HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Indiana

$156+ Cheap flights from Roanoke (ROA) to Indiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/12. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — IND
Aug 20 — Aug 271
Thu 8/20
Thu 8/27
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Roanoke to Indiana with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Roanoke to Indiana

Cheapest flights from Roanoke to Indiana
Explore the most affordable flight options available from Roanoke to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 21, 2026.

This United Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/215:50 pm
ROA
-
ORD
Nonstop2h 08m
United Airlines
Sat 8/296:29 am
ORD
-
ROA
Nonstop2h 12m
United Airlines
Deal found 7/15$269
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/135:35 pm
ROA
-
ORD
Nonstop2h 23m
American Airlines
Sun 8/162:09 pm
ORD
-
ROA
Nonstop1h 56m
American Airlines
Deal found 7/19$270
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/145:35 pm
ROA
-
CVG
1 stop6h 52m
American Airlines
Sun 8/1612:34 pm
CVG
-
ROA
1 stop4h 31m
American Airlines
Deal found 7/19$279
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:47 pm
ROA
-
ORD
Nonstop2h 27m
American Airlines
Sat 9/1911:40 am
ORD
-
ROA
1 stop7h 49m
American Airlines
Deal found 7/19$279
This Delta deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/66:00 am
ROA
-
MDW
1 stop5h 10m
Delta
Tue 9/155:11 pm
MDW
-
ROA
1 stop5h 48m
Delta
Deal found 7/16$289
This Delta deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/183:32 pm
ROA
-
SBN
1 stop6h 08m
Delta
Mon 9/215:03 pm
SBN
-
ROA
1 stop6h 56m
Delta
Deal found 7/20$289
This Delta deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:40 pm
ROA
-
IND
1 stop4h 42m
Delta
Mon 9/286:40 pm
IND
-
ROA
1 stop5h 19m
Delta
Deal found 7/16$289
This Delta deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/17:00 am
ROA
-
CVG
1 stop5h 38m
Delta
Fri 8/75:40 am
CVG
-
ROA
1 stop4h 57m
Delta
Deal found 7/17$294
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/154:49 pm
ROA
-
ORD
Nonstop2h 26m
American Airlines
Mon 10/196:40 am
ORD
-
ROA
1 stop6h 07m
American Airlines
Deal found 7/19$299
This Delta deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1911:18 am
ROA
-
IND
1 stop4h 01m
Delta
Sun 8/236:00 am
IND
-
ROA
1 stop4h 37m
Delta
Deal found 7/21$299
This Delta deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/124:45 pm
ROA
-
MDW
1 stop7h 00m
Delta
Tue 9/155:11 pm
MDW
-
ROA
1 stop5h 48m
Delta
Deal found 7/16$300
This United Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/88:05 pm
ROA
-
ORD
1 stop4h 27m
United Airlines
Sat 10/106:55 am
ORD
-
ROA
Nonstop2h 07m
United Airlines
Deal found 7/15$302

Find flight deals from Roanoke to Indiana

Keep the following information in mind while searching for Roanoke to Indiana flight deals. Data was last updated July 21, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$269
(United Airlines)

One-way from

$156
(Delta)

Popular in

May

Cheapest in

February

Average price

$338
Provider with most accurate pricing for Roanoke-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Roanoke-Indianapolis flights.
Search Deals
From Roanoke to Indiana
Search Deals
One-way flight from Roanoke to Indiana
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($118 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($32 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 21, 2026.
Use the filters below to find and compare flights from Roanoke to Indiana that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RoanokeCincinnati

ROA - CVG

ROACVG

Roanoke

Fri 8/14

5:35 pm-12:27 am

1 stop6h 52m

Cincinnati Cinci./N. Kentucky

Sun 8/16

12:34 pm-5:05 pm

1 stop4h 31m

$279

RoanokeChicago

ROA - MDW

ROAMDW

Roanoke

Thu 12/3

6:00 am-9:52 am

1 stop4h 52m

Chicago Midway

Mon 12/7

1:05 pm-7:13 pm

1 stop5h 08m

$289

RoanokeIndianapolis

ROA - IND

ROAIND

Roanoke

Wed 8/19

3:00 pm-7:02 pm

1 stop4h 02m

Indianapolis

Tue 8/25

2:00 pm-8:59 pm

1 stop6h 59m

$289

RoanokeSouth Bend

ROA - SBN

ROASBN

Roanoke

Fri 9/18

3:30 pm-9:40 pm

1 stop6h 10m

South Bend/Michiana

Mon 9/21

11:48 am-5:52 pm

1 stop6h 04m

$289

RoanokeIndianapolis

ROA - IND

ROAIND

Roanoke

Fri 9/25

6:32 pm-11:22 pm

1 stop4h 50m

Indianapolis

Mon 9/28

6:38 pm-11:59 pm

1 stop5h 21m

$289

RoanokeCincinnati

ROA - CVG

ROACVG

Roanoke

Sat 8/1

7:00 am-12:38 pm

1 stop5h 38m

Cincinnati Cinci./N. Kentucky

Fri 8/7

5:40 am-10:37 am

1 stop4h 57m

$294

RoanokeIndianapolis

ROA - IND

ROAIND

Roanoke

Thu 8/20

7:59 pm-12:27 am

1 stop4h 28m

Indianapolis

Wed 8/26

8:05 am-2:51 pm

1 stop6h 46m

$299

RoanokeIndianapolis

ROA - IND

ROAIND

Roanoke

Thu 8/6

6:15 am-10:20 am

1 stop4h 05m

Indianapolis

Sat 8/8

12:19 pm-4:55 pm

1 stop4h 36m

$304

RoanokeCincinnati

ROA - CVG

ROACVG

Roanoke

Thu 10/8

11:13 am-5:21 pm

1 stop6h 08m

Cincinnati Cinci./N. Kentucky

Sun 10/11

7:59 pm-12:28 am

1 stop4h 29m

$304

RoanokeSouth Bend

ROA - SBN

ROASBN

Roanoke

Fri 7/31

5:52 pm-11:23 pm

1 stop5h 31m

South Bend/Michiana

Tue 8/4

4:41 pm-9:03 pm

1 stop4h 22m

$319

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/17

Showing 1-10 of 50 resultsSorted by cheapest first
1
2
3
...
5

Best time to book a flight from Roanoke to Indiana

Have a flexible travel schedule? Discover the best time to fly to Indiana from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to Indiana

What is the cheapest month to book a flight from Roanoke to Indiana?

Currently, February is the cheapest month in which you can book a flight from Roanoke to Indiana (average of $288). Flying from Roanoke to Indiana in May is currently the most expensive (average of $749). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Roanoke to Indiana?

Reviews of airlines servicing Indiana

Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated July 21, 2026.
Read reviews from past customers who have flown United Airlines and American Airlines from Roanoke to Indiana. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
10,011 reviews

Boarding

7.7

Comfort

7.3

Overall

7.4

Crew

8.1

Entertainment

7.1

Food

6.7

Reviews

1 / 20
6.0
Good

ROHIT,Jun 2026

IND - EWR

It should not be delayed by 2 hours. I missed the important event due to this
United Airlines
7.4
Good
10,011 reviews
United Airlines
7.4
Good
10,011 reviews

Boarding

7.7

Comfort

7.3

Overall

7.4

Crew

8.1

Entertainment

7.1

Food

6.7

Reviews

1 / 20
6.0
Good

ROHIT,Jun 2026

IND - EWR

It should not be delayed by 2 hours. I missed the important event due to this
American Airlines
7.1
Good
11,832 reviews
United Airlines
7.4
Good
10,011 reviews

Boarding

7.7

Comfort

7.3

Overall

7.4

Crew

8.1

Entertainment

7.1

Food

6.7

Reviews

1 / 20
6.0
Good

ROHIT,Jun 2026

IND - EWR

It should not be delayed by 2 hours. I missed the important event due to this

Related info for your journey

Find useful and relevant information for your journey from Roanoke to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Roanoke to Indiana?

    If you book a flight to Indiana from Roanoke, you will be flying from Roanoke, which is the city’s only airport. Roanoke (ROA) is located 4.2 mi from the center of Roanoke.

  • How long is the flight from Roanoke to Indiana?

    A quick flight from Roanoke to Indiana can take about 4h 02m. American Airlines provides one of the quickest options available for as low as $289. Airlines will cover a distance of 379 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Roanoke to Indiana?

    The most popular route from Roanoke to Indiana is Roanoke - Chicago O'Hare Intl. You may also consider Roanoke - Chicago Midway or Roanoke - Indianapolis.

  • Can I find deals for flights from Roanoke to Indiana that include hotel bookings?

    Yes. In addition to deals on Roanoke to Indiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to Indiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to Indiana.

  • Can I find deals for business class flights from Roanoke to Indiana?

    Yes. Cheapflights offers flight deals from Roanoke to Indiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Roanoke to Indiana?

    Currently, February is the cheapest month in which you can book a flight from Roanoke to Indiana (average of $288). Flying from Roanoke to Indiana in May is currently the most expensive (average of $749). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Roanoke to Indiana

See prices for flight routes from nearby airports that may be better suited for you.
Dulles Intl to Dallas/Fort Worth flights
Dulles Intl to Seattle flights
Dulles Intl to Las Vegas flights
Reagan-National to Seattle flights
Dulles Intl to Orlando flights
Dulles Intl to Miami flights
Reagan-National to Dallas/Fort Worth flights
Reagan-National to O'Hare Intl flights
Reagan-National to Miami flights
Reagan-National to Los Angeles flights
Dulles Intl to O'Hare Intl flights
Reagan-National to Orlando flights
Reagan-National to Boston flights
Reagan-National to Las Vegas flights
Dulles Intl to San Francisco flights
Dulles Intl to Los Angeles flights
Dulles Intl to Boston flights
Dulles Intl to Fort Lauderdale flights
Dulles Intl to Atlanta flights
Dulles Intl to Hobby flights
Reagan-National to San Francisco flights
Dulles Intl to Denver flights
Raleigh to John F Kennedy Intl flights
Raleigh to Boston flights
Raleigh to Newark flights
Raleigh to LaGuardia flights
Dulles Intl to Midway flights
Reagan-National to Atlanta flights
Dulles Intl to Tampa flights
Raleigh to Seattle flights
Reagan-National to Hobby flights
Raleigh to O'Hare Intl flights
Raleigh to Dallas/Fort Worth flights
Raleigh to Miami flights
Reagan-National to Fort Lauderdale flights
Reagan-National to Nashville flights
Dulles Intl to Sky Harbor Intl flights
Dulles Intl to George Bush Intcntl flights
Reagan-National to Minneapolis flights
Raleigh to Denver flights
Dulles Intl to New Orleans flights
Raleigh to Las Vegas flights
Dulles Intl to Austin flights
Reagan-National to Tampa flights
Reagan-National to Denver flights
Raleigh to Hobby flights
Reagan-National to George Bush Intcntl flights
Dulles Intl to San Diego flights
Raleigh to Orlando flights
Reagan-National to New Orleans flights

Top 2 airlines flying from Roanoke to Indiana

Discover the top 2 airlines that operate flights from Roanoke to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 21, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$228Average$601FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$233Average$376FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.