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$157+ Cheap flights from Panama City, FL to Indianapolis (ECP - IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/28. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — IND
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Panama City to Indianapolis

Cheapest flights from Panama City to Indianapolis
Explore the most affordable flight options available from Panama City to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/2410:30 am
ECP
-
IND
1 stop6h 30m
Southwest
Tue 3/38:05 am
IND
-
ECP
1 stop7h 50m
Southwest
Deal found 1/27$313
This Southwest deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/24:55 pm
ECP
-
IND
Nonstop1h 55m
Southwest
Sat 5/911:15 am
IND
-
ECP
Nonstop1h 45m
Southwest
Deal found 1/28$315
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/246:30 am
ECP
-
IND
2 stops9h 19m
United Airlines
Tue 3/39:00 am
IND
-
ECP
1 stop8h 11m
United Airlines
Deal found 1/27$318
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/122:10 pm
ECP
-
IND
1 stop4h 55m
United Airlines
Wed 3/185:05 pm
IND
-
ECP
1 stop5h 52m
United Airlines
Deal found 1/27$320
This Delta deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/258:21 am
ECP
-
IND
1 stop3h 20m
Delta
Wed 4/296:00 am
IND
-
ECP
1 stop3h 35m
Delta
Deal found 1/28$324
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:30 am
ECP
-
IND
2 stops10h 23m
United Airlines
Wed 4/297:15 am
IND
-
ECP
1 stop7h 08m
United Airlines
Deal found 1/28$329
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/52:10 pm
ECP
-
IND
1 stop4h 55m
United Airlines
Mon 3/99:00 am
IND
-
ECP
1 stop5h 14m
United Airlines
Deal found 1/28$330
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/11:34 pm
ECP
-
IND
1 stop6h 26m
American Airlines
Tue 3/37:36 am
IND
-
ECP
1 stop5h 32m
American Airlines
Deal found 1/27$332
This Delta deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2911:01 am
ECP
-
IND
1 stop3h 38m
Delta
Sat 5/94:15 pm
IND
-
ECP
1 stop3h 41m
Delta
Deal found 1/28$335

Find flight deals from Panama City to Indianapolis

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$313
(Southwest)

One-way from

$157
(American Airlines)

Popular in

March

Cheapest in

September

Average price

$333
Provider with most accurate pricing for Panama City NW Florida Beaches-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City NW Florida Beaches-Indianapolis flights.
Search Deals
From Panama City NW Florida Beaches to Indianapolis
Search Deals
One-way flight from Panama City NW Florida Beaches to Indianapolis
Search Deals
Highest demand for flights based on searches. 18% potential increase in price ($92 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($24 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Panama City to Indianapolis that are best for you.

Fly from

Panama City

Fly to

Indianapolis

Route

Depart

Return

Price

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Tue 2/24

6:30 am-4:49 pm

2 stops9h 19m

Indianapolis

Tue 3/3

9:00 am-4:11 pm

1 stop8h 11m

$318

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Thu 3/12

2:10 pm-8:05 pm

1 stop4h 55m

Indianapolis

Wed 3/18

5:05 pm-9:57 pm

1 stop5h 52m

$320

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Tue 2/24

8:00 am-7:55 pm

2 stops10h 55m

Indianapolis

Tue 3/3

10:30 am-6:10 pm

2 stops8h 40m

$323

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Sat 4/25

6:30 am-5:53 pm

2 stops10h 23m

Indianapolis

Wed 4/29

7:15 am-1:23 pm

1 stop7h 08m

$329

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Thu 4/30

7:05 am-12:41 pm

1 stop4h 36m

Indianapolis

Tue 5/12

6:00 am-10:14 am

1 stop5h 14m

$335

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Sat 4/18

7:20 am-12:05 pm

1 stop3h 45m

Indianapolis

Sat 4/25

2:55 pm-6:15 pm

1 stop4h 20m

$335

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Thu 3/5

2:10 pm-8:05 pm

1 stop4h 55m

Indianapolis

Mon 3/9

11:04 am-9:57 pm

2 stops11h 53m

$336

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Sat 4/18

6:30 am-8:02 pm

2 stops12h 32m

Indianapolis

Sat 4/25

5:10 pm-9:59 pm

1 stop5h 49m

$340

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Sat 2/14

8:03 am-12:38 pm

1 stop3h 35m

Indianapolis

Sat 2/28

7:59 pm-10:39 pm

1 stop3h 40m

$343

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Fri 3/13

11:08 am-6:09 pm

1 stop6h 01m

Indianapolis

Mon 3/16

4:43 pm-7:27 pm

1 stop3h 44m

$343

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/28

Showing 1-10 of 17 results
1
2

Compare providers for flights from Panama City to Indianapolis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Indianapolis in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City, Florida-Indianapolis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-Indianapolis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Indianapolis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City, Florida-Indianapolis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Indianapolis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Indianapolis

What is the cheapest month to book a flight from Panama City, Florida to Indianapolis?

Currently, June is the cheapest month in which you can book a flight from Panama City, Florida to Indianapolis (average of $60). Flying from Panama City, Florida to Indianapolis in December is currently the most expensive (average of $135). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Indianapolis

Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated January 29, 2026.
Peruse reviews from past customers who have flown with Southwest, Delta, and American Airlines from Panama City to Indianapolis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,267 reviews

Comfort

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,267 reviews
Southwest
8.0
Very good
4,267 reviews

Comfort

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,127 reviews
Southwest
8.0
Very good
4,267 reviews

Comfort

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,206 reviews
Southwest
8.0
Very good
4,267 reviews

Comfort

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Panama City to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City, Florida to Indianapolis?

    A quick flight from Panama City, Florida to Indianapolis can take about 6h 30m. Southwest provides one of the quickest options available for as low as $313. There are 647 mi between Panama City, Florida and Indianapolis. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Panama City, Florida to Indianapolis round-trip?

    Cheapflights users have booked flights from Panama City, Florida to Indianapolis round-trip from $226. Other airlines that can offer you cheap pricing are American Airlines, from $286, and Southwest, from $333. Delta is currently priced 44% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Panama City, Florida to Indianapolis one-way?

    $113 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on United Airlines and Delta, with prices starting from $127 and $127, respectively.

  • Can I find deals for flights from Panama City to Indianapolis that include hotel bookings?

    Yes. In addition to deals on Panama City to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Indianapolis.

  • Can I find deals for business class flights from Panama City to Indianapolis?

    Yes. Cheapflights offers flight deals from Panama City to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Indianapolis?

    Currently, June is the cheapest month in which you can book a flight from Panama City, Florida to Indianapolis (average of $60). Flying from Panama City, Florida to Indianapolis in December is currently the most expensive (average of $135). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Muncie
Terre Haute
Fishers
Noblesville
Greenwood
Plainfield
Anderson
Kokomo
Mooresville
Franklin
Carmel
Crawfordsville
Bloomington

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See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Panama City to Indianapolis

Discover the top 3 airlines that operate flights from Panama City to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$226Average$368FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$286Average$406FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$333Average$409FlexibilityNo cancel feeOn-time63%

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