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$65+ Cheap flights from Key West to Knoxville (EYW - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/6. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — TYS
Sep 11 — Sep 181
Fri 9/11
Fri 9/18
1 adult, Economy
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Cheap flight deals from Key West to Knoxville

Cheapest flights from Key West to Knoxville
Explore the most affordable flight options available from Key West to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 12, 2026.

This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1410:31 am -
Nonstop2h 15m
Mon 8/177:30 am -
Nonstop2h 11m
Deal found 8/7$104
This Booking.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/29:54 am -
Nonstop2h 13m
Fri 10/237:00 am -
Nonstop2h 04m
Deal found 8/11$123
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1010:31 am -
Nonstop2h 15m
Mon 8/177:30 am -
Nonstop2h 11m
Deal found 8/7$150
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1010:31 am -
Nonstop2h 15m
Fri 8/147:30 am -
Nonstop2h 11m
Deal found 8/7$169
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1410:31 am -
Nonstop2h 15m
Sat 8/156:00 pm -
1 stop19h 42m
Deal found 8/7$170
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1410:31 am -
Nonstop2h 15m
Sun 8/168:15 am -
1 stop7h 12m
Deal found 8/7$176
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1410:31 am -
Nonstop2h 15m
Fri 8/147:15 pm -
1 stop20h 30m
Deal found 8/7$178
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/28:34 am -
1 stop14h 24m
Fri 10/239:41 pm -
1 stop11h 43m
Deal found 8/11$189
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/134:17 pm -
1 stop6h 08m
Mon 8/177:30 am -
Nonstop2h 11m
Deal found 8/7$196
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/134:17 pm -
1 stop6h 08m
Fri 8/147:30 am -
Nonstop2h 11m
Deal found 8/7$217
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1010:31 am -
Nonstop2h 15m
Sat 8/156:00 pm -
1 stop19h 42m
Deal found 8/7$220

Find flight deals from Key West to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Key West (EYW) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 12, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$123
(Booking.com)

One-way from

$65
(FlightHub)

Popular in

September

Cheapest in

March

Average price

$498

Good round-trip deal

$131 or less

Good one-way deal

$180 or less
Provider with most accurate pricing for Key West-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Key West-Knoxville McGhee Tyson flights.
Search Deals
From Key West to Knoxville McGhee Tyson
Search Deals
One-way flight from Key West to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 33% potential increase in price ($144 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 13% potential price decrease ($35 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in August 2026
Search Deals
Price to beat on a round-trip flight from Key West to Knoxville McGhee Tyson.
Search Deals
Price to beat on a one-way flight from Key West to Knoxville McGhee Tyson.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Key West to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 12, 2026.
Use the filters below to find and compare flights from Key West to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Key WestKnoxville

EYW Key West - TYS Knoxville McGhee Tyson

EYWTYS

Key West

Fri 10/2

9:54 am-12:07 pm

Nonstop2h 13m

Knoxville McGhee Tyson

Fri 10/23

7:00 am-9:04 am

Nonstop2h 04m

$123

Key WestKnoxville

EYW Key West - TYS Knoxville McGhee Tyson

EYWTYS

Key West

Fri 10/2

8:34 am-10:58 pm

1 stop14h 24m

Knoxville McGhee Tyson

Fri 10/23

9:41 pm-9:24 am

1 stop11h 43m

$189

Key WestKnoxville

EYW Key West - TYS Knoxville McGhee Tyson

EYWTYS

Key West

Wed 9/23

12:53 pm-10:44 am

1 stop21h 51m

Knoxville McGhee Tyson

Wed 9/30

3:32 pm-7:42 am

1 stop16h 10m

$297

Key WestKnoxville

EYW Key West - TYS Knoxville McGhee Tyson

EYWTYS

Key West

Fri 9/4

12:07 pm-10:56 pm

1 stop10h 49m

Knoxville McGhee Tyson

Mon 9/7

9:00 am-9:24 am

2 stops48h 24m

$308

Key WestKnoxville

EYW Key West - TYS Knoxville McGhee Tyson

EYWTYS

Key West

Sat 9/5

1:35 pm-7:10 pm

1 stop5h 35m

Knoxville McGhee Tyson

Mon 9/7

6:06 am-1:05 pm

1 stop6h 59m

$319

Key WestKnoxville

EYW Key West - TYS Knoxville McGhee Tyson

EYWTYS

Key West

Fri 9/4

1:50 pm-8:59 pm

1 stop7h 09m

Knoxville McGhee Tyson

Mon 9/7

6:06 am-10:56 am

1 stop4h 50m

$319

Key WestKnoxville

EYW Key West - TYS Knoxville McGhee Tyson

EYWTYS

Key West

Wed 9/23

11:30 am-9:06 pm

2 stops9h 36m

Knoxville McGhee Tyson

Wed 9/30

6:15 am-1:17 pm

2 stops7h 02m

$429
Cheapest one-way
Quickest one-way

Key WestKnoxville

EYW Key West - TYS Knoxville McGhee Tyson

EYWTYS

Key West

Fri 11/6

10:14 am-12:27 pm

Nonstop2h 13m

$65

Key WestKnoxville

EYW Key West - TYS Knoxville McGhee Tyson

EYWTYS

Key West

Fri 11/6

7:18 pm-11:58 pm

1 stop4h 40m

$274

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/9

Sorted by cheapest first

Compare providers for flights from Key West to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Key West to Knoxville in August.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Key West-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Key West-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Key West-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Key West-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Key West-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Key West to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Key West with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Key West to Knoxville

What is the cheapest time of day to fly from EYW to TYS?

Find hourly flight availability from Key West to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 12, 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Key West to Knoxville as you normally would.

How much does it cost to fly round-trip from Key West to Knoxville?

Airfare is below average for this route at the moment.

Key West to Knoxville flights typically cost between $485 and $572 in October.
The cheapest round-trip price found within the last 5 days was $123 on Allegiant Air (Oct 2-Oct 23).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated August 12, 2026.
Read reviews from past customers who have flown Allegiant Air from Key West to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Allegiant Air
7.3
Good
679 reviews

Comfort

6.9

Boarding

7.7

Overall

7.3

Entertainment

5.5

Food

5.9

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Nic,Aug 2026

SRQ - ALB

Worker at gate refused to let me measure my personal item and insisted it needed to be a carryon and to pay 75$. I understand if it’s too big but she wouldn’t even let me go measure it. She eventually let me measure my own luggage after back n forth. It is a few inches too big and she comes over and attempts to grab my suitcase out my hands and I pull it away from her. She then shuts the door of the gate and says to call the police. I then just offer to pay for the carryon and she says ok. Then refuses to use let me use my tap to pay, luckily I had my physical card on me. As soon as I walked out the door I respectfully asked for her name. She began screaming at me and threatening me. This worker was just so hostile I understand if my stuffs too big I will pay the difference I’m not trying to get over on the rules. I was confused because I was allowed to board my destination flight with this item as a personal item. So I was confused by this whole situation from the go. It also caused a massive scene at the airport and I was extremely embarrassed. It genuinely seemed like this worker was out to get me for some reason. I had literally just arrived to the gate as it was already boarding so I hadn’t done anything prior. Super weird situation and it really spooked me.
Allegiant Air
7.3
Good
679 reviews
Allegiant Air
7.3
Good
679 reviews

Comfort

6.9

Boarding

7.7

Overall

7.3

Entertainment

5.5

Food

5.9

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Nic,Aug 2026

SRQ - ALB

Worker at gate refused to let me measure my personal item and insisted it needed to be a carryon and to pay 75$. I understand if it’s too big but she wouldn’t even let me go measure it. She eventually let me measure my own luggage after back n forth. It is a few inches too big and she comes over and attempts to grab my suitcase out my hands and I pull it away from her. She then shuts the door of the gate and says to call the police. I then just offer to pay for the carryon and she says ok. Then refuses to use let me use my tap to pay, luckily I had my physical card on me. As soon as I walked out the door I respectfully asked for her name. She began screaming at me and threatening me. This worker was just so hostile I understand if my stuffs too big I will pay the difference I’m not trying to get over on the rules. I was confused because I was allowed to board my destination flight with this item as a personal item. So I was confused by this whole situation from the go. It also caused a massive scene at the airport and I was extremely embarrassed. It genuinely seemed like this worker was out to get me for some reason. I had literally just arrived to the gate as it was already boarding so I hadn’t done anything prior. Super weird situation and it really spooked me.

Related info for your journey

Find useful and relevant information for your journey from Key West to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Key West to Knoxville?

    Departing from Key West to Knoxville will take you 2h 13m. Key West and Knoxville are separated by a distance of 788 mi. Most flights are nonstop.

  • What is the cheapest airline to fly from Key West to Knoxville round-trip?

    Allegiant Air, at $91, was found to be the cheapest airline from Key West to Knoxville.. You may be able to fly from Key West to Knoxville for 68% less than the average price by searching for this airline.

  • What are the cheapest flights from Key West to Knoxville?

    While on average a flight from Key West to Knoxville is generally $178, our data shows the cheapest flight currently is $91. When looking at the most popular route, (Key West - Knoxville McGhee Tyson), you can expect to pay $123 for that flight.

  • Can I find deals for flights from Key West to Knoxville that include hotel bookings?

    Yes. In addition to deals on Key West to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key West to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key West to Knoxville.

  • Can I find deals for business class flights from Key West to Knoxville?

    Yes. Cheapflights offers flight deals from Key West to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa

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Top airline flying from Key West to Knoxville

Discover the top airline that operate flights from Key West to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 12, 2026.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$91Average$148FlexibilityNo cancel feeOn-time88%

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