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Guayaquil

$251+ Cheap flights from Mexico City (MEX) to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/9. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — GYE
May 5 — May 121
Tue 5/5
Tue 5/12
1 adult, Economy
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Cheap flight deals from Mexico City to Guayaquil

Cheapest flights from Mexico City to Guayaquil
Explore the most affordable flight options available from Mexico City to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 5, 2026.

This Avianca deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2311:20 pm
MEX
-
GYE
2 stops11h 00m
Avianca
Mon 4/271:40 pm
GYE
-
MEX
1 stop13h 20m
Avianca
Deal found 4/4$448
This Avianca deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:00 am
MEX
-
GYE
1 stop12h 50m
Avianca
Sun 4/193:00 pm
GYE
-
MEX
2 stops12h 00m
Avianca
Deal found 4/2$470
This FlightHub deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:40 am
MEX
-
GYE
2 stops15h 55m
Avianca
Mon 4/276:50 pm
GYE
-
MEX
1 stop18h 20m
Avianca
Deal found 4/4$499
This FlightHub deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/224:55 pm
MEX
-
GYE
2 stops13h 35m
Avianca
Sun 4/266:50 pm
GYE
-
MEX
1 stop9h 15m
Avianca
Deal found 4/4$501
This Kiwi.com deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/195:50 am
MEX
-
GYE
1 stop6h 43m
Copa Airlines
Tue 5/266:28 pm
GYE
-
MEX
1 stop6h 47m
Copa Airlines
Deal found 4/4$508
This Avianca deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/304:55 am
MEX
-
GYE
1 stop8h 40m
Avianca
Sun 5/1010:05 am
GYE
-
MEX
1 stop9h 00m
Avianca
Deal found 4/3$515
This Avianca deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2411:20 pm
MEX
-
GYE
1 stop8h 35m
Avianca
Sat 9/129:10 am
GYE
-
MEX
1 stop14h 50m
Avianca
Deal found 4/1$517
This Copa Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/303:30 pm
MEX
-
GYE
1 stop18h 50m
Copa Airlines
Sun 5/1012:22 pm
GYE
-
MEX
1 stop13h 38m
Copa Airlines
Deal found 4/2$520
This Avianca deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/194:55 am
MEX
-
GYE
1 stop8h 40m
Avianca
Fri 10/233:30 am
GYE
-
MEX
1 stop15h 35m
Avianca
Deal found 4/1$527

Find flight deals from Mexico City to Guayaquil

Discover tips and strategies to find the most affordable flight options for your journey from Mexico City (MEX) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 5, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$448
(Avianca)

One-way from

$251
(Avianca)

Popular in

December

Cheapest in

February

Average price

$452
Provider with most accurate pricing for Mexico City Benito Juarez-Guayaquil Jose Joaquin de Olmedo flight deals.
Search Deals
Provider most trusted by Cheapflights users for Mexico City Benito Juarez-Guayaquil Jose Joaquin de Olmedo flights.
Search Deals
From Mexico City Benito Juarez to Guayaquil Jose Joaquin de Olmedo
Search Deals
One-way flight from Mexico City Benito Juarez to Guayaquil Jose Joaquin de Olmedo
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($11 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 0% potential price decrease ($5 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mexico City to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 5, 2026.
Use the filters below to find and compare flights from Mexico City to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Mexico CityGuayaquil

MEX - GYE

MEXGYE

Mexico City Benito Juarez

Sat 5/2

11:20 pm-2:35 pm

1 stop14h 15m

Guayaquil Jose Joaquin de Olmedo

Tue 5/5

4:40 pm-3:05 am

2 stops11h 25m

$470

Mexico CityGuayaquil

MEX - GYE

MEXGYE

Mexico City Benito Juarez

Mon 8/24

11:20 pm-2:35 pm

1 stop14h 15m

Guayaquil Jose Joaquin de Olmedo

Sat 9/12

9:10 am-6:05 pm

1 stop9h 55m

$518

Mexico CityGuayaquil

MEX - GYE

MEXGYE

Mexico City Benito Juarez

Thu 4/30

4:55 am-2:35 pm

1 stop8h 40m

Guayaquil Jose Joaquin de Olmedo

Sun 5/10

9:05 am-6:05 pm

1 stop10h 00m

$518

Mexico CityGuayaquil

MEX - GYE

MEXGYE

Mexico City Benito Juarez

Thu 4/30

3:30 pm-11:20 am

1 stop18h 50m

Guayaquil Jose Joaquin de Olmedo

Sun 5/10

12:22 pm-1:00 am

1 stop13h 38m

$520

Mexico CityGuayaquil

MEX - GYE

MEXGYE

Mexico City Benito Juarez

Mon 7/13

1:20 am-1:35 pm

1 stop11h 15m

Guayaquil Jose Joaquin de Olmedo

Wed 7/29

12:21 pm-1:00 am

1 stop13h 39m

$539
Quickest round-trip

Mexico CityGuayaquil

MEX - GYE

MEXGYE

Mexico City Benito Juarez

Tue 6/30

12:25 am-11:22 am

1 stop9h 57m

Guayaquil Jose Joaquin de Olmedo

Wed 7/8

12:21 pm-7:05 pm

1 stop7h 44m

$539

Mexico CityGuayaquil

MEX - GYE

MEXGYE

Mexico City Benito Juarez

Wed 6/3

2:10 am-11:20 am

1 stop8h 10m

Guayaquil Jose Joaquin de Olmedo

Mon 6/8

4:28 am-1:00 am

1 stop21h 32m

$539

Mexico CityGuayaquil

MEX - GYE

MEXGYE

Mexico City Benito Juarez

Mon 4/20

2:10 am-11:22 am

1 stop8h 12m

Guayaquil Jose Joaquin de Olmedo

Sat 4/25

8:28 am-7:05 pm

1 stop11h 37m

$540
Cheapest one-way

Mexico CityGuayaquil

MEX - GYE

MEXGYE

Mexico City Benito Juarez

Thu 4/9

12:40 am-5:35 pm

1 stop15h 55m

$251

Mexico CityGuayaquil

MEX - GYE

MEXGYE

Mexico City Benito Juarez

Fri 4/10

12:40 am-2:35 pm

1 stop12h 55m

$251

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/31

Showing 1-10 of 14 resultsSorted by cheapest first
1
2
  • Most accurate provider: When it comes to deals on Mexico City-Guayaquil flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Mexico City-Guayaquil flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Mexico City-Guayaquil flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Mexico City-Guayaquil flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Mexico City-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Mexico City to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Mexico City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico City to Guayaquil

How far ahead should I book a flight from Mexico City to Guayaquil?

Use this chart to determine the optimal time to book a round-trip flight from Mexico City to Guayaquil. Price data was last updated on April 2, 2026.

To ensure you get the cheapest price possible for a flight from Mexico City to Guayaquil, you should look to book at least 86 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Mexico City to Guayaquil?

Currently, December is the cheapest month in which you can book a flight from Mexico City to Guayaquil (average of $286). Flying from Mexico City to Guayaquil in November is currently the most expensive (average of $415). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Mexico City to Guayaquil?

Reviews of airlines servicing Guayaquil

Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated April 5, 2026.
Read reviews from past customers who have flown Copa Airlines and Avianca from Mexico City to Guayaquil. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,576 reviews

Crew

8.1

Comfort

7.4

Food

6.8

Overall

7.5

Boarding

7.8

Entertainment

6.8

Reviews

1 / 20
2.0
Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it
Copa Airlines
7.5
Good
1,576 reviews
Copa Airlines
7.5
Good
1,576 reviews

Crew

8.1

Comfort

7.4

Food

6.8

Overall

7.5

Boarding

7.8

Entertainment

6.8

Reviews

1 / 20
2.0
Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it
Avianca
6.5
Okay
2,505 reviews
Copa Airlines
7.5
Good
1,576 reviews

Crew

8.1

Comfort

7.4

Food

6.8

Overall

7.5

Boarding

7.8

Entertainment

6.8

Reviews

1 / 20
2.0
Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it

Related info for your journey

Find useful and relevant information for your journey from Mexico City to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mexico City to Guayaquil?

    Avianca and Copa Airlines can get you from Mexico City to Guayaquil in just under 14h 15m. Your travel time can differ by up to 4h 35m. The distance between Mexico City and Guayaquil is about 1979 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Mexico City to Guayaquil round-trip?

    Flying on Copa Airlines is currently your cheapest option to Guayaquil, with prices starting at $360. Another option worth looking into is Avianca, starting at $415 round trip. These flights start at 21% lower than the current average price 3 months from now.

  • Can I find deals for flights from Mexico City to Guayaquil that include hotel bookings?

    Yes. In addition to deals on Mexico City to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico City to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City to Guayaquil.

  • Can I find deals for business class flights from Mexico City to Guayaquil?

    Yes. Cheapflights offers flight deals from Mexico City to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico City to Guayaquil?

    Currently, December is the cheapest month in which you can book a flight from Mexico City to Guayaquil (average of $286). Flying from Mexico City to Guayaquil in November is currently the most expensive (average of $415). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Mexico City to Guayaquil

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Mexico City to Guayaquil

Discover the top 2 airlines that operate flights from Mexico City to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 5, 2026.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$360Average$555FlexibilityNo cancel feeOn-time70%
AviancaCheapest$415Average$469FlexibilityNo cancel feeOn-time71%

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