How long is the flight from Roanoke to Key West?

Airlines like American Airlines and Delta fly from Roanoke to Key West in about 4h 58m. The time it takes to get you to your destination can typically vary by up to 20m. Airlines will cover a distance of 888 mi. Both multi-stop and nonstop flights can be found to your destination and back.

What are the cheapest airlines flying from Roanoke to Key West round-trip?

American Airlines, at $248, was found to be the cheapest airline from Roanoke to Key West. An alternate airline flying to your destination would be Delta. American Airlines is currently priced 43% below the average price you’ll pay for this route.

In terms of precipitation, rainfall in Key West ranges from 1.5 - 6.7 inches per month. September is typically the wettest month, when rainfall can reach 6.7 in. February is typically the driest time to visit Key West when rainfall is around 1.5 in.

If weather is an important factor for your trip to Key West, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 69.8 F).

What is the cheapest time of day to fly from ROA to EYW?

When flying from Roanoke to Key West, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Most accurate provider : When it comes to deals on Roanoke-Key West flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Roanoke-Key West flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Roanoke-Key West flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Roanoke-Key West flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Roanoke-Key West flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Roanoke to Key West that include hotel bookings?

Yes. In addition to deals on Roanoke to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Roanoke to Key West?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to Key West.

Can I find deals for business class flights from Roanoke to Key West?

Yes. Cheapflights offers flight deals from Roanoke to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$129+ Flights from Roanoke to Key West

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Cheap flight deals from Roanoke to Key West

Cheapest flights from Roanoke to Key West
Explore the most affordable flight options available from Roanoke to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 7, 2025.

Fri 12/55:03 pmROA - EYW

1 stop5h 15mAmerican Airlines

Mon 12/84:04 pmEYW - ROA

1 stop6h 52mAmerican Airlines

Deal found 12/5

$369

Fri 12/196:15 amROA - EYW

1 stop5h 26mUnited Airlines

Fri 12/265:10 pmEYW - ROA

1 stop6h 20mUnited Airlines

Deal found 12/6

$379

Fri 12/198:14 amROA - EYW

1 stop5h 33mAmerican Airlines

Fri 12/2612:04 pmEYW - ROA

1 stop8h 23mAmerican Airlines

Deal found 12/5

$386

Sat 12/209:29 pmROA - EYW

1 stop17h 05mAllegiant Air

Wed 12/248:45 pmEYW - ROA

2 stops41h 57mAllegiant Air

Deal found 12/5

$408

Sat 12/202:55 pmROA - EYW

1 stop25h 34mUnited Airlines

Wed 12/241:25 pmEYW - ROA

1 stop5h 26mUnited Airlines

Deal found 12/5

$533

Best flights from Roanoke to Key West
Discover carefully curated flight deals from Roanoke to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 7, 2025.

Fri 2/65:14 pmROA - EYW

1 stop4h 33mAmerican Airlines

Tue 2/106:06 amEYW - ROA

2 stops10h 04mAmerican Airlines

Deal found 12/5

$254

Tue 4/146:00 amROA - EYW

1 stop4h 58mDelta

Wed 4/226:00 pmEYW - ROA

1 stop5h 49mDelta

Deal found 12/5

$264

Fri 1/233:30 pmROA - EYW

2 stops8h 26mAmerican Airlines

Mon 1/266:43 pmEYW - ROA

1 stop4h 10mAmerican Airlines

Deal found 12/5

$254

Sat 4/256:00 amROA - EYW

1 stop4h 58mDelta

Tue 4/286:00 pmEYW - ROA

1 stop5h 49mDelta

Deal found 12/5

$304

Thu 1/225:14 pmROA - EYW

1 stop4h 33mAmerican Airlines

Mon 1/266:43 pmEYW - ROA

1 stop4h 10mAmerican Airlines

Deal found 12/7

$294

Sat 4/183:25 pmROA - EYW

1 stop4h 19mDelta

Wed 4/226:00 pmEYW - ROA

1 stop5h 49mDelta

Deal found 12/5

$319

Sat 4/183:25 pmROA - EYW

1 stop4h 19mDelta

Tue 4/216:00 pmEYW - ROA

1 stop5h 49mDelta

Deal found 12/5

$319

Sat 4/258:16 amROA - EYW

2 stops8h 05mAmerican Airlines

Tue 4/285:22 pmEYW - ROA

1 stop6h 20mAmerican Airlines

Deal found 12/5

$324

Wed 4/153:25 pmROA - EYW

1 stop4h 19mDelta

Tue 4/216:00 pmEYW - ROA

1 stop5h 49mDelta

Deal found 12/5

$343

Last-minute flights from Roanoke to Key West
Discover last-minute flight deals from Roanoke to Key West. Data last updated December 7, 2025 and is based on user searches.

Fri 12/55:03 pmROA - EYW

1 stop5h 15mAmerican Airlines

Mon 12/84:04 pmEYW - ROA

1 stop6h 52mAmerican Airlines

Deal found 12/5

$369

Fri 12/196:15 amROA - EYW

1 stop5h 26mUnited Airlines

Fri 12/265:10 pmEYW - ROA

1 stop6h 20mUnited Airlines

Deal found 12/6

$379

Fri 12/198:14 amROA - EYW

1 stop5h 33mAmerican Airlines

Fri 12/2612:04 pmEYW - ROA

1 stop8h 23mAmerican Airlines

Deal found 12/5

$386

Sat 12/209:29 pmROA - EYW

1 stop17h 05mAllegiant Air

Wed 12/248:45 pmEYW - ROA

2 stops41h 57mAllegiant Air

Deal found 12/5

$408

Fri 1/2312:43 pmROA - EYW

1 stop5h 18mAmerican Airlines

Mon 1/266:43 pmEYW - ROA

1 stop4h 10mAmerican Airlines

Deal found 12/5

$249

Sat 1/2410:15 amROA - EYW

1 stop6h 07mUnited Airlines

Wed 1/286:05 pmEYW - ROA

1 stop20h 04mUnited Airlines

Deal found 12/4

$428

Fri 1/3012:43 pmROA - EYW

1 stop5h 18mAmerican Airlines

Mon 2/26:06 amEYW - ROA

2 stops8h 59mAmerican Airlines

Deal found 12/6

$344

One-way flights from Roanoke to Key West
Search for one-way flight options from Roanoke to Key West. Find affordable one-way fares based on user searches. Data last updated December 7, 2025.

Tue 12/239:40 pmROA - EYW

1 stop16h 59mAllegiant Air

Deal found 12/5

$129

Sat 12/209:29 pmROA - EYW

1 stop10h 46mMultiple Airlines

Deal found 12/5

$142

Sun 12/214:01 pmROA - EYW

1 stop5h 36mAllegiant Air

Deal found 12/5

$175

Mon 12/226:41 pmROA - EYW

1 stop19h 44mAllegiant Air

Deal found 12/5

$181

Thu 12/184:01 pmROA - EYW

1 stop5h 41mAllegiant Air

Deal found 12/5

$201

Tue 12/239:40 pmROA - EYW

3 stops34h 35mMultiple Airlines

Deal found 12/5

$220

Mon 12/229:31 pmROA - EYW

3 stops39h 59mMultiple Airlines

Deal found 12/5

$224

Fri 12/199:31 pmROA - EYW

2 stops37h 09mAllegiant Air

Deal found 12/5

$225

Find flight deals from Roanoke to Key West

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$249 (American Airlines)
One-way from	$129 (Kiwi.com)
Popular in	April
Cheapest in	February
Average price	$318

Provider with most accurate pricing for Roanoke-Key West flight deals.

Search Deals

Provider most trusted by Cheapflights users for Roanoke-Key West flights.

Search Deals

From Roanoke to Key West

Search Deals

One-way flight from Roanoke to Key West

Search Deals

Highest demand for flights based on searches. 17% potential increase in price ($89 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($12 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Fly from

Fly to

Route

Depart

Return

Price

RoanokeKey West

ROA - EYW

ROAEYW

Roanoke

Fri 2/6

5:14 pm-9:47 pm

1 stop4h 33m

Key West

Tue 2/10

6:06 am-4:10 pm

2 stops10h 04m

$254

RoanokeKey West

ROA - EYW

ROAEYW

Roanoke

Fri 1/23

3:30 pm-11:56 pm

2 stops8h 26m

Key West

Mon 1/26

6:43 pm-10:53 pm

1 stop4h 10m

$254

RoanokeKey West

ROA - EYW

ROAEYW

Roanoke

Tue 4/14

6:00 am-10:58 am

1 stop4h 58m

Key West

Wed 4/22

6:00 pm-11:49 pm

1 stop5h 49m

$264

RoanokeKey West

ROA - EYW

ROAEYW

Roanoke

Thu 1/22

5:14 pm-9:47 pm

1 stop4h 33m

Key West

Mon 1/26

6:43 pm-10:53 pm

1 stop4h 10m

$294

RoanokeKey West

ROA - EYW

ROAEYW

Roanoke

Sat 4/25

6:00 am-10:58 am

1 stop4h 58m

Key West

Tue 4/28

6:00 pm-11:49 pm

1 stop5h 49m

$304

RoanokeKey West

ROA - EYW

ROAEYW

Roanoke

Sat 4/18

3:25 pm-7:44 pm

1 stop4h 19m

Key West

Wed 4/22

6:00 pm-11:49 pm

1 stop5h 49m

$319

RoanokeKey West

ROA - EYW

ROAEYW

Roanoke

Sat 4/18

3:25 pm-7:44 pm

1 stop4h 19m

Key West

Tue 4/21

6:00 pm-11:49 pm

1 stop5h 49m

$319

RoanokeKey West

ROA - EYW

ROAEYW

Roanoke

Sat 4/25

8:16 am-4:21 pm

2 stops8h 05m

Key West

Tue 4/28

5:22 pm-11:42 pm

1 stop6h 20m

$324

RoanokeKey West

ROA - EYW

ROAEYW

Roanoke

Wed 4/15

3:25 pm-7:44 pm

1 stop4h 19m

Key West

Tue 4/21

6:00 pm-11:49 pm

1 stop5h 49m

$343

RoanokeKey West

ROA - EYW

ROAEYW

Roanoke

Tue 12/23

9:40 pm-2:39 pm

1 stop16h 59m

$129

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/5

Showing 1-10 of 18 results

Compare providers for flights from Roanoke to Key West

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Roanoke to Key West in December.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Roanoke-Key West flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Roanoke-Key West flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Roanoke-Key West flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Roanoke-Key West flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Roanoke-Key West flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Roanoke to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from Roanoke with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to Key West

What is the cheapest month to book a flight from Roanoke to Key West?

Currently, April is the cheapest month in which you can book a flight from Roanoke to Key West (average of $203). Flying from Roanoke to Key West in November is currently the most expensive (average of $413). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Key West

Read through reviews of airlines operating flights from Roanoke to Key West, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Delta

7.9

Good

8,013 reviews

Reviews

1 / 20

2.0

Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Delta

7.9

Good

8,013 reviews

Delta

7.9

Good

8,013 reviews

Reviews

1 / 20

2.0

Mediocre

Joseph,Aug 2023

MSP - MCO

American Airlines

7.2

Good

11,046 reviews

Delta

7.9

Good

8,013 reviews

Reviews

1 / 20

2.0

Mediocre

Joseph,Aug 2023

MSP - MCO

Related info for your journey

How long is the flight from Roanoke to Key West?
Airlines like American Airlines and Delta fly from Roanoke to Key West in about 4h 58m. The time it takes to get you to your destination can typically vary by up to 20m. Airlines will cover a distance of 888 mi. Both multi-stop and nonstop flights can be found to your destination and back.
What are the cheapest airlines flying from Roanoke to Key West round-trip?
American Airlines, at $248, was found to be the cheapest airline from Roanoke to Key West. An alternate airline flying to your destination would be Delta. American Airlines is currently priced 43% below the average price you’ll pay for this route.
Can I find deals for flights from Roanoke to Key West that include hotel bookings?
Yes. In addition to deals on Roanoke to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Roanoke to Key West?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to Key West.
Can I find deals for business class flights from Roanoke to Key West?
Yes. Cheapflights offers flight deals from Roanoke to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Roanoke to Key West?
Currently, April is the cheapest month in which you can book a flight from Roanoke to Key West (average of $203). Flying from Roanoke to Key West in November is currently the most expensive (average of $413). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Other flights to Key West

Top 2 airlines flying from Roanoke to Key West

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$248	Average$378	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$248	Average$473	FlexibilityNo cancel fee	On-time71%

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$129+ Cheap flights from Roanoke to Key West (ROA - EYW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/23. Fares are subject to change and may not be available on all flights or dates of travel.

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Cheap flight deals from Roanoke to Key West

Cheapest flights from Roanoke to Key WestExplore the most affordable flight options available from Roanoke to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 7, 2025.

Explore the most affordable flight options available from Roanoke to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 7, 2025.

Find flight deals from Roanoke to Key West

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Roanoke to Key West that are best for you.

Compare providers for flights from Roanoke to Key West

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Roanoke to Key West in December.

Best time to book a flight from Roanoke to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from Roanoke with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to Key West

What is the cheapest month to book a flight from Roanoke to Key West?

Reviews of airlines servicing Key West

Read through reviews of airlines operating flights from Roanoke to Key West, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Roanoke to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Roanoke to Key West?

What are the cheapest airlines flying from Roanoke to Key West round-trip?

Can I find deals for flights from Roanoke to Key West that include hotel bookings?

How can I find direct flights from Roanoke to Key West?

Can I find deals for business class flights from Roanoke to Key West?

What is the cheapest month to book a flight from Roanoke to Key West?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Roanoke to Key West

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Roanoke to Key West

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Cheapest flights from Roanoke to Key West
Explore the most affordable flight options available from Roanoke to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 7, 2025.