$105+ Cheap flights from Knoxville (TYS) to Houston
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/9. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — HOU
Apr 19 — Apr 261
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Houston with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Knoxville McGhee Tyson to Houston are usually found in August or July, booked 81 days in advance, depart on a Monday or Sunday and return on a Tuesday
Cheap flight deals from Knoxville to Houston
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Cheapest flights from Knoxville to HoustonExplore the most affordable flight options available from Knoxville to Houston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 20, 2026.
Explore the most affordable flight options available from Knoxville to Houston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 20, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/85:30 pm
TYS
- HOU
Nonstop2h 11m
Allegiant Air
Fri 6/197:44 pm
HOU
- TYS
Nonstop2h 09m
Allegiant Air
Deal found 3/20![Allegiant Air logo]()
$129
This Cheapflightsfares deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/295:30 pm
TYS
- HOU
Nonstop2h 19m
Allegiant Air
Mon 6/17:39 pm
HOU
- TYS
Nonstop2h 03m
Allegiant Air
Deal found 3/19![Allegiant Air logo]()
$155
This Priceline deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/304:28 pm
TYS
- IAH
1 stop9h 20m
Frontier
Sun 5/36:45 am
IAH
- TYS
1 stop7h 48m
Frontier
Deal found 3/20![Frontier logo]()
$181
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/169:32 pm
TYS
- IAH
1 stop18h 14m
Multiple Airlines
Mon 4/207:48 pm
IAH
- TYS
1 stop12h 52m
Multiple Airlines
Deal found 3/17![Multiple Airlines logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/154:25 pm
TYS
- IAH
1 stop7h 22m
Multiple Airlines
Wed 4/226:05 am
IAH
- TYS
2 stops32h 36m
Multiple Airlines
Deal found 3/18![Multiple Airlines logo]()
$216
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/302:06 pm
TYS
- IAH
1 stop20h 39m
Multiple Airlines
Tue 3/319:15 pm
IAH
- TYS
1 stop14h 30m
Multiple Airlines
Deal found 3/19![Multiple Airlines logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/18:30 am
TYS
- IAH
1 stop15h 04m
Multiple Airlines
Sun 4/511:32 am
IAH
- TYS
1 stop11h 07m
Multiple Airlines
Deal found 3/15![Multiple Airlines logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:10 pm
TYS
- IAH
1 stop26h 03m
Multiple Airlines
Sun 4/1211:51 am
IAH
- TYS
1 stop9h 42m
Multiple Airlines
Deal found 3/16![Multiple Airlines logo]()
$233
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3011:27 am
TYS
- IAH
2 stops21h 32m
Multiple Airlines
Sun 5/39:46 am
IAH
- TYS
1 stop9h 49m
Multiple Airlines
Deal found 3/20![Multiple Airlines logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/303:29 pm
TYS
- IAH
1 stop19h 16m
Multiple Airlines
Wed 4/112:46 pm
IAH
- TYS
1 stop25h 25m
Multiple Airlines
Deal found 3/18![Multiple Airlines logo]()
$236
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:20 pm
TYS
- IAH
1 stop15h 18m
Multiple Airlines
Mon 4/207:48 pm
IAH
- TYS
1 stop12h 52m
Multiple Airlines
Deal found 3/16![Multiple Airlines logo]()
$238
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:10 pm
TYS
- IAH
1 stop26h 03m
Multiple Airlines
Mon 4/1311:15 am
IAH
- TYS
1 stop10h 09m
Multiple Airlines
Deal found 3/16![Multiple Airlines logo]()
$251
Best flights from Knoxville to HoustonDiscover carefully curated flight deals from Knoxville to Houston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 20, 2026.
Discover carefully curated flight deals from Knoxville to Houston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 20, 2026.
This Delta deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/65:30 am
TYS
- HOU
1 stop4h 45m
Delta
Wed 9/161:00 pm
HOU
- TYS
1 stop4h 17m
Delta
Deal found 3/20![Delta logo]()
$267
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1511:25 am
TYS
- IAH
Nonstop2h 41m
United Airlines
Wed 4/222:55 pm
IAH
- TYS
Nonstop2h 20m
United Airlines
Deal found 3/18![United Airlines logo]()
$291
This Southwest deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:40 am
TYS
- HOU
2 stops8h 15m
Southwest
Sat 4/188:10 am
HOU
- TYS
2 stops9h 20m
Southwest
Deal found 3/15![Southwest logo]()
$299
This Delta deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/54:00 pm
TYS
- HOU
1 stop6h 35m
Delta
Wed 9/1610:05 am
HOU
- TYS
1 stop4h 02m
Delta
Deal found 3/20![Delta logo]()
$267
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:40 am
TYS
- HOU
2 stops8h 15m
Southwest
Sat 4/258:20 am
HOU
- TYS
2 stops9h 10m
Southwest
Deal found 3/19![Southwest logo]()
$299
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/237:15 am
TYS
- IAH
Nonstop2h 25m
United Airlines
Sun 5/317:50 pm
IAH
- TYS
Nonstop2h 22m
United Airlines
Deal found 3/17![United Airlines logo]()
$307
This Delta deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/215:54 pm
TYS
- HOU
1 stop6h 13m
Delta
Tue 4/285:23 pm
HOU
- TYS
1 stop5h 31m
Delta
Deal found 3/20![Delta logo]()
$289
This United Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/29:00 am
TYS
- IAH
Nonstop2h 37m
United Airlines
Sat 4/44:40 pm
IAH
- TYS
Nonstop2h 16m
United Airlines
Deal found 3/16![United Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/54:00 pm
TYS
- HOU
1 stop6h 35m
Delta
Wed 9/91:00 pm
HOU
- TYS
1 stop4h 17m
Delta
Deal found 3/17![Delta logo]()
$289
This Southwest deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:35 am
TYS
- HOU
2 stops6h 10m
Southwest
Sun 4/196:10 am
HOU
- TYS
1 stop8h 05m
Southwest
Deal found 3/16![Southwest logo]()
$348
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/214:38 pm
TYS
- IAH
1 stop5h 57m
Delta
Tue 4/289:43 am
IAH
- TYS
1 stop5h 09m
Delta
Deal found 3/19![Delta logo]()
$289
This United Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/219:00 am
TYS
- IAH
Nonstop2h 37m
United Airlines
Sat 4/258:21 pm
IAH
- TYS
Nonstop2h 20m
United Airlines
Deal found 3/15![United Airlines logo]()
$339
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/157:05 am
TYS
- HOU
1 stop4h 25m
Southwest
Wed 4/2210:25 am
HOU
- TYS
2 stops8h 15m
Southwest
Deal found 3/18![Southwest logo]()
$348
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/211:40 am
TYS
- IAH
Nonstop2h 37m
United Airlines
Tue 5/128:24 pm
IAH
- TYS
Nonstop2h 20m
United Airlines
Deal found 3/17![United Airlines logo]()
$339
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:35 am
TYS
- HOU
1 stop4h 20m
Southwest
Sat 4/410:25 am
HOU
- TYS
2 stops9h 40m
Southwest
Deal found 3/18![Southwest logo]()
$369
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:35 am
TYS
- HOU
2 stops7h 15m
Southwest
Mon 4/272:20 pm
HOU
- TYS
2 stops5h 00m
Southwest
Deal found 3/18![Southwest logo]()
$373
This United Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/203:40 pm
TYS
- IAH
Nonstop2h 41m
United Airlines
Sat 5/237:50 pm
IAH
- TYS
Nonstop2h 22m
United Airlines
Deal found 3/15![United Airlines logo]()
$384
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/285:13 pm
TYS
- IAH
1 stop5h 19m
Delta
Wed 4/17:00 am
IAH
- TYS
1 stop6h 32m
Delta
Deal found 3/19![Delta logo]()
$399
This Southwest deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/316:35 am
TYS
- HOU
2 stops8h 40m
Southwest
Sat 4/410:25 am
HOU
- TYS
2 stops9h 40m
Southwest
Deal found 3/15![Southwest logo]()
$374
This United Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/97:05 am
TYS
- IAH
Nonstop2h 41m
United Airlines
Sun 4/128:21 pm
IAH
- TYS
Nonstop2h 20m
United Airlines
Deal found 3/16![United Airlines logo]()
$384
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/297:15 am
TYS
- IAH
Nonstop2h 25m
United Airlines
Mon 6/15:05 pm
IAH
- TYS
1 stop6h 25m
United Airlines
Deal found 3/19![United Airlines logo]()
$398
Last-minute flights from Knoxville to HoustonDiscover last-minute flight deals from Knoxville to Houston. Data last updated March 20, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Houston. Data last updated March 20, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/302:06 pm
TYS
- IAH
1 stop20h 39m
Multiple Airlines
Tue 3/319:15 pm
IAH
- TYS
1 stop14h 30m
Multiple Airlines
Deal found 3/19![Multiple Airlines logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/303:29 pm
TYS
- IAH
1 stop19h 16m
Multiple Airlines
Wed 4/112:46 pm
IAH
- TYS
1 stop25h 25m
Multiple Airlines
Deal found 3/18![Multiple Airlines logo]()
$236
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/18:30 am
TYS
- IAH
1 stop15h 04m
Multiple Airlines
Sun 4/511:32 am
IAH
- TYS
1 stop11h 07m
Multiple Airlines
Deal found 3/15![Multiple Airlines logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:10 pm
TYS
- IAH
1 stop26h 03m
Multiple Airlines
Sun 4/1211:51 am
IAH
- TYS
1 stop9h 42m
Multiple Airlines
Deal found 3/16![Multiple Airlines logo]()
$233
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:10 pm
TYS
- IAH
1 stop26h 03m
Multiple Airlines
Mon 4/1311:15 am
IAH
- TYS
1 stop10h 09m
Multiple Airlines
Deal found 3/16![Multiple Airlines logo]()
$251
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:54 pm
TYS
- HOU
1 stop5h 53m
American Airlines
Wed 4/156:01 am
HOU
- TYS
1 stop5h 29m
American Airlines
Deal found 3/15![American Airlines logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:20 pm
TYS
- IAH
1 stop15h 18m
Multiple Airlines
Mon 4/207:48 pm
IAH
- TYS
1 stop12h 52m
Multiple Airlines
Deal found 3/16![Multiple Airlines logo]()
$238
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/154:25 pm
TYS
- IAH
1 stop7h 22m
Multiple Airlines
Wed 4/226:05 am
IAH
- TYS
2 stops32h 36m
Multiple Airlines
Deal found 3/18![Multiple Airlines logo]()
$216
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/169:32 pm
TYS
- IAH
1 stop18h 14m
Multiple Airlines
Mon 4/207:48 pm
IAH
- TYS
1 stop12h 52m
Multiple Airlines
Deal found 3/17![Multiple Airlines logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/181:59 pm
TYS
- IAH
2 stops22h 28m
Multiple Airlines
Mon 4/207:48 pm
IAH
- TYS
1 stop12h 52m
Multiple Airlines
Deal found 3/17![Multiple Airlines logo]()
$253
This Priceline deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/304:28 pm
TYS
- IAH
1 stop9h 20m
Frontier
Sun 5/36:45 am
IAH
- TYS
1 stop7h 48m
Frontier
Deal found 3/20![Frontier logo]()
$181
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3011:27 am
TYS
- IAH
2 stops21h 32m
Multiple Airlines
Sun 5/39:46 am
IAH
- TYS
1 stop9h 49m
Multiple Airlines
Deal found 3/20![Multiple Airlines logo]()
$235
One-way flights from Knoxville to HoustonSearch for one-way flight options from Knoxville to Houston. Find affordable one-way fares based on user searches. Data last updated March 20, 2026.
Search for one-way flight options from Knoxville to Houston. Find affordable one-way fares based on user searches. Data last updated March 20, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:10 pm
TYS
- IAH
1 stop26h 03m
Multiple Airlines
Deal found 3/17![Multiple Airlines logo]()
$105
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/32:06 pm
TYS
- IAH
1 stop9h 31m
Multiple Airlines
Deal found 3/19![Multiple Airlines logo]()
$114
This Trip.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/266:55 pm
TYS
- IAH
1 stop24h 42m
Multiple Airlines
Deal found 3/17![Multiple Airlines logo]()
$131
This Southwest deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:40 am
TYS
- HOU
1 stop4h 25m
Southwest
Deal found 3/17![Southwest logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/311:27 am
TYS
- IAH
2 stops36h 23m
Multiple Airlines
Deal found 3/18![Multiple Airlines logo]()
$153
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:44 pm
TYS
- IAH
1 stop24h 29m
Multiple Airlines
Deal found 3/18![Multiple Airlines logo]()
$164
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/117:05 am
TYS
- IAH
Nonstop2h 41m
United Airlines
Deal found 3/17![United Airlines logo]()
$174
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/113:58 pm
TYS
- IAH
1 stop5h 38m
American Airlines
Deal found 3/17![American Airlines logo]()
$184
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/243:00 pm
TYS
- IAH
2 stops32h 56m
Multiple Airlines
Deal found 3/17![Multiple Airlines logo]()
$190
This Southwest deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/267:25 pm
TYS
- HOU
1 stop6h 20m
Southwest
Deal found 3/17![Southwest logo]()
$200
This American Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/266:21 pm
TYS
- HOU
1 stop6h 37m
American Airlines
Deal found 3/18![American Airlines logo]()
$279
Find flight deals from Knoxville to Houston
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Houston (HO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 20, 2026.
Round-trip from | $129 (Kiwi.com) |
|---|---|
One-way from | $105 (Kiwi.com) |
Popular in | March |
Cheapest in | August |
Average price | $424 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Houston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 20, 2026.
Use the filters below to find and compare flights from Knoxville to Houston that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleHouston
TYS - HOU
TYSHOU
Knoxville McGhee Tyson
Sun 9/6
5:30 am-9:15 am
1 stop4h 45m
Houston Hobby
Wed 9/16
1:00 pm-6:17 pm
1 stop4h 17m
$267
KnoxvilleHouston
TYS - HOU
TYSHOU
Knoxville McGhee Tyson
Sat 9/5
4:00 pm-9:35 pm
1 stop6h 35m
Houston Hobby
Wed 9/16
10:05 am-3:07 pm
1 stop4h 02m
$267
KnoxvilleHouston
TYS - HOU
TYSHOU
Knoxville McGhee Tyson
Tue 4/21
5:54 pm-11:07 pm
1 stop6h 13m
Houston Hobby
Tue 4/28
5:23 pm-11:54 pm
1 stop5h 31m
$289
KnoxvilleHouston
TYS - HOU
TYSHOU
Knoxville McGhee Tyson
Sat 9/5
4:00 pm-9:35 pm
1 stop6h 35m
Houston Hobby
Wed 9/9
1:00 pm-6:17 pm
1 stop4h 17m
$289
KnoxvilleHouston
TYS - IAH
TYSIAH
Knoxville McGhee Tyson
Tue 4/21
4:38 pm-9:35 pm
1 stop5h 57m
Houston George Bush Intcntl
Tue 4/28
9:43 am-3:52 pm
1 stop5h 09m
$289
KnoxvilleHouston
TYS - IAH
TYSIAH
Knoxville McGhee Tyson
Wed 4/15
11:25 am-1:06 pm
Nonstop2h 41m
Houston George Bush Intcntl
Wed 4/22
2:55 pm-6:15 pm
Nonstop2h 20m
$291
KnoxvilleHouston
TYS - HOU
TYSHOU
Knoxville McGhee Tyson
Sat 4/11
6:40 am-1:55 pm
2 stops8h 15m
Houston Hobby
Sat 4/18
8:10 am-6:30 pm
2 stops9h 20m
$299
KnoxvilleHouston
TYS - HOU
TYSHOU
Knoxville McGhee Tyson
Sat 4/18
6:40 am-1:55 pm
2 stops8h 15m
Houston Hobby
Sat 4/25
8:20 am-6:30 pm
2 stops9h 10m
$299
Quickest round-trip
KnoxvilleHouston
TYS - IAH
TYSIAH
Knoxville McGhee Tyson
Sat 5/23
7:15 am-8:40 am
Nonstop2h 25m
Houston George Bush Intcntl
Sun 5/31
7:50 pm-11:12 pm
Nonstop2h 22m
$307
KnoxvilleHouston
TYS - IAH
TYSIAH
Knoxville McGhee Tyson
Thu 4/2
9:00 am-10:37 am
Nonstop2h 37m
Houston George Bush Intcntl
Sat 4/4
4:40 pm-7:56 pm
Nonstop2h 16m
$309
Showing 1-10 of 35 resultsSorted by cheapest first
Best time to book a flight from Knoxville to Houston
Have a flexible travel schedule? Discover the best time to fly to Houston from Knoxville with our price prediction graph.
TYS-HO1
TYS-HOU
TYS-IAH
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Houston
TYS-HO1
TYS-HOU
TYS-IAH
How far ahead should I book a flight from Knoxville to Houston?
Use this chart to determine the optimal time to book a round-trip flight from Knoxville to Houston. Price data was last updated on March 13, 2026.
The best time to book flights from Knoxville to Houston is 81 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Knoxville to Houston?
Currently, June is the cheapest month in which you can book a flight from Knoxville to Houston (average of $57). Flying from Knoxville to Houston in March is currently the most expensive (average of $216). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from TYS to HOU?
Find hourly flight availability from Knoxville to Houston. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 20, 2026.
When flying from Knoxville to Houston, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
Reviews of airlines servicing Houston
Get insights into the airlines that provide service to Houston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Houston. Reviews last updated March 20, 2026.
See what other customers who have flown with Delta,United Airlines, andAllegiant Air from Knoxville to Houston have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.9
Food
7.2
Boarding
8.1
Crew
8.5
Entertainment
7.8
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Comfort
7.9
Food
7.2
Boarding
8.1
Crew
8.5
Entertainment
7.8
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Comfort
7.9
Food
7.2
Boarding
8.1
Crew
8.5
Entertainment
7.8
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Comfort
7.9
Food
7.2
Boarding
8.1
Crew
8.5
Entertainment
7.8
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Comfort
7.9
Food
7.2
Boarding
8.1
Crew
8.5
Entertainment
7.8
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Houston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Knoxville to Houston
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Complete your trip
Complete your trip to Houston by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Knoxville to Houston by cabin class
Find flights from Knoxville to Houston, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Knoxville and Houston flights
Browse other Knoxville and Houston flight options. Last updated on March 20, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on March 20, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from Knoxville to Houston
Discover the top 4 airlines that operate flights from Knoxville to Houston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 20, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$50 | Average$119 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$209 | Average$359 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$228 | Average$371 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$228 | Average$283 | FlexibilityNo cancel fee | On-timeN/A |