How long is the flight from Chicago to Knoxville?

Allegiant Air, United Airlines, and Delta can get you from Chicago to Knoxville in just under 1h 31m. Your travel time can differ by up to 2h 28m. Airlines will cover a distance of 460 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

What are the cheapest airlines flying from Chicago to Knoxville round-trip?

Our cheapest airline available from Chicago to Knoxville is Allegiant Air. Our recent data shows that you can find tickets from as low as $77 on this airline. Additional options worth looking into are American Airlines and United Airlines, starting at $180 and $190 round-trip. Allegiant Air is priced at 71% lower than the current average price of a flight leaving 3 months from now.

What are the cheapest airlines to fly from Chicago to Knoxville one-way?

To fly one-way, consider booking your trip with Allegiant Air, which is currently one of the cheapest options available, starting at $77. Frontier flights start at $98 while deals on United Airlines start at $129 one-way.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

What are the cheapest flights from Chicago to Knoxville?

While on average a flight from Chicago to Knoxville is generally $301, our data shows the cheapest flight currently is $128. When looking at the most popular route, (Chicago O'Hare Intl - Knoxville McGhee Tyson), you can expect to pay $189 for that flight.

What are the most reliable airlines from Chicago to Knoxville?

No one likes to see their flight delayed. When booking a flight from Chicago to Knoxville consider choosing GoJet (90%), Republic Airways (85%) or Envoy Air (82%) as they are the most reliable in getting you off to your destination on time.

What airport do you fly into for flights to Knoxville from Chicago?

Located just 11.3 mi from the city center, Knoxville McGhee Tyson is the airport most travelers will use when flying to Knoxville from Chicago. Booking flights from Chicago to McGhee Tyson (TYS) should be relatively easy as there are 23 daily inbound flights from Chicago from 4 different airlines.

Can I find deals for flights from Chicago to Knoxville that include hotel bookings?

Yes. In addition to deals on Chicago to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Chicago to Knoxville?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Chicago to Knoxville.

Can I find deals for business class flights from Chicago to Knoxville?

Yes. Cheapflights offers flight deals from Chicago to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$77+ Flights from Chicago to Knoxville

Q: How much does it cost to fly round-trip from Chicago to Knoxville?

Airfare is below average for this route at the moment. Chicago to Knoxville flights typically cost between $151 and $349 in October. The cheapest round-trip price found within the last 3 days was $127 on Allegiant Air (Oct 24-Oct 27).

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1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Chicago to Knoxville McGhee Tyson are usually found in January or September, booked 73 days in advance, depart on a Wednesday or Saturday and return on a Friday

Cheap flight deals from Chicago to Knoxville

Round-trip from	$127 (Cheapflightsfares)
One-way from	$77 (Cheapflightsfares)
Popular in	December
Cheapest in	January
Average price	$244
Good round-trip deal	$91 or less
Good one-way deal	$52 or less

From Chicago (CHI) to Knoxville McGhee Tyson

Search Deals

One-way flight from Chicago (CHI) to Knoxville McGhee Tyson

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Highest demand for flights based on searches. 1% potential increase in price ($5 potential increase over avg. RT price).

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Cheapest flight prices on average. 2% potential price decrease ($6 potential savings vs. average RT price).

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Average for round-trip flights in September 2025

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Price to beat on a round-trip flight from Chicago (CHI) to Knoxville McGhee Tyson.

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Price to beat on a one-way flight from Chicago (CHI) to Knoxville McGhee Tyson.

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Find flight deals from Chicago to Knoxville

Cheapest flights from Chicago to Knoxville
Explore the most affordable flight options available from Chicago to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

Mon 9/227:50 pmMDW - TYS

Nonstop1h 31mAllegiant Air

Mon 9/291:50 pmTYS - MDW

Nonstop1h 36mAllegiant Air

Deal found 9/15

$127

Fri 11/72:57 pmMDW - TYS

Nonstop1h 25mAllegiant Air

Fri 11/142:02 pmTYS - MDW

Nonstop1h 35mAllegiant Air

Deal found 9/15

$128

Mon 11/104:12 pmMDW - TYS

Nonstop1h 25mAllegiant Air

Fri 11/142:02 pmTYS - MDW

Nonstop1h 35mAllegiant Air

Deal found 9/15

$129

Mon 9/293:16 pmMDW - TYS

Nonstop1h 31mAllegiant Air

Fri 10/310:44 amTYS - MDW

Nonstop1h 32mAllegiant Air

Deal found 9/15

$138

Fri 9/197:50 pmMDW - TYS

Nonstop1h 31mAllegiant Air

Mon 9/291:50 pmTYS - MDW

Nonstop1h 36mAllegiant Air

Deal found 9/15

$141

Fri 10/242:45 pmMDW - TYS

Nonstop1h 24mAllegiant Air

Fri 10/315:44 pmTYS - MDW

Nonstop1h 32mAllegiant Air

Deal found 9/15

$144

Mon 9/227:50 pmMDW - TYS

Nonstop1h 31mAllegiant Air

Fri 9/266:24 pmTYS - MDW

Nonstop1h 36mAllegiant Air

Deal found 9/17

$152

Fri 10/242:45 pmMDW - TYS

Nonstop1h 24mAllegiant Air

Mon 10/277:02 pmTYS - MDW

Nonstop1h 32mAllegiant Air

Deal found 9/15

$153

Fri 9/267:50 pmMDW - TYS

Nonstop1h 31mAllegiant Air

Wed 10/112:15 pmTYS - MDW

1 stop28h 41mAllegiant Air

Deal found 9/15

$178

Fri 11/72:57 pmMDW - TYS

Nonstop1h 25mMultiple Airlines

Mon 11/172:22 pmTYS - MDW

1 stop7h 09mMultiple Airlines

Deal found 9/15

$181

Fri 11/72:57 pmMDW - TYS

Nonstop1h 25mMultiple Airlines

Thu 11/137:17 pmTYS - MDW

1 stop17h 13mMultiple Airlines

Deal found 9/15

$184

Fri 11/143:27 pmMDW - TYS

Nonstop1h 25mAllegiant Air

Mon 11/172:47 pmTYS - MDW

Nonstop1h 35mAllegiant Air

Deal found 9/16

$186

Best flights from Chicago to Knoxville
Discover carefully curated flight deals from Chicago to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2025.

Mon 9/227:50 pmMDW - TYS

Nonstop1h 31mAllegiant Air

Fri 9/266:24 pmTYS - MDW

Nonstop1h 36mAllegiant Air

Deal found 9/17

$152

Tue 10/148:00 pmORD - TYS

Nonstop1h 50mUnited Airlines

Tue 10/212:00 pmTYS - ORD

Nonstop2h 02mUnited Airlines

Deal found 9/14

$189

Wed 11/59:52 amORD - TYS

1 stop3h 59mDelta

Sat 11/82:41 pmTYS - ORD

1 stop5h 08mDelta

Deal found 9/16

$209

Fri 9/267:50 pmMDW - TYS

Nonstop1h 31mMultiple Airlines

Mon 9/2912:45 pmTYS - MDW

2 stops11h 35mMultiple Airlines

Deal found 9/16

$211

Fri 11/146:37 pmORD - TYS

Nonstop1h 47mAmerican Airlines

Mon 11/176:16 pmTYS - ORD

Nonstop2h 04mAmerican Airlines

Deal found 9/16

$243

Thu 10/28:00 pmORD - TYS

Nonstop1h 50mUnited Airlines

Tue 10/77:00 amTYS - ORD

Nonstop1h 55mUnited Airlines

Deal found 9/15

$194

Wed 10/17:15 amORD - TYS

Nonstop1h 55mUnited Airlines

Wed 10/810:51 amTYS - ORD

Nonstop2h 04mUnited Airlines

Deal found 9/17

$194

Thu 10/29:25 amORD - TYS

1 stop6h 30mDelta

Mon 10/68:10 pmTYS - ORD

1 stop4h 48mDelta

Deal found 9/15

$214

Fri 10/312:06 pmMDW - TYS

Nonstop1h 24mMultiple Airlines

Mon 10/68:10 pmTYS - MDW

2 stops28h 15mMultiple Airlines

Deal found 9/16

$243

Thu 2/1910:40 amORD - TYS

1 stop4h 00mAmerican Airlines

Sun 2/226:50 pmTYS - ORD

Nonstop2h 00mAmerican Airlines

Deal found 9/17

$244

Tue 11/186:45 amORD - TYS

1 stop7h 01mDelta

Sat 11/223:51 pmTYS - ORD

1 stop3h 56mDelta

Deal found 9/15

$234

Tue 10/78:05 amMDW - TYS

2 stops34h 18mMultiple Airlines

Fri 10/1710:44 amTYS - MDW

Nonstop1h 32mMultiple Airlines

Deal found 9/16

$251

Sat 11/86:00 amMDW - TYS

1 stop3h 28mDelta

Fri 11/148:05 pmTYS - MDW

1 stop4h 27mDelta

Deal found 9/15

$234

Thu 3/1210:35 amORD - TYS

Nonstop1h 43mUnited Airlines

Sun 3/152:00 pmTYS - ORD

Nonstop1h 55mUnited Airlines

Deal found 9/16

$237

Sun 9/218:06 amMDW - TYS

2 stops9h 39mMultiple Airlines

Mon 9/226:24 pmTYS - MDW

Nonstop1h 36mMultiple Airlines

Deal found 9/16

$261

Sat 9/276:00 pmORD - TYS

1 stop4h 44mDelta

Mon 9/296:08 pmTYS - ORD

1 stop4h 17mDelta

Deal found 9/16

$244

Sat 9/271:43 pmMDW - TYS

1 stop7h 52mDelta

Mon 9/296:08 pmTYS - MDW

1 stop4h 28mDelta

Deal found 9/16

$244

Thu 9/256:00 amMDW - TYS

1 stop3h 42mDelta

Wed 10/15:45 amTYS - MDW

1 stop4h 55mDelta

Deal found 9/15

$244

Thu 9/256:00 amMDW - TYS

1 stop3h 42mDelta

Tue 9/306:08 pmTYS - MDW

1 stop4h 28mDelta

Deal found 9/15

$244

Sat 9/271:43 pmMDW - TYS

1 stop7h 52mDelta

Wed 10/15:45 amTYS - MDW

1 stop4h 55mDelta

Deal found 9/15

$244

Wed 10/112:55 pmORD - TYS

1 stop6h 44mDelta

Wed 10/85:19 pmTYS - ORD

1 stop6h 07mDelta

Deal found 9/17

$248

Wed 9/246:00 amMDW - TYS

1 stop3h 56mDelta

Sun 9/285:45 amTYS - MDW

1 stop4h 55mDelta

Deal found 9/17

$271

Last-minute flights from Chicago to Knoxville
Discover last-minute flight deals from Chicago to Knoxville. Data last updated September 17, 2025 and is based on user searches.

Fri 9/197:50 pmMDW - TYS

Nonstop1h 31mAllegiant Air

Mon 9/291:50 pmTYS - MDW

Nonstop1h 36mAllegiant Air

Deal found 9/15

$141

Mon 9/227:50 pmMDW - TYS

Nonstop1h 31mAllegiant Air

Mon 9/291:50 pmTYS - MDW

Nonstop1h 36mAllegiant Air

Deal found 9/15

$127

Mon 9/227:50 pmMDW - TYS

Nonstop1h 31mAllegiant Air

Fri 9/266:24 pmTYS - MDW

Nonstop1h 36mAllegiant Air

Deal found 9/17

$152

Fri 9/267:50 pmMDW - TYS

Nonstop1h 31mAllegiant Air

Wed 10/112:15 pmTYS - MDW

1 stop28h 41mAllegiant Air

Deal found 9/15

$178

Fri 9/267:50 pmMDW - TYS

Nonstop1h 31mMultiple Airlines

Sat 9/279:31 pmTYS - MDW

1 stop12h 47mMultiple Airlines

Deal found 9/15

$188

Fri 9/267:50 pmMDW - TYS

Nonstop1h 31mMultiple Airlines

Mon 9/2912:45 pmTYS - MDW

2 stops11h 35mMultiple Airlines

Deal found 9/14

$198

Mon 9/293:16 pmMDW - TYS

Nonstop1h 31mAllegiant Air

Fri 10/310:44 amTYS - MDW

Nonstop1h 32mAllegiant Air

Deal found 9/15

$138

Wed 10/17:15 amORD - TYS

Nonstop1h 55mUnited Airlines

Wed 10/810:51 amTYS - ORD

Nonstop2h 04mUnited Airlines

Deal found 9/17

$194

Thu 10/28:00 pmORD - TYS

Nonstop1h 50mUnited Airlines

Mon 10/68:50 amTYS - ORD

Nonstop2h 02mUnited Airlines

Deal found 9/16

$199

Tue 10/148:00 pmORD - TYS

Nonstop1h 50mUnited Airlines

Tue 10/212:00 pmTYS - ORD

Nonstop2h 02mUnited Airlines

Deal found 9/14

$189

Fri 10/242:45 pmMDW - TYS

Nonstop1h 24mAllegiant Air

Fri 10/315:44 pmTYS - MDW

Nonstop1h 32mAllegiant Air

Deal found 9/15

$144

Fri 10/242:45 pmMDW - TYS

Nonstop1h 24mAllegiant Air

Mon 10/277:02 pmTYS - MDW

Nonstop1h 32mAllegiant Air

Deal found 9/15

$153

One-way flights from Chicago to Knoxville
Search for one-way flight options from Chicago to Knoxville. Find affordable one-way fares based on user searches. Data last updated September 17, 2025.

Mon 10/612:08 pmMDW - TYS

Nonstop1h 24mAllegiant Air

Deal found 9/16

$77

Thu 11/136:00 amORD - TYS

1 stop11h 22mFrontier

Deal found 9/15

$98

Thu 12/115:15 pmORD - TYS

1 stop24h 59mMultiple Airlines

Deal found 9/15

$100

Thu 11/66:00 amORD - TYS

1 stop6h 44mMultiple Airlines

Deal found 9/16

$110

Mon 11/175:59 pmORD - TYS

1 stop15h 35mMultiple Airlines

Deal found 9/16

$115

Sun 12/145:15 pmORD - TYS

1 stop24h 59mMultiple Airlines

Deal found 9/16

$125

Tue 10/148:00 pmORD - TYS

Nonstop1h 50mUnited Airlines

Deal found 9/15

$129

Fri 10/174:53 pmORD - TYS

1 stop16h 25mMultiple Airlines

Deal found 9/16

$133

Sun 12/1411:41 amORD - TYS

2 stops27h 11mFrontier

Deal found 9/15

$134

Sun 9/286:20 amMDW - TYS

2 stops11h 25mMultiple Airlines

Deal found 9/16

$134

Wed 11/127:20 amORD - TYS

1 stop29h 24mMultiple Airlines

Deal found 9/15

$135

Thu 10/235:20 pmMDW - TYS

2 stops27h 53mMultiple Airlines

Deal found 9/15

$151

Fly from

Fly to

Route

Depart

Return

Price

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Mon 9/22

7:50 pm-10:21 pm

Nonstop1h 31m

Knoxville McGhee Tyson

Fri 9/26

6:24 pm-7:00 pm

Nonstop1h 36m

$152

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Tue 10/14

8:00 pm-10:50 pm

Nonstop1h 50m

Knoxville McGhee Tyson

Tue 10/21

2:00 pm-3:02 pm

Nonstop2h 02m

$189

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Thu 10/2

8:00 pm-10:50 pm

Nonstop1h 50m

Knoxville McGhee Tyson

Tue 10/7

7:00 am-7:55 am

Nonstop1h 55m

$194

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Wed 10/1

7:15 am-10:10 am

Nonstop1h 55m

Knoxville McGhee Tyson

Wed 10/8

10:51 am-11:55 am

Nonstop2h 04m

$194

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Wed 11/5

9:52 am-2:51 pm

1 stop3h 59m

Knoxville McGhee Tyson

Sat 11/8

2:41 pm-6:49 pm

1 stop5h 08m

$209

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Fri 9/26

7:50 pm-10:21 pm

Nonstop1h 31m

Knoxville McGhee Tyson

Mon 9/29

12:45 pm-11:20 pm

2 stops11h 35m

$211

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Thu 10/2

9:25 am-4:55 pm

1 stop6h 30m

Knoxville McGhee Tyson

Mon 10/6

8:10 pm-11:58 pm

1 stop4h 48m

$214

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Tue 11/18

6:45 am-2:46 pm

1 stop7h 01m

Knoxville McGhee Tyson

Sat 11/22

3:51 pm-6:47 pm

1 stop3h 56m

$234

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Sat 11/8

6:00 am-10:28 am

1 stop3h 28m

Knoxville McGhee Tyson

Fri 11/14

8:05 pm-11:32 pm

1 stop4h 27m

$234

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Thu 3/12

10:35 am-1:18 pm

Nonstop1h 43m

Knoxville McGhee Tyson

Sun 3/15

2:00 pm-2:55 pm

Nonstop1h 55m

$237

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Showing 1-10 of 44 results

...

Best time to book a flight from Chicago to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Chicago with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago to Knoxville

How far ahead should I book a flight from Chicago to Knoxville?

Booking 73 days in advance of your planned departure date is, on average, the best time to get cheap flights from Chicago to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Chicago to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Chicago to Knoxville (average of $295). Flying from Chicago to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHI to TYS?

Unlike in the morning, when flights are generally more expensive, you can save up to 9% on flights from Chicago to Knoxville by exploring options for tickets at noon.

What is the cheapest day to fly from Chicago to Knoxville?

Travelers seeking maximum savings on their Chicago to Knoxville flight should consider departing on Friday at noon when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Chicago to Knoxville

The most flights from CHI to TYS are scheduled on a Monday (29 on average). You will have fewer flight options on Friday, which is when the least amount of flights are scheduled (20 on average).

How much does it cost to fly round-trip from Chicago to Knoxville?

Reviews of airlines servicing Knoxville

Read through reviews of airlines operating flights from Chicago to Knoxville, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,961 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,961 reviews

Delta

8.0

Very good

7,961 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

United Airlines

7.4

Good

8,926 reviews

Delta

8.0

Very good

7,961 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,961 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Allegiant Air

7.2

Good

699 reviews

Delta

8.0

Very good

7,961 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

What airport do you fly into for flights to Knoxville from Chicago?
Located just 11.3 mi from the city center, Knoxville McGhee Tyson is the airport most travelers will use when flying to Knoxville from Chicago. Booking flights from Chicago to McGhee Tyson (TYS) should be relatively easy as there are 23 daily inbound flights from Chicago from 4 different airlines.
How long is the flight from Chicago to Knoxville?
Allegiant Air, United Airlines, and Delta can get you from Chicago to Knoxville in just under 1h 31m. Your travel time can differ by up to 2h 28m. Airlines will cover a distance of 460 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.
What are the cheapest airlines flying from Chicago to Knoxville round-trip?
Our cheapest airline available from Chicago to Knoxville is Allegiant Air. Our recent data shows that you can find tickets from as low as $77 on this airline. Additional options worth looking into are American Airlines and United Airlines, starting at $180 and $190 round-trip. Allegiant Air is priced at 71% lower than the current average price of a flight leaving 3 months from now.
What are the cheapest airlines to fly from Chicago to Knoxville one-way?
To fly one-way, consider booking your trip with Allegiant Air, which is currently one of the cheapest options available, starting at $77. Frontier flights start at $98 while deals on United Airlines start at $129 one-way.
What are the most reliable airlines from Chicago to Knoxville?
No one likes to see their flight delayed. When booking a flight from Chicago to Knoxville consider choosing GoJet (90%), Republic Airways (85%) or Envoy Air (82%) as they are the most reliable in getting you off to your destination on time.
What are the cheapest flights from Chicago to Knoxville?
While on average a flight from Chicago to Knoxville is generally $301, our data shows the cheapest flight currently is $128. When looking at the most popular route, (Chicago O'Hare Intl - Knoxville McGhee Tyson), you can expect to pay $189 for that flight.
Can I find deals for flights from Chicago to Knoxville that include hotel bookings?
Yes. In addition to deals on Chicago to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Chicago to Knoxville?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Chicago to Knoxville.
Can I find deals for business class flights from Chicago to Knoxville?
Yes. Cheapflights offers flight deals from Chicago to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Chicago to Knoxville?
Currently, January is the cheapest month in which you can book a flight from Chicago to Knoxville (average of $295). Flying from Chicago to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Morristown

Cherokee

Corbin

Alcoa

Oak Ridge

Murphy

Browse thousands of different options on Cheapflights for your next trip

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Complete your trip

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Other flights to Knoxville

Top 4 airlines flying from Chicago to Knoxville

Airline	Cheapest	Average	Flexibility	On-time
Allegiant Air	Cheapest$77	Average$115	FlexibilityNo cancel fee	On-time88%
American Airlines	Cheapest$180	Average$300	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$190	Average$335	FlexibilityNo cancel fee	On-time69%
Delta	Cheapest$193	Average$335	FlexibilityNo cancel fee	On-timeN/A

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$77+ Cheap flights from Chicago (CHI) to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/6. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Chicago to Knoxville with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Chicago to Knoxville McGhee Tyson are usually found in January or September, booked 73 days in advance, depart on a Wednesday or Saturday and return on a Friday

Cheap flight deals from Chicago to Knoxville

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Cheapest flights from Chicago to KnoxvilleExplore the most affordable flight options available from Chicago to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

Explore the most affordable flight options available from Chicago to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

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Use this chart to determine the optimal time to book a round-trip flight from Chicago to Knoxville. Price data was last updated on September 12, 2025.

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Find hourly flight availability from Chicago to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

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Use this chart to determine the cheapest time to fly round-trip from Chicago to Knoxville. Price data was last updated on September 14, 2025.

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Reviews of airlines servicing Knoxville

Read through reviews of airlines operating flights from Chicago to Knoxville, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

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Cheapest flights from Chicago to Knoxville
Explore the most affordable flight options available from Chicago to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.