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$234+ Cheap flights from Ecuador to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/5. Fares are subject to change and may not be available on all flights or dates of travel.
UIO — TYS
sep. 2 — sep. 91
mar. 9/2
mar. 9/9
1 adult, Economy
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Cheap flight deals from Ecuador to Knoxville

Keep the following information in mind while searching for Ecuador to Knoxville flight deals. Data was last updated agosto 28, 2025.

Round-trip from

$448
(Kiwi.com)

One-way from

$234
(eDestinos)
From Ecuador to Knoxville McGhee Tyson
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One-way flight from Ecuador to Knoxville McGhee Tyson
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Find flight deals from Ecuador to Knoxville

Cheapest flights from Ecuador to Knoxville
Explore the most affordable flight options available from Ecuador to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on agosto 28, 2025.

This Kiwi.com deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/34:40 amGYE - TYS
2 stops35h 02mMultiple Airlines
dom. 12/77:11 pmTYS - GYE
1 stop28h 34mMultiple Airlines
Deal found 8/26$427
This Kiwi.com deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/43:30 amGYE - TYS
2 stops29h 34mMultiple Airlines
dom. 12/77:11 pmTYS - GYE
1 stop28h 34mMultiple Airlines
Deal found 8/26$434
This Kiwi.com deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/24:40 amGYE - TYS
2 stops29h 53mMultiple Airlines
dom. 12/77:11 pmTYS - GYE
1 stop28h 34mMultiple Airlines
Deal found 8/26$435
This Kiwi.com deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/76:02 amGYE - TYS
2 stops28h 02mMultiple Airlines
dom. 12/77:11 pmTYS - GYE
1 stop28h 34mMultiple Airlines
Deal found 8/28$448
This Kiwi.com deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/34:40 amGYE - TYS
2 stops35h 02mMultiple Airlines
lun. 12/89:23 amTYS - GYE
1 stop14h 22mMultiple Airlines
Deal found 8/26$477
This Kiwi.com deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/86:55 pmGYE - TYS
2 stops27h 38mMultiple Airlines
dom. 12/77:11 pmTYS - GYE
1 stop28h 34mMultiple Airlines
Deal found 8/26$478
This Kiwi.com deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/24:40 amGYE - TYS
2 stops29h 53mMultiple Airlines
lun. 12/89:23 amTYS - GYE
1 stop14h 22mMultiple Airlines
Deal found 8/26$485
This Kiwi.com deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/76:02 amGYE - TYS
2 stops28h 02mMultiple Airlines
lun. 12/89:23 amTYS - GYE
1 stop14h 22mMultiple Airlines
Deal found 8/26$498
This Kiwi.com deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/34:40 amGYE - TYS
2 stops35h 02mMultiple Airlines
mié. 12/1012:53 pmTYS - GYE
1 stop10h 52mMultiple Airlines
Deal found 8/26$517
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/1912:54 amUIO - TYS
2 stops14h 53mAmerican Airlines
sáb. 1/35:00 amTYS - UIO
2 stops17h 18mAmerican Airlines
Deal found 8/27$825
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/208:00 amUIO - TYS
1 stop15h 42mUnited Airlines
sáb. 1/311:00 amTYS - UIO
2 stops19h 10mUnited Airlines
Deal found 8/27$855

Cheapflights Fare Finder

 
Customize your flight search to find flights from Ecuador to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 28, 2025.
Use the filters below to find and compare flights from Ecuador to Knoxville that are best for you.

Fly from

Ecuador

Fly to

Knoxville

Route

Depart

Return

Price

GuayaquilKnoxville

GYE - TYS

GYETYS

Guayaquil Jose Joaquin de Olmedo

vie. 11/7

6:02 am-10:04 am

2 stops28h 02m

Knoxville McGhee Tyson

dom. 12/7

7:11 pm-11:45 pm

1 stop28h 34m

$448

GuayaquilKnoxville

GYE - TYS

GYETYS

Guayaquil Jose Joaquin de Olmedo

mar. 11/4

3:30 am-9:04 am

2 stops29h 34m

Knoxville McGhee Tyson

dom. 12/7

7:11 pm-11:45 pm

1 stop28h 34m

$479

GuayaquilKnoxville

GYE - TYS

GYETYS

Guayaquil Jose Joaquin de Olmedo

vie. 11/7

6:02 am-10:04 am

2 stops28h 02m

Knoxville McGhee Tyson

lun. 12/8

9:23 am-11:45 pm

1 stop14h 22m

$511

GuayaquilKnoxville

GYE - TYS

GYETYS

Guayaquil Jose Joaquin de Olmedo

mar. 11/4

3:30 am-9:04 am

2 stops29h 34m

Knoxville McGhee Tyson

lun. 12/8

9:23 am-11:45 pm

1 stop14h 22m

$542

GuayaquilKnoxville

GYE - TYS

GYETYS

Guayaquil Jose Joaquin de Olmedo

jue. 11/6

6:55 pm-10:26 pm

2 stops27h 31m

Knoxville McGhee Tyson

lun. 12/8

9:23 am-11:45 pm

1 stop14h 22m

$549

GuayaquilKnoxville

GYE - TYS

GYETYS

Guayaquil Jose Joaquin de Olmedo

jue. 2/19

12:20 pm-7:34 pm

2 stops31h 14m

Knoxville McGhee Tyson

jue. 5/14

7:00 am-11:17 am

2 stops29h 17m

$596

GuayaquilKnoxville

GYE - TYS

GYETYS

Guayaquil Jose Joaquin de Olmedo

mié. 11/5

12:21 pm-6:04 pm

2 stops29h 43m

Knoxville McGhee Tyson

mié. 12/10

7:05 am-11:41 pm

2 stops16h 36m

$596

GuayaquilKnoxville

GYE - TYS

GYETYS

Guayaquil Jose Joaquin de Olmedo

mié. 2/18

12:59 am-8:42 pm

1 stop19h 43m

Knoxville McGhee Tyson

jue. 5/14

11:27 am-10:40 pm

2 stops12h 13m

$607

GuayaquilKnoxville

GYE - TYS

GYETYS

Guayaquil Jose Joaquin de Olmedo

sáb. 11/8

9:05 am-9:04 am

2 stops23h 59m

Knoxville McGhee Tyson

dom. 12/7

7:11 pm-11:45 pm

1 stop28h 34m

$610

GuayaquilKnoxville

GYE - TYS

GYETYS

Guayaquil Jose Joaquin de Olmedo

vie. 11/7

6:02 am-10:04 am

2 stops28h 02m

Knoxville McGhee Tyson

mié. 12/10

12:53 pm-11:45 pm

1 stop10h 52m

$653

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/27

Showing 1-10 of 20 results
1
2

Best time to book a flight from Ecuador to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Ecuador with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ecuador to Knoxville

What is the cheapest time of day to fly from EC to TYS?

Find hourly flight availability from Ecuador to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated agosto 28, 2025.

When flying from Ecuador to Knoxville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated agosto 28, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Ecuador to Knoxville by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,977 reviews

Overall

8.0

Entertainment

7.9

Food

7.3

Boarding

8.2

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others
Delta
8.0
Very good
7,977 reviews
Delta
8.0
Very good
7,977 reviews

Overall

8.0

Entertainment

7.9

Food

7.3

Boarding

8.2

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others
United Airlines
7.4
Good
8,944 reviews
Delta
8.0
Very good
7,977 reviews

Overall

8.0

Entertainment

7.9

Food

7.3

Boarding

8.2

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,977 reviews

Overall

8.0

Entertainment

7.9

Food

7.3

Boarding

8.2

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others

Related info for your journey

Find useful and relevant information for your journey from Ecuador to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Ecuador?

    If you book a flight to Knoxville from Ecuador, you will be flying to McGhee Tyson, which is the city’s only airport. Knoxville McGhee Tyson (TYS) is located 11.3 mi from the center of Knoxville.

  • How long is the flight from Ecuador to Knoxville?

    There are many flights that can get you from Ecuador to Knoxville in 14h 53m. Fly via American Airlines or United Airlines to get the fastest option. The distance between Ecuador and Knoxville is about 2507 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Ecuador to Knoxville that include hotel bookings?

    Yes. In addition to deals on Ecuador to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ecuador to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ecuador to Knoxville.

  • Can I find deals for business class flights from Ecuador to Knoxville?

    Yes. Cheapflights offers flight deals from Ecuador to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Ecuador to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Ecuador to Knoxville (average of $295). Flying from Ecuador to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

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Top 3 airlines flying from Ecuador to Knoxville

Discover the top 3 airlines that operate flights from Ecuador to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$388Average$654FlexibilityNo cancel feeOn-time69%
DeltaCheapest$622Average$786FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$720Average$852FlexibilityNo cancel feeOn-time71%

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