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Guayaquil

$211+ Cheap flights from Iowa to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/13. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GYE
Mar 13 — Mar 201
Fri 3/13
Fri 3/20
1 adult, Economy
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Cheap flight deals from Iowa to Guayaquil

Cheapest flights from Iowa to Guayaquil
Explore the most affordable flight options available from Iowa to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 11, 2026.

This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/266:00 am
DSM
-
GYE
1 stop17h 04m
Multiple Airlines
Thu 4/27:05 pm
GYE
-
DSM
2 stops24h 09m
Multiple Airlines
Deal found 2/9$542
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/118:21 pm
DSM
-
GYE
2 stops33h 14m
Multiple Airlines
Mon 3/1611:59 pm
GYE
-
DSM
1 stop12h 34m
Multiple Airlines
Deal found 2/11$673
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/265:17 pm
OMA
-
GYE
2 stops20h 13m
American Airlines
Thu 4/26:12 am
GYE
-
OMA
1 stop17h 47m
American Airlines
Deal found 2/9$725
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/236:15 am
OMA
-
GYE
1 stop15h 29m
American Airlines
Wed 3/256:12 am
GYE
-
OMA
1 stop17h 47m
American Airlines
Deal found 2/9$734
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/273:26 pm
DSM
-
GYE
2 stops22h 04m
American Airlines
Fri 4/36:12 am
GYE
-
DSM
1 stop17h 44m
American Airlines
Deal found 2/10$751
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/117:44 pm
DSM
-
GYE
2 stops17h 46m
American Airlines
Mon 3/166:12 am
GYE
-
DSM
2 stops17h 28m
American Airlines
Deal found 2/11$789
This United Airlines deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/88:10 am
DSM
-
GYE
2 stops32h 25m
United Airlines
Wed 2/118:34 am
GYE
-
DSM
2 stops38h 46m
United Airlines
Deal found 2/7$853
This United Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/127:52 am
DSM
-
GYE
2 stops35h 54m
United Airlines
Mon 2/168:34 am
GYE
-
DSM
2 stops38h 46m
United Airlines
Deal found 2/11$875
This KAYAK deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/122:59 pm
DSM
-
GYE
2 stops28h 47m
Multiple Airlines
Mon 2/166:55 pm
GYE
-
DSM
2 stops20h 22m
Multiple Airlines
Deal found 2/11$880
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/138:32 pm
DSM
-
GYE
2 stops26h 32m
Multiple Airlines
Mon 3/1611:59 pm
GYE
-
DSM
1 stop12h 34m
Multiple Airlines
Deal found 2/11$898
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/238:15 am
OMA
-
GYE
2 stops14h 27m
United Airlines
Thu 2/262:35 pm
GYE
-
OMA
2 stops32h 52m
United Airlines
Deal found 2/8$909
This United Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/117:15 am
DSM
-
GYE
2 stops16h 26m
United Airlines
Mon 3/1612:20 pm
GYE
-
DSM
3 stops27h 47m
United Airlines
Deal found 2/11$960

Find flight deals from Iowa to Guayaquil

Keep the following information in mind while searching for Iowa to Guayaquil flight deals. Data was last updated February 11, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$542
(Kiwi.com)

One-way from

$211
(Kiwi.com)
Provider with most accurate pricing for Des Moines-Guayaquil Jose Joaquin de Olmedo flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Guayaquil Jose Joaquin de Olmedo flights.
Search Deals
From Iowa to Guayaquil Jose Joaquin de Olmedo
Search Deals
One-way flight from Iowa to Guayaquil Jose Joaquin de Olmedo
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 11, 2026.
Use the filters below to find and compare flights from Iowa to Guayaquil that are best for you.

Fly from

Iowa

Fly to

Guayaquil

Route

Depart

Return

Price

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Thu 3/26

6:00 am-11:04 pm

1 stop17h 04m

Guayaquil Jose Joaquin de Olmedo

Thu 4/2

7:05 pm-7:14 pm

2 stops24h 09m

$542

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Wed 3/11

8:21 pm-5:35 am

2 stops33h 14m

Guayaquil Jose Joaquin de Olmedo

Mon 3/16

11:59 pm-12:33 pm

1 stop12h 34m

$673

OmahaGuayaquil

OMA - GYE

OMAGYE

Omaha Eppley Airfield

Thu 3/26

5:17 pm-1:30 pm

2 stops20h 13m

Guayaquil Jose Joaquin de Olmedo

Thu 4/2

6:12 am-11:59 pm

1 stop17h 47m

$725

OmahaGuayaquil

OMA - GYE

OMAGYE

Omaha Eppley Airfield

Mon 3/23

6:15 am-9:44 pm

1 stop15h 29m

Guayaquil Jose Joaquin de Olmedo

Wed 3/25

6:12 am-11:59 pm

1 stop17h 47m

$734

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Fri 3/27

1:52 pm-1:30 pm

2 stops23h 38m

Guayaquil Jose Joaquin de Olmedo

Fri 4/3

2:30 pm-2:56 pm

2 stops24h 26m

$751

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Wed 3/11

7:00 am-9:44 pm

1 stop14h 44m

Guayaquil Jose Joaquin de Olmedo

Mon 3/16

6:12 am-11:56 pm

1 stop17h 44m

$841

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Fri 3/13

8:32 pm-11:04 pm

2 stops26h 32m

Guayaquil Jose Joaquin de Olmedo

Mon 3/16

11:59 pm-12:33 pm

1 stop12h 34m

$898

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Wed 3/11

7:15 am-11:41 pm

2 stops16h 26m

Guayaquil Jose Joaquin de Olmedo

Mon 3/16

12:20 pm-4:07 pm

3 stops27h 47m

$960

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Thu 3/26

7:45 am-9:44 pm

2 stops13h 59m

Guayaquil Jose Joaquin de Olmedo

Thu 4/2

6:12 am-9:59 pm

2 stops15h 47m

$993

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Mon 4/13

8:14 pm-11:04 pm

3 stops50h 50m

$211

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/10

Showing 1-10 of 15 results
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Best time to book a flight from Iowa to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Guayaquil
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Guayaquil from Iowa?

    Most people fly into Guayaquil Jose Joaquin de Olmedo (GYE) if they book a flight to Guayaquil from Iowa. Jose Joaquin de Olmedo is conveniently located just 2.5 mi from Guayaquil’s city center.

  • How long is the flight from Iowa to Guayaquil?

    A quick flight from Iowa to Guayaquil can take about 20h 13m. American Airlines provides one of the quickest options available for as low as $725. Airlines will cover a distance of 3165 mi.

  • Can I find deals for flights from Iowa to Guayaquil that include hotel bookings?

    Yes. In addition to deals on Iowa to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Guayaquil.

  • Can I find deals for business class flights from Iowa to Guayaquil?

    Yes. Cheapflights offers flight deals from Iowa to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Iowa to Guayaquil

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