For a smooth departure, use SFO's AirTrain to quickly navigate between terminals and reach your gate efficiently.

Most accurate provider | Mytrip 3 stars |
|---|---|
Most trusted provider | Mytrip 3 stars |
Round-trip from | $269 (United Airlines) |
One-way from | $82 (Trip.com) |
Popular in | November |
Cheapest in | September |
Average price | $369 |
Good round-trip deal | $304 or less |
Good one-way deal | $273 or less |
Fly from
Fly to
Route
Depart
Return
Price
San FranciscoIndianapolis
SFO - IND
SFOIND
San Francisco
Sat 2/7
4:39 pm-11:59 pm
Nonstop4h 20m
Indianapolis
Mon 2/9
9:58 am-12:05 pm
Nonstop5h 07m
San FranciscoIndianapolis
SFO - IND
SFOIND
San Francisco
Fri 5/8
10:47 pm-6:23 am
Nonstop4h 36m
Indianapolis
Mon 5/11
7:45 pm-12:19 am
1 stop7h 34m
San FranciscoIndianapolis
SFO - IND
SFOIND
San Francisco
Thu 3/5
11:59 pm-11:21 am
1 stop8h 22m
Indianapolis
Sun 3/8
7:15 am-9:24 am
Nonstop5h 09m
San FranciscoIndianapolis
SFO - IND
SFOIND
San Francisco
Fri 2/20
10:50 pm-11:26 am
1 stop9h 36m
Indianapolis
Mon 2/23
10:10 am-12:20 pm
Nonstop5h 10m
San FranciscoIndianapolis
SFO - IND
SFOIND
San Francisco
Fri 6/5
9:00 pm-4:33 am
Nonstop4h 33m
Indianapolis
Mon 6/8
6:50 pm-10:43 pm
1 stop6h 53m
San FranciscoIndianapolis
SFO - IND
SFOIND
San Francisco
Sun 2/8
4:41 pm-11:59 pm
Nonstop4h 18m
Indianapolis
Fri 2/20
6:00 am-10:50 am
1 stop7h 50m
San FranciscoIndianapolis
SFO - IND
SFOIND
San Francisco
Fri 4/10
11:00 pm-6:33 am
Nonstop4h 33m
Indianapolis
Fri 4/17
7:45 pm-12:19 am
1 stop7h 34m
San FranciscoIndianapolis
SFO - IND
SFOIND
San Francisco
Fri 2/6
4:41 pm-11:59 pm
Nonstop4h 18m
Indianapolis
Mon 2/9
2:00 pm-8:10 pm
1 stop9h 10m
San FranciscoIndianapolis
SFO - IND
SFOIND
San Francisco
Fri 5/8
2:25 pm-12:02 am
1 stop6h 37m
Indianapolis
Mon 5/11
11:25 am-5:26 pm
1 stop9h 01m
San FranciscoIndianapolis
SFO - IND
SFOIND
San Francisco
Wed 2/4
1:35 pm-11:30 pm
1 stop6h 55m
Indianapolis
Sat 2/7
2:00 pm-7:09 pm
1 stop8h 09m
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*1 star | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
The price you pay for your flight from San Francisco to Indianapolis may vary depending on when you book. For the best chance of a lower fare, look to book 75 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Currently, October is the cheapest month in which you can book a flight from San Francisco to Indianapolis (average of $128). Flying from San Francisco to Indianapolis in December is currently the most expensive (average of $241). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
A simple way to save on the total cost of your ticket is to fly from San Francisco to Indianapolis in the afternoon. If you’re flexible enough to do this you can expect to save up to 35% on your trip compared to booking a flight in the morning.
Travelers seeking maximum savings on their San Francisco to Indianapolis flight should consider departing on Tuesday at noon when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
About 20% of weekly flights between San Francisco and Indianapolis have experienced delays in the past year, with the average delay time being 170 minutes.
Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the evening tend to experience delays more often.
Wednesday tends to have the lowest number of delays on this route, whereas Sunday has historically faced a higher average of delays compared to other days of the week.
Over the last year, United Airlines have had the lowest number of delays on this route, with just 11% of flights being delayed.
Denver (DEN) – chosen by Cheapflights users on 67% of 1-stop itineraries from San Francisco to Indianapolis on Cheapflights.
Denver (DEN) is the most affordable 1-stop option, with an average round-trip price of $248.
Flights via Atlanta (ATL) have the shortest average one-way travel time for 1-stop routes: 6h 58m.
Flights via Atlanta (ATL) offer the fastest connection on this route, with an average layover time of 1h 01m.
Boarding
Comfort
Crew
Food
Entertainment
Overall
Reviews
William Drew,Nov 2025
SJC - HNL
Boarding
Comfort
Crew
Food
Entertainment
Overall
Reviews
William Drew,Nov 2025
SJC - HNL
Boarding
Comfort
Crew
Food
Entertainment
Overall
Reviews
William Drew,Nov 2025
SJC - HNL
Boarding
Comfort
Crew
Food
Entertainment
Overall
Reviews
William Drew,Nov 2025
SJC - HNL
Boarding
Comfort
Crew
Food
Entertainment
Overall
Reviews
William Drew,Nov 2025
SJC - HNL
Boarding
Comfort
Crew
Food
Entertainment
Overall
Reviews
William Drew,Nov 2025
SJC - HNL
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$150 | Average$247 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$198 | Average$361 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$225 | Average$288 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$269 | Average$449 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$288 | Average$433 | FlexibilityNo cancel fee | On-time63% |