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$264+ Cheap flights from Florence, SC (FLO) to Houston

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/15. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — HOU
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
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Find flight deals from Florence to Houston

Cheapest flights from Florence to Houston
Explore the most affordable flight options available from Florence to Houston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/156:33 pmFLO - IAH
1 stop6h 45mAmerican Airlines
Mon 11/175:04 pmIAH - FLO
1 stop4h 49mAmerican Airlines
Deal found 10/27$264
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/155:15 amFLO - HOU
2 stops11h 39mAmerican Airlines
Mon 11/176:00 amHOU - FLO
2 stops10h 09mAmerican Airlines
Deal found 10/27$274
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/116:15 amFLO - HOU
2 stops10h 39mAmerican Airlines
Sat 11/1512:13 pmHOU - FLO
2 stops10h 54mAmerican Airlines
Deal found 10/27$289
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/286:33 pmFLO - IAH
1 stop6h 45mAmerican Airlines
Fri 12/55:12 pmIAH - FLO
1 stop4h 41mAmerican Airlines
Deal found 10/27$343
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/285:15 amFLO - HOU
2 stops11h 39mAmerican Airlines
Fri 12/55:44 amHOU - FLO
2 stops10h 26mAmerican Airlines
Deal found 10/27$568

Cheap flight deals from Florence to Houston

Discover tips and strategies to find the most affordable flight options for your journey from Florence (FLO) to Houston (HO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 29, 2025.

Round-trip from

$264
(American Airlines)
From Florence to Houston
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Florence to Houston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Florence to Houston that are best for you.

Fly from

Florence

Fly to

Houston

Route

Depart

Return

Price

FlorenceHouston

FLO - IAH

FLOIAH

Florence

Sat 11/15

6:33 pm-12:18 am

1 stop6h 45m

Houston George Bush Intcntl

Mon 11/17

5:04 pm-10:53 pm

1 stop4h 49m

$264

FlorenceHouston

FLO - HOU

FLOHOU

Florence

Sat 11/15

5:15 am-3:54 pm

2 stops11h 39m

Houston Hobby

Mon 11/17

6:00 am-5:09 pm

2 stops10h 09m

$274

FlorenceHouston

FLO - HOU

FLOHOU

Florence

Tue 11/11

6:15 am-3:54 pm

2 stops10h 39m

Houston Hobby

Sat 11/15

12:13 pm-12:07 am

2 stops10h 54m

$289

FlorenceHouston

FLO - IAH

FLOIAH

Florence

Sat 2/28

5:15 am-11:25 am

1 stop7h 10m

Houston George Bush Intcntl

Wed 3/4

11:18 am-5:23 pm

1 stop5h 05m

$319

FlorenceHouston

FLO - IAH

FLOIAH

Florence

Fri 11/28

6:33 pm-12:18 am

1 stop6h 45m

Houston George Bush Intcntl

Fri 12/5

5:12 pm-10:53 pm

1 stop4h 41m

$343

FlorenceHouston

FLO - IAH

FLOIAH

Florence

Tue 3/10

11:09 am-4:19 pm

1 stop6h 10m

Houston George Bush Intcntl

Sat 3/14

7:05 am-2:05 pm

1 stop6h 00m

$453

FlorenceHouston

FLO - HOU

FLOHOU

Florence

Sat 2/28

5:15 am-11:46 am

2 stops7h 31m

Houston Hobby

Wed 3/4

12:16 pm-11:10 pm

2 stops9h 54m

$541

FlorenceHouston

FLO - HOU

FLOHOU

Florence

Tue 11/4

11:14 am-8:20 pm

2 stops10h 06m

$386

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/27

Best time to book a flight from Florence to Houston

Have a flexible travel schedule? Discover the best time to fly to Houston from Florence with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florence to Houston

What is the cheapest month to book a flight from Florence, South Carolina to Houston?

Currently, September is the cheapest month in which you can book a flight from Florence, South Carolina to Houston (average of $44). Flying from Florence, South Carolina to Houston in July is currently the most expensive (average of $129). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Houston

Get insights into the airlines that provide service to Houston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Houston. Reviews last updated October 29, 2025.
See what other customers who have flown with American Airlines from Florence to Houston have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,030 reviews

Crew

8.0

Food

6.4

Boarding

7.5

Entertainment

6.9

Overall

7.2

Comfort

7.2

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2025

PIT - DFW

Due to gate changes,we nearly missed our flight. The gate agent reassigned our seats and would NOT give us our assigned seats,but she did honor that same request to the man who arrived after us. Her rudeness and difficulty was not appropriate.
American Airlines
7.2
Good
11,030 reviews
American Airlines
7.2
Good
11,030 reviews

Crew

8.0

Food

6.4

Boarding

7.5

Entertainment

6.9

Overall

7.2

Comfort

7.2

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2025

PIT - DFW

Due to gate changes,we nearly missed our flight. The gate agent reassigned our seats and would NOT give us our assigned seats,but she did honor that same request to the man who arrived after us. Her rudeness and difficulty was not appropriate.

Related info for your journey

Find useful and relevant information for your journey from Florence to Houston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Florence to Houston?

    For a flight from Florence to Houston, you will be flying from Florence. Florence (FLO) is just 2.3 mi from the center of the city. Florence is the only Florence airport and it handles 0 outbound flights to Houston per day. 1 airline has flights to Houston from Florence on a regular basis.

  • How long is the flight from Florence, South Carolina to Houston?

    Airlines like American Airlines fly from Florence, South Carolina to Houston in about 6h 45m. The time it takes to get you to your destination can typically vary by up to . Airlines will cover a distance of 957 mi.

  • Can I find deals for flights from Florence to Houston that include hotel bookings?

    Yes. In addition to deals on Florence to Houston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florence to Houston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to Houston.

  • Can I find deals for business class flights from Florence to Houston?

    Yes. Cheapflights offers flight deals from Florence to Houston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Florence, South Carolina to Houston?

    Currently, September is the cheapest month in which you can book a flight from Florence, South Carolina to Houston (average of $44). Flying from Florence, South Carolina to Houston in July is currently the most expensive (average of $129). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top airline flying from Florence to Houston

Discover the top airline that operate flights from Florence to Houston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$254Average$428FlexibilityNo cancel feeOn-time71%

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