How long is the flight from Knoxville to Harrisburg?

A quick flight from Knoxville to Harrisburg can take about 7h 06m. United Airlines provides one of the quickest options available for as low as $259. The distance between Knoxville and Harrisburg is about 496 mi.

What are the cheapest airlines flying from Knoxville to Harrisburg round-trip?

American Airlines, at $228, was found to be the cheapest airline from Knoxville to Harrisburg.Alternate airlines to your destination round-trip include Delta and United Airlines. American Airlines is 50% cheaper than the average price of flights available within the next 90 days to this destination.

In terms of precipitation, rainfall in Harrisburg ranges from 2.7 - 4.1 inches per month. May is typically the wettest month, when rainfall can reach 4.1 in. February is typically the driest time to visit Harrisburg when rainfall is around 2.7 in.

If weather is an important factor for your trip to Harrisburg, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 30.2 F).

What are the most popular airlines that fly from Knoxville to Harrisburg?

The most popular airlines flying from Knoxville to Harrisburg are American Airlines, United Airlines and Delta. Something to consider prior to booking your flight.

What is the cheapest time of day to fly from TYS to MDT?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Knoxville to Harrisburg as you normally would.

Most accurate provider : When it comes to deals on Knoxville-Harrisburg flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Knoxville-Harrisburg flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Knoxville-Harrisburg flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Knoxville-Harrisburg flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Harrisburg flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Knoxville to Harrisburg that include hotel bookings?

Yes. In addition to deals on Knoxville to Harrisburg flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Knoxville to Harrisburg?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Harrisburg.

Can I find deals for business class flights from Knoxville to Harrisburg?

Yes. Cheapflights offers flight deals from Knoxville to Harrisburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$209+ Flights from Knoxville to Harrisburg

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Cheap flight deals from Knoxville to Harrisburg

Cheapest flights from Knoxville to Harrisburg
Explore the most affordable flight options available from Knoxville to Harrisburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 31, 2025.

Wed 12/312:00 pmTYS - MDT

1 stop4h 58mUnited Airlines

Sat 1/36:15 amMDT - TYS

1 stop4h 41mUnited Airlines

Deal found 12/31

$464

Best flights from Knoxville to Harrisburg
Discover carefully curated flight deals from Knoxville to Harrisburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 31, 2025.

Thu 1/156:45 amTYS - MDT

2 stops7h 06mUnited Airlines

Sun 1/253:10 pmMDT - TYS

1 stop5h 42mUnited Airlines

Deal found 12/30

$259

Thu 1/221:59 pmTYS - MDT

1 stop7h 06mUnited Airlines

Mon 1/263:10 pmMDT - TYS

1 stop5h 42mUnited Airlines

Deal found 12/28

$309

Thu 1/156:45 amTYS - MDT

1 stop7h 30mUnited Airlines

Sat 1/173:10 pmMDT - TYS

1 stop5h 42mUnited Airlines

Deal found 12/29

$319

Wed 1/1411:10 amTYS - MDT

1 stop5h 24mUnited Airlines

Sun 1/186:15 amMDT - TYS

1 stop4h 42mUnited Airlines

Deal found 12/29

$319

Thu 1/159:30 amTYS - MDT

1 stop4h 21mUnited Airlines

Sun 1/186:15 amMDT - TYS

1 stop4h 42mUnited Airlines

Deal found 12/29

$319

Last-minute flights from Knoxville to Harrisburg
Discover last-minute flight deals from Knoxville to Harrisburg. Data last updated December 31, 2025 and is based on user searches.

Wed 12/312:00 pmTYS - MDT

1 stop4h 58mUnited Airlines

Sat 1/36:15 amMDT - TYS

1 stop4h 41mUnited Airlines

Deal found 12/31

$464

Wed 1/1411:10 amTYS - MDT

2 stops7h 49mUnited Airlines

Sun 1/186:15 amMDT - TYS

1 stop4h 42mUnited Airlines

Deal found 12/29

$398

Thu 1/159:30 amTYS - MDT

1 stop4h 21mUnited Airlines

Sun 1/2510:34 amMDT - TYS

1 stop4h 15mUnited Airlines

Deal found 12/30

$254

Thu 1/159:30 amTYS - MDT

1 stop4h 21mUnited Airlines

Sun 1/186:15 amMDT - TYS

1 stop4h 42mUnited Airlines

Deal found 12/29

$319

Thu 1/156:45 amTYS - MDT

2 stops7h 06mUnited Airlines

Sat 1/1710:34 amMDT - TYS

2 stops10h 18mUnited Airlines

Deal found 12/29

$403

Thu 1/221:59 pmTYS - MDT

1 stop7h 06mUnited Airlines

Mon 1/263:10 pmMDT - TYS

1 stop5h 42mUnited Airlines

Deal found 12/28

$309

One-way flights from Knoxville to Harrisburg
Search for one-way flight options from Knoxville to Harrisburg. Find affordable one-way fares based on user searches. Data last updated December 31, 2025.

Wed 1/146:10 pmTYS - MDT

1 stop5h 16mDelta

Deal found 12/31

$209

Wed 1/147:41 amTYS - MDT

2 stops6h 57mAmerican Airlines

Deal found 12/31

$214

Thu 1/157:26 pmTYS - MDT

3 stops42h 10mMultiple Airlines

Deal found 12/31

$239

Wed 1/144:47 pmTYS - MDT

3 stops48h 26mAllegiant Air

Deal found 12/30

$257

Thu 1/156:45 amTYS - MDT

1 stop7h 30mUnited Airlines

Deal found 12/29

$329

Find flight deals from Knoxville to Harrisburg

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$254 (United Airlines)
One-way from	$209 (Delta)
Popular in	January
Cheapest in	March
Average price	$321

Provider with most accurate pricing for Knoxville McGhee Tyson-Harrisburg flight deals.

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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Harrisburg flights.

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From Knoxville McGhee Tyson to Harrisburg

Search Deals

One-way flight from Knoxville McGhee Tyson to Harrisburg

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High demand for flights, 0% potential price rise

Search Deals

Cheapest flight prices on average. 4% potential price decrease ($21 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

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Cheapflights Fare Finder

Use the filters below to find and compare flights from Knoxville to Harrisburg that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Thu 1/15

6:45 am-1:51 pm

2 stops7h 06m

Harrisburg

Sun 1/25

3:10 pm-8:52 pm

1 stop5h 42m

$259

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Thu 1/22

1:59 pm-9:05 pm

1 stop7h 06m

Harrisburg

Mon 1/26

3:10 pm-8:52 pm

1 stop5h 42m

$309

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Thu 1/15

6:45 am-2:15 pm

1 stop7h 30m

Harrisburg

Sat 1/17

3:10 pm-8:52 pm

1 stop5h 42m

$319

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Wed 1/14

11:10 am-4:34 pm

1 stop5h 24m

Harrisburg

Sun 1/18

6:15 am-10:57 am

1 stop4h 42m

$319

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Thu 1/15

9:30 am-1:51 pm

1 stop4h 21m

Harrisburg

Sun 1/18

6:15 am-10:57 am

1 stop4h 42m

$319

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Wed 1/14

7:41 am-12:03 pm

1 stop4h 22m

$209

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Thu 1/15

11:05 am-5:07 pm

1 stop6h 02m

$209

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Wed 1/14

6:10 pm-11:26 pm

1 stop5h 16m

$209

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Thu 1/15

6:45 am-1:51 pm

2 stops7h 06m

$214

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

Thu 1/15

7:26 pm-1:36 pm

3 stops42h 10m

$239

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/30

Showing 1-10 of 11 results

Compare providers for flights from Knoxville to Harrisburg

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Harrisburg in December.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Knoxville-Harrisburg flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Knoxville-Harrisburg flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Knoxville-Harrisburg flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Knoxville-Harrisburg flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Harrisburg flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Harrisburg

Have a flexible travel schedule? Discover the best time to fly to Harrisburg from Knoxville with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Harrisburg

What is the cheapest month to book a flight from Knoxville to Harrisburg?

Currently, August is the cheapest month in which you can book a flight from Knoxville to Harrisburg (average of $125). Flying from Knoxville to Harrisburg in December is currently the most expensive (average of $230). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Harrisburg

Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Knoxville to Harrisburg. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

7.9

Good

8,013 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Delta

7.9

Good

8,013 reviews

Delta

7.9

Good

8,013 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

United Airlines

7.4

Good

9,129 reviews

Delta

7.9

Good

8,013 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

American Airlines

7.2

Good

11,069 reviews

Delta

7.9

Good

8,013 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

Related info for your journey

How long is the flight from Knoxville to Harrisburg?
A quick flight from Knoxville to Harrisburg can take about 7h 06m. United Airlines provides one of the quickest options available for as low as $259. The distance between Knoxville and Harrisburg is about 496 mi.
What are the cheapest airlines flying from Knoxville to Harrisburg round-trip?
American Airlines, at $228, was found to be the cheapest airline from Knoxville to Harrisburg.Alternate airlines to your destination round-trip include Delta and United Airlines. American Airlines is 50% cheaper than the average price of flights available within the next 90 days to this destination.
Can I find deals for flights from Knoxville to Harrisburg that include hotel bookings?
Yes. In addition to deals on Knoxville to Harrisburg flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Knoxville to Harrisburg?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Harrisburg.
Can I find deals for business class flights from Knoxville to Harrisburg?
Yes. Cheapflights offers flight deals from Knoxville to Harrisburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Knoxville to Harrisburg?
Currently, August is the cheapest month in which you can book a flight from Knoxville to Harrisburg (average of $125). Flying from Knoxville to Harrisburg in December is currently the most expensive (average of $230). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Knoxville to Harrisburg

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$228	Average$353	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$233	Average$353	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$321	Average$562	FlexibilityNo cancel fee	On-time69%

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$209+ Cheap flights from Knoxville to Harrisburg (TYS - MDT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/14. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Knoxville to Harrisburg with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Knoxville to Harrisburg

Cheapest flights from Knoxville to HarrisburgExplore the most affordable flight options available from Knoxville to Harrisburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 31, 2025.

Explore the most affordable flight options available from Knoxville to Harrisburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 31, 2025.

Find flight deals from Knoxville to Harrisburg

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Knoxville to Harrisburg that are best for you.

Compare providers for flights from Knoxville to Harrisburg

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Harrisburg in December.

Best time to book a flight from Knoxville to Harrisburg

Have a flexible travel schedule? Discover the best time to fly to Harrisburg from Knoxville with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Harrisburg

What is the cheapest month to book a flight from Knoxville to Harrisburg?

Reviews of airlines servicing Harrisburg

Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Knoxville to Harrisburg. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Harrisburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Knoxville to Harrisburg?

What are the cheapest airlines flying from Knoxville to Harrisburg round-trip?

Can I find deals for flights from Knoxville to Harrisburg that include hotel bookings?

How can I find direct flights from Knoxville to Harrisburg?

Can I find deals for business class flights from Knoxville to Harrisburg?

What is the cheapest month to book a flight from Knoxville to Harrisburg?

Traveling to a place near Harrisburg?

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Alternative routes for Knoxville to Harrisburg

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Top 3 airlines flying from Knoxville to Harrisburg

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Cheapest flights from Knoxville to Harrisburg
Explore the most affordable flight options available from Knoxville to Harrisburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 31, 2025.