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$75+ Cheap flights from Mississippi to Indiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/22. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — IND
Aug 27 — Sep 31
Wed 8/27
Wed 9/3
1 adult, Economy
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Cheap flight deals from Mississippi to Indiana

Keep the following information in mind while searching for Mississippi to Indiana flight deals. Data was last updated August 22, 2025.

Round-trip from

$187
(FlightHub)

One-way from

$88
(FlightHub)

Popular in

February

Cheapest in

January

Average price

$601
From Mississippi to Indiana
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One-way flight from Mississippi to Indiana
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Highest demand for flights based on searches. 6% potential increase in price ($28 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($19 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Mississippi to Indiana

Cheapest flights from Mississippi to Indiana
Explore the most affordable flight options available from Mississippi to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 22, 2025.

This FlightHub deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/187:00 amMEM - ORD
1 stop11h 50mSpirit Airlines
Sat 9/205:17 pmORD - MEM
1 stop6h 33mSpirit Airlines
Deal found 8/21$187
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/177:30 amMEM - ORD
Nonstop2h 01mUnited Airlines
Wed 9/247:45 pmORD - MEM
Nonstop1h 58mUnited Airlines
Deal found 8/20$197
This Southwest deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/107:30 amMEM - MDW
Nonstop1h 35mSouthwest
Wed 12/178:15 amMDW - MEM
Nonstop1h 45mSouthwest
Deal found 8/19$197
This United Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/302:05 pmBTR - ORD
1 stop7h 35mUnited Airlines
Fri 9/57:00 amORD - BTR
1 stop6h 19mUnited Airlines
Deal found 8/21$199
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/65:27 pmMEM - ORD
Nonstop2h 05mAmerican Airlines
Wed 10/88:02 amORD - MEM
Nonstop1h 47mAmerican Airlines
Deal found 8/21$199
This Southwest deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/231:50 pmMEM - MDW
Nonstop1h 40mSouthwest
Thu 9/258:45 pmMDW - MEM
Nonstop1h 40mSouthwest
Deal found 8/21$199
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/187:30 amMEM - ORD
Nonstop2h 01mUnited Airlines
Sat 9/208:58 amORD - MEM
Nonstop2h 00mUnited Airlines
Deal found 8/20$201
This Southwest deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/186:10 pmMEM - MDW
Nonstop1h 35mSouthwest
Sat 9/208:30 amMDW - MEM
Nonstop1h 40mSouthwest
Deal found 8/20$201
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/237:00 amMEM - ORD
Nonstop1h 58mAmerican Airlines
Thu 9/2510:13 pmORD - MEM
Nonstop1h 46mAmerican Airlines
Deal found 8/21$203
This Southwest deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/306:35 amMEM - MDW
1 stop7h 15mSouthwest
Sun 8/319:15 amMDW - MEM
Nonstop1h 35mSouthwest
Deal found 8/20$207
This FlightHub deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/148:04 pmMEM - ORD
1 stop13h 33mMultiple Airlines
Tue 9/165:17 pmORD - MEM
1 stop6h 33mMultiple Airlines
Deal found 8/21$208
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/35:55 pmMOB - ORD
1 stop6h 04mAmerican Airlines
Wed 10/18:38 amORD - MOB
1 stop7h 55mAmerican Airlines
Deal found 8/21$211

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 22, 2025.
Use the filters below to find and compare flights from Mississippi to Indiana that are best for you.

Fly from

Mississippi

Fly to

Indiana

Route

Depart

Return

Price

MemphisChicago

MEM - ORD

MEMORD

Memphis

Thu 9/18

7:00 am-6:50 pm

1 stop11h 50m

Chicago O'Hare Intl

Sat 9/20

5:17 pm-11:50 pm

1 stop6h 33m

$187

MemphisChicago

MEM - ORD

MEMORD

Memphis

Tue 9/16

7:00 am-4:12 pm

1 stop9h 12m

Chicago O'Hare Intl

Thu 9/18

12:05 pm-7:30 pm

1 stop7h 25m

$193

MemphisChicago

MEM - ORD

MEMORD

Memphis

Tue 9/9

7:00 am-4:12 pm

1 stop9h 12m

Chicago O'Hare Intl

Tue 9/30

5:17 pm-11:50 pm

1 stop6h 33m

$193

MemphisChicago

MEM - ORD

MEMORD

Memphis

Tue 9/23

7:00 am-4:12 pm

1 stop9h 12m

Chicago O'Hare Intl

Wed 9/24

5:17 pm-11:50 pm

1 stop6h 33m

$193

MemphisChicago

MEM - ORD

MEMORD

Memphis

Wed 9/24

7:00 am-4:12 pm

1 stop9h 12m

Chicago O'Hare Intl

Mon 9/29

6:30 am-7:00 pm

1 stop12h 30m

$193

MemphisChicago

MEM - ORD

MEMORD

Memphis

Fri 10/24

7:00 am-6:53 pm

1 stop11h 53m

Chicago O'Hare Intl

Sun 10/26

6:00 am-3:12 pm

1 stop9h 12m

$193

MemphisChicago

MEM - ORD

MEMORD

Memphis

Tue 9/9

5:18 pm-7:26 pm

Nonstop2h 08m

Chicago O'Hare Intl

Tue 9/30

8:20 am-10:13 am

Nonstop1h 53m

$197

MemphisChicago

MEM - MDW

MEMMDW

Memphis

Wed 12/10

7:30 am-9:05 am

Nonstop1h 35m

Chicago Midway

Wed 12/17

8:15 am-10:00 am

Nonstop1h 45m

$197

MemphisChicago

MEM - ORD

MEMORD

Memphis

Thu 9/4

3:35 pm-5:43 pm

Nonstop2h 08m

Chicago O'Hare Intl

Fri 9/5

7:01 pm-8:59 pm

Nonstop1h 58m

$197

MemphisChicago

MEM - MDW

MEMMDW

Memphis

Tue 9/23

1:50 pm-3:30 pm

Nonstop1h 40m

Chicago Midway

Thu 9/25

8:45 pm-10:25 pm

Nonstop1h 40m

$199

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/19

Showing 1-10 of 60 results
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Best time to book a flight from Mississippi to Indiana

Have a flexible travel schedule? Discover the best time to fly to Indiana from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Indiana

What is the cheapest month to book a flight from Mississippi to Indiana?

Currently, August is the cheapest month in which you can book a flight from Mississippi to Indiana (average of $295). Flying from Mississippi to Indiana in March is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to IN?

Find hourly flight availability from Mississippi to Indiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 22, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mississippi to Indiana as you normally would.

How much does it cost to fly round-trip from Mississippi to Indiana?

Reviews of airlines servicing Indiana

Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated August 22, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and American Airlines from Mississippi to Indiana by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,245 reviews

Boarding

8.1

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,245 reviews
Southwest
8.0
Very good
4,245 reviews

Boarding

8.1

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,981 reviews
Southwest
8.0
Very good
4,245 reviews

Boarding

8.1

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,245 reviews

Boarding

8.1

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mississippi to Indiana?

    There are many flights that can get you from Mississippi to Indiana in 1h 35m. Fly via Spirit Airlines, Southwest, or American Airlines to get the fastest option. There are 481 mi between Mississippi and Indiana. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Mississippi to Indiana one-way?

    The cheapest airlines for a one-way flight from Mississippi to Indiana are Frontier ($75), Southwest ($99), and Delta ($106).

  • Can I find deals for flights from Mississippi to Indiana that include hotel bookings?

    Yes. In addition to deals on Mississippi to Indiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Indiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Indiana.

  • Can I find deals for business class flights from Mississippi to Indiana?

    Yes. Cheapflights offers flight deals from Mississippi to Indiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Indiana?

    Currently, August is the cheapest month in which you can book a flight from Mississippi to Indiana (average of $295). Flying from Mississippi to Indiana in March is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Mississippi to Indiana

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Mississippi to Indiana

Discover the top 3 airlines that operate flights from Mississippi to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$236Average$409FlexibilityNo cancel feeOn-time71%
DeltaCheapest$238Average$350FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$316Average$376FlexibilityNo cancel feeOn-time63%

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