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$49+ Cheap flights from Mississippi to Indiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/17. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — IND
Mar 16 — Mar 231
Mon 3/16
Mon 3/23
1 adult, Economy
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Cheap flight deals from Mississippi to Indiana

Cheapest flights from Mississippi to Indiana
Explore the most affordable flight options available from Mississippi to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 14, 2026.

This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/117:30 am
MEM
-
ORD
Nonstop1h 56m
United Airlines
Wed 3/187:59 pm
ORD
-
MEM
Nonstop2h 00m
United Airlines
Deal found 2/10$97
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/15:05 am
MEM
-
MDW
Nonstop1h 35m
Southwest
Wed 4/18:40 pm
MDW
-
MEM
Nonstop1h 45m
Southwest
Deal found 2/10$97
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/113:25 pm
MEM
-
MDW
Nonstop1h 35m
Southwest
Wed 3/185:30 pm
MDW
-
MEM
1 stop4h 50m
Southwest
Deal found 2/10$107
This Southwest deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:35 am
MEM
-
ORD
1 stop8h 25m
Southwest
Wed 4/811:55 am
ORD
-
MEM
1 stop5h 35m
Southwest
Deal found 2/12$117
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/249:45 am
MEM
-
ORD
1 stop8h 50m
Southwest
Wed 3/252:40 pm
ORD
-
MEM
1 stop7h 40m
Southwest
Deal found 2/10$122
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/236:25 pm
MEM
-
ORD
Nonstop1h 59m
United Airlines
Wed 3/257:59 pm
ORD
-
MEM
Nonstop2h 00m
United Airlines
Deal found 2/10$134
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/53:00 pm
MEM
-
MDW
Nonstop1h 35m
Southwest
Thu 5/79:40 pm
MDW
-
MEM
Nonstop1h 45m
Southwest
Deal found 2/10$134
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/207:23 pm
MEM
-
ORD
Nonstop2h 01m
American Airlines
Wed 3/257:30 pm
ORD
-
MEM
Nonstop1h 56m
American Airlines
Deal found 2/10$144
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:10 am
MEM
-
ORD
1 stop7h 45m
Southwest
Sat 4/44:15 pm
ORD
-
MEM
1 stop5h 05m
Southwest
Deal found 2/10$154
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/134:25 pm
MEM
-
MDW
Nonstop1h 35m
Southwest
Tue 3/179:20 am
MDW
-
MEM
1 stop6h 00m
Southwest
Deal found 2/10$154
This United Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/47:30 am
MEM
-
ORD
Nonstop1h 55m
United Airlines
Tue 3/107:59 pm
ORD
-
MEM
Nonstop2h 00m
United Airlines
Deal found 2/11$157
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/46:15 am
MEM
-
MDW
1 stop6h 31m
Delta
Wed 3/111:10 pm
MDW
-
MEM
1 stop3h 47m
Delta
Deal found 2/11$157

Find flight deals from Mississippi to Indiana

Keep the following information in mind while searching for Mississippi to Indiana flight deals. Data was last updated February 14, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$97
(United Airlines)

One-way from

$49
(United Airlines)

Popular in

February

Cheapest in

December

Average price

$716
Provider with most accurate pricing for Jackson-Evers Intl-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Jackson-Evers Intl-Indianapolis flights.
Search Deals
From Mississippi to Indiana
Search Deals
One-way flight from Mississippi to Indiana
Search Deals
Highest demand for flights based on searches. 19% potential increase in price ($100 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($30 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 14, 2026.
Use the filters below to find and compare flights from Mississippi to Indiana that are best for you.

Fly from

Mississippi

Fly to

Indiana

Route

Depart

Return

Price

MemphisChicago

MEM - ORD

MEMORD

Memphis

Tue 3/24

6:25 pm-8:24 pm

Nonstop1h 59m

Chicago O'Hare Intl

Wed 3/25

7:59 pm-9:59 pm

Nonstop2h 00m

$97

MemphisChicago

MEM - MDW

MEMMDW

Memphis

Wed 4/1

5:05 am-6:40 am

Nonstop1h 35m

Chicago Midway

Wed 4/1

8:40 pm-10:25 pm

Nonstop1h 45m

$97

MemphisChicago

MEM - MDW

MEMMDW

Memphis

Wed 3/11

3:25 pm-5:00 pm

Nonstop1h 35m

Chicago Midway

Wed 3/18

5:30 pm-10:20 pm

1 stop4h 50m

$107

MemphisChicago

MEM - ORD

MEMORD

Memphis

Tue 3/31

9:45 am-6:35 pm

1 stop8h 50m

Chicago O'Hare Intl

Wed 4/1

2:40 pm-10:20 pm

1 stop7h 40m

$122

MemphisChicago

MEM - ORD

MEMORD

Memphis

Tue 4/7

9:45 am-6:25 pm

1 stop8h 40m

Chicago O'Hare Intl

Wed 4/8

11:55 am-9:45 pm

2 stops9h 50m

$122

MemphisChicago

MEM - ORD

MEMORD

Memphis

Tue 3/24

9:45 am-6:35 pm

1 stop8h 50m

Chicago O'Hare Intl

Wed 3/25

2:40 pm-10:20 pm

1 stop7h 40m

$122

MemphisChicago

MEM - ORD

MEMORD

Memphis

Mon 3/23

6:25 pm-8:24 pm

Nonstop1h 59m

Chicago O'Hare Intl

Wed 3/25

7:59 pm-9:59 pm

Nonstop2h 00m

$134

MemphisChicago

MEM - ORD

MEMORD

Memphis

Wed 4/1

7:30 am-9:26 am

Nonstop1h 56m

Chicago O'Hare Intl

Thu 4/30

8:50 am-10:54 am

Nonstop2h 04m

$134

MemphisChicago

MEM - ORD

MEMORD

Memphis

Tue 4/7

6:32 pm-8:35 pm

Nonstop2h 03m

Chicago O'Hare Intl

Thu 4/9

8:50 am-10:54 am

Nonstop2h 04m

$134

MemphisChicago

MEM - MDW

MEMMDW

Memphis

Tue 5/5

3:00 pm-4:35 pm

Nonstop1h 35m

Chicago Midway

Thu 5/7

9:40 pm-11:25 pm

Nonstop1h 45m

$134

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/12

Showing 1-10 of 60 results
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Best time to book a flight from Mississippi to Indiana

Have a flexible travel schedule? Discover the best time to fly to Indiana from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Indiana

What is the cheapest month to book a flight from Mississippi to Indiana?

Currently, March is the cheapest month in which you can book a flight from Mississippi to Indiana (average of $158). Flying from Mississippi to Indiana in February is currently the most expensive (average of $336). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Indiana

Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated February 14, 2026.
Get a feel of what it's like to fly with Delta and American Airlines from Mississippi to Indiana by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,203 reviews

Overall

7.9

Food

7.2

Crew

8.5

Comfort

7.9

Entertainment

7.8

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,203 reviews
Delta
7.9
Good
8,203 reviews

Overall

7.9

Food

7.2

Crew

8.5

Comfort

7.9

Entertainment

7.8

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,288 reviews
Delta
7.9
Good
8,203 reviews

Overall

7.9

Food

7.2

Crew

8.5

Comfort

7.9

Entertainment

7.8

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mississippi to Indiana?

    There are many flights that can get you from Mississippi to Indiana in 1h 35m. Fly via United Airlines, Southwest, or Frontier to get the fastest option. There are 481 mi between Mississippi and Indiana. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Mississippi to Indiana that include hotel bookings?

    Yes. In addition to deals on Mississippi to Indiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Indiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Indiana.

  • Can I find deals for business class flights from Mississippi to Indiana?

    Yes. Cheapflights offers flight deals from Mississippi to Indiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Indiana?

    Currently, March is the cheapest month in which you can book a flight from Mississippi to Indiana (average of $158). Flying from Mississippi to Indiana in February is currently the most expensive (average of $336). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Mississippi to Indiana

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Mississippi to Indiana

Discover the top 2 airlines that operate flights from Mississippi to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 14, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$138Average$425FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$224Average$407FlexibilityNo cancel feeOn-time71%

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