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$134+ Cheap flights from Roanoke (ROA) to Indiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/21. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — IND
Sep 3 — Sep 101
Thu 9/3
Thu 9/10
1 adult, Economy
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Cheap flight deals from Roanoke to Indiana

Cheapest flights from Roanoke to Indiana
Explore the most affordable flight options available from Roanoke to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 4, 2026.

This United Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:51 pm
ROA
-
ORD
Nonstop2h 09m
United Airlines
Sun 10/186:55 am
ORD
-
ROA
Nonstop2h 02m
United Airlines
Deal found 8/1$279
This Delta deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:38 pm
ROA
-
CVG
1 stop4h 07m
Delta
Thu 10/227:59 pm
CVG
-
ROA
1 stop4h 28m
Delta
Deal found 8/1$289
This United Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/178:05 pm
ROA
-
ORD
1 stop4h 35m
United Airlines
Mon 9/216:57 am
ORD
-
ROA
Nonstop2h 02m
United Airlines
Deal found 8/1$289
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/293:00 pm
ROA
-
DAY
1 stop4h 03m
United Airlines
Mon 8/317:48 pm
DAY
-
ROA
1 stop3h 55m
United Airlines
Deal found 7/31$289
This American Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:47 pm
ROA
-
ORD
Nonstop2h 27m
American Airlines
Sun 10/46:29 am
ORD
-
ROA
1 stop6h 22m
American Airlines
Deal found 8/1$290
This United Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:49 am
ROA
-
ORD
Nonstop2h 11m
United Airlines
Mon 10/197:45 pm
ORD
-
ROA
Nonstop2h 14m
United Airlines
Deal found 8/2$292
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/1410:12 am
ROA
-
ORD
1 stop13h 47m
Multiple Airlines
Sat 9/196:20 am
ORD
-
ROA
2 stops26h 41m
Multiple Airlines
Deal found 7/30$298
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:32 pm
ROA
-
ORD
1 stop6h 27m
Delta
Wed 9/236:25 pm
ORD
-
ROA
1 stop4h 34m
Delta
Deal found 8/3$299
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:32 pm
ROA
-
MDW
1 stop5h 12m
Delta
Sat 9/264:30 pm
MDW
-
ROA
1 stop4h 21m
Delta
Deal found 8/3$299
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:32 pm
ROA
-
IND
1 stop4h 50m
Delta
Mon 9/286:38 pm
IND
-
ROA
1 stop5h 21m
Delta
Deal found 8/3$299
This United Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:40 am
ROA
-
SBN
1 stop5h 50m
United Airlines
Sat 8/299:55 am
SBN
-
ROA
1 stop4h 23m
United Airlines
Deal found 8/1$299
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/185:35 pm
ROA
-
ORD
Nonstop2h 23m
American Airlines
Sun 8/232:09 pm
ORD
-
ROA
Nonstop1h 56m
American Airlines
Deal found 7/30$301

Find flight deals from Roanoke to Indiana

Keep the following information in mind while searching for Roanoke to Indiana flight deals. Data was last updated August 4, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$279
(United Airlines)

One-way from

$134
(Kiwi.com)

Popular in

May

Cheapest in

February

Average price

$429
Provider with most accurate pricing for Roanoke-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Roanoke-Indianapolis flights.
Search Deals
From Roanoke to Indiana
Search Deals
One-way flight from Roanoke to Indiana
Search Deals
Highest demand for flights based on searches. 21% potential increase in price ($116 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($31 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in August 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 4, 2026.
Use the filters below to find and compare flights from Roanoke to Indiana that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

RoanokeChicago

ROA - ORD

ROAORD

Roanoke

Thu 8/27

6:40 am-7:51 am

Nonstop2h 11m

Chicago O'Hare Intl

Thu 9/3

2:00 pm-5:09 pm

Nonstop2h 09m

$279

RoanokeCincinnati

ROA - CVG

ROACVG

Roanoke

Tue 10/13

6:00 am-12:35 pm

1 stop6h 35m

Cincinnati Cinci./N. Kentucky

Tue 10/20

6:00 am-10:32 am

1 stop4h 32m

$289

RoanokeCincinnati

ROA - CVG

ROACVG

Roanoke

Fri 12/4

6:00 am-11:07 am

1 stop5h 07m

Cincinnati Cinci./N. Kentucky

Mon 12/7

12:00 pm-6:09 pm

1 stop6h 09m

$289

RoanokeDayton

ROA - DAY

ROADAY

Roanoke

Sat 8/29

3:00 pm-7:03 pm

1 stop4h 03m

Dayton

Mon 8/31

7:48 pm-11:43 pm

1 stop3h 55m

$289

RoanokeCincinnati

ROA - CVG

ROACVG

Roanoke

Wed 10/14

11:12 am-5:24 pm

1 stop6h 12m

Cincinnati Cinci./N. Kentucky

Sat 10/17

6:00 am-10:32 am

1 stop4h 32m

$289

RoanokeCincinnati

ROA - CVG

ROACVG

Roanoke

Mon 10/12

6:38 pm-10:45 pm

1 stop4h 07m

Cincinnati Cinci./N. Kentucky

Thu 10/22

7:59 pm-12:27 am

1 stop4h 28m

$289

RoanokeIndianapolis

ROA - IND

ROAIND

Roanoke

Sat 9/19

6:15 am-10:15 am

1 stop4h 00m

Indianapolis

Mon 9/21

2:00 pm-8:54 pm

1 stop6h 54m

$299

RoanokeChicago

ROA - MDW

ROAMDW

Roanoke

Fri 11/13

6:00 am-12:05 pm

1 stop7h 05m

Chicago Midway

Mon 11/16

11:28 am-6:09 pm

1 stop5h 41m

$299

RoanokeChicago

ROA - MDW

ROAMDW

Roanoke

Wed 12/2

6:54 pm-10:56 pm

1 stop5h 02m

Chicago Midway

Mon 12/7

1:00 pm-6:09 pm

1 stop4h 09m

$299

RoanokeIndianapolis

ROA - IND

ROAIND

Roanoke

Fri 9/25

6:32 pm-11:22 pm

1 stop4h 50m

Indianapolis

Mon 9/28

6:38 pm-11:59 pm

1 stop5h 21m

$299

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/30

Showing 1-10 of 60 resultsSorted by cheapest first
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6

Best time to book a flight from Roanoke to Indiana

Have a flexible travel schedule? Discover the best time to fly to Indiana from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to Indiana

What is the cheapest month to book a flight from Roanoke to Indiana?

Currently, February is the cheapest month in which you can book a flight from Roanoke to Indiana (average of $288). Flying from Roanoke to Indiana in May is currently the most expensive (average of $749). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Indiana

Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated August 4, 2026.
Read reviews from past customers who have flown United Airlines and American Airlines from Roanoke to Indiana. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
10,059 reviews

Entertainment

7.1

Crew

8.1

Food

6.6

Overall

7.4

Boarding

7.7

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Dawn,Aug 2026

ORD - DEN

I missed my connecting flight because our plane took off ten minutes late and then when we got to the airport another plane was in our shoot waiting to get fueled up and that took 30 minutes so I missed my connecting flight. I asked if I could get off and they assured me the plane would most likely wait for me since they know what time the planes get in because of an app. I was not happy. I had to wait till 7:25 to board the next flight and then that was delayed. Gates changed till 9:20. Terrible
United Airlines
7.4
Good
10,059 reviews
United Airlines
7.4
Good
10,059 reviews

Entertainment

7.1

Crew

8.1

Food

6.6

Overall

7.4

Boarding

7.7

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Dawn,Aug 2026

ORD - DEN

I missed my connecting flight because our plane took off ten minutes late and then when we got to the airport another plane was in our shoot waiting to get fueled up and that took 30 minutes so I missed my connecting flight. I asked if I could get off and they assured me the plane would most likely wait for me since they know what time the planes get in because of an app. I was not happy. I had to wait till 7:25 to board the next flight and then that was delayed. Gates changed till 9:20. Terrible
American Airlines
7.1
Good
11,845 reviews
United Airlines
7.4
Good
10,059 reviews

Entertainment

7.1

Crew

8.1

Food

6.6

Overall

7.4

Boarding

7.7

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Dawn,Aug 2026

ORD - DEN

I missed my connecting flight because our plane took off ten minutes late and then when we got to the airport another plane was in our shoot waiting to get fueled up and that took 30 minutes so I missed my connecting flight. I asked if I could get off and they assured me the plane would most likely wait for me since they know what time the planes get in because of an app. I was not happy. I had to wait till 7:25 to board the next flight and then that was delayed. Gates changed till 9:20. Terrible

Related info for your journey

Find useful and relevant information for your journey from Roanoke to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Roanoke to Indiana?

    If you book a flight to Indiana from Roanoke, you will be flying from Roanoke, which is the city’s only airport. Roanoke (ROA) is located 4.2 mi from the center of Roanoke.

  • How long is the flight from Roanoke to Indiana?

    A quick flight from Roanoke to Indiana can take about 2h 11m. United Airlines provides one of the quickest options available for as low as $279. Airlines will cover a distance of 530 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Roanoke to Indiana?

    The most popular route from Roanoke to Indiana is Roanoke - Chicago O'Hare Intl. You may also consider Roanoke - Chicago Midway or Roanoke - Indianapolis.

  • Can I find deals for flights from Roanoke to Indiana that include hotel bookings?

    Yes. In addition to deals on Roanoke to Indiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to Indiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to Indiana.

  • Can I find deals for business class flights from Roanoke to Indiana?

    Yes. Cheapflights offers flight deals from Roanoke to Indiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Roanoke to Indiana?

    Currently, February is the cheapest month in which you can book a flight from Roanoke to Indiana (average of $288). Flying from Roanoke to Indiana in May is currently the most expensive (average of $749). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from Roanoke to Indiana

Discover the top 2 airlines that operate flights from Roanoke to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 4, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$228Average$590FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$233Average$376FlexibilityNo cancel feeOn-time69%

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