Jacksonville

$75+ Cheap flights from Missouri to Jacksonville (JAX)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/9. Fares are subject to change and may not be available on all flights or dates of travel.
STL — JAX
Aug 19 — Aug 261
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Missouri to Jacksonville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Missouri to Jacksonville

Keep the following information in mind while searching for Missouri to Jacksonville flight deals. Data was last updated August 14, 2025.

Round-trip from

$191
(Delta)

One-way from

$75
(Priceline)

Popular in

March

Cheapest in

January

Average price

$342

Good round-trip deal

$203 or less

Good one-way deal

$158 or less
From Missouri to Jacksonville
One-way flight from Missouri to Jacksonville
Highest demand for flights based on searches. 12% potential increase in price ($54 potential increase over avg. RT price).
Cheapest flight prices on average. 4% potential price decrease ($18 potential savings vs. average RT price).
Average for round-trip flights in August 2025
Price to beat on a round-trip flight from Missouri to Jacksonville.
Price to beat on a one-way flight from Missouri to Jacksonville.

Find flight deals from Missouri to Jacksonville

Cheapest flights from Missouri to Jacksonville
Explore the most affordable flight options available from Missouri to Jacksonville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/246:01 amSTL - JAX
1 stop6h 24mDelta
Wed 10/18:20 amJAX - STL
1 stop5h 01mDelta
Deal found 8/14$191
This Southwest deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/187:25 pmSTL - JAX
Nonstop1h 55mSouthwest
Tue 9/236:45 pmJAX - STL
Nonstop2h 15mSouthwest
Deal found 8/14$195
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/93:59 pmSTL - JAX
1 stop5h 56mAmerican Airlines
Tue 9/163:06 pmJAX - STL
2 stops6h 26mAmerican Airlines
Deal found 8/12$196
This Southwest deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/18:40 amSTL - JAX
1 stop4h 05mSouthwest
Mon 10/67:55 amJAX - STL
Nonstop2h 10mSouthwest
Deal found 8/13$201
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/46:29 amSTL - JAX
1 stop6h 47mAmerican Airlines
Tue 10/75:20 pmJAX - STL
1 stop6h 45mAmerican Airlines
Deal found 8/12$205
This Southwest deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/158:15 amSTL - JAX
Nonstop2h 00mSouthwest
Thu 9/187:35 pmJAX - STL
Nonstop2h 10mSouthwest
Deal found 8/14$209
This United Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/138:20 amSTL - JAX
1 stop6h 14mUnited Airlines
Mon 11/174:57 pmJAX - STL
1 stop6h 02mUnited Airlines
Deal found 8/11$214
This Southwest deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/128:15 amSTL - JAX
Nonstop2h 00mSouthwest
Mon 9/157:20 amJAX - STL
Nonstop2h 10mSouthwest
Deal found 8/13$217
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/145:27 amSTL - JAX
1 stop3h 54mAmerican Airlines
Wed 10/88:05 amJAX - STL
1 stop5h 01mAmerican Airlines
Deal found 8/12$218
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/242:05 pmSGF - JAX
1 stop6h 54mAmerican Airlines
Wed 10/18:21 amJAX - SGF
1 stop4h 46mAmerican Airlines
Deal found 8/14$241
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/95:59 pmSGF - JAX
1 stop5h 00mDelta
Tue 9/165:01 pmJAX - SGF
1 stop6h 01mDelta
Deal found 8/13$245
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/247:12 amMCI - JAX
1 stop5h 13mAmerican Airlines
Wed 10/17:18 amJAX - MCI
1 stop7h 55mAmerican Airlines
Deal found 8/13$245

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Jacksonville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
Use the filters below to find and compare flights from Missouri to Jacksonville that are best for you.

Fly from

Missouri

Fly to

Jacksonville

Route

Depart

Return

Price

St. LouisJacksonville

STL - JAX

STLJAX

Lambert-St Louis

Wed 9/24

8:17 am-2:16 pm

1 stop4h 59m

Jacksonville

Wed 10/1

11:42 am-6:22 pm

1 stop7h 40m

$191

St. LouisJacksonville

STL - JAX

STLJAX

Lambert-St Louis

Wed 10/8

7:05 am-12:21 pm

1 stop4h 16m

Jacksonville

Wed 10/15

10:04 am-12:35 pm

1 stop3h 31m

$191

St. LouisJacksonville

STL - JAX

STLJAX

Lambert-St Louis

Wed 9/24

7:10 am-11:40 am

1 stop3h 30m

Jacksonville

Wed 10/1

11:52 am-4:37 pm

1 stop5h 45m

$191

St. LouisJacksonville

STL - JAX

STLJAX

Lambert-St Louis

Tue 10/28

6:25 am-11:44 am

1 stop4h 19m

Jacksonville

Tue 10/28

5:20 pm-11:05 pm

1 stop6h 45m

$191

St. LouisJacksonville

STL - JAX

STLJAX

Lambert-St Louis

Tue 9/9

6:00 am-1:29 pm

1 stop6h 29m

Jacksonville

Tue 9/16

6:00 am-12:19 pm

1 stop7h 19m

$191

St. LouisJacksonville

STL - JAX

STLJAX

Lambert-St Louis

Tue 10/28

6:00 am-12:21 pm

1 stop5h 21m

Jacksonville

Wed 10/29

5:10 am-10:26 am

1 stop6h 16m

$191

St. LouisJacksonville

STL - JAX

STLJAX

Lambert-St Louis

Wed 10/1

6:40 pm-9:35 pm

Nonstop1h 55m

Jacksonville

Mon 10/6

8:15 pm-9:25 pm

Nonstop2h 10m

$195

St. LouisJacksonville

STL - JAX

STLJAX

Lambert-St Louis

Thu 9/18

8:15 am-11:15 am

Nonstop2h 00m

Jacksonville

Tue 9/23

6:45 pm-8:00 pm

Nonstop2h 15m

$195

St. LouisJacksonville

STL - JAX

STLJAX

Lambert-St Louis

Tue 9/9

3:59 pm-10:55 pm

1 stop5h 56m

Jacksonville

Tue 9/16

3:06 pm-8:32 pm

2 stops6h 26m

$196

SpringfieldJacksonville

SGF - JAX

SGFJAX

Springfield-Branson

Wed 9/24

2:05 pm-9:59 pm

1 stop6h 54m

Jacksonville

Wed 10/1

7:18 am-11:33 am

1 stop5h 15m

$241

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/14

Showing 1-10 of 45 results
1
2
3
...
5

Best time to book a flight from Missouri to Jacksonville

Have a flexible travel schedule? Discover the best time to fly to Jacksonville from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Jacksonville

What is the cheapest month to book a flight from Missouri to Jacksonville?

Currently, August is the cheapest month in which you can book a flight from Missouri to Jacksonville (average of $278). Flying from Missouri to Jacksonville in March is currently the most expensive (average of $365). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to JAX?

Find hourly flight availability from Missouri to Jacksonville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 14, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Jacksonville as you normally would.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Jacksonville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Jacksonville from Missouri?

    Most people fly into Jacksonville (JAX) if they book a flight to Jacksonville from Missouri. Jacksonville is conveniently located just 11.2 mi from Jacksonville’s city center.

  • How popular is this Missouri to Jacksonville flight route?

  • What are the cheapest airlines to fly from Missouri to Jacksonville one-way?

    To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $75. Southwest flights start at $91 while deals on Allegiant Air start at $184 one-way.

  • What are the most popular routes from Missouri to Jacksonville?

  • What are the cheapest flights from Missouri to Jacksonville?

    On average you can expect to pay $326 for a flight from Missouri to Jacksonville. The cheapest flight overall is $82 while the most popular route, (Kansas City - Jacksonville) is currently priced at $253.

  • Can I find deals for flights from Missouri to Jacksonville that include hotel bookings?

    Yes. In addition to deals on Missouri to Jacksonville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Jacksonville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Jacksonville.

  • Can I find deals for business class flights from Missouri to Jacksonville?

    Yes. Cheapflights offers flight deals from Missouri to Jacksonville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Jacksonville?

    Currently, August is the cheapest month in which you can book a flight from Missouri to Jacksonville (average of $278). Flying from Missouri to Jacksonville in March is currently the most expensive (average of $365). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Jacksonville?

Book flights to Jacksonville if you plan to visit one of these locations
Jacksonville Beach
Orange Park
Kingsland
Fernandina Beach
Waycross

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Missouri to Jacksonville

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Missouri to Jacksonville

Discover the top 4 airlines that operate flights from Missouri to Jacksonville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$186Average$350FlexibilityNo cancel feeOn-time71%
DeltaCheapest$218Average$356FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$221Average$366FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$278Average$369FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.