Key Largo

$95+ Cheap flights from Knoxville (TYS) to Key Largo, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/5. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MIA
jun. 12 — jun. 191
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Cheapflights Tip: The best prices from Knoxville McGhee Tyson to Key Largo are usually found in February or August, booked 74 days in advance, depart on a Friday or Saturday and return on a Wednesday

Cheap flight deals from Knoxville to Key Largo

Cheapest flights from Knoxville to Key Largo
Explore the most affordable flight options available from Knoxville to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on mai 13, 2026.

This Orbitz deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
on. 8/58:32 pm
TYS
-
MIA
1 stop9h 19m
Frontier
ma. 8/106:00 am
MIA
-
TYS
1 stop13h 36m
Frontier
Deal found 5/10$210
This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lø. 8/221:54 pm
TYS
-
MIA
2 stops23h 35m
Multiple Airlines
sø. 8/309:38 pm
MIA
-
TYS
1 stop20h 27m
Multiple Airlines
Deal found 5/8$244
This Frontier deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ma. 6/18:32 pm
TYS
-
MIA
1 stop9h 01m
Frontier
fr. 6/56:30 am
MIA
-
TYS
1 stop13h 03m
Frontier
Deal found 5/12$260
This Kiwi.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sø. 7/263:38 pm
TYS
-
MIA
1 stop28h 55m
Multiple Airlines
fr. 7/318:30 am
MIA
-
TYS
2 stops13h 30m
Multiple Airlines
Deal found 5/9$262
This Expedia deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
fr. 6/58:32 pm
TYS
-
MIA
1 stop9h 01m
Frontier
fr. 6/126:00 am
MIA
-
TYS
1 stop13h 37m
Frontier
Deal found 5/8$270
This Kiwi.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ma. 6/112:55 pm
TYS
-
MIA
1 stop9h 17m
Multiple Airlines
fr. 6/59:15 am
MIA
-
TYS
1 stop13h 25m
Multiple Airlines
Deal found 5/11$271
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
on. 8/58:32 pm
TYS
-
MIA
1 stop9h 19m
Multiple Airlines
ma. 8/108:30 am
MIA
-
TYS
2 stops13h 54m
Multiple Airlines
Deal found 5/10$295
This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
to. 10/86:15 am
TYS
-
MIA
2 stops14h 18m
Multiple Airlines
lø. 10/172:23 pm
MIA
-
TYS
1 stop26h 58m
Multiple Airlines
Deal found 5/8$297
This Southwest deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ti. 6/98:10 am
TYS
-
MIA
1 stop6h 15m
Southwest
ti. 6/161:45 pm
MIA
-
TYS
1 stop7h 30m
Southwest
Deal found 5/11$307
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lø. 8/227:50 am
TYS
-
MIA
1 stop5h 45m
Southwest
lø. 8/299:40 am
MIA
-
TYS
1 stop9h 40m
Southwest
Deal found 5/8$316

Find flight deals from Knoxville to Key Largo

Keep the following information in mind while searching for Knoxville to Key Largo flight deals. Data was last updated mai 13, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$210
(Orbitz)

One-way from

$95
(Frontier)

Popular in

March

Cheapest in

February

Average price

$440
Provider with most accurate pricing for Knoxville McGhee Tyson-Miami flight deals.
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Miami flights.
From Knoxville McGhee Tyson to Key Largo
One-way flight from Knoxville McGhee Tyson to Key Largo
Highest demand for flights based on searches. 3% potential increase in price ($13 potential increase over avg. RT price).
Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
Average for round-trip flights in May 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated mai 13, 2026.
Use the filters below to find and compare flights from Knoxville to Key Largo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

ma. 6/8

7:30 am-10:05 pm

2 stops14h 35m

Miami

fr. 6/12

7:15 am-9:10 pm

2 stops13h 55m

$356

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

to. 10/8

7:10 am-6:25 pm

2 stops11h 15m

Miami

ti. 10/20

9:05 am-4:45 pm

2 stops7h 40m

$364

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

lø. 7/4

8:00 am-7:20 pm

2 stops11h 20m

Miami

lø. 7/11

6:10 am-11:55 am

2 stops5h 45m

$367

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

to. 6/11

12:35 pm-11:15 pm

2 stops10h 40m

Miami

ma. 6/15

7:15 am-9:10 pm

2 stops13h 55m

$373

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

ma. 6/8

7:30 am-2:20 pm

1 stop6h 50m

Miami

lø. 6/13

6:10 am-4:40 pm

1 stop10h 30m

$379

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

fr. 6/5

7:30 am-2:20 pm

1 stop6h 50m

Miami

fr. 6/12

7:15 am-9:10 pm

2 stops13h 55m

$388

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

fr. 10/9

12:50 pm-10:40 pm

2 stops9h 50m

Miami

lø. 10/17

6:40 am-5:40 pm

2 stops11h 00m

$395

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

to. 6/25

6:40 am-2:35 pm

1 stop7h 55m

Miami

sø. 6/28

10:05 am-9:15 pm

1 stop11h 10m

$400

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

to. 5/28

12:15 pm-11:00 pm

2 stops10h 45m

Miami

ma. 6/1

12:05 pm-9:15 pm

1 stop9h 10m

$407
Quickest round-trip

KnoxvilleMiami

TYS - MIA

TYSMIA

Knoxville McGhee Tyson

to. 6/11

7:30 am-2:20 pm

1 stop6h 50m

Miami

to. 6/18

3:05 pm-10:30 pm

1 stop7h 25m

$417

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/12

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

Best time to book a flight from Knoxville to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Key Largo

What is the cheapest time of day to fly from TYS to KE9?

Find hourly flight availability from Knoxville to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated mai 13, 2026.

A simple way to save on the total cost of your ticket is to fly from Knoxville to Key Largo at noon. If you’re flexible enough to do this you can expect to save up to 47% on your trip compared to booking a flight in the evening.

What is the cheapest day to fly from Knoxville to Key Largo?

Use this chart to determine the cheapest time to fly round-trip from Knoxville to Key Largo. Price data was last updated on May 9, 2026.

Travelers seeking maximum savings on their Knoxville to Key Largo flight should consider departing on Monday afternoons when fares are most often at their lowest. Monday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Knoxville to Key Largo

Explore weekly flight availability from Knoxville to Key Largo. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated mai 13, 2026.

The most flights from TYS to KE9 are scheduled on a Monday (1 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (1 on average).

How much does it cost to fly round-trip from Knoxville to Key Largo?

Reviews of airlines servicing Key Largo

Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated mai 13, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andAllegiant Air from Knoxville to Key Largo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Boarding

8.1

Food

7.0

Overall

7.9

Crew

8.6

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Boarding

8.1

Food

7.0

Overall

7.9

Crew

8.6

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Boarding

8.1

Food

7.0

Overall

7.9

Crew

8.6

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Boarding

8.1

Food

7.0

Overall

7.9

Crew

8.6

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Boarding

8.1

Food

7.0

Overall

7.9

Crew

8.6

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Knoxville to Key Largo?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Key Largo. You should not have trouble finding flights to Key Largo from McGhee Tyson; the airport handles an average of 1 outbound flight to Key Largo per day. You should also have plenty of airline options to choose from since 4 airlines have flights from the Knoxville airport to Key Largo. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • How popular is this Knoxville to Key Largo flight route?

  • How long is the flight from Knoxville to Key Largo?

    A quick flight from Knoxville to Key Largo can take about 6h 15m. Southwest provides one of the quickest options available for as low as $312. Airlines will cover a distance of 725 mi.

  • What are the cheapest airlines to fly from Knoxville to Key Largo one-way?

    To fly one-way, consider booking your trip with Allegiant Air, which is currently one of the cheapest options available, starting at $67. Delta flights start at $89 while deals on American Airlines start at $193 one-way.

  • What are the most reliable airlines from Knoxville to Key Largo?

    Consider Qatar Airways (96%), American Airlines (95%) or Envoy Air (95%) when booking your flight. These represent the most reliable airlines when flying from Knoxville to Key Largo.

  • What are the cheapest flights from Knoxville to Key Largo?

    Looking for the cheapest flight from Knoxville to Key Largo? While on average our users pay $495, our data indicates the cheapest price to be $155. The most popular route (Knoxville McGhee Tyson - Miami), is priced around $320.

  • Can I find deals for flights from Knoxville to Key Largo that include hotel bookings?

    Yes. In addition to deals on Knoxville to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Key Largo.

  • Can I find deals for business class flights from Knoxville to Key Largo?

    Yes. Cheapflights offers flight deals from Knoxville to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Knoxville to Key Largo

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Knoxville to Key Largo

Discover the top 4 airlines that operate flights from Knoxville to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated mai 13, 2026.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$82Average$193FlexibilityNo cancel feeOn-time88%
DeltaCheapest$178Average$438FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$228Average$390FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$306Average$366FlexibilityNo cancel feeOn-time63%

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