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Italy

$242+ Cheap flights from Des Moines (DSM) to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/24. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — NAP
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Des Moines to Italy

Cheapest flights from Des Moines to Italy
Explore the most affordable flight options available from Des Moines to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This Air Canada deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:46 pmDSM - MXP
2 stops32h 09mAir Canada
Wed 1/211:05 pmMXP - DSM
2 stops39h 45mAir Canada
Deal found 12/10$483
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/319:00 amDSM - MXP
2 stops24h 40mUnited Airlines
Wed 1/211:05 pmMXP - DSM
2 stops39h 45mUnited Airlines
Deal found 12/10$487
This FlightHub deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3111:35 amDSM - MXP
2 stops16h 15mLufthansa
Wed 1/216:55 amMXP - DSM
2 stops21h 55mLufthansa
Deal found 12/10$506
This KLM deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:35 amDSM - MXP
1 stop20h 30mMultiple Airlines
Wed 1/2112:35 pmMXP - DSM
2 stops16h 54mMultiple Airlines
Deal found 12/10$510
This KAYAK deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3011:35 amDSM - LIN
2 stops26h 00mLufthansa
Wed 1/216:10 amLIN - DSM
2 stops22h 40mLufthansa
Deal found 12/10$512
This Delta deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:30 pmDSM - MXP
1 stop31h 35mDelta
Wed 1/216:55 amMXP - DSM
2 stops22h 34mDelta
Deal found 12/10$515
This Air Canada deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:00 amDSM - MXP
2 stops18h 55mAir Canada
Wed 1/211:05 pmMXP - DSM
3 stops32h 28mAir Canada
Deal found 12/10$565
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:00 amDSM - FCO
2 stops17h 30mUnited Airlines
Wed 1/2111:15 amFCO - DSM
2 stops34h 18mUnited Airlines
Deal found 12/11$690
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:46 pmDSM - FCO
2 stops30h 44mUnited Airlines
Wed 1/2111:15 amFCO - DSM
2 stops34h 18mUnited Airlines
Deal found 12/10$691
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/301:30 pmDSM - FCO
2 stops21h 45mUnited Airlines
Wed 1/1411:15 amFCO - DSM
2 stops34h 18mUnited Airlines
Deal found 12/11$692
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:00 amDSM - FCO
2 stops17h 30mUnited Airlines
Thu 1/2212:50 pmFCO - DSM
2 stops40h 00mUnited Airlines
Deal found 12/11$694
This Air Canada deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:46 pmDSM - FCO
2 stops31h 34mAir Canada
Wed 1/2111:15 amFCO - DSM
2 stops41h 35mAir Canada
Deal found 12/11$695

Find flight deals from Des Moines to Italy

Keep the following information in mind while searching for Des Moines to Italy flight deals. Data was last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$444
(Ticket)

One-way from

$242
(United Airlines)

Popular in

June

Cheapest in

November

Average price

$773
Provider with most accurate pricing for Des Moines-Rome (ROM) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Rome (ROM) flights.
Search Deals
From Des Moines to Italy
Search Deals
One-way flight from Des Moines to Italy
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($293 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($55 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Des Moines to Italy that are best for you.

Fly from

Des Moines

Fly to

Italy

Route

Depart

Return

Price

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Sun 1/25

6:48 pm-9:55 am

2 stops56h 07m

Milan Malpensa

Sun 2/1

1:05 pm-2:33 pm

2 stops56h 28m

$464

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Sat 1/24

11:30 am-4:30 pm

2 stops22h 00m

Florence Peretola

Sat 1/31

8:00 am-5:47 pm

2 stops16h 47m

$469

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Sun 1/25

5:49 pm-2:55 pm

2 stops14h 06m

Milan Malpensa

Sun 2/1

11:05 am-4:28 pm

1 stop36h 23m

$473

Des MoinesVenice

DSM - VCE

DSMVCE

Des Moines

Sat 1/24

3:35 pm-12:20 pm

2 stops13h 45m

Venice Marco Polo

Sat 1/31

6:45 am-10:30 pm

2 stops22h 45m

$473

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Fri 1/23

6:48 pm-4:40 pm

2 stops14h 52m

Milan Malpensa

Fri 1/30

6:55 am-9:50 pm

2 stops21h 55m

$477

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Fri 1/23

8:00 am-4:40 pm

2 stops25h 40m

Milan Malpensa

Fri 1/30

1:05 pm-2:33 pm

2 stops32h 28m

$478

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Sun 1/25

6:48 pm-10:00 pm

2 stops20h 12m

Florence Peretola

Sun 2/1

8:00 am-9:50 pm

2 stops20h 50m

$478

Des MoinesMilan

DSM - LIN

DSMLIN

Des Moines

Mon 1/26

6:48 pm-6:50 pm

2 stops17h 02m

Milan Linate

Mon 2/2

6:15 am-5:47 pm

2 stops18h 32m

$481

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Sat 1/24

8:10 am-7:30 am

2 stops16h 20m

Milan Malpensa

Sat 1/31

9:45 am-9:50 pm

2 stops19h 05m

$482

Des MoinesVenice

DSM - VCE

DSMVCE

Des Moines

Sun 1/25

5:16 pm-5:20 pm

2 stops17h 04m

Venice Marco Polo

Sun 2/1

6:30 am-8:54 pm

2 stops21h 24m

$482

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Showing 1-10 of 60 results
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Best time to book a flight from Des Moines to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Italy

What is the cheapest month to book a flight from Des Moines to Italy?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Italy (average of $517). Flying from Des Moines to Italy in July is currently the most expensive (average of $1,065). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to IT?

Find hourly flight availability from Des Moines to Italy. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

It’s optimal to fly from Des Moines to Italy in the evening. By choosing this option you can save up to 27% on the cost of your flight, compared to a flight in the morning.

Reviews of airlines servicing Italy

Get insights into the airlines that provide service to Italy. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Italy. Reviews last updated December 12, 2025.
Peruse reviews from past customers who have flown with Delta, KLM, and United Airlines from Des Moines to Italy to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,009 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,009 reviews
Delta
7.9
Good
8,009 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
KLM
7.7
Good
1,432 reviews
Delta
7.9
Good
8,009 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,095 reviews
Delta
7.9
Good
8,009 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,048 reviews
Delta
7.9
Good
8,009 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
British Airways
6.7
Okay
7,571 reviews
Delta
7.9
Good
8,009 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Italy?

    For a flight from Des Moines to Italy, you will be flying from Des Moines. Des Moines (DSM) is just 3.6 mi from the center of the city.

  • How long is the flight from Des Moines to Italy?

    For as low as $467, Air Canada can have you in Italy from Des Moines in 16h 27m. The distance between Des Moines and Italy is about 5054 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Des Moines to Italy?

    While some choose either Des Moines - Venice Marco Polo or Des Moines - Milan Linate, Des Moines - Rome Fiumicino is the most popular route from Des Moines to Italy.

  • Can I find deals for flights from Des Moines to Italy that include hotel bookings?

    Yes. In addition to deals on Des Moines to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Italy.

  • Can I find deals for business class flights from Des Moines to Italy?

    Yes. Cheapflights offers flight deals from Des Moines to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Italy?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Italy (average of $517). Flying from Des Moines to Italy in July is currently the most expensive (average of $1,065). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Italy

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Top 4 airlines flying from Des Moines to Italy

Discover the top 4 airlines that operate flights from Des Moines to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$641Average$1,291FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$655Average$1,171FlexibilityNo cancel feeOn-time69%
KLMCheapest$680Average$1,090FlexibilityNo cancel feeOn-time75%
LufthansaCheapest$738Average$1,185FlexibilityNo cancel feeOn-time76%

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