$49+ Cheap flights from Chicago (CHI) to Knoxville (TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/13. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — TYS
Dec 9 — Dec 161
Round-trip
1 adult, Economy
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Find cheap flights from Chicago to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Chicago to Knoxville McGhee Tyson are usually found in June or July, booked 73 days in advance, depart on a Thursday or Saturday and return on a Friday
Cheap flight deals from Chicago to Knoxville
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Cheapest flights from Chicago to KnoxvilleExplore the most affordable flight options available from Chicago to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 9, 2026.
Explore the most affordable flight options available from Chicago to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 9, 2026.
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/44:15 pm -
Nonstop1h 50m
Mon 12/76:00 am -
1 stop6h 34m
Deal found 11/4![American Airlines logo]()
$255
This CheapOair deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:09 pm -
Nonstop1h 30m
Mon 11/93:04 pm -
Nonstop1h 37m
Deal found 11/4![Allegiant Air logo]()
$258
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/133:16 pm -
Nonstop1h 30m
Wed 11/1812:56 pm -
1 stop29h 11m
Deal found 11/5![Allegiant Air logo]()
$259
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/108:35 pm -
Nonstop1h 51m
Mon 12/146:00 am -
1 stop6h 34m
Deal found 11/5![American Airlines logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/164:31 pm -
Nonstop1h 30m
Fri 11/209:32 pm -
2 stops17h 13m
Deal found 11/4![Multiple Airlines logo]()
$264
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/411:39 am -
1 stop5h 43m
Mon 12/72:36 pm -
1 stop7h 17m
Deal found 11/4![Delta logo]()
$265
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/133:16 pm -
Nonstop1h 30m
Wed 11/186:17 pm -
2 stops30h 30m
Deal found 11/5![Multiple Airlines logo]()
$265
This Cheapflightsfares deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/253:27 pm -
Nonstop1h 27m
Sun 11/291:58 pm -
Nonstop1h 39m
Deal found 11/4![Allegiant Air logo]()
$268
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/109:29 pm -
1 stop20h 13m
Mon 12/141:58 pm -
1 stop7h 26m
Deal found 11/5![Multiple Airlines logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:07 am -
1 stop30h 00m
Mon 12/141:58 pm -
1 stop7h 26m
Deal found 11/7![Multiple Airlines logo]()
$272
This CheapOair deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/202:30 pm -
Nonstop1h 27m
Mon 11/238:00 am -
Nonstop1h 39m
Deal found 11/5![Allegiant Air logo]()
$272
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/18:04 am -
1 stop6h 09m
Wed 12/96:17 pm -
1 stop6h 39m
Deal found 11/4![Delta logo]()
$273
Best flights from Chicago to KnoxvilleDiscover carefully curated flight deals from Chicago to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 9, 2026.
Discover carefully curated flight deals from Chicago to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 9, 2026.
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/156:00 am -
1 stop8h 10m
Mon 1/187:40 am -
2 stops6h 20m
Deal found 11/4![Southwest logo]()
$278
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/117:18 am -
Nonstop1h 56m
Sun 12/136:00 am -
Nonstop2h 06m
Deal found 11/4![United Airlines logo]()
$282
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/189:37 am -
1 stop6h 17m
Sun 12/206:00 am -
1 stop4h 13m
Deal found 11/5![Delta logo]()
$341
This Southwest deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/153:30 pm -
2 stops7h 00m
Sun 1/174:40 pm -
1 stop5h 40m
Deal found 11/6![Southwest logo]()
$302
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/97:18 am -
Nonstop1h 56m
Sun 12/206:00 am -
Nonstop2h 11m
Deal found 11/7![United Airlines logo]()
$329
This Southwest deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/510:20 am -
2 stops8h 25m
Sat 12/128:15 am -
2 stops10h 10m
Deal found 11/7![Southwest logo]()
$307
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/161:05 pm -
1 stop4h 22m
Mon 12/146:17 pm -
1 stop5h 37m
Deal found 11/4![Delta logo]()
$356
This Southwest deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/48:00 am -
1 stop3h 20m
Mon 12/75:15 pm -
1 stop6h 30m
Deal found 11/7![Southwest logo]()
$337
This Southwest deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/67:20 am -
1 stop6h 40m
Wed 12/95:15 pm -
1 stop6h 30m
Deal found 11/8![Southwest logo]()
$338
This Delta deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/286:25 am -
1 stop6h 14m
Mon 1/41:04 pm -
1 stop4h 23m
Deal found 11/8![Delta logo]()
$414
This Southwest deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/512:50 pm -
1 stop3h 50m
Sun 12/67:05 am -
2 stops9h 40m
Deal found 11/6![Southwest logo]()
$343
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/62:10 pm -
Nonstop1h 50m
Wed 12/96:00 am -
Nonstop2h 06m
Deal found 11/8![United Airlines logo]()
$457
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/25:00 am -
1 stop5h 56m
Sun 1/35:30 am -
1 stop5h 10m
Deal found 11/8![United Airlines logo]()
$471
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/169:55 am -
2 stops9h 55m
Mon 12/147:55 am -
2 stops12h 50m
Deal found 11/4![Southwest logo]()
$372
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/285:52 pm -
Nonstop1h 59m
Sun 1/35:30 am -
1 stop5h 10m
Deal found 11/8![United Airlines logo]()
$474
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/36:25 am -
1 stop6h 14m
Thu 1/75:15 am -
1 stop4h 25m
Deal found 11/5![Delta logo]()
$536
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/261:30 pm -
1 stop5h 06m
Sat 11/286:45 am -
Nonstop2h 08m
Deal found 11/8![United Airlines logo]()
$475
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/292:20 pm -
Nonstop1h 55m
Sun 1/36:00 am -
Nonstop2h 11m
Deal found 11/8![United Airlines logo]()
$483
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:55 am -
1 stop4h 35m
Tue 12/16:20 am -
2 stops10h 25m
Deal found 11/4![United Airlines logo]()
$524
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/510:55 am -
2 stops8h 42m
Sat 12/127:45 pm -
1 stop4h 44m
Deal found 11/7![United Airlines logo]()
$534
Last-minute flights from Chicago to KnoxvilleDiscover last-minute flight deals from Chicago to Knoxville. Data last updated November 9, 2026 and is based on user searches.
Discover last-minute flight deals from Chicago to Knoxville. Data last updated November 9, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:09 pm -
Nonstop1h 30m
Mon 11/93:04 pm -
Nonstop1h 37m
Deal found 11/4![Allegiant Air logo]()
$258
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/133:16 pm -
Nonstop1h 30m
Wed 11/1812:56 pm -
1 stop29h 11m
Deal found 11/5![Allegiant Air logo]()
$259
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/133:16 pm -
Nonstop1h 30m
Wed 11/186:17 pm -
2 stops30h 30m
Deal found 11/5![Multiple Airlines logo]()
$265
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/164:31 pm -
Nonstop1h 30m
Fri 11/209:32 pm -
2 stops17h 13m
Deal found 11/4![Multiple Airlines logo]()
$264
This CheapOair deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/202:30 pm -
Nonstop1h 27m
Mon 11/238:00 am -
Nonstop1h 39m
Deal found 11/5![Allegiant Air logo]()
$272
This Cheapflightsfares deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/253:27 pm -
Nonstop1h 27m
Sun 11/291:58 pm -
Nonstop1h 39m
Deal found 11/4![Allegiant Air logo]()
$268
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/18:04 am -
1 stop6h 09m
Wed 12/96:17 pm -
1 stop6h 39m
Deal found 11/4![Delta logo]()
$273
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/44:15 pm -
Nonstop1h 50m
Mon 12/76:00 am -
1 stop6h 34m
Deal found 11/4![American Airlines logo]()
$255
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/411:39 am -
1 stop5h 43m
Mon 12/72:36 pm -
1 stop7h 17m
Deal found 11/4![Delta logo]()
$265
This Kiwi.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:07 am -
1 stop30h 00m
Mon 12/141:58 pm -
1 stop7h 26m
Deal found 11/7![Multiple Airlines logo]()
$272
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/108:35 pm -
Nonstop1h 51m
Mon 12/146:00 am -
1 stop6h 34m
Deal found 11/5![American Airlines logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/109:29 pm -
1 stop20h 13m
Mon 12/141:58 pm -
1 stop7h 26m
Deal found 11/5![Multiple Airlines logo]()
$270
One-way flights from Chicago to KnoxvilleSearch for one-way flight options from Chicago to Knoxville. Find affordable one-way fares based on user searches. Data last updated November 9, 2026.
Search for one-way flight options from Chicago to Knoxville. Find affordable one-way fares based on user searches. Data last updated November 9, 2026.
This CheapOair deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/133:16 pm -
Nonstop1h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/8![Allegiant Air logo]()
$49
This Super.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/164:31 pm -
Nonstop1h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/7![Allegiant Air logo]()
$69
This CheapOair deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/239:29 am -
Nonstop1h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/8![Allegiant Air logo]()
$88
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/134:47 pm -
1 stop14h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/6![Multiple Airlines logo]()
$93
This Trip.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/66:07 am -
1 stop25h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Multiple Airlines logo]()
$109
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/74:15 pm -
Nonstop1h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![American Airlines logo]()
$127
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/181:54 pm -
1 stop6h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Delta logo]()
$137
This Southwest deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/112:45 pm -
1 stop6h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Southwest logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/66:10 pm -
1 stop23h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Allegiant Air logo]()
$142
This Southwest deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:05 am -
1 stop6h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/8![Southwest logo]()
$149
This Southwest deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/510:20 am -
2 stops8h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/7![Southwest logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/304:00 pm -
1 stop22h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Multiple Airlines logo]()
$155
Find flight deals from Chicago to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Chicago (CHI) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $255 (American Airlines) |
One-way from | $49 (CheapOair) |
Popular in | September |
Cheapest in | June |
Average price | $336 |
Good round-trip deal | $135 or less |
Good one-way deal | $223 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Chicago to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 9, 2026.
Use the filters below to find and compare flights from Chicago to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoKnoxville
ORD Chicago O'Hare Intl - TYS Knoxville McGhee Tyson
ORDTYS
Chicago O'Hare Intl
Fri 11/27
5:59 pm-8:54 pm
Nonstop1h 55m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$127
ChicagoKnoxville
ORD Chicago O'Hare Intl - TYS Knoxville McGhee Tyson
ORDTYS
Chicago O'Hare Intl
Mon 1/18
9:56 am-6:18 pm
1 stop7h 22m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$137
ChicagoKnoxville
MDW Chicago Midway - TYS Knoxville McGhee Tyson
MDWTYS
Chicago Midway
Mon 1/18
1:41 pm-9:31 pm
1 stop6h 50m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$137
ChicagoKnoxville
MDW Chicago Midway - TYS Knoxville McGhee Tyson
MDWTYS
Chicago Midway
Tue 12/1
7:05 am-2:05 pm
1 stop6h 00m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$149
ChicagoKnoxville
MDW Chicago Midway - TYS Knoxville McGhee Tyson
MDWTYS
Chicago Midway
Tue 12/15
12:45 pm-7:50 pm
1 stop6h 05m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$149
ChicagoKnoxville
MDW Chicago Midway - TYS Knoxville McGhee Tyson
MDWTYS
Chicago Midway
Mon 12/7
12:45 pm-7:50 pm
1 stop6h 05m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$164
Quickest round-trip
ChicagoKnoxville
MDW Chicago Midway - TYS Knoxville McGhee Tyson
MDWTYS
Chicago Midway
Fri 11/20
2:30 pm-4:57 pm
Nonstop1h 27m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$169
ChicagoKnoxville
MDW Chicago Midway - TYS Knoxville McGhee Tyson
MDWTYS
Chicago Midway
Fri 1/1
12:45 pm-7:50 pm
1 stop6h 05m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$174
ChicagoKnoxville
ORD Chicago O'Hare Intl - TYS Knoxville McGhee Tyson
ORDTYS
Chicago O'Hare Intl
Tue 11/24
8:55 pm-11:47 pm
Nonstop1h 52m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$180
ChicagoKnoxville
ORD Chicago O'Hare Intl - TYS Knoxville McGhee Tyson
ORDTYS
Chicago O'Hare Intl
Tue 12/1
8:15 am-4:19 pm
2 stops31h 04m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$191
Showing 1-10 of 40 resultsSorted by cheapest first
Compare providers for flights from Chicago to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Chicago to Knoxville in November.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Chicago-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Chicago-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Chicago-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Chicago-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Chicago to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Chicago with our price prediction graph.
CHI-TYS
MDW-TYS
ORD-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago to Knoxville
CHI-TYS
MDW-TYS
ORD-TYS
What is the cheapest month to book a flight from Chicago to Knoxville?
Currently, June is the cheapest month in which you can book a flight from Chicago to Knoxville (average of $256). Flying from Chicago to Knoxville in September is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from CHI to TYS?
Find hourly flight availability from Chicago to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 9, 2026.
Unlike in the afternoon, when flights are generally more expensive, you can save up to 23% on flights from Chicago to Knoxville by exploring options for tickets at noon.
Weekly flight availability from Chicago to Knoxville
Explore weekly flight availability from Chicago to Knoxville. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated November 9, 2026.
The most flights from CHI to TYS are scheduled on a Sunday (28 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (18 on average).
How much does it cost to fly round-trip from Chicago to Knoxville?
Airfare is below average for this route at the moment.
Chicago to Knoxville flights typically cost between $259 and $456 in December.The cheapest round-trip price found within the last 5 days was $255 on American Airlines (Dec 4-Dec 7).
How far ahead should I book a flight from Chicago to Knoxville?
Booking 74 days in advance of your planned departure date is, on average, the best time to get cheap flights from Chicago to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest day to fly from Chicago to Knoxville?
Use this chart to determine the cheapest time to fly round-trip from Chicago to Knoxville. Price data was last updated on November 7, 2026.
Travelers seeking maximum savings on their Chicago to Knoxville flight should consider departing on Tuesday at noon when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated November 9, 2026.
Read through reviews of airlines operating flights from Chicago to Knoxville, such as Southwest,United Airlines, andAllegiant Air. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
8.0
Entertainment
7.5
Food
7.0
Reviews
1 / 20
8.0
ExcellentJohn,May 2025
PVD - BNA
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
8.0
Entertainment
7.5
Food
7.0
Reviews
1 / 20
8.0
ExcellentJohn,May 2025
PVD - BNA
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
8.0
Entertainment
7.5
Food
7.0
Reviews
1 / 20
8.0
ExcellentJohn,May 2025
PVD - BNA
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
8.0
Entertainment
7.5
Food
7.0
Reviews
1 / 20
8.0
ExcellentJohn,May 2025
PVD - BNA
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
8.0
Entertainment
7.5
Food
7.0
Reviews
1 / 20
8.0
ExcellentJohn,May 2025
PVD - BNA
Related info for your journey
Find useful and relevant information for your journey from Chicago to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Newport
Bryson City
Crossville
Morristown
Murphy
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Other flights to Knoxville
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Top 4 airlines flying from Chicago to Knoxville
Discover the top 4 airlines that operate flights from Chicago to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$84 | Average$151 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$161 | Average$413 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$188 | Average$363 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$189 | Average$368 | FlexibilityNo cancel fee | On-time69% |