HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Indianapolis

$146+ Cheap flights from Panama City, FL to Indianapolis (ECP - IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/11. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — IND
May 15 — May 221
Fri 5/15
Fri 5/22
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Panama City to Indianapolis with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Panama City to Indianapolis

Cheapest flights from Panama City to Indianapolis
Explore the most affordable flight options available from Panama City to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 15, 2026.

This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/57:10 am
ECP
-
IND
1 stop4h 53m
American Airlines
Sat 9/121:59 pm
IND
-
ECP
1 stop5h 51m
American Airlines
Deal found 4/14$290
This Delta deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:00 am
ECP
-
IND
1 stop5h 56m
Delta
Mon 6/86:38 pm
IND
-
ECP
1 stop6h 06m
Delta
Deal found 4/13$291
This Southwest deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/27:20 am
ECP
-
IND
1 stop3h 45m
Southwest
Sat 5/162:55 pm
IND
-
ECP
1 stop4h 20m
Southwest
Deal found 4/12$296
This American Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/34:16 pm
ECP
-
IND
2 stops7h 39m
American Airlines
Mon 6/87:38 pm
IND
-
ECP
1 stop5h 02m
American Airlines
Deal found 4/13$298
This United Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/282:19 pm
ECP
-
IND
1 stop4h 43m
United Airlines
Sat 5/26:00 am
IND
-
ECP
1 stop4h 44m
United Airlines
Deal found 4/13$301
This American Airlines deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:45 pm
ECP
-
IND
1 stop4h 22m
American Airlines
Tue 5/265:30 pm
IND
-
ECP
1 stop7h 10m
American Airlines
Deal found 4/11$302
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/233:22 pm
ECP
-
IND
1 stop7h 37m
American Airlines
Tue 5/265:30 pm
IND
-
ECP
1 stop7h 10m
American Airlines
Deal found 4/14$304
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/91:06 pm
ECP
-
IND
1 stop7h 18m
American Airlines
Sat 5/165:33 pm
IND
-
ECP
2 stops7h 13m
American Airlines
Deal found 4/14$305
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3010:48 am
ECP
-
IND
2 stops9h 36m
American Airlines
Sun 5/37:13 am
IND
-
ECP
1 stop6h 25m
American Airlines
Deal found 4/15$306
This Southwest deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/94:55 pm
ECP
-
IND
Nonstop1h 55m
Southwest
Sat 5/162:55 pm
IND
-
ECP
1 stop4h 20m
Southwest
Deal found 4/14$317

Find flight deals from Panama City to Indianapolis

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 15, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$290
(American Airlines)

One-way from

$146
(Delta)

Popular in

December

Cheapest in

September

Average price

$464
Provider with most accurate pricing for Panama City NW Florida Beaches-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City NW Florida Beaches-Indianapolis flights.
Search Deals
From Panama City NW Florida Beaches to Indianapolis
Search Deals
One-way flight from Panama City NW Florida Beaches to Indianapolis
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($22 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 15, 2026.
Use the filters below to find and compare flights from Panama City to Indianapolis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Wed 6/3

5:29 pm-11:26 pm

1 stop4h 57m

Indianapolis

Mon 6/8

4:33 pm-8:47 pm

1 stop5h 14m

$291

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Tue 4/28

2:19 pm-8:02 pm

1 stop4h 43m

Indianapolis

Sat 5/2

6:00 am-9:44 am

1 stop4h 44m

$301

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Thu 4/30

5:00 pm-11:55 pm

1 stop5h 55m

Indianapolis

Sun 5/3

7:20 am-11:55 am

1 stop5h 35m

$301
Quickest round-trip

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Sat 5/2

5:49 am-12:41 pm

1 stop5h 52m

Indianapolis

Thu 5/7

6:00 am-8:30 am

1 stop3h 30m

$301

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Wed 4/29

2:19 pm-8:07 pm

1 stop4h 48m

Indianapolis

Sat 5/2

12:47 pm-10:05 pm

2 stops10h 18m

$306

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Tue 6/16

5:25 pm-9:55 pm

1 stop3h 30m

Indianapolis

Fri 6/19

12:45 pm-9:40 pm

2 stops9h 55m

$341

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Tue 9/1

10:25 am-4:29 pm

1 stop5h 04m

Indianapolis

Wed 9/2

7:00 am-11:03 am

1 stop5h 03m

$371
Cheapest one-way

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Sat 6/13

4:00 pm-10:58 pm

1 stop5h 58m

$146

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Wed 10/7

4:10 pm-11:12 pm

1 stop6h 02m

$146

Panama CityIndianapolis

ECP - IND

ECPIND

Panama City NW Florida Beaches

Wed 7/15

7:46 am-3:19 pm

1 stop6h 33m

$146

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/10

Showing 1-10 of 18 resultsSorted by cheapest first
1
2

Compare providers for flights from Panama City to Indianapolis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Indianapolis in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City, Florida-Indianapolis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-Indianapolis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Indianapolis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City, Florida-Indianapolis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Indianapolis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Indianapolis

What is the cheapest month to book a flight from Panama City, Florida to Indianapolis?

Currently, October is the cheapest month in which you can book a flight from Panama City, Florida to Indianapolis (average of $79). Flying from Panama City, Florida to Indianapolis in December is currently the most expensive (average of $135). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ECP to IND?

Find hourly flight availability from Panama City to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 15, 2026.

When flying from Panama City, Florida to Indianapolis, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost to fly round-trip from Panama City, Florida to Indianapolis?

Reviews of airlines servicing Indianapolis

Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated April 15, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andAmerican Airlines from Panama City to Indianapolis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,331 reviews

Boarding

8.1

Crew

8.6

Comfort

8.0

Entertainment

7.5

Food

7.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Southwest
8.0
Very good
4,331 reviews
Southwest
8.0
Very good
4,331 reviews

Boarding

8.1

Crew

8.6

Comfort

8.0

Entertainment

7.5

Food

7.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Delta
7.9
Good
8,405 reviews
Southwest
8.0
Very good
4,331 reviews

Boarding

8.1

Crew

8.6

Comfort

8.0

Entertainment

7.5

Food

7.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
American Airlines
7.1
Good
11,580 reviews
Southwest
8.0
Very good
4,331 reviews

Boarding

8.1

Crew

8.6

Comfort

8.0

Entertainment

7.5

Food

7.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City, Florida to Indianapolis?

    A quick flight from Panama City, Florida to Indianapolis can take about 4h 57m. Delta provides one of the quickest options available for as low as $291. There are 647 mi between Panama City, Florida and Indianapolis.

  • What are the cheapest airlines flying from Panama City, Florida to Indianapolis round-trip?

    Cheapflights users have booked flights from Panama City, Florida to Indianapolis round-trip from $226. Other airlines that can offer you cheap pricing are American Airlines, from $276, and Southwest, from $303. Delta is currently priced 39% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Panama City, Florida to Indianapolis one-way?

    $127 is the cheapest one-way deal found within the past few days, from United Airlines. You may also be able to find cheap deals on American Airlines and Delta, with prices starting from $142 and $143, respectively.

  • Can I find deals for flights from Panama City to Indianapolis that include hotel bookings?

    Yes. In addition to deals on Panama City to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Indianapolis.

  • Can I find deals for business class flights from Panama City to Indianapolis?

    Yes. Cheapflights offers flight deals from Panama City to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Indianapolis?

    Currently, October is the cheapest month in which you can book a flight from Panama City, Florida to Indianapolis (average of $79). Flying from Panama City, Florida to Indianapolis in December is currently the most expensive (average of $135). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Terre Haute
Muncie
Greenwood
Fishers
Kokomo
Plainfield
Mooresville
Anderson
Franklin
Carmel
Noblesville
Bloomington
Crawfordsville

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama City to Indianapolis

See prices for flight routes from nearby airports that may be better suited for you.
Orlando to O'Hare Intl flights
Tampa to O'Hare Intl flights
Fort Lauderdale to O'Hare Intl flights
Miami to O'Hare Intl flights
Tampa to Midway flights
Jacksonville to O'Hare Intl flights
Orlando to Midway flights
Miami to Midway flights
Fort Lauderdale to Midway flights
Fort Myers to O'Hare Intl flights
West Palm Beach to O'Hare Intl flights
Jacksonville to Midway flights
Sarasota to O'Hare Intl flights
Orlando to Cincinnati flights
Fort Lauderdale to Indianapolis flights
Miami to Indianapolis flights
Tampa to Cincinnati flights
Orlando to Indianapolis flights
Miami to Cincinnati flights
Tampa to Indianapolis flights
Pensacola to O'Hare Intl flights
Orlando to Louisville flights
Fort Lauderdale to Cincinnati flights
West Palm Beach to Midway flights
Tampa to Louisville flights
Fort Myers to Midway flights
Fort Myers to Indianapolis flights
Fort Myers to Cincinnati flights
Jacksonville to Cincinnati flights
Sarasota to Midway flights
West Palm Beach to Indianapolis flights
Orlando Sanford Intl to Cincinnati flights
Panama City to O'Hare Intl flights
Miami to Louisville flights
West Palm Beach to Cincinnati flights
Orlando to Dayton flights
Valparaiso to O'Hare Intl flights
Orlando Sanford Intl to Indianapolis flights
Fort Lauderdale to Louisville flights
Tampa to Dayton flights
St Petersburg to Cincinnati flights
Pensacola to Indianapolis flights
Jacksonville to Dayton flights
Jacksonville to Louisville flights
St Petersburg to Indianapolis flights
Panama City to Midway flights
Pensacola to Cincinnati flights
Jacksonville to Indianapolis flights
Pensacola to Midway flights

Top 3 airlines flying from Panama City to Indianapolis

Discover the top 3 airlines that operate flights from Panama City to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 15, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$226Average$318FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$276Average$406FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$303Average$407FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.
Site
©2026 Cheapflights