$98+ Cheap flights from Mesa, AZ to Indianapolis (IND)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/24. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — IND
Sep 18 — Sep 251
Round-trip
1 adult, Economy
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Find cheap flights from Mesa to Indianapolis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Mesa to Indianapolis are usually found in September or November, booked 87 days in advance, depart on a Thursday or Saturday and return on a Thursday
Cheap flight deals from Mesa to Indianapolis
Cheapest
Best
Last-minute
One-way
Cheapest flights from Mesa to IndianapolisExplore the most affordable flight options available from Mesa to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 19, 2026.
Explore the most affordable flight options available from Mesa to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 19, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/37:55 pm -
1 stop16h 02m
Sat 11/72:52 pm -
1 stop11h 55m
Deal found 8/17![Frontier logo]()
$193
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:15 am -
1 stop5h 58m
Mon 10/263:58 pm -
1 stop22h 39m
Deal found 8/15![Frontier logo]()
$196
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:55 pm -
1 stop16h 02m
Tue 11/172:52 pm -
1 stop26h 43m
Deal found 8/18![Frontier logo]()
$198
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1210:06 am -
1 stop7h 34m
Tue 11/172:52 pm -
1 stop26h 43m
Deal found 8/18![Frontier logo]()
$199
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:55 pm -
1 stop16h 02m
Tue 11/172:52 pm -
1 stop26h 43m
Deal found 8/18![Frontier logo]()
$201
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/109:15 am -
1 stop7h 46m
Mon 9/144:12 pm -
1 stop10h 31m
Deal found 8/18![Frontier logo]()
$202
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:15 am -
1 stop5h 58m
Tue 10/204:08 pm -
1 stop6h 38m
Deal found 8/15![Frontier logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/37:55 pm -
1 stop16h 02m
Fri 11/62:52 pm -
1 stop26h 43m
Deal found 8/16![Frontier logo]()
$207
Best flights from Mesa to IndianapolisDiscover carefully curated flight deals from Mesa to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 19, 2026.
Discover carefully curated flight deals from Mesa to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 19, 2026.
This Southwest deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:55 pm -
Nonstop3h 25m
Mon 9/147:10 pm -
Nonstop3h 45m
Deal found 8/15![Southwest logo]()
$397
This Alaska Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:02 am -
1 stop9h 00m
Wed 10/287:02 am -
1 stop11h 08m
Deal found 8/18![Alaska Airlines logo]()
$417
This Southwest deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/73:30 pm -
Nonstop3h 15m
Tue 11/103:45 pm -
Nonstop3h 50m
Deal found 8/18![Southwest logo]()
$397
This Southwest deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:00 am -
1 stop6h 10m
Tue 10/136:00 am -
Nonstop3h 50m
Deal found 8/16![Southwest logo]()
$407
This Southwest deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:45 pm -
Nonstop3h 20m
Sat 10/246:35 am -
1 stop6h 10m
Deal found 8/15![Southwest logo]()
$407
This Southwest deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:45 am -
Nonstop3h 20m
Sun 10/49:10 pm -
Nonstop3h 50m
Deal found 8/18![Southwest logo]()
$414
This Southwest deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/11:40 pm -
2 stops6h 25m
Mon 10/57:25 pm -
2 stops7h 00m
Deal found 8/14![Southwest logo]()
$427
This Southwest deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/31:35 pm -
2 stops7h 10m
Sat 11/710:40 am -
2 stops8h 15m
Deal found 8/17![Southwest logo]()
$427
This Southwest deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/52:05 pm -
2 stops8h 10m
Sun 11/86:30 am -
2 stops7h 20m
Deal found 8/17![Southwest logo]()
$444
This Southwest deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:55 pm -
Nonstop3h 25m
Sun 9/277:35 pm -
Nonstop3h 45m
Deal found 8/15![Southwest logo]()
$455
This Southwest deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:35 pm -
Nonstop3h 20m
Sun 10/187:30 pm -
1 stop6h 40m
Deal found 8/14![Southwest logo]()
$465
This Southwest deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/19:35 am -
Nonstop3h 25m
Wed 9/307:20 am -
Nonstop3h 45m
Deal found 8/17![Southwest logo]()
$489
Last-minute flights from Mesa to IndianapolisDiscover last-minute flight deals from Mesa to Indianapolis. Data last updated August 19, 2026 and is based on user searches.
Discover last-minute flight deals from Mesa to Indianapolis. Data last updated August 19, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/98:39 pm -
1 stop13h 33m
Mon 9/147:48 pm -
2 stops29h 02m
Deal found 8/17![Multiple Airlines logo]()
$214
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/109:15 am -
1 stop7h 46m
Mon 9/144:12 pm -
1 stop10h 31m
Deal found 8/18![Frontier logo]()
$202
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/177:22 am -
2 stops28h 55m
Mon 9/214:12 pm -
1 stop10h 31m
Deal found 8/19![Frontier logo]()
$227
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/248:56 pm -
1 stop15h 21m
Sat 10/34:12 pm -
1 stop6h 39m
Deal found 8/15![Frontier logo]()
$231
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/298:56 pm -
1 stop15h 21m
Sat 10/34:12 pm -
1 stop6h 39m
Deal found 8/15![Frontier logo]()
$220
One-way flights from Mesa to IndianapolisSearch for one-way flight options from Mesa to Indianapolis. Find affordable one-way fares based on user searches. Data last updated August 19, 2026.
Search for one-way flight options from Mesa to Indianapolis. Find affordable one-way fares based on user searches. Data last updated August 19, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:15 am -
1 stop5h 58m
Deal found 8/17![Frontier logo]()
$98
This Kiwi.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/153:21 pm -
1 stop20h 56m
Deal found 8/14![Frontier logo]()
$101
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/109:15 am -
1 stop7h 46m
Deal found 8/18![Frontier logo]()
$102
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/171:42 pm -
1 stop22h 15m
Deal found 8/17![Frontier logo]()
$103
This Kiwi.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/127:22 pm -
2 stops44h 42m
Deal found 8/14![Frontier logo]()
$106
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:55 pm -
1 stop16h 02m
Deal found 8/18![Frontier logo]()
$108
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/148:56 pm -
1 stop15h 21m
Deal found 8/17![Frontier logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/98:39 pm -
1 stop13h 33m
Deal found 8/16![Multiple Airlines logo]()
$112
Find flight deals from Mesa to Indianapolis
Keep the following information in mind while searching for Mesa to Indianapolis flight deals. Data was last updated August 19, 2026.
Round-trip from | $193 (Kiwi.com) |
|---|---|
One-way from | $98 (Kiwi.com) |
Popular in | April |
Cheapest in | September |
Average price | $472 |
Cheapflights Fare Finder
Customize your flight search to find flights from Mesa to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 19, 2026.
Use the filters below to find and compare flights from Mesa to Indianapolis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PhoenixIndianapolis
PHX Phoenix Sky Harbor Intl - IND Indianapolis
PHXIND
Phoenix Sky Harbor Intl
Thu 9/10
6:55 pm-1:20 am
Nonstop3h 25m
Indianapolis
Mon 9/14
7:10 pm-7:55 pm
Nonstop3h 45m
$397
Quickest round-trip
PhoenixIndianapolis
PHX Phoenix Sky Harbor Intl - IND Indianapolis
PHXIND
Phoenix Sky Harbor Intl
Sat 11/7
3:30 pm-8:45 pm
Nonstop3h 15m
Indianapolis
Tue 11/10
3:45 pm-5:35 pm
Nonstop3h 50m
$397
PhoenixIndianapolis
PHX Phoenix Sky Harbor Intl - IND Indianapolis
PHXIND
Phoenix Sky Harbor Intl
Thu 10/8
5:00 am-2:10 pm
1 stop6h 10m
Indianapolis
Tue 10/13
6:00 am-6:50 am
Nonstop3h 50m
$407
PhoenixIndianapolis
PHX Phoenix Sky Harbor Intl - IND Indianapolis
PHXIND
Phoenix Sky Harbor Intl
Thu 10/22
6:45 pm-1:05 am
Nonstop3h 20m
Indianapolis
Sat 10/24
6:35 am-9:45 am
1 stop6h 10m
$407
PhoenixIndianapolis
PHX Phoenix Sky Harbor Intl - IND Indianapolis
PHXIND
Phoenix Sky Harbor Intl
Thu 10/1
7:45 am-2:05 pm
Nonstop3h 20m
Indianapolis
Sun 10/4
9:10 pm-10:00 pm
Nonstop3h 50m
$414
PhoenixIndianapolis
PHX Phoenix Sky Harbor Intl - IND Indianapolis
PHXIND
Phoenix Sky Harbor Intl
Tue 10/27
6:02 am-6:02 pm
1 stop9h 00m
Indianapolis
Wed 10/28
7:02 am-3:10 pm
1 stop11h 08m
$417
PhoenixIndianapolis
PHX Phoenix Sky Harbor Intl - IND Indianapolis
PHXIND
Phoenix Sky Harbor Intl
Thu 10/1
1:40 pm-11:05 pm
2 stops6h 25m
Indianapolis
Mon 10/5
7:25 pm-11:25 pm
2 stops7h 00m
$427
PhoenixIndianapolis
PHX Phoenix Sky Harbor Intl - IND Indianapolis
PHXIND
Phoenix Sky Harbor Intl
Tue 11/3
1:35 pm-10:45 pm
2 stops7h 10m
Indianapolis
Sat 11/7
10:40 am-4:55 pm
2 stops8h 15m
$427
PhoenixIndianapolis
PHX Phoenix Sky Harbor Intl - IND Indianapolis
PHXIND
Phoenix Sky Harbor Intl
Thu 11/5
2:05 pm-12:15 am
2 stops8h 10m
Indianapolis
Sun 11/8
6:30 am-11:50 am
2 stops7h 20m
$444
PhoenixIndianapolis
PHX Phoenix Sky Harbor Intl - IND Indianapolis
PHXIND
Phoenix Sky Harbor Intl
Thu 9/24
6:55 pm-1:20 am
Nonstop3h 25m
Indianapolis
Sun 9/27
7:35 pm-8:20 pm
Nonstop3h 45m
$455
Showing 1-10 of 21 resultsSorted by cheapest first
Best time to book a flight from Mesa to Indianapolis
Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Mesa with our price prediction graph.
PHX-IND
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Mesa to Indianapolis
MS9-IND
PHX-IND
What is the cheapest time of day to fly from MS9 to IND?
Find hourly flight availability from Mesa to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 19, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mesa to Indianapolis as you normally would.
Weekly flight availability from Mesa to Indianapolis
Explore weekly flight availability from Mesa to Indianapolis. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated August 19, 2026.
The most flights from MS9 to IND are scheduled on a Monday (3 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (1 on average).
How much does it cost to fly round-trip from Mesa to Indianapolis?
Airfare is below average for this route at the moment.
Mesa to Indianapolis flights typically cost between $384 and $570 in November.The cheapest round-trip price found within the last 5 days was $193 on Frontier (Nov 3-Nov 7).
What is the cheapest day to fly from Mesa to Indianapolis?
Use this chart to determine the cheapest time to fly round-trip from Mesa to Indianapolis. Price data was last updated on August 15, 2026.
Travelers seeking maximum savings on their Mesa to Indianapolis flight should consider departing on Sunday at noon when fares are most often at their lowest. Saturday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Indianapolis
Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated August 19, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Mesa to Indianapolis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Boarding
8.1
Food
7.0
Crew
8.6
Overall
8.0
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Entertainment
7.5
Boarding
8.1
Food
7.0
Crew
8.6
Overall
8.0
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Entertainment
7.5
Boarding
8.1
Food
7.0
Crew
8.6
Overall
8.0
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Entertainment
7.5
Boarding
8.1
Food
7.0
Crew
8.6
Overall
8.0
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Entertainment
7.5
Boarding
8.1
Food
7.0
Crew
8.6
Overall
8.0
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Entertainment
7.5
Boarding
8.1
Food
7.0
Crew
8.6
Overall
8.0
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Mesa to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Indianapolis?
Book flights to Indianapolis if you plan to visit one of these locationsTerre Haute
Greenwood
Plainfield
Fishers
Muncie
Kokomo
Westfield
Franklin
Mooresville
Anderson
Crawfordsville
Carmel
Noblesville
Bloomington
Speedway
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Other flights to Indianapolis
Explore flights to Indianapolis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 19, 2026.
Mesa and Indianapolis flights
Browse other Mesa and Indianapolis flight options. Last updated on August 19, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Mesa to Indianapolis flights
Consider these flights traveling from Mesa to Indianapolis.
Top 5 airlines flying from Mesa to Indianapolis
Discover the top 5 airlines that operate flights from Mesa to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 19, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$142 | Average$542 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$165 | Average$263 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$236 | Average$336 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$355 | Average$502 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$357 | Average$500 | FlexibilityNo cancel fee | On-time71% |