$158+ Cheap flights from Key West to Knoxville (EYW - TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/6. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — TYS
Jul 19 — Jul 261
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Key West to KnoxvilleExplore the most affordable flight options available from Key West to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 19, 2026.
Explore the most affordable flight options available from Key West to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 19, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/107:22 pm
EYW
- TYS
1 stop25h 37m
Allegiant Air
Mon 12/1411:00 am
TYS
- EYW
Nonstop2h 12m
Allegiant Air
Deal found 6/19![Allegiant Air logo]()
$290
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:00 pm
EYW
- TYS
1 stop5h 46m
Delta
Mon 12/143:55 pm
TYS
- EYW
1 stop3h 48m
Delta
Deal found 6/16![Delta logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1012:01 pm
EYW
- TYS
2 stops20h 26m
Multiple Airlines
Mon 12/149:00 am
TYS
- EYW
1 stop25h 19m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$357
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/184:02 pm
EYW
- TYS
1 stop6h 14m
Allegiant Air
Sat 6/206:43 pm
TYS
- EYW
1 stop20h 29m
Allegiant Air
Deal found 6/15![Allegiant Air logo]()
$416
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/182:28 pm
EYW
- TYS
1 stop5h 46m
Delta
Sun 6/2110:23 am
TYS
- EYW
1 stop7h 04m
Delta
Deal found 6/15![Delta logo]()
$429
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/175:07 pm
EYW
- TYS
1 stop19h 20m
Allegiant Air
Sat 6/206:43 pm
TYS
- EYW
1 stop20h 29m
Allegiant Air
Deal found 6/15![Allegiant Air logo]()
$474
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1711:28 am
EYW
- TYS
2 stops6h 09m
American Airlines
Sun 6/216:55 am
TYS
- EYW
1 stop5h 21m
American Airlines
Deal found 6/15![American Airlines logo]()
$538
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1810:56 am
EYW
- TYS
2 stops12h 28m
Allegiant Air
Sun 6/218:15 am
TYS
- EYW
1 stop6h 57m
Allegiant Air
Deal found 6/15![Allegiant Air logo]()
$558
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1711:28 am
EYW
- TYS
2 stops6h 09m
American Airlines
Sat 6/206:55 am
TYS
- EYW
1 stop5h 21m
American Airlines
Deal found 6/15![American Airlines logo]()
$562
Best flights from Key West to KnoxvilleDiscover carefully curated flight deals from Key West to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 19, 2026.
Discover carefully curated flight deals from Key West to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 19, 2026.
This Delta deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:00 pm
EYW
- TYS
1 stop5h 46m
Delta
Mon 12/143:55 pm
TYS
- EYW
1 stop3h 48m
Delta
Deal found 6/19![Delta logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1012:01 pm
EYW
- TYS
2 stops20h 26m
Multiple Airlines
Mon 12/1411:00 am
TYS
- EYW
Nonstop2h 12m
Multiple Airlines
Deal found 6/18![Multiple Airlines logo]()
$358
This Delta deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/77:00 am
EYW
- TYS
1 stop6h 23m
Delta
Mon 12/142:30 pm
TYS
- EYW
1 stop5h 13m
Delta
Deal found 6/19![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/77:00 am
EYW
- TYS
2 stops7h 29m
American Airlines
Mon 12/142:55 pm
TYS
- EYW
2 stops8h 12m
American Airlines
Deal found 6/19![American Airlines logo]()
$747
This United Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/32:26 pm
EYW
- TYS
2 stops20h 16m
United Airlines
Fri 8/77:19 pm
TYS
- EYW
2 stops18h 11m
United Airlines
Deal found 6/18![United Airlines logo]()
$758
Last-minute flights from Key West to KnoxvilleDiscover last-minute flight deals from Key West to Knoxville. Data last updated June 19, 2026 and is based on user searches.
Discover last-minute flight deals from Key West to Knoxville. Data last updated June 19, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/184:02 pm
EYW
- TYS
1 stop6h 14m
Allegiant Air
Sat 6/206:43 pm
TYS
- EYW
1 stop20h 29m
Allegiant Air
Deal found 6/15![Allegiant Air logo]()
$416
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/182:28 pm
EYW
- TYS
1 stop5h 46m
Delta
Sun 6/2110:23 am
TYS
- EYW
1 stop7h 04m
Delta
Deal found 6/15![Delta logo]()
$429
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1810:56 am
EYW
- TYS
2 stops12h 28m
Allegiant Air
Sun 6/218:15 am
TYS
- EYW
1 stop6h 57m
Allegiant Air
Deal found 6/15![Allegiant Air logo]()
$558
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1811:28 am
EYW
- TYS
2 stops10h 30m
American Airlines
Sun 6/218:59 am
TYS
- EYW
2 stops10h 11m
American Airlines
Deal found 6/15![American Airlines logo]()
$747
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1811:28 am
EYW
- TYS
2 stops10h 30m
American Airlines
Sat 6/208:59 am
TYS
- EYW
2 stops10h 20m
American Airlines
Deal found 6/15![American Airlines logo]()
$754
This United Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/182:26 pm
EYW
- TYS
2 stops20h 16m
United Airlines
Sat 6/207:19 pm
TYS
- EYW
2 stops19h 50m
United Airlines
Deal found 6/15![United Airlines logo]()
$1,116
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/193:25 pm
EYW
- TYS
1 stop5h 48m
Allegiant Air
Sat 6/206:43 pm
TYS
- EYW
1 stop20h 29m
Allegiant Air
Deal found 6/19![Allegiant Air logo]()
$657
One-way flights from Key West to KnoxvilleSearch for one-way flight options from Key West to Knoxville. Find affordable one-way fares based on user searches. Data last updated June 19, 2026.
Search for one-way flight options from Key West to Knoxville. Find affordable one-way fares based on user searches. Data last updated June 19, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/610:31 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Deal found 6/15![Allegiant Air logo]()
$158
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/612:07 pm
EYW
- TYS
1 stop11h 26m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$187
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:00 pm
EYW
- TYS
1 stop5h 46m
Delta
Deal found 6/16![Delta logo]()
$269
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2011:45 am
EYW
- TYS
1 stop5h 33m
Delta
Deal found 6/17![Delta logo]()
$328
This American Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/202:01 pm
EYW
- TYS
2 stops9h 29m
American Airlines
Deal found 6/17![American Airlines logo]()
$392
This American Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:26 pm
EYW
- TYS
2 stops7h 25m
American Airlines
Deal found 6/19![American Airlines logo]()
$393
This United Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:05 pm
EYW
- TYS
2 stops30h 15m
United Airlines
Deal found 6/17![United Airlines logo]()
$420
This American Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/144:10 pm
EYW
- TYS
2 stops7h 47m
American Airlines
Deal found 6/17![American Airlines logo]()
$457
Find flight deals from Key West to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Key West (EYW) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 19, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $290 (Kiwi.com) |
One-way from | $158 (Kiwi.com) |
Popular in | September |
Cheapest in | March |
Average price | $288 |
Cheapflights Fare Finder
Customize your flight search to find flights from Key West to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 19, 2026.
Use the filters below to find and compare flights from Key West to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Key WestKnoxville
EYW - TYS
EYWTYS
Key West
Thu 12/10
6:00 pm-11:46 pm
1 stop5h 46m
Knoxville McGhee Tyson
Mon 12/14
3:55 pm-7:43 pm
1 stop3h 48m
$309
Key WestKnoxville
EYW - TYS
EYWTYS
Key West
Mon 12/7
7:00 am-1:23 pm
1 stop6h 23m
Knoxville McGhee Tyson
Mon 12/14
2:30 pm-7:43 pm
1 stop5h 13m
$309
Key WestKnoxville
EYW - TYS
EYWTYS
Key West
Thu 12/10
12:01 pm-8:27 am
2 stops20h 26m
Knoxville McGhee Tyson
Mon 12/14
11:00 am-1:12 pm
Nonstop2h 12m
$358
Key WestKnoxville
EYW - TYS
EYWTYS
Key West
Mon 12/7
7:00 am-2:29 pm
2 stops7h 29m
Knoxville McGhee Tyson
Mon 12/14
2:55 pm-11:07 pm
2 stops8h 12m
$747
Key WestKnoxville
EYW - TYS
EYWTYS
Key West
Mon 8/3
2:26 pm-10:42 am
2 stops20h 16m
Knoxville McGhee Tyson
Fri 8/7
7:19 pm-1:30 pm
2 stops18h 11m
$758
Cheapest one-way
Key WestKnoxville
EYW - TYS
EYWTYS
Key West
Mon 7/6
12:07 pm-11:33 pm
1 stop11h 26m
$187
Quickest one-way
Key WestKnoxville
EYW - TYS
EYWTYS
Key West
Mon 12/14
7:00 am-11:06 am
1 stop4h 06m
$269
Key WestKnoxville
EYW - TYS
EYWTYS
Key West
Mon 12/7
12:00 pm-4:33 pm
1 stop4h 33m
$269
Key WestKnoxville
EYW - TYS
EYWTYS
Key West
Tue 10/20
11:45 am-5:18 pm
1 stop5h 33m
$328
Key WestKnoxville
EYW - TYS
EYWTYS
Key West
Mon 7/6
4:41 pm-3:30 pm
3 stops22h 49m
$355
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from Key West to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Key West to Knoxville in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Key West-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Key West-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Key West-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Key West-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Key West-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Key West to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Key West with our price prediction graph.
EYW-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Key West to Knoxville
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated June 19, 2026.
Read reviews from past customers who have flown Allegiant Air from Key West to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
6.9
Boarding
7.6
Food
5.8
Overall
7.3
Crew
8.1
Entertainment
5.4
Reviews
1 / 20
10.0
ExcellentJeff,Jun 2026
DEN - TYS
Comfort
6.9
Boarding
7.6
Food
5.8
Overall
7.3
Crew
8.1
Entertainment
5.4
Reviews
1 / 20
10.0
ExcellentJeff,Jun 2026
DEN - TYS
Related info for your journey
Find useful and relevant information for your journey from Key West to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa
Oak Ridge
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Other flights to Knoxville
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Key West and Knoxville flights
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Other flights from Key West
Browse through other flights departing from Key West. Flights are based on user searches made on Cheapflights and were last updated on June 19, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Key West to Knoxville
Discover the top airline that operate flights from Key West to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 19, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$92 | Average$169 | FlexibilityNo cancel fee | On-time88% |