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$51+ Cheap flights from Midway (MDW) to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/31. Fares are subject to change and may not be available on all flights or dates of travel.
MDW — TYS
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Midway to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Midway (MDW) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$141
(Trip.com)

One-way from

$51
(Cheapflightsfares)

Popular in

April

Cheapest in

November

Average price

$114

Good round-trip deal

$91 or less

Good one-way deal

$58 or less
From Chicago Midway to Knoxville McGhee Tyson
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One-way flight from Chicago Midway to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 32% potential increase in price ($101 potential increase over avg. RT price).
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Cheapest flight prices on average. 9% potential price decrease ($19 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Chicago Midway to Knoxville McGhee Tyson.
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Price to beat on a one-way flight from Chicago Midway to Knoxville McGhee Tyson.
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Find flight deals from Midway to Knoxville

Cheapest flights from Midway to Knoxville
Explore the most affordable flight options available from Midway to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/127:50 pmMDW - TYS
Nonstop1h 31mAllegiant Air
Fri 9/196:24 pmTYS - MDW
Nonstop1h 36mAllegiant Air
Deal found 9/11$136
This Trip.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/197:50 pmMDW - TYS
Nonstop1h 31mAllegiant Air
Mon 9/226:24 pmTYS - MDW
Nonstop1h 36mAllegiant Air
Deal found 9/10$141
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/127:50 pmMDW - TYS
Nonstop1h 31mAllegiant Air
Mon 9/156:24 pmTYS - MDW
Nonstop1h 36mAllegiant Air
Deal found 9/10$146
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/293:16 pmMDW - TYS
Nonstop1h 31mAllegiant Air
Fri 10/310:44 amTYS - MDW
Nonstop1h 32mAllegiant Air
Deal found 9/9$156
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/104:12 pmMDW - TYS
Nonstop1h 25mMultiple Airlines
Thu 11/137:17 pmTYS - MDW
1 stop17h 13mMultiple Airlines
Deal found 9/9$165
This Cheapflightsfares deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1712:06 pmMDW - TYS
Nonstop1h 24mAllegiant Air
Mon 10/2010:46 amTYS - MDW
Nonstop1h 32mAllegiant Air
Deal found 9/9$172
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/293:16 pmMDW - TYS
Nonstop1h 31mAllegiant Air
Wed 10/112:15 pmTYS - MDW
1 stop28h 41mAllegiant Air
Deal found 9/10$173
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/32:45 pmMDW - TYS
Nonstop1h 24mMultiple Airlines
Mon 11/105:22 pmTYS - MDW
2 stops44h 19mMultiple Airlines
Deal found 9/10$176
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/267:50 pmMDW - TYS
Nonstop1h 31mAllegiant Air
Wed 10/112:15 pmTYS - MDW
1 stop28h 41mAllegiant Air
Deal found 9/10$177
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/278:24 pmMDW - TYS
Nonstop1h 24mMultiple Airlines
Thu 10/306:51 pmTYS - MDW
1 stop14h 41mMultiple Airlines
Deal found 9/10$178

Cheapflights Fare Finder

 
Customize your flight search to find flights from Midway to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Chicago Midway Airport to Knoxville that are best for you.

Fly from

Midway

Fly to

Knoxville

Route

Depart

Return

Price

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Fri 11/7

2:57 pm-5:22 pm

Nonstop1h 25m

Knoxville McGhee Tyson

Mon 11/10

5:22 pm-12:41 pm

2 stops44h 19m

$183

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Mon 10/27

8:24 pm-10:48 pm

Nonstop1h 24m

Knoxville McGhee Tyson

Thu 10/30

7:17 pm-11:30 am

1 stop17h 13m

$204

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Fri 9/26

7:50 pm-10:21 pm

Nonstop1h 31m

Knoxville McGhee Tyson

Mon 9/29

12:45 pm-11:20 pm

2 stops11h 35m

$206

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Mon 11/10

4:12 pm-6:37 pm

Nonstop1h 25m

Knoxville McGhee Tyson

Thu 11/13

9:00 am-10:03 pm

2 stops14h 03m

$208

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Fri 11/7

2:57 pm-5:22 pm

Nonstop1h 25m

Knoxville McGhee Tyson

Sun 11/9

1:16 pm-11:30 am

2 stops23h 14m

$208

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Tue 10/21

5:04 pm-11:07 pm

1 stop5h 03m

Knoxville McGhee Tyson

Sat 10/25

7:45 am-12:26 pm

1 stop5h 41m

$209

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Sat 9/27

4:25 pm-11:44 pm

1 stop6h 19m

Knoxville McGhee Tyson

Mon 9/29

6:08 pm-9:36 pm

1 stop4h 28m

$219

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Tue 9/23

6:00 am-10:56 am

1 stop3h 56m

Knoxville McGhee Tyson

Wed 10/1

5:45 am-9:40 am

1 stop4h 55m

$240

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Fri 10/24

2:45 pm-5:09 pm

Nonstop1h 24m

Knoxville McGhee Tyson

Sun 10/26

7:00 am-12:36 am

1 stop18h 36m

$242

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Fri 10/31

7:06 pm-9:30 pm

Nonstop1h 24m

$51

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/9

Showing 1-10 of 21 results
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Best time to book a flight from Midway to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Midway with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago Midway Airport to Knoxville

What is the cheapest time of day to fly from MDW to TYS?

Find hourly flight availability from Midway to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

A simple way to save on the total cost of your ticket is to fly from Chicago Midway Airport to Knoxville in the evening. If you’re flexible enough to do this you can expect to save up to 20% on your trip compared to booking a flight in the morning.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated September 11, 2025.
Read through reviews of airlines operating flights from Chicago Midway Airport to Knoxville, such as Delta and Allegiant Air. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Allegiant Air
7.2
Good
702 reviews
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Midway to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Chicago Midway?

    If you book a flight to Knoxville from Chicago Midway, you will be flying to McGhee Tyson, which is the city’s only airport. Knoxville McGhee Tyson (TYS) is located 11.3 mi from the center of Knoxville. There are 0 flights from Chicago Midway to McGhee Tyson per day from 2 different airlines.

  • What are the cheapest airlines flying from Chicago Midway Airport to Knoxville round-trip?

    Currently priced at $77, Allegiant Air will fly you from Chicago Midway Airport to Knoxville and back. In addition to Allegiant Air, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on Delta for as low as $193. Allegiant Air is priced at 63% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest flights from Chicago Midway Airport to Knoxville?

    While on average a flight from Chicago Midway Airport to Knoxville is generally $98, our data shows the cheapest flight currently is $50. When looking at the most popular route, (Chicago Midway - Knoxville McGhee Tyson), you can expect to pay $93 for that flight.

  • Can I find deals for flights from Midway to Knoxville that include hotel bookings?

    Yes. In addition to deals on Midway to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Midway to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Midway to Knoxville.

  • Can I find deals for business class flights from Midway to Knoxville?

    Yes. Cheapflights offers flight deals from Midway to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago Midway Airport to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Chicago Midway Airport to Knoxville (average of $294). Flying from Chicago Midway Airport to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Midway to Knoxville

Discover the top 2 airlines that operate flights from Midway to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$77Average$115FlexibilityNo cancel feeOn-time88%
DeltaCheapest$193Average$335FlexibilityNo cancel feeOn-timeN/A

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