$56+ Cheap flights from Chicago (CHI) to Knoxville (TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/9. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — TYS
Nov 29 — Dec 61
Round-trip
1 adult, Economy
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Find cheap flights from Chicago to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Chicago to Knoxville McGhee Tyson are usually found in June or July, booked 73 days in advance, depart on a Thursday or Saturday and return on a Friday
Cheap flight deals from Chicago to Knoxville
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Cheapest flights from Chicago to KnoxvilleExplore the most affordable flight options available from Chicago to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
Explore the most affordable flight options available from Chicago to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/18:00 am -
1 stop3h 20m
Fri 12/42:40 pm -
2 stops9h 05m
Deal found 10/29![Southwest logo]()
$258
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/109:34 pm -
1 stop20h 08m
Mon 12/148:00 am -
2 stops14h 42m
Deal found 10/29![Multiple Airlines logo]()
$259
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:30 am -
1 stop4h 57m
Fri 12/411:49 am -
1 stop5h 28m
Deal found 10/29![Delta logo]()
$261
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/48:20 am -
2 stops25h 17m
Mon 12/71:58 pm -
1 stop7h 31m
Deal found 10/27![Multiple Airlines logo]()
$262
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/219:00 pm -
Nonstop1h 50m
Wed 11/258:50 pm -
Nonstop2h 09m
Deal found 10/28![American Airlines logo]()
$265
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/274:00 pm -
1 stop3h 35m
Mon 12/75:15 pm -
1 stop6h 30m
Deal found 10/28![Southwest logo]()
$265
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/133:16 pm -
Nonstop1h 30m
Mon 11/168:44 pm -
2 stops28h 03m
Deal found 10/28![Multiple Airlines logo]()
$266
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/94:31 pm -
Nonstop1h 30m
Wed 11/1110:55 am -
2 stops13h 52m
Deal found 10/27![Multiple Airlines logo]()
$268
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/218:59 pm -
Nonstop1h 51m
Fri 1/812:02 pm -
Nonstop2h 10m
Deal found 10/28![American Airlines logo]()
$269
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/254:08 pm -
Nonstop1h 44m
Mon 11/308:50 pm -
Nonstop2h 09m
Deal found 10/28![American Airlines logo]()
$270
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/18:00 am -
1 stop3h 20m
Tue 12/81:00 pm -
2 stops7h 05m
Deal found 10/25![Southwest logo]()
$270
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/278:05 am -
1 stop4h 21m
Fri 12/47:44 am -
Nonstop2h 26m
Deal found 10/28![American Airlines logo]()
$271
Best flights from Chicago to KnoxvilleDiscover carefully curated flight deals from Chicago to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
Discover carefully curated flight deals from Chicago to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/11:15 pm -
2 stops6h 35m
Fri 12/42:40 pm -
2 stops9h 05m
Deal found 10/29![Southwest logo]()
$263
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/291:41 pm -
1 stop6h 50m
Mon 2/17:08 am -
1 stop6h 53m
Deal found 10/27![Delta logo]()
$265
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:59 pm -
Nonstop1h 55m
Fri 11/205:40 pm -
Nonstop2h 03m
Deal found 10/26![United Airlines logo]()
$305
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/259:07 am -
1 stop10h 41m
Tue 2/93:52 pm -
1 stop23h 10m
Deal found 10/27![Allegiant Air logo]()
$322
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:04 pm -
1 stop17h 00m
Tue 12/13:42 pm -
2 stops45h 15m
Deal found 10/26![Multiple Airlines logo]()
$507
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/2910:00 am -
2 stops8h 40m
Mon 2/16:45 am -
2 stops8h 35m
Deal found 10/27![Southwest logo]()
$275
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/61:41 pm -
1 stop3h 41m
Thu 12/107:26 pm -
1 stop4h 28m
Deal found 10/27![Delta logo]()
$285
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/11:15 pm -
2 stops6h 35m
Tue 12/81:00 pm -
2 stops7h 05m
Deal found 10/25![Southwest logo]()
$275
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/22:20 pm -
Nonstop1h 53m
Mon 1/46:00 am -
Nonstop2h 11m
Deal found 10/26![United Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/185:55 pm -
1 stop4h 51m
Sun 2/2111:30 am -
1 stop6h 07m
Deal found 10/29![Delta logo]()
$302
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/910:38 am -
1 stop8h 21m
Wed 11/1110:55 am -
1 stop22h 45m
Deal found 10/28![Allegiant Air logo]()
$346
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/91:15 pm -
2 stops6h 35m
Sun 12/137:25 pm -
1 stop5h 45m
Deal found 10/26![Southwest logo]()
$290
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/91:34 pm -
1 stop5h 40m
Sun 12/136:17 pm -
1 stop6h 39m
Deal found 10/26![Delta logo]()
$302
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/412:45 pm -
1 stop6h 05m
Sun 12/67:25 pm -
1 stop5h 45m
Deal found 10/29![Southwest logo]()
$293
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/186:00 am -
1 stop4h 06m
Sun 2/217:30 am -
1 stop6h 03m
Deal found 10/26![Delta logo]()
$302
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/101:44 pm -
1 stop28h 27m
Thu 12/109:05 pm -
1 stop13h 21m
Deal found 10/27![Allegiant Air logo]()
$379
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/198:50 am -
1 stop4h 58m
Tue 11/246:45 am -
Nonstop2h 09m
Deal found 10/25![United Airlines logo]()
$388
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/238:45 am -
2 stops7h 05m
Mon 11/237:25 pm -
1 stop5h 45m
Deal found 10/28![Southwest logo]()
$310
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/910:38 am -
1 stop24h 57m
Thu 12/109:05 pm -
1 stop13h 21m
Deal found 10/27![Allegiant Air logo]()
$381
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/143:00 pm -
1 stop6h 12m
Sat 11/214:00 pm -
1 stop5h 49m
Deal found 10/25![Delta logo]()
$329
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/28:00 am -
1 stop3h 20m
Thu 12/35:15 pm -
1 stop6h 30m
Deal found 10/26![Southwest logo]()
$311
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/311:00 pm -
1 stop5h 49m
Sun 1/36:00 am -
Nonstop2h 11m
Deal found 10/26![United Airlines logo]()
$417
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:03 pm -
2 stops38h 02m
Fri 11/136:56 pm -
1 stop17h 58m
Deal found 10/25![Multiple Airlines logo]()
$528
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/26:25 am -
1 stop6h 14m
Mon 1/45:15 am -
1 stop4h 25m
Deal found 10/26![Delta logo]()
$329
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/38:00 am -
1 stop3h 20m
Thu 12/35:15 pm -
1 stop6h 30m
Deal found 10/26![Southwest logo]()
$311
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/259:07 am -
1 stop10h 41m
Sun 2/146:35 pm -
1 stop15h 27m
Deal found 10/27![Allegiant Air logo]()
$420
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1510:30 am -
Nonstop1h 50m
Wed 12/166:20 am -
2 stops11h 31m
Deal found 10/26![United Airlines logo]()
$424
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/111:10 am -
1 stop3h 58m
Sun 4/45:30 am -
1 stop5h 32m
Deal found 10/29![Delta logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/2811:23 am -
1 stop21h 24m
Fri 2/127:10 am -
1 stop10h 42m
Deal found 10/27![Allegiant Air logo]()
$425
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/169:00 am -
1 stop5h 52m
Thu 11/195:40 pm -
Nonstop2h 03m
Deal found 10/26![United Airlines logo]()
$447
Last-minute flights from Chicago to KnoxvilleDiscover last-minute flight deals from Chicago to Knoxville. Data last updated October 30, 2026 and is based on user searches.
Discover last-minute flight deals from Chicago to Knoxville. Data last updated October 30, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/302:26 pm -
Nonstop1h 25m
Sun 11/14:57 pm -
1 stop25h 57m
Deal found 10/26![Allegiant Air logo]()
$280
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/94:31 pm -
Nonstop1h 30m
Wed 11/1110:55 am -
2 stops13h 52m
Deal found 10/27![Multiple Airlines logo]()
$268
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/133:16 pm -
Nonstop1h 30m
Mon 11/168:44 pm -
2 stops28h 03m
Deal found 10/28![Multiple Airlines logo]()
$266
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/164:31 pm -
Nonstop1h 30m
Tue 11/176:08 pm -
3 stops24h 39m
Deal found 10/28![Multiple Airlines logo]()
$284
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/219:00 pm -
Nonstop1h 50m
Wed 11/258:50 pm -
Nonstop2h 09m
Deal found 10/28![American Airlines logo]()
$265
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:49 am -
1 stop6h 06m
Tue 12/17:10 am -
1 stop4h 49m
Deal found 10/26![Delta logo]()
$277
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:19 am -
1 stop4h 14m
Fri 11/277:01 am -
1 stop6h 59m
Deal found 10/29![American Airlines logo]()
$281
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/254:08 pm -
Nonstop1h 44m
Mon 11/308:50 pm -
Nonstop2h 09m
Deal found 10/28![American Airlines logo]()
$270
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/254:08 pm -
Nonstop1h 44m
Fri 11/277:01 am -
1 stop5h 43m
Deal found 10/28![American Airlines logo]()
$275
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/274:00 pm -
1 stop3h 35m
Mon 12/75:15 pm -
1 stop6h 30m
Deal found 10/28![Southwest logo]()
$265
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/278:05 am -
1 stop4h 21m
Fri 12/47:44 am -
Nonstop2h 26m
Deal found 10/28![American Airlines logo]()
$271
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/285:19 am -
1 stop4h 14m
Sat 12/54:24 pm -
Nonstop2h 05m
Deal found 10/29![American Airlines logo]()
$280
One-way flights from Chicago to KnoxvilleSearch for one-way flight options from Chicago to Knoxville. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
Search for one-way flight options from Chicago to Knoxville. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/94:31 pm -
Nonstop1h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![Allegiant Air logo]()
$56
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/133:16 pm -
Nonstop1h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Allegiant Air logo]()
$62
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/239:29 am -
Nonstop1h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Allegiant Air logo]()
$69
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:09 pm -
Nonstop1h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![Allegiant Air logo]()
$106
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/238:09 am -
Nonstop1h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![American Airlines logo]()
$111
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/232:44 pm -
1 stop5h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![Delta logo]()
$121
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:00 am -
1 stop4h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Delta logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/129:30 am -
1 stop12h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![Allegiant Air logo]()
$123
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/189:32 pm -
Nonstop1h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![American Airlines logo]()
$123
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/89:55 am -
2 stops9h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Southwest logo]()
$126
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/271:20 pm -
Nonstop1h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![American Airlines logo]()
$131
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/138:31 am -
Nonstop1h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![American Airlines logo]()
$135
Find flight deals from Chicago to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Chicago (CHI) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $255 (Kiwi.com) |
One-way from | $56 (Kiwi.com) |
Popular in | September |
Cheapest in | June |
Average price | $337 |
Good round-trip deal | $106 or less |
Good one-way deal | $122 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Chicago to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
Use the filters below to find and compare flights from Chicago to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoKnoxville
ORD Chicago O'Hare Intl - TYS Knoxville McGhee Tyson
ORDTYS
Chicago O'Hare Intl
Wed 12/9
2:10 pm-5:00 pm
Nonstop1h 50m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$111
ChicagoKnoxville
MDW Chicago Midway - TYS Knoxville McGhee Tyson
MDWTYS
Chicago Midway
Mon 11/23
6:00 am-11:28 am
1 stop4h 28m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$121
ChicagoKnoxville
MDW Chicago Midway - TYS Knoxville McGhee Tyson
MDWTYS
Chicago Midway
Tue 12/8
8:05 am-3:30 pm
1 stop6h 25m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$121
ChicagoKnoxville
ORD Chicago O'Hare Intl - TYS Knoxville McGhee Tyson
ORDTYS
Chicago O'Hare Intl
Fri 11/27
1:20 pm-4:02 pm
Nonstop1h 42m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$131
ChicagoKnoxville
RFD Chicago Greater Rockford - TYS Knoxville McGhee Tyson
RFDTYS
Chicago Greater Rockford
Thu 11/12
9:30 am-10:37 pm
1 stop12h 07m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$132
ChicagoKnoxville
MDW Chicago Midway - TYS Knoxville McGhee Tyson
MDWTYS
Chicago Midway
Fri 12/25
1:15 pm-8:50 pm
2 stops6h 35m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$142
ChicagoKnoxville
ORD Chicago O'Hare Intl - TYS Knoxville McGhee Tyson
ORDTYS
Chicago O'Hare Intl
Thu 1/14
3:24 pm-1:44 pm
1 stop21h 20m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$148
ChicagoKnoxville
ORD Chicago O'Hare Intl - TYS Knoxville McGhee Tyson
ORDTYS
Chicago O'Hare Intl
Sun 11/22
5:59 pm-8:54 pm
Nonstop1h 55m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$155
ChicagoKnoxville
MDW Chicago Midway - TYS Knoxville McGhee Tyson
MDWTYS
Chicago Midway
Sun 11/22
5:05 am-10:40 am
1 stop4h 35m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$165
ChicagoKnoxville
MDW Chicago Midway - TYS Knoxville McGhee Tyson
MDWTYS
Chicago Midway
Sun 12/13
10:10 am-6:45 pm
2 stops7h 35m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$170
Showing 1-10 of 60 resultsSorted by cheapest first
Compare providers for flights from Chicago to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Chicago to Knoxville in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Chicago-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Chicago-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Chicago-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Chicago-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Chicago to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Chicago with our price prediction graph.
CHI-TYS
MDW-TYS
ORD-TYS
RFD-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago to Knoxville
CHI-TYS
MDW-TYS
ORD-TYS
RFD-TYS
What is the cheapest month to book a flight from Chicago to Knoxville?
Currently, June is the cheapest month in which you can book a flight from Chicago to Knoxville (average of $257). Flying from Chicago to Knoxville in September is currently the most expensive (average of $382). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from CHI to TYS?
Find hourly flight availability from Chicago to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2026.
Unlike in the afternoon, when flights are generally more expensive, you can save up to 23% on flights from Chicago to Knoxville by exploring options for tickets at noon.
How much does it cost to fly round-trip from Chicago to Knoxville?
Airfare is below average for this route at the moment.
Chicago to Knoxville flights typically cost between $257 and $379 in November.The cheapest round-trip price found within the last 5 days was $255 on Multiple Airlines (Nov 13-Nov 21).
How far ahead should I book a flight from Chicago to Knoxville?
Booking 74 days in advance of your planned departure date is, on average, the best time to get cheap flights from Chicago to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest day to fly from Chicago to Knoxville?
Use this chart to determine the cheapest time to fly round-trip from Chicago to Knoxville. Price data was last updated on October 24, 2026.
Travelers seeking maximum savings on their Chicago to Knoxville flight should consider departing on Tuesday at noon when fares are most often at their lowest. Sunday mornings flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated October 30, 2026.
Read through reviews of airlines operating flights from Chicago to Knoxville, such as Southwest,United Airlines, andAllegiant Air. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.4
Food
7.0
Crew
8.6
Overall
7.9
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentJohn,May 2025
PVD - BNA
Entertainment
7.4
Food
7.0
Crew
8.6
Overall
7.9
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentJohn,May 2025
PVD - BNA
Entertainment
7.4
Food
7.0
Crew
8.6
Overall
7.9
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentJohn,May 2025
PVD - BNA
Entertainment
7.4
Food
7.0
Crew
8.6
Overall
7.9
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentJohn,May 2025
PVD - BNA
Entertainment
7.4
Food
7.0
Crew
8.6
Overall
7.9
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentJohn,May 2025
PVD - BNA
Related info for your journey
Find useful and relevant information for your journey from Chicago to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Morristown
Newport
Bryson City
Crossville
Murphy
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Other flights to Knoxville
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Browse through other flights departing from Chicago. Flights are based on user searches made on Cheapflights and were last updated on October 30, 2026.
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Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from Chicago to Knoxville
Discover the top 4 airlines that operate flights from Chicago to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$82 | Average$151 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$161 | Average$413 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$188 | Average$360 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$189 | Average$354 | FlexibilityNo cancel fee | On-time69% |