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$146+ Cheap flights from Panama City, FL to Indianapolis (ECP - IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/26. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — IND
May 29 — Jun 51
Fri 5/29
Fri 6/5
1 adult, Economy
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Cheap flight deals from Panama City to Indianapolis

Cheapest flights from Panama City to Indianapolis
Explore the most affordable flight options available from Panama City to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2026.

This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/37:41 am
ECP
-
IND
1 stop4h 15m
Delta
Mon 6/88:05 am
IND
-
ECP
1 stop5h 21m
Delta
Deal found 4/24$213
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/34:16 pm
ECP
-
IND
2 stops7h 39m
American Airlines
Mon 6/87:39 pm
IND
-
ECP
1 stop5h 01m
American Airlines
Deal found 4/28$296
This Southwest deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/93:05 pm
ECP
-
IND
1 stop4h 15m
Southwest
Sat 5/162:55 pm
IND
-
ECP
1 stop4h 20m
Southwest
Deal found 4/25$301
This American Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/91:06 pm
ECP
-
IND
1 stop4h 57m
American Airlines
Sat 5/163:54 pm
IND
-
ECP
2 stops8h 52m
American Airlines
Deal found 4/25$306
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1211:43 am
ECP
-
IND
2 stops8h 30m
American Airlines
Sat 5/163:54 pm
IND
-
ECP
2 stops8h 52m
American Airlines
Deal found 4/27$311
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:00 am
ECP
-
IND
1 stop3h 30m
Delta
Thu 9/248:00 pm
IND
-
ECP
1 stop3h 46m
Delta
Deal found 4/26$325
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/167:50 am
ECP
-
IND
1 stop3h 30m
Southwest
Mon 7/206:45 am
IND
-
ECP
2 stops8h 30m
Southwest
Deal found 4/28$335
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/274:16 pm
ECP
-
IND
2 stops7h 39m
American Airlines
Wed 6/38:50 am
IND
-
ECP
2 stops7h 56m
American Airlines
Deal found 4/28$338
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/166:20 pm
ECP
-
IND
1 stop3h 30m
Southwest
Sun 7/192:55 pm
IND
-
ECP
Nonstop1h 50m
Southwest
Deal found 4/26$345
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/214:16 pm
ECP
-
IND
1 stop6h 51m
American Airlines
Tue 5/265:30 pm
IND
-
ECP
1 stop7h 10m
American Airlines
Deal found 4/27$350

Find flight deals from Panama City to Indianapolis

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$213
(Delta)

One-way from

$101
(Delta)

Popular in

April

Cheapest in

September

Average price

$498
Provider with most accurate pricing for Panama City NW Florida Beaches-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City NW Florida Beaches-Indianapolis flights.
Search Deals
From Panama City NW Florida Beaches to Indianapolis
Search Deals
One-way flight from Panama City NW Florida Beaches to Indianapolis
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($26 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
Use the filters below to find and compare flights from Panama City to Indianapolis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Wed 6/3

5:29 pm-11:26 pm

1 stop4h 57m

Indianapolis

Mon 6/8

8:05 am-12:26 pm

1 stop5h 21m

$291

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Wed 6/3

2:26 pm-11:26 pm

1 stop8h 00m

Indianapolis

Wed 6/10

9:20 am-1:21 pm

1 stop5h 01m

$291

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Thu 8/6

7:05 am-12:40 pm

1 stop4h 35m

Indianapolis

Tue 8/11

1:30 pm-6:45 pm

1 stop6h 15m

$291

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Tue 9/22

6:00 am-10:30 am

1 stop3h 30m

Indianapolis

Mon 9/28

7:20 am-2:36 pm

1 stop8h 16m

$291

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Sat 6/27

7:41 am-3:20 pm

1 stop6h 39m

Indianapolis

Tue 6/30

8:05 am-10:50 am

1 stop3h 45m

$291

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Wed 6/17

1:31 pm-6:54 pm

1 stop4h 23m

Indianapolis

Sun 6/21

7:59 pm-11:44 pm

1 stop4h 45m

$291

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Sat 9/5

6:00 am-10:30 am

1 stop3h 30m

Indianapolis

Sat 9/12

7:20 am-2:36 pm

1 stop8h 16m

$291

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Sat 6/13

4:00 pm-10:58 pm

1 stop5h 58m

Indianapolis

Sat 6/20

6:40 pm-11:07 pm

1 stop5h 27m

$291

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Thu 9/24

3:20 pm-9:55 pm

1 stop5h 35m

Indianapolis

Sat 9/26

6:25 pm-10:46 pm

1 stop5h 21m

$291

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Thu 10/8

7:05 pm-12:32 am

1 stop4h 27m

Indianapolis

Mon 10/12

8:00 pm-10:47 pm

1 stop3h 47m

$291

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/24

Showing 1-10 of 23 resultsSorted by cheapest first
1
2
3

Compare providers for flights from Panama City to Indianapolis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Indianapolis in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City, Florida-Indianapolis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-Indianapolis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Indianapolis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City, Florida-Indianapolis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Indianapolis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Indianapolis

What is the cheapest time of day to fly from ECP to IND?

Find hourly flight availability from Panama City to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 29, 2026.

When flying from Panama City, Florida to Indianapolis, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost to fly round-trip from Panama City, Florida to Indianapolis?

Reviews of airlines servicing Indianapolis

Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated April 29, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andAmerican Airlines from Panama City to Indianapolis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,314 reviews

Comfort

8.0

Entertainment

7.5

Food

7.0

Overall

8.0

Crew

8.6

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Southwest
8.0
Very good
4,314 reviews
Southwest
8.0
Very good
4,314 reviews

Comfort

8.0

Entertainment

7.5

Food

7.0

Overall

8.0

Crew

8.6

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Delta
7.9
Good
8,465 reviews
Southwest
8.0
Very good
4,314 reviews

Comfort

8.0

Entertainment

7.5

Food

7.0

Overall

8.0

Crew

8.6

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
American Airlines
7.1
Good
11,678 reviews
Southwest
8.0
Very good
4,314 reviews

Comfort

8.0

Entertainment

7.5

Food

7.0

Overall

8.0

Crew

8.6

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City, Florida to Indianapolis?

    A quick flight from Panama City, Florida to Indianapolis can take about 4h 15m. Delta provides one of the quickest options available for as low as $213. There are 647 mi between Panama City, Florida and Indianapolis. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Panama City, Florida to Indianapolis round-trip?

    Cheapflights users have booked flights from Panama City, Florida to Indianapolis round-trip from $226. Other airlines that can offer you cheap pricing are American Airlines, from $276, and Southwest, from $324. Delta is currently priced 39% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Panama City, Florida to Indianapolis one-way?

    $128 is the cheapest one-way deal found within the past few days, from United Airlines. You may also be able to find cheap deals on American Airlines and Southwest, with prices starting from $142 and $145, respectively.

  • Can I find deals for flights from Panama City to Indianapolis that include hotel bookings?

    Yes. In addition to deals on Panama City to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Indianapolis.

  • Can I find deals for business class flights from Panama City to Indianapolis?

    Yes. Cheapflights offers flight deals from Panama City to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Terre Haute
Muncie
Greenwood
Fishers
Kokomo
Plainfield
Mooresville
Anderson
Franklin
Carmel
Noblesville
Bloomington

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Top 3 airlines flying from Panama City to Indianapolis

Discover the top 3 airlines that operate flights from Panama City to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$226Average$318FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$276Average$406FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$324Average$451FlexibilityNo cancel feeOn-time63%

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