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$55+ Cheap flights from Mississippi to Indiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/15. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — IND
Dec 13 — Dec 201
Sat 12/13
Sat 12/20
1 adult, Economy
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Find flight deals from Mississippi to Indiana

Cheapest flights from Mississippi to Indiana
Explore the most affordable flight options available from Mississippi to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 13, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/218:17 pmMEM - MDW
1 stop25h 41mMultiple Airlines
Mon 12/298:15 amMDW - MEM
2 stops34h 16mMultiple Airlines
Deal found 11/11$211
This Kiwi.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/208:17 pmMEM - MDW
1 stop24h 47mMultiple Airlines
Wed 12/313:10 pmMDW - MEM
1 stop28h 12mMultiple Airlines
Deal found 11/11$212
This Kiwi.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/57:42 pmMEM - ORD
1 stop18h 39mMultiple Airlines
Sun 12/72:36 pmORD - MEM
1 stop28h 11mMultiple Airlines
Deal found 11/11$214
This Southwest deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/107:30 amMEM - MDW
Nonstop1h 35mSouthwest
Sat 12/138:15 amMDW - MEM
Nonstop1h 45mSouthwest
Deal found 11/11$214
This Mytrip deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/107:42 pmMEM - ORD
2 stops20h 05mSpirit Airlines
Sat 12/1312:09 pmORD - MEM
1 stop6h 38mSpirit Airlines
Deal found 11/11$216
This Kiwi.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/218:17 pmMEM - MDW
1 stop25h 41mMultiple Airlines
Wed 12/318:15 amMDW - MEM
2 stops34h 16mMultiple Airlines
Deal found 11/11$216
This Delta deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/912:05 pmMEM - ORD
1 stop4h 52mDelta
Wed 12/106:45 amORD - MEM
1 stop6h 47mDelta
Deal found 11/11$217
This Delta deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/97:00 amMEM - MDW
1 stop4h 55mDelta
Wed 12/106:00 amMDW - MEM
1 stop5h 42mDelta
Deal found 11/11$217
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/107:42 pmMEM - ORD
2 stops17h 26mMultiple Airlines
Fri 12/122:26 pmORD - MEM
1 stop28h 21mMultiple Airlines
Deal found 11/12$218
This Kiwi.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/47:42 pmMEM - MDW
1 stop26h 57mMultiple Airlines
Mon 12/88:42 pmMDW - MEM
2 stops15h 50mMultiple Airlines
Deal found 11/11$218
This United Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/86:24 pmMEM - ORD
Nonstop2h 01mUnited Airlines
Wed 12/1012:45 pmORD - MEM
Nonstop1h 58mUnited Airlines
Deal found 11/11$219
This Southwest deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/83:00 pmMEM - MDW
Nonstop1h 35mSouthwest
Wed 12/108:10 amMDW - MEM
Nonstop1h 45mSouthwest
Deal found 11/11$219

Cheap flight deals from Mississippi to Indiana

Keep the following information in mind while searching for Mississippi to Indiana flight deals. Data was last updated November 13, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$211
(American Airlines)

One-way from

$55
(Priceline)

Popular in

February

Cheapest in

October

Average price

$367
Provider with most accurate pricing for Jackson-Evers Intl-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Jackson-Evers Intl-Indianapolis flights.
Search Deals
From Mississippi to Indiana
Search Deals
One-way flight from Mississippi to Indiana
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($31 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from Mississippi to Indiana that are best for you.

Fly from

Mississippi

Fly to

Indiana

Route

Depart

Return

Price

MobileChicago

MOB - ORD

MOBORD

Mobile

Sat 1/31

6:33 am-1:22 pm

1 stop6h 49m

Chicago O'Hare Intl

Sat 2/7

10:10 am-4:59 pm

1 stop6h 49m

$211

MemphisChicago

MEM - MDW

MEMMDW

Memphis

Mon 12/22

8:17 pm-9:58 pm

1 stop25h 41m

Chicago Midway

Wed 12/31

8:15 am-6:31 pm

2 stops34h 16m

$216

MemphisChicago

MEM - ORD

MEMORD

Memphis

Tue 3/10

12:02 pm-4:48 pm

1 stop4h 46m

Chicago O'Hare Intl

Wed 3/11

7:10 am-2:26 pm

1 stop7h 16m

$217

MemphisChicago

MEM - MDW

MEMMDW

Memphis

Mon 12/8

7:30 am-9:05 am

Nonstop1h 35m

Chicago Midway

Wed 12/10

9:40 am-5:15 pm

1 stop7h 35m

$229

MemphisFort Wayne

MEM - FWA

MEMFWA

Memphis

Wed 2/18

6:15 am-1:36 pm

1 stop6h 21m

Fort Wayne

Sat 2/21

8:12 am-11:27 am

1 stop4h 15m

$229

MemphisIndianapolis

MEM - IND

MEMIND

Memphis

Wed 1/14

11:51 am-5:43 pm

1 stop4h 52m

Indianapolis

Sat 1/17

3:29 pm-10:51 pm

1 stop8h 22m

$230

MobileChicago

MOB - ORD

MOBORD

Mobile

Mon 11/24

1:23 pm-6:52 pm

1 stop5h 29m

Chicago O'Hare Intl

Tue 12/2

1:20 pm-6:32 pm

1 stop5h 12m

$230

MemphisChicago

MEM - ORD

MEMORD

Memphis

Sat 12/13

7:39 am-9:35 am

Nonstop1h 56m

Chicago O'Hare Intl

Sat 12/13

8:00 pm-9:59 pm

Nonstop1h 59m

$231

MemphisChicago

MEM - ORD

MEMORD

Memphis

Wed 12/31

7:30 am-9:33 am

Nonstop2h 03m

Chicago O'Hare Intl

Thu 1/1

12:45 pm-2:48 pm

Nonstop2h 03m

$231

MemphisChicago

MEM - ORD

MEMORD

Memphis

Sat 12/6

12:48 pm-4:48 pm

1 stop4h 00m

Chicago O'Hare Intl

Tue 12/9

4:20 pm-8:52 pm

1 stop4h 32m

$234

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/11

Showing 1-10 of 60 results
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Best time to book a flight from Mississippi to Indiana

Have a flexible travel schedule? Discover the best time to fly to Indiana from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Indiana

What is the cheapest month to book a flight from Mississippi to Indiana?

Currently, March is the cheapest month in which you can book a flight from Mississippi to Indiana (average of $143). Flying from Mississippi to Indiana in June is currently the most expensive (average of $323). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to IN?

Find hourly flight availability from Mississippi to Indiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 13, 2025.

One of the essential ways to save on airfare from Mississippi to Indiana is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the morning could potentially save you up to 15% on airfare.

Reviews of airlines servicing Indiana

Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated November 13, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and American Airlines from Mississippi to Indiana by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Overall

8.0

Crew

8.6

Boarding

8.1

Food

7.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,242 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Overall

8.0

Crew

8.6

Boarding

8.1

Food

7.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
8,007 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Overall

8.0

Crew

8.6

Boarding

8.1

Food

7.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,051 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Overall

8.0

Crew

8.6

Boarding

8.1

Food

7.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mississippi to Indiana?

    There are many flights that can get you from Mississippi to Indiana in 1h 35m. Fly via American Airlines, Delta, or Southwest to get the fastest option. There are 481 mi between Mississippi and Indiana. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Mississippi to Indiana one-way?

    The cheapest airlines for a one-way flight from Mississippi to Indiana are Frontier ($78), United Airlines ($99), and Southwest ($99).

  • Can I find deals for flights from Mississippi to Indiana that include hotel bookings?

    Yes. In addition to deals on Mississippi to Indiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Indiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Indiana.

  • Can I find deals for business class flights from Mississippi to Indiana?

    Yes. Cheapflights offers flight deals from Mississippi to Indiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Indiana?

    Currently, March is the cheapest month in which you can book a flight from Mississippi to Indiana (average of $143). Flying from Mississippi to Indiana in June is currently the most expensive (average of $323). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Mississippi to Indiana

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Mississippi to Indiana

Discover the top 3 airlines that operate flights from Mississippi to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$183Average$422FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$236Average$404FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$316Average$381FlexibilityNo cancel feeOn-time63%

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