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$66+ Cheap flights from Missouri to Indiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/7. Fares are subject to change and may not be available on all flights or dates of travel.
STL — IND
Jan 22 — Jan 291
Thu 1/22
Thu 1/29
1 adult, Economy
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Cheap flight deals from Missouri to Indiana

Cheapest flights from Missouri to Indiana
Explore the most affordable flight options available from Missouri to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2025.

This United Airlines deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:05 amSTL - ORD
Nonstop1h 35mUnited Airlines
Thu 1/112:56 pmORD - STL
Nonstop1h 30mUnited Airlines
Deal found 12/20$215
This American Airlines deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:12 amMCI - ORD
Nonstop1h 47mAmerican Airlines
Mon 1/268:12 amORD - MCI
1 stop8h 02mAmerican Airlines
Deal found 12/22$228
This American Airlines deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:12 amMCI - ORD
Nonstop1h 47mAmerican Airlines
Thu 1/14:05 pmORD - MCI
1 stop7h 48mAmerican Airlines
Deal found 12/22$237
This Delta deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3110:41 amMCI - MDW
1 stop6h 45mDelta
Mon 1/267:16 pmMDW - MCI
1 stop4h 11mDelta
Deal found 12/22$238
This United Airlines deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/286:34 pmCOU - ORD
Nonstop1h 36mUnited Airlines
Sun 1/41:00 pmORD - COU
Nonstop1h 35mUnited Airlines
Deal found 12/20$239
This Trip.com deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3111:33 amMCI - MDW
1 stop10h 39mFrontier
Sun 1/410:50 pmMDW - MCI
1 stop21h 00mFrontier
Deal found 12/22$242
This Delta deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3110:42 amMCI - ORD
1 stop4h 39mDelta
Mon 1/261:58 pmORD - MCI
2 stops9h 53mDelta
Deal found 12/22$243
This American Airlines deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/297:03 amSGF - ORD
Nonstop1h 47mAmerican Airlines
Mon 1/58:31 pmORD - SGF
Nonstop1h 57mAmerican Airlines
Deal found 12/22$249
This American Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/317:05 amSTL - ORD
1 stop7h 07mAmerican Airlines
Thu 1/17:07 amORD - STL
Nonstop1h 28mAmerican Airlines
Deal found 12/21$255
This American Airlines deal was found by Cheapflights users on 12/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2410:27 amSGF - ORD
Nonstop1h 42mAmerican Airlines
Wed 12/318:00 amORD - SGF
Nonstop1h 57mAmerican Airlines
Deal found 12/23$257
This American Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/257:30 amCOU - ORD
Nonstop1h 35mAmerican Airlines
Sun 12/285:47 pmORD - COU
Nonstop1h 25mAmerican Airlines
Deal found 12/21$264
This Southwest deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3112:10 pmMCI - MDW
1 stop4h 40mSouthwest
Thu 1/14:40 pmMDW - MCI
Nonstop1h 30mSouthwest
Deal found 12/22$267

Find flight deals from Missouri to Indiana

Keep the following information in mind while searching for Missouri to Indiana flight deals. Data was last updated December 23, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$141
(Kiwi.com)

One-way from

$66
(Mytrip)

Popular in

November

Cheapest in

April

Average price

$276

Good round-trip deal

$451 or less

Good one-way deal

$224 or less
Provider with most accurate pricing for Lambert-St Louis-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Indianapolis flights.
Search Deals
From Missouri to Indiana
Search Deals
One-way flight from Missouri to Indiana
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($49 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($29 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals
Price to beat on a round-trip flight from Missouri to Indiana.
Search Deals
Price to beat on a one-way flight from Missouri to Indiana.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 23, 2025.
Use the filters below to find and compare flights from Missouri to Indiana that are best for you.

Fly from

Missouri

Fly to

Indiana

Route

Depart

Return

Price

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Sat 1/31

12:12 pm-7:41 pm

1 stop7h 29m

Chicago O'Hare Intl

Mon 2/2

6:57 pm-6:51 am

2 stops35h 54m

$153

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Wed 2/4

6:40 pm-8:23 pm

Nonstop1h 43m

Chicago O'Hare Intl

Wed 2/11

1:00 pm-2:30 pm

Nonstop1h 30m

$153

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Wed 1/14

6:40 pm-8:23 pm

Nonstop1h 43m

Chicago O'Hare Intl

Wed 1/21

9:25 pm-10:58 pm

Nonstop1h 33m

$153

St. LouisChicago

STL - MDW

STLMDW

Lambert-St Louis

Sat 1/31

5:50 pm-7:00 pm

Nonstop1h 10m

Chicago Midway

Mon 2/2

6:10 am-7:35 am

Nonstop1h 25m

$157

Kansas CityIndianapolis

MCI - IND

MCIIND

Kansas City

Thu 2/19

8:28 pm-8:02 pm

1 stop22h 34m

Indianapolis

Wed 2/25

8:18 pm-10:30 am

1 stop15h 12m

$161

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Mon 1/12

1:07 pm-9:32 pm

1 stop8h 25m

Chicago O'Hare Intl

Thu 1/15

8:51 pm-7:54 am

1 stop11h 03m

$162

Kansas CityCincinnati

MCI - CVG

MCICVG

Kansas City

Sun 1/25

8:41 pm-8:53 pm

1 stop23h 12m

Cincinnati Cinci./N. Kentucky

Sat 1/31

3:23 pm-10:31 am

1 stop20h 08m

$167

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Mon 1/12

5:11 pm-1:13 pm

1 stop20h 02m

Chicago O'Hare Intl

Thu 1/15

3:22 pm-7:54 am

2 stops16h 32m

$169

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Wed 2/4

8:22 pm-1:37 pm

1 stop17h 15m

Chicago O'Hare Intl

Wed 2/11

5:32 pm-11:59 pm

2 stops30h 27m

$170

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Thu 1/22

11:20 am-12:55 pm

Nonstop1h 35m

Chicago O'Hare Intl

Sat 1/24

10:52 am-12:29 pm

Nonstop1h 37m

$171

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/21

Showing 1-10 of 60 results
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Best time to book a flight from Missouri to Indiana

Have a flexible travel schedule? Discover the best time to fly to Indiana from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Indiana

What is the cheapest month to book a flight from Missouri to Indiana?

Currently, August is the cheapest month in which you can book a flight from Missouri to Indiana (average of $161). Flying from Missouri to Indiana in June is currently the most expensive (average of $244). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to IN?

Find hourly flight availability from Missouri to Indiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 23, 2025.

A simple way to save on the total cost of your ticket is to fly from Missouri to Indiana in the evening. If you’re flexible enough to do this you can expect to save up to 50% on your trip compared to booking a flight in the morning.

Reviews of airlines servicing Indiana

Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated December 23, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from Missouri to Indiana by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,253 reviews

Boarding

8.1

Food

7.0

Comfort

8.0

Entertainment

7.5

Overall

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,253 reviews
Southwest
8.0
Very good
4,253 reviews

Boarding

8.1

Food

7.0

Comfort

8.0

Entertainment

7.5

Overall

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,014 reviews
Southwest
8.0
Very good
4,253 reviews

Boarding

8.1

Food

7.0

Comfort

8.0

Entertainment

7.5

Overall

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
United Airlines
7.4
Good
9,105 reviews
Southwest
8.0
Very good
4,253 reviews

Boarding

8.1

Food

7.0

Comfort

8.0

Entertainment

7.5

Overall

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,054 reviews
Southwest
8.0
Very good
4,253 reviews

Boarding

8.1

Food

7.0

Comfort

8.0

Entertainment

7.5

Overall

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Missouri to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Indiana?

    There are many flights that can get you from Missouri to Indiana in 1h 10m. Fly via United Airlines, Southwest, or Frontier to get the fastest option. There are 251 mi between Missouri and Indiana. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Missouri to Indiana one-way?

    One-way options have recently been found by users for as low as $448 on Delta. Other airlines that offer cheap prices include American Airlines from $470 and United Airlines from $562 one-way.

  • Can I find deals for flights from Missouri to Indiana that include hotel bookings?

    Yes. In addition to deals on Missouri to Indiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Indiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Indiana.

  • Can I find deals for business class flights from Missouri to Indiana?

    Yes. Cheapflights offers flight deals from Missouri to Indiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Indiana?

    Currently, August is the cheapest month in which you can book a flight from Missouri to Indiana (average of $161). Flying from Missouri to Indiana in June is currently the most expensive (average of $244). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Missouri to Indiana

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Missouri to Indiana

Discover the top 4 airlines that operate flights from Missouri to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$178Average$379FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$198Average$350FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$204Average$345FlexibilityNo cancel feeOn-time63%
DeltaCheapest$204Average$267FlexibilityNo cancel feeOn-timeN/A

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