$273+ Cheap flights from Roanoke to Key West (ROA - EYW)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/19. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — EYW
Nov 19 — Nov 261
Round-trip
1 adult, Economy
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Find cheap flights from Roanoke to Key West with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Roanoke to Key West
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Best
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One-way
Cheapest flights from Roanoke to Key WestExplore the most affordable flight options available from Roanoke to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 20, 2026.
Explore the most affordable flight options available from Roanoke to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 20, 2026.
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/302:14 pm -
1 stop4h 35m
Tue 11/35:50 pm -
1 stop5h 01m
Deal found 10/15![American Airlines logo]()
$389
This Kiwi.com deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/154:12 pm -
1 stop21h 49m
Sun 11/227:20 pm -
1 stop20h 17m
Deal found 10/18![Allegiant Air logo]()
$391
This WAYA deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure WAYA is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/192:37 pm -
1 stop19h 41m
Mon 12/289:11 pm -
1 stop17h 05m
Deal found 10/15![Allegiant Air logo]()
$415
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:00 am -
1 stop4h 48m
Fri 11/206:08 pm -
1 stop6h 11m
Deal found 10/19![Delta logo]()
$419
This Delta deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:00 am -
1 stop4h 47m
Sat 10/314:00 pm -
1 stop5h 57m
Deal found 10/17![Delta logo]()
$434
This Delta deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:00 am -
1 stop6h 53m
Fri 10/306:10 pm -
1 stop6h 17m
Deal found 10/17![Delta logo]()
$449
This Delta deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:00 am -
1 stop6h 53m
Tue 10/276:10 pm -
1 stop6h 17m
Deal found 10/17![Delta logo]()
$464
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/251:50 pm -
1 stop24h 04m
Thu 10/298:36 pm -
1 stop18h 22m
Deal found 10/17![Allegiant Air logo]()
$482
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/251:50 pm -
1 stop24h 04m
Fri 10/308:29 am -
1 stop6h 29m
Deal found 10/17![Allegiant Air logo]()
$485
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/221:15 pm -
1 stop23h 58m
Thu 10/298:36 pm -
1 stop18h 22m
Deal found 10/17![Allegiant Air logo]()
$486
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/221:15 pm -
1 stop23h 58m
Fri 10/308:29 am -
1 stop6h 29m
Deal found 10/17![Allegiant Air logo]()
$490
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/711:12 am -
1 stop6h 03m
Tue 11/106:08 pm -
1 stop6h 11m
Deal found 10/18![Delta logo]()
$494
Best flights from Roanoke to Key WestDiscover carefully curated flight deals from Roanoke to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 20, 2026.
Discover carefully curated flight deals from Roanoke to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 20, 2026.
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected ” under the list of providers to see comparable flight deals.
Sat 11/146:00 am -
1 stop4h 48m
Fri 11/206:08 pm -
1 stop6h 11m
Deal found 10/18![Delta logo]()
$419
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/267:40 am -
2 stops11h 40m
Sun 1/316:26 pm -
1 stop4h 27m
Deal found 10/16![American Airlines logo]()
$687
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/178:05 pm -
2 stops21h 06m
Sun 12/201:35 pm -
1 stop5h 36m
Deal found 10/18![United Airlines logo]()
$732
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:00 am -
1 stop4h 48m
Sat 11/212:07 pm -
1 stop5h 11m
Deal found 10/15![Delta logo]()
$556
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/76:00 am -
1 stop4h 58m
Fri 3/126:00 pm -
1 stop6h 23m
Deal found 10/18![Delta logo]()
$617
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/201:10 pm -
1 stop5h 30m
Sat 3/277:22 pm -
1 stop4h 26m
Deal found 10/16![American Airlines logo]()
$712
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/306:47 am -
1 stop8h 35m
Wed 2/34:09 pm -
1 stop8h 36m
Deal found 10/18![United Airlines logo]()
$747
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/711:12 am -
1 stop6h 03m
Tue 11/106:08 pm -
1 stop6h 11m
Deal found 10/15![Delta logo]()
$633
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/137:00 am -
2 stops12h 43m
Tue 1/196:00 pm -
1 stop6h 23m
Deal found 10/15![Delta logo]()
$675
Last-minute flights from Roanoke to Key WestDiscover last-minute flight deals from Roanoke to Key West. Data last updated October 20, 2026 and is based on user searches.
Discover last-minute flight deals from Roanoke to Key West. Data last updated October 20, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/221:15 pm -
1 stop23h 58m
Thu 10/298:36 pm -
1 stop18h 22m
Deal found 10/17![Allegiant Air logo]()
$486
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/221:15 pm -
1 stop23h 58m
Fri 10/308:29 am -
1 stop6h 29m
Deal found 10/17![Allegiant Air logo]()
$490
This Delta deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:00 am -
1 stop4h 47m
Sat 10/314:00 pm -
1 stop5h 57m
Deal found 10/17![Delta logo]()
$434
This Delta deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:00 am -
1 stop4h 47m
Thu 10/296:10 pm -
1 stop6h 17m
Deal found 10/17![Delta logo]()
$464
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/233:48 pm -
2 stops45h 55m
Thu 10/298:36 pm -
1 stop18h 22m
Deal found 10/17![Allegiant Air logo]()
$498
This Delta deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:00 am -
1 stop6h 53m
Tue 10/276:10 pm -
1 stop6h 17m
Deal found 10/17![Delta logo]()
$449
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/251:50 pm -
1 stop24h 04m
Thu 10/298:36 pm -
1 stop18h 22m
Deal found 10/17![Allegiant Air logo]()
$482
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/251:50 pm -
1 stop24h 04m
Fri 10/308:29 am -
1 stop6h 29m
Deal found 10/17![Allegiant Air logo]()
$485
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/302:14 pm -
1 stop4h 35m
Tue 11/35:50 pm -
1 stop5h 01m
Deal found 10/15![American Airlines logo]()
$389
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/711:12 am -
1 stop6h 03m
Tue 11/106:08 pm -
1 stop6h 11m
Deal found 10/18![Delta logo]()
$494
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:00 am -
1 stop4h 48m
Fri 11/206:08 pm -
1 stop6h 11m
Deal found 10/19![Delta logo]()
$419
This Kiwi.com deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/154:12 pm -
1 stop21h 49m
Sun 11/227:20 pm -
1 stop20h 17m
Deal found 10/18![Allegiant Air logo]()
$391
One-way flights from Roanoke to Key WestSearch for one-way flight options from Roanoke to Key West. Find affordable one-way fares based on user searches. Data last updated October 20, 2026.
Search for one-way flight options from Roanoke to Key West. Find affordable one-way fares based on user searches. Data last updated October 20, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/198:32 pm -
1 stop18h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Allegiant Air logo]()
$273
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/66:00 am -
1 stop7h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Delta logo]()
$320
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:00 am -
2 stops10h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![American Airlines logo]()
$384
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/69:43 am -
2 stops9h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![American Airlines logo]()
$500
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/65:38 pm -
3 stops22h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![United Airlines logo]()
$707
Find flight deals from Roanoke to Key West
Discover tips and strategies to find the most affordable flight options for your journey from Roanoke (ROA) to Key West (EYW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 20, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $235 (Kiwi.com) |
Popular in | August |
Cheapest in | December |
Average price | $536 |
Cheapflights Fare Finder
Customize your flight search to find flights from Roanoke to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 20, 2026.
Use the filters below to find and compare flights from Roanoke to Key West that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
RoanokeKey West
ROA Roanoke - EYW Key West
ROAEYW
Roanoke
Sat 3/6
6:00 am-1:08 pm
1 stop7h 08m
Key West
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$320
RoanokeKey West
ROA Roanoke - EYW Key West
ROAEYW
Roanoke
Sat 11/14
6:00 am-10:48 am
1 stop4h 48m
Key West
Fri 11/20
6:08 pm-12:19 am
1 stop6h 11m
$419
RoanokeKey West
ROA Roanoke - EYW Key West
ROAEYW
Roanoke
Sat 3/6
9:43 am-7:08 pm
2 stops9h 25m
Key West
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$500
RoanokeKey West
ROA Roanoke - EYW Key West
ROAEYW
Roanoke
Sat 11/14
6:00 am-10:48 am
1 stop4h 48m
Key West
Sat 11/21
2:07 pm-7:18 pm
1 stop5h 11m
$556
RoanokeKey West
ROA Roanoke - EYW Key West
ROAEYW
Roanoke
Sun 3/7
6:00 am-10:58 am
1 stop4h 58m
Key West
Fri 3/12
6:00 pm-12:23 am
1 stop6h 23m
$617
RoanokeKey West
ROA Roanoke - EYW Key West
ROAEYW
Roanoke
Sat 11/7
11:12 am-5:15 pm
1 stop6h 03m
Key West
Tue 11/10
6:08 pm-12:19 am
1 stop6h 11m
$633
RoanokeKey West
ROA Roanoke - EYW Key West
ROAEYW
Roanoke
Wed 1/13
7:00 am-7:43 pm
2 stops12h 43m
Key West
Tue 1/19
6:00 pm-12:23 am
1 stop6h 23m
$675
RoanokeKey West
ROA Roanoke - EYW Key West
ROAEYW
Roanoke
Thu 11/19
8:32 pm-4:28 pm
3 stops43h 56m
Key West
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$686
RoanokeKey West
ROA Roanoke - EYW Key West
ROAEYW
Roanoke
Tue 1/26
7:40 am-7:20 pm
2 stops11h 40m
Key West
Sun 1/31
6:26 pm-10:53 pm
1 stop4h 27m
$687
RoanokeKey West
ROA Roanoke - EYW Key West
ROAEYW
Roanoke
Sat 3/6
5:38 pm-3:55 pm
3 stops22h 17m
Key West
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$707
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from Roanoke to Key West
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Roanoke to Key West in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Roanoke-Key West flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Roanoke-Key West flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Roanoke-Key West flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Roanoke-Key West flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Roanoke-Key West flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Roanoke to Key West
Have a flexible travel schedule? Discover the best time to fly to Key West from Roanoke with our price prediction graph.
ROA-EYW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Roanoke to Key West
Reviews of airlines servicing Key West
Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated October 20, 2026.
Read through reviews of airlines operating flights from Roanoke to Key West, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Comfort
7.8
Crew
8.5
Entertainment
7.8
Food
7.2
Overall
7.8
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Boarding
8.1
Comfort
7.8
Crew
8.5
Entertainment
7.8
Food
7.2
Overall
7.8
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Boarding
8.1
Comfort
7.8
Crew
8.5
Entertainment
7.8
Food
7.2
Overall
7.8
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Related info for your journey
Find useful and relevant information for your journey from Roanoke to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Complete your trip
Complete your trip to Key West by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Roanoke to Key West by cabin class
Find flights from Roanoke to Key West, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Key West
Explore flights to Key West departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 20, 2026.
Roanoke and Key West flights
Browse other Roanoke and Key West flight options. Last updated on October 20, 2026.
Other flights from Roanoke
Browse through other flights departing from Roanoke. Flights are based on user searches made on Cheapflights and were last updated on October 20, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Roanoke to Key West
Discover the top 2 airlines that operate flights from Roanoke to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 20, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$248 | Average$556 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$283 | Average$583 | FlexibilityNo cancel fee | On-timeN/A |