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$149+ Cheap flights from Knoxville to Harrisburg (TYS - MDT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/5. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MDT
Mar 29 — Apr 51
Sun 3/29
Sun 4/5
1 adult, Economy
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Cheap flight deals from Knoxville to Harrisburg

Cheapest flights from Knoxville to Harrisburg
Explore the most affordable flight options available from Knoxville to Harrisburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 27, 2026.

This Delta deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/276:38 pm
TYS
-
MDT
1 stop5h 03m
Delta
Mon 3/306:32 pm
MDT
-
TYS
1 stop5h 25m
Delta
Deal found 2/24$249
This Kiwi.com deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/303:53 pm
TYS
-
MDT
1 stop17h 32m
Allegiant Air
Thu 8/69:12 pm
MDT
-
TYS
1 stop25h 32m
Allegiant Air
Deal found 2/24$314
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/182:05 pm
TYS
-
MDT
1 stop18h 19m
Allegiant Air
Sun 3/2210:37 am
MDT
-
TYS
1 stop21h 26m
Allegiant Air
Deal found 2/23$319
This United Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/308:20 am
TYS
-
MDT
2 stops10h 24m
United Airlines
Thu 8/67:59 pm
MDT
-
TYS
1 stop3h 55m
United Airlines
Deal found 2/24$334
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/277:40 am
TYS
-
MDT
1 stop8h 56m
Allegiant Air
Mon 3/304:13 pm
MDT
-
TYS
2 stops23h 53m
Allegiant Air
Deal found 2/23$369
This United Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/256:45 am
TYS
-
MDT
1 stop6h 42m
United Airlines
Sat 2/282:07 pm
MDT
-
TYS
1 stop6h 30m
United Airlines
Deal found 2/23$379
This United Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/286:45 am
TYS
-
MDT
1 stop6h 42m
United Airlines
Sun 3/12:07 pm
MDT
-
TYS
1 stop6h 30m
United Airlines
Deal found 2/23$416
This United Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/286:45 am
TYS
-
MDT
1 stop6h 42m
United Airlines
Wed 3/46:15 am
MDT
-
TYS
2 stops7h 00m
United Airlines
Deal found 2/26$467
This United Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/65:48 pm
TYS
-
MDT
1 stop6h 39m
United Airlines
Thu 4/96:15 am
MDT
-
TYS
1 stop4h 35m
United Airlines
Deal found 2/23$480

Find flight deals from Knoxville to Harrisburg

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Harrisburg (MDT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$249
(Delta)

One-way from

$149
(American Airlines)

Popular in

August

Cheapest in

December

Average price

$505
Provider with most accurate pricing for Knoxville McGhee Tyson-Harrisburg flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Harrisburg flights.
Search Deals
From Knoxville McGhee Tyson to Harrisburg
Search Deals
One-way flight from Knoxville McGhee Tyson to Harrisburg
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($59 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Harrisburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 27, 2026.
Use the filters below to find and compare flights from Knoxville to Harrisburg that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Fri 3/27

6:38 pm-11:41 pm

1 stop5h 03m

Harrisburg

Mon 3/30

6:32 pm-11:57 pm

1 stop5h 25m

$273

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Wed 3/18

2:05 pm-8:24 am

1 stop18h 19m

Harrisburg

Sun 3/22

10:37 am-8:03 am

1 stop21h 26m

$319

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Thu 7/30

8:20 am-6:44 pm

2 stops10h 24m

Harrisburg

Thu 8/6

7:59 pm-11:54 pm

1 stop3h 55m

$334

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Fri 3/27

7:40 am-4:36 pm

1 stop8h 56m

Harrisburg

Mon 3/30

4:13 pm-4:06 pm

2 stops23h 53m

$369

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Mon 4/6

5:48 pm-12:27 am

1 stop6h 39m

Harrisburg

Thu 4/9

6:15 am-10:50 am

1 stop4h 35m

$480

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Fri 3/27

5:43 pm-1:51 pm

2 stops20h 08m

Harrisburg

Mon 3/30

5:47 pm-10:29 pm

1 stop4h 42m

$518

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Sat 3/14

9:40 am-1:51 pm

1 stop4h 11m

Harrisburg

Wed 3/18

2:33 pm-7:29 pm

1 stop4h 56m

$538

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Tue 3/10

9:40 am-1:51 pm

1 stop4h 11m

Harrisburg

Fri 3/13

2:33 pm-10:49 am

1 stop20h 16m

$553

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Thu 3/12

7:00 am-1:27 pm

1 stop6h 27m

Harrisburg

Mon 3/16

6:15 am-1:18 pm

1 stop7h 03m

$568

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Wed 3/25

6:10 am-11:32 am

1 stop5h 22m

$159

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/24

Showing 1-10 of 16 resultsSorted by cheapest first
1
2

Compare providers for flights from Knoxville to Harrisburg

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Harrisburg in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Harrisburg flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Harrisburg flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Harrisburg flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Harrisburg flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Harrisburg flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Harrisburg

Have a flexible travel schedule? Discover the best time to fly to Harrisburg from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Harrisburg

What is the cheapest month to book a flight from Knoxville to Harrisburg?

Currently, August is the cheapest month in which you can book a flight from Knoxville to Harrisburg (average of $132). Flying from Knoxville to Harrisburg in December is currently the most expensive (average of $230). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Harrisburg

Get insights into the airlines that provide service to Harrisburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Harrisburg. Reviews last updated February 27, 2026.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Knoxville to Harrisburg. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,242 reviews

Comfort

7.9

Food

7.2

Overall

7.9

Entertainment

7.8

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,242 reviews
Delta
7.9
Good
8,242 reviews

Comfort

7.9

Food

7.2

Overall

7.9

Entertainment

7.8

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,349 reviews
Delta
7.9
Good
8,242 reviews

Comfort

7.9

Food

7.2

Overall

7.9

Entertainment

7.8

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,357 reviews
Delta
7.9
Good
8,242 reviews

Comfort

7.9

Food

7.2

Overall

7.9

Entertainment

7.8

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Harrisburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Harrisburg?

    A quick flight from Knoxville to Harrisburg can take about 5h 03m. Delta provides one of the quickest options available for as low as $273. The distance between Knoxville and Harrisburg is about 496 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Knoxville to Harrisburg round-trip?

    American Airlines, at $228, was found to be the cheapest airline from Knoxville to Harrisburg.Alternate airlines to your destination round-trip include Delta and United Airlines. American Airlines is 51% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Knoxville to Harrisburg that include hotel bookings?

    Yes. In addition to deals on Knoxville to Harrisburg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Harrisburg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Harrisburg.

  • Can I find deals for business class flights from Knoxville to Harrisburg?

    Yes. Cheapflights offers flight deals from Knoxville to Harrisburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Harrisburg?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to Harrisburg (average of $132). Flying from Knoxville to Harrisburg in December is currently the most expensive (average of $230). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Harrisburg?

Book flights to Harrisburg if you plan to visit one of these locations
Hershey
Mechanicsburg
Camp Hill
Carlisle

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See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Knoxville to Harrisburg

Discover the top 3 airlines that operate flights from Knoxville to Harrisburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$228Average$466FlexibilityNo cancel feeOn-time71%
DeltaCheapest$233Average$353FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$309Average$500FlexibilityNo cancel feeOn-time69%

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