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$149+ Cheap flights from Midway (MDW) to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/24. Fares are subject to change and may not be available on all flights or dates of travel.
MDW — TYS
Feb 20 — Feb 271
Fri 2/20
Fri 2/27
1 adult, Economy
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Cheap flight deals from Midway to Knoxville

Cheapest flights from Midway to Knoxville
Explore the most affordable flight options available from Midway to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/162:48 pm
MDW
-
TYS
Nonstop1h 30m
Allegiant Air
Sun 7/191:22 pm
TYS
-
MDW
Nonstop1h 36m
Allegiant Air
Deal found 1/20$160
This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/232:48 pm
MDW
-
TYS
Nonstop1h 30m
Allegiant Air
Sun 7/261:22 pm
TYS
-
MDW
Nonstop1h 36m
Allegiant Air
Deal found 1/19$175
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/144:13 pm
MDW
-
TYS
1 stop6h 39m
Delta
Sun 2/157:38 am
TYS
-
MDW
1 stop6h 08m
Delta
Deal found 1/20$209
This Southwest deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2910:05 am
MDW
-
TYS
2 stops8h 35m
Southwest
Sat 5/23:55 pm
TYS
-
MDW
1 stop6h 10m
Southwest
Deal found 1/20$214
This Southwest deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/511:35 am
MDW
-
TYS
1 stop8h 40m
Southwest
Mon 3/97:25 pm
TYS
-
MDW
1 stop5h 40m
Southwest
Deal found 1/20$215
This Southwest deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2910:15 am
MDW
-
TYS
2 stops8h 25m
Southwest
Tue 5/57:05 am
TYS
-
MDW
2 stops9h 20m
Southwest
Deal found 1/20$219
This Southwest deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/119:10 am
MDW
-
TYS
1 stop8h 20m
Southwest
Wed 4/1512:50 pm
TYS
-
MDW
2 stops8h 10m
Southwest
Deal found 1/19$220
This Delta deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/66:14 pm
MDW
-
TYS
1 stop4h 31m
Delta
Fri 2/136:41 pm
TYS
-
MDW
1 stop4h 50m
Delta
Deal found 1/19$224
This Southwest deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/510:15 am
MDW
-
TYS
2 stops9h 35m
Southwest
Sat 5/96:40 am
TYS
-
MDW
2 stops11h 30m
Southwest
Deal found 1/20$225
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/56:00 am
MDW
-
TYS
1 stop4h 17m
Delta
Sat 4/115:40 am
TYS
-
MDW
1 stop5h 16m
Delta
Deal found 1/21$234
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/46:00 am
MDW
-
TYS
1 stop4h 08m
Delta
Sat 2/75:40 am
TYS
-
MDW
1 stop5h 13m
Delta
Deal found 1/21$239

Find flight deals from Midway to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Midway (MDW) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 21, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$160
(Kiwi.com)

One-way from

$149
(Delta)

Popular in

April

Cheapest in

September

Average price

$271
Provider with most accurate pricing for Chicago Midway-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Chicago Midway-Knoxville McGhee Tyson flights.
Search Deals
From Chicago Midway to Knoxville McGhee Tyson
Search Deals
One-way flight from Chicago Midway to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 28% potential increase in price ($79 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Midway to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
Use the filters below to find and compare flights from Chicago Midway Airport to Knoxville that are best for you.

Fly from

Midway

Fly to

Knoxville

Route

Depart

Return

Price

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Sat 2/14

4:13 pm-11:52 pm

1 stop6h 39m

Knoxville McGhee Tyson

Sun 2/15

7:38 am-12:46 pm

1 stop6h 08m

$209

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Tue 2/17

6:40 pm-11:52 pm

1 stop4h 12m

Knoxville McGhee Tyson

Tue 2/24

5:35 am-9:54 am

1 stop5h 19m

$209

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Sat 4/11

9:10 am-6:30 pm

1 stop8h 20m

Knoxville McGhee Tyson

Wed 4/15

5:50 pm-10:15 pm

1 stop5h 25m

$215

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Fri 2/6

6:14 pm-11:45 pm

1 stop4h 31m

Knoxville McGhee Tyson

Fri 2/13

1:00 pm-5:37 pm

1 stop5h 37m

$224

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Sun 4/5

6:00 am-11:17 am

1 stop4h 17m

Knoxville McGhee Tyson

Sat 4/11

5:40 am-9:56 am

1 stop5h 16m

$234

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Wed 2/4

6:00 am-11:08 am

1 stop4h 08m

Knoxville McGhee Tyson

Sat 2/7

5:40 am-9:53 am

1 stop5h 13m

$239

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Fri 3/6

7:55 am-12:45 pm

1 stop3h 50m

Knoxville McGhee Tyson

Mon 3/9

7:25 pm-12:05 am

1 stop5h 40m

$253

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Fri 1/30

1:26 pm-8:47 pm

1 stop6h 21m

Knoxville McGhee Tyson

Mon 2/2

7:30 am-12:46 pm

1 stop6h 16m

$269

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Sat 1/31

10:46 am-3:19 pm

1 stop3h 33m

Knoxville McGhee Tyson

Sat 2/7

7:30 am-12:46 pm

1 stop6h 16m

$269

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Fri 2/6

6:14 pm-11:45 pm

1 stop4h 31m

Knoxville McGhee Tyson

Sun 2/8

5:40 am-9:53 am

1 stop5h 13m

$269

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/20

Showing 1-10 of 19 results
1
2

Compare providers for flights from Midway to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Midway to Knoxville in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Chicago Midway Airport-Knoxville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Chicago Midway Airport-Knoxville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Chicago Midway Airport-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Chicago Midway Airport-Knoxville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago Midway Airport-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Midway to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Midway with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago Midway Airport to Knoxville

What is the cheapest time of day to fly from MDW to TYS?

Find hourly flight availability from Midway to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 21, 2026.

A simple way to save on the total cost of your ticket is to fly from Chicago Midway Airport to Knoxville in the evening. If you’re flexible enough to do this you can expect to save up to 32% on your trip compared to booking a flight in the morning.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated January 21, 2026.
Read through reviews of airlines operating flights from Chicago Midway Airport to Knoxville, such as Delta and Allegiant Air. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,086 reviews

Crew

8.5

Food

7.2

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,086 reviews
Delta
7.9
Good
8,086 reviews

Crew

8.5

Food

7.2

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Allegiant Air
7.2
Good
705 reviews
Delta
7.9
Good
8,086 reviews

Crew

8.5

Food

7.2

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Midway to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Chicago Midway?

    If you book a flight to Knoxville from Chicago Midway, you will be flying to McGhee Tyson, which is the city’s only airport. Knoxville McGhee Tyson (TYS) is located 11.3 mi from the center of Knoxville. There are 0 flights from Chicago Midway to McGhee Tyson per day from 2 different airlines.

  • How long is the flight from Chicago Midway Airport to Knoxville?

    Airlines like Delta and Southwest fly from Chicago Midway Airport to Knoxville in about 6h 39m. The time it takes to get you to your destination can typically vary by up to 1h 41m. There are 460 mi between Chicago Midway Airport and Knoxville. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Chicago Midway Airport to Knoxville round-trip?

    Currently priced at $75, Allegiant Air will fly you from Chicago Midway Airport to Knoxville and back. In addition to Allegiant Air, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on Delta for as low as $138. Allegiant Air is priced at 62% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Midway to Knoxville that include hotel bookings?

    Yes. In addition to deals on Midway to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Midway to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Midway to Knoxville.

  • Can I find deals for business class flights from Midway to Knoxville?

    Yes. Cheapflights offers flight deals from Midway to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Oak Ridge
Murphy

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Midway to Knoxville

Discover the top 2 airlines that operate flights from Midway to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$75Average$118FlexibilityNo cancel feeOn-time88%
DeltaCheapest$138Average$303FlexibilityNo cancel feeOn-timeN/A

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