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$126+ Cheap flights from Roanoke (ROA) to Indiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/6. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — IND
Apr 10 — Apr 171
Fri 4/10
Fri 4/17
1 adult, Economy
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Cheap flight deals from Roanoke to Indiana

Cheapest flights from Roanoke to Indiana
Explore the most affordable flight options available from Roanoke to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 11, 2026.

This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:45 am
ROA
-
ORD
Nonstop2h 09m
United Airlines
Mon 4/66:50 am
ORD
-
ROA
Nonstop1h 54m
United Airlines
Deal found 3/6$229
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/27:50 am
ROA
-
ORD
Nonstop2h 18m
American Airlines
Sun 4/59:07 pm
ORD
-
ROA
Nonstop1h 52m
American Airlines
Deal found 3/8$230
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/97:59 pm
ROA
-
ORD
1 stop4h 44m
United Airlines
Mon 4/139:35 pm
ORD
-
ROA
Nonstop2h 02m
United Airlines
Deal found 3/6$239
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/87:28 am
ROA
-
ORD
Nonstop2h 30m
American Airlines
Sun 5/109:15 pm
ORD
-
ROA
Nonstop1h 59m
American Airlines
Deal found 3/6$249
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1511:09 am
ROA
-
ORD
1 stop6h 12m
American Airlines
Sun 4/199:11 pm
ORD
-
ROA
Nonstop1h 59m
American Airlines
Deal found 3/9$250
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/47:50 pm
ROA
-
CVG
1 stop4h 05m
Delta
Mon 8/105:50 pm
CVG
-
ROA
1 stop6h 00m
Delta
Deal found 3/6$259
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/247:59 pm
ROA
-
ORD
1 stop4h 44m
United Airlines
Mon 4/2710:30 am
ORD
-
ROA
Nonstop1h 59m
United Airlines
Deal found 3/9$259
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/3010:30 am
ROA
-
ORD
1 stop5h 10m
United Airlines
Sat 6/69:15 pm
ORD
-
ROA
Nonstop2h 09m
United Airlines
Deal found 3/6$260
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/316:15 am
ROA
-
ORD
1 stop6h 38m
United Airlines
Sat 8/19:15 pm
ORD
-
ROA
Nonstop2h 09m
United Airlines
Deal found 3/6$261
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/186:40 am
ROA
-
ORD
Nonstop2h 13m
United Airlines
Mon 6/226:45 am
ORD
-
ROA
Nonstop2h 01m
United Airlines
Deal found 3/9$262
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/257:50 pm
ROA
-
CVG
1 stop4h 03m
United Airlines
Mon 3/306:00 am
CVG
-
ROA
1 stop3h 49m
United Airlines
Deal found 3/8$264
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/202:09 pm
ROA
-
ORD
Nonstop2h 04m
United Airlines
Mon 5/256:45 am
ORD
-
ROA
Nonstop2h 01m
United Airlines
Deal found 3/7$268

Find flight deals from Roanoke to Indiana

Keep the following information in mind while searching for Roanoke to Indiana flight deals. Data was last updated March 11, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$229
(United Airlines)

One-way from

$126
(American Airlines)

Popular in

January

Cheapest in

August

Average price

$288
Provider with most accurate pricing for Roanoke-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Roanoke-Indianapolis flights.
Search Deals
From Roanoke to Indiana
Search Deals
One-way flight from Roanoke to Indiana
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($57 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 11, 2026.
Use the filters below to find and compare flights from Roanoke to Indiana that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RoanokeChicago

ROA - ORD

ROAORD

Roanoke

Sat 5/30

6:40 am-7:53 am

Nonstop2h 13m

Chicago O'Hare Intl

Sat 6/6

9:15 pm-12:24 am

Nonstop2h 09m

$229
Quickest round-trip

RoanokeChicago

ROA - ORD

ROAORD

Roanoke

Thu 4/2

6:45 am-7:54 am

Nonstop2h 09m

Chicago O'Hare Intl

Mon 4/6

6:50 am-9:44 am

Nonstop1h 54m

$229

RoanokeChicago

ROA - ORD

ROAORD

Roanoke

Thu 4/9

6:45 am-7:54 am

Nonstop2h 09m

Chicago O'Hare Intl

Mon 4/13

6:50 am-9:44 am

Nonstop1h 54m

$229

RoanokeChicago

ROA - ORD

ROAORD

Roanoke

Thu 5/28

6:40 am-7:53 am

Nonstop2h 13m

Chicago O'Hare Intl

Mon 6/1

6:45 am-9:46 am

Nonstop2h 01m

$229

RoanokeChicago

ROA - ORD

ROAORD

Roanoke

Fri 4/10

7:59 pm-11:43 pm

1 stop4h 44m

Chicago O'Hare Intl

Sun 4/12

10:30 am-1:29 pm

Nonstop1h 59m

$239

RoanokeChicago

ROA - ORD

ROAORD

Roanoke

Thu 4/9

7:51 pm-11:54 pm

1 stop5h 03m

Chicago O'Hare Intl

Mon 4/13

5:15 am-10:28 am

1 stop4h 13m

$249

RoanokeChicago

ROA - ORD

ROAORD

Roanoke

Sat 4/4

7:59 pm-11:43 pm

1 stop4h 44m

Chicago O'Hare Intl

Wed 4/8

8:45 am-2:13 pm

1 stop4h 28m

$249

RoanokeCincinnati

ROA - CVG

ROACVG

Roanoke

Fri 4/24

8:00 pm-11:56 pm

1 stop3h 56m

Cincinnati Cinci./N. Kentucky

Sun 4/26

7:46 pm-12:10 am

1 stop4h 24m

$259

RoanokeCincinnati

ROA - CVG

ROACVG

Roanoke

Tue 8/4

7:50 pm-11:55 pm

1 stop4h 05m

Cincinnati Cinci./N. Kentucky

Tue 8/11

5:50 pm-11:50 pm

1 stop6h 00m

$259

RoanokeCincinnati

ROA - CVG

ROACVG

Roanoke

Fri 8/14

6:15 am-10:25 am

1 stop4h 10m

Cincinnati Cinci./N. Kentucky

Sat 8/15

10:21 am-2:18 pm

1 stop3h 57m

$259

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/9

Showing 1-10 of 54 resultsSorted by cheapest first
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Best time to book a flight from Roanoke to Indiana

Have a flexible travel schedule? Discover the best time to fly to Indiana from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to Indiana

What is the cheapest month to book a flight from Roanoke to Indiana?

Currently, April is the cheapest month in which you can book a flight from Roanoke to Indiana (average of $209). Flying from Roanoke to Indiana in December is currently the most expensive (average of $255). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Indiana

Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated March 11, 2026.
Read reviews from past customers who have flown Delta,United Airlines, andAmerican Airlines from Roanoke to Indiana. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,278 reviews

Crew

8.5

Entertainment

7.8

Overall

7.9

Comfort

7.9

Boarding

8.1

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,278 reviews
Delta
7.9
Good
8,278 reviews

Crew

8.5

Entertainment

7.8

Overall

7.9

Comfort

7.9

Boarding

8.1

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,414 reviews
Delta
7.9
Good
8,278 reviews

Crew

8.5

Entertainment

7.8

Overall

7.9

Comfort

7.9

Boarding

8.1

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,419 reviews
Delta
7.9
Good
8,278 reviews

Crew

8.5

Entertainment

7.8

Overall

7.9

Comfort

7.9

Boarding

8.1

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Roanoke to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Roanoke to Indiana?

    If you book a flight to Indiana from Roanoke, you will be flying from Roanoke, which is the city’s only airport. Roanoke (ROA) is located 4.2 mi from the center of Roanoke.

  • How long is the flight from Roanoke to Indiana?

    A quick flight from Roanoke to Indiana can take about 2h 13m. United Airlines provides one of the quickest options available for as low as $229. Airlines will cover a distance of 530 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Roanoke to Indiana?

    The most popular route from Roanoke to Indiana is Roanoke - Chicago O'Hare Intl. You may also consider Roanoke - Chicago Midway or Roanoke - Indianapolis.

  • Can I find deals for flights from Roanoke to Indiana that include hotel bookings?

    Yes. In addition to deals on Roanoke to Indiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to Indiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to Indiana.

  • Can I find deals for business class flights from Roanoke to Indiana?

    Yes. Cheapflights offers flight deals from Roanoke to Indiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Roanoke to Indiana?

    Currently, April is the cheapest month in which you can book a flight from Roanoke to Indiana (average of $209). Flying from Roanoke to Indiana in December is currently the most expensive (average of $255). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Roanoke to Indiana

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Roanoke to Indiana

Discover the top 3 airlines that operate flights from Roanoke to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 11, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$228Average$290FlexibilityNo cancel feeOn-time71%
DeltaCheapest$228Average$278FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$229Average$348FlexibilityNo cancel feeOn-time69%

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