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$134+ Cheap flights from Panama City, FL to Indianapolis (ECP - IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/18. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — IND
oct. 17 — oct. 241
vie. 10/17
vie. 10/24
1 adult, Economy
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Cheap flight deals from Panama City to Indianapolis

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated septiembre 17, 2025.

Round-trip from

$267
(Delta)

One-way from

$134
(Delta)

Popular in

March

Cheapest in

September

Average price

$312
From Panama City NW Florida Beaches to Indianapolis
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One-way flight from Panama City NW Florida Beaches to Indianapolis
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Highest demand for flights based on searches. 16% potential increase in price ($82 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($22 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Panama City to Indianapolis

Cheapest flights from Panama City to Indianapolis
Explore the most affordable flight options available from Panama City to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 17, 2025.

This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/285:00 pmECP - IND
1 stop6h 22mDelta
mié. 11/57:00 amIND - ECP
1 stop8h 30mDelta
Deal found 9/16$267
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/161:45 pmECP - IND
1 stop8h 15mDelta
mar. 12/302:42 pmIND - ECP
1 stop6h 15mDelta
Deal found 9/15$277
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/1610:00 amECP - IND
1 stop6h 37mDelta
mié. 12/317:20 amIND - ECP
1 stop9h 41mDelta
Deal found 9/15$280
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/285:00 pmECP - IND
1 stop6h 22mDelta
lun. 11/37:00 amIND - ECP
1 stop8h 30mDelta
Deal found 9/16$281
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/1311:47 amECP - IND
1 stop5h 49mDelta
mar. 12/302:42 pmIND - ECP
1 stop6h 15mDelta
Deal found 9/15$286
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/316:00 amECP - IND
1 stop3h 33mDelta
mar. 11/47:00 amIND - ECP
1 stop6h 40mDelta
Deal found 9/16$288
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/137:02 amECP - IND
1 stop5h 13mDelta
mié. 12/317:20 amIND - ECP
1 stop9h 41mDelta
Deal found 9/15$289
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/303:33 pmECP - IND
1 stop6h 27mDelta
lun. 11/37:00 amIND - ECP
1 stop6h 40mDelta
Deal found 9/17$295
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/137:50 amECP - IND
2 stops12h 00mSouthwest
mar. 12/3011:30 amIND - ECP
2 stops7h 25mSouthwest
Deal found 9/16$297
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/316:00 amECP - IND
1 stop6h 03mDelta
lun. 11/36:00 amIND - ECP
1 stop3h 44mDelta
Deal found 9/16$302
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/306:44 amECP - IND
2 stops8h 25mAmerican Airlines
lun. 11/37:50 amIND - ECP
1 stop4h 39mAmerican Airlines
Deal found 9/17$303
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/283:33 pmECP - IND
1 stop6h 27mDelta
dom. 11/26:51 pmIND - ECP
1 stop5h 19mDelta
Deal found 9/16$323

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 17, 2025.
Use the filters below to find and compare flights from Panama City to Indianapolis that are best for you.

Fly from

Panama City

Fly to

Indianapolis

Route

Depart

Return

Price

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

mar. 10/28

5:00 pm-12:22 am

1 stop6h 22m

Indianapolis

mié. 11/5

7:00 am-2:30 pm

1 stop8h 30m

$267

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

mar. 10/7

6:00 am-10:33 am

1 stop3h 33m

Indianapolis

mar. 10/14

7:00 am-2:30 pm

1 stop8h 30m

$267

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

mié. 10/29

5:00 pm-9:43 pm

1 stop3h 43m

Indianapolis

mar. 11/4

8:05 am-12:40 pm

1 stop5h 35m

$267

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

mié. 12/17

6:00 am-1:25 pm

1 stop6h 25m

Indianapolis

mié. 12/31

7:20 am-4:01 pm

1 stop9h 41m

$280

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

mar. 12/16

5:00 pm-9:43 pm

1 stop3h 43m

Indianapolis

jue. 1/1

7:20 am-4:01 pm

1 stop9h 41m

$280

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

sáb. 12/13

12:05 pm-8:25 pm

1 stop7h 20m

Indianapolis

mar. 12/30

6:15 am-12:10 pm

1 stop6h 55m

$281

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

lun. 11/3

3:33 pm-11:00 pm

1 stop6h 27m

Indianapolis

mar. 11/4

7:00 am-12:40 pm

1 stop6h 40m

$281

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

mié. 10/29

5:00 pm-12:22 am

1 stop6h 22m

Indianapolis

lun. 11/3

6:00 am-8:44 am

1 stop3h 44m

$281

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

jue. 10/30

3:33 pm-11:00 pm

1 stop6h 27m

Indianapolis

mié. 11/5

7:00 am-2:30 pm

1 stop8h 30m

$281

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

mar. 10/28

5:00 pm-12:22 am

1 stop6h 22m

Indianapolis

lun. 11/3

7:00 am-2:30 pm

1 stop8h 30m

$281

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Showing 1-10 of 20 results
1
2

Best time to book a flight from Panama City to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Indianapolis

What is the cheapest month to book a flight from Panama City, Florida to Indianapolis?

Currently, August is the cheapest month in which you can book a flight from Panama City, Florida to Indianapolis (average of $286). Flying from Panama City, Florida to Indianapolis in March is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ECP to IND?

Find hourly flight availability from Panama City to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 17, 2025.

A simple way to save on the total cost of your ticket is to fly from Panama City, Florida to Indianapolis in the evening. If you’re flexible enough to do this you can expect to save up to 37% on your trip compared to booking a flight in the afternoon.

Reviews of airlines servicing Indianapolis

Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated septiembre 17, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and American Airlines from Panama City to Indianapolis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,242 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,961 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Panama City to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City, Florida to Indianapolis?

    A quick flight from Panama City, Florida to Indianapolis can take about 6h 22m. Delta provides one of the quickest options available for as low as $267. There are 647 mi between Panama City, Florida and Indianapolis.

  • What are the cheapest airlines flying from Panama City, Florida to Indianapolis round-trip?

    Cheapflights users have booked flights from Panama City, Florida to Indianapolis round-trip from $226. Other airlines that can offer you cheap pricing are American Airlines, from $292, and Southwest, from $333. Delta is currently priced 44% below the average price you’ll pay for this route.

  • Can I find deals for flights from Panama City to Indianapolis that include hotel bookings?

    Yes. In addition to deals on Panama City to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Indianapolis.

  • Can I find deals for business class flights from Panama City to Indianapolis?

    Yes. Cheapflights offers flight deals from Panama City to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Indianapolis?

    Currently, August is the cheapest month in which you can book a flight from Panama City, Florida to Indianapolis (average of $286). Flying from Panama City, Florida to Indianapolis in March is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Muncie
Terre Haute
Noblesville
Fishers
Anderson
Kokomo
Greenwood
Bloomington
Franklin
Plainfield
Carmel
Crawfordsville
Speedway

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Panama City to Indianapolis

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Panama City to Indianapolis

Discover the top 3 airlines that operate flights from Panama City to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$226Average$357FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$292Average$417FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$333Average$402FlexibilityNo cancel feeOn-time63%

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