$209+ Cheap flights from Missouri to Guayaquil (GYE)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/10. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GYE
Mar 16 — Mar 231
1 adult, Economy
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Find cheap flights from Missouri to Guayaquil with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Missouri to Guayaquil
Cheapest
Best
Last-minute
One-way
Cheapest flights from Missouri to GuayaquilExplore the most affordable flight options available from Missouri to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 14, 2026.
Explore the most affordable flight options available from Missouri to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 14, 2026.
This FlightHub deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/2112:24 pm
MCI
- GYE
1 stop10h 40m
Spirit Airlines
Sat 3/2811:59 pm
GYE
- MCI
1 stop11h 30m
Spirit Airlines
Deal found 2/10![Spirit Airlines logo]()
$334
This KAYAK deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2712:24 pm
MCI
- GYE
1 stop10h 40m
Spirit Airlines
Fri 4/1011:59 pm
GYE
- MCI
2 stops23h 54m
Spirit Airlines
Deal found 2/11![Spirit Airlines logo]()
$492
This KAYAK deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1112:15 pm
MCI
- GYE
1 stop10h 49m
Spirit Airlines
Wed 5/2711:59 pm
GYE
- MCI
1 stop11h 10m
Spirit Airlines
Deal found 2/10![Spirit Airlines logo]()
$531
This United Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/306:00 am
STL
- GYE
2 stops17h 39m
United Airlines
Mon 4/68:28 am
GYE
- STL
2 stops24h 57m
United Airlines
Deal found 2/13![United Airlines logo]()
$639
This American Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/305:15 am
STL
- GYE
1 stop8h 15m
American Airlines
Mon 4/62:30 pm
GYE
- STL
1 stop19h 46m
American Airlines
Deal found 2/13![American Airlines logo]()
$708
This United Airlines deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/286:00 am
STL
- GYE
2 stops13h 46m
United Airlines
Wed 3/412:20 pm
GYE
- STL
2 stops22h 01m
United Airlines
Deal found 2/12![United Airlines logo]()
$893
This LATAM Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2810:11 am
STL
- GYE
2 stops20h 37m
LATAM Airlines
Wed 3/42:25 pm
GYE
- STL
2 stops28h 17m
LATAM Airlines
Deal found 2/11![LATAM Airlines logo]()
$1,012
This Ovago deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1211:22 am
STL
- GYE
1 stop26h 08m
GOL
Sun 2/157:12 am
GYE
- STL
1 stop17h 44m
GOL
Deal found 2/11![GOL logo]()
$1,233
This Mytrip deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/304:05 pm
STL
- GYE
3 stops31h 25m
Multiple Airlines
Mon 4/66:50 pm
GYE
- STL
2 stops20h 34m
Multiple Airlines
Deal found 2/13![Multiple Airlines logo]()
$1,951
This Mytrip deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/127:41 am
STL
- GYE
3 stops29h 44m
Multiple Airlines
Sun 2/159:05 am
GYE
- STL
3 stops31h 24m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$2,512
Best flights from Missouri to GuayaquilDiscover carefully curated flight deals from Missouri to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 14, 2026.
Discover carefully curated flight deals from Missouri to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 14, 2026.
This FlightHub deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/2112:24 pm
MCI
- GYE
1 stop10h 40m
Spirit Airlines
Sat 3/2811:59 pm
GYE
- MCI
1 stop11h 30m
Spirit Airlines
Deal found 2/10![Spirit Airlines logo]()
$334
This United Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/306:00 am
STL
- GYE
2 stops17h 39m
United Airlines
Mon 4/68:28 am
GYE
- STL
2 stops24h 57m
United Airlines
Deal found 2/13![United Airlines logo]()
$639
This American Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/305:15 am
STL
- GYE
1 stop8h 15m
American Airlines
Mon 4/62:30 pm
GYE
- STL
1 stop19h 46m
American Airlines
Deal found 2/13![American Airlines logo]()
$708
This KAYAK deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2712:24 pm
MCI
- GYE
1 stop10h 40m
Spirit Airlines
Fri 4/1011:59 pm
GYE
- MCI
2 stops23h 54m
Spirit Airlines
Deal found 2/11![Spirit Airlines logo]()
$492
This LATAM Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2810:11 am
STL
- GYE
2 stops20h 37m
LATAM Airlines
Wed 3/42:25 pm
GYE
- STL
2 stops28h 17m
LATAM Airlines
Deal found 2/11![LATAM Airlines logo]()
$1,012
This Priceline deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/811:26 am
MCI
- GYE
1 stop11h 38m
Spirit Airlines
Wed 3/1811:59 pm
GYE
- MCI
1 stop11h 30m
Spirit Airlines
Deal found 2/11![Spirit Airlines logo]()
$546
This United Airlines deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/286:00 am
STL
- GYE
2 stops13h 46m
United Airlines
Wed 3/412:20 pm
GYE
- STL
2 stops22h 01m
United Airlines
Deal found 2/12![United Airlines logo]()
$893
This Mytrip deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/304:05 pm
STL
- GYE
3 stops31h 25m
Multiple Airlines
Mon 4/66:50 pm
GYE
- STL
2 stops20h 34m
Multiple Airlines
Deal found 2/13![Multiple Airlines logo]()
$1,951
Last-minute flights from Missouri to GuayaquilDiscover last-minute flight deals from Missouri to Guayaquil. Data last updated February 14, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Guayaquil. Data last updated February 14, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/286:00 am
STL
- GYE
2 stops13h 46m
United Airlines
Wed 3/412:20 pm
GYE
- STL
2 stops22h 01m
United Airlines
Deal found 2/12![United Airlines logo]()
$893
This LATAM Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2810:11 am
STL
- GYE
2 stops20h 37m
LATAM Airlines
Wed 3/42:25 pm
GYE
- STL
2 stops28h 17m
LATAM Airlines
Deal found 2/11![LATAM Airlines logo]()
$1,012
This Priceline deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/811:26 am
MCI
- GYE
1 stop11h 38m
Spirit Airlines
Wed 3/1811:59 pm
GYE
- MCI
1 stop11h 30m
Spirit Airlines
Deal found 2/11![Spirit Airlines logo]()
$546
This FlightHub deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/2112:24 pm
MCI
- GYE
1 stop10h 40m
Spirit Airlines
Sat 3/2811:59 pm
GYE
- MCI
1 stop11h 30m
Spirit Airlines
Deal found 2/10![Spirit Airlines logo]()
$334
This KAYAK deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2712:24 pm
MCI
- GYE
1 stop10h 40m
Spirit Airlines
Fri 4/1011:59 pm
GYE
- MCI
2 stops23h 54m
Spirit Airlines
Deal found 2/11![Spirit Airlines logo]()
$492
This United Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/306:00 am
STL
- GYE
2 stops17h 39m
United Airlines
Mon 4/68:28 am
GYE
- STL
2 stops24h 57m
United Airlines
Deal found 2/13![United Airlines logo]()
$639
This American Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/305:15 am
STL
- GYE
1 stop8h 15m
American Airlines
Mon 4/62:30 pm
GYE
- STL
1 stop19h 46m
American Airlines
Deal found 2/13![American Airlines logo]()
$708
This Mytrip deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/304:05 pm
STL
- GYE
3 stops31h 25m
Multiple Airlines
Mon 4/66:50 pm
GYE
- STL
2 stops20h 34m
Multiple Airlines
Deal found 2/13![Multiple Airlines logo]()
$1,951
One-way flights from Missouri to GuayaquilSearch for one-way flight options from Missouri to Guayaquil. Find affordable one-way fares based on user searches. Data last updated February 14, 2026.
Search for one-way flight options from Missouri to Guayaquil. Find affordable one-way fares based on user searches. Data last updated February 14, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/104:24 pm
MCI
- GYE
2 stops30h 40m
Spirit Airlines
Deal found 2/11![Spirit Airlines logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1111:45 am
MCI
- GYE
2 stops35h 19m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$214
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/104:24 pm
MCI
- GYE
3 stops31h 31m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$248
This FlightHub deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1911:26 am
MCI
- GYE
1 stop11h 38m
Spirit Airlines
Deal found 2/12![Spirit Airlines logo]()
$280
This KAYAK deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/218:30 am
STL
- GYE
2 stops14h 25m
Copa Airlines
Deal found 2/9![Copa Airlines logo]()
$387
This KAYAK deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/199:10 am
MCI
- GYE
2 stops13h 45m
Copa Airlines
Deal found 2/11![Copa Airlines logo]()
$387
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/128:40 pm
MCI
- GYE
3 stops26h 24m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$388
This Gurufare deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/197:41 am
STL
- GYE
2 stops15h 14m
Copa Airlines
Deal found 2/13![Copa Airlines logo]()
$393
This United Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:00 am
STL
- GYE
2 stops14h 54m
United Airlines
Deal found 2/13![United Airlines logo]()
$405
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/109:35 am
MCI
- GYE
1 stop21h 45m
Delta
Deal found 2/11![Delta logo]()
$414
This Expedia deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2212:12 pm
MCI
- GYE
1 stop10h 43m
Spirit Airlines
Deal found 2/11![Spirit Airlines logo]()
$432
This Avianca Connect deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/236:00 am
MCI
- GYE
2 stops18h 45m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$437
Find flight deals from Missouri to Guayaquil
Keep the following information in mind while searching for Missouri to Guayaquil flight deals. Data was last updated February 14, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $334 (FlightHub) |
One-way from | $209 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 14, 2026.
Use the filters below to find and compare flights from Missouri to Guayaquil that are best for you.
Fly from
Missouri
Fly to
Guayaquil
Route
Depart
Return
Price
Kansas CityGuayaquil
MCI - GYE
MCIGYE
Kansas City
Sat 3/21
12:24 pm-11:04 pm
1 stop10h 40m
Guayaquil Jose Joaquin de Olmedo
Sat 3/28
11:59 pm-11:29 am
1 stop11h 30m
$334
Kansas CityGuayaquil
MCI - GYE
MCIGYE
Kansas City
Fri 3/27
12:24 pm-11:04 pm
1 stop10h 40m
Guayaquil Jose Joaquin de Olmedo
Fri 4/10
11:59 pm-11:53 pm
2 stops23h 54m
$492
Kansas CityGuayaquil
MCI - GYE
MCIGYE
Kansas City
Sun 3/8
11:26 am-11:04 pm
1 stop11h 38m
Guayaquil Jose Joaquin de Olmedo
Wed 3/18
11:59 pm-11:29 am
1 stop11h 30m
$546
St. LouisGuayaquil
STL - GYE
STLGYE
Lambert-St Louis
Mon 3/30
6:00 am-11:39 pm
2 stops17h 39m
Guayaquil Jose Joaquin de Olmedo
Mon 4/6
8:28 am-9:25 am
2 stops24h 57m
$639
St. LouisGuayaquil
STL - GYE
STLGYE
Lambert-St Louis
Mon 3/30
5:15 am-1:30 pm
1 stop8h 15m
Guayaquil Jose Joaquin de Olmedo
Mon 4/6
2:30 pm-10:16 am
1 stop19h 46m
$708
St. LouisGuayaquil
STL - GYE
STLGYE
Lambert-St Louis
Sat 2/28
6:00 am-8:46 pm
2 stops13h 46m
Guayaquil Jose Joaquin de Olmedo
Wed 3/4
12:20 pm-9:21 am
2 stops22h 01m
$893
St. LouisGuayaquil
STL - GYE
STLGYE
Lambert-St Louis
Sat 2/28
10:11 am-7:48 am
2 stops20h 37m
Guayaquil Jose Joaquin de Olmedo
Wed 3/4
2:25 pm-5:42 pm
2 stops28h 17m
$1,012
St. LouisGuayaquil
STL - GYE
STLGYE
Lambert-St Louis
Mon 3/30
4:05 pm-11:30 pm
3 stops31h 25m
Guayaquil Jose Joaquin de Olmedo
Mon 4/6
6:50 pm-3:24 pm
2 stops20h 34m
$1,951
Kansas CityGuayaquil
MCI - GYE
MCIGYE
Kansas City
Tue 3/10
4:24 pm-11:04 pm
2 stops30h 40m
$209
Kansas CityGuayaquil
MCI - GYE
MCIGYE
Kansas City
Wed 3/11
11:45 am-11:04 pm
2 stops35h 19m
$214
Showing 1-10 of 20 results
Best time to book a flight from Missouri to Guayaquil
Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Missouri with our price prediction graph.
MCI-GYE
STL-GYE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Guayaquil
USMO-GYE
MCI-GYE
STL-GYE
No data available for this route at this time. Please check back soon.
Related info for your journey
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Other flights to Guayaquil
Explore flights to Guayaquil departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on February 14, 2026.
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Consider these flights traveling from Missouri to Guayaquil.
Top airline flying from Missouri to Guayaquil
Discover the top airline that operate flights from Missouri to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 14, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$516 | Average$996 | FlexibilityNo cancel fee | On-time71% |