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$60+ Cheap flights from Knoxville (TYS) to Houston

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/5. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — HOU
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheapflights Tip: The best prices from Knoxville McGhee Tyson to Houston are usually found in August or July, booked 51 days in advance, depart on a Monday or Sunday and return on a Tuesday

Cheap flight deals from Knoxville to Houston

Cheapest flights from Knoxville to Houston
Explore the most affordable flight options available from Knoxville to Houston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/308:00 amTYS - IAH
1 stop26h 15mMultiple Airlines
Tue 1/68:13 pmIAH - TYS
2 stops44h 40mMultiple Airlines
Deal found 12/9$282
This Kiwi.com deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:33 pmTYS - IAH
2 stops18h 12mMultiple Airlines
Sun 1/49:34 pmIAH - TYS
1 stop11h 41mMultiple Airlines
Deal found 12/10$299
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/179:10 amTYS - IAH
Nonstop2h 42mUnited Airlines
Sat 12/204:35 pmIAH - TYS
Nonstop2h 15mUnited Airlines
Deal found 12/10$319
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/185:52 pmTYS - IAH
1 stop15h 12mMultiple Airlines
Fri 12/1912:50 pmIAH - TYS
1 stop26h 43mMultiple Airlines
Deal found 12/11$321
This Kiwi.com deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/219:08 amTYS - IAH
1 stop16h 46mMultiple Airlines
Mon 12/299:34 pmIAH - TYS
2 stops41h 41mMultiple Airlines
Deal found 12/9$348
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/254:29 pmTYS - IAH
1 stop4h 57mAmerican Airlines
Tue 12/306:02 pmIAH - TYS
1 stop4h 43mAmerican Airlines
Deal found 12/11$349
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/185:52 pmTYS - IAH
1 stop15h 12mMultiple Airlines
Sat 12/206:19 pmIAH - TYS
2 stops50h 34mMultiple Airlines
Deal found 12/11$354
This Kiwi.com deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/239:27 pmTYS - IAH
1 stop21h 23mMultiple Airlines
Sun 12/285:54 amIAH - TYS
2 stops27h 21mMultiple Airlines
Deal found 12/10$359
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/185:23 amTYS - HOU
1 stop7h 16mAmerican Airlines
Sat 12/206:07 pmHOU - TYS
1 stop4h 38mAmerican Airlines
Deal found 12/11$424
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/255:23 amTYS - HOU
1 stop5h 20mAmerican Airlines
Tue 12/305:40 amHOU - TYS
1 stop4h 48mAmerican Airlines
Deal found 12/10$429
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/165:24 amTYS - HOU
1 stop5h 14mAmerican Airlines
Fri 1/29:05 amHOU - TYS
1 stop5h 34mAmerican Airlines
Deal found 12/11$444
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/124:22 pmTYS - HOU
1 stop4h 56mAmerican Airlines
Mon 12/1512:16 pmHOU - TYS
1 stop4h 11mAmerican Airlines
Deal found 12/11$459

Find flight deals from Knoxville to Houston

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Houston (HO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 12, 2025.

Round-trip from

$128
(Frontier)

One-way from

$60
(Kiwi.com)

Popular in

March

Cheapest in

August

Average price

$279
From Knoxville McGhee Tyson to Houston
Search Deals
One-way flight from Knoxville McGhee Tyson to Houston
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($50 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Houston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Knoxville to Houston that are best for you.

Fly from

Knoxville

Fly to

Houston

Route

Depart

Return

Price

KnoxvilleHouston

TYS - IAH

TYSIAH

Knoxville McGhee Tyson

Fri 2/6

4:25 pm-12:33 am

1 stop9h 08m

Houston George Bush Intcntl

Mon 2/9

6:45 am-3:35 pm

1 stop7h 50m

$128

KnoxvilleHouston

TYS - HOU

TYSHOU

Knoxville McGhee Tyson

Fri 1/2

5:56 pm-7:20 pm

Nonstop2h 24m

Houston Hobby

Mon 1/5

8:20 pm-11:21 pm

Nonstop2h 01m

$162

KnoxvilleHouston

TYS - IAH

TYSIAH

Knoxville McGhee Tyson

Fri 1/30

6:59 am-8:50 am

Nonstop2h 51m

Houston George Bush Intcntl

Sat 1/31

8:29 pm-11:44 pm

Nonstop2h 15m

$209

KnoxvilleHouston

TYS - HOU

TYSHOU

Knoxville McGhee Tyson

Fri 2/6

6:51 pm-10:46 pm

1 stop4h 55m

Houston Hobby

Mon 2/9

6:00 am-11:34 am

1 stop4h 34m

$229

KnoxvilleHouston

TYS - HOU

TYSHOU

Knoxville McGhee Tyson

Fri 1/16

12:19 pm-6:06 pm

1 stop6h 47m

Houston Hobby

Wed 1/21

6:00 am-11:31 am

1 stop4h 31m

$229

KnoxvilleHouston

TYS - IAH

TYSIAH

Knoxville McGhee Tyson

Fri 1/16

4:41 pm-9:10 pm

1 stop5h 29m

Houston George Bush Intcntl

Mon 1/19

6:00 am-11:34 am

1 stop4h 34m

$229

KnoxvilleHouston

TYS - IAH

TYSIAH

Knoxville McGhee Tyson

Fri 1/30

5:14 pm-11:59 pm

1 stop7h 45m

Houston George Bush Intcntl

Sat 1/31

8:00 am-1:54 pm

1 stop4h 54m

$229

KnoxvilleHouston

TYS - HOU

TYSHOU

Knoxville McGhee Tyson

Sat 1/17

6:51 pm-10:46 pm

1 stop4h 55m

Houston Hobby

Mon 1/19

6:00 am-11:34 am

1 stop4h 34m

$249

KnoxvilleHouston

TYS - IAH

TYSIAH

Knoxville McGhee Tyson

Sat 1/17

4:06 pm-8:15 pm

1 stop5h 09m

Houston George Bush Intcntl

Mon 1/19

6:00 am-11:34 am

1 stop4h 34m

$249

KnoxvilleHouston

TYS - IAH

TYSIAH

Knoxville McGhee Tyson

Mon 3/9

7:05 am-8:50 am

Nonstop2h 45m

Houston George Bush Intcntl

Mon 3/16

4:40 pm-7:55 pm

Nonstop2h 15m

$264

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/11

Showing 1-10 of 40 results
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Best time to book a flight from Knoxville to Houston

Have a flexible travel schedule? Discover the best time to fly to Houston from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Houston

How far ahead should I book a flight from Knoxville to Houston?

Use this chart to determine the optimal time to book a round-trip flight from Knoxville to Houston. Price data was last updated on December 5, 2025.

The best time to book flights from Knoxville to Houston is 51 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Knoxville to Houston?

Currently, June is the cheapest month in which you can book a flight from Knoxville to Houston (average of $63). Flying from Knoxville to Houston in September is currently the most expensive (average of $196). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to HOU?

Find hourly flight availability from Knoxville to Houston. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 28% on flights from Knoxville to Houston by exploring options for tickets in the evening.

What is the cheapest day to fly from Knoxville to Houston?

Use this chart to determine the cheapest time to fly round-trip from Knoxville to Houston. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Knoxville to Houston flight should consider departing on Wednesday afternoons when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Houston

Get insights into the airlines that provide service to Houston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Houston. Reviews last updated December 12, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Knoxville to Houston have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,095 reviews
Delta
7.9
Good
8,007 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,050 reviews
Delta
7.9
Good
8,007 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Allegiant Air
7.2
Good
699 reviews
Delta
7.9
Good
8,007 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Houston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Houston?

    If you book a flight to Houston from Knoxville, you will be flying from McGhee Tyson, which is the city’s only airport. Knoxville McGhee Tyson (TYS) is located 11.3 mi from the center of Knoxville. There are 0 flights from McGhee Tyson to Houston per day from 4 different airlines.

  • How long is the flight from Knoxville to Houston?

    Departing from Knoxville to Houston will take you 2h 24m. The distance between Knoxville and Houston is about 781 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Knoxville to Houston round-trip?

    Allegiant Air, at $65, was found to be the cheapest airline from Knoxville to Houston.Alternate airlines to your destination round-trip include Delta and American Airlines. These flights start at 79% lower than the current average price 3 months from now.

  • What are the cheapest airlines to fly from Knoxville to Houston one-way?

    The cheapest airline one-way is Allegiant Air, with whom users have recently found tickets for as low as $51. However, be on the lookout for offers from Frontier and American Airlines, as they are both options that can get you from Knoxville to Houston for a low price.

  • What are the cheapest flights from Knoxville to Houston?

    The cheapest flight price from Knoxville to Houston is $52. On average you can expect to pay $125. The most popular route, (Knoxville McGhee Tyson - Houston Hobby), can usually be booked for $180.

  • Can I find deals for flights from Knoxville to Houston that include hotel bookings?

    Yes. In addition to deals on Knoxville to Houston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Houston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Houston.

  • Can I find deals for business class flights from Knoxville to Houston?

    Yes. Cheapflights offers flight deals from Knoxville to Houston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Houston?

    Currently, June is the cheapest month in which you can book a flight from Knoxville to Houston (average of $63). Flying from Knoxville to Houston in September is currently the most expensive (average of $196). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Knoxville to Houston

Discover the top 4 airlines that operate flights from Knoxville to Houston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$82Average$135FlexibilityNo cancel feeOn-time88%
DeltaCheapest$228Average$283FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$228Average$377FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$230Average$380FlexibilityNo cancel feeOn-time69%

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