What are the cheapest airlines flying from Panama City, Florida to Indianapolis round-trip?

Cheapflights users have booked flights from Panama City, Florida to Indianapolis round-trip from $252. Other airlines that can offer you cheap pricing are Delta, from $294, and United Airlines, from $323. American Airlines is currently priced 30% below the average price you’ll pay for this route.

What are the cheapest airlines to fly from Panama City, Florida to Indianapolis one-way?

$125 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on Delta and United Airlines, with prices starting from $128 and $133, respectively.

What is the cheapest day to fly from Panama City, Florida to Indianapolis?

Travelers seeking maximum savings on their Panama City, Florida to Indianapolis flight should consider departing on Monday afternoons when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

What are the cheapest flights from Panama City, Florida to Indianapolis?

On average you can expect to pay $358 for a flight from Panama City, Florida to Indianapolis. The cheapest flight overall is $153 while the most popular route, (Panama City NW Florida Beaches - Indianapolis) is currently priced at $255.

What are the most popular airlines that fly from Panama City, Florida to Indianapolis?

American Airlines, Delta and Southwest are the most popular airlines when flying from Panama City, Florida to Indianapolis.

What is the cheapest day to fly round-trip from Panama City, Florida to Indianapolis?

Users have found that leaving on a Monday can be a cost-effective option. It’s possible to save up to 125% on your flight compared to booking on days when demand is much higher.

What is the cheapest month to fly from Panama City, Florida to Indianapolis?

Due to multiple factors, expect to potentially pay more when booking in March. For low rates, July can be a great choice for travel to Indianapolis. Flights to Indianapolis from Panama City, Florida in July are about $363 on average during July, but can be found for as low as $180.

Most accurate provider : When it comes to deals on Panama City, Florida-Indianapolis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-Indianapolis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Indianapolis flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Panama City, Florida-Indianapolis flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Indianapolis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Panama City to Indianapolis that include hotel bookings?

Yes. In addition to deals on Panama City to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Panama City to Indianapolis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Indianapolis.

Can I find deals for business class flights from Panama City to Indianapolis?

Yes. Cheapflights offers flight deals from Panama City to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$125+ Flights from Panama City, FL to Indianapolis

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1. Tell us where you want to go

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2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Panama City NW Florida Beaches to Indianapolis are usually found in July or June, booked 33 days in advance, depart on a Tuesday or Wednesday and return on a Tuesday

Cheap flight deals from Panama City to Indianapolis

Most accurate provider	FlightHub 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$252 (American Airlines)
One-way from	$125 (American Airlines)
Popular in	March
Cheapest in	July
Average price	$363
Good round-trip deal	$398 or less
Good one-way deal	$179 or less

Provider with most accurate pricing for Panama City NW Florida Beaches-Indianapolis flight deals.

Search Deals

Provider most trusted by Cheapflights users for Panama City NW Florida Beaches-Indianapolis flights.

Search Deals

From Panama City NW Florida Beaches to Indianapolis

Search Deals

One-way flight from Panama City NW Florida Beaches to Indianapolis

Search Deals

Highest demand for flights based on searches. 21% potential increase in price ($97 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 7% potential price decrease ($26 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in May 2025

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Price to beat on a round-trip flight from Panama City NW Florida Beaches to Indianapolis.

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Price to beat on a one-way flight from Panama City NW Florida Beaches to Indianapolis.

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Find flight deals from Panama City to Indianapolis

Cheapest flights from Panama City to Indianapolis
Explore the most affordable flight options available from Panama City to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on mayo 1, 2025.

mié. 7/165:17 pmECP - IND

1 stop6h 17mAmerican Airlines

mié. 8/137:09 amIND - ECP

1 stop6h 38mAmerican Airlines

Deal found 4/30

$252

vie. 9/51:30 pmECP - IND

1 stop3h 47mDelta

dom. 9/78:00 amIND - ECP

1 stop7h 27mDelta

Deal found 4/29

$294

dom. 6/15:07 pmECP - IND

1 stop5h 37mUnited Airlines

sáb. 6/77:00 amIND - ECP

1 stop5h 32mUnited Airlines

Deal found 4/30

$323

vie. 9/57:25 amECP - IND

2 stops8h 45mSouthwest

dom. 9/75:35 amIND - ECP

2 stops11h 15mSouthwest

Deal found 4/29

$347

Best flights from Panama City to Indianapolis
Discover carefully curated flight deals from Panama City to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated mayo 1, 2025.

mié. 7/165:17 pmECP - IND

1 stop6h 17mAmerican Airlines

mié. 8/137:09 amIND - ECP

1 stop6h 38mAmerican Airlines

Deal found 4/30

$252

vie. 9/51:30 pmECP - IND

1 stop3h 47mDelta

dom. 9/78:00 amIND - ECP

1 stop7h 27mDelta

Deal found 4/29

$294

dom. 6/15:07 pmECP - IND

1 stop5h 37mUnited Airlines

sáb. 6/77:00 amIND - ECP

1 stop5h 32mUnited Airlines

Deal found 4/30

$323

vie. 9/57:25 amECP - IND

2 stops8h 45mSouthwest

dom. 9/75:35 amIND - ECP

2 stops11h 15mSouthwest

Deal found 4/29

$347

Last-minute flights from Panama City to Indianapolis
Discover last-minute flight deals from Panama City to Indianapolis. Data last updated mayo 1, 2025 and is based on user searches.

mié. 5/711:25 amECP - IND

1 stop3h 55mSouthwest

dom. 5/1111:55 amIND - ECP

Nonstop1h 45mSouthwest

Deal found 4/30

$497

jue. 5/155:01 pmECP - IND

1 stop5h 54mUnited Airlines

lun. 5/197:00 amIND - ECP

1 stop6h 25mUnited Airlines

Deal found 4/30

$417

vie. 5/3010:22 amECP - IND

1 stop6h 59mAmerican Airlines

vie. 6/65:36 pmIND - ECP

1 stop7h 13mAmerican Airlines

Deal found 4/30

$291

vie. 5/306:59 pmECP - IND

1 stop4h 16mDelta

vie. 6/67:59 pmIND - ECP

1 stop4h 05mDelta

Deal found 4/29

$333

vie. 5/309:20 amECP - IND

2 stops9h 35mSouthwest

vie. 6/63:05 pmIND - ECP

2 stops8h 55mSouthwest

Deal found 4/30

$408

One-way flights from Panama City to Indianapolis
Search for one-way flight options from Panama City to Indianapolis. Find affordable one-way fares based on user searches. Data last updated mayo 1, 2025.

vie. 5/3012:25 pmECP - IND

1 stop4h 56mAmerican Airlines

Deal found 4/29

$125

mié. 7/27:25 amECP - IND

1 stop4h 18mDelta

Deal found 4/30

$128

mar. 6/106:30 amECP - IND

2 stops8h 09mUnited Airlines

Deal found 4/30

$133

jue. 6/57:00 amECP - IND

2 stops10h 50mSouthwest

Deal found 4/30

$154

Cheapflights Fare Finder

Use the filters below to find and compare flights from Panama City to Indianapolis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

mié. 7/16

5:17 pm-12:34 am

1 stop6h 17m

Indianapolis

mié. 8/13

7:09 am-12:47 pm

1 stop6h 38m

$252

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

vie. 9/5

1:30 pm-6:17 pm

1 stop3h 47m

Indianapolis

dom. 9/7

8:00 am-2:27 pm

1 stop7h 27m

$294

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

dom. 6/1

5:07 pm-11:44 pm

1 stop5h 37m

Indianapolis

sáb. 6/7

7:00 am-11:32 am

1 stop5h 32m

$323

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

vie. 9/5

7:25 am-5:10 pm

2 stops8h 45m

Indianapolis

dom. 9/7

5:35 am-3:50 pm

2 stops11h 15m

$347

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

vie. 5/30

12:25 pm-6:21 pm

1 stop4h 56m

$125

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

mar. 5/27

3:18 pm-10:42 pm

1 stop6h 24m

$128

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

mar. 6/10

6:30 am-3:39 pm

2 stops8h 09m

$133

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

jue. 6/5

7:00 am-6:50 pm

2 stops10h 50m

$154

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Compare providers for flights from Panama City to Indianapolis

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Indianapolis in May.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy1 star	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*2 stars
eDreams	Price Accuracy3 stars	Trust Score*3 stars
Priceline	Price Accuracy2 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Panama City, Florida-Indianapolis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-Indianapolis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Indianapolis flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Panama City, Florida-Indianapolis flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Indianapolis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Panama City with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Indianapolis

What is the cheapest month to book a flight from Panama City, Florida to Indianapolis?

Currently, August is the cheapest month in which you can book a flight from Panama City, Florida to Indianapolis (average of $297). Flying from Panama City, Florida to Indianapolis in March is currently the most expensive (average of $361). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ECP to IND?

A simple way to save on the total cost of your ticket is to fly from Panama City, Florida to Indianapolis in the afternoon. If you’re flexible enough to do this you can expect to save up to 37% on your trip compared to booking a flight at noon.

Rainfall in Indianapolis by month

In terms of precipitation, rainfall in Indianapolis ranges from 2.3 - 5.1 inches per month. May is typically the wettest month, when rainfall can reach 5.1 in. February is typically the driest time to visit Indianapolis when rainfall is around 2.3 in.

Temperature in Indianapolis by month

If weather is an important factor for your trip to Indianapolis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Indianapolis

Southwest

8.0

Very good

4,294 reviews

Reviews

1 / 20

10.0

Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Southwest

8.0

Very good

4,294 reviews

Southwest

8.0

Very good

4,294 reviews

Reviews

1 / 20

10.0

Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Delta

8.0

Very good

7,934 reviews

Southwest

8.0

Very good

4,294 reviews

Reviews

1 / 20

10.0

Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

United Airlines

7.4

Good

8,696 reviews

Southwest

8.0

Very good

4,294 reviews

Reviews

1 / 20

10.0

Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

American Airlines

7.2

Good

10,000 reviews

Southwest

8.0

Very good

4,294 reviews

Reviews

1 / 20

10.0

Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Related info for your journey

What are the cheapest airlines flying from Panama City, Florida to Indianapolis round-trip?
Cheapflights users have booked flights from Panama City, Florida to Indianapolis round-trip from $252. Other airlines that can offer you cheap pricing are Delta, from $294, and United Airlines, from $323. American Airlines is currently priced 30% below the average price you’ll pay for this route.
What are the cheapest airlines to fly from Panama City, Florida to Indianapolis one-way?
$125 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on Delta and United Airlines, with prices starting from $128 and $133, respectively.
What are the cheapest flights from Panama City, Florida to Indianapolis?
On average you can expect to pay $358 for a flight from Panama City, Florida to Indianapolis. The cheapest flight overall is $153 while the most popular route, (Panama City NW Florida Beaches - Indianapolis) is currently priced at $255.
Can I find deals for flights from Panama City to Indianapolis that include hotel bookings?
Yes. In addition to deals on Panama City to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Panama City to Indianapolis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Indianapolis.
Can I find deals for business class flights from Panama City to Indianapolis?
Yes. Cheapflights offers flight deals from Panama City to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Panama City, Florida to Indianapolis?
Currently, August is the cheapest month in which you can book a flight from Panama City, Florida to Indianapolis (average of $297). Flying from Panama City, Florida to Indianapolis in March is currently the most expensive (average of $361). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Greenwood

Bloomington

Terre Haute

Noblesville

Muncie

Fishers

Anderson

Carmel

Kokomo

Franklin

Plainfield

Crawfordsville

Shelbyville

Speedway

Browse thousands of different options on Cheapflights for your next trip

Top 3 airlines flying from Panama City to Indianapolis

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$162	Average$331	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$227	Average$321	FlexibilityNo cancel fee	On-timeN/A
Southwest	Cheapest$328	Average$408	FlexibilityNo cancel fee	On-time63%

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$125+ Cheap flights from Panama City, FL to Indianapolis (ECP - IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/30. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Panama City to Indianapolis with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Panama City NW Florida Beaches to Indianapolis are usually found in July or June, booked 33 days in advance, depart on a Tuesday or Wednesday and return on a Tuesday

Cheap flight deals from Panama City to Indianapolis

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Find flight deals from Panama City to Indianapolis

Cheapest flights from Panama City to IndianapolisExplore the most affordable flight options available from Panama City to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on mayo 1, 2025.

Explore the most affordable flight options available from Panama City to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on mayo 1, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Panama City to Indianapolis that are best for you.

Compare providers for flights from Panama City to Indianapolis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Indianapolis in May.

Best time to book a flight from Panama City to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Panama City with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Indianapolis

What is the cheapest month to book a flight from Panama City, Florida to Indianapolis?

What is the cheapest time of day to fly from ECP to IND?

Find hourly flight availability from Panama City to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated mayo 1, 2025.

Rainfall in Indianapolis by month

Plan your trip to Indianapolis by taking into account the average rainfall totals by month.

Temperature in Indianapolis by month

Plan your trip to Indianapolis by taking into account the average temperature totals by month.

Reviews of airlines servicing Indianapolis

Related info for your journey

Find useful and relevant information for your journey from Panama City to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Panama City, Florida to Indianapolis round-trip?

What are the cheapest airlines to fly from Panama City, Florida to Indianapolis one-way?

What are the cheapest flights from Panama City, Florida to Indianapolis?

Can I find deals for flights from Panama City to Indianapolis that include hotel bookings?

How can I find direct flights from Panama City to Indianapolis?

Can I find deals for business class flights from Panama City to Indianapolis?

What is the cheapest month to book a flight from Panama City, Florida to Indianapolis?

Traveling to a place near Panama City?

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Alternative routes for Panama City to Indianapolis

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Top 3 airlines flying from Panama City to Indianapolis

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Cheapest flights from Panama City to Indianapolis
Explore the most affordable flight options available from Panama City to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on mayo 1, 2025.