How long is the flight from Key West to Knoxville?

Departing from Key West to Knoxville will take you 4h 02m. Key West and Knoxville are separated by a distance of 788 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

What is the cheapest airline to fly from Key West to Knoxville round-trip?

Allegiant Air, at $91, was found to be the cheapest airline from Key West to Knoxville.. You may be able to fly from Key West to Knoxville for 64% less than the average price by searching for this airline.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

What are the cheapest flights from Key West to Knoxville?

While on average a flight from Key West to Knoxville is generally $178, our data shows the cheapest flight currently is $91. When looking at the most popular route, (Key West - Knoxville McGhee Tyson), you can expect to pay $127 for that flight.

What is the cheapest time of day to fly from EYW to TYS?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Key West to Knoxville as you normally would.

Most accurate provider : When it comes to deals on Key West-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Key West-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Key West-Knoxville flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Key West-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Key West-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Key West to Knoxville that include hotel bookings?

Yes. In addition to deals on Key West to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Key West to Knoxville?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key West to Knoxville.

Can I find deals for business class flights from Key West to Knoxville?

Yes. Cheapflights offers flight deals from Key West to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$37+ Cheap Flights from Key West to Knoxville

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Cheap flight deals from Key West to Knoxville

Cheapest

Best

Last-minute

One-way

Cheapest flights from Key West to Knoxville
Explore the most affordable flight options available from Key West to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 28, 2026.

Fri 10/29:54 am -

Nonstop2h 13m

Mon 10/199:00 am -

Nonstop2h 04m

Deal found 8/24

$90

Fri 10/29:54 am -

Nonstop2h 13m

Mon 10/58:00 am -

Nonstop2h 04m

Deal found 8/27

$127

Fri 10/212:59 pm -

2 stops9h 35m

Mon 10/199:00 am -

Nonstop2h 04m

Deal found 8/24

$207

Thu 9/105:09 pm -

1 stop15h 05m

Mon 9/145:40 pm -

2 stops39h 44m

Deal found 8/25

$276

Fri 9/118:58 am -

1 stop8h 44m

Tue 9/153:21 pm -

1 stop20h 42m

Deal found 8/27

$280

Fri 10/99:14 am -

Nonstop2h 13m

Mon 10/129:00 am -

Nonstop2h 04m

Deal found 8/25

$288

Fri 9/1112:59 pm -

2 stops21h 15m

Tue 9/153:21 pm -

1 stop20h 42m

Deal found 8/27

$300

Fri 9/118:58 am -

1 stop8h 44m

Mon 9/145:40 pm -

2 stops39h 44m

Deal found 8/25

$308

Thu 12/107:57 pm -

1 stop4h 02m

Mon 12/146:00 am -

1 stop4h 44m

Deal found 8/28

$319

Best flights from Key West to Knoxville
Discover carefully curated flight deals from Key West to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 28, 2026.

Thu 12/107:57 pm -

1 stop4h 02m

Mon 12/146:00 am -

1 stop4h 44m

Deal found 8/28

$319

Wed 9/912:53 pm -

1 stop21h 51m

Mon 9/145:40 pm -

2 stops39h 44m

Deal found 8/25

$321

Fri 9/116:19 pm -

1 stop4h 08m

Mon 9/148:55 am -

1 stop3h 58m

Deal found 8/25

$341

Wed 9/96:19 pm -

1 stop4h 08m

Mon 9/145:40 am -

1 stop5h 06m

Deal found 8/25

$341

Fri 10/22:15 pm -

1 stop6h 51m

Mon 10/56:00 am -

1 stop3h 54m

Deal found 8/27

$391

Thu 9/105:09 pm -

1 stop15h 05m

Mon 9/144:18 pm -

3 stops41h 06m

Deal found 8/25

$452

Fri 10/22:00 pm -

1 stop4h 40m

Mon 10/512:23 pm -

1 stop5h 00m

Deal found 8/24

$459

Fri 10/21:47 pm -

2 stops9h 03m

Mon 10/196:56 am -

2 stops6h 07m

Deal found 8/24

$757

Last-minute flights from Key West to Knoxville
Discover last-minute flight deals from Key West to Knoxville. Data last updated August 28, 2026 and is based on user searches.

Sun 9/66:11 pm -

1 stop25h 59m

Sun 9/135:44 pm -

2 stops18h 35m

Deal found 8/23

$471

Sun 9/61:35 pm -

1 stop5h 35m

Sun 9/136:05 am -

1 stop7h 12m

Deal found 8/23

$496

Wed 9/912:53 pm -

1 stop21h 51m

Mon 9/145:40 pm -

2 stops39h 44m

Deal found 8/25

$321

Wed 9/96:19 pm -

1 stop4h 08m

Mon 9/145:40 am -

1 stop5h 06m

Deal found 8/25

$341

Thu 9/105:09 pm -

1 stop15h 05m

Mon 9/145:40 pm -

2 stops39h 44m

Deal found 8/25

$276

Fri 9/118:58 am -

1 stop8h 44m

Tue 9/153:21 pm -

1 stop20h 42m

Deal found 8/27

$280

Fri 9/1112:59 pm -

2 stops21h 15m

Tue 9/153:21 pm -

1 stop20h 42m

Deal found 8/27

$300

Fri 9/118:58 am -

1 stop8h 44m

Mon 9/145:40 pm -

2 stops39h 44m

Deal found 8/25

$308

Fri 9/111:47 pm -

2 stops7h 19m

Tue 9/156:15 am -

2 stops7h 02m

Deal found 8/27

$667

One-way flights from Key West to Knoxville
Search for one-way flight options from Key West to Knoxville. Find affordable one-way fares based on user searches. Data last updated August 28, 2026.

Fri 11/1310:14 am -

Nonstop2h 13m

Deal found 8/24

$37

Fri 11/610:14 am -

Nonstop2h 13m

Deal found 8/28

$48

Fri 10/1610:14 am -

Nonstop2h 13m

Deal found 8/24

$83

Tue 10/131:16 pm -

3 stops53h 24m

Deal found 8/24

$176

Fri 11/1312:59 pm -

2 stops21h 06m

Deal found 8/24

$185

Find flight deals from Key West to Knoxville

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Round-trip from	$90 (CheapOair)
One-way from	$37 (CheapOair)
Popular in	September
Cheapest in	March
Average price	$162
Good round-trip deal	$131 or less
Good one-way deal	$193 or less

Provider with most accurate pricing for Key West-Knoxville McGhee Tyson flight deals.

Search Deals

Provider most trusted by Cheapflights users for Key West-Knoxville McGhee Tyson flights.

Search Deals

From Key West to Knoxville McGhee Tyson

Search Deals

One-way flight from Key West to Knoxville McGhee Tyson

Search Deals

Highest demand for flights based on searches. 19% potential increase in price ($60 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 16% potential price decrease ($37 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in August 2026

Search Deals

Price to beat on a round-trip flight from Key West to Knoxville McGhee Tyson.

Search Deals

Price to beat on a one-way flight from Key West to Knoxville McGhee Tyson.

Search Deals

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Key WestKnoxville

EYW Key West - TYS Knoxville McGhee Tyson

EYWTYS

Key West

Thu 12/10

7:57 pm-11:59 pm

1 stop4h 02m

Knoxville McGhee Tyson

Mon 12/14

6:00 am-10:44 am

1 stop4h 44m

$319

Key WestKnoxville

EYW Key West - TYS Knoxville McGhee Tyson

EYWTYS

Key West

Wed 9/9

12:53 pm-10:44 am

1 stop21h 51m

Knoxville McGhee Tyson

Mon 9/14

5:40 pm-9:24 am

2 stops39h 44m

$321

Quickest round-trip

Key WestKnoxville

EYW Key West - TYS Knoxville McGhee Tyson

EYWTYS

Key West

Fri 9/11

6:19 pm-10:27 pm

1 stop4h 08m

Knoxville McGhee Tyson

Mon 9/14

8:55 am-12:53 pm

1 stop3h 58m

$341

Key WestKnoxville

EYW Key West - TYS Knoxville McGhee Tyson

EYWTYS

Key West

Wed 9/9

6:19 pm-10:27 pm

1 stop4h 08m

Knoxville McGhee Tyson

Mon 9/14

5:40 am-10:46 am

1 stop5h 06m

$341

Key WestKnoxville

EYW Key West - TYS Knoxville McGhee Tyson

EYWTYS

Key West

Fri 10/2

2:15 pm-9:06 pm

1 stop6h 51m

Knoxville McGhee Tyson

Mon 10/5

6:00 am-9:54 am

1 stop3h 54m

$391

Key WestKnoxville

EYW Key West - TYS Knoxville McGhee Tyson

EYWTYS

Key West

Thu 9/10

5:09 pm-8:14 am

1 stop15h 05m

Knoxville McGhee Tyson

Mon 9/14

4:18 pm-9:24 am

3 stops41h 06m

$452

Key WestKnoxville

EYW Key West - TYS Knoxville McGhee Tyson

EYWTYS

Key West

Fri 10/2

2:00 pm-6:40 pm

1 stop4h 40m

Knoxville McGhee Tyson

Mon 10/5

12:23 pm-5:23 pm

1 stop5h 00m

$459

Key WestKnoxville

EYW Key West - TYS Knoxville McGhee Tyson

EYWTYS

Key West

Fri 10/2

1:47 pm-10:50 pm

2 stops9h 03m

Knoxville McGhee Tyson

Mon 10/19

6:56 am-1:03 pm

2 stops6h 07m

$757

Cheapest one-way

Quickest one-way

Key WestKnoxville

EYW Key West - TYS Knoxville McGhee Tyson

EYWTYS

Key West

Fri 11/6

10:14 am-12:27 pm

Nonstop2h 13m

$48

Key WestKnoxville

EYW Key West - TYS Knoxville McGhee Tyson

EYWTYS

Key West

Fri 10/16

2:03 pm-9:43 am

1 stop19h 40m

$150

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/28

Showing 1-10 of 14 resultsSorted by cheapest first

Compare providers for flights from Key West to Knoxville

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Key West to Knoxville in August.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy1 star	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Key West-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Key West-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Key West-Knoxville flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Key West-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Key West-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Key West to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Key West with our price prediction graph.

EYW-TYS

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Knoxville

Read reviews from past customers who have flown Allegiant Air from Key West to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Allegiant Air

7.3

Good

676 reviews

Reviews

1 / 20

2.0

Mediocre

Nic,Aug 2026

SRQ - ALB

Worker at gate refused to let me measure my personal item and insisted it needed to be a carryon and to pay 75$. I understand if it’s too big but she wouldn’t even let me go measure it. She eventually let me measure my own luggage after back n forth. It is a few inches too big and she comes over and attempts to grab my suitcase out my hands and I pull it away from her. She then shuts the door of the gate and says to call the police. I then just offer to pay for the carryon and she says ok. Then refuses to use let me use my tap to pay, luckily I had my physical card on me. As soon as I walked out the door I respectfully asked for her name. She began screaming at me and threatening me. This worker was just so hostile I understand if my stuffs too big I will pay the difference I’m not trying to get over on the rules. I was confused because I was allowed to board my destination flight with this item as a personal item. So I was confused by this whole situation from the go. It also caused a massive scene at the airport and I was extremely embarrassed. It genuinely seemed like this worker was out to get me for some reason. I had literally just arrived to the gate as it was already boarding so I hadn’t done anything prior. Super weird situation and it really spooked me.

Allegiant Air

7.3

Good

676 reviews

Allegiant Air

7.3

Good

676 reviews

Reviews

1 / 20

2.0

Mediocre

Nic,Aug 2026

SRQ - ALB

Related info for your journey

How long is the flight from Key West to Knoxville?
Departing from Key West to Knoxville will take you 4h 02m. Key West and Knoxville are separated by a distance of 788 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.
What is the cheapest airline to fly from Key West to Knoxville round-trip?
Allegiant Air, at $91, was found to be the cheapest airline from Key West to Knoxville.. You may be able to fly from Key West to Knoxville for 64% less than the average price by searching for this airline.
What are the cheapest flights from Key West to Knoxville?
While on average a flight from Key West to Knoxville is generally $178, our data shows the cheapest flight currently is $91. When looking at the most popular route, (Key West - Knoxville McGhee Tyson), you can expect to pay $127 for that flight.
Can I find deals for flights from Key West to Knoxville that include hotel bookings?
Yes. In addition to deals on Key West to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Key West to Knoxville?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key West to Knoxville.
Can I find deals for business class flights from Key West to Knoxville?
Yes. Cheapflights offers flight deals from Key West to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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Top airline flying from Key West to Knoxville

Airline	Cheapest	Average	Flexibility	On-time
Allegiant Air	Cheapest$91	Average$148	FlexibilityNo cancel fee	On-time88%

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$37+ Cheap flights from Key West to Knoxville (EYW - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/13. Fares are subject to change and may not be available on all flights or dates of travel.

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Cheap flight deals from Key West to Knoxville

Cheapest flights from Key West to KnoxvilleExplore the most affordable flight options available from Key West to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 28, 2026.

Explore the most affordable flight options available from Key West to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 28, 2026.

Best flights from Key West to KnoxvilleDiscover carefully curated flight deals from Key West to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 28, 2026.

Discover carefully curated flight deals from Key West to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 28, 2026.

Last-minute flights from Key West to KnoxvilleDiscover last-minute flight deals from Key West to Knoxville. Data last updated August 28, 2026 and is based on user searches.

Discover last-minute flight deals from Key West to Knoxville. Data last updated August 28, 2026 and is based on user searches.

One-way flights from Key West to KnoxvilleSearch for one-way flight options from Key West to Knoxville. Find affordable one-way fares based on user searches. Data last updated August 28, 2026.

Search for one-way flight options from Key West to Knoxville. Find affordable one-way fares based on user searches. Data last updated August 28, 2026.

Find flight deals from Key West to Knoxville

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Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Cheapflights Fare Finder

Use the filters below to find and compare flights from Key West to Knoxville that are best for you.

Compare providers for flights from Key West to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Key West to Knoxville in August.

Best time to book a flight from Key West to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Key West with our price prediction graph.

Reviews of airlines servicing Knoxville

Read reviews from past customers who have flown Allegiant Air from Key West to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

How long is the flight from Key West to Knoxville?

What is the cheapest airline to fly from Key West to Knoxville round-trip?

What are the cheapest flights from Key West to Knoxville?

Can I find deals for flights from Key West to Knoxville that include hotel bookings?

How can I find direct flights from Key West to Knoxville?

Can I find deals for business class flights from Key West to Knoxville?

Traveling to a place near Knoxville?

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Alternative routes for Key West to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.

Complete your trip

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Search flights from Key West to Knoxville by cabin class

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Other flights to Knoxville

Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 28, 2026.

Key West and Knoxville flights

Browse other Key West and Knoxville flight options. Last updated on August 28, 2026.

Other flights from Key West

Browse through other flights departing from Key West. Flights are based on user searches made on Cheapflights and were last updated on August 28, 2026.

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Top airline flying from Key West to Knoxville

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Cheapest flights from Key West to Knoxville
Explore the most affordable flight options available from Key West to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 28, 2026.

Best flights from Key West to Knoxville
Discover carefully curated flight deals from Key West to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 28, 2026.

Last-minute flights from Key West to Knoxville
Discover last-minute flight deals from Key West to Knoxville. Data last updated August 28, 2026 and is based on user searches.

One-way flights from Key West to Knoxville
Search for one-way flight options from Key West to Knoxville. Find affordable one-way fares based on user searches. Data last updated August 28, 2026.