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$65+ Cheap flights from Missouri to Jacksonville (JAX)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/18. Fares are subject to change and may not be available on all flights or dates of travel.
STL — JAX
Mar 11 — Mar 181
Wed 3/11
Wed 3/18
1 adult, Economy
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Cheap flight deals from Missouri to Jacksonville

Cheapest flights from Missouri to Jacksonville
Explore the most affordable flight options available from Missouri to Jacksonville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 9, 2026.

This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1111:32 am
STL
-
JAX
1 stop7h 01m
Frontier
Sun 3/154:29 pm
JAX
-
STL
1 stop22h 05m
Frontier
Deal found 2/7$132
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/61:09 pm
STL
-
JAX
1 stop4h 30m
Frontier
Sun 3/84:39 pm
JAX
-
STL
1 stop21h 40m
Frontier
Deal found 2/8$141
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/104:51 pm
STL
-
JAX
2 stops25h 42m
Frontier
Sun 3/154:29 pm
JAX
-
STL
1 stop22h 05m
Frontier
Deal found 2/7$180
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/2310:55 am
MCI
-
JAX
1 stop6h 44m
Frontier
Mon 3/27:29 pm
JAX
-
MCI
2 stops45h 15m
Frontier
Deal found 2/7$187
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/2310:55 am
MCI
-
JAX
1 stop6h 44m
Frontier
Fri 2/278:12 pm
JAX
-
MCI
2 stops24h 34m
Frontier
Deal found 2/7$194
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/78:12 pm
STL
-
JAX
2 stops17h 21m
Frontier
Thu 3/124:29 pm
JAX
-
STL
1 stop22h 05m
Frontier
Deal found 2/8$200
This Kiwi.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/104:24 pm
MCI
-
JAX
2 stops26h 09m
Multiple Airlines
Sun 3/154:29 pm
JAX
-
MCI
1 stop25h 56m
Multiple Airlines
Deal found 2/6$203
This Kiwi.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/208:20 pm
STL
-
JAX
1 stop21h 21m
Multiple Airlines
Thu 2/265:51 pm
JAX
-
STL
2 stops38h 00m
Multiple Airlines
Deal found 2/6$207
This Kiwi.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/1610:55 am
MCI
-
JAX
1 stop7h 06m
Multiple Airlines
Fri 2/208:12 pm
JAX
-
MCI
2 stops39h 18m
Multiple Airlines
Deal found 2/6$210
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/244:51 pm
STL
-
JAX
2 stops25h 42m
Frontier
Mon 3/308:18 pm
JAX
-
STL
1 stop15h 14m
Frontier
Deal found 2/8$211
This Kiwi.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1811:45 am
MCI
-
JAX
1 stop6h 48m
Multiple Airlines
Mon 3/235:58 pm
JAX
-
MCI
2 stops42h 31m
Multiple Airlines
Deal found 2/6$214
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/61:09 pm
STL
-
JAX
1 stop4h 30m
Multiple Airlines
Sun 3/85:51 pm
JAX
-
STL
2 stops20h 28m
Multiple Airlines
Deal found 2/8$218

Find flight deals from Missouri to Jacksonville

Keep the following information in mind while searching for Missouri to Jacksonville flight deals. Data was last updated February 9, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$132
(Kiwi.com)

One-way from

$65
(WAYA)

Popular in

November

Cheapest in

October

Average price

$350

Good round-trip deal

$324 or less
Provider with most accurate pricing for Lambert-St Louis-Jacksonville flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Jacksonville flights.
Search Deals
From Missouri to Jacksonville
Search Deals
One-way flight from Missouri to Jacksonville
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($16 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals
Price to beat on a round-trip flight from Missouri to Jacksonville.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Jacksonville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 9, 2026.
Use the filters below to find and compare flights from Missouri to Jacksonville that are best for you.

Fly from

Missouri

Fly to

Jacksonville

Route

Depart

Return

Price

SpringfieldJacksonville

SGF - JAX

SGFJAX

Springfield-Branson

Wed 4/29

3:46 pm-10:50 pm

1 stop6h 04m

Jacksonville

Sat 5/2

5:39 pm-9:07 pm

1 stop4h 28m

$241

SpringfieldJacksonville

SGF - JAX

SGFJAX

Springfield-Branson

Fri 3/6

6:16 pm-11:59 pm

1 stop4h 43m

Jacksonville

Tue 3/10

6:02 am-11:35 am

1 stop6h 33m

$255

SpringfieldJacksonville

SGF - JAX

SGFJAX

Springfield-Branson

Wed 3/25

2:19 pm-11:12 pm

1 stop7h 53m

Jacksonville

Sat 3/28

6:02 am-11:40 am

1 stop6h 38m

$266

SpringfieldJacksonville

SGF - JAX

SGFJAX

Springfield-Branson

Thu 7/9

6:45 pm-1:08 am

1 stop5h 23m

Jacksonville

Mon 7/13

2:30 pm-6:10 pm

1 stop4h 40m

$269

St. LouisJacksonville

STL - JAX

STLJAX

Lambert-St Louis

Sat 5/2

8:13 pm-5:13 pm

1 stop20h 00m

Jacksonville

Fri 5/8

8:17 pm-6:50 am

1 stop11h 33m

$271

Kansas CityJacksonville

MCI - JAX

MCIJAX

Kansas City

Thu 4/23

2:15 pm-7:22 pm

2 stops28h 07m

Jacksonville

Sun 4/26

6:08 pm-10:18 am

1 stop17h 10m

$278

SpringfieldJacksonville

SGF - JAX

SGFJAX

Springfield-Branson

Sat 2/21

4:29 pm-11:52 pm

1 stop6h 23m

Jacksonville

Wed 2/25

4:03 pm-9:05 pm

1 stop6h 02m

$279

SpringfieldJacksonville

SGF - JAX

SGFJAX

Springfield-Branson

Fri 2/20

5:32 pm-10:58 pm

1 stop4h 26m

Jacksonville

Sat 2/21

6:30 am-12:09 pm

1 stop6h 39m

$279

SpringfieldJacksonville

SGF - JAX

SGFJAX

Springfield-Branson

Fri 2/20

4:34 pm-11:28 pm

1 stop5h 54m

Jacksonville

Sat 2/21

9:44 am-5:30 pm

2 stops8h 46m

$284

JoplinJacksonville

JLN - JAX

JLNJAX

Joplin

Sat 2/21

8:54 am-8:14 pm

2 stops10h 20m

Jacksonville

Wed 2/25

6:25 am-5:38 pm

2 stops12h 13m

$289

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/7

Showing 1-10 of 52 results
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Best time to book a flight from Missouri to Jacksonville

Have a flexible travel schedule? Discover the best time to fly to Jacksonville from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Jacksonville

What is the cheapest month to book a flight from Missouri to Jacksonville?

Currently, October is the cheapest month in which you can book a flight from Missouri to Jacksonville (average of $155). Flying from Missouri to Jacksonville in December is currently the most expensive (average of $239). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to JAX?

Find hourly flight availability from Missouri to Jacksonville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 9, 2026.

It’s optimal to fly from Missouri to Jacksonville in the evening. By choosing this option you can save up to 23% on the cost of your flight, compared to a flight at noon.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Jacksonville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Jacksonville from Missouri?

    Most people fly into Jacksonville (JAX) if they book a flight to Jacksonville from Missouri. Jacksonville is conveniently located just 11.2 mi from Jacksonville’s city center.

  • How popular is this Missouri to Jacksonville flight route?

    This flight path from Missouri to Jacksonville was viewed by 5 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Missouri to Jacksonville?

    Departing from Missouri to Jacksonville will take you 4h 43m. The distance between Missouri and Jacksonville is about 816 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Missouri to Jacksonville one-way?

    To fly one-way, consider booking your trip with Delta, which is currently one of the cheapest options available, starting at $66. American Airlines flights start at $91 while deals on Southwest start at $94 one-way.

  • What are the most popular routes from Missouri to Jacksonville?

    When deciding which route to take from Missouri to Jacksonville consider Lambert-St Louis - Jacksonville, Kansas City - Jacksonville or Springfield-Branson - Jacksonville as they are the most popular.

  • What are the cheapest flights from Missouri to Jacksonville?

    On average you can expect to pay $357 for a flight from Missouri to Jacksonville. The cheapest flight overall is $277 while the most popular route, (Lambert-St Louis - Jacksonville) is currently priced at $207.

  • Can I find deals for flights from Missouri to Jacksonville that include hotel bookings?

    Yes. In addition to deals on Missouri to Jacksonville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Jacksonville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Jacksonville.

  • Can I find deals for business class flights from Missouri to Jacksonville?

    Yes. Cheapflights offers flight deals from Missouri to Jacksonville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Jacksonville?

    Currently, October is the cheapest month in which you can book a flight from Missouri to Jacksonville (average of $155). Flying from Missouri to Jacksonville in December is currently the most expensive (average of $239). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Jacksonville?

Book flights to Jacksonville if you plan to visit one of these locations
Jacksonville Beach
Orange Park
Fernandina Beach
Kingsland
Waycross
Yulee

Browse thousands of different options on Cheapflights for your next trip

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See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Missouri to Jacksonville

Discover the top 4 airlines that operate flights from Missouri to Jacksonville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 9, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$176Average$351FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$186Average$346FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$214Average$346FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$248Average$351FlexibilityNo cancel feeOn-time69%

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