$162+ Cheap flights from Panama City, FL to Indianapolis (ECP - IND)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/3. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — IND
Oct 2 — Oct 91
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Panama City to Indianapolis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama City to Indianapolis
Cheapest
Best
Last-minute
One-way
Cheapest flights from Panama City to IndianapolisExplore the most affordable flight options available from Panama City to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 2, 2026.
Explore the most affordable flight options available from Panama City to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 2, 2026.
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/234:20 pm -
1 stop3h 45m
Sat 9/267:55 am -
Nonstop2h 00m
Deal found 9/1![Southwest logo]()
$322
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:20 pm -
1 stop5h 05m
Mon 10/126:25 pm -
1 stop5h 53m
Deal found 9/1![Delta logo]()
$323
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/94:30 pm -
1 stop5h 54m
Sat 10/175:14 pm -
1 stop3h 49m
Deal found 9/1![Delta logo]()
$327
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/610:10 am -
1 stop7h 30m
Mon 11/95:50 am -
2 stops9h 35m
Deal found 9/1![Southwest logo]()
$332
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/301:32 pm -
1 stop6h 32m
Wed 10/77:58 pm -
1 stop4h 55m
Deal found 9/1![American Airlines logo]()
$334
This Southwest deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/154:20 pm -
1 stop3h 45m
Sat 9/1911:35 am -
2 stops7h 40m
Deal found 8/31![Southwest logo]()
$336
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:30 am -
2 stops9h 03m
Tue 9/156:00 am -
2 stops8h 52m
Deal found 8/28![United Airlines logo]()
$341
This Southwest deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:30 am -
2 stops7h 15m
Mon 11/237:00 am -
1 stop3h 35m
Deal found 8/28![Southwest logo]()
$346
This Delta deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:00 am -
1 stop6h 02m
Wed 10/710:21 am -
1 stop4h 34m
Deal found 8/31![Delta logo]()
$357
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/307:45 am -
1 stop3h 40m
Wed 10/76:50 am -
2 stops8h 50m
Deal found 9/1![Southwest logo]()
$358
Best flights from Panama City to IndianapolisDiscover carefully curated flight deals from Panama City to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 2, 2026.
Discover carefully curated flight deals from Panama City to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 2, 2026.
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:20 pm -
1 stop5h 05m
Mon 10/126:25 pm -
1 stop5h 53m
Deal found 9/1![Delta logo]()
$323
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/610:10 am -
1 stop7h 30m
Mon 11/912:35 pm -
1 stop5h 45m
Deal found 9/1![Southwest logo]()
$327
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/94:30 pm -
1 stop5h 54m
Sat 10/175:14 pm -
1 stop3h 49m
Deal found 9/1![Delta logo]()
$327
This Southwest deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/154:20 pm -
1 stop3h 45m
Sat 9/197:10 am -
1 stop8h 45m
Deal found 8/31![Southwest logo]()
$336
This Delta deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:20 pm -
1 stop5h 12m
Sun 9/277:05 am -
1 stop6h 34m
Deal found 8/28![Delta logo]()
$331
This Southwest deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:30 am -
2 stops7h 15m
Mon 11/237:00 am -
1 stop3h 35m
Deal found 8/28![Southwest logo]()
$346
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/307:45 am -
1 stop3h 40m
Wed 10/76:50 am -
2 stops8h 50m
Deal found 9/1![Southwest logo]()
$358
This Southwest deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/181:30 pm -
2 stops8h 35m
Mon 9/216:00 am -
1 stop7h 50m
Deal found 8/30![Southwest logo]()
$380
This Southwest deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/131:55 pm -
1 stop8h 25m
Tue 9/1511:00 am -
2 stops8h 15m
Deal found 8/28![Southwest logo]()
$380
Last-minute flights from Panama City to IndianapolisDiscover last-minute flight deals from Panama City to Indianapolis. Data last updated September 2, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Indianapolis. Data last updated September 2, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:30 am -
2 stops9h 03m
Tue 9/156:00 am -
2 stops8h 52m
Deal found 8/28![United Airlines logo]()
$341
This Southwest deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/154:20 pm -
1 stop3h 45m
Sat 9/1911:35 am -
2 stops7h 40m
Deal found 8/31![Southwest logo]()
$336
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/234:20 pm -
1 stop3h 45m
Sat 9/267:55 am -
Nonstop2h 00m
Deal found 9/1![Southwest logo]()
$322
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/301:32 pm -
1 stop6h 32m
Wed 10/77:58 pm -
1 stop4h 55m
Deal found 9/1![American Airlines logo]()
$334
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/307:45 am -
1 stop3h 40m
Wed 10/76:50 am -
2 stops8h 50m
Deal found 9/1![Southwest logo]()
$358
This Delta deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:00 am -
1 stop6h 02m
Wed 10/710:21 am -
1 stop4h 34m
Deal found 8/31![Delta logo]()
$357
This Southwest deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/37:40 am -
1 stop4h 55m
Wed 10/76:50 am -
2 stops8h 50m
Deal found 8/31![Southwest logo]()
$362
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:20 pm -
1 stop5h 05m
Mon 10/126:25 pm -
1 stop5h 53m
Deal found 9/1![Delta logo]()
$323
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/94:30 pm -
1 stop5h 54m
Sat 10/175:14 pm -
1 stop3h 49m
Deal found 9/1![Delta logo]()
$327
One-way flights from Panama City to IndianapolisSearch for one-way flight options from Panama City to Indianapolis. Find affordable one-way fares based on user searches. Data last updated September 2, 2026.
Search for one-way flight options from Panama City to Indianapolis. Find affordable one-way fares based on user searches. Data last updated September 2, 2026.
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/284:35 pm -
1 stop5h 47m
Deal found 9/2![Delta logo]()
$162
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:34 pm -
1 stop5h 51m
Deal found 9/2![Delta logo]()
$166
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/281:30 pm -
2 stops8h 30m
Deal found 9/2![Southwest logo]()
$167
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:40 am -
2 stops9h 25m
Deal found 9/1![Southwest logo]()
$177
This Southwest deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2011:30 am -
2 stops9h 30m
Deal found 8/28![Southwest logo]()
$181
This Delta deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:20 pm -
1 stop5h 05m
Deal found 8/28![Delta logo]()
$192
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:55 am -
2 stops10h 15m
Deal found 9/2![Southwest logo]()
$197
This Delta deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/276:19 pm -
1 stop5h 13m
Deal found 8/28![Delta logo]()
$205
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/299:06 am -
2 stops10h 40m
Deal found 9/2![United Airlines logo]()
$207
Find flight deals from Panama City to Indianapolis
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 2, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $322 (Southwest) |
One-way from | $162 (Delta) |
Popular in | December |
Cheapest in | November |
Average price | $375 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 2, 2026.
Use the filters below to find and compare flights from Panama City to Indianapolis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CityIndianapolis
ECP Panama City NW Florida Beaches - IND Indianapolis
ECPIND
Panama City NW Florida Beaches
Thu 10/8
6:20 pm-12:25 am
1 stop5h 05m
Indianapolis
Mon 10/12
6:25 pm-11:18 pm
1 stop5h 53m
$323
Panama CityIndianapolis
ECP Panama City NW Florida Beaches - IND Indianapolis
ECPIND
Panama City NW Florida Beaches
Fri 11/6
10:10 am-6:40 pm
1 stop7h 30m
Indianapolis
Mon 11/9
12:35 pm-5:20 pm
1 stop5h 45m
$327
Quickest round-trip
Panama CityIndianapolis
ECP Panama City NW Florida Beaches - IND Indianapolis
ECPIND
Panama City NW Florida Beaches
Fri 10/9
4:30 pm-11:24 pm
1 stop5h 54m
Indianapolis
Sat 10/17
5:14 pm-8:03 pm
1 stop3h 49m
$327
Panama CityIndianapolis
ECP Panama City NW Florida Beaches - IND Indianapolis
ECPIND
Panama City NW Florida Beaches
Thu 9/24
6:20 pm-12:32 am
1 stop5h 12m
Indianapolis
Sun 9/27
7:05 am-12:39 pm
1 stop6h 34m
$331
Panama CityIndianapolis
ECP Panama City NW Florida Beaches - IND Indianapolis
ECPIND
Panama City NW Florida Beaches
Tue 9/15
4:20 pm-9:05 pm
1 stop3h 45m
Indianapolis
Sat 9/19
7:10 am-2:55 pm
1 stop8h 45m
$336
Panama CityIndianapolis
ECP Panama City NW Florida Beaches - IND Indianapolis
ECPIND
Panama City NW Florida Beaches
Thu 11/19
7:30 am-3:45 pm
2 stops7h 15m
Indianapolis
Mon 11/23
7:00 am-9:35 am
1 stop3h 35m
$346
Panama CityIndianapolis
ECP Panama City NW Florida Beaches - IND Indianapolis
ECPIND
Panama City NW Florida Beaches
Wed 9/30
7:45 am-12:25 pm
1 stop3h 40m
Indianapolis
Wed 10/7
6:50 am-2:40 pm
2 stops8h 50m
$358
Panama CityIndianapolis
ECP Panama City NW Florida Beaches - IND Indianapolis
ECPIND
Panama City NW Florida Beaches
Fri 9/18
1:30 pm-11:05 pm
2 stops8h 35m
Indianapolis
Mon 9/21
6:00 am-12:50 pm
1 stop7h 50m
$380
Panama CityIndianapolis
ECP Panama City NW Florida Beaches - IND Indianapolis
ECPIND
Panama City NW Florida Beaches
Sun 9/13
1:55 pm-11:20 pm
1 stop8h 25m
Indianapolis
Tue 9/15
11:00 am-6:15 pm
2 stops8h 15m
$380
Cheapest one-way
Panama CityIndianapolis
ECP Panama City NW Florida Beaches - IND Indianapolis
ECPIND
Panama City NW Florida Beaches
Tue 11/3
12:30 pm-6:00 pm
1 stop4h 30m
$162
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Panama City to Indianapolis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Indianapolis in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Panama City, Florida-Indianapolis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-Indianapolis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Indianapolis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Panama City, Florida-Indianapolis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Indianapolis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Panama City to Indianapolis
Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Panama City with our price prediction graph.
ECP-IND
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to Indianapolis
What is the cheapest time of day to fly from ECP to IND?
Find hourly flight availability from Panama City to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 2, 2026.
When flying from Panama City, Florida to Indianapolis, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
How much does it cost to fly round-trip from Panama City, Florida to Indianapolis?
Airfare is typical for this route at the moment.
Panama City, Florida to Indianapolis flights typically cost between $282 and $485 in September.The cheapest round-trip price found within the last 5 days was $322 on Southwest (Sep 23-Sep 26).
Reviews of airlines servicing Indianapolis
Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated September 2, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andAmerican Airlines from Panama City to Indianapolis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Comfort
8.0
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Entertainment
7.5
Comfort
8.0
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Entertainment
7.5
Comfort
8.0
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Entertainment
7.5
Comfort
8.0
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Related info for your journey
Find useful and relevant information for your journey from Panama City to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Indianapolis?
Book flights to Indianapolis if you plan to visit one of these locationsTerre Haute
Greenwood
Plainfield
Fishers
Muncie
Kokomo
Westfield
Franklin
Mooresville
Anderson
Crawfordsville
Carmel
Noblesville
Bloomington
Speedway
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Indianapolis flight routes
Other flight options
Other flights from Panama City
Popular flights
Alternative routes for Panama City to Indianapolis
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Indianapolis by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Panama City to Indianapolis by cabin class
Find flights from Panama City to Indianapolis, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Indianapolis
Explore flights to Indianapolis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 2, 2026.
Panama City and Indianapolis flights
Browse other Panama City and Indianapolis flight options. Last updated on September 2, 2026.
Other flights from Panama City
Browse through other flights departing from Panama City. Flights are based on user searches made on Cheapflights and were last updated on September 2, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Panama City to Indianapolis
Discover the top 3 airlines that operate flights from Panama City to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 2, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$186 | Average$404 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$246 | Average$330 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$290 | Average$378 | FlexibilityNo cancel fee | On-time63% |