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$349+ Cheap flights from Des Moines (DSM) to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/12. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — NAP
May 6 — May 131
Tue 5/6
Tue 5/13
1 adult, Economy
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Cheap flight deals from Des Moines to Italy

Keep the following information in mind while searching for Des Moines to Italy flight deals. Data was last updated May 1, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$638
(United Airlines)

One-way from

$349
(Mytrip)

Popular in

June

Cheapest in

November

Average price

$1,421
Provider with most accurate pricing for Des Moines-Rome (ROM) flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Rome (ROM) flights.
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From Des Moines to Italy
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One-way flight from Des Moines to Italy
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Highest demand for flights based on searches. 24% potential increase in price ($373 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($53 potential savings vs. average RT price).
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Average for round-trip flights in May 2025
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Find flight deals from Des Moines to Italy

Cheapest flights from Des Moines to Italy
Explore the most affordable flight options available from Des Moines to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2511:35 amDSM - FCO
2 stops38h 20mUnited Airlines
Sat 11/811:10 amFCO - DSM
2 stops30h 10mUnited Airlines
Deal found 4/30$638
This Justfly.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/142:14 pmDSM - MXP
2 stops35h 21mScandinavian Airlines
Wed 8/278:05 pmMXP - DSM
2 stops33h 17mScandinavian Airlines
Deal found 4/30$660
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/156:00 amDSM - FCO
1 stop19h 20mAmerican Airlines
Fri 10/241:10 pmFCO - DSM
1 stop14h 22mAmerican Airlines
Deal found 4/30$689
This United deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2511:35 amDSM - FCO
3 stops38h 20mMultiple Airlines
Sat 11/87:05 amFCO - DSM
2 stops17h 28mMultiple Airlines
Deal found 4/30$691
This Air Canada deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2511:35 amDSM - FCO
3 stops19h 05mAir Canada
Sat 11/87:05 amFCO - DSM
3 stops21h 31mAir Canada
Deal found 4/30$745
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/246:00 amDSM - MXP
1 stop22h 20mAmerican Airlines
Sat 10/41:20 pmMXP - DSM
1 stop14h 17mAmerican Airlines
Deal found 4/30$761
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/246:09 pmDSM - LIN
2 stops16h 06mAmerican Airlines
Sat 10/47:50 amLIN - DSM
2 stops16h 49mAmerican Airlines
Deal found 4/30$777
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1411:25 amDSM - MXP
1 stop18h 55mUnited Airlines
Wed 8/2712:15 pmMXP - DSM
2 stops32h 55mUnited Airlines
Deal found 4/30$788
This United deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/148:00 amDSM - MXP
2 stops19h 00mMultiple Airlines
Wed 8/2712:15 pmMXP - DSM
3 stops31h 08mMultiple Airlines
Deal found 4/30$794
This Iberia deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1410:03 amDSM - LIN
2 stops17h 57mIberia
Wed 8/278:20 pmLIN - DSM
2 stops31h 24mIberia
Deal found 4/30$847
This Air Canada deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2411:35 amDSM - MXP
3 stops16h 05mAir Canada
Sat 10/412:15 pmMXP - DSM
3 stops29h 24mAir Canada
Deal found 4/30$899
This Air Canada deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/241:10 pmDSM - LIN
3 stops18h 40mAir Canada
Sat 10/47:00 amLIN - DSM
3 stops21h 45mAir Canada
Deal found 4/30$907

Cheapflights Fare Finder

Customize your flight search to find flights from Des Moines to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
Use the filters below to find and compare flights from Des Moines to Italy that are best for you.

Fly from

Des Moines

Fly to

Italy

Route

Depart

Return

Price

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Sat 10/25

11:35 am-8:55 am

2 stops38h 20m

Rome Fiumicino

Sat 11/8

11:10 am-10:20 am

2 stops30h 10m

$638

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Thu 8/14

2:14 pm-8:35 am

2 stops35h 21m

Milan Malpensa

Wed 8/27

8:05 pm-10:22 pm

2 stops33h 17m

$660

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Wed 10/15

6:00 am-8:20 am

1 stop19h 20m

Rome Fiumicino

Fri 10/24

1:10 pm-8:32 pm

1 stop14h 22m

$689

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Sat 10/25

11:35 am-8:55 am

3 stops38h 20m

Rome Fiumicino

Sat 11/8

7:05 am-5:33 pm

2 stops17h 28m

$691

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Sat 10/25

11:35 am-1:40 pm

3 stops19h 05m

Rome Fiumicino

Sat 11/8

7:05 am-9:36 pm

3 stops21h 31m

$745

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Wed 9/24

6:00 am-11:20 am

1 stop22h 20m

Milan Malpensa

Sat 10/4

1:20 pm-8:37 pm

1 stop14h 17m

$761

Des MoinesMilan

DSM - LIN

DSMLIN

Des Moines

Wed 9/24

6:09 pm-5:15 pm

2 stops16h 06m

Milan Linate

Sat 10/4

7:50 am-5:39 pm

2 stops16h 49m

$777

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Thu 8/14

11:25 am-1:20 pm

1 stop18h 55m

Milan Malpensa

Wed 8/27

12:15 pm-2:10 pm

2 stops32h 55m

$788

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Thu 8/14

8:00 am-10:00 am

2 stops19h 00m

Milan Malpensa

Wed 8/27

12:15 pm-12:23 pm

3 stops31h 08m

$794

Des MoinesMilan

DSM - LIN

DSMLIN

Des Moines

Thu 8/14

10:03 am-11:00 am

2 stops17h 57m

Milan Linate

Wed 8/27

8:20 pm-8:44 pm

2 stops31h 24m

$847

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/30

Showing 1-10 of 55 results
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Best time to book a flight from Des Moines to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Italy

What is the cheapest month to book a flight from Des Moines to Italy?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Italy (average of $703). Flying from Des Moines to Italy in June is currently the most expensive (average of $1,238). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to IT?

Find hourly flight availability from Des Moines to Italy. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Italy as you normally would.

Rainfall in Italy by month

Plan your trip to Italy by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Italy ranges from 0.6 - 4.4 inches per month. November is typically the wettest month, when rainfall can reach 4.4 in. June is typically the driest time to visit Italy when rainfall is around 0.6 in.

Temperature in Italy by month

Plan your trip to Italy by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Italy, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Italy

Get insights into the airlines that provide service to Italy. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Italy. Reviews last updated May 1, 2025.
To help decide which airline to fly from Des Moines to Italy, see what other customers have to say about Delta, KLM and Air France. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,934 reviews

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,934 reviews
Delta
8.0
Very good
7,934 reviews

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
KLM
7.8
Good
1,334 reviews
Delta
8.0
Very good
7,934 reviews

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Air France
7.4
Good
1,446 reviews
Delta
8.0
Very good
7,934 reviews

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very good
7,934 reviews

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Scandinavian Airlines
7.3
Good
1,349 reviews
Delta
8.0
Very good
7,934 reviews

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Italy?

    For a flight from Des Moines to Italy, you will be flying from Des Moines. Des Moines (DSM) is just 3.6 mi from the center of the city.

  • What are the cheapest airlines to fly from Des Moines to Italy one-way?

    The cheapest airline one-way is Aer Lingus, with whom users have recently found tickets for as low as $454. However, be on the lookout for offers from Scandinavian Airlines and American Airlines, as they are both options that can get you from Des Moines to Italy for a low price.

  • What are the most popular routes from Des Moines to Italy?

    While some choose either Des Moines - Venice Marco Polo or Des Moines - Milan Linate, Des Moines - Rome Fiumicino is the most popular route from Des Moines to Italy.

  • Can I find deals for flights from Des Moines to Italy that include hotel bookings?

    Yes. In addition to deals on Des Moines to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Italy.

  • Can I find deals for business class flights from Des Moines to Italy?

    Yes. Cheapflights offers flight deals from Des Moines to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Italy?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Italy (average of $703). Flying from Des Moines to Italy in June is currently the most expensive (average of $1,238). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Italy

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Des Moines to Italy

Discover the top 4 airlines that operate flights from Des Moines to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$631Average$1,003FlexibilityNo cancel feeOn-timeN/A
KLMCheapest$668Average$1,090FlexibilityNo cancel feeOn-time75%
American AirlinesCheapest$671Average$1,217FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$688Average$1,079FlexibilityNo cancel feeOn-time69%

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