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$71+ Cheap flights from Missouri to Jacksonville (JAX)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/7. Fares are subject to change and may not be available on all flights or dates of travel.
STL — JAX
nov. 5 — nov. 121
mié. 11/5
mié. 11/12
1 adult, Economy
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Cheap flight deals from Missouri to Jacksonville

Keep the following information in mind while searching for Missouri to Jacksonville flight deals. Data was last updated octubre 6, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$231
(Kiwi.com)

One-way from

$71
(Trip.com)

Popular in

December

Cheapest in

October

Average price

$275

Good round-trip deal

$267 or less

Good one-way deal

$129 or less
Provider with most accurate pricing for Lambert-St Louis-Jacksonville flight deals.
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Provider most trusted by Cheapflights users for Lambert-St Louis-Jacksonville flights.
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From Missouri to Jacksonville
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One-way flight from Missouri to Jacksonville
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Highest demand for flights based on searches. 9% potential increase in price ($34 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Price to beat on a round-trip flight from Missouri to Jacksonville.
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Price to beat on a one-way flight from Missouri to Jacksonville.
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Find flight deals from Missouri to Jacksonville

Cheapest flights from Missouri to Jacksonville
Explore the most affordable flight options available from Missouri to Jacksonville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 6, 2025.

This Southwest deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/288:15 amSTL - JAX
Nonstop1h 55mSouthwest
mar. 10/286:50 pmJAX - STL
Nonstop2h 10mSouthwest
Deal found 10/5$237
This Kiwi.com deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/212:20 pmSTL - JAX
1 stop28h 49mMultiple Airlines
dom. 11/912:03 pmJAX - STL
2 stops46h 04mMultiple Airlines
Deal found 10/5$241
This United Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/288:20 amSTL - JAX
1 stop6h 14mUnited Airlines
jue. 10/304:57 pmJAX - STL
1 stop6h 25mUnited Airlines
Deal found 10/4$242
This American Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/296:27 amSGF - JAX
1 stop4h 17mAmerican Airlines
mar. 11/411:20 amJAX - SGF
1 stop6h 44mAmerican Airlines
Deal found 10/5$245
This Delta deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/286:00 amSTL - JAX
1 stop5h 40mDelta
mar. 10/285:32 pmJAX - STL
1 stop5h 32mDelta
Deal found 10/5$247
This American Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/205:00 amSTL - JAX
1 stop5h 42mAmerican Airlines
jue. 11/276:45 amJAX - STL
2 stops10h 40mAmerican Airlines
Deal found 10/5$253
This Southwest deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/288:15 amSTL - JAX
Nonstop1h 55mSouthwest
jue. 10/308:15 pmJAX - STL
Nonstop2h 10mSouthwest
Deal found 10/4$254
This Kiwi.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 10/2611:32 amSTL - JAX
1 stop4h 38mMultiple Airlines
dom. 11/212:03 pmJAX - STL
2 stops46h 04mMultiple Airlines
Deal found 10/6$268
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/188:00 amSGF - JAX
2 stops11h 10mUnited Airlines
dom. 11/234:57 pmJAX - SGF
1 stop5h 49mUnited Airlines
Deal found 10/5$274
This Kiwi.com deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 10/2611:32 amSTL - JAX
1 stop4h 38mFrontier
vie. 10/317:04 pmJAX - STL
2 stops15h 03mFrontier
Deal found 10/3$274
This Southwest deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/46:10 pmSTL - JAX
Nonstop1h 55mSouthwest
dom. 12/77:10 pmJAX - STL
Nonstop2h 20mSouthwest
Deal found 10/5$277
This Delta deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/237:02 pmSTL - JAX
1 stop3h 54mDelta
mié. 12/316:00 amJAX - STL
1 stop3h 58mDelta
Deal found 10/4$278

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Jacksonville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 6, 2025.
Use the filters below to find and compare flights from Missouri to Jacksonville that are best for you.

Fly from

Missouri

Fly to

Jacksonville

Route

Depart

Return

Price

St. LouisJacksonville

STL - JAX

STLJAX

Lambert-St Louis

mar. 10/28

8:15 am-11:10 am

Nonstop1h 55m

Jacksonville

mar. 10/28

6:50 pm-8:00 pm

Nonstop2h 10m

$237

SpringfieldJacksonville

SGF - JAX

SGFJAX

Springfield-Branson

mié. 10/29

6:27 am-11:44 am

1 stop4h 17m

Jacksonville

mar. 11/4

11:20 am-5:04 pm

1 stop6h 44m

$245

SpringfieldJacksonville

SGF - JAX

SGFJAX

Springfield-Branson

mar. 11/18

3:20 pm-9:22 pm

1 stop5h 02m

Jacksonville

dom. 11/23

4:57 pm-9:46 pm

1 stop5h 49m

$245

St. LouisJacksonville

STL - JAX

STLJAX

Lambert-St Louis

mar. 10/28

6:00 am-12:40 pm

1 stop5h 40m

Jacksonville

mar. 10/28

5:32 pm-10:04 pm

1 stop5h 32m

$247

St. LouisJacksonville

STL - JAX

STLJAX

Lambert-St Louis

jue. 11/20

9:33 am-2:51 pm

1 stop4h 18m

Jacksonville

jue. 11/27

4:01 pm-9:58 pm

1 stop6h 57m

$247

St. LouisJacksonville

STL - JAX

STLJAX

Lambert-St Louis

jue. 11/20

5:00 am-11:42 am

1 stop5h 42m

Jacksonville

jue. 11/27

6:45 am-4:25 pm

2 stops10h 40m

$253

St. LouisJacksonville

STL - JAX

STLJAX

Lambert-St Louis

mar. 10/28

10:25 am-6:55 pm

2 stops7h 30m

Jacksonville

jue. 10/30

11:20 am-5:55 pm

2 stops7h 35m

$267

St. LouisJacksonville

STL - JAX

STLJAX

Lambert-St Louis

dom. 10/26

11:32 am-5:10 pm

1 stop4h 38m

Jacksonville

dom. 11/2

12:03 pm-9:07 am

2 stops46h 04m

$268

St. LouisJacksonville

STL - JAX

STLJAX

Lambert-St Louis

jue. 12/4

6:10 pm-9:05 pm

Nonstop1h 55m

Jacksonville

dom. 12/7

7:10 pm-8:30 pm

Nonstop2h 20m

$277

SpringfieldJacksonville

SGF - JAX

SGFJAX

Springfield-Branson

sáb. 2/21

1:00 pm-8:38 pm

1 stop6h 38m

Jacksonville

mié. 2/25

5:30 am-11:14 am

1 stop6h 44m

$280

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/5

Showing 1-10 of 55 results
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Best time to book a flight from Missouri to Jacksonville

Have a flexible travel schedule? Discover the best time to fly to Jacksonville from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Jacksonville

What is the cheapest month to book a flight from Missouri to Jacksonville?

Currently, February is the cheapest month in which you can book a flight from Missouri to Jacksonville (average of $167). Flying from Missouri to Jacksonville in December is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to JAX?

Find hourly flight availability from Missouri to Jacksonville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated octubre 6, 2025.

It’s optimal to fly from Missouri to Jacksonville in the evening. By choosing this option you can save up to 41% on the cost of your flight, compared to a flight in the morning.

What is the cheapest day to fly from Missouri to Jacksonville?

Use this chart to determine the cheapest time to fly round-trip from Missouri to Jacksonville. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Missouri to Jacksonville flight should consider departing on Wednesday evenings when fares are most often at their lowest. Tuesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Jacksonville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Jacksonville from Missouri?

    Most people fly into Jacksonville (JAX) if they book a flight to Jacksonville from Missouri. Jacksonville is conveniently located just 11.2 mi from Jacksonville’s city center.

  • How popular is this Missouri to Jacksonville flight route?

    This flight path from Missouri to Jacksonville was viewed by 6 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Missouri to Jacksonville?

    Departing from Missouri to Jacksonville will take you 1h 55m. The distance between Missouri and Jacksonville is about 753 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Missouri to Jacksonville one-way?

    To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $114. Southwest flights start at $119 while deals on Delta start at $126 one-way.

  • What are the most popular routes from Missouri to Jacksonville?

    When deciding which route to take from Missouri to Jacksonville consider Kansas City - Jacksonville, Lambert-St Louis - Jacksonville or Springfield-Branson - Jacksonville as they are the most popular.

  • What are the cheapest flights from Missouri to Jacksonville?

    On average you can expect to pay $232 for a flight from Missouri to Jacksonville. The cheapest flight overall is $94 while the most popular route, (Kansas City - Jacksonville) is currently priced at $260.

  • Can I find deals for flights from Missouri to Jacksonville that include hotel bookings?

    Yes. In addition to deals on Missouri to Jacksonville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Jacksonville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Jacksonville.

  • Can I find deals for business class flights from Missouri to Jacksonville?

    Yes. Cheapflights offers flight deals from Missouri to Jacksonville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Jacksonville?

    Currently, February is the cheapest month in which you can book a flight from Missouri to Jacksonville (average of $167). Flying from Missouri to Jacksonville in December is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Jacksonville?

Book flights to Jacksonville if you plan to visit one of these locations
Jacksonville Beach
Orange Park
Fernandina Beach
Kingsland
Waycross

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See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Missouri to Jacksonville

Discover the top 4 airlines that operate flights from Missouri to Jacksonville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$206Average$349FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$211Average$349FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$214Average$349FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$278Average$368FlexibilityNo cancel feeOn-time69%

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