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$140+ Cheap flights from Syracuse to Key West (SYR - EYW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/4. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — EYW
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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1. Tell us where you want to go

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Cheapflights Tip: The best prices from Syracuse Hancock Intl to Key West are usually found in August or June, booked 35 days in advance, depart on a Tuesday or Sunday and return on a Wednesday

Cheap flight deals from Syracuse to Key West

Discover tips and strategies to find the most affordable flight options for your journey from Syracuse (SYR) to Key West (EYW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2025.

Round-trip from

$269
(American Airlines)

One-way from

$140
(American Airlines)

Popular in

April

Cheapest in

August

Average price

$408
From Syracuse Hancock Intl to Key West
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One-way flight from Syracuse Hancock Intl to Key West
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Highest demand for flights based on searches. 16% potential increase in price ($84 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($21 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Syracuse to Key West

Cheapest flights from Syracuse to Key West
Explore the most affordable flight options available from Syracuse to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/156:00 amSYR - EYW
1 stop6h 58mAmerican Airlines
Tue 10/214:58 pmEYW - SYR
1 stop5h 53mAmerican Airlines
Deal found 9/15$269
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/156:00 amSYR - EYW
1 stop6h 58mAmerican Airlines
Wed 10/2211:22 amEYW - SYR
2 stops12h 00mAmerican Airlines
Deal found 9/15$274
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/41:42 pmSYR - EYW
1 stop8h 03mAmerican Airlines
Mon 12/87:00 amEYW - SYR
2 stops7h 16mAmerican Airlines
Deal found 9/16$299
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/711:07 amSYR - EYW
1 stop22h 05mMultiple Airlines
Tue 10/1411:45 amEYW - SYR
2 stops47h 36mMultiple Airlines
Deal found 9/15$303
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/411:34 amSYR - EYW
1 stop8h 26mMultiple Airlines
Mon 12/88:55 amEYW - SYR
1 stop9h 24mMultiple Airlines
Deal found 9/15$306
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/305:32 amSYR - EYW
1 stop6h 17mAmerican Airlines
Sat 10/412:24 pmEYW - SYR
1 stop4h 45mAmerican Airlines
Deal found 9/15$319
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/912:16 pmSYR - EYW
2 stops21h 01mMultiple Airlines
Sun 10/128:55 amEYW - SYR
1 stop11h 15mMultiple Airlines
Deal found 9/15$321
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/912:16 pmSYR - EYW
2 stops21h 01mMultiple Airlines
Mon 10/133:56 pmEYW - SYR
1 stop18h 21mMultiple Airlines
Deal found 9/15$323
This JetBlue deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/126:00 amSYR - EYW
1 stop6h 09mJetBlue
Thu 10/161:04 pmEYW - SYR
1 stop7h 16mJetBlue
Deal found 9/15$327

Cheapflights Fare Finder

 
Customize your flight search to find flights from Syracuse to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Syracuse to Key West that are best for you.

Fly from

Syracuse

Fly to

Key West

Route

Depart

Return

Price

SyracuseKey West

SYR - EYW

SYREYW

Syracuse Hancock Intl

Thu 11/13

1:42 pm-9:47 pm

1 stop8h 05m

Key West

Tue 11/18

7:31 am-2:15 pm

1 stop6h 44m

$269

SyracuseKey West

SYR - EYW

SYREYW

Syracuse Hancock Intl

Wed 10/15

6:00 am-12:58 pm

1 stop6h 58m

Key West

Tue 10/21

4:58 pm-10:51 pm

1 stop5h 53m

$269

SyracuseKey West

SYR - EYW

SYREYW

Syracuse Hancock Intl

Sat 11/8

12:10 pm-9:49 pm

2 stops9h 39m

Key West

Wed 11/12

5:09 pm-10:39 pm

1 stop5h 30m

$274

SyracuseKey West

SYR - EYW

SYREYW

Syracuse Hancock Intl

Tue 10/7

11:07 am-9:12 am

1 stop22h 05m

Key West

Tue 10/14

11:45 am-11:21 am

2 stops47h 36m

$303

SyracuseKey West

SYR - EYW

SYREYW

Syracuse Hancock Intl

Thu 12/4

11:34 am-8:00 pm

1 stop8h 26m

Key West

Mon 12/8

8:55 am-6:19 pm

1 stop9h 24m

$306

SyracuseKey West

SYR - EYW

SYREYW

Syracuse Hancock Intl

Sat 10/18

2:17 pm-8:06 pm

1 stop5h 49m

Key West

Tue 10/21

6:17 pm-12:20 am

1 stop6h 03m

$324

SyracuseKey West

SYR - EYW

SYREYW

Syracuse Hancock Intl

Sun 10/12

6:00 am-12:09 pm

1 stop6h 09m

Key West

Thu 10/16

1:04 pm-8:20 pm

1 stop7h 16m

$327

SyracuseKey West

SYR - EYW

SYREYW

Syracuse Hancock Intl

Sat 9/27

5:55 am-1:02 pm

1 stop7h 07m

Key West

Wed 10/1

6:10 pm-11:59 pm

1 stop5h 49m

$334

SyracuseKey West

SYR - EYW

SYREYW

Syracuse Hancock Intl

Thu 12/4

1:42 pm-9:45 pm

1 stop8h 03m

$140

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/17

Best time to book a flight from Syracuse to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from Syracuse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to Key West

How far ahead should I book a flight from Syracuse to Key West?

Use this chart to determine the optimal time to book a round-trip flight from Syracuse to Key West. Price data was last updated on September 12, 2025.

The best time to book flights from Syracuse to Key West is 35 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Syracuse to Key West?

Currently, August is the cheapest month in which you can book a flight from Syracuse to Key West (average of $328). Flying from Syracuse to Key West in March is currently the most expensive (average of $491). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Key West

Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated September 17, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Syracuse to Key West by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,961 reviews

Boarding

8.2

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
8.0
Very good
7,961 reviews
Delta
8.0
Very good
7,961 reviews

Boarding

8.2

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
United Airlines
7.4
Good
8,926 reviews
Delta
8.0
Very good
7,961 reviews

Boarding

8.2

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,961 reviews

Boarding

8.2

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
JetBlue
7.2
Good
2,914 reviews
Delta
8.0
Very good
7,961 reviews

Boarding

8.2

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Syracuse to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Syracuse to Key West?

    For as low as $269, American Airlines can have you in Key West from Syracuse in 8h 05m. There are 1321 mi between Syracuse and Key West.

  • What are the cheapest airlines flying from Syracuse to Key West round-trip?

    Flying on JetBlue is currently your cheapest option to Key West, with prices starting at $201. Additional round-trip tickets that might be worth considering are offered by United Airlines and American Airlines, with the lowest prices starting at $216 and $216, respectively. JetBlue is currently priced 53% below the average price you’ll pay for this route.

  • Can I find deals for flights from Syracuse to Key West that include hotel bookings?

    Yes. In addition to deals on Syracuse to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Syracuse to Key West?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to Key West.

  • Can I find deals for business class flights from Syracuse to Key West?

    Yes. Cheapflights offers flight deals from Syracuse to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Syracuse to Key West?

    Currently, August is the cheapest month in which you can book a flight from Syracuse to Key West (average of $328). Flying from Syracuse to Key West in March is currently the most expensive (average of $491). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Syracuse to Key West

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Syracuse to Key West

Discover the top 4 airlines that operate flights from Syracuse to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$201Average$517FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$216Average$593FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$216Average$459FlexibilityNo cancel feeOn-time71%
DeltaCheapest$222Average$349FlexibilityNo cancel feeOn-timeN/A

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