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Guayaquil

$375+ Cheap flights from Missouri to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/26. Fares are subject to change and may not be available on all flights or dates of travel.
MCI — GYE
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheap flight deals from Missouri to Guayaquil

Cheapest flights from Missouri to Guayaquil
Explore the most affordable flight options available from Missouri to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This KAYAK deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/226:15 pmMCI - GYE
1 stop28h 38mSpirit Airlines
Wed 1/211:26 amGYE - MCI
1 stop10h 05mSpirit Airlines
Deal found 12/17$627
This KAYAK deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:15 pmMCI - GYE
1 stop28h 38mSpirit Airlines
Sat 12/2712:49 amGYE - MCI
2 stops23h 10mSpirit Airlines
Deal found 12/17$725
This KAYAK deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:15 pmMCI - GYE
1 stop28h 38mSpirit Airlines
Sat 1/312:49 amGYE - MCI
1 stop17h 21mSpirit Airlines
Deal found 12/16$809
This United Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/227:40 amMCI - GYE
2 stops15h 01mUnited Airlines
Thu 1/2212:20 pmGYE - MCI
2 stops22h 11mUnited Airlines
Deal found 12/17$947
This Mytrip deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:15 pmMCI - GYE
3 stops46h 30mMultiple Airlines
Sat 12/2712:49 amGYE - MCI
2 stops23h 10mMultiple Airlines
Deal found 12/17$953

Find flight deals from Missouri to Guayaquil

Keep the following information in mind while searching for Missouri to Guayaquil flight deals. Data was last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$379
(FlightHub)

One-way from

$375
(United Airlines)
Provider with most accurate pricing for Lambert-St Louis-Guayaquil Jose Joaquin de Olmedo flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Guayaquil Jose Joaquin de Olmedo flights.
Search Deals
From Missouri to Guayaquil Jose Joaquin de Olmedo
Search Deals
One-way flight from Missouri to Guayaquil Jose Joaquin de Olmedo
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Missouri to Guayaquil that are best for you.

Fly from

Missouri

Fly to

Guayaquil

Route

Depart

Return

Price

Kansas CityGuayaquil

MCI - GYE

MCIGYE

Kansas City

Thu 5/28

12:12 pm-11:01 pm

1 stop10h 49m

Guayaquil Jose Joaquin de Olmedo

Tue 6/2

11:59 pm-11:07 am

1 stop11h 08m

$379

Kansas CityGuayaquil

MCI - GYE

MCIGYE

Kansas City

Thu 5/28

11:12 am-10:40 pm

2 stops35h 28m

Guayaquil Jose Joaquin de Olmedo

Tue 6/2

11:59 pm-11:07 am

1 stop11h 08m

$515

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Fri 1/30

6:00 am-8:46 pm

2 stops13h 46m

Guayaquil Jose Joaquin de Olmedo

Fri 2/6

2:35 pm-9:22 am

2 stops43h 47m

$607

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Fri 1/30

6:02 pm-11:22 pm

1 stop28h 20m

Guayaquil Jose Joaquin de Olmedo

Fri 2/6

7:15 am-11:59 pm

1 stop17h 44m

$616

Kansas CityGuayaquil

MCI - GYE

MCIGYE

Kansas City

Mon 1/26

8:05 am-11:42 pm

2 stops14h 37m

Guayaquil Jose Joaquin de Olmedo

Wed 1/28

8:34 am-10:40 pm

2 stops15h 06m

$685

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Mon 2/2

6:00 am-11:42 pm

2 stops16h 42m

Guayaquil Jose Joaquin de Olmedo

Thu 2/5

8:34 am-9:22 am

2 stops25h 48m

$718

Kansas CityGuayaquil

MCI - GYE

MCIGYE

Kansas City

Sat 3/21

4:25 pm-5:33 pm

2 stops25h 08m

Guayaquil Jose Joaquin de Olmedo

Sat 3/28

12:20 pm-9:32 am

2 stops21h 12m

$743

Kansas CityGuayaquil

MCI - GYE

MCIGYE

Kansas City

Sat 3/21

5:00 am-1:30 pm

1 stop8h 30m

Guayaquil Jose Joaquin de Olmedo

Sat 3/28

2:30 pm-12:39 am

1 stop10h 09m

$760

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Fri 1/30

4:05 pm-11:35 pm

3 stops30h 30m

Guayaquil Jose Joaquin de Olmedo

Fri 2/6

3:35 pm-7:27 pm

3 stops28h 52m

$1,319

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Sun 4/26

10:09 am-5:31 pm

2 stops55h 22m

$375

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/17

Showing 1-10 of 15 results
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Best time to book a flight from Missouri to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Guayaquil
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Guayaquil from Missouri?

    Most people fly into Guayaquil Jose Joaquin de Olmedo (GYE) if they book a flight to Guayaquil from Missouri. Jose Joaquin de Olmedo is conveniently located just 2.5 mi from Guayaquil’s city center.

  • How long is the flight from Missouri to Guayaquil?

    A quick flight from Missouri to Guayaquil can take about 10h 49m. Spirit Airlines provides one of the quickest options available for as low as $379. Missouri and Guayaquil are separated by a distance of 3013 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Missouri to Guayaquil that include hotel bookings?

    Yes. In addition to deals on Missouri to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Guayaquil.

  • Can I find deals for business class flights from Missouri to Guayaquil?

    Yes. Cheapflights offers flight deals from Missouri to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Missouri to Guayaquil

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Missouri to Guayaquil

Discover the top airline that operate flights from Missouri to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$516Average$996FlexibilityNo cancel feeOn-time71%

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