economy
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Cheap flight deals from Manchester to Knoxville

Cheapest flights from Manchester to Knoxville
Explore the most affordable flight options available from Manchester to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 28, 2026.

This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/235:04 pm
MHT
-
TYS
1 stop4h 38m
American Airlines
Sat 9/266:15 am
TYS
-
MHT
1 stop4h 29m
American Airlines
Deal found 7/23$295
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/210:33 am
MHT
-
TYS
1 stop7h 31m
American Airlines
Sun 9/67:00 am
TYS
-
MHT
1 stop4h 51m
American Airlines
Deal found 7/24$300
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:30 am
MHT
-
TYS
1 stop10h 40m
Southwest
Wed 9/1612:45 pm
TYS
-
MHT
2 stops9h 10m
Southwest
Deal found 7/25$314
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/154:44 pm
MHT
-
TYS
1 stop4h 22m
American Airlines
Fri 9/186:15 am
TYS
-
MHT
1 stop4h 29m
American Airlines
Deal found 7/24$333
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/177:41 pm
MHT
-
TYS
1 stop4h 18m
United Airlines
Mon 8/247:00 am
TYS
-
MHT
2 stops12h 00m
United Airlines
Deal found 7/24$337
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/152:46 pm
MHT
-
TYS
2 stops9h 37m
United Airlines
Fri 9/187:20 pm
TYS
-
MHT
1 stop4h 39m
United Airlines
Deal found 7/24$338
This Southwest deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/153:05 pm
MHT
-
TYS
1 stop4h 50m
Southwest
Sat 9/1912:30 pm
TYS
-
MHT
1 stop7h 15m
Southwest
Deal found 7/24$345

Find flight deals from Manchester to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MHT) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$295
(American Airlines)

One-way from

$152
(Southwest)

Popular in

July

Cheapest in

August

Average price

$587
Provider with most accurate pricing for Manchester-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Manchester-Knoxville McGhee Tyson flights.
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From Manchester to Knoxville McGhee Tyson
Search Deals
One-way flight from Manchester to Knoxville McGhee Tyson
Search Deals
High demand for flights, 2% potential price rise
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Manchester to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 28, 2026.
Use the filters below to find and compare flights from Manchester to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Mon 9/14

7:41 pm-11:59 pm

1 stop4h 18m

Knoxville McGhee Tyson

Fri 9/18

7:20 pm-11:59 pm

1 stop4h 39m

$345

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Tue 9/15

3:05 pm-7:55 pm

1 stop4h 50m

Knoxville McGhee Tyson

Sat 9/19

12:30 pm-7:45 pm

1 stop7h 15m

$345

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Thu 9/3

6:30 am-5:10 pm

1 stop10h 40m

Knoxville McGhee Tyson

Tue 9/8

12:45 pm-9:55 pm

2 stops9h 10m

$376

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Wed 10/21

8:50 am-4:40 pm

2 stops7h 50m

Knoxville McGhee Tyson

Sat 10/24

6:40 am-4:00 pm

1 stop9h 20m

$376

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Tue 8/25

2:46 pm-8:24 pm

1 stop5h 38m

Knoxville McGhee Tyson

Sat 8/29

10:40 am-7:00 pm

2 stops8h 20m

$380

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Wed 9/16

9:25 am-2:37 pm

1 stop5h 12m

Knoxville McGhee Tyson

Mon 9/21

7:20 pm-11:59 pm

1 stop4h 39m

$409

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Tue 9/15

7:45 am-7:55 pm

2 stops12h 10m

Knoxville McGhee Tyson

Fri 9/18

1:00 pm-10:30 pm

2 stops9h 30m

$415
Quickest round-trip

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Thu 10/15

7:41 pm-11:59 pm

1 stop4h 18m

Knoxville McGhee Tyson

Mon 10/19

7:25 pm-11:56 pm

1 stop4h 31m

$419
Cheapest one-way

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Tue 9/15

3:05 pm-7:55 pm

1 stop4h 50m

$152

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Fri 9/11

6:00 am-10:38 am

1 stop4h 38m

$153

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/24

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

Compare providers for flights from Manchester to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Manchester to Knoxville in July.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Manchester, New Hampshire-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Manchester, New Hampshire-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Manchester, New Hampshire-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Manchester, New Hampshire-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Manchester, New Hampshire-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Manchester to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Manchester with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Knoxville

How far ahead should I book a flight from Manchester, New Hampshire to Knoxville?

The best time to book flights from Manchester, New Hampshire to Knoxville is 35 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Manchester, New Hampshire to Knoxville?

Currently, August is the cheapest month in which you can book a flight from Manchester, New Hampshire to Knoxville (average of $366). Flying from Manchester, New Hampshire to Knoxville in July is currently the most expensive (average of $587). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Manchester, New Hampshire to Knoxville?

Airfare is below average for this route at the moment.

Manchester, New Hampshire to Knoxville flights typically cost between $323 and $397 in September.
The cheapest round-trip price found within the last 5 days was $295 on American Airlines (Sep 23-Sep 26).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated July 28, 2026.
Read reviews from past customers who have flown Southwest,United Airlines, andAmerican Airlines from Manchester to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,229 reviews

Entertainment

7.5

Boarding

8.1

Crew

8.6

Food

7.0

Overall

8.0

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Libby,Jun 2026

TUS - LAS

One delay in a 2 layover flight=a good trip. The crew was great.
Southwest
8.0
Very good
4,229 reviews
Southwest
8.0
Very good
4,229 reviews

Entertainment

7.5

Boarding

8.1

Crew

8.6

Food

7.0

Overall

8.0

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Libby,Jun 2026

TUS - LAS

One delay in a 2 layover flight=a good trip. The crew was great.
United Airlines
7.4
Good
10,042 reviews
Southwest
8.0
Very good
4,229 reviews

Entertainment

7.5

Boarding

8.1

Crew

8.6

Food

7.0

Overall

8.0

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Libby,Jun 2026

TUS - LAS

One delay in a 2 layover flight=a good trip. The crew was great.
American Airlines
7.1
Good
11,837 reviews
Southwest
8.0
Very good
4,229 reviews

Entertainment

7.5

Boarding

8.1

Crew

8.6

Food

7.0

Overall

8.0

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Libby,Jun 2026

TUS - LAS

One delay in a 2 layover flight=a good trip. The crew was great.

Related info for your journey

Find useful and relevant information for your journey from Manchester to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Manchester, New Hampshire to Knoxville?

    Departing from Manchester, New Hampshire to Knoxville will take you 4h 18m. Airlines will cover a distance of 830 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Manchester, New Hampshire to Knoxville round-trip?

    Cheapflights users have booked flights from Manchester, New Hampshire to Knoxville round-trip from $279. Other airlines that can offer you cheap pricing are American Airlines, from $300, and Southwest, from $325. These flights start at 40% lower than the current average price 3 months from now.

  • Can I find deals for flights from Manchester to Knoxville that include hotel bookings?

    Yes. In addition to deals on Manchester to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Knoxville.

  • Can I find deals for business class flights from Manchester to Knoxville?

    Yes. Cheapflights offers flight deals from Manchester to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester, New Hampshire to Knoxville?

    Currently, August is the cheapest month in which you can book a flight from Manchester, New Hampshire to Knoxville (average of $366). Flying from Manchester, New Hampshire to Knoxville in July is currently the most expensive (average of $587). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa

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Top 3 airlines flying from Manchester to Knoxville

Discover the top 3 airlines that operate flights from Manchester to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$279Average$472FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$300Average$439FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$325Average$432FlexibilityNo cancel feeOn-time63%

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