$162+ Cheap flights from Panama City, FL to Indianapolis (ECP - IND)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/28. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — IND
Nov 3 — Nov 101
Round-trip
1 adult, Economy
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Find cheap flights from Panama City to Indianapolis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama City to Indianapolis
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Best
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Cheapest flights from Panama City to IndianapolisExplore the most affordable flight options available from Panama City to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 4, 2026.
Explore the most affordable flight options available from Panama City to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 4, 2026.
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/314:55 pm -
1 stop5h 24m
Sat 11/79:00 am -
1 stop6h 28m
Deal found 9/29![United Airlines logo]()
$323
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/115:41 pm -
1 stop5h 12m
Sun 11/158:06 pm -
1 stop4h 42m
Deal found 9/30![American Airlines logo]()
$337
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/141:35 pm -
2 stops8h 55m
Sat 11/286:20 am -
1 stop3h 35m
Deal found 9/29![Southwest logo]()
$342
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:42 pm -
1 stop4h 55m
Fri 11/68:06 pm -
1 stop4h 42m
Deal found 9/29![American Airlines logo]()
$351
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/104:10 pm -
1 stop3h 40m
Thu 11/1212:35 pm -
2 stops9h 00m
Deal found 9/29![Southwest logo]()
$366
This Delta deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/251:34 pm -
1 stop4h 20m
Sun 11/298:08 pm -
1 stop4h 16m
Deal found 10/1![Delta logo]()
$371
Best flights from Panama City to IndianapolisDiscover carefully curated flight deals from Panama City to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 4, 2026.
Discover carefully curated flight deals from Panama City to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 4, 2026.
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/119:06 am -
2 stops8h 40m
Wed 11/181:40 pm -
2 stops8h 56m
Deal found 9/29![United Airlines logo]()
$333
This Southwest deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:55 pm -
1 stop3h 45m
Mon 11/237:00 am -
1 stop3h 35m
Deal found 10/1![Southwest logo]()
$337
This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/156:55 pm -
1 stop4h 45m
Thu 11/197:05 am -
1 stop4h 25m
Deal found 9/29![Delta logo]()
$351
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/141:35 pm -
2 stops8h 55m
Sat 11/286:20 am -
1 stop3h 35m
Deal found 9/29![Southwest logo]()
$342
This United Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/314:55 pm -
1 stop5h 24m
Sat 11/79:00 am -
1 stop6h 28m
Deal found 10/3![United Airlines logo]()
$351
This Delta deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/251:34 pm -
1 stop4h 20m
Sun 11/298:08 pm -
1 stop4h 16m
Deal found 10/1![Delta logo]()
$371
This Southwest deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/87:30 am -
1 stop5h 00m
Thu 12/104:20 pm -
1 stop5h 10m
Deal found 10/2![Southwest logo]()
$351
This Southwest deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:25 pm -
1 stop4h 25m
Sun 11/295:10 am -
1 stop7h 10m
Deal found 10/2![Southwest logo]()
$385
Last-minute flights from Panama City to IndianapolisDiscover last-minute flight deals from Panama City to Indianapolis. Data last updated October 4, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Indianapolis. Data last updated October 4, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:42 pm -
1 stop4h 55m
Fri 11/68:06 pm -
1 stop4h 42m
Deal found 9/29![American Airlines logo]()
$351
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates ” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/314:55 pm -
1 stop5h 24m
Sat 11/79:00 am -
1 stop6h 28m
Deal found 9/29![United Airlines logo]()
$323
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/104:10 pm -
1 stop3h 40m
Thu 11/1212:35 pm -
2 stops9h 00m
Deal found 9/29![Southwest logo]()
$366
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/115:41 pm -
1 stop5h 12m
Sun 11/158:06 pm -
1 stop4h 42m
Deal found 9/30![American Airlines logo]()
$337
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/141:35 pm -
2 stops8h 55m
Sat 11/286:20 am -
1 stop3h 35m
Deal found 9/29![Southwest logo]()
$342
This Delta deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/251:34 pm -
1 stop4h 20m
Sun 11/298:08 pm -
1 stop4h 16m
Deal found 10/1![Delta logo]()
$371
One-way flights from Panama City to IndianapolisSearch for one-way flight options from Panama City to Indianapolis. Find affordable one-way fares based on user searches. Data last updated October 4, 2026.
Search for one-way flight options from Panama City to Indianapolis. Find affordable one-way fares based on user searches. Data last updated October 4, 2026.
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/283:05 pm -
1 stop7h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![United Airlines logo]()
$162
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2111:30 am -
2 stops9h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Southwest logo]()
$172
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:40 am -
2 stops9h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Southwest logo]()
$173
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/304:55 pm -
1 stop5h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![United Airlines logo]()
$176
This Delta deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:59 pm -
1 stop4h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/1![Delta logo]()
$180
This Delta deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:00 am -
1 stop6h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/1![Delta logo]()
$183
This Delta deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:55 pm -
1 stop4h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![Delta logo]()
$196
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:41 pm -
1 stop5h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/1![American Airlines logo]()
$200
Find flight deals from Panama City to Indianapolis
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $323 (American Airlines) |
One-way from | $162 (United Airlines) |
Popular in | December |
Cheapest in | October |
Average price | $290 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 4, 2026.
Use the filters below to find and compare flights from Panama City to Indianapolis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CityIndianapolis
ECP Panama City NW Florida Beaches - IND Indianapolis
ECPIND
Panama City NW Florida Beaches
Tue 12/29
6:55 pm-12:42 am
1 stop4h 47m
Indianapolis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$162
Panama CityIndianapolis
ECP Panama City NW Florida Beaches - IND Indianapolis
ECPIND
Panama City NW Florida Beaches
Thu 12/3
6:59 pm-12:52 am
1 stop4h 53m
Indianapolis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$162
Panama CityIndianapolis
ECP Panama City NW Florida Beaches - IND Indianapolis
ECPIND
Panama City NW Florida Beaches
Wed 12/2
6:00 am-12:59 pm
1 stop5h 59m
Indianapolis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$162
Panama CityIndianapolis
ECP Panama City NW Florida Beaches - IND Indianapolis
ECPIND
Panama City NW Florida Beaches
Thu 10/22
6:20 pm-12:25 am
1 stop5h 05m
Indianapolis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$162
Panama CityIndianapolis
ECP Panama City NW Florida Beaches - IND Indianapolis
ECPIND
Panama City NW Florida Beaches
Wed 11/4
11:30 am-11:47 pm
2 stops11h 17m
Indianapolis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$167
Panama CityIndianapolis
ECP Panama City NW Florida Beaches - IND Indianapolis
ECPIND
Panama City NW Florida Beaches
Wed 10/21
11:30 am-9:45 pm
2 stops9h 15m
Indianapolis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$172
Panama CityIndianapolis
ECP Panama City NW Florida Beaches - IND Indianapolis
ECPIND
Panama City NW Florida Beaches
Mon 10/26
1:55 pm-12:25 am
1 stop9h 30m
Indianapolis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$172
Panama CityIndianapolis
ECP Panama City NW Florida Beaches - IND Indianapolis
ECPIND
Panama City NW Florida Beaches
Tue 10/27
7:40 am-6:05 pm
2 stops9h 25m
Indianapolis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$173
Panama CityIndianapolis
ECP Panama City NW Florida Beaches - IND Indianapolis
ECPIND
Panama City NW Florida Beaches
Tue 10/20
2:50 pm-11:30 pm
1 stop7h 40m
Indianapolis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$176
Panama CityIndianapolis
ECP Panama City NW Florida Beaches - IND Indianapolis
ECPIND
Panama City NW Florida Beaches
Wed 12/2
3:50 pm-9:50 pm
1 stop5h 00m
Indianapolis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$176
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from Panama City to Indianapolis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Indianapolis in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Panama City, Florida-Indianapolis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-Indianapolis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Indianapolis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Panama City, Florida-Indianapolis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Indianapolis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Panama City to Indianapolis
Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Panama City with our price prediction graph.
ECP-IND
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Indianapolis
Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated October 4, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andAmerican Airlines from Panama City to Indianapolis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Food
7.0
Entertainment
7.5
Crew
8.6
Boarding
8.1
Overall
7.9
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Comfort
8.0
Food
7.0
Entertainment
7.5
Crew
8.6
Boarding
8.1
Overall
7.9
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Comfort
8.0
Food
7.0
Entertainment
7.5
Crew
8.6
Boarding
8.1
Overall
7.9
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Comfort
8.0
Food
7.0
Entertainment
7.5
Crew
8.6
Boarding
8.1
Overall
7.9
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Related info for your journey
Find useful and relevant information for your journey from Panama City to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Indianapolis?
Book flights to Indianapolis if you plan to visit one of these locationsTerre Haute
Greenwood
Plainfield
Fishers
Muncie
Kokomo
Westfield
Franklin
Mooresville
Crawfordsville
Anderson
Noblesville
Bloomington
Speedway
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Other flights to Indianapolis
Explore flights to Indianapolis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 4, 2026.
Panama City and Indianapolis flights
Browse other Panama City and Indianapolis flight options. Last updated on October 4, 2026.
Other flights from Panama City
Browse through other flights departing from Panama City. Flights are based on user searches made on Cheapflights and were last updated on October 4, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Panama City to Indianapolis
Discover the top 3 airlines that operate flights from Panama City to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$186 | Average$398 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$246 | Average$319 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$290 | Average$378 | FlexibilityNo cancel fee | On-time63% |