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$159+ Cheap flights from Jackson, MS to Knoxville (JAN - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/15. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — TYS
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Jackson to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Jackson (JAN) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2025.

Round-trip from

$317
(Delta)

One-way from

$159
(United Airlines)

Popular in

February

Cheapest in

July

Average price

$398
From Jackson-Evers Intl to Knoxville McGhee Tyson
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One-way flight from Jackson-Evers Intl to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 13% potential increase in price ($65 potential increase over avg. RT price).
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Cheapest flight prices on average. 7% potential price decrease ($30 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Jackson to Knoxville

Cheapest flights from Jackson to Knoxville
Explore the most affordable flight options available from Jackson to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/15:32 amJAN - TYS
1 stop3h 56mDelta
Tue 11/45:44 amTYS - JAN
1 stop4h 30mDelta
Deal found 9/14$317
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/136:43 pmJAN - TYS
1 stop4h 07mAmerican Airlines
Mon 10/208:37 pmTYS - JAN
1 stop4h 35mAmerican Airlines
Deal found 9/15$347
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/184:28 pmJAN - TYS
1 stop6h 25mAmerican Airlines
Sun 10/198:37 pmTYS - JAN
1 stop4h 35mAmerican Airlines
Deal found 9/16$356
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/212:34 pmJAN - TYS
1 stop6h 12mAmerican Airlines
Mon 10/68:37 pmTYS - JAN
1 stop4h 35mAmerican Airlines
Deal found 9/15$367
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/177:18 pmJAN - TYS
1 stop3h 28mDelta
Mon 10/208:10 pmTYS - JAN
1 stop3h 40mDelta
Deal found 9/16$390
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2011:30 amJAN - TYS
1 stop6h 35mAmerican Airlines
Sat 9/275:05 amTYS - JAN
1 stop5h 51mAmerican Airlines
Deal found 9/15$395
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/136:31 pmJAN - TYS
1 stop4h 26mAmerican Airlines
Mon 12/225:40 pmTYS - JAN
1 stop7h 32mAmerican Airlines
Deal found 9/17$441
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/267:19 pmJAN - TYS
1 stop3h 25mDelta
Mon 9/296:08 pmTYS - JAN
1 stop6h 09mDelta
Deal found 9/16$467
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/31:38 pmJAN - TYS
1 stop4h 27mAmerican Airlines
Mon 10/68:37 pmTYS - JAN
1 stop4h 35mAmerican Airlines
Deal found 9/16$476
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/237:18 pmJAN - TYS
1 stop3h 28mDelta
Sun 10/268:10 pmTYS - JAN
1 stop3h 40mDelta
Deal found 9/15$480
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/315:05 pmJAN - TYS
1 stop5h 39mUnited Airlines
Tue 11/48:26 amTYS - JAN
2 stops14h 33mUnited Airlines
Deal found 9/14$535

Cheapflights Fare Finder

 
Customize your flight search to find flights from Jackson to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Jackson to Knoxville that are best for you.

Fly from

Jackson

Fly to

Knoxville

Route

Depart

Return

Price

JacksonKnoxville

JAN - TYS

JANTYS

Jackson-Evers Intl

Sat 11/1

5:32 am-10:28 am

1 stop3h 56m

Knoxville McGhee Tyson

Tue 11/4

5:44 am-9:14 am

1 stop4h 30m

$317

JacksonKnoxville

JAN - TYS

JANTYS

Jackson-Evers Intl

Sat 10/18

4:28 pm-11:53 pm

1 stop6h 25m

Knoxville McGhee Tyson

Sun 10/19

8:37 pm-12:12 am

1 stop4h 35m

$356

JacksonKnoxville

JAN - TYS

JANTYS

Jackson-Evers Intl

Thu 10/2

12:34 pm-7:46 pm

1 stop6h 12m

Knoxville McGhee Tyson

Mon 10/6

8:37 pm-12:12 am

1 stop4h 35m

$367

JacksonKnoxville

JAN - TYS

JANTYS

Jackson-Evers Intl

Fri 10/17

7:18 pm-11:46 pm

1 stop3h 28m

Knoxville McGhee Tyson

Mon 10/20

8:10 pm-10:50 pm

1 stop3h 40m

$390

JacksonKnoxville

JAN - TYS

JANTYS

Jackson-Evers Intl

Sat 9/20

11:30 am-7:05 pm

1 stop6h 35m

Knoxville McGhee Tyson

Sat 9/27

5:05 am-9:56 am

1 stop5h 51m

$395

JacksonKnoxville

JAN - TYS

JANTYS

Jackson-Evers Intl

Sat 12/13

6:31 pm-11:57 pm

1 stop4h 26m

Knoxville McGhee Tyson

Mon 12/22

5:40 pm-12:12 am

1 stop7h 32m

$441

JacksonKnoxville

JAN - TYS

JANTYS

Jackson-Evers Intl

Fri 9/26

5:05 pm-11:43 pm

1 stop5h 38m

Knoxville McGhee Tyson

Sun 9/28

7:15 am-11:14 am

1 stop4h 59m

$467

JacksonKnoxville

JAN - TYS

JANTYS

Jackson-Evers Intl

Fri 9/26

7:19 pm-11:44 pm

1 stop3h 25m

Knoxville McGhee Tyson

Mon 9/29

6:08 pm-11:17 pm

1 stop6h 09m

$467

JacksonKnoxville

JAN - TYS

JANTYS

Jackson-Evers Intl

Thu 10/23

7:18 pm-11:46 pm

1 stop3h 28m

Knoxville McGhee Tyson

Sun 10/26

8:10 pm-10:50 pm

1 stop3h 40m

$480

JacksonKnoxville

JAN - TYS

JANTYS

Jackson-Evers Intl

Fri 10/31

5:05 pm-11:44 pm

1 stop5h 39m

Knoxville McGhee Tyson

Tue 11/4

8:26 am-9:59 pm

2 stops14h 33m

$535

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 11 results
1
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Best time to book a flight from Jackson to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Jackson with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Jackson to Knoxville

What is the cheapest month to book a flight from Jackson, Mississippi to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Jackson, Mississippi to Knoxville (average of $295). Flying from Jackson, Mississippi to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from JAN to TYS?

Find hourly flight availability from Jackson to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

It’s typically best to fly out from Jackson, Mississippi to Knoxville in the afternoon. Doing so could potentially save you 28% on the flight price compared to flying in the morning, which is usually more expensive.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated September 17, 2025.
See what other customers who have flown with Delta and American Airlines from Jackson to Knoxville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,961 reviews

Crew

8.5

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,961 reviews
Delta
8.0
Very good
7,961 reviews

Crew

8.5

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,961 reviews

Crew

8.5

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Jackson to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Jackson, Mississippi to Knoxville?

    Delta and American Airlines can get you from Jackson, Mississippi to Knoxville in just under 3h 56m. Your travel time can differ by up to 2h 29m. The distance from Jackson, Mississippi to Knoxville is about 424 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Jackson, Mississippi to Knoxville round-trip?

    According to our current data, Delta ($228), and American Airlines ($278) offers the cheapest pricing from Jackson, Mississippi to Knoxville. Delta is currently priced 47% below the average price you’ll pay for this route.

  • Can I find deals for flights from Jackson to Knoxville that include hotel bookings?

    Yes. In addition to deals on Jackson to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Jackson to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Jackson to Knoxville.

  • Can I find deals for business class flights from Jackson to Knoxville?

    Yes. Cheapflights offers flight deals from Jackson to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Jackson, Mississippi to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Jackson, Mississippi to Knoxville (average of $295). Flying from Jackson, Mississippi to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

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Top 2 airlines flying from Jackson to Knoxville

Discover the top 2 airlines that operate flights from Jackson to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$228Average$445FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$278Average$464FlexibilityNo cancel feeOn-time71%

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