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Knoxville

$151+ Cheap flights from Iowa to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/15. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — TYS
Aug 5 — Aug 121
Tue 8/5
Tue 8/12
1 adult, Economy
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Cheap flight deals from Iowa to Knoxville

Keep the following information in mind while searching for Iowa to Knoxville flight deals. Data was last updated July 31, 2025.

Round-trip from

$225
(FlightHub)

One-way from

$151
(Mytrip)

Popular in

March

Cheapest in

January

Average price

$313
From Iowa to Knoxville McGhee Tyson
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One-way flight from Iowa to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 13% potential increase in price ($56 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($15 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Iowa to Knoxville

Cheapest flights from Iowa to Knoxville
Explore the most affordable flight options available from Iowa to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

This FlightHub deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/147:40 pmOMA - TYS
1 stop23h 05mFrontier
Thu 9/188:40 pmTYS - OMA
1 stop24h 10mFrontier
Deal found 7/30$225
This Mytrip deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1210:55 amDSM - TYS
1 stop10h 19mAllegiant Air
Sun 11/169:00 amTYS - DSM
1 stop6h 01mAllegiant Air
Deal found 7/31$242
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/136:12 pmDSM - TYS
1 stop5h 09mAmerican Airlines
Sat 9/203:10 pmTYS - DSM
1 stop3h 59mAmerican Airlines
Deal found 7/30$248
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/287:15 amDSM - TYS
1 stop8h 21mDelta
Mon 9/16:36 amTYS - DSM
1 stop4h 31mDelta
Deal found 7/31$249
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/233:26 pmMLI - TYS
1 stop6h 37mAmerican Airlines
Sat 9/277:45 pmTYS - MLI
1 stop4h 25mAmerican Airlines
Deal found 7/31$249
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/55:56 pmCID - TYS
1 stop5h 25mAmerican Airlines
Mon 9/87:45 pmTYS - CID
1 stop4h 11mAmerican Airlines
Deal found 7/29$249
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1412:40 pmOMA - TYS
1 stop6h 56mDelta
Thu 10/238:10 pmTYS - OMA
1 stop4h 49mDelta
Deal found 7/31$249
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/297:10 amOMA - TYS
1 stop4h 21mAmerican Airlines
Tue 11/412:46 pmTYS - OMA
2 stops10h 51mAmerican Airlines
Deal found 7/30$254
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/155:20 pmMLI - TYS
1 stop4h 17mUnited Airlines
Tue 8/197:00 amTYS - MLI
1 stop4h 10mUnited Airlines
Deal found 7/31$259
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/153:18 pmOMA - TYS
1 stop6h 19mUnited Airlines
Sat 8/167:00 amTYS - OMA
1 stop4h 32mUnited Airlines
Deal found 7/30$259
This Mytrip deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/611:25 amDSM - TYS
1 stop8h 11mMultiple Airlines
Wed 10/83:20 pmTYS - DSM
2 stops19h 41mMultiple Airlines
Deal found 7/30$301
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1211:25 amDSM - TYS
2 stops11h 34mUnited Airlines
Fri 8/157:00 amTYS - DSM
1 stop4h 29mUnited Airlines
Deal found 7/29$337

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Iowa to Knoxville that are best for you.

Fly from

Iowa

Fly to

Knoxville

Route

Depart

Return

Price

OmahaKnoxville

OMA - TYS

OMATYS

Omaha Eppley Airfield

Sun 9/14

7:40 pm-7:45 pm

1 stop23h 05m

Knoxville McGhee Tyson

Thu 9/18

8:40 pm-7:50 pm

1 stop24h 10m

$225

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

Wed 11/12

10:55 am-10:14 pm

1 stop10h 19m

Knoxville McGhee Tyson

Sun 11/16

9:00 am-2:01 pm

1 stop6h 01m

$242

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

Sat 9/13

6:12 pm-12:21 am

1 stop5h 09m

Knoxville McGhee Tyson

Sat 9/20

3:10 pm-6:09 pm

1 stop3h 59m

$248

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

Thu 8/28

7:15 am-4:36 pm

1 stop8h 21m

Knoxville McGhee Tyson

Mon 9/1

6:36 am-10:07 am

1 stop4h 31m

$249

MolineKnoxville

MLI - TYS

MLITYS

Moline Quad-City

Tue 9/23

3:26 pm-11:03 pm

1 stop6h 37m

Knoxville McGhee Tyson

Sat 9/27

7:45 pm-11:10 pm

1 stop4h 25m

$249

OmahaKnoxville

OMA - TYS

OMATYS

Omaha Eppley Airfield

Tue 10/14

12:40 pm-8:36 pm

1 stop6h 56m

Knoxville McGhee Tyson

Thu 10/23

8:10 pm-11:59 pm

1 stop4h 49m

$249

Cedar RapidsKnoxville

CID - TYS

CIDTYS

Cedar Rapids

Fri 9/5

5:56 pm-12:21 am

1 stop5h 25m

Knoxville McGhee Tyson

Mon 9/8

7:45 pm-10:56 pm

1 stop4h 11m

$249

OmahaKnoxville

OMA - TYS

OMATYS

Omaha Eppley Airfield

Wed 10/29

7:10 am-12:31 pm

1 stop4h 21m

Knoxville McGhee Tyson

Tue 11/4

12:46 pm-10:37 pm

2 stops10h 51m

$254

MolineKnoxville

MLI - TYS

MLITYS

Moline Quad-City

Fri 8/15

5:20 pm-10:37 pm

1 stop4h 17m

Knoxville McGhee Tyson

Tue 8/19

7:00 am-10:10 am

1 stop4h 10m

$259

OmahaKnoxville

OMA - TYS

OMATYS

Omaha Eppley Airfield

Fri 8/15

3:18 pm-10:37 pm

1 stop6h 19m

Knoxville McGhee Tyson

Sat 8/16

7:00 am-10:32 am

1 stop4h 32m

$259

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/31

Showing 1-10 of 26 results
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2
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Best time to book a flight from Iowa to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Knoxville

What is the cheapest month to book a flight from Iowa to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Iowa to Knoxville (average of $294). Flying from Iowa to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to TYS?

Find hourly flight availability from Iowa to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 31, 2025.

When flying from Iowa to Knoxville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated July 31, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Iowa to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,981 reviews

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,981 reviews
Delta
8.0
Very good
7,981 reviews

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,900 reviews
Delta
8.0
Very good
7,981 reviews

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,981 reviews

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Allegiant Air
7.2
Good
702 reviews
Delta
8.0
Very good
7,981 reviews

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Frontier
5.9
Fair
3,239 reviews
Delta
8.0
Very good
7,981 reviews

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Iowa to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Iowa?

    Most people fly into Knoxville McGhee Tyson (TYS) if they book a flight to Knoxville from Iowa. McGhee Tyson is conveniently located just 11.3 mi from Knoxville’s city center.

  • What are the cheapest airlines to fly from Iowa to Knoxville one-way?

    The cheapest airlines for a one-way flight from Iowa to Knoxville are Allegiant Air ($151), American Airlines ($239), and United Airlines ($322).

  • What are the most popular routes from Iowa to Knoxville?

    The most popular flight routes from Iowa to Knoxville are Omaha Eppley Airfield - Knoxville McGhee Tyson, Cedar Rapids - Knoxville McGhee Tyson and Des Moines - Knoxville McGhee Tyson.

  • Can I find deals for flights from Iowa to Knoxville that include hotel bookings?

    Yes. In addition to deals on Iowa to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Knoxville.

  • Can I find deals for business class flights from Iowa to Knoxville?

    Yes. Cheapflights offers flight deals from Iowa to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Iowa to Knoxville (average of $294). Flying from Iowa to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

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Alternative routes for Iowa to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Iowa to Knoxville

Discover the top 3 airlines that operate flights from Iowa to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$208Average$345FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$248Average$455FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$248Average$350FlexibilityNo cancel feeOn-time71%

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