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$249+ Cheap flights from Florence, SC (FLO) to Houston

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/16. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — HOU
Mar 23 — Mar 301
Mon 3/23
Mon 3/30
1 adult, Economy
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Cheap flight deals from Florence to Houston

Cheapest flights from Florence to Houston
Explore the most affordable flight options available from Florence to Houston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 21, 2026.

This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/165:20 am
FLO
-
IAH
1 stop4h 53m
American Airlines
Mon 4/203:22 pm
IAH
-
FLO
1 stop7h 30m
American Airlines
Deal found 2/19$249
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/165:20 am
FLO
-
IAH
1 stop4h 53m
American Airlines
Sun 4/196:12 pm
IAH
-
FLO
1 stop4h 40m
American Airlines
Deal found 2/20$353
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/246:15 am
FLO
-
IAH
1 stop5h 11m
American Airlines
Sat 2/2812:07 pm
IAH
-
FLO
1 stop4h 43m
American Airlines
Deal found 2/19$444
This American Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/235:16 am
FLO
-
IAH
1 stop5h 05m
American Airlines
Mon 3/306:16 pm
IAH
-
FLO
1 stop4h 41m
American Airlines
Deal found 2/21$457
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/246:15 am
FLO
-
HOU
2 stops10h 36m
American Airlines
Sat 2/286:00 am
HOU
-
FLO
2 stops10h 50m
American Airlines
Deal found 2/20$472
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/205:16 am
FLO
-
IAH
1 stop7h 00m
American Airlines
Tue 2/2411:16 am
IAH
-
FLO
1 stop5h 05m
American Airlines
Deal found 2/18$514
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/205:16 am
FLO
-
HOU
2 stops11h 35m
American Airlines
Tue 2/246:00 am
HOU
-
FLO
2 stops10h 21m
American Airlines
Deal found 2/19$524
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/65:16 am
FLO
-
HOU
2 stops7h 32m
American Airlines
Tue 3/106:00 am
HOU
-
FLO
2 stops10h 21m
American Airlines
Deal found 2/19$532
This American Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/135:16 am
FLO
-
IAH
1 stop5h 05m
American Airlines
Sun 3/156:16 pm
IAH
-
FLO
1 stop4h 41m
American Airlines
Deal found 2/17$613
This American Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/135:16 am
FLO
-
HOU
2 stops7h 32m
American Airlines
Sun 3/156:00 am
HOU
-
FLO
2 stops10h 50m
American Airlines
Deal found 2/17$813
This American Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/235:16 am
FLO
-
HOU
2 stops7h 32m
American Airlines
Mon 3/3012:18 pm
HOU
-
FLO
2 stops10h 39m
American Airlines
Deal found 2/21$826

Find flight deals from Florence to Houston

Discover tips and strategies to find the most affordable flight options for your journey from Florence (FLO) to Houston (HO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 21, 2026.

Round-trip from

$249
(American Airlines)
From Florence to Houston
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Florence to Houston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 21, 2026.
Use the filters below to find and compare flights from Florence to Houston that are best for you.

Fly from

Florence

Fly to

Houston

Route

Depart

Return

Price

FlorenceHouston

FLO - IAH

FLOIAH

Florence

Thu 4/16

5:20 am-9:13 am

1 stop4h 53m

Houston George Bush Intcntl

Mon 4/20

3:22 pm-11:52 pm

1 stop7h 30m

$249

FlorenceHouston

FLO - IAH

FLOIAH

Florence

Thu 4/16

5:20 am-9:13 am

1 stop4h 53m

Houston George Bush Intcntl

Sun 4/19

6:12 pm-11:52 pm

1 stop4h 40m

$353

FlorenceHouston

FLO - IAH

FLOIAH

Florence

Mon 3/23

5:16 am-9:21 am

1 stop5h 05m

Houston George Bush Intcntl

Mon 3/30

6:16 pm-11:57 pm

1 stop4h 41m

$457

FlorenceHouston

FLO - HOU

FLOHOU

Florence

Fri 3/6

5:16 am-11:48 am

2 stops7h 32m

Houston Hobby

Tue 3/10

6:00 am-5:21 pm

2 stops10h 21m

$532

FlorenceHouston

FLO - IAH

FLOIAH

Florence

Fri 3/13

5:16 am-9:21 am

1 stop5h 05m

Houston George Bush Intcntl

Sun 3/15

6:16 pm-11:57 pm

1 stop4h 41m

$613

FlorenceHouston

FLO - HOU

FLOHOU

Florence

Fri 3/13

5:16 am-11:48 am

2 stops7h 32m

Houston Hobby

Sun 3/15

6:00 am-5:50 pm

2 stops10h 50m

$813

FlorenceHouston

FLO - HOU

FLOHOU

Florence

Mon 3/23

5:16 am-11:48 am

2 stops7h 32m

Houston Hobby

Mon 3/30

12:18 pm-11:57 pm

2 stops10h 39m

$826

FlorenceHouston

FLO - IAH

FLOIAH

Florence

Fri 3/6

5:16 am-9:27 am

1 stop5h 11m

$427

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/20

Best time to book a flight from Florence to Houston

Have a flexible travel schedule? Discover the best time to fly to Houston from Florence with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florence to Houston

What is the cheapest month to book a flight from Florence, South Carolina to Houston?

Currently, September is the cheapest month in which you can book a flight from Florence, South Carolina to Houston (average of $44). Flying from Florence, South Carolina to Houston in July is currently the most expensive (average of $129). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Florence to Houston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Florence to Houston?

    For a flight from Florence to Houston, you will be flying from Florence. Florence (FLO) is just 2.3 mi from the center of the city. Florence is the only Florence airport and it handles 0 outbound flights to Houston per day. 0 airlines have flights to Houston from Florence on a regular basis.

  • How long is the flight from Florence, South Carolina to Houston?

    Airlines like American Airlines fly from Florence, South Carolina to Houston in about 4h 53m. The time it takes to get you to your destination can typically vary by up to . Airlines will cover a distance of 957 mi.

  • Can I find deals for flights from Florence to Houston that include hotel bookings?

    Yes. In addition to deals on Florence to Houston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florence to Houston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to Houston.

  • Can I find deals for business class flights from Florence to Houston?

    Yes. Cheapflights offers flight deals from Florence to Houston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Florence, South Carolina to Houston?

    Currently, September is the cheapest month in which you can book a flight from Florence, South Carolina to Houston (average of $44). Flying from Florence, South Carolina to Houston in July is currently the most expensive (average of $129). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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