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$55+ Cheap flights from Chicago (CHI) to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/8. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — TYS
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Find cheap flights from Chicago to Knoxville with Cheapflights

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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

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Cheapflights Tip: The best prices from Chicago to Knoxville McGhee Tyson are usually found in September or January, booked 73 days in advance, depart on a Wednesday or Saturday and return on a Friday

Cheap flight deals from Chicago to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Chicago (CHI) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 30, 2025.

Most accurate provider

Justfly.com
3 stars

Most trusted provider

Justfly.com
3 stars

Round-trip from

$148
(Kiwi.com)

One-way from

$55
(Priceline)

Popular in

December

Cheapest in

September

Average price

$285

Good round-trip deal

$130 or less

Good one-way deal

$58 or less
Provider with most accurate pricing for Chicago (CHI)-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Chicago (CHI)-Knoxville McGhee Tyson flights.
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From Chicago (CHI) to Knoxville McGhee Tyson
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One-way flight from Chicago (CHI) to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 1% potential increase in price ($4 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Price to beat on a round-trip flight from Chicago (CHI) to Knoxville McGhee Tyson.
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Price to beat on a one-way flight from Chicago (CHI) to Knoxville McGhee Tyson.
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Find flight deals from Chicago to Knoxville

Cheapest flights from Chicago to Knoxville
Explore the most affordable flight options available from Chicago to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/108:00 amMDW - TYS
1 stop14h 14mMultiple Airlines
Fri 11/142:02 pmTYS - MDW
Nonstop1h 35mMultiple Airlines
Deal found 10/29$148
This Cheapflightsfares deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/317:06 pmMDW - TYS
Nonstop1h 24mAllegiant Air
Fri 11/71:32 pmTYS - MDW
Nonstop1h 35mAllegiant Air
Deal found 10/29$150
This Frontier deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/117:00 amORD - TYS
1 stop7h 57mFrontier
Sun 12/144:52 pmTYS - ORD
1 stop8h 20mFrontier
Deal found 10/28$163
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/212:11 pmMDW - TYS
Nonstop1h 25mAllegiant Air
Wed 11/266:18 pmTYS - MDW
Nonstop1h 36mAllegiant Air
Deal found 10/29$167
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/212:11 pmMDW - TYS
Nonstop1h 25mMultiple Airlines
Mon 11/246:30 amTYS - MDW
1 stop11h 22mMultiple Airlines
Deal found 10/29$170
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/242:11 pmMDW - TYS
Nonstop1h 25mAllegiant Air
Wed 11/266:18 pmTYS - MDW
Nonstop1h 36mAllegiant Air
Deal found 10/29$174
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/104:12 pmMDW - TYS
Nonstop1h 25mMultiple Airlines
Thu 11/136:58 pmTYS - MDW
1 stop28h 12mMultiple Airlines
Deal found 10/30$178
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/156:30 amMDW - TYS
1 stop28h 18mMultiple Airlines
Mon 11/2412:45 pmTYS - MDW
Nonstop1h 36mMultiple Airlines
Deal found 10/28$184
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/181:56 pmMDW - TYS
2 stops20h 58mMultiple Airlines
Fri 11/2112:45 pmTYS - MDW
Nonstop1h 36mMultiple Airlines
Deal found 10/29$185
This Mytrip deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/143:27 pmMDW - TYS
Nonstop1h 25mMultiple Airlines
Sun 11/167:07 pmTYS - MDW
1 stop17h 23mMultiple Airlines
Deal found 10/28$186
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/23:43 pmORD - TYS
1 stop19h 20mMultiple Airlines
Sun 12/75:23 pmTYS - ORD
1 stop24h 31mMultiple Airlines
Deal found 10/30$187
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/218:04 pmORD - TYS
Nonstop1h 51mUnited Airlines
Mon 11/246:45 amTYS - ORD
Nonstop2h 01mUnited Airlines
Deal found 10/30$189

Cheapflights Fare Finder

 
Customize your flight search to find flights from Chicago to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Chicago to Knoxville that are best for you.

Fly from

Chicago

Fly to

Knoxville

Route

Depart

Return

Price

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Sat 1/17

7:42 am-10:32 am

Nonstop1h 50m

Knoxville McGhee Tyson

Mon 1/19

6:45 am-7:48 am

Nonstop2h 03m

$189

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Mon 11/24

7:20 am-10:05 am

Nonstop1h 45m

Knoxville McGhee Tyson

Thu 11/27

8:26 am-9:30 am

Nonstop2h 04m

$189

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Mon 11/10

4:12 pm-6:37 pm

Nonstop1h 25m

Knoxville McGhee Tyson

Thu 11/13

7:00 am-12:37 pm

2 stops30h 37m

$201

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Sun 11/23

5:30 pm-10:30 am

1 stop16h 00m

Knoxville McGhee Tyson

Mon 11/24

12:45 pm-1:21 pm

Nonstop1h 36m

$203

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Thu 1/22

9:35 am-4:19 pm

1 stop5h 44m

Knoxville McGhee Tyson

Tue 1/27

6:19 am-11:47 am

1 stop6h 28m

$209

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Thu 12/4

1:20 pm-6:52 pm

1 stop4h 32m

Knoxville McGhee Tyson

Sat 12/6

12:49 pm-4:22 pm

1 stop4h 33m

$209

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Sat 11/22

1:26 pm-8:00 pm

1 stop5h 34m

Knoxville McGhee Tyson

Mon 11/24

5:35 am-9:52 am

1 stop5h 17m

$209

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Wed 11/19

10:47 am-4:51 pm

1 stop5h 04m

Knoxville McGhee Tyson

Thu 11/27

6:05 pm-11:40 pm

1 stop6h 35m

$209

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Sat 11/22

1:26 pm-8:00 pm

1 stop5h 34m

Knoxville McGhee Tyson

Thu 11/27

6:05 pm-11:40 pm

1 stop6h 35m

$209

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Wed 1/21

1:28 pm-8:47 pm

1 stop6h 19m

Knoxville McGhee Tyson

Sun 1/25

7:30 am-12:48 pm

1 stop6h 18m

$209

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Showing 1-10 of 44 results
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Compare providers for flights from Chicago to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Chicago to Knoxville in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
Justfly.comPrice Accuracy3 starsTrust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars
CheapTicketsDealPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Chicago-Knoxville flights, users find the pricing of Justfly.com to be most consistent on Cheapflights vs. Justfly.com Users can find the same prices on Chicago-Knoxville flight deals on Cheapflights vs. Justfly.com >95% of the time. Price accuracy is based on data collected from Chicago-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Chicago-Knoxville flights, Cheapflights users trust Justfly.com the most. Justfly.com has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Chicago to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Chicago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago to Knoxville

How far ahead should I book a flight from Chicago to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from Chicago to Knoxville. Price data was last updated on October 24, 2025.

Booking 73 days in advance of your planned departure date is, on average, the best time to get cheap flights from Chicago to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Chicago to Knoxville?

Currently, June is the cheapest month in which you can book a flight from Chicago to Knoxville (average of $62). Flying from Chicago to Knoxville in March is currently the most expensive (average of $190). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHI to TYS?

Find hourly flight availability from Chicago to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 44% on flights from Chicago to Knoxville by exploring options for tickets in the evening.

What is the cheapest day to fly from Chicago to Knoxville?

Use this chart to determine the cheapest time to fly round-trip from Chicago to Knoxville. Price data was last updated on October 26, 2025.

Travelers seeking maximum savings on their Chicago to Knoxville flight should consider departing on Thursday afternoons when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Chicago to Knoxville?

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated October 30, 2025.
Read through reviews of airlines operating flights from Chicago to Knoxville, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,998 reviews

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,998 reviews
Delta
7.9
Good
7,998 reviews

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,998 reviews
Delta
7.9
Good
7,998 reviews

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,035 reviews
Delta
7.9
Good
7,998 reviews

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Allegiant Air
7.2
Good
694 reviews
Delta
7.9
Good
7,998 reviews

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Chicago to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Chicago?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson is the airport most travelers will use when flying to Knoxville from Chicago. Booking flights from Chicago to McGhee Tyson (TYS) should be relatively easy as there are 11 daily inbound flights from Chicago from 4 different airlines.

  • How long is the flight from Chicago to Knoxville?

    United Airlines, Delta, and American Airlines can get you from Chicago to Knoxville in just under 1h 50m. Your travel time can differ by up to 3h 54m. Airlines will cover a distance of 475 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Chicago to Knoxville round-trip?

    Our cheapest airline available from Chicago to Knoxville is Allegiant Air. Our recent data shows that you can find tickets from as low as $80 on this airline. Additional options worth looking into are American Airlines and United Airlines, starting at $189 and $189 round-trip. Allegiant Air is priced at 70% lower than the current average price of a flight leaving 3 months from now.

  • What are the most reliable airlines from Chicago to Knoxville?

    No one likes to see their flight delayed. When booking a flight from Chicago to Knoxville consider choosing Republic Airways (98%), GoJet (91%) or Air New Zealand (79%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Chicago to Knoxville?

    While on average a flight from Chicago to Knoxville is generally $308, our data shows the cheapest flight currently is $168. When looking at the most popular route, (Chicago O'Hare Intl - Knoxville McGhee Tyson), you can expect to pay $189 for that flight.

  • Can I find deals for flights from Chicago to Knoxville that include hotel bookings?

    Yes. In addition to deals on Chicago to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Chicago to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Chicago to Knoxville.

  • Can I find deals for business class flights from Chicago to Knoxville?

    Yes. Cheapflights offers flight deals from Chicago to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago to Knoxville?

    Currently, June is the cheapest month in which you can book a flight from Chicago to Knoxville (average of $62). Flying from Chicago to Knoxville in March is currently the most expensive (average of $190). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Crossville
Corbin
Bryson City
Alcoa
Oak Ridge
Murphy

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Alternative routes for Chicago to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Chicago to Knoxville

Discover the top 4 airlines that operate flights from Chicago to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$80Average$116FlexibilityNo cancel feeOn-time88%
American AirlinesCheapest$189Average$301FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$189Average$329FlexibilityNo cancel feeOn-time69%
DeltaCheapest$193Average$318FlexibilityNo cancel feeOn-timeN/A

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