Knoxville

$255+ Cheap flights from Ecuador to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/18. Fares are subject to change and may not be available on all flights or dates of travel.
UIO — TYS
Nov 25 — Dec 21
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Cheap flight deals from Ecuador to Knoxville

Keep the following information in mind while searching for Ecuador to Knoxville flight deals. Data was last updated October 26, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$639
(Kiwi.com)

One-way from

$255
(eDestinos)
Provider with most accurate pricing for Guayaquil Jose Joaquin de Olmedo-Knoxville McGhee Tyson flight deals.
Provider most trusted by Cheapflights users for Guayaquil Jose Joaquin de Olmedo-Knoxville McGhee Tyson flights.
From Ecuador to Knoxville McGhee Tyson
One-way flight from Ecuador to Knoxville McGhee Tyson

Find flight deals from Ecuador to Knoxville

Cheapest flights from Ecuador to Knoxville
Explore the most affordable flight options available from Ecuador to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 26, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1912:49 amGYE - TYS
1 stop19h 44mMultiple Airlines
Fri 1/25:46 pmTYS - GYE
2 stops54h 12mMultiple Airlines
Deal found 10/23$639
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/241:35 amUIO - TYS
2 stops42h 45mUnited Airlines
Thu 12/47:25 pmTYS - UIO
2 stops29h 05mUnited Airlines
Deal found 10/25$654
This eDestinos deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/257:05 amUIO - TYS
3 stops39h 04mMultiple Airlines
Thu 12/46:30 amTYS - UIO
3 stops46h 47mMultiple Airlines
Deal found 10/25$708
This Mytrip deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/243:15 amGYE - TYS
2 stops19h 37mMultiple Airlines
Fri 10/318:15 amTYS - GYE
3 stops26h 00mMultiple Airlines
Deal found 10/24$749
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/259:11 amUIO - TYS
2 stops24h 26mDelta
Thu 12/43:57 pmTYS - UIO
2 stops13h 20mDelta
Deal found 10/25$764
This Mytrip deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/243:15 amGYE - TYS
2 stops16h 56mAvianca
Fri 10/315:45 amTYS - GYE
2 stops18h 50mAvianca
Deal found 10/24$769
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/82:35 pmGYE - TYS
2 stops33h 09mUnited Airlines
Wed 12/107:05 amTYS - GYE
2 stops34h 31mUnited Airlines
Deal found 10/24$809
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/258:27 amUIO - TYS
1 stop15h 32mAmerican Airlines
Thu 12/46:00 amTYS - UIO
1 stop17h 02mAmerican Airlines
Deal found 10/25$1,318
This Booking.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2511:30 amUIO - TYS
3 stops32h 50mAvianca
Thu 12/47:25 pmTYS - UIO
2 stops24h 40mAvianca
Deal found 10/25$4,580

Cheapflights Fare Finder

 
Customize your flight search to find flights from Ecuador to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 26, 2025.
Use the filters below to find and compare flights from Ecuador to Knoxville that are best for you.

Fly from

Ecuador

Fly to

Knoxville

Route

Depart

Return

Price

GuayaquilKnoxville

GYE - TYS

GYETYS

Guayaquil Jose Joaquin de Olmedo

Fri 12/19

12:49 am-8:33 pm

1 stop19h 44m

Knoxville McGhee Tyson

Fri 1/2

5:46 pm-11:58 pm

2 stops54h 12m

$639

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Mon 11/24

1:35 am-8:20 pm

2 stops42h 45m

Knoxville McGhee Tyson

Thu 12/4

7:25 pm-12:30 am

2 stops29h 05m

$654

GuayaquilKnoxville

GYE - TYS

GYETYS

Guayaquil Jose Joaquin de Olmedo

Mon 3/2

7:11 am-11:59 pm

1 stop16h 48m

Knoxville McGhee Tyson

Sat 5/16

7:15 am-1:33 pm

1 stop7h 18m

$704

GuayaquilKnoxville

GYE - TYS

GYETYS

Guayaquil Jose Joaquin de Olmedo

Wed 2/18

7:35 am-5:35 pm

1 stop10h 00m

Knoxville McGhee Tyson

Wed 4/1

7:00 pm-1:33 pm

1 stop19h 33m

$704

GuayaquilKnoxville

GYE - TYS

GYETYS

Guayaquil Jose Joaquin de Olmedo

Mon 2/16

2:33 pm-5:35 pm

1 stop27h 02m

Knoxville McGhee Tyson

Thu 5/7

7:15 am-8:55 pm

1 stop14h 40m

$704

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Tue 11/25

7:05 am-10:09 pm

3 stops39h 04m

Knoxville McGhee Tyson

Thu 12/4

6:30 am-5:17 am

3 stops46h 47m

$708

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Sun 1/11

6:35 pm-5:28 pm

3 stops22h 53m

Knoxville McGhee Tyson

Fri 1/16

9:30 am-2:50 am

2 stops17h 20m

$733

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Tue 11/25

9:11 am-8:06 pm

2 stops10h 55m

Knoxville McGhee Tyson

Thu 12/4

5:40 am-8:00 pm

1 stop14h 20m

$764

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Sun 1/11

7:00 pm-11:44 pm

2 stops28h 44m

Knoxville McGhee Tyson

Fri 1/16

4:00 pm-8:00 pm

1 stop28h 00m

$991

GuayaquilKnoxville

GYE - TYS

GYETYS

Guayaquil Jose Joaquin de Olmedo

Wed 2/18

6:55 pm-8:42 pm

2 stops25h 47m

$255

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/25

Showing 1-10 of 18 results
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Best time to book a flight from Ecuador to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Ecuador with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ecuador to Knoxville

What is the cheapest time of day to fly from EC to TYS?

Find hourly flight availability from Ecuador to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 26, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 14% on flights from Ecuador to Knoxville by exploring options for tickets in the afternoon.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated October 26, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Ecuador to Knoxville by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

7.9

Boarding

8.2

Overall

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Mary,Oct 2025

AMS - PDX

It's specail being able to fly non-stop from Amsterdam all the way home to Portland, Oregon!

Entertainment

7.9

Boarding

8.2

Overall

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Mary,Oct 2025

AMS - PDX

It's specail being able to fly non-stop from Amsterdam all the way home to Portland, Oregon!

Entertainment

7.9

Boarding

8.2

Overall

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Mary,Oct 2025

AMS - PDX

It's specail being able to fly non-stop from Amsterdam all the way home to Portland, Oregon!

Entertainment

7.9

Boarding

8.2

Overall

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Mary,Oct 2025

AMS - PDX

It's specail being able to fly non-stop from Amsterdam all the way home to Portland, Oregon!

Related info for your journey

Find useful and relevant information for your journey from Ecuador to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Knoxville from Ecuador?

    If you book a flight to Knoxville from Ecuador, you will be flying to McGhee Tyson, which is the city’s only airport. Knoxville McGhee Tyson (TYS) is located 11.3 mi from the center of Knoxville.

  • How long is the flight from Ecuador to Knoxville?

    There are many flights that can get you from Ecuador to Knoxville in 16h 48m. Fly via United Airlines or American Airlines to get the fastest option. The distance between Ecuador and Knoxville is about 2635 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Ecuador to Knoxville that include hotel bookings?

    Yes. In addition to deals on Ecuador to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ecuador to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ecuador to Knoxville.

  • Can I find deals for business class flights from Ecuador to Knoxville?

    Yes. Cheapflights offers flight deals from Ecuador to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Crossville
Corbin
Bryson City
Alcoa
Oak Ridge
Murphy

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Top 3 airlines flying from Ecuador to Knoxville

Discover the top 3 airlines that operate flights from Ecuador to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$388Average$647FlexibilityNo cancel feeOn-time69%
DeltaCheapest$622Average$789FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$720Average$852FlexibilityNo cancel feeOn-time71%

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