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$110+ Cheap flights from Syracuse to Key West (SYR - EYW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/17. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — EYW
Dec 26 — Jan 21
Fri 12/26
Fri 1/2
1 adult, Economy
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Cheapflights Tip: The best prices from Syracuse Hancock Intl to Key West are usually found in August or June, booked 72 days in advance, depart on a Tuesday or Sunday and return on a Wednesday

Cheap flight deals from Syracuse to Key West

Discover tips and strategies to find the most affordable flight options for your journey from Syracuse (SYR) to Key West (EYW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 26, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$217
(Trip.com)

One-way from

$110
(American Airlines)

Popular in

April

Cheapest in

August

Average price

$414
Provider with most accurate pricing for Syracuse Hancock Intl-Key West flight deals.
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Provider most trusted by Cheapflights users for Syracuse Hancock Intl-Key West flights.
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From Syracuse Hancock Intl to Key West
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One-way flight from Syracuse Hancock Intl to Key West
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Highest demand for flights based on searches. 16% potential increase in price ($83 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($21 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Syracuse to Key West

Cheapest flights from Syracuse to Key West
Explore the most affordable flight options available from Syracuse to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 26, 2025.

This American Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/111:42 pmSYR - EYW
1 stop8h 03mAmerican Airlines
Mon 12/156:33 pmEYW - SYR
1 stop4h 58mAmerican Airlines
Deal found 11/24$265
This Kiwi.com deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/912:55 pmSYR - EYW
2 stops21h 12mMultiple Airlines
Sat 12/132:30 pmEYW - SYR
1 stop18h 55mMultiple Airlines
Deal found 11/23$297
This American Airlines deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/131:40 pmSYR - EYW
1 stop8h 10mAmerican Airlines
Fri 12/194:40 pmEYW - SYR
1 stop7h 41mAmerican Airlines
Deal found 11/25$304
This Delta deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/96:00 amSYR - EYW
1 stop5h 43mDelta
Sat 12/136:10 pmEYW - SYR
1 stop5h 23mDelta
Deal found 11/23$311
This Delta deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/135:30 amSYR - EYW
2 stops11h 45mDelta
Fri 12/193:02 pmEYW - SYR
2 stops8h 18mDelta
Deal found 11/24$314
This Kiwi.com deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2011:49 amSYR - EYW
1 stop20h 26mMultiple Airlines
Tue 12/2310:32 pmEYW - SYR
1 stop19h 08mMultiple Airlines
Deal found 11/24$317
This Kiwi.com deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/237:58 pmSYR - EYW
1 stop11h 09mMultiple Airlines
Tue 12/3010:32 pmEYW - SYR
1 stop19h 48mMultiple Airlines
Deal found 11/23$328

Cheapflights Fare Finder

 
Customize your flight search to find flights from Syracuse to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 26, 2025.
Use the filters below to find and compare flights from Syracuse to Key West that are best for you.

Fly from

Syracuse

Fly to

Key West

Route

Depart

Return

Price

SyracuseKey West

SYR - EYW

SYREYW

Syracuse Hancock Intl

Tue 1/27

6:00 am-11:25 am

1 stop5h 25m

Key West

Fri 1/30

6:06 pm-11:51 pm

1 stop5h 45m

$219

SyracuseKey West

SYR - EYW

SYREYW

Syracuse Hancock Intl

Mon 1/5

5:26 pm-10:44 pm

1 stop5h 18m

Key West

Fri 1/9

7:08 am-2:15 pm

1 stop7h 07m

$219

SyracuseKey West

SYR - EYW

SYREYW

Syracuse Hancock Intl

Tue 1/13

6:15 am-12:48 pm

1 stop6h 33m

Key West

Tue 1/27

2:45 pm-12:22 am

2 stops9h 37m

$224

SyracuseKey West

SYR - EYW

SYREYW

Syracuse Hancock Intl

Mon 1/5

6:15 am-12:48 pm

1 stop6h 33m

Key West

Fri 1/9

7:10 am-5:14 pm

2 stops10h 04m

$224

SyracuseKey West

SYR - EYW

SYREYW

Syracuse Hancock Intl

Sun 1/25

7:00 am-12:48 pm

1 stop5h 48m

$110

SyracuseKey West

SYR - EYW

SYREYW

Syracuse Hancock Intl

Wed 12/17

3:57 pm-9:46 pm

1 stop5h 49m

$110

SyracuseKey West

SYR - EYW

SYREYW

Syracuse Hancock Intl

Mon 1/26

6:15 am-12:48 pm

1 stop6h 33m

$110

SyracuseKey West

SYR - EYW

SYREYW

Syracuse Hancock Intl

Tue 2/17

1:37 pm-10:49 pm

2 stops9h 12m

$115

SyracuseKey West

SYR - EYW

SYREYW

Syracuse Hancock Intl

Wed 12/17

2:43 pm-1:30 pm

3 stops46h 47m

$249

SyracuseKey West

SYR - EYW

SYREYW

Syracuse Hancock Intl

Tue 2/17

12:10 pm-9:06 am

3 stops44h 56m

$309

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/26

Compare providers for flights from Syracuse to Key West

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Syracuse to Key West in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Syracuse-Key West flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Syracuse-Key West flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Syracuse-Key West flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Syracuse-Key West flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Syracuse-Key West flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Syracuse to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from Syracuse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to Key West

How far ahead should I book a flight from Syracuse to Key West?

Use this chart to determine the optimal time to book a round-trip flight from Syracuse to Key West. Price data was last updated on November 21, 2025.

The best time to book flights from Syracuse to Key West is 35 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Syracuse to Key West?

Currently, May is the cheapest month in which you can book a flight from Syracuse to Key West (average of $199). Flying from Syracuse to Key West in November is currently the most expensive (average of $278). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Syracuse to Key West?

Reviews of airlines servicing Key West

Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated November 26, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Syracuse to Key West by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,999 reviews

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

7.9

Boarding

8.1

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
7.9
Good
7,999 reviews
Delta
7.9
Good
7,999 reviews

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

7.9

Boarding

8.1

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
United Airlines
7.4
Good
9,046 reviews
Delta
7.9
Good
7,999 reviews

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

7.9

Boarding

8.1

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
American Airlines
7.2
Good
11,038 reviews
Delta
7.9
Good
7,999 reviews

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

7.9

Boarding

8.1

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
JetBlue
7.2
Good
2,905 reviews
Delta
7.9
Good
7,999 reviews

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

7.9

Boarding

8.1

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Syracuse to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Syracuse to Key West?

    For as low as $219, Delta can have you in Key West from Syracuse in 5h 18m. There are 1321 mi between Syracuse and Key West. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Syracuse to Key West round-trip?

    Flying on American Airlines is currently your cheapest option to Key West, with prices starting at $217. Additional round-trip tickets that might be worth considering are offered by Delta and United Airlines, with the lowest prices starting at $218 and $343, respectively. American Airlines is currently priced 49% below the average price you’ll pay for this route.

  • Can I find deals for flights from Syracuse to Key West that include hotel bookings?

    Yes. In addition to deals on Syracuse to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Syracuse to Key West?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to Key West.

  • Can I find deals for business class flights from Syracuse to Key West?

    Yes. Cheapflights offers flight deals from Syracuse to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Syracuse to Key West?

    Currently, May is the cheapest month in which you can book a flight from Syracuse to Key West (average of $199). Flying from Syracuse to Key West in November is currently the most expensive (average of $278). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Syracuse to Key West

Discover the top 4 airlines that operate flights from Syracuse to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$216Average$436FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$217Average$446FlexibilityNo cancel feeOn-time71%
DeltaCheapest$218Average$348FlexibilityNo cancel feeOn-timeN/A
JetBlueCheapest$382Average$474FlexibilityNo cancel feeOn-time62%

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