$156+ Cheap flights from Knoxville to Harrisburg (TYS - MDT)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MDT
Sep 28 — Oct 51
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Knoxville to Harrisburg with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Harrisburg
Cheapest
Best
Last-minute
One-way
Cheapest flights from Knoxville to HarrisburgExplore the most affordable flight options available from Knoxville to Harrisburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 29, 2026.
Explore the most affordable flight options available from Knoxville to Harrisburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 29, 2026.
This Delta deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:40 am -
1 stop5h 23m
Mon 10/55:58 pm -
1 stop5h 57m
Deal found 8/24![Delta logo]()
$299
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:00 am -
2 stops7h 59m
Sat 10/32:08 pm -
1 stop6h 41m
Deal found 8/27![United Airlines logo]()
$304
This Delta deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3010:26 am -
1 stop6h 42m
Wed 10/711:44 am -
1 stop3h 42m
Deal found 8/24![Delta logo]()
$323
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/29:56 pm -
1 stop13h 07m
Mon 10/53:38 pm -
1 stop5h 00m
Deal found 8/24![Allegiant Air logo]()
$368
This American Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:15 am -
1 stop4h 02m
Mon 10/512:18 pm -
1 stop5h 17m
Deal found 8/24![American Airlines logo]()
$369
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3010:28 am -
2 stops22h 25m
Mon 10/53:38 pm -
1 stop5h 00m
Deal found 8/24![Multiple Airlines logo]()
$373
This Kiwi.com deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2612:54 pm -
1 stop5h 48m
Thu 10/298:51 pm -
1 stop24h 50m
Deal found 8/27![Allegiant Air logo]()
$385
This American Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/278:12 am -
1 stop4h 06m
Sun 8/305:00 am -
1 stop5h 30m
Deal found 8/26![American Airlines logo]()
$389
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/117:20 pm -
1 stop4h 10m
Tue 9/157:59 pm -
1 stop4h 00m
Deal found 8/27![United Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:40 am -
1 stop6h 04m
Sat 9/266:09 pm -
1 stop4h 18m
Deal found 8/24![Delta logo]()
$407
This American Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:15 am -
1 stop4h 02m
Wed 10/712:18 pm -
1 stop5h 17m
Deal found 8/24![American Airlines logo]()
$413
Best flights from Knoxville to HarrisburgDiscover carefully curated flight deals from Knoxville to Harrisburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 29, 2026.
Discover carefully curated flight deals from Knoxville to Harrisburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 29, 2026.
This Delta deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:40 am -
1 stop5h 23m
Mon 10/55:58 pm -
1 stop5h 57m
Deal found 8/24![Delta logo]()
$299
This United Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/77:00 am -
1 stop6h 37m
Mon 1/116:00 am -
1 stop4h 00m
Deal found 8/25![United Airlines logo]()
$408
This American Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:15 am -
1 stop4h 02m
Wed 10/712:18 pm -
1 stop5h 17m
Deal found 8/24![American Airlines logo]()
$413
This Delta deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:40 am -
1 stop5h 23m
Tue 10/65:10 pm -
1 stop4h 27m
Deal found 8/24![Delta logo]()
$299
This United Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/91:53 pm -
2 stops9h 37m
Sun 9/135:54 pm -
1 stop4h 55m
Deal found 8/25![United Airlines logo]()
$434
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:00 am -
2 stops7h 39m
Tue 9/152:52 pm -
2 stops9h 31m
Deal found 8/27![United Airlines logo]()
$473
Last-minute flights from Knoxville to HarrisburgDiscover last-minute flight deals from Knoxville to Harrisburg. Data last updated August 29, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Harrisburg. Data last updated August 29, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/97:20 pm -
1 stop4h 10m
Sun 9/135:54 pm -
1 stop4h 55m
Deal found 8/25![United Airlines logo]()
$429
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/117:20 pm -
1 stop4h 10m
Tue 9/157:59 pm -
1 stop4h 00m
Deal found 8/27![United Airlines logo]()
$399
This United Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:00 am -
1 stop7h 30m
Wed 9/302:08 pm -
1 stop6h 41m
Deal found 8/26![United Airlines logo]()
$448
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:00 am -
2 stops7h 59m
Sat 10/32:08 pm -
1 stop6h 41m
Deal found 8/27![United Airlines logo]()
$304
This Delta deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:40 am -
1 stop6h 04m
Sat 9/266:09 pm -
1 stop4h 18m
Deal found 8/24![Delta logo]()
$407
This Delta deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:40 am -
1 stop5h 23m
Mon 10/55:58 pm -
1 stop5h 57m
Deal found 8/24![Delta logo]()
$299
This Delta deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3010:26 am -
1 stop6h 42m
Wed 10/711:44 am -
1 stop3h 42m
Deal found 8/24![Delta logo]()
$323
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3010:28 am -
2 stops22h 25m
Mon 10/53:38 pm -
1 stop5h 00m
Deal found 8/24![Multiple Airlines logo]()
$373
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3010:28 am -
2 stops22h 25m
Wed 10/72:09 pm -
1 stop8h 32m
Deal found 8/24![Multiple Airlines logo]()
$430
One-way flights from Knoxville to HarrisburgSearch for one-way flight options from Knoxville to Harrisburg. Find affordable one-way fares based on user searches. Data last updated August 29, 2026.
Search for one-way flight options from Knoxville to Harrisburg. Find affordable one-way fares based on user searches. Data last updated August 29, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2110:55 am -
1 stop22h 25m
Deal found 8/26![Allegiant Air logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/11:37 pm -
3 stops45h 26m
Deal found 8/24![Multiple Airlines logo]()
$176
This Kiwi.com deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/202:52 pm -
1 stop22h 27m
Deal found 8/26![Allegiant Air logo]()
$186
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:23 pm -
1 stop24h 03m
Deal found 8/24![Allegiant Air logo]()
$203
This Delta deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/307:33 am -
1 stop4h 02m
Deal found 8/24![Delta logo]()
$204
This United Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:00 am -
2 stops7h 59m
Deal found 8/26![United Airlines logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:43 pm -
3 stops41h 40m
Deal found 8/26![Multiple Airlines logo]()
$217
This United Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:00 am -
2 stops7h 59m
Deal found 8/24![United Airlines logo]()
$244
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:11 pm -
1 stop5h 00m
Deal found 8/27![American Airlines logo]()
$259
This Kiwi.com deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/38:00 am -
1 stop24h 23m
Deal found 8/27![Allegiant Air logo]()
$266
Find flight deals from Knoxville to Harrisburg
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Harrisburg (MDT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $299 (Delta) |
One-way from | $156 (Kiwi.com) |
Popular in | May |
Cheapest in | December |
Average price | $692 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Harrisburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 29, 2026.
Use the filters below to find and compare flights from Knoxville to Harrisburg that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleHarrisburg
TYS Knoxville McGhee Tyson - MDT Harrisburg
TYSMDT
Knoxville McGhee Tyson
Wed 9/30
5:40 am-11:03 am
1 stop5h 23m
Harrisburg
Mon 10/5
5:58 pm-11:55 pm
1 stop5h 57m
$299
KnoxvilleHarrisburg
TYS Knoxville McGhee Tyson - MDT Harrisburg
TYSMDT
Knoxville McGhee Tyson
Wed 9/30
5:40 am-11:03 am
1 stop5h 23m
Harrisburg
Tue 10/6
5:10 pm-9:37 pm
1 stop4h 27m
$299
KnoxvilleHarrisburg
TYS Knoxville McGhee Tyson - MDT Harrisburg
TYSMDT
Knoxville McGhee Tyson
Thu 1/7
7:00 am-1:37 pm
1 stop6h 37m
Harrisburg
Mon 1/11
6:00 am-10:00 am
1 stop4h 00m
$408
Quickest round-trip
KnoxvilleHarrisburg
TYS Knoxville McGhee Tyson - MDT Harrisburg
TYSMDT
Knoxville McGhee Tyson
Thu 10/1
6:15 am-10:17 am
1 stop4h 02m
Harrisburg
Wed 10/7
12:18 pm-5:35 pm
1 stop5h 17m
$413
KnoxvilleHarrisburg
TYS Knoxville McGhee Tyson - MDT Harrisburg
TYSMDT
Knoxville McGhee Tyson
Wed 9/9
1:53 pm-11:30 pm
2 stops9h 37m
Harrisburg
Sun 9/13
5:54 pm-10:49 pm
1 stop4h 55m
$434
KnoxvilleHarrisburg
TYS Knoxville McGhee Tyson - MDT Harrisburg
TYSMDT
Knoxville McGhee Tyson
Fri 9/11
6:00 am-1:39 pm
2 stops7h 39m
Harrisburg
Tue 9/15
2:52 pm-12:23 am
2 stops9h 31m
$473
Cheapest one-way
KnoxvilleHarrisburg
TYS Knoxville McGhee Tyson - MDT Harrisburg
TYSMDT
Knoxville McGhee Tyson
Tue 10/20
2:52 pm-1:19 pm
1 stop22h 27m
$186
KnoxvilleHarrisburg
TYS Knoxville McGhee Tyson - MDT Harrisburg
TYSMDT
Knoxville McGhee Tyson
Thu 10/1
8:23 pm-8:26 pm
1 stop24h 03m
$203
KnoxvilleHarrisburg
TYS Knoxville McGhee Tyson - MDT Harrisburg
TYSMDT
Knoxville McGhee Tyson
Thu 10/1
10:26 am-5:08 pm
1 stop6h 42m
$204
KnoxvilleHarrisburg
TYS Knoxville McGhee Tyson - MDT Harrisburg
TYSMDT
Knoxville McGhee Tyson
Tue 10/20
6:00 am-1:59 pm
2 stops7h 59m
$209
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Knoxville to Harrisburg
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Harrisburg in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-Harrisburg flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Harrisburg flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Harrisburg flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-Harrisburg flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Harrisburg flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to Harrisburg
Have a flexible travel schedule? Discover the best time to fly to Harrisburg from Knoxville with our price prediction graph.
TYS-MDT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Harrisburg
What is the cheapest month to book a flight from Knoxville to Harrisburg?
Currently, December is the cheapest month in which you can book a flight from Knoxville to Harrisburg (average of $321). Flying from Knoxville to Harrisburg in May is currently the most expensive (average of $972). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Knoxville to Harrisburg?
Airfare is below average for this route at the moment.
Knoxville to Harrisburg flights typically cost between $513 and $1,007 in September.The cheapest round-trip price found within the last 5 days was $299 on Delta (Sep 30-Oct 5).
Reviews of airlines servicing Harrisburg
Get insights into the airlines that provide service to Harrisburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Harrisburg. Reviews last updated August 29, 2026.
Read reviews from past customers who have flown United Airlines and American Airlines from Knoxville to Harrisburg. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.3
Food
6.7
Boarding
7.7
Crew
8.1
Overall
7.4
Entertainment
7.1
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Comfort
7.3
Food
6.7
Boarding
7.7
Crew
8.1
Overall
7.4
Entertainment
7.1
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Comfort
7.3
Food
6.7
Boarding
7.7
Crew
8.1
Overall
7.4
Entertainment
7.1
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Harrisburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Harrisburg?
Book flights to Harrisburg if you plan to visit one of these locationsHershey
Mechanicsburg
Camp Hill
Carlisle
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Knoxville
Popular flights
Alternative routes for Knoxville to Harrisburg
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Harrisburg by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Knoxville to Harrisburg by cabin class
Find flights from Knoxville to Harrisburg, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Knoxville and Harrisburg flights
Browse other Knoxville and Harrisburg flight options. Last updated on August 29, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on August 29, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Knoxville to Harrisburg
Discover the top 2 airlines that operate flights from Knoxville to Harrisburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$282 | Average$584 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$309 | Average$489 | FlexibilityNo cancel fee | On-time69% |