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$164+ Cheap flights from Knoxville to Harrisburg (TYS - MDT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/8. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MDT
Jun 22 — Jun 291
Mon 6/22
Mon 6/29
1 adult, Economy
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Cheap flight deals from Knoxville to Harrisburg

Cheapest flights from Knoxville to Harrisburg
Explore the most affordable flight options available from Knoxville to Harrisburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 23, 2026.

This Delta deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/207:15 am
TYS
-
MDT
1 stop4h 27m
Delta
Sat 6/275:34 pm
MDT
-
TYS
1 stop4h 07m
Delta
Deal found 5/21$289
This American Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:12 am
TYS
-
MDT
1 stop3h 56m
American Airlines
Mon 6/87:08 pm
MDT
-
TYS
1 stop4h 45m
American Airlines
Deal found 5/20$339
This Kiwi.com deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2210:03 pm
TYS
-
MDT
1 stop13h 26m
Allegiant Air
Thu 6/258:50 pm
MDT
-
TYS
1 stop24h 23m
Allegiant Air
Deal found 5/22$341
This American Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/215:00 am
TYS
-
MDT
1 stop4h 28m
American Airlines
Thu 5/282:20 pm
MDT
-
TYS
1 stop5h 50m
American Airlines
Deal found 5/20$369
This United Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:19 pm
TYS
-
MDT
1 stop4h 11m
United Airlines
Sun 6/146:15 am
MDT
-
TYS
1 stop4h 27m
United Airlines
Deal found 5/20$374
This Delta deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:35 pm
TYS
-
MDT
1 stop6h 16m
Delta
Sun 5/246:00 am
MDT
-
TYS
1 stop5h 09m
Delta
Deal found 5/22$378
This United Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/225:41 pm
TYS
-
MDT
1 stop6h 46m
United Airlines
Mon 5/257:59 pm
MDT
-
TYS
1 stop3h 55m
United Airlines
Deal found 5/19$379
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/147:01 pm
TYS
-
MDT
1 stop14h 22m
Allegiant Air
Sat 6/2010:26 am
MDT
-
TYS
1 stop12h 29m
Allegiant Air
Deal found 5/20$388
This Kiwi.com deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/209:00 am
TYS
-
MDT
1 stop23h 50m
Allegiant Air
Sat 6/277:58 pm
MDT
-
TYS
2 stops40h 48m
Allegiant Air
Deal found 5/21$392
This United Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/175:45 am
TYS
-
MDT
1 stop3h 55m
United Airlines
Tue 6/237:59 pm
MDT
-
TYS
1 stop3h 55m
United Airlines
Deal found 5/18$403
This United Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:19 pm
TYS
-
MDT
1 stop4h 11m
United Airlines
Tue 6/97:59 pm
MDT
-
TYS
1 stop3h 55m
United Airlines
Deal found 5/21$419

Find flight deals from Knoxville to Harrisburg

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Harrisburg (MDT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 23, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$289
(Delta)

One-way from

$164
(Kiwi.com)

Popular in

August

Cheapest in

December

Average price

$353
Provider with most accurate pricing for Knoxville McGhee Tyson-Harrisburg flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Harrisburg flights.
Search Deals
From Knoxville McGhee Tyson to Harrisburg
Search Deals
One-way flight from Knoxville McGhee Tyson to Harrisburg
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($33 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($17 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Harrisburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 23, 2026.
Use the filters below to find and compare flights from Knoxville to Harrisburg that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Mon 6/22

10:03 pm-11:29 am

1 stop13h 26m

Harrisburg

Thu 6/25

8:50 pm-9:13 pm

1 stop24h 23m

$341

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Fri 6/5

7:19 pm-11:30 pm

1 stop4h 11m

Harrisburg

Sun 6/14

6:15 am-10:42 am

1 stop4h 27m

$374
Quickest round-trip

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Wed 6/17

5:45 am-9:40 am

1 stop3h 55m

Harrisburg

Tue 6/23

7:59 pm-11:54 pm

1 stop3h 55m

$403

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Fri 6/5

7:19 pm-11:30 pm

1 stop4h 11m

Harrisburg

Tue 6/9

7:59 pm-11:54 pm

1 stop3h 55m

$419

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Fri 6/5

5:59 pm-11:51 pm

1 stop5h 52m

Harrisburg

Sun 6/7

6:04 am-11:09 am

1 stop5h 05m

$429

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Sat 8/15

7:00 am-1:30 pm

1 stop6h 30m

Harrisburg

Wed 8/19

7:59 pm-11:59 pm

1 stop4h 00m

$447

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Thu 8/20

5:45 am-9:37 am

1 stop3h 52m

Harrisburg

Mon 8/24

10:45 am-8:53 pm

2 stops10h 08m

$452
Cheapest one-way

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Thu 10/8

7:36 pm-3:18 pm

1 stop19h 42m

$164

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Wed 7/1

7:15 am-11:42 am

1 stop4h 27m

$184

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Fri 6/12

9:17 pm-5:29 pm

1 stop20h 12m

$189

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/21

Showing 1-10 of 13 resultsSorted by cheapest first
1
2

Compare providers for flights from Knoxville to Harrisburg

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Harrisburg in May.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Harrisburg flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Harrisburg flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Harrisburg flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Harrisburg flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Harrisburg flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Harrisburg

Have a flexible travel schedule? Discover the best time to fly to Harrisburg from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Harrisburg

What is the cheapest month to book a flight from Knoxville to Harrisburg?

Currently, December is the cheapest month in which you can book a flight from Knoxville to Harrisburg (average of $321). Flying from Knoxville to Harrisburg in August is currently the most expensive (average of $674). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Knoxville to Harrisburg?

Reviews of airlines servicing Harrisburg

Get insights into the airlines that provide service to Harrisburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Harrisburg. Reviews last updated May 23, 2026.
Read reviews from past customers who have flown United Airlines and American Airlines from Knoxville to Harrisburg. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,751 reviews

Entertainment

7.1

Comfort

7.3

Boarding

7.7

Overall

7.4

Crew

8.1

Food

6.6

Reviews

1 / 20
4.0
Okay

Dynasty,May 2026

LAX - EWR

The food wasn’t nice - Hosts were not that kind.
United Airlines
7.4
Good
9,751 reviews
United Airlines
7.4
Good
9,751 reviews

Entertainment

7.1

Comfort

7.3

Boarding

7.7

Overall

7.4

Crew

8.1

Food

6.6

Reviews

1 / 20
4.0
Okay

Dynasty,May 2026

LAX - EWR

The food wasn’t nice - Hosts were not that kind.
American Airlines
7.1
Good
11,642 reviews
United Airlines
7.4
Good
9,751 reviews

Entertainment

7.1

Comfort

7.3

Boarding

7.7

Overall

7.4

Crew

8.1

Food

6.6

Reviews

1 / 20
4.0
Okay

Dynasty,May 2026

LAX - EWR

The food wasn’t nice - Hosts were not that kind.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Harrisburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Harrisburg?

    A quick flight from Knoxville to Harrisburg can take about 4h 11m. Allegiant Air provides one of the quickest options available for as low as $374. The distance between Knoxville and Harrisburg is about 496 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Knoxville to Harrisburg round-trip?

    American Airlines, at $228, was found to be the cheapest airline from Knoxville to Harrisburg. An alternate airline flying to your destination would be United Airlines. American Airlines is 52% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Knoxville to Harrisburg that include hotel bookings?

    Yes. In addition to deals on Knoxville to Harrisburg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Harrisburg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Harrisburg.

  • Can I find deals for business class flights from Knoxville to Harrisburg?

    Yes. Cheapflights offers flight deals from Knoxville to Harrisburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Harrisburg?

    Currently, December is the cheapest month in which you can book a flight from Knoxville to Harrisburg (average of $321). Flying from Knoxville to Harrisburg in August is currently the most expensive (average of $674). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Harrisburg?

Book flights to Harrisburg if you plan to visit one of these locations
Mechanicsburg
Hershey
Camp Hill
Carlisle

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Top 2 airlines flying from Knoxville to Harrisburg

Discover the top 2 airlines that operate flights from Knoxville to Harrisburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 23, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$228Average$466FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$308Average$500FlexibilityNo cancel feeOn-time69%

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