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Key Largo

$127+ Cheap flights from Islip (ISP) to Key Largo, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/9. Fares are subject to change and may not be available on all flights or dates of travel.
ISP — MIA
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheapflights Tip: The best prices from Islip Long Island to Key Largo are usually found in January or October, booked 28 days in advance, depart on a Tuesday or Thursday and return on a Thursday

Cheap flight deals from Islip to Key Largo

Keep the following information in mind while searching for Islip to Key Largo flight deals. Data was last updated September 15, 2025.

Round-trip from

$226
(Frontier)

One-way from

$127
(Kiwi.com)

Popular in

April

Cheapest in

January

Average price

$411
From Islip Long Island to Key Largo
Search Deals
One-way flight from Islip Long Island to Key Largo
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($16 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Islip to Key Largo

Cheapest flights from Islip to Key Largo
Explore the most affordable flight options available from Islip to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This Frontier deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/306:37 pmISP - MIA
2 stops46h 48mFrontier
Mon 11/37:07 pmMIA - ISP
2 stops22h 35mFrontier
Deal found 9/13$224
This Frontier deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/211:40 amISP - MIA
2 stops20h 49mFrontier
Mon 10/69:16 pmMIA - ISP
2 stops23h 26mFrontier
Deal found 9/15$227
This Frontier deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/269:47 pmISP - MIA
2 stops12h 47mFrontier
Mon 11/310:15 pmMIA - ISP
2 stops19h 27mFrontier
Deal found 9/14$240
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/275:55 amISP - MIA
1 stop6h 00mSouthwest
Tue 11/45:10 pmMIA - ISP
1 stop4h 55mSouthwest
Deal found 9/14$257
This Frontier deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/29:27 pmISP - MIA
2 stops12h 44mFrontier
Sun 11/910:15 pmMIA - ISP
2 stops20h 51mFrontier
Deal found 9/15$282
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/156:00 amISP - MIA
1 stop4h 55mSouthwest
Sat 10/186:00 amMIA - ISP
1 stop6h 10mSouthwest
Deal found 9/13$287
This Frontier deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/109:54 amISP - MIA
2 stops14h 40mFrontier
Sat 11/151:58 pmMIA - ISP
2 stops18h 04mFrontier
Deal found 9/14$291
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/512:55 pmISP - MIA
2 stops8h 55mSouthwest
Wed 11/126:55 amMIA - ISP
2 stops8h 25mSouthwest
Deal found 9/13$297
This Frontier deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/129:44 amISP - MIA
2 stops11h 52mFrontier
Sun 10/194:16 pmMIA - ISP
2 stops16h 48mFrontier
Deal found 9/13$305
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/14:00 pmISP - MIA
1 stop5h 10mSouthwest
Tue 10/711:45 amMIA - ISP
1 stop4h 20mSouthwest
Deal found 9/15$307
This Frontier deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/136:37 pmISP - MIA
2 stops15h 34mFrontier
Sun 11/166:00 amMIA - ISP
2 stops14h 42mFrontier
Deal found 9/15$309

Cheapflights Fare Finder

 
Customize your flight search to find flights from Islip to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Islip to Key Largo that are best for you.

Fly from

Islip

Fly to

Key Largo

Route

Depart

Return

Price

IslipMiami

ISP - MIA

ISPMIA

Islip Long Island

Thu 10/16

9:37 pm-4:03 pm

2 stops18h 26m

Miami

Mon 10/20

4:21 pm-9:44 am

2 stops17h 23m

$226

IslipMiami

ISP - MIA

ISPMIA

Islip Long Island

Mon 10/27

5:55 am-11:55 am

1 stop6h 00m

Miami

Tue 11/4

5:10 pm-10:05 pm

1 stop4h 55m

$257

IslipMiami

ISP - MIA

ISPMIA

Islip Long Island

Thu 1/1

3:40 pm-10:05 pm

1 stop6h 25m

Miami

Tue 1/6

4:30 pm-9:55 pm

1 stop5h 25m

$257

IslipMiami

ISP - MIA

ISPMIA

Islip Long Island

Fri 10/3

5:35 pm-10:35 pm

1 stop5h 00m

Miami

Tue 10/7

6:55 am-4:05 pm

2 stops9h 10m

$312

IslipMiami

ISP - MIA

ISPMIA

Islip Long Island

Sat 10/4

3:10 pm-8:30 pm

1 stop5h 20m

Miami

Sat 10/11

6:00 am-4:15 pm

1 stop10h 15m

$312

IslipMiami

ISP - MIA

ISPMIA

Islip Long Island

Wed 10/1

4:00 pm-9:10 pm

1 stop5h 10m

Miami

Tue 10/7

6:55 am-4:05 pm

2 stops9h 10m

$312

IslipMiami

ISP - MIA

ISPMIA

Islip Long Island

Sun 11/2

9:27 pm-10:11 am

2 stops12h 44m

Miami

Sun 11/9

10:15 pm-7:06 pm

2 stops20h 51m

$316

IslipMiami

ISP - MIA

ISPMIA

Islip Long Island

Thu 11/13

1:40 pm-10:05 pm

2 stops8h 25m

Miami

Tue 11/18

12:40 pm-10:05 pm

2 stops9h 25m

$317

IslipMiami

ISP - MIA

ISPMIA

Islip Long Island

Tue 1/6

3:45 pm-9:00 pm

1 stop5h 15m

Miami

Sun 1/11

6:30 am-11:55 am

1 stop5h 25m

$327

IslipMiami

ISP - MIA

ISPMIA

Islip Long Island

Thu 10/9

5:35 pm-10:35 pm

1 stop5h 00m

Miami

Thu 10/23

7:05 pm-11:45 pm

1 stop4h 40m

$327

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Showing 1-10 of 15 results
1
2

Best time to book a flight from Islip to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from Islip with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Islip to Key Largo

What is the cheapest month to book a flight from Islip to Key Largo?

Currently, September is the cheapest month in which you can book a flight from Islip to Key Largo (average of $232). Flying from Islip to Key Largo in March is currently the most expensive (average of $289). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ISP to KE9?

Find hourly flight availability from Islip to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Islip to Key Largo as you normally would.

What is the cheapest day to fly from Islip to Key Largo?

Use this chart to determine the cheapest time to fly round-trip from Islip to Key Largo. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Islip to Key Largo flight should consider departing on Monday at noon when fares are most often at their lowest. Saturday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Key Largo

Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated September 15, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and JetBlue from Islip to Key Largo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

8.0

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,242 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

8.0

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,954 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

8.0

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
JetBlue
7.2
Good
2,912 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

8.0

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Spirit Airlines
6.3
Okay
8,015 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

8.0

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Frontier
5.8
Fair
3,172 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

8.0

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Islip to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Islip to Key Largo?

    For a flight from Islip to Key Largo, you will be flying from Long Island. Islip Long Island (ISP) is just 7.2 mi from the center of the city. Long Island is the only Islip airport and it handles 0 outbound flights to Key Largo per day. 5 airlines have flights to Key Largo from Islip Long Island on a regular basis.

  • How popular is this Islip to Key Largo flight route?

    The Islip Long Island to Key Largo flight path was viewed by 2 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Islip to Key Largo?

    For as low as $257, Frontier can have you in Key Largo from Islip in 6h. Islip and Key Largo are separated by a distance of 1114 mi. This flight may include one or multiple stops.

  • What are the cheapest flights from Islip to Key Largo?

    While on average a flight from Islip to Key Largo is generally $463, our data shows the cheapest flight currently is $463. When looking at the most popular route, (Islip Long Island - Miami), you can expect to pay $257 for that flight.

  • Can I find deals for flights from Islip to Key Largo that include hotel bookings?

    Yes. In addition to deals on Islip to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Islip to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Islip to Key Largo.

  • Can I find deals for business class flights from Islip to Key Largo?

    Yes. Cheapflights offers flight deals from Islip to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Islip to Key Largo?

    Currently, September is the cheapest month in which you can book a flight from Islip to Key Largo (average of $232). Flying from Islip to Key Largo in March is currently the most expensive (average of $289). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Islip to Key Largo

Discover the top 5 airlines that operate flights from Islip to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$45Average$143FlexibilityNo cancel feeOn-time62%
Spirit AirlinesCheapest$60Average$176FlexibilityNo cancel feeOn-time65%
DeltaCheapest$98Average$249FlexibilityNo cancel feeOn-timeN/A
JetBlueCheapest$116Average$312FlexibilityNo cancel feeOn-time62%
SouthwestCheapest$186Average$410FlexibilityNo cancel feeOn-time63%

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