HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Knoxville

$51+ Cheap flights from Illinois to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/31. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — TYS
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Illinois to Knoxville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Illinois to Knoxville

Keep the following information in mind while searching for Illinois to Knoxville flight deals. Data was last updated September 11, 2025.

Round-trip from

$134
(Kiwi.com)

One-way from

$51
(Cheapflightsfares)

Popular in

December

Cheapest in

September

Average price

$223

Good round-trip deal

$91 or less

Good one-way deal

$58 or less
From Illinois to Knoxville McGhee Tyson
Search Deals
One-way flight from Illinois to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($6 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals
Price to beat on a round-trip flight from Illinois to Knoxville McGhee Tyson.
Search Deals
Price to beat on a one-way flight from Illinois to Knoxville McGhee Tyson.
Search Deals

Find flight deals from Illinois to Knoxville

Cheapest flights from Illinois to Knoxville
Explore the most affordable flight options available from Illinois to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2710:51 amORD - TYS
1 stop7h 41mFrontier
Thu 10/307:17 pmTYS - ORD
1 stop29h 59mFrontier
Deal found 9/10$134
This Cheapflightsfares deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/127:50 pmMDW - TYS
Nonstop1h 31mAllegiant Air
Fri 9/196:24 pmTYS - MDW
Nonstop1h 36mAllegiant Air
Deal found 9/11$136
This Trip.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/197:50 pmMDW - TYS
Nonstop1h 31mAllegiant Air
Mon 9/226:24 pmTYS - MDW
Nonstop1h 36mAllegiant Air
Deal found 9/10$141
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/127:50 pmMDW - TYS
Nonstop1h 31mAllegiant Air
Mon 9/156:24 pmTYS - MDW
Nonstop1h 36mAllegiant Air
Deal found 9/10$146
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/293:16 pmMDW - TYS
Nonstop1h 31mAllegiant Air
Fri 10/310:44 amTYS - MDW
Nonstop1h 32mAllegiant Air
Deal found 9/9$156
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/104:12 pmMDW - TYS
Nonstop1h 25mMultiple Airlines
Thu 11/137:17 pmTYS - MDW
1 stop17h 13mMultiple Airlines
Deal found 9/9$165
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/116:00 amSTL - TYS
1 stop5h 43mAmerican Airlines
Sat 11/155:10 amTYS - STL
1 stop6h 29mAmerican Airlines
Deal found 9/10$165
This Cheapflightsfares deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1712:06 pmMDW - TYS
Nonstop1h 24mAllegiant Air
Mon 10/2010:46 amTYS - MDW
Nonstop1h 32mAllegiant Air
Deal found 9/9$172
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/293:16 pmMDW - TYS
Nonstop1h 31mAllegiant Air
Wed 10/112:15 pmTYS - MDW
1 stop28h 41mAllegiant Air
Deal found 9/10$173
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/32:45 pmMDW - TYS
Nonstop1h 24mMultiple Airlines
Mon 11/105:22 pmTYS - MDW
2 stops44h 19mMultiple Airlines
Deal found 9/10$176
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/267:50 pmMDW - TYS
Nonstop1h 31mAllegiant Air
Wed 10/112:15 pmTYS - MDW
1 stop28h 41mAllegiant Air
Deal found 9/10$177
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/278:24 pmMDW - TYS
Nonstop1h 24mMultiple Airlines
Thu 10/306:51 pmTYS - MDW
1 stop14h 41mMultiple Airlines
Deal found 9/10$178

Cheapflights Fare Finder

 
Customize your flight search to find flights from Illinois to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Illinois to Knoxville that are best for you.

Fly from

Illinois

Fly to

Knoxville

Route

Depart

Return

Price

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Fri 11/7

2:57 pm-5:22 pm

Nonstop1h 25m

Knoxville McGhee Tyson

Mon 11/10

5:22 pm-12:41 pm

2 stops44h 19m

$183

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Wed 10/15

2:28 pm-5:18 pm

Nonstop1h 50m

Knoxville McGhee Tyson

Sun 10/19

5:53 pm-6:55 pm

Nonstop2h 02m

$189

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Fri 11/14

5:50 pm-8:33 pm

Nonstop1h 43m

Knoxville McGhee Tyson

Sun 11/16

6:45 am-7:46 am

Nonstop2h 01m

$189

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Fri 9/26

8:00 pm-10:50 pm

Nonstop1h 50m

Knoxville McGhee Tyson

Mon 9/29

7:00 am-7:55 am

Nonstop1h 55m

$199

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Fri 9/26

8:00 pm-10:50 pm

Nonstop1h 50m

Knoxville McGhee Tyson

Tue 9/30

7:00 am-7:55 am

Nonstop1h 55m

$199

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Mon 10/27

8:24 pm-10:48 pm

Nonstop1h 24m

Knoxville McGhee Tyson

Thu 10/30

7:17 pm-11:30 am

1 stop17h 13m

$204

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Fri 9/26

7:50 pm-10:21 pm

Nonstop1h 31m

Knoxville McGhee Tyson

Mon 9/29

12:45 pm-11:20 pm

2 stops11h 35m

$206

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Mon 11/10

4:12 pm-6:37 pm

Nonstop1h 25m

Knoxville McGhee Tyson

Thu 11/13

9:00 am-10:03 pm

2 stops14h 03m

$208

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Fri 11/7

2:57 pm-5:22 pm

Nonstop1h 25m

Knoxville McGhee Tyson

Sun 11/9

1:16 pm-11:30 am

2 stops23h 14m

$208

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Tue 11/18

11:14 am-7:00 pm

1 stop6h 46m

Knoxville McGhee Tyson

Sat 11/22

3:51 pm-6:47 pm

1 stop3h 56m

$209

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/9

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Illinois to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Illinois with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Illinois to Knoxville

What is the cheapest month to book a flight from Illinois to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Illinois to Knoxville (average of $294). Flying from Illinois to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IL to TYS?

Find hourly flight availability from Illinois to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Illinois to Knoxville as you normally would.

Weekly flight availability from Illinois to Knoxville

Explore weekly flight availability from Illinois to Knoxville. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 11, 2025.

The most flights from USIL to TYS are scheduled on a Wednesday (27 on average). You will have fewer flight options on Friday, which is when the least amount of flights are scheduled (20 on average).

Related info for your journey

Find useful and relevant information for your journey from Illinois to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Illinois?

    Knoxville McGhee Tyson (TYS), located 11.3 mi from the city center, is the airport you fly into when you book flights from Illinois to Knoxville.

  • How long is the flight from Illinois to Knoxville?

    A quick flight from Illinois to Knoxville can take about 1h 50m. United Airlines provides one of the quickest options available for as low as $189. The distance between Illinois and Knoxville is about 475 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Illinois to Knoxville one-way?

    The cheapest airlines for a one-way flight from Illinois to Knoxville are Allegiant Air ($51), Frontier ($76), and American Airlines ($83).

  • What are the most popular routes from Illinois to Knoxville?

    While some choose either Lambert-St Louis - Knoxville McGhee Tyson or Chicago Midway - Knoxville McGhee Tyson, Chicago O'Hare Intl - Knoxville McGhee Tyson is the most popular route from Illinois to Knoxville.

  • What are the most reliable airlines from Illinois to Knoxville?

    No one likes to see their flight delayed. When booking a flight from Illinois to Knoxville consider choosing SkyWest Airlines (88%), Envoy Air (79%) or ANA (78%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Illinois to Knoxville?

    While on average a flight from Illinois to Knoxville is generally $315, our data shows the cheapest flight currently is $128. When looking at the most popular route, (Chicago O'Hare Intl - Knoxville McGhee Tyson), you can expect to pay $189 for that flight.

  • Can I find deals for flights from Illinois to Knoxville that include hotel bookings?

    Yes. In addition to deals on Illinois to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Illinois to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Illinois to Knoxville.

  • Can I find deals for business class flights from Illinois to Knoxville?

    Yes. Cheapflights offers flight deals from Illinois to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Illinois to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Illinois to Knoxville (average of $294). Flying from Illinois to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Illinois to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Nashville flights
LaGuardia to Nashville flights
Newark to Nashville flights
Boston to Nashville flights
Seattle to Nashville flights
Los Angeles to Nashville flights
O'Hare Intl to Nashville flights
Reagan-National to Nashville flights
Philadelphia to Nashville flights
Hobby to Nashville flights
Dallas/Fort Worth to Nashville flights
Denver to Nashville flights
Dulles Intl to Nashville flights
Ontario to Nashville flights
Raleigh to Nashville flights
San Francisco to Nashville flights
George Bush Intcntl to Nashville flights
Newark to Memphis flights
LaGuardia to Memphis flights
John F Kennedy Intl to Memphis flights
Baltimore to Nashville flights
Fort Lauderdale to Nashville flights
Providence to Nashville flights
Santa Ana to Nashville flights
Minneapolis to Nashville flights
Detroit to Nashville flights
LaGuardia to Knoxville flights
Burbank to Nashville flights
O'Hare Intl to Knoxville flights
Miami to Nashville flights
Midway to Nashville flights
Portland to Nashville flights
Hartford to Nashville flights
Orlando to Nashville flights
Dallas/Fort Worth to Knoxville flights
Tampa to Nashville flights
John F Kennedy Intl to Knoxville flights
Sky Harbor Intl to Nashville flights
Charlotte to Nashville flights
Dallas/Fort Worth to Memphis flights
Love Field to Nashville flights
George Bush Intcntl to Knoxville flights
Cleveland to Nashville flights
Denver to Knoxville flights
O'Hare Intl to Memphis flights
San Diego to Nashville flights
Pittsburgh to Nashville flights
Sacramento to Nashville flights
Los Angeles to Memphis flights
Austin to Nashville flights

Top 4 airlines flying from Illinois to Knoxville

Discover the top 4 airlines that operate flights from Illinois to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$77Average$122FlexibilityNo cancel feeOn-time88%
American AirlinesCheapest$179Average$348FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$190Average$353FlexibilityNo cancel feeOn-time69%
DeltaCheapest$193Average$342FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.