HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Guayaquil

$433+ Cheap flights from Iowa to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/19. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GYE
Jan 20 — Jan 271
Tue 1/20
Tue 1/27
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Iowa to Guayaquil with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Iowa to Guayaquil

Cheapest flights from Iowa to Guayaquil
Explore the most affordable flight options available from Iowa to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 21, 2025.

This United Airlines deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/296:00 amDSM - GYE
2 stops13h 43mUnited Airlines
Tue 12/3012:20 pmGYE - DSM
2 stops23h 30mUnited Airlines
Deal found 12/20$1,161

Find flight deals from Iowa to Guayaquil

Keep the following information in mind while searching for Iowa to Guayaquil flight deals. Data was last updated December 21, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$651
(United Airlines)

One-way from

$433
(American Airlines)
Provider with most accurate pricing for Des Moines-Guayaquil Jose Joaquin de Olmedo flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Guayaquil Jose Joaquin de Olmedo flights.
Search Deals
From Iowa to Guayaquil Jose Joaquin de Olmedo
Search Deals
One-way flight from Iowa to Guayaquil Jose Joaquin de Olmedo
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 21, 2025.
Use the filters below to find and compare flights from Iowa to Guayaquil that are best for you.

Fly from

Iowa

Fly to

Guayaquil

Route

Depart

Return

Price

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Mon 2/2

8:10 am-8:46 pm

2 stops35h 36m

Guayaquil Jose Joaquin de Olmedo

Mon 2/9

8:34 am-2:22 pm

2 stops30h 48m

$651

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Mon 2/2

6:00 am-11:22 pm

2 stops16h 22m

Guayaquil Jose Joaquin de Olmedo

Mon 2/9

7:15 am-11:29 pm

1 stop17h 14m

$662

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Sat 1/31

3:04 pm-5:35 pm

2 stops49h 31m

Guayaquil Jose Joaquin de Olmedo

Sat 2/7

8:34 am-10:30 pm

2 stops14h 56m

$672

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Mon 1/26

8:10 am-8:46 pm

2 stops11h 36m

Guayaquil Jose Joaquin de Olmedo

Thu 1/29

8:34 am-10:30 pm

2 stops38h 56m

$697

OmahaGuayaquil

OMA - GYE

OMAGYE

Omaha Eppley Airfield

Mon 1/19

6:06 am-11:42 pm

2 stops16h 36m

Guayaquil Jose Joaquin de Olmedo

Thu 1/22

8:34 am-10:21 pm

2 stops14h 47m

$706

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Sun 1/25

8:10 am-11:42 pm

2 stops38h 32m

Guayaquil Jose Joaquin de Olmedo

Thu 1/29

12:20 pm-10:30 pm

2 stops35h 10m

$707

OmahaGuayaquil

OMA - GYE

OMAGYE

Omaha Eppley Airfield

Sun 1/25

8:15 am-8:46 pm

2 stops11h 31m

Guayaquil Jose Joaquin de Olmedo

Thu 1/29

2:35 pm-6:54 pm

2 stops29h 19m

$716

OmahaGuayaquil

OMA - GYE

OMAGYE

Omaha Eppley Airfield

Mon 3/23

3:00 pm-1:30 pm

2 stops22h 30m

Guayaquil Jose Joaquin de Olmedo

Wed 3/25

2:30 pm-2:09 pm

2 stops23h 39m

$727

Des MoinesGuayaquil

DSM - GYE

DSMGYE

Des Moines

Sat 1/31

6:30 am-11:22 pm

1 stop15h 52m

Guayaquil Jose Joaquin de Olmedo

Sat 2/7

7:15 am-10:50 am

2 stops28h 35m

$909

OmahaGuayaquil

OMA - GYE

OMAGYE

Omaha Eppley Airfield

Tue 5/19

6:13 pm-1:33 pm

2 stops19h 20m

$433

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/18

Showing 1-10 of 11 results
1
2

Best time to book a flight from Iowa to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Guayaquil
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Guayaquil from Iowa?

    Most people fly into Guayaquil Jose Joaquin de Olmedo (GYE) if they book a flight to Guayaquil from Iowa. Jose Joaquin de Olmedo is conveniently located just 2.5 mi from Guayaquil’s city center.

  • How long is the flight from Iowa to Guayaquil?

    A quick flight from Iowa to Guayaquil can take about 16h 22m. United Airlines provides one of the quickest options available for as low as $662. Airlines will cover a distance of 3138 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Iowa to Guayaquil that include hotel bookings?

    Yes. In addition to deals on Iowa to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Guayaquil.

  • Can I find deals for business class flights from Iowa to Guayaquil?

    Yes. Cheapflights offers flight deals from Iowa to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Iowa to Guayaquil

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Guayaquil flights
John F Kennedy Intl to Quito flights
Newark to Guayaquil flights
Newark to Quito flights
LaGuardia to Quito flights
LaGuardia to Guayaquil flights
Miami to Quito flights
Miami to Guayaquil flights
John F Kennedy Intl to Cuenca flights
Fort Lauderdale to Guayaquil flights
O'Hare Intl to Quito flights
Dulles Intl to Quito flights
Atlanta to Quito flights
Minneapolis to Quito flights
Boston to Quito flights
Hobby to Quito flights
San Francisco to Quito flights
George Bush Intcntl to Quito flights
Los Angeles to Quito flights
O'Hare Intl to Guayaquil flights
Dulles Intl to Guayaquil flights
Reagan-National to Quito flights
Dallas/Fort Worth to Quito flights
Baltimore to Quito flights
Fort Lauderdale to Quito flights
Boston to Guayaquil flights
Denver to Quito flights
Orlando to Guayaquil flights
Tampa to Quito flights
Nashville to Quito flights
Austin to Quito flights
Raleigh to Quito flights
Hobby to Guayaquil flights
Dallas/Fort Worth to Guayaquil flights
John F Kennedy Intl to Manta flights
John F Kennedy Intl to Baltra flights
Los Angeles to Guayaquil flights
Orlando to Quito flights
Seattle to Quito flights
Tampa to Guayaquil flights
Portland to Quito flights
Baltimore to Guayaquil flights
Sky Harbor Intl to Quito flights
Reagan-National to Guayaquil flights
Midway to Quito flights
George Bush Intcntl to Guayaquil flights
Salt Lake City to Quito flights
LaGuardia to Cuenca flights
Charlotte to Guayaquil flights
Minneapolis to Guayaquil flights

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.