HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Knoxville

$52+ Cheap flights from Illinois to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/28. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — TYS
Apr 16 — Apr 231
Thu 4/16
Thu 4/23
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Illinois to Knoxville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Illinois to Knoxville

Cheapest flights from Illinois to Knoxville
Explore the most affordable flight options available from Illinois to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 17, 2026.

This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/141:27 pm
ORD
-
TYS
1 stop20h 09m
Multiple Airlines
Tue 4/213:48 pm
TYS
-
ORD
2 stops26h 12m
Multiple Airlines
Deal found 3/17$218
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:10 pm
ORD
-
TYS
1 stop26h 55m
Multiple Airlines
Wed 4/154:25 pm
TYS
-
ORD
1 stop29h 52m
Multiple Airlines
Deal found 3/13$219
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:24 pm
ORD
-
TYS
Nonstop1h 54m
American Airlines
Mon 4/138:48 pm
TYS
-
ORD
Nonstop2h 09m
American Airlines
Deal found 3/16$227
This American Airlines deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/118:30 am
ORD
-
TYS
Nonstop1h 48m
American Airlines
Mon 4/138:48 pm
TYS
-
ORD
Nonstop2h 09m
American Airlines
Deal found 3/14$228
This United Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/117:15 am
ORD
-
TYS
Nonstop1h 51m
United Airlines
Sat 4/187:00 am
TYS
-
ORD
Nonstop1h 55m
United Airlines
Deal found 3/13$229
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/282:47 pm
MDW
-
TYS
Nonstop1h 26m
Multiple Airlines
Sun 5/316:03 pm
TYS
-
MDW
2 stops21h 09m
Multiple Airlines
Deal found 3/15$229
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/179:16 am
MDW
-
TYS
1 stop9h 39m
Allegiant Air
Thu 5/211:22 pm
TYS
-
MDW
Nonstop1h 35m
Allegiant Air
Deal found 3/13$232
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/53:24 pm
STL
-
TYS
1 stop5h 02m
American Airlines
Tue 5/127:53 am
TYS
-
STL
1 stop4h 54m
American Airlines
Deal found 3/12$233
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:10 pm
ORD
-
TYS
1 stop26h 55m
Multiple Airlines
Thu 4/163:35 pm
TYS
-
ORD
1 stop9h 49m
Multiple Airlines
Deal found 3/13$234
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/229:30 pm
MDW
-
TYS
1 stop23h 48m
Allegiant Air
Sun 5/241:22 pm
TYS
-
MDW
Nonstop1h 35m
Allegiant Air
Deal found 3/15$236
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/299:30 pm
MDW
-
TYS
1 stop23h 48m
Allegiant Air
Sun 5/311:22 pm
TYS
-
MDW
Nonstop1h 35m
Allegiant Air
Deal found 3/16$237
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/912:00 pm
ORD
-
TYS
1 stop9h 05m
Multiple Airlines
Mon 4/136:20 pm
TYS
-
ORD
2 stops23h 40m
Multiple Airlines
Deal found 3/15$238

Find flight deals from Illinois to Knoxville

Keep the following information in mind while searching for Illinois to Knoxville flight deals. Data was last updated March 17, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$219
(Kiwi.com)

One-way from

$52
(Cheapflightsfares)

Popular in

March

Cheapest in

September

Average price

$344

Good round-trip deal

$106 or less

Good one-way deal

$168 or less
Provider with most accurate pricing for Chicago (CHI)-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Chicago (CHI)-Knoxville McGhee Tyson flights.
Search Deals
From Illinois to Knoxville McGhee Tyson
Search Deals
One-way flight from Illinois to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($37 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals
Price to beat on a round-trip flight from Illinois to Knoxville McGhee Tyson.
Search Deals
Price to beat on a one-way flight from Illinois to Knoxville McGhee Tyson.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Illinois to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 17, 2026.
Use the filters below to find and compare flights from Illinois to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Sat 6/13

6:07 pm-8:56 pm

Nonstop1h 49m

Knoxville McGhee Tyson

Wed 6/17

6:30 am-7:29 am

Nonstop1h 59m

$249

SpringfieldKnoxville

SPI - TYS

SPITYS

Springfield Capital

Mon 4/13

4:36 pm-2:58 pm

1 stop21h 22m

Knoxville McGhee Tyson

Fri 4/17

6:20 pm-9:26 am

1 stop16h 06m

$249

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Fri 5/8

2:05 pm-4:54 pm

Nonstop1h 49m

Knoxville McGhee Tyson

Sat 5/23

5:57 pm-6:59 pm

Nonstop2h 02m

$249

St. LouisKnoxville

STL - TYS

STLTYS

Lambert-St Louis

Mon 5/11

9:21 am-4:54 pm

1 stop6h 33m

Knoxville McGhee Tyson

Thu 5/14

6:01 pm-9:13 pm

1 stop4h 12m

$257

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Wed 4/15

5:55 am-5:10 pm

1 stop10h 15m

Knoxville McGhee Tyson

Sun 4/19

6:40 am-12:50 pm

1 stop7h 10m

$260

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Wed 5/27

6:07 pm-8:56 pm

Nonstop1h 49m

Knoxville McGhee Tyson

Sun 5/31

6:30 am-7:29 am

Nonstop1h 59m

$264

St. LouisKnoxville

STL - TYS

STLTYS

Lambert-St Louis

Mon 5/11

5:45 am-2:10 pm

1 stop7h 25m

Knoxville McGhee Tyson

Thu 5/14

6:35 am-2:55 pm

2 stops9h 20m

$268

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Wed 4/8

5:30 am-11:17 am

1 stop4h 47m

Knoxville McGhee Tyson

Tue 4/21

4:38 pm-8:16 pm

1 stop4h 38m

$269

St. LouisKnoxville

STL - TYS

STLTYS

Lambert-St Louis

Thu 4/9

9:55 am-8:20 pm

1 stop9h 25m

Knoxville McGhee Tyson

Thu 4/16

12:15 pm-6:10 pm

1 stop6h 55m

$272

PeoriaKnoxville

PIA - TYS

PIATYS

Greater Peoria

Sun 4/12

6:19 pm-12:53 pm

1 stop17h 34m

Knoxville McGhee Tyson

Fri 4/17

6:20 pm-9:38 am

1 stop16h 18m

$273

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/12

Showing 1-10 of 60 resultsSorted by cheapest first
1
2
3
...
6

Best time to book a flight from Illinois to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Illinois with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Illinois to Knoxville

What is the cheapest month to book a flight from Illinois to Knoxville?

Currently, July is the cheapest month in which you can book a flight from Illinois to Knoxville (average of $78). Flying from Illinois to Knoxville in December is currently the most expensive (average of $193). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IL to TYS?

Find hourly flight availability from Illinois to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 17, 2026.

When flying from Illinois to Knoxville, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 18% versus a flight at noon.

What is the cheapest day to fly from Illinois to Knoxville?

Use this chart to determine the cheapest time to fly round-trip from Illinois to Knoxville. Price data was last updated on October 19, 2025.

Travelers seeking maximum savings on their Illinois to Knoxville flight should consider departing on Thursday afternoons when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Illinois to Knoxville

Explore weekly flight availability from Illinois to Knoxville. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated March 17, 2026.

The most flights from USIL to TYS are scheduled on a Monday (23 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (15 on average).

Related info for your journey

Find useful and relevant information for your journey from Illinois to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Illinois?

    Knoxville McGhee Tyson (TYS), located 11.3 mi from the city center, is the airport you fly into when you book flights from Illinois to Knoxville.

  • How long is the flight from Illinois to Knoxville?

    A quick flight from Illinois to Knoxville can take about 1h 49m. United Airlines provides one of the quickest options available for as low as $249. The distance between Illinois and Knoxville is about 475 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Illinois to Knoxville one-way?

    The cheapest airlines for a one-way flight from Illinois to Knoxville are Allegiant Air ($47), American Airlines ($128), and United Airlines ($128).

  • What are the most popular routes from Illinois to Knoxville?

    While some choose either Chicago Midway - Knoxville McGhee Tyson or Lambert-St Louis - Knoxville McGhee Tyson, Chicago O'Hare Intl - Knoxville McGhee Tyson is the most popular route from Illinois to Knoxville.

  • What are the most reliable airlines from Illinois to Knoxville?

    No one likes to see their flight delayed. When booking a flight from Illinois to Knoxville consider choosing Air Canada (67%), SkyWest Airlines (65%) or ANA (65%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Illinois to Knoxville?

    While on average a flight from Illinois to Knoxville is generally $368, our data shows the cheapest flight currently is $138. When looking at the most popular route, (Chicago O'Hare Intl - Knoxville McGhee Tyson), you can expect to pay $249 for that flight.

  • Can I find deals for flights from Illinois to Knoxville that include hotel bookings?

    Yes. In addition to deals on Illinois to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Illinois to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Illinois to Knoxville.

  • Can I find deals for business class flights from Illinois to Knoxville?

    Yes. Cheapflights offers flight deals from Illinois to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Illinois to Knoxville?

    Currently, July is the cheapest month in which you can book a flight from Illinois to Knoxville (average of $78). Flying from Illinois to Knoxville in December is currently the most expensive (average of $193). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Murphy
Oak Ridge

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Illinois to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
Newark to Nashville flights
LaGuardia to Nashville flights
John F Kennedy Intl to Nashville flights
Boston to Nashville flights
Los Angeles to Nashville flights
O'Hare Intl to Nashville flights
Reagan-National to Nashville flights
Denver to Nashville flights
Philadelphia to Nashville flights
Dulles Intl to Nashville flights
Dallas/Fort Worth to Nashville flights
Minneapolis to Nashville flights
Baltimore to Nashville flights
San Francisco to Nashville flights
Seattle to Nashville flights
Hobby to Nashville flights
Detroit to Nashville flights
Raleigh to Nashville flights
LaGuardia to Knoxville flights
Ontario to Nashville flights
George Bush Intcntl to Nashville flights
Fort Lauderdale to Nashville flights
O'Hare Intl to Knoxville flights
Miami to Nashville flights
Charlotte to Nashville flights
Austin to Nashville flights
Providence to Nashville flights
John F Kennedy Intl to Knoxville flights
Orlando to Nashville flights
San Diego to Nashville flights
Sky Harbor Intl to Nashville flights
Salt Lake City to Nashville flights
Sacramento to Nashville flights
Tampa to Nashville flights
Hartford to Nashville flights
Cleveland to Nashville flights
Midway to Nashville flights
Santa Ana to Nashville flights
Burbank to Nashville flights
Portland to Nashville flights
Dallas/Fort Worth to Knoxville flights
Newark to Memphis flights
Baltimore to Memphis flights
West Palm Beach to Nashville flights
Albany to Nashville flights
LaGuardia to Memphis flights
Milwaukee to Nashville flights
Reagan-National to Memphis flights
Dulles Intl to Memphis flights
Hobby to Knoxville flights

Top 4 airlines flying from Illinois to Knoxville

Discover the top 4 airlines that operate flights from Illinois to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 17, 2026.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$80Average$158FlexibilityNo cancel feeOn-time88%
DeltaCheapest$138Average$240FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$188Average$347FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$189Average$338FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.