HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Johnson City

$324+ Cheap flights from Des Moines (DSM) to Johnson City, TN, TN

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/27. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — TYS
Mar 15 — Mar 221
Sun 3/15
Sun 3/22
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Des Moines to Johnson City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Des Moines to Johnson City

Cheapest flights from Des Moines to Johnson City
Explore the most affordable flight options available from Des Moines to Johnson City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 13, 2026.

This Delta deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/275:15 pm
DSM
-
TRI
1 stop4h 07m
Delta
Tue 3/31:02 pm
TRI
-
DSM
2 stops8h 47m
Delta
Deal found 2/12$324
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/316:29 pm
DSM
-
TRI
1 stop4h 29m
American Airlines
Wed 6/108:25 pm
TRI
-
DSM
1 stop4h 34m
American Airlines
Deal found 2/11$393
This American Airlines deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/271:48 pm
DSM
-
TRI
2 stops8h 59m
American Airlines
Tue 3/33:26 pm
TRI
-
DSM
2 stops7h 53m
American Airlines
Deal found 2/12$511
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/277:00 am
DSM
-
TRI
1 stop6h 21m
American Airlines
Fri 4/35:30 am
TRI
-
DSM
1 stop6h 04m
American Airlines
Deal found 2/10$526

Find flight deals from Des Moines to Johnson City

Keep the following information in mind while searching for Des Moines to Johnson City flight deals. Data was last updated February 13, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$324
(Delta)
Provider with most accurate pricing for Des Moines-Blountville Tri Cities TN/VA flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Blountville Tri Cities TN/VA flights.
Search Deals
From Des Moines to Johnson City
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Johnson City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 13, 2026.
Use the filters below to find and compare flights from Des Moines to Johnson City that are best for you.

Fly from

Des Moines

Fly to

Johnson City

Route

Depart

Return

Price

Des MoinesBlountville

DSM - TRI

DSMTRI

Des Moines

Fri 2/27

5:15 pm-10:22 pm

1 stop4h 07m

Blountville Tri Cities TN/VA

Tue 3/3

1:02 pm-8:49 pm

2 stops8h 47m

$324

Des MoinesBlountville

DSM - TRI

DSMTRI

Des Moines

Sun 5/31

6:29 pm-11:58 pm

1 stop4h 29m

Blountville Tri Cities TN/VA

Wed 6/10

8:25 pm-11:59 pm

1 stop4h 34m

$393

Des MoinesBlountville

DSM - TRI

DSMTRI

Des Moines

Fri 2/27

1:48 pm-11:47 pm

2 stops8h 59m

Blountville Tri Cities TN/VA

Tue 3/3

3:26 pm-10:19 pm

2 stops7h 53m

$511

Des MoinesBlountville

DSM - TRI

DSMTRI

Des Moines

Fri 3/27

7:00 am-2:21 pm

1 stop6h 21m

Blountville Tri Cities TN/VA

Fri 4/3

5:30 am-10:34 am

1 stop6h 04m

$526

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/12

Best time to book a flight from Des Moines to Johnson City

Have a flexible travel schedule? Discover the best time to fly to Johnson City from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Johnson City

What is the cheapest month to book a flight from Des Moines to Johnson City?

Currently, November is the cheapest month in which you can book a flight from Des Moines to Johnson City (average of $203). Flying from Des Moines to Johnson City in January is currently the most expensive (average of $304). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Johnson City

Get insights into the airlines that provide service to Johnson City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Johnson City. Reviews last updated February 13, 2026.
Get a feel of what it's like to fly with American Airlines from Des Moines to Johnson City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,275 reviews

Entertainment

6.9

Overall

7.2

Boarding

7.5

Comfort

7.2

Crew

8.0

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
American Airlines
7.2
Good
11,275 reviews
American Airlines
7.2
Good
11,275 reviews

Entertainment

6.9

Overall

7.2

Boarding

7.5

Comfort

7.2

Crew

8.0

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Johnson City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Johnson City?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly out of when you book flights from Des Moines to Johnson City. 3 airlines have flights from Des Moines to Johnson City on a regular basis. Booking flights from Des Moines to Johnson City should not be difficult; the airport handles an average of 0 outbound flights to Johnson City per day.

  • How long is the flight from Des Moines to Johnson City?

    There are many flights that can get you from Des Moines to Johnson City in 4h 07m. Fly via Delta or American Airlines to get the fastest option. There are 697 mi between Des Moines and Johnson City. This flight may include one or multiple stops.

  • Can I find deals for flights from Des Moines to Johnson City that include hotel bookings?

    Yes. In addition to deals on Des Moines to Johnson City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Johnson City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Johnson City.

  • Can I find deals for business class flights from Des Moines to Johnson City?

    Yes. Cheapflights offers flight deals from Des Moines to Johnson City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Johnson City?

    Currently, November is the cheapest month in which you can book a flight from Des Moines to Johnson City (average of $203). Flying from Des Moines to Johnson City in January is currently the most expensive (average of $304). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 3 airlines flying from Des Moines to Johnson City

Discover the top 3 airlines that operate flights from Des Moines to Johnson City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 13, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$203Average$415FlexibilityNo cancel feeOn-time71%
DeltaCheapest$203Average$378FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$300Average$498FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.
Site
Cookie settings©2026 Cheapflights