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$264+ Cheap flights from Florence, SC (FLO) to Houston

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/27. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — HOU
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Florence to Houston

Discover tips and strategies to find the most affordable flight options for your journey from Florence (FLO) to Houston (HO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$264
(American Airlines)
From Florence to Houston
Search Deals

Find flight deals from Florence to Houston

Cheapest flights from Florence to Houston
Explore the most affordable flight options available from Florence to Houston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/275:37 pmFLO - IAH
1 stop5h 48mAmerican Airlines
Tue 9/3011:00 amIAH - FLO
1 stop5h 12mAmerican Airlines
Deal found 9/9$264
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2612:27 pmFLO - HOU
2 stops8h 44mAmerican Airlines
Tue 9/302:33 pmHOU - FLO
2 stops7h 43mAmerican Airlines
Deal found 9/11$289
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/195:37 pmFLO - IAH
1 stop5h 48mAmerican Airlines
Sun 9/218:20 amIAH - FLO
1 stop7h 12mAmerican Airlines
Deal found 9/10$369
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1912:27 pmFLO - HOU
2 stops8h 44mAmerican Airlines
Sun 9/216:00 amHOU - FLO
2 stops9h 32mAmerican Airlines
Deal found 9/10$379
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/145:14 amFLO - IAH
1 stop4h 40mAmerican Airlines
Tue 9/169:00 amIAH - FLO
1 stop7h 12mAmerican Airlines
Deal found 9/10$767
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/145:14 amFLO - HOU
2 stops9h 47mAmerican Airlines
Tue 9/162:33 pmHOU - FLO
2 stops7h 43mAmerican Airlines
Deal found 9/10$777

Cheapflights Fare Finder

 
Customize your flight search to find flights from Florence to Houston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Florence to Houston that are best for you.

Fly from

Florence

Fly to

Houston

Route

Depart

Return

Price

FlorenceHouston

FLO - IAH

FLOIAH

Florence

Sat 9/27

5:37 pm-10:25 pm

1 stop5h 48m

Houston George Bush Intcntl

Tue 9/30

11:00 am-5:12 pm

1 stop5h 12m

$264

FlorenceHouston

FLO - HOU

FLOHOU

Florence

Fri 9/26

12:27 pm-8:11 pm

2 stops8h 44m

Houston Hobby

Tue 9/30

2:33 pm-11:16 pm

2 stops7h 43m

$289

FlorenceHouston

FLO - IAH

FLOIAH

Florence

Fri 9/19

6:14 am-10:08 am

1 stop4h 54m

Houston George Bush Intcntl

Sun 9/21

9:44 am-4:32 pm

1 stop5h 48m

$369

FlorenceHouston

FLO - IAH

FLOIAH

Florence

Fri 9/19

5:37 pm-10:25 pm

1 stop5h 48m

Houston George Bush Intcntl

Mon 9/22

5:00 am-5:12 pm

2 stops11h 12m

$374

FlorenceHouston

FLO - HOU

FLOHOU

Florence

Sat 2/28

2:33 pm-11:40 pm

2 stops10h 07m

Houston Hobby

Wed 3/4

6:04 am-2:03 pm

2 stops6h 59m

$476

FlorenceHouston

FLO - IAH

FLOIAH

Florence

Sun 9/14

4:57 pm-11:19 pm

1 stop7h 22m

Houston George Bush Intcntl

Tue 9/16

11:00 am-5:12 pm

1 stop5h 12m

$767

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/9

Best time to book a flight from Florence to Houston

Have a flexible travel schedule? Discover the best time to fly to Houston from Florence with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florence to Houston

What is the cheapest month to book a flight from Florence, South Carolina to Houston?

Currently, September is the cheapest month in which you can book a flight from Florence, South Carolina to Houston (average of $230). Flying from Florence, South Carolina to Houston in March is currently the most expensive (average of $331). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Houston

Get insights into the airlines that provide service to Houston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Houston. Reviews last updated September 11, 2025.
See what other customers who have flown with American Airlines from Florence to Houston have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Food

6.4

Overall

7.2

Comfort

7.2

Boarding

7.5

Crew

8.0

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2025

PIT - DFW

Due to gate changes,we nearly missed our flight. The gate agent reassigned our seats and would NOT give us our assigned seats,but she did honor that same request to the man who arrived after us. Her rudeness and difficulty was not appropriate.
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Food

6.4

Overall

7.2

Comfort

7.2

Boarding

7.5

Crew

8.0

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2025

PIT - DFW

Due to gate changes,we nearly missed our flight. The gate agent reassigned our seats and would NOT give us our assigned seats,but she did honor that same request to the man who arrived after us. Her rudeness and difficulty was not appropriate.

Related info for your journey

Find useful and relevant information for your journey from Florence to Houston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Florence to Houston?

    For a flight from Florence to Houston, you will be flying from Florence. Florence (FLO) is just 2.3 mi from the center of the city. Florence is the only Florence airport and it handles 0 outbound flights to Houston per day. 1 airline has flights to Houston from Florence on a regular basis.

  • How long is the flight from Florence, South Carolina to Houston?

    Airlines like American Airlines fly from Florence, South Carolina to Houston in about 5h 48m. The time it takes to get you to your destination can typically vary by up to . Airlines will cover a distance of 957 mi.

  • Can I find deals for flights from Florence to Houston that include hotel bookings?

    Yes. In addition to deals on Florence to Houston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florence to Houston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to Houston.

  • Can I find deals for business class flights from Florence to Houston?

    Yes. Cheapflights offers flight deals from Florence to Houston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Florence, South Carolina to Houston?

    Currently, September is the cheapest month in which you can book a flight from Florence, South Carolina to Houston (average of $230). Flying from Florence, South Carolina to Houston in March is currently the most expensive (average of $331). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top airline flying from Florence to Houston

Discover the top airline that operate flights from Florence to Houston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$341Average$428FlexibilityNo cancel feeOn-time71%

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