HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Harrisburg

$267+ Cheap flights from Knoxville to Harrisburg (TYS - MDT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/9. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MDT
Aug 28 — Sep 41
Fri 8/28
Fri 9/4
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Knoxville to Harrisburg with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Knoxville to Harrisburg

Cheapest flights from Knoxville to Harrisburg
Explore the most affordable flight options available from Knoxville to Harrisburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2026.

This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:12 pm
TYS
-
MDT
1 stop5h 31m
Delta
Mon 8/316:24 pm
MDT
-
TYS
1 stop5h 28m
Delta
Deal found 7/26$299
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1911:43 am
TYS
-
MDT
1 stop4h 35m
Delta
Sat 11/2812:09 pm
MDT
-
TYS
1 stop5h 50m
Delta
Deal found 7/29$334
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/95:00 am
TYS
-
MDT
1 stop6h 46m
American Airlines
Sat 8/154:49 pm
MDT
-
TYS
1 stop4h 09m
American Airlines
Deal found 7/28$349
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/195:45 am
TYS
-
MDT
1 stop4h 00m
United Airlines
Sun 11/226:15 am
MDT
-
TYS
1 stop4h 35m
United Airlines
Deal found 7/24$369
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/258:05 pm
TYS
-
MDT
1 stop4h 20m
American Airlines
Tue 7/282:25 pm
MDT
-
TYS
1 stop5h 35m
American Airlines
Deal found 7/25$389
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:00 am
TYS
-
MDT
2 stops7h 50m
United Airlines
Sun 8/26:15 am
MDT
-
TYS
1 stop4h 27m
United Airlines
Deal found 7/25$394
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/127:00 am
TYS
-
MDT
1 stop6h 32m
United Airlines
Sun 8/167:59 pm
MDT
-
TYS
1 stop4h 00m
United Airlines
Deal found 7/28$399
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:45 am
TYS
-
MDT
1 stop4h 00m
United Airlines
Sun 11/226:15 am
MDT
-
TYS
2 stops10h 42m
United Airlines
Deal found 7/28$421
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:00 am
TYS
-
MDT
2 stops7h 59m
United Airlines
Tue 10/202:00 pm
MDT
-
TYS
1 stop6h 49m
United Airlines
Deal found 7/26$427
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/19:45 am
TYS
-
MDT
1 stop4h 18m
United Airlines
Wed 9/27:59 pm
MDT
-
TYS
1 stop4h 00m
United Airlines
Deal found 7/27$457

Find flight deals from Knoxville to Harrisburg

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Harrisburg (MDT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$299
(Delta)

One-way from

$267
(Kiwi.com)

Popular in

May

Cheapest in

July

Average price

$308
Provider with most accurate pricing for Knoxville McGhee Tyson-Harrisburg flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Harrisburg flights.
Search Deals
From Knoxville McGhee Tyson to Harrisburg
Search Deals
One-way flight from Knoxville McGhee Tyson to Harrisburg
Search Deals
Highest demand for flights based on searches. 27% potential increase in price ($204 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($39 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Harrisburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2026.
Use the filters below to find and compare flights from Knoxville to Harrisburg that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Fri 8/28

6:12 pm-11:43 pm

1 stop5h 31m

Harrisburg

Mon 8/31

6:24 pm-11:52 pm

1 stop5h 28m

$299

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Wed 8/12

7:00 am-2:03 pm

2 stops7h 03m

Harrisburg

Sun 8/16

6:37 am-10:37 am

1 stop4h 00m

$404
Quickest round-trip

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Tue 9/1

9:45 am-2:03 pm

1 stop4h 18m

Harrisburg

Wed 9/2

7:59 pm-11:59 pm

1 stop4h 00m

$457

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Sun 8/9

3:56 pm-9:00 am

1 stop17h 04m

Harrisburg

Mon 8/10

5:52 pm-12:06 pm

2 stops42h 14m

$498

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Sun 8/9

7:45 am-5:08 pm

1 stop9h 23m

Harrisburg

Mon 8/10

9:50 am-10:44 pm

1 stop12h 54m

$583

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Sun 8/9

6:00 am-1:50 pm

2 stops7h 50m

Harrisburg

Mon 8/10

6:15 am-5:00 pm

2 stops10h 45m

$933
Cheapest one-way
Quickest one-way

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Sun 8/9

3:56 pm-9:00 am

1 stop17h 04m

$267

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Sun 8/9

7:45 am-5:02 pm

2 stops33h 17m

$335

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/28

Sorted by cheapest first

Compare providers for flights from Knoxville to Harrisburg

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Harrisburg in July.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Harrisburg flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Harrisburg flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Harrisburg flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Harrisburg flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Harrisburg flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Harrisburg

Have a flexible travel schedule? Discover the best time to fly to Harrisburg from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Harrisburg

What is the cheapest month to book a flight from Knoxville to Harrisburg?

Currently, July is the cheapest month in which you can book a flight from Knoxville to Harrisburg (average of $308). Flying from Knoxville to Harrisburg in May is currently the most expensive (average of $972). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Harrisburg

Get insights into the airlines that provide service to Harrisburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Harrisburg. Reviews last updated July 29, 2026.
Read reviews from past customers who have flown United Airlines and American Airlines from Knoxville to Harrisburg. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
10,052 reviews

Comfort

7.3

Crew

8.1

Overall

7.4

Entertainment

7.1

Food

6.6

Boarding

7.7

Reviews

1 / 20
6.0
Good

ROHIT,Jun 2026

IND - EWR

It should not be delayed by 2 hours. I missed the important event due to this
United Airlines
7.4
Good
10,052 reviews
United Airlines
7.4
Good
10,052 reviews

Comfort

7.3

Crew

8.1

Overall

7.4

Entertainment

7.1

Food

6.6

Boarding

7.7

Reviews

1 / 20
6.0
Good

ROHIT,Jun 2026

IND - EWR

It should not be delayed by 2 hours. I missed the important event due to this
American Airlines
7.1
Good
11,839 reviews
United Airlines
7.4
Good
10,052 reviews

Comfort

7.3

Crew

8.1

Overall

7.4

Entertainment

7.1

Food

6.6

Boarding

7.7

Reviews

1 / 20
6.0
Good

ROHIT,Jun 2026

IND - EWR

It should not be delayed by 2 hours. I missed the important event due to this

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Harrisburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Harrisburg?

    A quick flight from Knoxville to Harrisburg can take about 5h 31m. Delta provides one of the quickest options available for as low as $299. The distance between Knoxville and Harrisburg is about 496 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Knoxville to Harrisburg round-trip?

    American Airlines, at $228, was found to be the cheapest airline from Knoxville to Harrisburg. An alternate airline flying to your destination would be United Airlines. American Airlines is 58% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Knoxville to Harrisburg that include hotel bookings?

    Yes. In addition to deals on Knoxville to Harrisburg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Harrisburg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Harrisburg.

  • Can I find deals for business class flights from Knoxville to Harrisburg?

    Yes. Cheapflights offers flight deals from Knoxville to Harrisburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Harrisburg?

    Currently, July is the cheapest month in which you can book a flight from Knoxville to Harrisburg (average of $308). Flying from Knoxville to Harrisburg in May is currently the most expensive (average of $972). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Harrisburg?

Book flights to Harrisburg if you plan to visit one of these locations
Hershey
Mechanicsburg
Camp Hill
Carlisle

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Knoxville to Harrisburg

See prices for flight routes from nearby airports that may be better suited for you.
Nashville to LaGuardia flights
Nashville to John F Kennedy Intl flights
Nashville to Newark flights
Memphis to LaGuardia flights
Memphis to Newark flights
Memphis to John F Kennedy Intl flights
Nashville to Philadelphia flights
Knoxville to LaGuardia flights
Nashville to Reagan-National flights
Chattanooga to LaGuardia flights
Knoxville to John F Kennedy Intl flights
Chattanooga to Newark flights
Chattanooga to John F Kennedy Intl flights
Nashville to Dulles Intl flights
Memphis to Reagan-National flights
Knoxville to Newark flights
Memphis to Dulles Intl flights
Knoxville to Reagan-National flights
Memphis to Philadelphia flights
Memphis to Harrisburg flights
Knoxville to Dulles Intl flights
Nashville to Pittsburgh flights
Chattanooga to Dulles Intl flights
Memphis to Pittsburgh flights
Chattanooga to Reagan-National flights
Blountville to Newark flights
Nashville to Harrisburg flights
Knoxville to Pittsburgh flights
Chattanooga to Philadelphia flights
Blountville to LaGuardia flights
Knoxville to Philadelphia flights
Nashville to Allentown flights
Knoxville to State College flights
Chattanooga to Harrisburg flights
Blountville to Philadelphia flights
Chattanooga to Pittsburgh flights
Nashville to Scranton flights
Knoxville to Allentown flights
Nashville to State College flights
Chattanooga to Elmira flights
Memphis to Allentown flights
Chattanooga to Allentown flights
Knoxville to Elmira flights
Nashville to Elmira flights
Blountville to Reagan-National flights

Top 2 airlines flying from Knoxville to Harrisburg

Discover the top 2 airlines that operate flights from Knoxville to Harrisburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$228Average$496FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$309Average$505FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.
Site
©2026 Cheapflights