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Knoxville

$51+ Cheap flights from Maine to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/24. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — TYS
Apr 19 — Apr 261
Sun 4/19
Sun 4/26
1 adult, Economy
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Cheap flight deals from Maine to Knoxville

Cheapest flights from Maine to Knoxville
Explore the most affordable flight options available from Maine to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 20, 2026.

This Cheapflightsfares deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/39:06 am
BOS
-
TYS
Nonstop2h 29m
Allegiant Air
Thu 5/76:30 am
TYS
-
BOS
Nonstop2h 16m
Allegiant Air
Deal found 3/19$129
This Cheapflightsfares deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/210:36 am
BOS
-
TYS
Nonstop2h 29m
Allegiant Air
Sun 4/57:30 am
TYS
-
BOS
Nonstop2h 16m
Allegiant Air
Deal found 3/16$135
This Booking.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/410:38 am
BOS
-
TYS
Nonstop2h 23m
Allegiant Air
Sun 6/77:30 am
TYS
-
BOS
Nonstop2h 18m
Allegiant Air
Deal found 3/19$140
This Cheapflightsfares deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1110:38 am
BOS
-
TYS
Nonstop2h 23m
Allegiant Air
Sun 6/147:30 am
TYS
-
BOS
Nonstop2h 18m
Allegiant Air
Deal found 3/16$145
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/39:06 am
BOS
-
TYS
Nonstop2h 29m
Multiple Airlines
Thu 5/711:27 am
TYS
-
BOS
1 stop11h 55m
Multiple Airlines
Deal found 3/18$146
This Cheapflightsfares deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/210:36 am
BOS
-
TYS
Nonstop2h 29m
Allegiant Air
Thu 4/96:00 am
TYS
-
BOS
Nonstop2h 16m
Allegiant Air
Deal found 3/16$150
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/39:06 am
BOS
-
TYS
Nonstop2h 29m
Allegiant Air
Sun 5/106:30 am
TYS
-
BOS
Nonstop2h 16m
Allegiant Air
Deal found 3/17$152
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/22:35 pm
BGR
-
TYS
1 stop21h 37m
Multiple Airlines
Tue 6/911:32 am
TYS
-
BGR
1 stop21h 54m
Multiple Airlines
Deal found 3/15$272
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/312:37 pm
BGR
-
TYS
1 stop9h 56m
Multiple Airlines
Thu 5/79:40 pm
TYS
-
BGR
2 stops44h 39m
Multiple Airlines
Deal found 3/16$295
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/127:53 pm
BGR
-
TYS
1 stop26h 31m
Multiple Airlines
Sun 4/191:14 pm
TYS
-
BGR
1 stop29h 00m
Multiple Airlines
Deal found 3/15$301
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:55 pm
BGR
-
TYS
1 stop22h 33m
Multiple Airlines
Tue 5/262:22 pm
TYS
-
BGR
1 stop19h 04m
Multiple Airlines
Deal found 3/17$302
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2212:05 pm
BGR
-
TYS
1 stop27h 52m
Multiple Airlines
Tue 5/262:22 pm
TYS
-
BGR
1 stop19h 04m
Multiple Airlines
Deal found 3/17$304

Find flight deals from Maine to Knoxville

Keep the following information in mind while searching for Maine to Knoxville flight deals. Data was last updated March 20, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$129
(Cheapflightsfares)

One-way from

$51
(Booking.com)

Popular in

December

Cheapest in

January

Average price

$421
Provider with most accurate pricing for Portland-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-Knoxville McGhee Tyson flights.
Search Deals
From Maine to Knoxville McGhee Tyson
Search Deals
One-way flight from Maine to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($56 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($28 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Maine to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 20, 2026.
Use the filters below to find and compare flights from Maine to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

BangorKnoxville

BGR - TYS

BGRTYS

Bangor

Tue 6/2

2:35 pm-12:12 pm

1 stop21h 37m

Knoxville McGhee Tyson

Tue 6/9

11:32 am-9:26 am

1 stop21h 54m

$272

BostonKnoxville

BOS - TYS

BOSTYS

Boston Logan Intl

Tue 4/14

10:45 am-7:40 pm

2 stops8h 55m

Knoxville McGhee Tyson

Tue 4/21

8:15 am-12:15 pm

1 stop4h 00m

$282
Quickest round-trip

BostonKnoxville

BOS - TYS

BOSTYS

Boston Logan Intl

Wed 4/8

5:45 am-10:50 am

1 stop5h 05m

Knoxville McGhee Tyson

Sat 4/11

7:20 pm-11:59 pm

1 stop4h 39m

$287

BangorKnoxville

BGR - TYS

BGRTYS

Bangor

Sun 5/3

12:37 pm-10:33 pm

1 stop9h 56m

Knoxville McGhee Tyson

Thu 5/7

9:40 pm-6:19 pm

2 stops44h 39m

$295

BostonKnoxville

BOS - TYS

BOSTYS

Boston Logan Intl

Thu 8/20

7:40 am-5:10 pm

2 stops9h 30m

Knoxville McGhee Tyson

Tue 8/25

8:00 am-4:10 pm

2 stops8h 10m

$337

PortlandKnoxville

PWM - TYS

PWMTYS

Portland

Tue 6/2

3:55 pm-8:50 pm

1 stop4h 55m

Knoxville McGhee Tyson

Tue 6/9

12:45 pm-10:55 pm

2 stops10h 10m

$344

PortlandKnoxville

PWM - TYS

PWMTYS

Portland

Tue 6/30

5:30 am-5:00 pm

2 stops11h 30m

Knoxville McGhee Tyson

Wed 7/15

12:45 pm-10:55 pm

2 stops10h 10m

$349

PortlandKnoxville

PWM - TYS

PWMTYS

Portland

Wed 5/13

6:10 am-5:10 pm

2 stops11h 00m

Knoxville McGhee Tyson

Wed 5/20

12:50 pm-10:35 pm

2 stops9h 45m

$349

BostonKnoxville

BOS - TYS

BOSTYS

Boston Logan Intl

Thu 6/4

5:45 am-1:45 pm

2 stops8h 00m

Knoxville McGhee Tyson

Sun 6/14

7:00 pm-12:55 am

1 stop5h 55m

$351

BostonKnoxville

BOS - TYS

BOSTYS

Boston Logan Intl

Wed 4/8

7:35 am-5:10 pm

2 stops9h 35m

Knoxville McGhee Tyson

Sat 4/11

6:40 am-1:10 pm

1 stop6h 30m

$366

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/19

Showing 1-10 of 48 resultsSorted by cheapest first
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Best time to book a flight from Maine to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Maine with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Maine to Knoxville

What is the cheapest month to book a flight from Maine to Knoxville?

Currently, October is the cheapest month in which you can book a flight from Maine to Knoxville (average of $161). Flying from Maine to Knoxville in February is currently the most expensive (average of $258). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Maine to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Maine?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson (TYS) is the airport most travelers will use when flying to Knoxville from Maine.

  • How long is the flight from Maine to Knoxville?

    For as low as $393, Southwest can have you in Knoxville from Maine in 4h 59m. Airlines will cover a distance of 1009 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Maine to Knoxville?

    When deciding which route to take from Maine to Knoxville consider Boston Logan Intl - Knoxville McGhee Tyson, Portland - Knoxville McGhee Tyson or Bangor - Knoxville McGhee Tyson as they are the most popular.

  • Can I find deals for flights from Maine to Knoxville that include hotel bookings?

    Yes. In addition to deals on Maine to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Maine to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Maine to Knoxville.

  • Can I find deals for business class flights from Maine to Knoxville?

    Yes. Cheapflights offers flight deals from Maine to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Maine to Knoxville?

    Currently, October is the cheapest month in which you can book a flight from Maine to Knoxville (average of $161). Flying from Maine to Knoxville in February is currently the most expensive (average of $258). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Murphy
Oak Ridge

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Maine to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Maine to Knoxville

Discover the top 4 airlines that operate flights from Maine to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 20, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$258Average$377FlexibilityNo cancel feeOn-time71%
DeltaCheapest$258Average$389FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$278Average$476FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$293Average$413FlexibilityNo cancel feeOn-time63%

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