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Key West

$589+ Cheap flights from South America to Key West (EYW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/22. Fares are subject to change and may not be available on all flights or dates of travel.
BOG — EYW
Aug 25 — Sep 11
Mon 8/25
Mon 9/1
1 adult, Economy
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Cheap flight deals from South America to Key West

Keep the following information in mind while searching for South America to Key West flight deals. Data was last updated August 20, 2025.

Round-trip from

$741
(American Airlines)

One-way from

$589
(Kiwi.com)
From South America to Key West
Search Deals
One-way flight from South America to Key West
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Find flight deals from South America to Key West

Cheapest flights from South America to Key West
Explore the most affordable flight options available from South America to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 20, 2025.

This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/266:00 amMDE - EYW
1 stop27h 54mAmerican Airlines
Tue 9/3011:25 amEYW - MDE
1 stop26h 25mAmerican Airlines
Deal found 8/18$741
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/267:17 amMDE - EYW
2 stops26h 38mDelta
Tue 9/306:10 pmEYW - MDE
2 stops48h 45mDelta
Deal found 8/18$755
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/188:45 pmEZE - EYW
1 stop15h 08mAmerican Airlines
Thu 8/287:40 pmEYW - EZE
1 stop10h 45mAmerican Airlines
Deal found 8/18$1,414
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/38:40 pmEZE - EYW
1 stop15h 14mAmerican Airlines
Tue 10/711:22 amEYW - EZE
1 stop19h 03mAmerican Airlines
Deal found 8/18$1,720
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/291:45 amASU - EYW
2 stops38h 34mUnited Airlines
Mon 11/34:00 pmEYW - ASU
2 stops30h 11mUnited Airlines
Deal found 8/17$3,723

Cheapflights Fare Finder

 
Customize your flight search to find flights from South America to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
Use the filters below to find and compare flights from South America to Key West that are best for you.

Fly from

South America

Fly to

Key West

Route

Depart

Return

Price

MedellínKey West

MDE - EYW

MDEEYW

Medellín Jose Maria Cordova Intl

Fri 9/26

6:00 am-10:54 am

1 stop27h 54m

Key West

Tue 9/30

11:25 am-12:50 pm

1 stop26h 25m

$741

MedellínKey West

MDE - EYW

MDEEYW

Medellín Jose Maria Cordova Intl

Fri 9/26

7:17 am-10:55 am

2 stops26h 38m

Key West

Tue 9/30

6:10 pm-5:55 pm

2 stops48h 45m

$755

Buenos AiresKey West

EZE - EYW

EZEEYW

Buenos Aires Ministro Pistarini

Fri 10/3

8:40 pm-10:54 am

1 stop15h 14m

Key West

Tue 10/7

11:22 am-7:25 am

1 stop19h 03m

$1,720

AsuncionKey West

ASU - EYW

ASUEYW

Asuncion Silvio Pettirossi

Wed 10/29

1:45 am-3:19 pm

2 stops38h 34m

Key West

Mon 11/3

4:00 pm-12:11 am

2 stops30h 11m

$3,723

Buenos AiresKey West

EZE - EYW

EZEEYW

Buenos Aires Ministro Pistarini

Mon 12/22

9:15 pm-2:25 pm

2 stops19h 10m

$589

Buenos AiresKey West

EZE - EYW

EZEEYW

Buenos Aires Ministro Pistarini

Mon 12/22

11:59 pm-6:39 pm

1 stop20h 40m

$731

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/19

Best time to book a flight from South America to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from South America with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South America to Key West
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from South America to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Key West from South America?

    Key West (EYW), located 2.6 mi from the city center, is the airport you fly into when you book flights from South America to Key West.

  • How long is the flight from South America to Key West?

    Airlines like American Airlines, Delta, and United Airlines fly from South America to Key West in about 26h 38m. The time it takes to get you to your destination can typically vary by up to 11h 56m. The distance from South America to Key West is about 1337 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from South America to Key West?

    The most popular flight routes from South America to Key West are Buenos Aires Ministro Pistarini - Key West, Medellín Jose Maria Cordova Intl - Key West and Asuncion Silvio Pettirossi - Key West.

  • Can I find deals for flights from South America to Key West that include hotel bookings?

    Yes. In addition to deals on South America to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South America to Key West?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South America to Key West.

  • Can I find deals for business class flights from South America to Key West?

    Yes. Cheapflights offers flight deals from South America to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South America to Key West?

    Currently, August is the cheapest month in which you can book a flight from South America to Key West (average of $328). Flying from South America to Key West in March is currently the most expensive (average of $492). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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