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$125+ Cheap flights from Midway (MDW) to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/28. Fares are subject to change and may not be available on all flights or dates of travel.
MDW — TYS
Apr 15 — Apr 221
Wed 4/15
Wed 4/22
1 adult, Economy
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Cheap flight deals from Midway to Knoxville

Cheapest flights from Midway to Knoxville
Explore the most affordable flight options available from Midway to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 16, 2026.

This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/13:35 pm
MDW
-
TYS
1 stop4h 35m
Southwest
Tue 4/72:55 pm
TYS
-
MDW
1 stop6h 25m
Southwest
Deal found 3/10$229
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/179:16 am
MDW
-
TYS
1 stop9h 39m
Allegiant Air
Thu 5/211:22 pm
TYS
-
MDW
Nonstop1h 35m
Allegiant Air
Deal found 3/13$232
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/229:30 pm
MDW
-
TYS
1 stop23h 48m
Allegiant Air
Sun 5/241:22 pm
TYS
-
MDW
Nonstop1h 35m
Allegiant Air
Deal found 3/15$236
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/44:35 pm
MDW
-
TYS
1 stop3h 30m
Southwest
Tue 4/75:50 pm
TYS
-
MDW
1 stop5h 25m
Southwest
Deal found 3/11$239
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/812:04 pm
MDW
-
TYS
2 stops10h 35m
Multiple Airlines
Thu 6/111:22 pm
TYS
-
MDW
Nonstop1h 34m
Multiple Airlines
Deal found 3/11$248
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/311:15 am
MDW
-
TYS
2 stops9h 00m
Southwest
Tue 4/712:50 pm
TYS
-
MDW
2 stops8h 10m
Southwest
Deal found 3/10$249
This Southwest deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2810:15 am
MDW
-
TYS
2 stops9h 35m
Southwest
Tue 5/55:50 pm
TYS
-
MDW
1 stop5h 25m
Southwest
Deal found 3/13$254
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/269:23 pm
MDW
-
TYS
1 stop23h 11m
Allegiant Air
Sun 6/281:22 pm
TYS
-
MDW
Nonstop1h 34m
Allegiant Air
Deal found 3/10$257
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/112:46 pm
MDW
-
TYS
Nonstop1h 28m
Allegiant Air
Sat 6/139:00 am
TYS
-
MDW
1 stop24h 31m
Allegiant Air
Deal found 3/10$258

Find flight deals from Midway to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Midway (MDW) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 16, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$229
(Southwest)

One-way from

$125
(Southwest)

Popular in

April

Cheapest in

September

Average price

$189

Good round-trip deal

$106 or less
Provider with most accurate pricing for Chicago Midway-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Chicago Midway-Knoxville McGhee Tyson flights.
Search Deals
From Chicago Midway to Knoxville McGhee Tyson
Search Deals
One-way flight from Chicago Midway to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 20% potential increase in price ($51 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($17 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals
Price to beat on a round-trip flight from Chicago Midway to Knoxville McGhee Tyson.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Midway to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 16, 2026.
Use the filters below to find and compare flights from Chicago Midway Airport to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Wed 6/10

11:25 am-8:20 pm

2 stops7h 55m

Knoxville McGhee Tyson

Mon 6/15

4:20 pm-10:45 pm

1 stop7h 25m

$244

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Sat 4/11

2:15 pm-6:30 pm

1 stop3h 15m

Knoxville McGhee Tyson

Sat 4/18

6:40 am-1:10 pm

2 stops7h 30m

$254

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Tue 5/19

5:30 am-2:20 pm

1 stop7h 50m

Knoxville McGhee Tyson

Tue 5/19

5:50 pm-10:15 pm

1 stop5h 25m

$264

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Tue 4/28

12:45 pm-8:50 pm

2 stops7h 05m

Knoxville McGhee Tyson

Tue 5/5

7:05 am-3:25 pm

2 stops9h 20m

$274

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Sat 3/28

12:10 pm-10:10 pm

1 stop9h 00m

Knoxville McGhee Tyson

Tue 3/31

2:25 pm-9:20 pm

1 stop7h 55m

$304

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Sat 3/28

12:10 pm-10:10 pm

1 stop9h 00m

Knoxville McGhee Tyson

Thu 4/2

6:30 am-9:20 am

1 stop3h 50m

$329

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Fri 6/5

1:00 pm-10:20 pm

2 stops8h 20m

Knoxville McGhee Tyson

Sat 6/6

6:55 pm-7:10 am

2 stops13h 15m

$329

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Mon 6/8

5:10 pm-10:20 pm

1 stop4h 10m

Knoxville McGhee Tyson

Tue 6/9

8:10 am-2:00 pm

1 stop6h 50m

$333
Quickest round-trip

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Mon 4/6

6:07 pm-11:57 pm

1 stop4h 50m

Knoxville McGhee Tyson

Thu 4/9

5:40 am-9:56 am

1 stop5h 16m

$337
Cheapest one-way

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Tue 4/28

3:00 pm-7:40 pm

1 stop3h 40m

$125

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/14

Showing 1-10 of 18 resultsSorted by cheapest first
1
2

Compare providers for flights from Midway to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Midway to Knoxville in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Chicago Midway Airport-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Chicago Midway Airport-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Chicago Midway Airport-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Chicago Midway Airport-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago Midway Airport-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Midway to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Midway with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago Midway Airport to Knoxville

What is the cheapest time of day to fly from MDW to TYS?

Find hourly flight availability from Midway to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 16, 2026.

A simple way to save on the total cost of your ticket is to fly from Chicago Midway Airport to Knoxville in the evening. If you’re flexible enough to do this you can expect to save up to 32% on your trip compared to booking a flight in the morning.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated March 16, 2026.
Read through reviews of airlines operating flights from Chicago Midway Airport to Knoxville, such as Delta and Allegiant Air. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,296 reviews

Boarding

8.1

Comfort

7.9

Crew

8.5

Food

7.2

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,296 reviews
Delta
7.9
Good
8,296 reviews

Boarding

8.1

Comfort

7.9

Crew

8.5

Food

7.2

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Allegiant Air
7.3
Good
712 reviews
Delta
7.9
Good
8,296 reviews

Boarding

8.1

Comfort

7.9

Crew

8.5

Food

7.2

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Midway to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Chicago Midway?

    If you book a flight to Knoxville from Chicago Midway, you will be flying to McGhee Tyson, which is the city’s only airport. Knoxville McGhee Tyson (TYS) is located 11.3 mi from the center of Knoxville. There are 0 flights from Chicago Midway to McGhee Tyson per day from 2 different airlines.

  • How long is the flight from Chicago Midway Airport to Knoxville?

    Airlines like Southwest fly from Chicago Midway Airport to Knoxville in about 7h 55m. The time it takes to get you to your destination can typically vary by up to . There are 460 mi between Chicago Midway Airport and Knoxville.

  • What are the cheapest airlines flying from Chicago Midway Airport to Knoxville round-trip?

    Currently priced at $80, Allegiant Air will fly you from Chicago Midway Airport to Knoxville and back. In addition to Allegiant Air, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on Delta for as low as $138. Allegiant Air is priced at 59% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest flights from Chicago Midway Airport to Knoxville?

    While on average a flight from Chicago Midway Airport to Knoxville is generally $121, our data shows the cheapest flight currently is $55. When looking at the most popular route, (Chicago Midway - Knoxville McGhee Tyson), you can expect to pay $115 for that flight.

  • Can I find deals for flights from Midway to Knoxville that include hotel bookings?

    Yes. In addition to deals on Midway to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Midway to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Midway to Knoxville.

  • Can I find deals for business class flights from Midway to Knoxville?

    Yes. Cheapflights offers flight deals from Midway to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Murphy
Oak Ridge

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Midway to Knoxville

Discover the top 2 airlines that operate flights from Midway to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 16, 2026.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$80Average$121FlexibilityNo cancel feeOn-time88%
DeltaCheapest$138Average$273FlexibilityNo cancel feeOn-timeN/A

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