What are the cheapest airlines flying from Chicago to Knoxville round-trip?

Our cheapest airline available from Chicago to Knoxville is Allegiant Air. Our recent data shows that you can find tickets from as low as $77 on this airline. Additional options worth looking into are American Airlines and Delta, starting at $179 and $188 round-trip. Allegiant Air is priced at 71% lower than the current average price of a flight leaving 3 months from now.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

What are the cheapest flights from Chicago to Knoxville?

While on average a flight from Chicago to Knoxville is generally $452, our data shows the cheapest flight currently is $189. When looking at the most popular route, (Chicago O'Hare Intl - Knoxville McGhee Tyson), you can expect to pay $189 for that flight.

What are the most reliable airlines from Chicago to Knoxville?

No one likes to see their flight delayed. When booking a flight from Chicago to Knoxville consider choosing Republic Airways (92%), United Airlines (72%) or SkyWest Airlines (72%) as they are the most reliable in getting you off to your destination on time.

What is the cheapest day to fly round-trip from Chicago to Knoxville?

Users have found that flying from Chicago to Knoxville on a Saturday typically leans towards higher prices. However, this doesn’t mean you still can’t find a deal. Flexibility with other aspects of your flight can still land a great price for your trip.

How far in advance should I book a flight from Chicago to Knoxville?

To save up to 83% on this flight, we recommend booking at least 58 days prior to travel. The price may fluctuate and will likely increase closer to your departure date. Users on Cheapflights have found tickets from Chicago to Knoxville from $259 1-2 weeks out and tickets from $359 for flights departing within the next 72 hours.

What is the cheapest month to fly from Chicago to Knoxville?

The best pricing can be found in the month of September. Prices to Knoxville from Chicago average $272. You can even find prices in September for less than $272, as users have found deals to Knoxville from as low as $79. The month of December appears to be one of the more expensive times to travel to Knoxville from Chicago. Flying in the targeted month can save you up to 22%.

What airport do you fly into for flights to Knoxville from Chicago?

Located just 11.3 mi from the city center, Knoxville McGhee Tyson is the airport most travelers will use when flying to Knoxville from Chicago. Booking flights from Chicago to McGhee Tyson (TYS) should be relatively easy as there are 20 daily inbound flights from Chicago from 4 different airlines.

Can I find deals for flights from Chicago to Knoxville that include hotel bookings?

Yes. In addition to deals on Chicago to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Chicago to Knoxville?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Chicago to Knoxville.

Can I find deals for business class flights from Chicago to Knoxville?

Yes. Cheapflights offers flight deals from Chicago to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$49+ Flights from Chicago to Knoxville

Q: How much does it cost to fly round-trip from Chicago to Knoxville?

Airfare is below average for this route at the moment. Chicago to Knoxville flights typically cost between $189 and $324 in September. The cheapest round-trip price found within the last 3 days was $119 on Allegiant Air (Sep 26-Sep 29).

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Chicago to Knoxville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Chicago to Knoxville McGhee Tyson are usually found in September or January, booked 73 days in advance, depart on a Wednesday or Friday and return on a Friday

Cheap flight deals from Chicago to Knoxville

Round-trip from	$119 (Cheapflightsfares)
One-way from	$53 (Mytrip)
Popular in	December
Cheapest in	September
Average price	$249
Good round-trip deal	$89 or less
Good one-way deal	$51 or less

From Chicago (CHI) to Knoxville McGhee Tyson

Search Deals

One-way flight from Chicago (CHI) to Knoxville McGhee Tyson

Search Deals

Highest demand for flights based on searches. 2% potential increase in price ($6 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($6 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in August 2025

Search Deals

Price to beat on a round-trip flight from Chicago (CHI) to Knoxville McGhee Tyson.

Search Deals

Price to beat on a one-way flight from Chicago (CHI) to Knoxville McGhee Tyson.

Search Deals

Find flight deals from Chicago to Knoxville

Cheapest flights from Chicago to Knoxville
Explore the most affordable flight options available from Chicago to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on août 14, 2025.

ven. 9/267:50 pmMDW - TYS

Nonstop1h 31mAllegiant Air

lun. 9/291:50 pmTYS - MDW

Nonstop1h 36mAllegiant Air

Deal found 8/14

$119

ven. 9/197:50 pmMDW - TYS

Nonstop1h 31mAllegiant Air

ven. 10/310:44 amTYS - MDW

Nonstop1h 32mAllegiant Air

Deal found 8/13

$125

ven. 9/197:50 pmMDW - TYS

Nonstop1h 31mAllegiant Air

lun. 9/226:24 pmTYS - MDW

Nonstop1h 36mAllegiant Air

Deal found 8/12

$128

ven. 10/312:06 pmMDW - TYS

Nonstop1h 24mAllegiant Air

lun. 10/610:46 amTYS - MDW

Nonstop1h 32mAllegiant Air

Deal found 8/12

$158

ven. 10/242:45 pmMDW - TYS

Nonstop1h 24mAllegiant Air

lun. 10/277:02 pmTYS - MDW

Nonstop1h 32mAllegiant Air

Deal found 8/12

$170

jeu. 9/410:42 amORD - TYS

1 stop8h 08mFrontier

lun. 9/88:35 pmTYS - ORD

1 stop25h 53mFrontier

Deal found 8/14

$179

ven. 9/127:50 pmMDW - TYS

Nonstop1h 31mMultiple Airlines

ven. 9/191:22 pmTYS - MDW

1 stop21h 29mMultiple Airlines

Deal found 8/13

$181

lun. 8/253:52 pmMDW - TYS

Nonstop1h 28mAllegiant Air

lun. 9/12:29 pmTYS - MDW

Nonstop1h 33mAllegiant Air

Deal found 8/12

$188

jeu. 9/46:14 pmORD - TYS

Nonstop1h 46mAmerican Airlines

lun. 9/84:49 pmTYS - ORD

Nonstop2h 01mAmerican Airlines

Deal found 8/12

$189

ven. 9/269:48 amMDW - TYS

1 stop6h 46mMultiple Airlines

lun. 9/291:50 pmTYS - MDW

Nonstop1h 36mMultiple Airlines

Deal found 8/12

$191

mer. 8/271:55 pmORD - TYS

Nonstop1h 41mAmerican Airlines

mar. 9/212:56 pmTYS - ORD

Nonstop1h 53mAmerican Airlines

Deal found 8/13

$199

mer. 9/105:05 amORD - TYS

1 stop9h 36mMultiple Airlines

mer. 9/174:31 pmTYS - ORD

1 stop7h 17mMultiple Airlines

Deal found 8/11

$206

Best flights from Chicago to Knoxville
Discover carefully curated flight deals from Chicago to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated août 14, 2025.

ven. 9/267:50 pmMDW - TYS

Nonstop1h 31mAllegiant Air

lun. 9/291:50 pmTYS - MDW

Nonstop1h 36mAllegiant Air

Deal found 8/14

$119

ven. 9/127:50 pmMDW - TYS

Nonstop1h 31mMultiple Airlines

ven. 9/191:22 pmTYS - MDW

1 stop21h 29mMultiple Airlines

Deal found 8/13

$181

jeu. 9/410:42 amORD - TYS

1 stop8h 08mFrontier

lun. 9/88:35 pmTYS - ORD

1 stop25h 53mFrontier

Deal found 8/13

$184

mar. 9/91:37 pmORD - TYS

Nonstop1h 42mAmerican Airlines

mar. 9/163:56 pmTYS - ORD

Nonstop2h 08mAmerican Airlines

Deal found 8/12

$189

ven. 10/312:06 pmMDW - TYS

Nonstop1h 24mAllegiant Air

lun. 10/610:46 amTYS - MDW

Nonstop1h 32mAllegiant Air

Deal found 8/12

$125

ven. 9/197:50 pmMDW - TYS

Nonstop1h 31mAllegiant Air

ven. 10/310:44 amTYS - MDW

Nonstop1h 32mAllegiant Air

Deal found 8/13

$125

ven. 9/197:50 pmMDW - TYS

Nonstop1h 31mAllegiant Air

lun. 9/226:24 pmTYS - MDW

Nonstop1h 36mAllegiant Air

Deal found 8/12

$128

ven. 9/51:37 pmORD - TYS

Nonstop1h 42mAmerican Airlines

lun. 9/84:49 pmTYS - ORD

Nonstop2h 01mAmerican Airlines

Deal found 8/12

$189

mer. 9/1012:20 pmORD - TYS

Nonstop1h 46mAmerican Airlines

sam. 9/134:49 pmTYS - ORD

Nonstop2h 01mAmerican Airlines

Deal found 8/12

$189

ven. 10/242:45 pmMDW - TYS

Nonstop1h 24mAllegiant Air

lun. 10/277:02 pmTYS - MDW

Nonstop1h 32mAllegiant Air

Deal found 8/12

$170

mar. 9/1611:59 amORD - TYS

Nonstop1h 47mAmerican Airlines

sam. 9/203:10 pmTYS - ORD

Nonstop2h 00mAmerican Airlines

Deal found 8/12

$189

mer. 9/36:14 pmORD - TYS

Nonstop1h 46mAmerican Airlines

sam. 9/63:10 pmTYS - ORD

Nonstop2h 00mAmerican Airlines

Deal found 8/12

$189

Last-minute flights from Chicago to Knoxville
Discover last-minute flight deals from Chicago to Knoxville. Data last updated août 14, 2025 and is based on user searches.

mar. 8/198:47 pmORD - TYS

2 stops18h 59mMultiple Airlines

mar. 8/269:00 amTYS - ORD

2 stops14h 22mMultiple Airlines

Deal found 8/12

$300

mar. 8/197:47 pmORD - TYS

Nonstop1h 50mUnited Airlines

mar. 8/269:55 amTYS - ORD

1 stop5h 34mUnited Airlines

Deal found 8/12

$308

jeu. 8/2111:36 amORD - TYS

2 stops25h 03mMultiple Airlines

dim. 8/249:12 pmTYS - ORD

2 stops14h 14mMultiple Airlines

Deal found 8/14

$278

jeu. 8/216:29 pmORD - TYS

Nonstop1h 44mAmerican Airlines

dim. 8/245:38 pmTYS - ORD

Nonstop1h 58mAmerican Airlines

Deal found 8/12

$299

jeu. 8/216:04 amMDW - TYS

1 stop6h 04mDelta

dim. 8/245:45 amTYS - MDW

1 stop4h 51mDelta

Deal found 8/12

$314

ven. 8/223:52 pmMDW - TYS

Nonstop1h 28mAllegiant Air

dim. 8/2411:00 amTYS - MDW

2 stops22h 42mAllegiant Air

Deal found 8/14

$245

ven. 8/227:18 amORD - TYS

Nonstop1h 55mUnited Airlines

dim. 8/245:35 pmTYS - ORD

Nonstop2h 02mUnited Airlines

Deal found 8/14

$249

ven. 8/227:18 amORD - TYS

Nonstop1h 55mUnited Airlines

lun. 8/252:30 pmTYS - ORD

1 stop6h 18mUnited Airlines

Deal found 8/12

$259

ven. 8/226:42 pmMDW - TYS

1 stop4h 06mDelta

lun. 8/255:45 amTYS - MDW

1 stop4h 51mDelta

Deal found 8/12

$269

ven. 8/229:17 amMDW - TYS

1 stop7h 21mMultiple Airlines

lun. 8/252:29 pmTYS - MDW

Nonstop1h 33mMultiple Airlines

Deal found 8/12

$272

ven. 8/223:52 pmMDW - TYS

Nonstop1h 28mMultiple Airlines

dim. 8/241:52 pmTYS - MDW

1 stop11h 53mMultiple Airlines

Deal found 8/13

$303

ven. 8/2211:53 amORD - TYS

Nonstop1h 41mAmerican Airlines

dim. 8/245:38 pmTYS - ORD

Nonstop1h 58mAmerican Airlines

Deal found 8/14

$317

One-way flights from Chicago to Knoxville
Search for one-way flight options from Chicago to Knoxville. Find affordable one-way fares based on user searches. Data last updated août 14, 2025.

lun. 9/157:50 pmMDW - TYS

Nonstop1h 31mAllegiant Air

Deal found 8/14

$53

ven. 9/197:50 pmMDW - TYS

Nonstop1h 31mAllegiant Air

Deal found 8/13

$62

dim. 9/76:00 amORD - TYS

1 stop9h 18mFrontier

Deal found 8/14

$84

ven. 8/292:09 pmMDW - TYS

Nonstop1h 28mAllegiant Air

Deal found 8/14

$92

mer. 9/175:05 amORD - TYS

1 stop9h 36mMultiple Airlines

Deal found 8/12

$99

mar. 9/911:57 amORD - TYS

1 stop26h 44mMultiple Airlines

Deal found 8/12

$111

jeu. 8/2111:44 amORD - TYS

1 stop6h 57mFrontier

Deal found 8/14

$112

jeu. 9/1110:42 amORD - TYS

1 stop8h 08mFrontier

Deal found 8/14

$115

mer. 9/105:05 amORD - TYS

1 stop9h 36mMultiple Airlines

Deal found 8/14

$117

lun. 9/157:15 amMDW - TYS

2 stops11h 30mFrontier

Deal found 8/14

$117

sam. 9/65:05 amORD - TYS

1 stop29h 13mMultiple Airlines

Deal found 8/13

$119

jeu. 9/1812:05 pmORD - TYS

1 stop9h 14mMultiple Airlines

Deal found 8/13

$126

Fly from

Fly to

Route

Depart

Return

Price

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

ven. 9/26

7:50 pm-10:21 pm

Nonstop1h 31m

Knoxville McGhee Tyson

lun. 9/29

1:50 pm-2:26 pm

Nonstop1h 36m

$119

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

ven. 10/3

12:06 pm-2:30 pm

Nonstop1h 24m

Knoxville McGhee Tyson

lun. 10/6

10:46 am-11:18 am

Nonstop1h 32m

$125

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

ven. 9/19

7:50 pm-10:21 pm

Nonstop1h 31m

Knoxville McGhee Tyson

ven. 10/3

10:44 am-11:16 am

Nonstop1h 32m

$125

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

ven. 9/19

7:50 pm-10:21 pm

Nonstop1h 31m

Knoxville McGhee Tyson

lun. 9/22

6:24 pm-7:00 pm

Nonstop1h 36m

$128

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

ven. 10/24

2:45 pm-5:09 pm

Nonstop1h 24m

Knoxville McGhee Tyson

lun. 10/27

7:02 pm-7:34 pm

Nonstop1h 32m

$170

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

ven. 9/12

7:50 pm-10:21 pm

Nonstop1h 31m

Knoxville McGhee Tyson

ven. 9/19

1:22 pm-9:51 am

1 stop21h 29m

$181

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

jeu. 9/4

10:42 am-7:50 pm

1 stop8h 08m

Knoxville McGhee Tyson

lun. 9/8

8:35 pm-9:28 pm

1 stop25h 53m

$184

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

lun. 8/25

3:52 pm-6:20 pm

Nonstop1h 28m

Knoxville McGhee Tyson

lun. 9/1

2:29 pm-3:02 pm

Nonstop1h 33m

$188

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

mar. 9/9

1:37 pm-4:19 pm

Nonstop1h 42m

Knoxville McGhee Tyson

mar. 9/16

3:56 pm-5:04 pm

Nonstop2h 08m

$189

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

ven. 9/5

1:37 pm-4:19 pm

Nonstop1h 42m

Knoxville McGhee Tyson

lun. 9/8

4:49 pm-5:50 pm

Nonstop2h 01m

$189

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/12

Showing 1-10 of 35 results

Best time to book a flight from Chicago to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Chicago with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago to Knoxville

How far ahead should I book a flight from Chicago to Knoxville?

Booking 73 days in advance of your planned departure date is, on average, the best time to get cheap flights from Chicago to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Chicago to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Chicago to Knoxville (average of $294). Flying from Chicago to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHI to TYS?

Unlike in the morning, when flights are generally more expensive, you can save up to 10% on flights from Chicago to Knoxville by exploring options for tickets at noon.

What is the cheapest day to fly from Chicago to Knoxville?

Travelers seeking maximum savings on their Chicago to Knoxville flight should consider departing on Friday at noon when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Chicago to Knoxville

The most flights from CHI to TYS are scheduled on a Wednesday (26 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (10 on average).

How much does it cost to fly round-trip from Chicago to Knoxville?

Reviews of airlines servicing Knoxville

Read through reviews of airlines operating flights from Chicago to Knoxville, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,980 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,980 reviews

Delta

8.0

Very good

7,980 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

United Airlines

7.4

Good

8,916 reviews

Delta

8.0

Very good

7,980 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,980 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Allegiant Air

7.2

Good

701 reviews

Delta

8.0

Very good

7,980 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

What airport do you fly into for flights to Knoxville from Chicago?
Located just 11.3 mi from the city center, Knoxville McGhee Tyson is the airport most travelers will use when flying to Knoxville from Chicago. Booking flights from Chicago to McGhee Tyson (TYS) should be relatively easy as there are 20 daily inbound flights from Chicago from 4 different airlines.
What are the cheapest airlines flying from Chicago to Knoxville round-trip?
Our cheapest airline available from Chicago to Knoxville is Allegiant Air. Our recent data shows that you can find tickets from as low as $77 on this airline. Additional options worth looking into are American Airlines and Delta, starting at $179 and $188 round-trip. Allegiant Air is priced at 71% lower than the current average price of a flight leaving 3 months from now.
What are the most reliable airlines from Chicago to Knoxville?
No one likes to see their flight delayed. When booking a flight from Chicago to Knoxville consider choosing Republic Airways (92%), United Airlines (72%) or SkyWest Airlines (72%) as they are the most reliable in getting you off to your destination on time.
What are the cheapest flights from Chicago to Knoxville?
While on average a flight from Chicago to Knoxville is generally $452, our data shows the cheapest flight currently is $189. When looking at the most popular route, (Chicago O'Hare Intl - Knoxville McGhee Tyson), you can expect to pay $189 for that flight.
Can I find deals for flights from Chicago to Knoxville that include hotel bookings?
Yes. In addition to deals on Chicago to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Chicago to Knoxville?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Chicago to Knoxville.
Can I find deals for business class flights from Chicago to Knoxville?
Yes. Cheapflights offers flight deals from Chicago to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Chicago to Knoxville?
Currently, January is the cheapest month in which you can book a flight from Chicago to Knoxville (average of $294). Flying from Chicago to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Morristown

Cherokee

Corbin

Alcoa

Oak Ridge

Murphy

Browse thousands of different options on Cheapflights for your next trip

Top 4 airlines flying from Chicago to Knoxville

Airline	Cheapest	Average	Flexibility	On-time
Allegiant Air	Cheapest$77	Average$115	FlexibilityNo cancel fee	On-time88%
American Airlines	Cheapest$179	Average$292	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$188	Average$335	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$189	Average$322	FlexibilityNo cancel fee	On-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$49+ Cheap flights from Chicago (CHI) to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/5. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Chicago to Knoxville with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Chicago to Knoxville McGhee Tyson are usually found in September or January, booked 73 days in advance, depart on a Wednesday or Friday and return on a Friday

Cheap flight deals from Chicago to Knoxville

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Find flight deals from Chicago to Knoxville

Cheapest flights from Chicago to KnoxvilleExplore the most affordable flight options available from Chicago to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on août 14, 2025.

Explore the most affordable flight options available from Chicago to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on août 14, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Chicago to Knoxville that are best for you.

Best time to book a flight from Chicago to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Chicago with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Chicago to Knoxville

How far ahead should I book a flight from Chicago to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from Chicago to Knoxville. Price data was last updated on August 8, 2025.

What is the cheapest month to book a flight from Chicago to Knoxville?

What is the cheapest time of day to fly from CHI to TYS?

Find hourly flight availability from Chicago to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated août 14, 2025.

What is the cheapest day to fly from Chicago to Knoxville?

Use this chart to determine the cheapest time to fly round-trip from Chicago to Knoxville. Price data was last updated on December 16, 2024.

Weekly flight availability from Chicago to Knoxville

Explore weekly flight availability from Chicago to Knoxville. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated août 14, 2025.

How much does it cost to fly round-trip from Chicago to Knoxville?

Reviews of airlines servicing Knoxville

Read through reviews of airlines operating flights from Chicago to Knoxville, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Chicago to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Knoxville from Chicago?

What are the cheapest airlines flying from Chicago to Knoxville round-trip?

What are the most reliable airlines from Chicago to Knoxville?

What are the cheapest flights from Chicago to Knoxville?

Can I find deals for flights from Chicago to Knoxville that include hotel bookings?

How can I find direct flights from Chicago to Knoxville?

Can I find deals for business class flights from Chicago to Knoxville?

What is the cheapest month to book a flight from Chicago to Knoxville?

Traveling to a place near Knoxville?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Chicago to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Chicago to Knoxville

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Chicago to Knoxville
Explore the most affordable flight options available from Chicago to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on août 14, 2025.