$304+ Cheap flights from Des Moines (DSM) to Italy
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/25. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — NAP
Jun 17 — Jun 241
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Italy
Keep the following information in mind while searching for Des Moines to Italy flight deals. Data was last updated June 12, 2025.
Round-trip from | $541 (United Airlines) |
|---|---|
One-way from | $304 (Mytrip) |
Popular in | June |
Cheapest in | November |
Average price | $1,649 |
Find flight deals from Des Moines to Italy
Cheapest flights from Des Moines to ItalyExplore the most affordable flight options available from Des Moines to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.
Explore the most affordable flight options available from Des Moines to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/121:00 pmDSM - MXP
2 stops38h 00mUnited Airlines
Tue 10/2112:15 pmMXP - DSM
2 stops40h 35mUnited Airlines
Deal found 6/11![United Airlines logo]()
$541
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/202:14 pmDSM - MXP
1 stop12h 11mDelta
Sat 2/286:55 amMXP - DSM
2 stops17h 01mDelta
Deal found 6/12![Delta logo]()
$555
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/203:25 pmDSM - LIN
2 stops16h 25mUnited Airlines
Sat 2/286:15 amLIN - DSM
2 stops22h 21mUnited Airlines
Deal found 6/10![United Airlines logo]()
$565
This Orbitz deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/66:36 pmDSM - MXP
3 stops32h 24mAir Canada
Tue 10/1412:15 pmMXP - DSM
2 stops31h 04mAir Canada
Deal found 6/9![Air Canada logo]()
$573
This Ovago deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/206:36 pmDSM - MXP
2 stops14h 54mLufthansa
Sat 2/288:00 amMXP - DSM
2 stops16h 33mLufthansa
Deal found 6/11![Lufthansa logo]()
$582
This KLM deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/62:14 pmDSM - MXP
1 stop12h 11mKLM
Tue 10/1411:40 amMXP - DSM
1 stop17h 43mKLM
Deal found 6/9![KLM logo]()
$589
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/78:40 amDSM - FCO
1 stop22h 50mMultiple Airlines
Sat 11/227:05 pmFCO - DSM
2 stops48h 50mMultiple Airlines
Deal found 6/11![Multiple Airlines logo]()
$618
This FlightHub deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/66:36 pmDSM - LIN
2 stops16h 14mLufthansa
Tue 10/147:00 amLIN - DSM
2 stops17h 24mLufthansa
Deal found 6/9![Lufthansa logo]()
$621
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/206:00 amDSM - MXP
1 stop22h 20mAmerican Airlines
Sat 2/2810:15 amMXP - DSM
2 stops18h 41mAmerican Airlines
Deal found 6/11![American Airlines logo]()
$639
This Booking.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/76:50 pmDSM - FCO
2 stops55h 05mAir Canada
Sat 11/2211:10 amFCO - DSM
2 stops41h 22mAir Canada
Deal found 6/11![Air Canada logo]()
$643
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/156:15 amDSM - FCO
2 stops21h 40mUnited Airlines
Fri 10/2411:30 amFCO - DSM
2 stops33h 53mUnited Airlines
Deal found 6/10![United Airlines logo]()
$666
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/235:30 pmDSM - FCO
1 stop33h 15mDelta
Tue 1/69:20 amFCO - DSM
1 stop17h 43mDelta
Deal found 6/11![Delta logo]()
$690
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Des Moines to Italy that are best for you.
Fly from
Des Moines
Fly to
Italy
Route
Depart
Return
Price
Des MoinesMilan
DSM - MXP
DSMMXP
Des Moines
Fri 7/4
3:38 pm-4:30 pm
2 stops17h 52m
Milan Malpensa
Mon 8/25
3:20 pm-9:45 pm
1 stop13h 25m
$643
Des MoinesRome
DSM - FCO
DSMFCO
Des Moines
Fri 7/4
8:35 am-2:30 pm
1 stop22h 55m
Rome Fiumicino
Thu 8/21
6:25 am-12:46 pm
2 stops37h 21m
$648
Des MoinesMilan
DSM - LIN
DSMLIN
Des Moines
Fri 7/4
11:25 am-12:00 pm
2 stops17h 35m
Milan Linate
Mon 8/25
7:00 am-9:45 pm
2 stops21h 45m
$658
Des MoinesMilan
DSM - MXP
DSMMXP
Des Moines
Mon 7/7
8:00 am-10:00 am
2 stops19h 00m
Milan Malpensa
Sun 8/24
12:15 pm-2:10 pm
2 stops32h 55m
$662
Des MoinesMilan
DSM - LIN
DSMLIN
Des Moines
Sun 8/3
6:09 pm-5:15 pm
2 stops16h 06m
Milan Linate
Tue 8/19
7:50 pm-4:35 pm
2 stops27h 45m
$703
Des MoinesMilan
DSM - MXP
DSMMXP
Des Moines
Sun 8/3
6:09 pm-6:10 pm
2 stops17h 01m
Milan Malpensa
Tue 8/19
6:50 pm-4:35 pm
2 stops28h 45m
$708
Des MoinesMilan
DSM - MXP
DSMMXP
Des Moines
Sat 7/5
11:25 am-6:55 pm
2 stops24h 30m
Milan Malpensa
Tue 8/26
6:15 am-9:45 pm
2 stops22h 30m
$714
Des MoinesVenice
DSM - VCE
DSMVCE
Des Moines
Sun 9/7
3:25 pm-9:40 am
2 stops35h 15m
Venice Marco Polo
Tue 9/16
12:20 pm-12:23 pm
2 stops31h 03m
$733
Des MoinesVenice
DSM - VCE
DSMVCE
Des Moines
Sun 8/10
6:00 am-9:55 am
1 stop20h 55m
Venice Marco Polo
Wed 9/10
12:15 pm-9:40 pm
1 stop16h 25m
$739
Des MoinesRome
DSM - FCO
DSMFCO
Des Moines
Tue 7/8
11:25 am-11:45 am
2 stops17h 20m
Rome Fiumicino
Thu 8/21
9:45 am-5:14 pm
1 stop14h 29m
$764
Showing 1-10 of 48 results
Best time to book a flight from Des Moines to Italy
Have a flexible travel schedule? Discover the best time to fly to Italy from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Italy
What is the cheapest month to book a flight from Des Moines to Italy?
Currently, January is the cheapest month in which you can book a flight from Des Moines to Italy (average of $703). Flying from Des Moines to Italy in June is currently the most expensive (average of $1,217). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DSM to IT?
Find hourly flight availability from Des Moines to Italy. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Italy as you normally would.
Rainfall in Italy by month
Plan your trip to Italy by taking into account the average rainfall totals by month.
In terms of precipitation, rainfall in Italy ranges from 0.6 - 4.4 inches per month. November is typically the wettest month, when rainfall can reach 4.4 in. June is typically the driest time to visit Italy when rainfall is around 0.6 in.
Temperature in Italy by month
Plan your trip to Italy by taking into account the average temperature totals by month.
If weather is an important factor for your trip to Italy, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 46.4 F).
Reviews of airlines servicing Italy
Get insights into the airlines that provide service to Italy. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Italy. Reviews last updated June 12, 2025.
To help decide which airline to fly from Des Moines to Italy, see what other customers have to say about Delta, KLM and Air France. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.3
Entertainment
7.9
Boarding
8.2
Overall
8.0
Comfort
7.9
Crew
8.5
Reviews
1 / 20
10.0
ExcellentKim,May 2025
PIH - SLC
Food
7.3
Entertainment
7.9
Boarding
8.2
Overall
8.0
Comfort
7.9
Crew
8.5
Reviews
1 / 20
10.0
ExcellentKim,May 2025
PIH - SLC
Food
7.3
Entertainment
7.9
Boarding
8.2
Overall
8.0
Comfort
7.9
Crew
8.5
Reviews
1 / 20
10.0
ExcellentKim,May 2025
PIH - SLC
Food
7.3
Entertainment
7.9
Boarding
8.2
Overall
8.0
Comfort
7.9
Crew
8.5
Reviews
1 / 20
10.0
ExcellentKim,May 2025
PIH - SLC
Food
7.3
Entertainment
7.9
Boarding
8.2
Overall
8.0
Comfort
7.9
Crew
8.5
Reviews
1 / 20
10.0
ExcellentKim,May 2025
PIH - SLC
Food
7.3
Entertainment
7.9
Boarding
8.2
Overall
8.0
Comfort
7.9
Crew
8.5
Reviews
1 / 20
10.0
ExcellentKim,May 2025
PIH - SLC
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Des Moines to Italy
See prices for flight routes from nearby airports that may be better suited for you.
Top 4 airlines flying from Des Moines to Italy
Discover the top 4 airlines that operate flights from Des Moines to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$631 | Average$1,002 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$663 | Average$1,076 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$668 | Average$1,089 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$671 | Average$1,226 | FlexibilityNo cancel fee | On-time71% |