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$286+ Cheap flights from South Dakota to Key West (EYW)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/25. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — EYW
Dec 6 — Dec 131
Sat 12/6
Sat 12/13
1 adult, Economy
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Find flight deals from South Dakota to Key West

Cheapest flights from South Dakota to Key West
Explore the most affordable flight options available from South Dakota to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2025.

This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/85:30 amFSD - EYW
1 stop4h 57mDelta
Wed 11/126:18 pmEYW - FSD
1 stop5h 51mDelta
Deal found 11/5$456
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/78:00 amFSD - EYW
1 stop6h 19mUnited Airlines
Wed 11/124:00 pmEYW - FSD
1 stop6h 46mUnited Airlines
Deal found 11/4$519
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/268:26 pmFSD - EYW
2 stops35h 51mMultiple Airlines
Sun 11/303:30 pmEYW - FSD
1 stop19h 33mMultiple Airlines
Deal found 11/4$530
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/88:00 amFSD - EYW
1 stop6h 19mUnited Airlines
Wed 11/124:00 pmEYW - FSD
1 stop6h 46mUnited Airlines
Deal found 11/4$579
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/265:54 pmFSD - EYW
1 stop20h 51mAllegiant Air
Sun 11/303:30 pmEYW - FSD
1 stop19h 33mAllegiant Air
Deal found 11/4$602
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/710:15 amFSD - EYW
1 stop21h 46mMultiple Airlines
Wed 11/1210:47 amEYW - FSD
2 stops27h 41mMultiple Airlines
Deal found 11/4$625
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/42:02 pmFSD - EYW
2 stops8h 05mAmerican Airlines
Mon 12/812:00 pmEYW - FSD
2 stops12h 59mAmerican Airlines
Deal found 11/5$716

Cheap flight deals from South Dakota to Key West

Keep the following information in mind while searching for South Dakota to Key West flight deals. Data was last updated November 6, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$286
(American Airlines)

Popular in

April

Cheapest in

July

Average price

$504
Provider with most accurate pricing for Sioux Falls Joe Foss Field-Key West flight deals.
Search Deals
Provider most trusted by Cheapflights users for Sioux Falls Joe Foss Field-Key West flights.
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From South Dakota to Key West
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($77 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Dakota to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from South Dakota to Key West that are best for you.

Fly from

South Dakota

Fly to

Key West

Route

Depart

Return

Price

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Wed 2/25

1:23 pm-10:59 pm

2 stops8h 36m

Key West

Wed 3/4

2:40 pm-9:39 pm

1 stop7h 59m

$286

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Fri 1/9

12:26 pm-9:47 pm

2 stops8h 21m

Key West

Fri 1/16

1:05 pm-9:30 pm

1 stop9h 25m

$294

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Tue 3/24

6:56 am-4:05 pm

1 stop8h 09m

Key West

Wed 4/1

3:48 pm-8:55 pm

1 stop6h 07m

$311

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Fri 1/9

7:30 am-3:17 pm

1 stop6h 47m

Key West

Fri 1/16

4:15 pm-9:50 pm

1 stop6h 35m

$398

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Mon 1/26

12:26 pm-11:56 pm

2 stops10h 30m

Key West

Mon 2/2

1:05 pm-9:30 pm

1 stop9h 25m

$411

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Thu 1/29

12:26 pm-9:47 pm

2 stops8h 21m

Key West

Thu 2/5

6:06 am-5:45 pm

2 stops12h 39m

$416

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Thu 1/29

6:02 pm-4:51 pm

2 stops21h 49m

Key West

Thu 2/5

10:27 pm-6:36 pm

1 stop21h 09m

$439

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/4

Best time to book a flight from South Dakota to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from South Dakota with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Dakota to Key West

What is the cheapest month to book a flight from South Dakota to Key West?

Currently, October is the cheapest month in which you can book a flight from South Dakota to Key West (average of $295). Flying from South Dakota to Key West in April is currently the most expensive (average of $543). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from South Dakota to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Key West from South Dakota?

    Most people fly into Key West (EYW) if they book a flight to Key West from South Dakota. Key West is conveniently located just 2.6 mi from Key West’s city center.

  • How long is the flight from South Dakota to Key West?

    A quick flight from South Dakota to Key West can take about 8h 36m. American Airlines provides one of the quickest options available for as low as $286. South Dakota and Key West are separated by a distance of 1563 mi.

  • Can I find deals for flights from South Dakota to Key West that include hotel bookings?

    Yes. In addition to deals on South Dakota to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Dakota to Key West?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Dakota to Key West.

  • Can I find deals for business class flights from South Dakota to Key West?

    Yes. Cheapflights offers flight deals from South Dakota to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Dakota to Key West?

    Currently, October is the cheapest month in which you can book a flight from South Dakota to Key West (average of $295). Flying from South Dakota to Key West in April is currently the most expensive (average of $543). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from South Dakota to Key West

Discover the top 3 airlines that operate flights from South Dakota to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$288Average$530FlexibilityNo cancel feeOn-time71%
DeltaCheapest$310Average$593FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$378Average$661FlexibilityNo cancel feeOn-time69%

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