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$130+ Cheap flights from Knoxville to Harrisburg (TYS - MDT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/3. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MDT
ago. 25 — sep. 11
lun. 8/25
lun. 9/1
1 adult, Economy
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Cheap flight deals from Knoxville to Harrisburg

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Harrisburg (MDT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated agosto 20, 2025.

Round-trip from

$229
(American Airlines)

One-way from

$130
(Kiwi.com)

Popular in

January

Cheapest in

March

Average price

$448
From Knoxville McGhee Tyson to Harrisburg
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One-way flight from Knoxville McGhee Tyson to Harrisburg
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High demand for flights, 0% potential price rise
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Cheapest flight prices on average. 3% potential price decrease ($14 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Knoxville to Harrisburg

Cheapest flights from Knoxville to Harrisburg
Explore the most affordable flight options available from Knoxville to Harrisburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on agosto 20, 2025.

This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/257:48 amTYS - MDT
1 stop6h 41mAmerican Airlines
jue. 1/15:00 amMDT - TYS
1 stop5h 16mAmerican Airlines
Deal found 8/18$229
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/207:18 amTYS - MDT
1 stop4h 37mAmerican Airlines
lun. 9/224:45 pmMDT - TYS
1 stop6h 18mAmerican Airlines
Deal found 8/18$283
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/186:10 pmTYS - MDT
1 stop4h 00mAmerican Airlines
sáb. 9/204:45 pmMDT - TYS
1 stop6h 18mAmerican Airlines
Deal found 8/17$289
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/207:00 amTYS - MDT
2 stops6h 48mUnited Airlines
lun. 9/225:48 pmMDT - TYS
1 stop4h 57mUnited Airlines
Deal found 8/18$294
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/42:00 pmTYS - MDT
1 stop5h 52mUnited Airlines
lun. 9/86:15 amMDT - TYS
1 stop4h 13mUnited Airlines
Deal found 8/20$299
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/29:55 amTYS - MDT
1 stop3h 53mUnited Airlines
sáb. 9/62:24 pmMDT - TYS
2 stops8h 21mUnited Airlines
Deal found 8/18$304
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/289:35 amTYS - MDT
1 stop3h 38mAmerican Airlines
mar. 9/212:50 pmMDT - TYS
1 stop4h 57mAmerican Airlines
Deal found 8/18$309
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 8/306:58 pmTYS - MDT
1 stop16h 22mAllegiant Air
lun. 9/19:13 pmMDT - TYS
1 stop22h 11mAllegiant Air
Deal found 8/18$316
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/266:26 pmTYS - MDT
1 stop3h 34mAmerican Airlines
jue. 1/12:01 pmMDT - TYS
1 stop3h 40mAmerican Airlines
Deal found 8/18$339
This United Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 9/37:00 amTYS - MDT
2 stops6h 48mUnited Airlines
dom. 9/76:15 amMDT - TYS
2 stops7h 10mUnited Airlines
Deal found 8/19$349
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/2912:45 pmTYS - MDT
2 stops46h 35mMultiple Airlines
lun. 9/19:13 pmMDT - TYS
1 stop22h 11mMultiple Airlines
Deal found 8/18$358

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Harrisburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 20, 2025.
Use the filters below to find and compare flights from Knoxville to Harrisburg that are best for you.

Fly from

Knoxville

Fly to

Harrisburg

Route

Depart

Return

Price

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

sáb. 9/20

7:18 am-11:55 am

1 stop4h 37m

Harrisburg

lun. 9/22

4:45 pm-11:03 pm

1 stop6h 18m

$283

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

vie. 9/19

6:10 pm-10:11 pm

1 stop4h 01m

Harrisburg

sáb. 9/20

6:30 pm-11:03 pm

1 stop4h 33m

$289

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

jue. 9/18

6:10 pm-10:10 pm

1 stop4h 00m

Harrisburg

sáb. 9/20

4:45 pm-11:03 pm

1 stop6h 18m

$289

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

sáb. 9/20

7:00 am-1:48 pm

2 stops6h 48m

Harrisburg

lun. 9/22

5:48 pm-10:45 pm

1 stop4h 57m

$294

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

jue. 9/4

5:05 am-10:13 am

1 stop5h 08m

Harrisburg

dom. 9/7

6:00 am-12:21 pm

1 stop6h 21m

$294

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

mié. 9/3

9:55 am-1:48 pm

1 stop3h 53m

Harrisburg

dom. 9/7

6:15 am-10:28 am

1 stop4h 13m

$299

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

jue. 9/4

2:00 pm-7:52 pm

1 stop5h 52m

Harrisburg

lun. 9/8

6:15 am-10:28 am

1 stop4h 13m

$299

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

mié. 9/3

4:55 pm-11:27 am

1 stop18h 32m

$130

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

sáb. 9/27

2:06 pm-9:31 am

1 stop19h 25m

$140

KnoxvilleHarrisburg

TYS - MDT

TYSMDT

Knoxville McGhee Tyson

mié. 10/22

9:55 am-1:54 pm

1 stop3h 59m

$228

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/19

Showing 1-10 of 14 results
1
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Best time to book a flight from Knoxville to Harrisburg

Have a flexible travel schedule? Discover the best time to fly to Harrisburg from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Harrisburg

What is the cheapest month to book a flight from Knoxville to Harrisburg?

Currently, January is the cheapest month in which you can book a flight from Knoxville to Harrisburg (average of $355). Flying from Knoxville to Harrisburg in November is currently the most expensive (average of $408). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to MDT?

Find hourly flight availability from Knoxville to Harrisburg. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated agosto 20, 2025.

Unlike in the evening, when flights are generally more expensive, you can save up to 24% on flights from Knoxville to Harrisburg by exploring options for tickets in the afternoon.

Reviews of airlines servicing Harrisburg

Get insights into the airlines that provide service to Harrisburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Harrisburg. Reviews last updated agosto 20, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Knoxville to Harrisburg. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,982 reviews

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,982 reviews
Delta
8.0
Very good
7,982 reviews

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,928 reviews
Delta
8.0
Very good
7,982 reviews

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,982 reviews

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Harrisburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Harrisburg?

    A quick flight from Knoxville to Harrisburg can take about 4h 37m. American Airlines provides one of the quickest options available for as low as $283. The distance between Knoxville and Harrisburg is about 496 mi.

  • What are the cheapest airlines flying from Knoxville to Harrisburg round-trip?

    American Airlines, at $228, was found to be the cheapest airline from Knoxville to Harrisburg.Alternate airlines to your destination round-trip include Delta and United Airlines. American Airlines is 44% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Knoxville to Harrisburg one-way?

    The cheapest airlines for a one-way flight from Knoxville to Harrisburg are Allegiant Air ($130), United Airlines ($228), and Delta ($233).

  • Can I find deals for flights from Knoxville to Harrisburg that include hotel bookings?

    Yes. In addition to deals on Knoxville to Harrisburg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Harrisburg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Harrisburg.

  • Can I find deals for business class flights from Knoxville to Harrisburg?

    Yes. Cheapflights offers flight deals from Knoxville to Harrisburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Harrisburg?

    Currently, January is the cheapest month in which you can book a flight from Knoxville to Harrisburg (average of $355). Flying from Knoxville to Harrisburg in November is currently the most expensive (average of $408). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Harrisburg?

Book flights to Harrisburg if you plan to visit one of these locations
Carlisle
Hershey
Mechanicsburg
Camp Hill

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Alternative routes for Knoxville to Harrisburg

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Top 3 airlines flying from Knoxville to Harrisburg

Discover the top 3 airlines that operate flights from Knoxville to Harrisburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$228Average$326FlexibilityNo cancel feeOn-time71%
DeltaCheapest$233Average$353FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$288Average$500FlexibilityNo cancel feeOn-time69%

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