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Key West

$293+ Cheap flights from South Dakota to Key West (EYW)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/8. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — EYW
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from South Dakota to Key West

Keep the following information in mind while searching for South Dakota to Key West flight deals. Data was last updated September 16, 2025.

Round-trip from

$293
(American Airlines)

Popular in

April

Cheapest in

July

Average price

$343
From South Dakota to Key West
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($90 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals

Find flight deals from South Dakota to Key West

Cheapest flights from South Dakota to Key West
Explore the most affordable flight options available from South Dakota to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/810:59 amFSD - EYW
2 stops9h 50mAmerican Airlines
Wed 11/121:23 pmEYW - FSD
2 stops10h 04mAmerican Airlines
Deal found 9/14$293
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/288:00 amFSD - EYW
1 stop6h 19mUnited Airlines
Sat 11/14:00 pmEYW - FSD
1 stop6h 46mUnited Airlines
Deal found 9/15$373
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/285:30 amFSD - EYW
1 stop4h 57mDelta
Sat 11/17:40 amEYW - FSD
2 stops9h 04mDelta
Deal found 9/15$376
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/296:49 amFSD - EYW
1 stop8h 29mAmerican Airlines
Sun 11/21:23 pmEYW - FSD
1 stop6h 22mAmerican Airlines
Deal found 9/14$383
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/286:49 amFSD - EYW
1 stop8h 29mAmerican Airlines
Sun 11/21:23 pmEYW - FSD
1 stop6h 22mAmerican Airlines
Deal found 9/15$423
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/93:05 pmABR - EYW
2 stops27h 58mDelta
Sat 12/137:40 amEYW - ABR
2 stops7h 49mDelta
Deal found 9/15$637

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Dakota to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from South Dakota to Key West that are best for you.

Fly from

South Dakota

Fly to

Key West

Route

Depart

Return

Price

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Sat 11/8

10:59 am-9:49 pm

2 stops9h 50m

Key West

Wed 11/12

1:23 pm-10:27 pm

2 stops10h 04m

$293

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Tue 10/28

8:00 am-3:19 pm

1 stop6h 19m

Key West

Sat 11/1

4:00 pm-9:46 pm

1 stop6h 46m

$373

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Tue 10/28

5:30 am-11:27 am

1 stop4h 57m

Key West

Sat 11/1

7:40 am-3:44 pm

2 stops9h 04m

$376

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Wed 10/29

6:49 am-7:22 pm

2 stops11h 33m

Key West

Sun 11/2

1:23 pm-6:45 pm

1 stop6h 22m

$388

AberdeenKey West

ABR - EYW

ABREYW

Aberdeen

Tue 12/9

3:05 pm-8:03 pm

2 stops27h 58m

Key West

Sat 12/13

7:40 am-2:29 pm

2 stops7h 49m

$637

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Sat 11/15

1:47 pm-2:04 pm

3 stops23h 17m

$320

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Sat 11/15

6:30 am-4:16 pm

1 stop8h 46m

$337

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Sat 11/15

8:01 am-7:53 pm

2 stops10h 52m

$342

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Wed 10/1

8:54 pm-9:02 am

3 stops59h 08m

$402

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Best time to book a flight from South Dakota to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from South Dakota with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Dakota to Key West

What is the cheapest month to book a flight from South Dakota to Key West?

Currently, August is the cheapest month in which you can book a flight from South Dakota to Key West (average of $328). Flying from South Dakota to Key West in March is currently the most expensive (average of $491). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from South Dakota to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Key West from South Dakota?

    Most people fly into Key West (EYW) if they book a flight to Key West from South Dakota. Key West is conveniently located just 2.6 mi from Key West’s city center.

  • How long is the flight from South Dakota to Key West?

    A quick flight from South Dakota to Key West can take about 6h 19m. American Airlines provides one of the quickest options available for as low as $373. South Dakota and Key West are separated by a distance of 1563 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from South Dakota to Key West one-way?

    $320 is the cheapest one-way deal found within the past few days, from United Airlines. You may also be able to find cheap deals on American Airlines and Delta, with prices starting from $337 and $342, respectively.

  • Can I find deals for flights from South Dakota to Key West that include hotel bookings?

    Yes. In addition to deals on South Dakota to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Dakota to Key West?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Dakota to Key West.

  • Can I find deals for business class flights from South Dakota to Key West?

    Yes. Cheapflights offers flight deals from South Dakota to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Dakota to Key West?

    Currently, August is the cheapest month in which you can book a flight from South Dakota to Key West (average of $328). Flying from South Dakota to Key West in March is currently the most expensive (average of $491). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from South Dakota to Key West

Discover the top 3 airlines that operate flights from South Dakota to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$288Average$528FlexibilityNo cancel feeOn-time71%
DeltaCheapest$310Average$593FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$378Average$644FlexibilityNo cancel feeOn-time69%

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