$40+ Cheap flights from Missouri to Indiana
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/18. Fares are subject to change and may not be available on all flights or dates of travel.
STL — IND
Mar 5 — Mar 121
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Missouri to IndianaExplore the most affordable flight options available from Missouri to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.
Explore the most affordable flight options available from Missouri to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.
This Southwest deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/63:55 pm
STL
- MDW
Nonstop1h 10m
Southwest
Wed 5/138:15 am
MDW
- STL
Nonstop1h 15m
Southwest
Deal found 2/3![Southwest logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/33:49 pm
STL
- ORD
1 stop24h 03m
Frontier
Tue 3/107:41 pm
ORD
- STL
1 stop14h 56m
Frontier
Deal found 2/3![Frontier logo]()
$118
This Southwest deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/61:45 pm
STL
- MDW
Nonstop1h 10m
Southwest
Wed 5/65:30 pm
MDW
- STL
1 stop5h 40m
Southwest
Deal found 2/3![Southwest logo]()
$127
This Southwest deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/26:55 pm
STL
- MDW
Nonstop1h 10m
Southwest
Tue 5/510:15 am
MDW
- STL
Nonstop1h 15m
Southwest
Deal found 2/3![Southwest logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/2310:55 am
MCI
- IND
1 stop6h 36m
Frontier
Thu 2/267:27 pm
IND
- MCI
1 stop15h 29m
Frontier
Deal found 2/2![Frontier logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2711:00 am
MCI
- CVG
1 stop5h 32m
Frontier
Sun 3/11:07 pm
CVG
- MCI
1 stop21h 46m
Frontier
Deal found 2/1![Frontier logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/61:09 pm
STL
- MDW
1 stop6h 38m
Frontier
Fri 3/136:05 am
MDW
- STL
1 stop7h 29m
Frontier
Deal found 2/2![Frontier logo]()
$162
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/61:09 pm
STL
- ORD
1 stop9h 30m
Frontier
Fri 3/135:01 am
ORD
- STL
1 stop8h 33m
Frontier
Deal found 2/2![Frontier logo]()
$165
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/278:22 pm
STL
- MDW
2 stops18h 57m
Frontier
Sun 3/19:04 pm
MDW
- STL
1 stop9h 47m
Frontier
Deal found 2/2![Frontier logo]()
$167
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/208:20 pm
STL
- ORD
1 stop14h 26m
Multiple Airlines
Mon 2/236:51 pm
ORD
- STL
2 stops36h 00m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$169
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2511:15 am
COU
- ORD
Nonstop1h 30m
United Airlines
Sun 3/19:00 am
ORD
- COU
Nonstop1h 33m
United Airlines
Deal found 2/1![United Airlines logo]()
$179
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/48:17 pm
STL
- ORD
1 stop14h 34m
Multiple Airlines
Thu 3/57:23 pm
ORD
- STL
2 stops16h 26m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$180
Best flights from Missouri to IndianaDiscover carefully curated flight deals from Missouri to Indiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 3, 2026.
Discover carefully curated flight deals from Missouri to Indiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/2310:55 am
MCI
- IND
1 stop6h 36m
Frontier
Thu 2/267:27 pm
IND
- MCI
1 stop15h 29m
Frontier
Deal found 2/2![Frontier logo]()
$151
This Southwest deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/26:55 pm
STL
- MDW
Nonstop1h 10m
Southwest
Tue 5/52:35 pm
MDW
- STL
1 stop5h 25m
Southwest
Deal found 2/3![Southwest logo]()
$154
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/33:10 pm
COU
- ORD
Nonstop1h 30m
United Airlines
Tue 3/109:00 am
ORD
- COU
Nonstop1h 33m
United Airlines
Deal found 2/1![United Airlines logo]()
$179
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2611:26 am
MCI
- CVG
1 stop23h 33m
Multiple Airlines
Sun 3/11:07 pm
CVG
- MCI
1 stop21h 46m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$203
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/167:34 am
SGF
- ORD
Nonstop1h 51m
American Airlines
Fri 2/278:00 am
ORD
- SGF
Nonstop1h 50m
American Airlines
Deal found 2/2![American Airlines logo]()
$204
This Delta deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/25:32 pm
SGF
- ORD
1 stop6h 24m
Delta
Mon 3/911:10 am
ORD
- SGF
1 stop7h 01m
Delta
Deal found 1/31![Delta logo]()
$209
This CheapOair deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/611:26 am
MCI
- IND
1 stop6h 57m
Spirit Airlines
Sun 3/88:18 pm
IND
- MCI
1 stop15h 12m
Spirit Airlines
Deal found 2/3![Spirit Airlines logo]()
$274
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2711:00 am
MCI
- CVG
1 stop5h 32m
Frontier
Sun 3/11:07 pm
CVG
- MCI
1 stop21h 46m
Frontier
Deal found 2/1![Frontier logo]()
$160
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2511:15 am
COU
- ORD
Nonstop1h 30m
United Airlines
Sun 3/19:00 am
ORD
- COU
Nonstop1h 33m
United Airlines
Deal found 2/1![United Airlines logo]()
$179
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/142:41 pm
COU
- ORD
Nonstop1h 28m
United Airlines
Tue 3/179:00 am
ORD
- COU
Nonstop1h 33m
United Airlines
Deal found 2/1![United Airlines logo]()
$179
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/174:55 pm
MCI
- MDW
Nonstop1h 25m
Southwest
Sat 4/187:55 am
MDW
- MCI
Nonstop1h 30m
Southwest
Deal found 2/1![Southwest logo]()
$205
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2011:00 am
MCI
- CVG
1 stop5h 32m
Multiple Airlines
Mon 2/231:07 pm
CVG
- MCI
2 stops27h 22m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$207
This Delta deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/25:32 pm
SGF
- MDW
1 stop4h 59m
Delta
Mon 3/99:35 am
MDW
- SGF
2 stops8h 36m
Delta
Deal found 1/31![Delta logo]()
$214
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/23:23 pm
COU
- ORD
Nonstop1h 33m
United Airlines
Sun 4/51:16 pm
ORD
- COU
Nonstop1h 32m
United Airlines
Deal found 2/1![United Airlines logo]()
$179
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/168:10 pm
STL
- IND
1 stop11h 29m
Frontier
Tue 3/178:33 pm
IND
- STL
1 stop14h 16m
Frontier
Deal found 2/1![Frontier logo]()
$198
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/274:28 pm
COU
- ORD
Nonstop1h 42m
American Airlines
Sat 5/167:56 pm
ORD
- COU
Nonstop1h 34m
American Airlines
Deal found 2/3![American Airlines logo]()
$224
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/78:40 pm
MCI
- ORD
1 stop12h 03m
Multiple Airlines
Tue 3/1012:44 pm
ORD
- MCI
1 stop26h 45m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$209
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/710:37 am
MCI
- ORD
1 stop6h 06m
Delta
Sat 4/1812:14 pm
ORD
- MCI
2 stops8h 31m
Delta
Deal found 2/1![Delta logo]()
$216
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:20 am
MCI
- ORD
1 stop7h 55m
Southwest
Sat 4/182:05 pm
ORD
- MCI
1 stop6h 30m
Southwest
Deal found 2/1![Southwest logo]()
$225
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/46:30 pm
SGF
- ORD
Nonstop1h 48m
United Airlines
Tue 4/73:35 pm
ORD
- SGF
Nonstop1h 49m
United Airlines
Deal found 2/1![United Airlines logo]()
$189
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/2110:37 am
MCI
- ORD
1 stop5h 41m
Delta
Tue 3/247:10 am
ORD
- MCI
2 stops8h 29m
Delta
Deal found 2/1![Delta logo]()
$216
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/193:49 pm
STL
- IND
2 stops25h 42m
Frontier
Sun 2/227:31 pm
IND
- STL
1 stop12h 20m
Frontier
Deal found 2/1![Frontier logo]()
$216
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/78:12 pm
STL
- ORD
1 stop12h 31m
Multiple Airlines
Sun 3/157:17 am
ORD
- STL
2 stops30h 17m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$225
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:00 pm
SGF
- ORD
Nonstop1h 43m
United Airlines
Sat 5/168:45 am
ORD
- SGF
Nonstop1h 51m
United Airlines
Deal found 2/1![United Airlines logo]()
$189
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/78:25 am
MCI
- MDW
1 stop3h 20m
Southwest
Mon 3/911:40 am
MDW
- MCI
Nonstop1h 30m
Southwest
Deal found 2/1![Southwest logo]()
$233
This Mytrip deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/911:26 am
MCI
- IND
1 stop10h 22m
Spirit Airlines
Thu 3/126:00 am
IND
- MCI
3 stops30h 29m
Spirit Airlines
Deal found 2/2![Spirit Airlines logo]()
$286
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/269:24 pm
MCI
- CVG
2 stops12h 48m
Frontier
Sun 3/11:07 pm
CVG
- MCI
1 stop21h 46m
Frontier
Deal found 2/1![Frontier logo]()
$226
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/148:00 pm
SGF
- ORD
Nonstop1h 43m
United Airlines
Sun 5/177:57 pm
ORD
- SGF
Nonstop2h 00m
United Airlines
Deal found 2/1![United Airlines logo]()
$189
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/184:24 pm
MCI
- CVG
2 stops24h 08m
Multiple Airlines
Sun 2/221:07 pm
CVG
- MCI
1 stop21h 46m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$231
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/256:35 am
MCI
- IND
1 stop7h 01m
Delta
Thu 3/268:00 am
IND
- MCI
1 stop6h 30m
Delta
Deal found 2/2![Delta logo]()
$237
Last-minute flights from Missouri to IndianaDiscover last-minute flight deals from Missouri to Indiana. Data last updated February 3, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Indiana. Data last updated February 3, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/208:20 pm
STL
- ORD
1 stop14h 26m
Multiple Airlines
Mon 2/236:51 pm
ORD
- STL
2 stops36h 00m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$169
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/2310:55 am
MCI
- IND
1 stop6h 36m
Frontier
Thu 2/267:27 pm
IND
- MCI
1 stop15h 29m
Frontier
Deal found 2/2![Frontier logo]()
$151
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2511:15 am
COU
- ORD
Nonstop1h 30m
United Airlines
Sun 3/19:00 am
ORD
- COU
Nonstop1h 33m
United Airlines
Deal found 2/1![United Airlines logo]()
$179
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2610:28 am
SGF
- ORD
Nonstop1h 42m
American Airlines
Sat 2/288:10 am
ORD
- SGF
Nonstop1h 50m
American Airlines
Deal found 2/2![American Airlines logo]()
$189
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2711:00 am
MCI
- CVG
1 stop5h 32m
Frontier
Sun 3/11:07 pm
CVG
- MCI
1 stop21h 46m
Frontier
Deal found 2/1![Frontier logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/278:22 pm
STL
- MDW
2 stops18h 57m
Frontier
Sun 3/19:04 pm
MDW
- STL
1 stop9h 47m
Frontier
Deal found 2/2![Frontier logo]()
$167
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/13:49 pm
STL
- IND
1 stop15h 43m
Multiple Airlines
Sun 3/812:16 pm
IND
- STL
1 stop26h 03m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$185
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/33:49 pm
STL
- ORD
1 stop24h 03m
Frontier
Tue 3/107:41 pm
ORD
- STL
1 stop14h 56m
Frontier
Deal found 2/3![Frontier logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/48:17 pm
STL
- ORD
1 stop14h 34m
Multiple Airlines
Thu 3/57:23 pm
ORD
- STL
2 stops16h 26m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$180
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/61:09 pm
STL
- MDW
1 stop6h 38m
Frontier
Fri 3/136:05 am
MDW
- STL
1 stop7h 29m
Frontier
Deal found 2/2![Frontier logo]()
$162
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/61:09 pm
STL
- ORD
1 stop9h 30m
Frontier
Fri 3/135:01 am
ORD
- STL
1 stop8h 33m
Frontier
Deal found 2/2![Frontier logo]()
$165
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/61:09 pm
STL
- ORD
2 stops11h 31m
Multiple Airlines
Fri 3/135:01 am
ORD
- STL
1 stop8h 33m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$185
One-way flights from Missouri to IndianaSearch for one-way flight options from Missouri to Indiana. Find affordable one-way fares based on user searches. Data last updated February 3, 2026.
Search for one-way flight options from Missouri to Indiana. Find affordable one-way fares based on user searches. Data last updated February 3, 2026.
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/185:40 am
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 2/1![Southwest logo]()
$40
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/287:41 am
STL
- ORD
Nonstop1h 29m
United Airlines
Deal found 2/1![United Airlines logo]()
$46
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/2510:35 am
STL
- MDW
1 stop4h 10m
Southwest
Deal found 2/1![Southwest logo]()
$50
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:10 am
STL
- ORD
1 stop5h 20m
Southwest
Deal found 2/1![Southwest logo]()
$50
This Southwest deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/78:45 pm
STL
- MDW
Nonstop1h 05m
Southwest
Deal found 2/3![Southwest logo]()
$59
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/219:10 am
STL
- ORD
Nonstop1h 29m
United Airlines
Deal found 2/3![United Airlines logo]()
$59
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/33:49 pm
STL
- ORD
1 stop24h 03m
Frontier
Deal found 2/1![Frontier logo]()
$60
This Southwest deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2810:30 am
MCI
- MDW
Nonstop1h 25m
Southwest
Deal found 2/2![Southwest logo]()
$67
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/98:22 pm
STL
- MDW
1 stop22h 45m
Frontier
Deal found 2/1![Frontier logo]()
$67
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/48:17 pm
STL
- IND
1 stop21h 14m
Frontier
Deal found 2/2![Frontier logo]()
$68
This Southwest deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:35 am
STL
- ORD
1 stop8h 25m
Southwest
Deal found 2/3![Southwest logo]()
$69
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/238:22 pm
STL
- MDW
1 stop22h 45m
Frontier
Deal found 2/2![Frontier logo]()
$72
Find flight deals from Missouri to Indiana
Keep the following information in mind while searching for Missouri to Indiana flight deals. Data was last updated February 3, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $118 (Kiwi.com) |
One-way from | $40 (Southwest) |
Popular in | November |
Cheapest in | April |
Average price | $262 |
Good round-trip deal | $357 or less |
Good one-way deal | $239 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Missouri to Indiana that are best for you.
Fly from
Missouri
Fly to
Indiana
Route
Depart
Return
Price
Kansas CityIndianapolis
MCI - IND
MCIIND
Kansas City
Mon 2/23
10:55 am-6:31 pm
1 stop6h 36m
Indianapolis
Thu 2/26
7:27 pm-9:56 am
1 stop15h 29m
$151
St. LouisChicago
STL - MDW
STLMDW
Lambert-St Louis
Sat 5/2
6:55 pm-8:05 pm
Nonstop1h 10m
Chicago Midway
Tue 5/5
2:35 pm-8:00 pm
1 stop5h 25m
$154
Kansas CityCincinnati
MCI - CVG
MCICVG
Kansas City
Fri 2/27
11:00 am-5:32 pm
1 stop5h 32m
Cincinnati Cinci./N. Kentucky
Sun 3/1
1:07 pm-9:53 am
1 stop21h 46m
$160
ColumbiaChicago
COU - ORD
COUORD
Columbia Regional
Tue 3/3
3:10 pm-4:40 pm
Nonstop1h 30m
Chicago O'Hare Intl
Tue 3/10
9:00 am-10:33 am
Nonstop1h 33m
$179
ColumbiaChicago
COU - ORD
COUORD
Columbia Regional
Wed 2/25
11:15 am-12:45 pm
Nonstop1h 30m
Chicago O'Hare Intl
Sun 3/1
9:00 am-10:33 am
Nonstop1h 33m
$179
ColumbiaChicago
COU - ORD
COUORD
Columbia Regional
Sat 3/14
2:41 pm-4:09 pm
Nonstop1h 28m
Chicago O'Hare Intl
Tue 3/17
9:00 am-10:33 am
Nonstop1h 33m
$179
ColumbiaChicago
COU - ORD
COUORD
Columbia Regional
Thu 4/2
3:23 pm-4:56 pm
Nonstop1h 33m
Chicago O'Hare Intl
Sun 4/5
1:16 pm-2:48 pm
Nonstop1h 32m
$179
SpringfieldChicago
SGF - ORD
SGFORD
Springfield-Branson
Sat 4/4
6:30 pm-8:18 pm
Nonstop1h 48m
Chicago O'Hare Intl
Tue 4/7
3:35 pm-5:24 pm
Nonstop1h 49m
$189
SpringfieldChicago
SGF - ORD
SGFORD
Springfield-Branson
Mon 5/4
8:00 pm-9:43 pm
Nonstop1h 43m
Chicago O'Hare Intl
Sat 5/16
8:45 am-10:36 am
Nonstop1h 51m
$189
SpringfieldChicago
SGF - ORD
SGFORD
Springfield-Branson
Thu 5/14
8:00 pm-9:43 pm
Nonstop1h 43m
Chicago O'Hare Intl
Sun 5/17
7:57 pm-9:57 pm
Nonstop2h 00m
$189
Showing 1-10 of 60 results
Best time to book a flight from Missouri to Indiana
Have a flexible travel schedule? Discover the best time to fly to Indiana from Missouri with our price prediction graph.
MCI-IND
STL-MDW
COU-ORD
MCI-CVG
SGF-ORD
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Indiana
USMO-USIN
MCI-IND
STL-MDW
COU-ORD
MCI-CVG
What is the cheapest month to book a flight from Missouri to Indiana?
Currently, September is the cheapest month in which you can book a flight from Missouri to Indiana (average of $170). Flying from Missouri to Indiana in January is currently the most expensive (average of $260). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to IN?
Find hourly flight availability from Missouri to Indiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 3, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Indiana as you normally would.
Reviews of airlines servicing Indiana
Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated February 3, 2026.
Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from Missouri to Indiana by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Overall
8.0
Crew
8.6
Comfort
8.0
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Boarding
8.1
Overall
8.0
Crew
8.6
Comfort
8.0
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Boarding
8.1
Overall
8.0
Crew
8.6
Comfort
8.0
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Boarding
8.1
Overall
8.0
Crew
8.6
Comfort
8.0
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Boarding
8.1
Overall
8.0
Crew
8.6
Comfort
8.0
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from Missouri to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes for Missouri to Indiana
See prices for flight routes from nearby airports that may be better suited for you.
Top 4 airlines flying from Missouri to Indiana
Discover the top 4 airlines that operate flights from Missouri to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$178 | Average$379 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$204 | Average$355 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$204 | Average$287 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$207 | Average$364 | FlexibilityNo cancel fee | On-time69% |