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$49+ Cheap flights from Missouri to Indiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/17. Fares are subject to change and may not be available on all flights or dates of travel.
STL — IND
dic. 6 — dic. 131
sáb. 12/6
sáb. 12/13
1 adult, Economy
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Cheap flight deals from Missouri to Indiana

Keep the following information in mind while searching for Missouri to Indiana flight deals. Data was last updated noviembre 6, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$97
(United Airlines)

One-way from

$49
(Southwest)

Popular in

March

Cheapest in

April

Average price

$557
Provider with most accurate pricing for Lambert-St Louis-Indianapolis flight deals.
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Provider most trusted by Cheapflights users for Lambert-St Louis-Indianapolis flights.
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From Missouri to Indiana
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One-way flight from Missouri to Indiana
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Highest demand for flights based on searches. 3% potential increase in price ($12 potential increase over avg. RT price).
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Cheapest flight prices on average. 7% potential price decrease ($25 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Missouri to Indiana

Cheapest flights from Missouri to Indiana
Explore the most affordable flight options available from Missouri to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on noviembre 6, 2025.

This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/258:05 amSTL - ORD
Nonstop1h 35mUnited Airlines
jue. 1/15:50 pmORD - STL
Nonstop1h 28mUnited Airlines
Deal found 11/4$97
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/55:27 pmSTL - ORD
Nonstop1h 23mUnited Airlines
dom. 12/71:00 pmORD - STL
Nonstop1h 25mUnited Airlines
Deal found 11/5$101
This Frontier deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/412:04 pmSTL - MDW
1 stop10h 08mFrontier
lun. 12/83:10 pmMDW - STL
1 stop7h 23mFrontier
Deal found 11/6$110
This Frontier deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/412:04 pmSTL - ORD
1 stop5h 23mFrontier
lun. 12/82:26 pmORD - STL
1 stop8h 07mFrontier
Deal found 11/6$110
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/1112:04 pmSTL - ORD
1 stop5h 23mFrontier
mié. 12/2412:39 pmORD - STL
1 stop21h 01mFrontier
Deal found 11/6$112
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/35:05 amSTL - ORD
Nonstop1h 30mAmerican Airlines
mié. 12/103:23 pmORD - STL
Nonstop1h 27mAmerican Airlines
Deal found 11/5$117
This Booking.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/48:09 pmMCI - IND
1 stop22h 44mFrontier
jue. 12/117:19 pmIND - MCI
1 stop19h 34mFrontier
Deal found 11/4$121
This Southwest deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/178:25 amSTL - ORD
1 stop3h 50mSouthwest
mar. 1/61:45 pmORD - STL
1 stop5h 00mSouthwest
Deal found 11/6$121
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/412:04 pmSTL - ORD
1 stop5h 23mFrontier
vie. 12/57:00 amORD - STL
1 stop27h 14mFrontier
Deal found 11/6$129
This Frontier deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/1112:04 pmSTL - ORD
1 stop5h 23mFrontier
lun. 12/152:26 pmORD - STL
1 stop8h 07mFrontier
Deal found 11/6$130
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/1112:04 pmSTL - MDW
1 stop6h 04mFrontier
dom. 12/146:15 amMDW - STL
1 stop27h 37mFrontier
Deal found 11/5$135
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/1410:42 amSTL - ORD
1 stop11h 42mFrontier
vie. 1/97:51 pmORD - STL
1 stop14h 11mFrontier
Deal found 11/6$141

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 6, 2025.
Use the filters below to find and compare flights from Missouri to Indiana that are best for you.

Fly from

Missouri

Fly to

Indiana

Route

Depart

Return

Price

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

jue. 12/25

8:05 am-9:40 am

Nonstop1h 35m

Chicago O'Hare Intl

jue. 1/1

5:50 pm-7:18 pm

Nonstop1h 28m

$97

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

dom. 12/7

5:15 am-6:39 am

Nonstop1h 24m

Chicago O'Hare Intl

jue. 12/11

1:22 pm-2:50 pm

Nonstop1h 28m

$101

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

mar. 12/16

8:25 am-12:15 pm

1 stop3h 50m

Chicago O'Hare Intl

mar. 12/16

2:15 pm-9:35 pm

1 stop7h 20m

$137

St. LouisChicago

STL - MDW

STLMDW

Lambert-St Louis

mar. 12/16

1:50 pm-2:55 pm

Nonstop1h 05m

Chicago Midway

sáb. 1/10

9:50 am-5:00 pm

1 stop7h 10m

$154

St. LouisChicago

STL - MDW

STLMDW

Lambert-St Louis

lun. 1/5

6:35 am-12:48 pm

1 stop6h 13m

Chicago Midway

mar. 1/13

7:16 pm-11:25 pm

1 stop4h 09m

$157

St. LouisChicago

STL - MDW

STLMDW

Lambert-St Louis

mié. 12/3

5:28 pm-11:47 pm

1 stop6h 19m

Chicago Midway

mié. 12/10

10:49 am-4:21 pm

1 stop5h 32m

$157

St. LouisChicago

STL - MDW

STLMDW

Lambert-St Louis

vie. 12/5

7:02 pm-11:47 pm

1 stop4h 45m

Chicago Midway

vie. 12/12

7:02 pm-11:29 pm

1 stop4h 27m

$157

St. LouisChicago

STL - MDW

STLMDW

Lambert-St Louis

jue. 12/11

7:00 am-8:10 am

Nonstop1h 10m

Chicago Midway

lun. 12/15

11:25 am-12:35 pm

Nonstop1h 10m

$157

St. LouisChicago

STL - MDW

STLMDW

Lambert-St Louis

vie. 12/5

5:12 pm-11:47 pm

1 stop6h 35m

Chicago Midway

dom. 12/7

6:00 am-10:45 am

1 stop4h 45m

$157

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

vie. 12/5

2:38 pm-6:27 pm

1 stop3h 49m

Chicago O'Hare Intl

dom. 12/7

5:30 am-10:45 am

1 stop5h 15m

$157

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/5

Showing 1-10 of 60 results
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Best time to book a flight from Missouri to Indiana

Have a flexible travel schedule? Discover the best time to fly to Indiana from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Indiana

What is the cheapest month to book a flight from Missouri to Indiana?

Currently, August is the cheapest month in which you can book a flight from Missouri to Indiana (average of $161). Flying from Missouri to Indiana in June is currently the most expensive (average of $244). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to IN?

Find hourly flight availability from Missouri to Indiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated noviembre 6, 2025.

A simple way to save on the total cost of your ticket is to fly from Missouri to Indiana in the evening. If you’re flexible enough to do this you can expect to save up to 50% on your trip compared to booking a flight in the morning.

Reviews of airlines servicing Indiana

Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated noviembre 6, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from Missouri to Indiana by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,241 reviews

Crew

8.6

Food

7.0

Overall

8.0

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,241 reviews
Southwest
8.0
Very good
4,241 reviews

Crew

8.6

Food

7.0

Overall

8.0

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
8,001 reviews
Southwest
8.0
Very good
4,241 reviews

Crew

8.6

Food

7.0

Overall

8.0

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
9,007 reviews
Southwest
8.0
Very good
4,241 reviews

Crew

8.6

Food

7.0

Overall

8.0

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,040 reviews
Southwest
8.0
Very good
4,241 reviews

Crew

8.6

Food

7.0

Overall

8.0

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Missouri to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Indiana?

    There are many flights that can get you from Missouri to Indiana in 1h 24m. Fly via United Airlines, American Airlines, or Southwest to get the fastest option. There are 258 mi between Missouri and Indiana. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Missouri to Indiana one-way?

    One-way options have recently been found by users for as low as $49 on Southwest. Other airlines that offer cheap prices include United Airlines from $49 and Frontier from $95 one-way.

  • Can I find deals for flights from Missouri to Indiana that include hotel bookings?

    Yes. In addition to deals on Missouri to Indiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Indiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Indiana.

  • Can I find deals for business class flights from Missouri to Indiana?

    Yes. Cheapflights offers flight deals from Missouri to Indiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Indiana?

    Currently, August is the cheapest month in which you can book a flight from Missouri to Indiana (average of $161). Flying from Missouri to Indiana in June is currently the most expensive (average of $244). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Missouri to Indiana

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Missouri to Indiana

Discover the top 4 airlines that operate flights from Missouri to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$178Average$376FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$204Average$346FlexibilityNo cancel feeOn-time63%
DeltaCheapest$216Average$363FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$218Average$380FlexibilityNo cancel feeOn-time69%

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