$45+ Cheap flights from Key West to Knoxville (EYW - TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/10. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — TYS
Jul 12 — Jul 191
Round-trip
1 adult, Economy
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Find cheap flights from Key West to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Key West to Knoxville
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Best
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One-way
Cheapest flights from Key West to KnoxvilleExplore the most affordable flight options available from Key West to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2026.
Explore the most affordable flight options available from Key West to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/3110:31 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Fri 8/77:30 am
TYS
- EYW
Nonstop2h 11m
Allegiant Air
Deal found 6/10![Allegiant Air logo]()
$75
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/3110:31 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Mon 8/37:30 am
TYS
- EYW
Nonstop2h 11m
Allegiant Air
Deal found 6/9![Allegiant Air logo]()
$78
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1010:31 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Fri 7/177:30 am
TYS
- EYW
Nonstop2h 11m
Allegiant Air
Deal found 6/10![Allegiant Air logo]()
$101
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/3110:31 am
EYW
- TYS
Nonstop2h 15m
Multiple Airlines
Mon 8/312:40 pm
TYS
- EYW
3 stops23h 54m
Multiple Airlines
Deal found 6/9![Multiple Airlines logo]()
$215
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/97:53 pm
EYW
- TYS
1 stop27h 26m
Multiple Airlines
Thu 7/163:53 pm
TYS
- EYW
1 stop22h 44m
Multiple Airlines
Deal found 6/11![Multiple Airlines logo]()
$220
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/155:00 pm
EYW
- TYS
1 stop19h 30m
Allegiant Air
Sat 7/186:42 pm
TYS
- EYW
1 stop20h 45m
Allegiant Air
Deal found 6/12![Allegiant Air logo]()
$239
Best flights from Key West to KnoxvilleDiscover carefully curated flight deals from Key West to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 12, 2026.
Discover carefully curated flight deals from Key West to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 12, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/3110:31 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Fri 8/77:15 pm
TYS
- EYW
2 stops38h 51m
Allegiant Air
Deal found 6/10![Allegiant Air logo]()
$207
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/97:53 pm
EYW
- TYS
1 stop27h 26m
Multiple Airlines
Thu 7/163:53 pm
TYS
- EYW
1 stop22h 44m
Multiple Airlines
Deal found 6/11![Multiple Airlines logo]()
$220
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/77:00 am
EYW
- TYS
1 stop6h 23m
Delta
Mon 12/142:30 pm
TYS
- EYW
1 stop5h 13m
Delta
Deal found 6/12![Delta logo]()
$354
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/1511:46 am
EYW
- TYS
2 stops32h 35m
Multiple Airlines
Sun 7/198:15 am
TYS
- EYW
1 stop7h 12m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$289
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/74:05 pm
EYW
- TYS
2 stops22h 37m
United Airlines
Mon 12/147:35 pm
TYS
- EYW
2 stops17h 27m
United Airlines
Deal found 6/11![United Airlines logo]()
$724
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/91:47 pm
EYW
- TYS
2 stops10h 04m
American Airlines
Thu 7/1611:03 am
TYS
- EYW
2 stops8h 03m
American Airlines
Deal found 6/11![American Airlines logo]()
$747
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/72:26 pm
EYW
- TYS
2 stops33h 28m
United Airlines
Mon 8/105:45 am
TYS
- EYW
2 stops31h 44m
United Airlines
Deal found 6/11![United Airlines logo]()
$754
Last-minute flights from Key West to KnoxvilleDiscover last-minute flight deals from Key West to Knoxville. Data last updated June 12, 2026 and is based on user searches.
Discover last-minute flight deals from Key West to Knoxville. Data last updated June 12, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/97:53 pm
EYW
- TYS
1 stop27h 26m
Multiple Airlines
Thu 7/163:53 pm
TYS
- EYW
1 stop22h 44m
Multiple Airlines
Deal found 6/11![Multiple Airlines logo]()
$220
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1010:31 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Fri 7/177:30 am
TYS
- EYW
Nonstop2h 11m
Allegiant Air
Deal found 6/10![Allegiant Air logo]()
$101
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/155:00 pm
EYW
- TYS
1 stop19h 30m
Allegiant Air
Sat 7/186:42 pm
TYS
- EYW
1 stop20h 45m
Allegiant Air
Deal found 6/12![Allegiant Air logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/3110:31 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Fri 8/77:30 am
TYS
- EYW
Nonstop2h 11m
Allegiant Air
Deal found 6/10![Allegiant Air logo]()
$75
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/3110:31 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Mon 8/37:30 am
TYS
- EYW
Nonstop2h 11m
Allegiant Air
Deal found 6/9![Allegiant Air logo]()
$78
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/3110:31 am
EYW
- TYS
Nonstop2h 15m
Multiple Airlines
Mon 8/312:40 pm
TYS
- EYW
3 stops23h 54m
Multiple Airlines
Deal found 6/9![Multiple Airlines logo]()
$215
One-way flights from Key West to KnoxvilleSearch for one-way flight options from Key West to Knoxville. Find affordable one-way fares based on user searches. Data last updated June 12, 2026.
Search for one-way flight options from Key West to Knoxville. Find affordable one-way fares based on user searches. Data last updated June 12, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1010:31 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Deal found 6/12![Allegiant Air logo]()
$45
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/235:09 pm
EYW
- TYS
1 stop22h 34m
Allegiant Air
Deal found 6/11![Allegiant Air logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/101:11 pm
EYW
- TYS
2 stops19h 21m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$179
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/2312:05 pm
EYW
- TYS
2 stops30h 30m
Multiple Airlines
Deal found 6/11![Multiple Airlines logo]()
$203
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:00 pm
EYW
- TYS
1 stop5h 46m
Delta
Deal found 6/11![Delta logo]()
$269
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:26 pm
EYW
- TYS
2 stops7h 25m
American Airlines
Deal found 6/10![American Airlines logo]()
$374
Find flight deals from Key West to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Key West (EYW) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $75 (Kiwi.com) |
One-way from | $45 (Kiwi.com) |
Popular in | September |
Cheapest in | March |
Average price | $229 |
Cheapflights Fare Finder
Customize your flight search to find flights from Key West to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2026.
Use the filters below to find and compare flights from Key West to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Key WestKnoxville
EYW - TYS
EYWTYS
Key West
Fri 7/31
10:31 am-12:46 pm
Nonstop2h 15m
Knoxville McGhee Tyson
Fri 8/7
7:15 pm-10:06 am
2 stops38h 51m
$207
Key WestKnoxville
EYW - TYS
EYWTYS
Key West
Thu 7/9
7:53 pm-11:19 pm
1 stop27h 26m
Knoxville McGhee Tyson
Thu 7/16
3:53 pm-2:37 pm
1 stop22h 44m
$220
Key WestKnoxville
EYW - TYS
EYWTYS
Key West
Wed 7/15
11:46 am-8:21 pm
2 stops32h 35m
Knoxville McGhee Tyson
Sun 7/19
8:15 am-3:27 pm
1 stop7h 12m
$289
Quickest round-trip
Key WestKnoxville
EYW - TYS
EYWTYS
Key West
Mon 12/7
7:00 am-1:23 pm
1 stop6h 23m
Knoxville McGhee Tyson
Mon 12/14
2:30 pm-7:43 pm
1 stop5h 13m
$354
Key WestKnoxville
EYW - TYS
EYWTYS
Key West
Mon 12/7
4:05 pm-2:42 pm
2 stops22h 37m
Knoxville McGhee Tyson
Mon 12/14
7:35 pm-1:02 pm
2 stops17h 27m
$724
Key WestKnoxville
EYW - TYS
EYWTYS
Key West
Thu 7/9
1:47 pm-11:51 pm
2 stops10h 04m
Knoxville McGhee Tyson
Thu 7/16
11:03 am-7:06 pm
2 stops8h 03m
$747
Key WestKnoxville
EYW - TYS
EYWTYS
Key West
Fri 8/7
2:26 pm-11:54 pm
2 stops33h 28m
Knoxville McGhee Tyson
Mon 8/10
5:45 am-1:29 pm
2 stops31h 44m
$754
Cheapest one-way
Quickest one-way
Key WestKnoxville
EYW - TYS
EYWTYS
Key West
Fri 7/10
10:31 am-12:46 pm
Nonstop2h 15m
$45
Key WestKnoxville
EYW - TYS
EYWTYS
Key West
Fri 7/10
1:11 pm-8:32 am
2 stops19h 21m
$179
Key WestKnoxville
EYW - TYS
EYWTYS
Key West
Sun 8/23
12:05 pm-6:35 pm
2 stops30h 30m
$203
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from Key West to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Key West to Knoxville in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Key West-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Key West-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Key West-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Key West-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Key West-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Key West to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Key West with our price prediction graph.
EYW-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Key West to Knoxville
What is the cheapest time of day to fly from EYW to TYS?
Find hourly flight availability from Key West to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Key West to Knoxville as you normally would.
How much does it cost to fly round-trip from Key West to Knoxville?
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated June 12, 2026.
Read reviews from past customers who have flown Allegiant Air from Key West to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.3
Crew
8.1
Comfort
6.9
Food
5.8
Entertainment
5.5
Boarding
7.6
Reviews
1 / 20
10.0
ExcellentElizabeth,Jun 2026
LAS - RAP
Overall
7.3
Crew
8.1
Comfort
6.9
Food
5.8
Entertainment
5.5
Boarding
7.6
Reviews
1 / 20
10.0
ExcellentElizabeth,Jun 2026
LAS - RAP
Related info for your journey
Find useful and relevant information for your journey from Key West to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa
Oak Ridge
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Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 12, 2026.
Key West and Knoxville flights
Browse other Key West and Knoxville flight options. Last updated on June 12, 2026.
Other flights from Key West
Browse through other flights departing from Key West. Flights are based on user searches made on Cheapflights and were last updated on June 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Key West to Knoxville
Discover the top airline that operate flights from Key West to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$92 | Average$169 | FlexibilityNo cancel fee | On-time88% |