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$55+ Cheap flights from Mississippi to Indiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/8. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — IND
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Find flight deals from Mississippi to Indiana

Cheapest flights from Mississippi to Indiana
Explore the most affordable flight options available from Mississippi to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This Mytrip deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/138:10 pmMEM - IND
1 stop22h 34mFrontier
Sun 11/168:39 pmIND - MEM
1 stop23h 43mFrontier
Deal found 10/29$178
This Booking.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/68:10 pmMEM - IND
1 stop22h 34mFrontier
Sun 11/98:39 pmIND - MEM
1 stop23h 43mFrontier
Deal found 10/29$214
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/135:10 amMOB - ORD
2 stops7h 58mAmerican Airlines
Sat 1/1010:10 amORD - MOB
1 stop6h 49mAmerican Airlines
Deal found 10/28$216
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/269:19 pmMEM - ORD
1 stop20h 11mMultiple Airlines
Wed 12/33:43 pmORD - MEM
1 stop24h 53mMultiple Airlines
Deal found 10/29$217
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/171:21 pmMEM - ORD
2 stops18h 07mMultiple Airlines
Wed 11/193:26 pmORD - MEM
1 stop18h 34mMultiple Airlines
Deal found 10/29$218
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/210:07 amMEM - ORD
1 stop12h 59mSpirit Airlines
Fri 12/512:09 pmORD - MEM
1 stop6h 38mSpirit Airlines
Deal found 10/30$220
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/229:17 pmMEM - ORD
1 stop17h 00mMultiple Airlines
Mon 1/126:05 amORD - MEM
1 stop9h 09mMultiple Airlines
Deal found 10/30$221
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2710:58 amMEM - IND
1 stop20h 10mMultiple Airlines
Thu 12/47:19 pmIND - MEM
2 stops20h 07mMultiple Airlines
Deal found 10/30$221
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/229:17 pmMEM - ORD
1 stop17h 00mMultiple Airlines
Thu 1/1510:00 pmORD - MEM
1 stop14h 31mMultiple Airlines
Deal found 10/30$223
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/238:47 pmMEM - ORD
2 stops25h 37mMultiple Airlines
Tue 1/136:05 amORD - MEM
1 stop9h 09mMultiple Airlines
Deal found 10/30$225
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/238:47 pmMEM - ORD
1 stop15h 52mMultiple Airlines
Fri 1/97:00 amORD - MEM
1 stop8h 14mMultiple Airlines
Deal found 10/30$227
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/238:47 pmMEM - ORD
1 stop15h 52mMultiple Airlines
Sat 1/108:15 amORD - MEM
1 stop6h 59mMultiple Airlines
Deal found 10/30$228

Cheap flight deals from Mississippi to Indiana

Keep the following information in mind while searching for Mississippi to Indiana flight deals. Data was last updated October 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$178
(Mytrip)

One-way from

$55
(Priceline)

Popular in

February

Cheapest in

January

Average price

$343
Provider with most accurate pricing for Jackson-Evers Intl-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Jackson-Evers Intl-Indianapolis flights.
Search Deals
From Mississippi to Indiana
Search Deals
One-way flight from Mississippi to Indiana
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($22 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Mississippi to Indiana that are best for you.

Fly from

Mississippi

Fly to

Indiana

Route

Depart

Return

Price

MemphisIndianapolis

MEM - IND

MEMIND

Memphis

Thu 11/13

8:10 pm-7:44 pm

1 stop22h 34m

Indianapolis

Sun 11/16

8:39 pm-7:22 pm

1 stop23h 43m

$178

MobileChicago

MOB - ORD

MOBORD

Mobile

Wed 4/15

7:15 pm-11:55 pm

1 stop4h 40m

Chicago O'Hare Intl

Sat 4/18

7:10 am-11:29 am

1 stop4h 19m

$211

MemphisIndianapolis

MEM - IND

MEMIND

Memphis

Thu 11/6

8:10 pm-7:44 pm

1 stop22h 34m

Indianapolis

Sun 11/9

8:39 pm-7:22 pm

1 stop23h 43m

$214

MemphisChicago

MEM - ORD

MEMORD

Memphis

Thu 12/4

8:07 pm-10:24 pm

2 stops26h 17m

Chicago O'Hare Intl

Sat 12/6

12:09 pm-6:47 pm

1 stop6h 38m

$221

MemphisIndianapolis

MEM - IND

MEMIND

Memphis

Thu 11/27

10:58 am-8:08 am

1 stop20h 10m

Indianapolis

Thu 12/4

7:19 pm-2:26 pm

2 stops20h 07m

$221

MobileChicago

MOB - ORD

MOBORD

Mobile

Tue 11/25

7:12 pm-12:02 am

1 stop4h 50m

Chicago O'Hare Intl

Tue 12/2

1:20 pm-6:32 pm

1 stop5h 12m

$230

GulfportChicago

GPT - ORD

GPTORD

Gulfport Biloxi Regional

Tue 11/25

5:55 pm-9:47 am

1 stop15h 52m

Chicago O'Hare Intl

Wed 11/26

6:15 pm-7:15 pm

1 stop25h 00m

$230

MemphisChicago

MEM - ORD

MEMORD

Memphis

Mon 12/8

7:39 am-9:35 am

Nonstop1h 56m

Chicago O'Hare Intl

Thu 12/11

12:45 pm-2:43 pm

Nonstop1h 58m

$231

MemphisChicago

MEM - MDW

MEMMDW

Memphis

Thu 12/4

7:30 am-9:05 am

Nonstop1h 35m

Chicago Midway

Mon 12/8

8:10 am-9:55 am

Nonstop1h 45m

$231

MemphisChicago

MEM - ORD

MEMORD

Memphis

Thu 12/4

7:39 am-9:35 am

Nonstop1h 56m

Chicago O'Hare Intl

Sat 12/6

8:00 pm-9:59 pm

Nonstop1h 59m

$238

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/30

Showing 1-10 of 60 results
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Best time to book a flight from Mississippi to Indiana

Have a flexible travel schedule? Discover the best time to fly to Indiana from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Indiana

What is the cheapest month to book a flight from Mississippi to Indiana?

Currently, March is the cheapest month in which you can book a flight from Mississippi to Indiana (average of $144). Flying from Mississippi to Indiana in June is currently the most expensive (average of $323). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to IN?

Find hourly flight availability from Mississippi to Indiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

One of the essential ways to save on airfare from Mississippi to Indiana is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the morning could potentially save you up to 15% on airfare.

How much does it cost to fly round-trip from Mississippi to Indiana?

Reviews of airlines servicing Indiana

Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated October 30, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and American Airlines from Mississippi to Indiana by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,243 reviews

Comfort

8.0

Boarding

8.1

Food

7.0

Overall

8.0

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,243 reviews
Southwest
8.0
Very good
4,243 reviews

Comfort

8.0

Boarding

8.1

Food

7.0

Overall

8.0

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
7,998 reviews
Southwest
8.0
Very good
4,243 reviews

Comfort

8.0

Boarding

8.1

Food

7.0

Overall

8.0

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,035 reviews
Southwest
8.0
Very good
4,243 reviews

Comfort

8.0

Boarding

8.1

Food

7.0

Overall

8.0

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mississippi to Indiana?

    There are many flights that can get you from Mississippi to Indiana in 1h 56m. Fly via Frontier, Delta, or United Airlines to get the fastest option. There are 492 mi between Mississippi and Indiana. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Mississippi to Indiana one-way?

    The cheapest airlines for a one-way flight from Mississippi to Indiana are United Airlines ($116), Southwest ($116), and Frontier ($126).

  • Can I find deals for flights from Mississippi to Indiana that include hotel bookings?

    Yes. In addition to deals on Mississippi to Indiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Indiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Indiana.

  • Can I find deals for business class flights from Mississippi to Indiana?

    Yes. Cheapflights offers flight deals from Mississippi to Indiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Indiana?

    Currently, March is the cheapest month in which you can book a flight from Mississippi to Indiana (average of $144). Flying from Mississippi to Indiana in June is currently the most expensive (average of $323). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Mississippi to Indiana

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Mississippi to Indiana

Discover the top 3 airlines that operate flights from Mississippi to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$236Average$400FlexibilityNo cancel feeOn-time71%
DeltaCheapest$239Average$425FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$316Average$381FlexibilityNo cancel feeOn-time63%

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