$250+ Cheap flights from Knoxville to Harrisburg (TYS - MDT)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/13. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MDT
Dec 3 — Dec 101
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Harrisburg with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Harrisburg
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Cheapest flights from Knoxville to HarrisburgExplore the most affordable flight options available from Knoxville to Harrisburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 3, 2026.
Explore the most affordable flight options available from Knoxville to Harrisburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 3, 2026.
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/285:45 am -
1 stop4h 00m
Sat 12/52:50 pm -
1 stop4h 57m
Deal found 10/29![United Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/227:04 pm -
1 stop3h 45m
Sun 12/273:07 pm -
1 stop5h 50m
Deal found 11/3![American Airlines logo]()
$389
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/43:55 pm -
1 stop5h 04m
Sun 11/85:00 am -
1 stop5h 30m
Deal found 11/2![American Airlines logo]()
$409
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/228:01 pm -
1 stop4h 11m
Sat 12/267:52 am -
1 stop6h 22m
Deal found 11/3![American Airlines logo]()
$413
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/41:56 pm -
1 stop5h 01m
Sun 11/86:15 am -
2 stops10h 44m
Deal found 11/2![United Airlines logo]()
$414
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/171:56 pm -
1 stop5h 01m
Thu 1/76:20 am -
1 stop7h 00m
Deal found 11/1![United Airlines logo]()
$424
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/149:45 am -
1 stop4h 13m
Wed 11/188:15 am -
1 stop4h 58m
Deal found 10/30![United Airlines logo]()
$439
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:45 am -
2 stops7h 13m
Sat 11/216:15 am -
2 stops9h 37m
Deal found 11/2![United Airlines logo]()
$449
Best flights from Knoxville to HarrisburgDiscover carefully curated flight deals from Knoxville to Harrisburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 3, 2026.
Discover carefully curated flight deals from Knoxville to Harrisburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 3, 2026.
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/285:45 am -
1 stop4h 00m
Sat 12/52:50 pm -
1 stop4h 57m
Deal found 10/29![United Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/79:45 am -
1 stop4h 11m
Mon 1/118:35 am -
1 stop8h 19m
Deal found 11/2![United Airlines logo]()
$409
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:45 am -
2 stops7h 13m
Thu 1/76:20 am -
2 stops7h 00m
Deal found 11/1![United Airlines logo]()
$434
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:45 am -
2 stops7h 13m
Wed 11/188:15 am -
1 stop4h 58m
Deal found 10/30![United Airlines logo]()
$444
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:45 am -
2 stops7h 13m
Sat 11/216:15 am -
2 stops9h 37m
Deal found 11/2![United Airlines logo]()
$449
Last-minute flights from Knoxville to HarrisburgDiscover last-minute flight deals from Knoxville to Harrisburg. Data last updated November 3, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Harrisburg. Data last updated November 3, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/43:55 pm -
1 stop5h 04m
Sun 11/85:00 am -
1 stop5h 30m
Deal found 11/2![American Airlines logo]()
$409
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/41:56 pm -
1 stop5h 01m
Sun 11/86:15 am -
2 stops10h 44m
Deal found 11/2![United Airlines logo]()
$414
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/510:33 am -
1 stop6h 21m
Sun 11/88:13 pm -
1 stop3h 46m
Deal found 10/30![United Airlines logo]()
$489
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/149:45 am -
1 stop4h 13m
Wed 11/188:15 am -
1 stop4h 58m
Deal found 10/30![United Airlines logo]()
$439
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/171:56 pm -
1 stop5h 01m
Thu 1/76:20 am -
1 stop7h 00m
Deal found 11/1![United Airlines logo]()
$424
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:45 am -
2 stops7h 13m
Sat 11/216:15 am -
2 stops9h 37m
Deal found 11/2![United Airlines logo]()
$449
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/285:45 am -
1 stop4h 00m
Sat 12/52:50 pm -
1 stop4h 57m
Deal found 10/29![United Airlines logo]()
$319
One-way flights from Knoxville to HarrisburgSearch for one-way flight options from Knoxville to Harrisburg. Find affordable one-way fares based on user searches. Data last updated November 3, 2026.
Search for one-way flight options from Knoxville to Harrisburg. Find affordable one-way fares based on user searches. Data last updated November 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/138:35 am -
1 stop27h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/30![Allegiant Air logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:20 am -
2 stops28h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/30![Multiple Airlines logo]()
$316
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:01 am -
1 stop4h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![American Airlines logo]()
$350
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/101:56 pm -
2 stops9h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![United Airlines logo]()
$355
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:08 pm -
3 stops47h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Allegiant Air logo]()
$517
Find flight deals from Knoxville to Harrisburg
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Harrisburg (MDT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 3, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $319 (United Airlines) |
One-way from | $250 (Kiwi.com) |
Popular in | May |
Cheapest in | December |
Average price | $541 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Harrisburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 3, 2026.
Use the filters below to find and compare flights from Knoxville to Harrisburg that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleHarrisburg
TYS Knoxville McGhee Tyson - MDT Harrisburg
TYSMDT
Knoxville McGhee Tyson
Fri 11/13
8:35 am-11:45 am
1 stop27h 10m
Harrisburg
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$250
KnoxvilleHarrisburg
TYS Knoxville McGhee Tyson - MDT Harrisburg
TYSMDT
Knoxville McGhee Tyson
Fri 11/13
7:20 am-11:45 am
2 stops28h 25m
Harrisburg
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$316
KnoxvilleHarrisburg
TYS Knoxville McGhee Tyson - MDT Harrisburg
TYSMDT
Knoxville McGhee Tyson
Sat 11/28
5:45 am-9:45 am
1 stop4h 00m
Harrisburg
Sat 12/5
2:50 pm-7:47 pm
1 stop4h 57m
$319
Quickest round-trip
KnoxvilleHarrisburg
TYS Knoxville McGhee Tyson - MDT Harrisburg
TYSMDT
Knoxville McGhee Tyson
Tue 11/10
6:01 am-10:20 am
1 stop4h 19m
Harrisburg
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$350
KnoxvilleHarrisburg
TYS Knoxville McGhee Tyson - MDT Harrisburg
TYSMDT
Knoxville McGhee Tyson
Tue 11/10
1:56 pm-11:44 pm
2 stops9h 48m
Harrisburg
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$355
KnoxvilleHarrisburg
TYS Knoxville McGhee Tyson - MDT Harrisburg
TYSMDT
Knoxville McGhee Tyson
Thu 1/7
9:45 am-1:56 pm
1 stop4h 11m
Harrisburg
Mon 1/11
8:35 am-4:54 pm
1 stop8h 19m
$409
KnoxvilleHarrisburg
TYS Knoxville McGhee Tyson - MDT Harrisburg
TYSMDT
Knoxville McGhee Tyson
Tue 11/17
6:45 am-1:58 pm
2 stops7h 13m
Harrisburg
Thu 1/7
6:20 am-1:20 pm
2 stops7h 00m
$434
KnoxvilleHarrisburg
TYS Knoxville McGhee Tyson - MDT Harrisburg
TYSMDT
Knoxville McGhee Tyson
Sat 11/14
6:45 am-1:58 pm
2 stops7h 13m
Harrisburg
Wed 11/18
8:15 am-1:13 pm
1 stop4h 58m
$444
KnoxvilleHarrisburg
TYS Knoxville McGhee Tyson - MDT Harrisburg
TYSMDT
Knoxville McGhee Tyson
Tue 11/17
6:45 am-1:58 pm
2 stops7h 13m
Harrisburg
Sat 11/21
6:15 am-3:52 pm
2 stops9h 37m
$449
KnoxvilleHarrisburg
TYS Knoxville McGhee Tyson - MDT Harrisburg
TYSMDT
Knoxville McGhee Tyson
Tue 11/10
6:08 pm-5:55 pm
3 stops47h 47m
Harrisburg
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$517
Sorted by cheapest first
Compare providers for flights from Knoxville to Harrisburg
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Harrisburg in November.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-Harrisburg flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Harrisburg flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Harrisburg flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-Harrisburg flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Harrisburg flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to Harrisburg
Have a flexible travel schedule? Discover the best time to fly to Harrisburg from Knoxville with our price prediction graph.
TYS-MDT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Harrisburg
Reviews of airlines servicing Harrisburg
Get insights into the airlines that provide service to Harrisburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Harrisburg. Reviews last updated November 3, 2026.
Read reviews from past customers who have flown United Airlines and American Airlines from Knoxville to Harrisburg. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.7
Overall
7.3
Crew
8.1
Entertainment
7.1
Comfort
7.3
Food
6.7
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Boarding
7.7
Overall
7.3
Crew
8.1
Entertainment
7.1
Comfort
7.3
Food
6.7
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Boarding
7.7
Overall
7.3
Crew
8.1
Entertainment
7.1
Comfort
7.3
Food
6.7
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Harrisburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Harrisburg?
Book flights to Harrisburg if you plan to visit one of these locationsHershey
Mechanicsburg
Camp Hill
Carlisle
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Knoxville and Harrisburg flights
Browse other Knoxville and Harrisburg flight options. Last updated on November 3, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on November 3, 2026.
Popular flight searches
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Top 2 airlines flying from Knoxville to Harrisburg
Discover the top 2 airlines that operate flights from Knoxville to Harrisburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$309 | Average$489 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$378 | Average$606 | FlexibilityNo cancel fee | On-time71% |