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$49+ Cheap flights from Mississippi to Indiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/28. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — IND
Feb 27 — Mar 61
Fri 2/27
Fri 3/6
1 adult, Economy
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Cheap flight deals from Mississippi to Indiana

Cheapest flights from Mississippi to Indiana
Explore the most affordable flight options available from Mississippi to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 28, 2026.

This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/245:08 am
MEM
-
ORD
Nonstop2h 03m
American Airlines
Tue 3/39:05 am
ORD
-
MEM
Nonstop2h 00m
American Airlines
Deal found 1/27$97
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/243:05 pm
MEM
-
MDW
Nonstop1h 40m
Southwest
Tue 3/38:10 am
MDW
-
MEM
Nonstop1h 45m
Southwest
Deal found 1/27$97
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/117:40 am
MEM
-
ORD
1 stop5h 10m
Southwest
Wed 3/112:40 pm
ORD
-
MEM
1 stop7h 40m
Southwest
Deal found 1/27$122
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/177:23 pm
MEM
-
ORD
Nonstop2h 01m
American Airlines
Thu 2/199:05 am
ORD
-
MEM
Nonstop2h 00m
American Airlines
Deal found 1/28$134
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/255:05 am
MEM
-
MDW
Nonstop1h 35m
Southwest
Thu 3/269:35 pm
MDW
-
MEM
Nonstop1h 45m
Southwest
Deal found 1/27$134
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/147:30 am
MEM
-
ORD
Nonstop1h 56m
United Airlines
Tue 3/177:59 pm
ORD
-
MEM
Nonstop2h 00m
United Airlines
Deal found 1/27$144
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/173:30 pm
MEM
-
MDW
Nonstop1h 35m
Southwest
Thu 2/1912:20 pm
MDW
-
MEM
1 stop5h 20m
Southwest
Deal found 1/27$144
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/188:15 am
MEM
-
ORD
1 stop4h 45m
Southwest
Sat 2/211:00 pm
ORD
-
MEM
1 stop7h 35m
Southwest
Deal found 1/27$154
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/186:40 am
MEM
-
MDW
1 stop7h 05m
Southwest
Sat 2/211:30 pm
MDW
-
MEM
1 stop6h 15m
Southwest
Deal found 1/27$154
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/187:01 am
MEM
-
ORD
Nonstop2h 04m
American Airlines
Fri 2/2010:10 pm
ORD
-
MEM
Nonstop1h 53m
American Airlines
Deal found 1/27$157
This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/127:04 pm
MEM
-
ORD
2 stops28h 43m
Multiple Airlines
Wed 2/186:02 pm
ORD
-
MEM
1 stop24h 07m
Multiple Airlines
Deal found 1/25$161
This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/93:40 pm
MEM
-
ORD
1 stop24h 12m
Multiple Airlines
Wed 2/186:02 pm
ORD
-
MEM
1 stop24h 07m
Multiple Airlines
Deal found 1/25$169

Find flight deals from Mississippi to Indiana

Keep the following information in mind while searching for Mississippi to Indiana flight deals. Data was last updated January 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$97
(American Airlines)

One-way from

$49
(United Airlines)

Popular in

February

Cheapest in

January

Average price

$239
Provider with most accurate pricing for Jackson-Evers Intl-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Jackson-Evers Intl-Indianapolis flights.
Search Deals
From Mississippi to Indiana
Search Deals
One-way flight from Mississippi to Indiana
Search Deals
High demand for flights, 1% potential price rise
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
Use the filters below to find and compare flights from Mississippi to Indiana that are best for you.

Fly from

Mississippi

Fly to

Indiana

Route

Depart

Return

Price

MemphisChicago

MEM - ORD

MEMORD

Memphis

Wed 3/11

7:30 am-9:26 am

Nonstop1h 56m

Chicago O'Hare Intl

Wed 3/11

7:59 pm-9:59 pm

Nonstop2h 00m

$97

MemphisChicago

MEM - MDW

MEMMDW

Memphis

Tue 2/24

3:05 pm-4:45 pm

Nonstop1h 40m

Chicago Midway

Tue 3/3

12:15 pm-5:10 pm

1 stop4h 55m

$107

MemphisChicago

MEM - ORD

MEMORD

Memphis

Wed 3/11

7:40 am-12:50 pm

1 stop5h 10m

Chicago O'Hare Intl

Wed 3/11

2:40 pm-10:20 pm

1 stop7h 40m

$122

MemphisChicago

MEM - ORD

MEMORD

Memphis

Sat 3/14

7:30 am-9:26 am

Nonstop1h 56m

Chicago O'Hare Intl

Tue 3/17

7:59 pm-9:59 pm

Nonstop2h 00m

$144

MemphisChicago

MEM - MDW

MEMMDW

Memphis

Wed 3/25

6:45 pm-11:55 pm

1 stop5h 10m

Chicago Midway

Thu 3/26

9:35 pm-11:20 pm

Nonstop1h 45m

$144

MemphisChicago

MEM - ORD

MEMORD

Memphis

Wed 2/25

7:30 am-9:25 am

Nonstop1h 55m

Chicago O'Hare Intl

Wed 3/4

7:59 pm-9:59 pm

Nonstop2h 00m

$171

MemphisChicago

MEM - ORD

MEMORD

Memphis

Tue 2/24

7:30 am-9:25 am

Nonstop1h 55m

Chicago O'Hare Intl

Tue 3/3

7:59 pm-9:59 pm

Nonstop2h 00m

$171

MemphisChicago

MEM - MDW

MEMMDW

Memphis

Sat 2/28

5:40 pm-7:15 pm

Nonstop1h 35m

Chicago Midway

Mon 3/2

8:45 pm-10:30 pm

Nonstop1h 45m

$171

MemphisChicago

MEM - ORD

MEMORD

Memphis

Tue 4/21

6:29 am-12:45 pm

1 stop6h 16m

Chicago O'Hare Intl

Thu 4/23

5:10 am-9:35 am

1 stop4h 25m

$174

MemphisChicago

MEM - ORD

MEMORD

Memphis

Tue 2/17

6:15 am-1:20 pm

1 stop7h 05m

Chicago O'Hare Intl

Thu 2/19

5:25 am-10:52 am

1 stop5h 27m

$174

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 60 results
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Best time to book a flight from Mississippi to Indiana

Have a flexible travel schedule? Discover the best time to fly to Indiana from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Indiana

What is the cheapest month to book a flight from Mississippi to Indiana?

Currently, March is the cheapest month in which you can book a flight from Mississippi to Indiana (average of $143). Flying from Mississippi to Indiana in June is currently the most expensive (average of $323). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Indiana

Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated January 28, 2026.
Get a feel of what it's like to fly with Delta and American Airlines from Mississippi to Indiana by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,123 reviews

Boarding

8.1

Entertainment

7.8

Food

7.2

Overall

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,123 reviews
Delta
7.9
Good
8,123 reviews

Boarding

8.1

Entertainment

7.8

Food

7.2

Overall

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,201 reviews
Delta
7.9
Good
8,123 reviews

Boarding

8.1

Entertainment

7.8

Food

7.2

Overall

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mississippi to Indiana?

    There are many flights that can get you from Mississippi to Indiana in 1h 40m. Fly via United Airlines, Southwest, or American Airlines to get the fastest option. There are 481 mi between Mississippi and Indiana. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Mississippi to Indiana that include hotel bookings?

    Yes. In addition to deals on Mississippi to Indiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Indiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Indiana.

  • Can I find deals for business class flights from Mississippi to Indiana?

    Yes. Cheapflights offers flight deals from Mississippi to Indiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Indiana?

    Currently, March is the cheapest month in which you can book a flight from Mississippi to Indiana (average of $143). Flying from Mississippi to Indiana in June is currently the most expensive (average of $323). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Mississippi to Indiana

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Mississippi to Indiana

Discover the top 2 airlines that operate flights from Mississippi to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$163Average$432FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$236Average$404FlexibilityNo cancel feeOn-time71%

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