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$146+ Cheap flights from Panama City, FL to Indianapolis (ECP - IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/17. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — IND
Jun 21 — Jun 281
Sun 6/21
Sun 6/28
1 adult, Economy
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Cheap flight deals from Panama City to Indianapolis

Cheapest flights from Panama City to Indianapolis
Explore the most affordable flight options available from Panama City to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 22, 2026.

This American Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/62:43 pm
ECP
-
IND
1 stop4h 32m
American Airlines
Sun 6/77:45 am
IND
-
ECP
1 stop6h 00m
American Airlines
Deal found 5/17$276
This Delta deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:00 am
ECP
-
IND
1 stop3h 32m
Delta
Mon 10/128:00 pm
IND
-
ECP
1 stop3h 47m
Delta
Deal found 5/17$291
This American Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/52:26 pm
ECP
-
IND
2 stops8h 33m
American Airlines
Sat 9/121:59 pm
IND
-
ECP
1 stop5h 51m
American Airlines
Deal found 5/22$296
This Delta deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/35:29 pm
ECP
-
IND
1 stop6h 04m
Delta
Mon 6/86:40 pm
IND
-
ECP
1 stop6h 04m
Delta
Deal found 5/18$301
This American Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/311:00 am
ECP
-
IND
2 stops6h 57m
American Airlines
Tue 6/96:11 am
IND
-
ECP
1 stop5h 17m
American Airlines
Deal found 5/20$306
This Delta deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/281:50 pm
ECP
-
IND
1 stop4h 13m
Delta
Wed 6/36:00 am
IND
-
ECP
1 stop3h 30m
Delta
Deal found 5/19$320
This Delta deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/105:07 pm
ECP
-
IND
1 stop4h 20m
Delta
Thu 7/164:33 pm
IND
-
ECP
1 stop5h 13m
Delta
Deal found 5/18$325
This Southwest deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/208:05 pm
ECP
-
IND
Nonstop1h 50m
Southwest
Tue 7/2112:25 pm
IND
-
ECP
1 stop5h 20m
Southwest
Deal found 5/19$329
This Southwest deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/68:05 pm
ECP
-
IND
Nonstop1h 50m
Southwest
Sun 6/76:05 pm
IND
-
ECP
1 stop3h 35m
Southwest
Deal found 5/17$335
This Delta deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/17:41 am
ECP
-
IND
1 stop3h 59m
Delta
Tue 7/76:38 pm
IND
-
ECP
1 stop5h 59m
Delta
Deal found 5/19$339

Find flight deals from Panama City to Indianapolis

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 22, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$276
(American Airlines)

One-way from

$126
(American Airlines)

Popular in

December

Cheapest in

September

Average price

$368

Good one-way deal

$262 or less
Provider with most accurate pricing for Panama City NW Florida Beaches-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City NW Florida Beaches-Indianapolis flights.
Search Deals
From Panama City NW Florida Beaches to Indianapolis
Search Deals
One-way flight from Panama City NW Florida Beaches to Indianapolis
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($28 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
Search Deals
Price to beat on a one-way flight from Panama City NW Florida Beaches to Indianapolis.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 22, 2026.
Use the filters below to find and compare flights from Panama City to Indianapolis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Tue 6/23

5:08 pm-12:35 am

1 stop6h 27m

Indianapolis

Tue 6/30

8:05 am-10:50 am

1 stop3h 45m

$291

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Wed 7/15

5:07 pm-12:41 am

1 stop6h 34m

Indianapolis

Thu 7/16

4:33 pm-8:46 pm

1 stop5h 13m

$291

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Thu 10/8

6:00 am-10:32 am

1 stop3h 32m

Indianapolis

Mon 10/12

8:00 pm-10:47 pm

1 stop3h 47m

$291

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Wed 6/3

5:29 pm-12:33 am

1 stop6h 04m

Indianapolis

Mon 6/8

6:40 pm-11:44 pm

1 stop6h 04m

$301
Quickest round-trip

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Sat 6/6

8:05 pm-10:55 pm

Nonstop1h 50m

Indianapolis

Sun 6/7

2:55 pm-3:45 pm

Nonstop1h 50m

$343

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Thu 6/25

6:20 pm-10:50 pm

1 stop3h 30m

Indianapolis

Sun 6/28

12:30 pm-4:20 pm

1 stop4h 50m

$345

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Thu 6/25

6:45 pm-12:35 am

1 stop4h 50m

Indianapolis

Sat 6/27

4:32 pm-8:14 am

1 stop16h 42m

$367

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Wed 6/24

2:46 pm-9:02 am

1 stop17h 16m

Indianapolis

Tue 6/30

1:46 pm-6:43 pm

1 stop5h 57m

$367

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Sun 8/2

3:05 pm-6:00 pm

Nonstop1h 55m

Indianapolis

Sat 8/8

6:50 am-9:55 am

1 stop4h 05m

$368

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Wed 6/3

2:26 pm-11:26 pm

1 stop8h 00m

Indianapolis

Sat 6/6

5:26 pm-9:58 pm

1 stop5h 32m

$381

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/22

Showing 1-10 of 21 resultsSorted by cheapest first
1
2
3

Compare providers for flights from Panama City to Indianapolis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Indianapolis in May.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City, Florida-Indianapolis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-Indianapolis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Indianapolis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City, Florida-Indianapolis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Indianapolis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Indianapolis

What is the cheapest time of day to fly from ECP to IND?

Find hourly flight availability from Panama City to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 22, 2026.

When flying from Panama City, Florida to Indianapolis, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost to fly round-trip from Panama City, Florida to Indianapolis?

Reviews of airlines servicing Indianapolis

Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated May 22, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andAmerican Airlines from Panama City to Indianapolis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
7.9
Good
4,277 reviews

Boarding

8.1

Crew

8.6

Food

7.0

Comfort

8.0

Entertainment

7.5

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Southwest
7.9
Good
4,277 reviews
Southwest
7.9
Good
4,277 reviews

Boarding

8.1

Crew

8.6

Food

7.0

Comfort

8.0

Entertainment

7.5

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Delta
7.9
Good
8,447 reviews
Southwest
7.9
Good
4,277 reviews

Boarding

8.1

Crew

8.6

Food

7.0

Comfort

8.0

Entertainment

7.5

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
American Airlines
7.1
Good
11,644 reviews
Southwest
7.9
Good
4,277 reviews

Boarding

8.1

Crew

8.6

Food

7.0

Comfort

8.0

Entertainment

7.5

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City, Florida to Indianapolis?

    A quick flight from Panama City, Florida to Indianapolis can take about 3h 32m. Delta provides one of the quickest options available for as low as $291. There are 647 mi between Panama City, Florida and Indianapolis.

  • What are the cheapest airlines flying from Panama City, Florida to Indianapolis round-trip?

    Cheapflights users have booked flights from Panama City, Florida to Indianapolis round-trip from $226. Other airlines that can offer you cheap pricing are American Airlines, from $286, and Southwest, from $290. Delta is currently priced 38% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Panama City, Florida to Indianapolis one-way?

    $128 is the cheapest one-way deal found within the past few days, from United Airlines. You may also be able to find cheap deals on Southwest and American Airlines, with prices starting from $145 and $150, respectively.

  • What are the cheapest flights from Panama City, Florida to Indianapolis?

    On average you can expect to pay $278 for a flight from Panama City, Florida to Indianapolis. The cheapest flight overall is $216 while the most popular route, (Panama City NW Florida Beaches - Indianapolis) is currently priced at $291.

  • Can I find deals for flights from Panama City to Indianapolis that include hotel bookings?

    Yes. In addition to deals on Panama City to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Indianapolis.

  • Can I find deals for business class flights from Panama City to Indianapolis?

    Yes. Cheapflights offers flight deals from Panama City to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Terre Haute
Muncie
Greenwood
Fishers
Kokomo
Plainfield
Mooresville
Anderson
Franklin
Carmel
Noblesville
Bloomington

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Top 3 airlines flying from Panama City to Indianapolis

Discover the top 3 airlines that operate flights from Panama City to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 22, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$226Average$307FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$286Average$406FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$290Average$407FlexibilityNo cancel feeOn-time63%

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