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$129+ Cheap flights from Roanoke to Key West (ROA - EYW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/19. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — EYW
Feb 11 — Feb 181
Wed 2/11
Wed 2/18
1 adult, Economy
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Cheap flight deals from Roanoke to Key West

Discover tips and strategies to find the most affordable flight options for your journey from Roanoke (ROA) to Key West (EYW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 12, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$283
(American Airlines)

One-way from

$129
(Kiwi.com)

Popular in

March

Cheapest in

December

Average price

$326
Provider with most accurate pricing for Roanoke-Key West flight deals.
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Provider most trusted by Cheapflights users for Roanoke-Key West flights.
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From Roanoke to Key West
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One-way flight from Roanoke to Key West
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Highest demand for flights based on searches. 19% potential increase in price ($106 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($22 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Find flight deals from Roanoke to Key West

Cheapest flights from Roanoke to Key West
Explore the most affordable flight options available from Roanoke to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 12, 2026.

This American Airlines deal was found by Cheapflights users on 1/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/182:50 pm
ROA
-
EYW
1 stop7h 32m
American Airlines
Wed 2/253:20 pm
EYW
-
ROA
1 stop6h 30m
American Airlines
Deal found 1/11$283
This American Airlines deal was found by Cheapflights users on 1/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/35:14 pm
ROA
-
EYW
1 stop4h 33m
American Airlines
Tue 2/107:08 am
EYW
-
ROA
1 stop5h 01m
American Airlines
Deal found 1/11$286
This American Airlines deal was found by Cheapflights users on 1/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/25:14 pm
ROA
-
EYW
1 stop4h 33m
American Airlines
Thu 2/124:40 pm
EYW
-
ROA
1 stop7h 05m
American Airlines
Deal found 1/11$289
This Delta deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/63:11 pm
ROA
-
EYW
1 stop4h 29m
Delta
Thu 5/146:00 pm
EYW
-
ROA
1 stop5h 49m
Delta
Deal found 1/12$306
This American Airlines deal was found by Cheapflights users on 1/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/188:15 am
ROA
-
EYW
2 stops10h 57m
American Airlines
Wed 3/254:40 pm
EYW
-
ROA
1 stop7h 05m
American Airlines
Deal found 1/10$341
This American Airlines deal was found by Cheapflights users on 1/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/233:30 pm
ROA
-
EYW
1 stop6h 17m
American Airlines
Fri 1/307:08 am
EYW
-
ROA
1 stop5h 01m
American Airlines
Deal found 1/11$349

Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 12, 2026.
Use the filters below to find and compare flights from Roanoke to Key West that are best for you.

Fly from

Roanoke

Fly to

Key West

Route

Depart

Return

Price

RoanokeKey West

ROA - EYW

ROAEYW

Roanoke

Wed 2/18

2:50 pm-10:22 pm

1 stop7h 32m

Key West

Wed 2/25

3:20 pm-9:50 pm

1 stop6h 30m

$283

RoanokeKey West

ROA - EYW

ROAEYW

Roanoke

Tue 3/3

8:15 am-2:05 pm

1 stop5h 50m

Key West

Tue 3/10

8:04 am-8:30 pm

2 stops12h 26m

$288

RoanokeKey West

ROA - EYW

ROAEYW

Roanoke

Mon 2/2

5:14 pm-9:47 pm

1 stop4h 33m

Key West

Thu 2/12

4:40 pm-11:45 pm

1 stop7h 05m

$289

RoanokeKey West

ROA - EYW

ROAEYW

Roanoke

Tue 2/3

3:30 pm-11:56 pm

2 stops8h 26m

Key West

Tue 2/10

6:06 am-4:10 pm

2 stops10h 04m

$297

RoanokeKey West

ROA - EYW

ROAEYW

Roanoke

Tue 5/5

6:00 am-10:52 am

1 stop4h 52m

Key West

Tue 5/12

6:00 pm-11:49 pm

1 stop5h 49m

$341

RoanokeKey West

ROA - EYW

ROAEYW

Roanoke

Wed 3/18

8:15 am-7:12 pm

2 stops10h 57m

Key West

Wed 3/25

3:56 pm-11:45 pm

2 stops7h 49m

$347

RoanokeKey West

ROA - EYW

ROAEYW

Roanoke

Tue 3/3

3:25 pm-7:42 pm

1 stop4h 17m

Key West

Tue 3/10

6:25 pm-12:04 am

1 stop5h 39m

$358

RoanokeKey West

ROA - EYW

ROAEYW

Roanoke

Tue 2/3

6:00 am-11:25 am

1 stop5h 25m

Key West

Mon 2/9

6:06 pm-12:04 am

1 stop5h 58m

$359

RoanokeKey West

ROA - EYW

ROAEYW

Roanoke

Wed 3/18

6:00 am-10:48 am

1 stop4h 48m

Key West

Wed 3/25

6:25 pm-12:04 am

1 stop5h 39m

$381

RoanokeKey West

ROA - EYW

ROAEYW

Roanoke

Wed 1/28

12:43 pm-6:01 pm

1 stop5h 18m

Key West

Sat 1/31

7:15 am-1:31 pm

1 stop6h 16m

$387

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/9

Showing 1-10 of 20 results
1
2

Compare providers for flights from Roanoke to Key West

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Roanoke to Key West in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Roanoke-Key West flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Roanoke-Key West flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Roanoke-Key West flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Roanoke-Key West flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Roanoke-Key West flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Roanoke to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to Key West

What is the cheapest month to book a flight from Roanoke to Key West?

Currently, April is the cheapest month in which you can book a flight from Roanoke to Key West (average of $198). Flying from Roanoke to Key West in November is currently the most expensive (average of $413). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Key West

Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated January 12, 2026.
Read through reviews of airlines operating flights from Roanoke to Key West, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,039 reviews

Food

7.2

Entertainment

7.8

Overall

7.9

Comfort

7.9

Boarding

8.1

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Delta
7.9
Good
8,039 reviews
Delta
7.9
Good
8,039 reviews

Food

7.2

Entertainment

7.8

Overall

7.9

Comfort

7.9

Boarding

8.1

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
American Airlines
7.2
Good
11,114 reviews
Delta
7.9
Good
8,039 reviews

Food

7.2

Entertainment

7.8

Overall

7.9

Comfort

7.9

Boarding

8.1

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Related info for your journey

Find useful and relevant information for your journey from Roanoke to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Roanoke to Key West?

    Airlines like American Airlines fly from Roanoke to Key West in about 7h 32m. The time it takes to get you to your destination can typically vary by up to . Airlines will cover a distance of 888 mi.

  • What are the cheapest airlines flying from Roanoke to Key West round-trip?

    American Airlines, at $248, was found to be the cheapest airline from Roanoke to Key West. An alternate airline flying to your destination would be Delta. American Airlines is currently priced 44% below the average price you’ll pay for this route.

  • Can I find deals for flights from Roanoke to Key West that include hotel bookings?

    Yes. In addition to deals on Roanoke to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to Key West?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to Key West.

  • Can I find deals for business class flights from Roanoke to Key West?

    Yes. Cheapflights offers flight deals from Roanoke to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Roanoke to Key West?

    Currently, April is the cheapest month in which you can book a flight from Roanoke to Key West (average of $198). Flying from Roanoke to Key West in November is currently the most expensive (average of $413). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from Roanoke to Key West

Discover the top 2 airlines that operate flights from Roanoke to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 12, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$248Average$373FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$464FlexibilityNo cancel feeOn-time71%

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