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Knoxville

$55+ Cheap flights from Maine to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/8. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — TYS
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheap flight deals from Maine to Knoxville

Cheapest flights from Maine to Knoxville
Explore the most affordable flight options available from Maine to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/309:00 amBOS - TYS
Nonstop2h 31mMultiple Airlines
Fri 1/96:00 amTYS - BOS
1 stop17h 19mMultiple Airlines
Deal found 12/16$199
This Kiwi.com deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/309:00 amBOS - TYS
Nonstop2h 31mAllegiant Air
Sat 1/36:00 amTYS - BOS
Nonstop2h 10mAllegiant Air
Deal found 12/17$212
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/309:00 amBOS - TYS
Nonstop2h 31mMultiple Airlines
Mon 1/126:18 pmTYS - BOS
1 stop20h 20mMultiple Airlines
Deal found 12/16$215
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/309:00 amBOS - TYS
Nonstop2h 31mMultiple Airlines
Tue 1/131:00 pmTYS - BOS
1 stop25h 38mMultiple Airlines
Deal found 12/16$228
This Kiwi.com deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/309:00 amBOS - TYS
Nonstop2h 31mMultiple Airlines
Thu 1/81:39 pmTYS - BOS
2 stops33h 40mMultiple Airlines
Deal found 12/17$231
This Kiwi.com deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/309:00 amBOS - TYS
Nonstop2h 31mMultiple Airlines
Tue 1/65:37 pmTYS - BOS
1 stop17h 57mMultiple Airlines
Deal found 12/17$239
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/309:00 amBOS - TYS
Nonstop2h 31mMultiple Airlines
Sat 1/105:30 pmTYS - BOS
1 stop16h 41mMultiple Airlines
Deal found 12/16$241
This Mytrip deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/219:00 amBOS - TYS
Nonstop2h 31mAllegiant Air
Thu 12/259:45 amTYS - BOS
Nonstop2h 10mAllegiant Air
Deal found 12/17$244
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/189:00 amBOS - TYS
Nonstop2h 31mMultiple Airlines
Mon 12/225:38 pmTYS - BOS
1 stop16h 29mMultiple Airlines
Deal found 12/16$263
This Mytrip deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3111:15 amBGR - TYS
1 stop11h 36mAllegiant Air
Sun 1/48:00 amTYS - BGR
1 stop11h 02mAllegiant Air
Deal found 12/16$452
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3112:21 pmPWM - TYS
1 stop4h 17mAmerican Airlines
Sun 1/46:25 pmTYS - PWM
1 stop4h 30mAmerican Airlines
Deal found 12/16$489
This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/307:52 pmBGR - TYS
1 stop25h 15mAllegiant Air
Sat 1/37:27 pmTYS - BGR
1 stop23h 35mAllegiant Air
Deal found 12/14$508

Find flight deals from Maine to Knoxville

Keep the following information in mind while searching for Maine to Knoxville flight deals. Data was last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$80
(Cheapflightsfares)

One-way from

$55
(Booking.com)

Popular in

January

Cheapest in

February

Average price

$367
Provider with most accurate pricing for Boston Logan Intl-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Boston Logan Intl-Knoxville McGhee Tyson flights.
Search Deals
From Maine to Knoxville McGhee Tyson
Search Deals
One-way flight from Maine to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($46 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($19 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Maine to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Maine to Knoxville that are best for you.

Fly from

Maine

Fly to

Knoxville

Route

Depart

Return

Price

BostonKnoxville

BOS - TYS

BOSTYS

Boston Logan Intl

Thu 2/12

9:29 am-12:12 pm

Nonstop2h 43m

Knoxville McGhee Tyson

Sun 2/15

6:30 am-8:39 am

Nonstop2h 09m

$80

BostonKnoxville

BOS - TYS

BOSTYS

Boston Logan Intl

Sat 1/17

3:43 pm-5:53 pm

2 stops26h 10m

Knoxville McGhee Tyson

Sat 1/24

12:30 pm-11:19 pm

1 stop10h 49m

$194

BostonKnoxville

BOS - TYS

BOSTYS

Boston Logan Intl

Tue 12/30

9:00 am-11:31 am

Nonstop2h 31m

Knoxville McGhee Tyson

Sat 1/3

6:00 am-8:10 am

Nonstop2h 10m

$212

BostonKnoxville

BOS - TYS

BOSTYS

Boston Logan Intl

Wed 1/14

5:23 pm-5:53 pm

2 stops24h 30m

Knoxville McGhee Tyson

Wed 1/21

4:47 pm-11:57 pm

1 stop7h 10m

$216

PortlandKnoxville

PWM - TYS

PWMTYS

Portland

Thu 1/15

5:20 am-10:49 am

1 stop5h 29m

Knoxville McGhee Tyson

Tue 1/20

7:44 am-12:05 pm

1 stop4h 21m

$233

PortlandKnoxville

PWM - TYS

PWMTYS

Portland

Thu 1/15

6:00 am-11:12 am

1 stop5h 12m

Knoxville McGhee Tyson

Tue 1/20

6:10 am-11:20 am

1 stop5h 10m

$233

PortlandKnoxville

PWM - TYS

PWMTYS

Portland

Mon 1/12

5:07 pm-9:44 pm

1 stop4h 37m

Knoxville McGhee Tyson

Thu 1/15

6:00 am-12:06 pm

1 stop6h 06m

$256

BangorKnoxville

BGR - TYS

BGRTYS

Bangor

Thu 2/5

7:54 pm-10:28 pm

1 stop26h 34m

Knoxville McGhee Tyson

Sun 2/8

8:30 am-6:05 pm

1 stop9h 35m

$261

BostonKnoxville

BOS - TYS

BOSTYS

Boston Logan Intl

Fri 1/9

5:34 am-1:40 pm

1 stop8h 06m

Knoxville McGhee Tyson

Sun 1/11

7:26 pm-1:19 am

2 stops29h 53m

$269

BostonKnoxville

BOS - TYS

BOSTYS

Boston Logan Intl

Fri 1/30

11:21 am-4:49 pm

1 stop5h 28m

Knoxville McGhee Tyson

Tue 2/3

11:19 am-5:05 pm

1 stop5h 46m

$273

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/14

Showing 1-10 of 39 results
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Best time to book a flight from Maine to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Maine with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Maine to Knoxville

What is the cheapest month to book a flight from Maine to Knoxville?

Currently, October is the cheapest month in which you can book a flight from Maine to Knoxville (average of $161). Flying from Maine to Knoxville in February is currently the most expensive (average of $258). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ME to TYS?

Find hourly flight availability from Maine to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

A simple way to save on the total cost of your ticket is to fly from Maine to Knoxville in the evening. If you’re flexible enough to do this you can expect to save up to 17% on your trip compared to booking a flight at noon.

Related info for your journey

Find useful and relevant information for your journey from Maine to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Maine?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson (TYS) is the airport most travelers will use when flying to Knoxville from Maine.

  • How long is the flight from Maine to Knoxville?

    For as low as $80, Allegiant Air can have you in Knoxville from Maine in 2h 43m. Airlines will cover a distance of 829 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Maine to Knoxville?

    When deciding which route to take from Maine to Knoxville consider Boston Logan Intl - Knoxville McGhee Tyson, Portland - Knoxville McGhee Tyson or Bangor - Knoxville McGhee Tyson as they are the most popular.

  • Can I find deals for flights from Maine to Knoxville that include hotel bookings?

    Yes. In addition to deals on Maine to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Maine to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Maine to Knoxville.

  • Can I find deals for business class flights from Maine to Knoxville?

    Yes. Cheapflights offers flight deals from Maine to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Maine to Knoxville?

    Currently, October is the cheapest month in which you can book a flight from Maine to Knoxville (average of $161). Flying from Maine to Knoxville in February is currently the most expensive (average of $258). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Oak Ridge
Murphy

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Alternative routes for Maine to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Maine to Knoxville

Discover the top 3 airlines that operate flights from Maine to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$258Average$377FlexibilityNo cancel feeOn-time71%
DeltaCheapest$258Average$418FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$424Average$523FlexibilityNo cancel feeOn-time69%

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