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$110+ Cheap flights from Panama City, FL to Indianapolis (ECP - IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/28. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — IND
Apr 2 — Apr 91
Thu 4/2
Thu 4/9
1 adult, Economy
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Cheap flight deals from Panama City to Indianapolis

Cheapest flights from Panama City to Indianapolis
Explore the most affordable flight options available from Panama City to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 3, 2026.

This Southwest deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/75:00 pm
ECP
-
IND
1 stop5h 55m
Southwest
Sun 5/106:35 am
IND
-
ECP
1 stop5h 40m
Southwest
Deal found 2/26$267
This American Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/710:48 am
ECP
-
IND
2 stops8h 25m
American Airlines
Sun 5/108:08 pm
IND
-
ECP
1 stop4h 38m
American Airlines
Deal found 2/26$275
This Delta deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:00 am
ECP
-
IND
1 stop5h 56m
Delta
Mon 6/86:25 pm
IND
-
ECP
1 stop5h 21m
Delta
Deal found 3/2$291
This Delta deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/166:43 pm
ECP
-
IND
1 stop4h 37m
Delta
Wed 3/186:00 am
IND
-
ECP
1 stop3h 40m
Delta
Deal found 3/2$301
This American Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/14:34 pm
ECP
-
IND
1 stop7h 08m
American Airlines
Wed 4/156:00 am
IND
-
ECP
1 stop5h 03m
American Airlines
Deal found 3/2$302
This American Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/163:00 pm
ECP
-
IND
1 stop6h 20m
American Airlines
Wed 3/185:38 pm
IND
-
ECP
2 stops7h 11m
American Airlines
Deal found 2/26$306
This American Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/14:34 pm
ECP
-
IND
1 stop7h 08m
American Airlines
Mon 4/65:38 pm
IND
-
ECP
2 stops7h 11m
American Airlines
Deal found 3/2$307
This Southwest deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/77:55 am
ECP
-
IND
1 stop5h 20m
Southwest
Tue 4/146:10 am
IND
-
ECP
2 stops9h 15m
Southwest
Deal found 2/28$308
This American Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/121:20 pm
ECP
-
IND
1 stop8h 00m
American Airlines
Thu 3/198:04 pm
IND
-
ECP
1 stop4h 45m
American Airlines
Deal found 2/26$310
This United Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/410:25 am
ECP
-
IND
1 stop6h 19m
United Airlines
Sat 7/115:26 pm
IND
-
ECP
1 stop5h 32m
United Airlines
Deal found 2/26$311

Find flight deals from Panama City to Indianapolis

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 3, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$267
(Southwest)

One-way from

$110
(Delta)

Popular in

February

Cheapest in

September

Average price

$405

Good round-trip deal

$451 or less
Provider with most accurate pricing for Panama City NW Florida Beaches-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City NW Florida Beaches-Indianapolis flights.
Search Deals
From Panama City NW Florida Beaches to Indianapolis
Search Deals
One-way flight from Panama City NW Florida Beaches to Indianapolis
Search Deals
Highest demand for flights based on searches. 16% potential increase in price ($81 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($27 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals
Price to beat on a round-trip flight from Panama City NW Florida Beaches to Indianapolis.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 3, 2026.
Use the filters below to find and compare flights from Panama City to Indianapolis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Tue 4/7

6:00 am-12:39 pm

1 stop5h 39m

Indianapolis

Tue 4/14

7:05 am-10:15 am

1 stop4h 10m

$291

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Sat 4/18

6:30 am-3:53 pm

1 stop8h 23m

Indianapolis

Sat 4/25

9:29 am-4:12 pm

1 stop7h 43m

$291

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Thu 5/7

2:14 pm-8:08 pm

1 stop4h 54m

Indianapolis

Sun 5/10

7:15 am-1:18 pm

1 stop7h 03m

$291

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Wed 6/3

5:29 pm-11:36 pm

1 stop5h 07m

Indianapolis

Mon 6/8

4:15 pm-7:36 pm

1 stop4h 21m

$291

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Thu 5/7

7:10 am-4:00 pm

2 stops7h 50m

Indianapolis

Sun 5/10

6:35 am-1:15 pm

2 stops7h 40m

$301

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Mon 3/16

7:05 am-12:39 pm

1 stop4h 34m

Indianapolis

Wed 3/18

6:00 am-8:40 am

1 stop3h 40m

$301

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Sat 4/18

4:55 pm-7:50 pm

Nonstop1h 55m

Indianapolis

Sat 4/25

6:45 am-9:00 am

1 stop3h 15m

$307

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Sat 7/4

10:25 am-5:44 pm

1 stop6h 19m

Indianapolis

Sat 7/11

5:26 pm-9:58 pm

1 stop5h 32m

$311

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Wed 4/1

4:34 pm-12:42 am

1 stop7h 08m

Indianapolis

Mon 4/6

5:30 pm-11:49 pm

1 stop7h 19m

$316

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Tue 4/28

5:10 pm-12:41 am

1 stop6h 31m

$110

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/26

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

Compare providers for flights from Panama City to Indianapolis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Indianapolis in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City, Florida-Indianapolis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-Indianapolis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Indianapolis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City, Florida-Indianapolis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Indianapolis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Indianapolis

What is the cheapest month to book a flight from Panama City, Florida to Indianapolis?

Currently, June is the cheapest month in which you can book a flight from Panama City, Florida to Indianapolis (average of $60). Flying from Panama City, Florida to Indianapolis in December is currently the most expensive (average of $135). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Indianapolis

Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated March 3, 2026.
Peruse reviews from past customers who have flown with Southwest, Delta, and American Airlines from Panama City to Indianapolis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,301 reviews

Crew

8.6

Overall

8.0

Food

7.0

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Anonymous,Feb 2026

DEN - BDL

Weird they cancelled a direct and rerouted me on a connecting flight to get in 10 hours later. What was the point? Crew and flight were great, but not sure what's going on with Southwest.
Southwest
8.0
Very good
4,301 reviews
Southwest
8.0
Very good
4,301 reviews

Crew

8.6

Overall

8.0

Food

7.0

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Anonymous,Feb 2026

DEN - BDL

Weird they cancelled a direct and rerouted me on a connecting flight to get in 10 hours later. What was the point? Crew and flight were great, but not sure what's going on with Southwest.
Delta
7.9
Good
8,242 reviews
Southwest
8.0
Very good
4,301 reviews

Crew

8.6

Overall

8.0

Food

7.0

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Anonymous,Feb 2026

DEN - BDL

Weird they cancelled a direct and rerouted me on a connecting flight to get in 10 hours later. What was the point? Crew and flight were great, but not sure what's going on with Southwest.
American Airlines
7.1
Good
11,375 reviews
Southwest
8.0
Very good
4,301 reviews

Crew

8.6

Overall

8.0

Food

7.0

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Anonymous,Feb 2026

DEN - BDL

Weird they cancelled a direct and rerouted me on a connecting flight to get in 10 hours later. What was the point? Crew and flight were great, but not sure what's going on with Southwest.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City, Florida to Indianapolis?

    A quick flight from Panama City, Florida to Indianapolis can take about 5h 55m. Southwest provides one of the quickest options available for as low as $267. There are 647 mi between Panama City, Florida and Indianapolis. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Panama City, Florida to Indianapolis round-trip?

    Cheapflights users have booked flights from Panama City, Florida to Indianapolis round-trip from $226. Other airlines that can offer you cheap pricing are American Airlines, from $276, and Southwest, from $333. Delta is currently priced 44% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Panama City, Florida to Indianapolis one-way?

    $94 is the cheapest one-way deal found within the past few days, from United Airlines. You may also be able to find cheap deals on American Airlines and Delta, with prices starting from $113 and $127, respectively.

  • What are the cheapest flights from Panama City, Florida to Indianapolis?

    On average you can expect to pay $451 for a flight from Panama City, Florida to Indianapolis. The cheapest flight overall is $375 while the most popular route, (Panama City NW Florida Beaches - Indianapolis) is currently priced at $291.

  • Can I find deals for flights from Panama City to Indianapolis that include hotel bookings?

    Yes. In addition to deals on Panama City to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Indianapolis.

  • Can I find deals for business class flights from Panama City to Indianapolis?

    Yes. Cheapflights offers flight deals from Panama City to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Indianapolis?

    Currently, June is the cheapest month in which you can book a flight from Panama City, Florida to Indianapolis (average of $60). Flying from Panama City, Florida to Indianapolis in December is currently the most expensive (average of $135). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Muncie
Terre Haute
Fishers
Noblesville
Greenwood
Plainfield
Mooresville
Franklin
Anderson
Carmel
Kokomo
Crawfordsville
Bloomington

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Alternative routes for Panama City to Indianapolis

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Top 3 airlines flying from Panama City to Indianapolis

Discover the top 3 airlines that operate flights from Panama City to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 3, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$226Average$358FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$276Average$406FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$333Average$435FlexibilityNo cancel feeOn-time63%

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