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Guatemala

$143+ Cheap flights from Knoxville (TYS) to Guatemala

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/23. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — GUA
Mar 8 — Mar 151
Sun 3/8
Sun 3/15
1 adult, Economy
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Cheap flight deals from Knoxville to Guatemala

Cheapest flights from Knoxville to Guatemala
Explore the most affordable flight options available from Knoxville to Guatemala. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 6, 2026.

This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/202:06 pm
TYS
-
GUA
1 stop22h 14m
Multiple Airlines
Thu 4/212:23 pm
GUA
-
TYS
1 stop17h 47m
Multiple Airlines
Deal found 2/2$372
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/43:54 pm
TYS
-
GUA
1 stop21h 30m
Multiple Airlines
Wed 3/118:10 pm
GUA
-
TYS
2 stops12h 34m
Multiple Airlines
Deal found 2/3$446
This Kiwi.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/237:40 am
TYS
-
GUA
1 stop18h 24m
Multiple Airlines
Mon 3/302:25 pm
GUA
-
TYS
2 stops44h 20m
Multiple Airlines
Deal found 2/6$498
This American Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:00 am
TYS
-
GUA
1 stop8h 46m
American Airlines
Thu 5/2112:32 am
GUA
-
TYS
1 stop10h 29m
American Airlines
Deal found 2/6$505
This Kiwi.com deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2312:54 pm
TYS
-
GUA
1 stop23h 33m
Multiple Airlines
Sun 5/318:15 pm
GUA
-
TYS
2 stops22h 58m
Multiple Airlines
Deal found 2/5$525
This Kiwi.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/149:16 pm
TYS
-
GUA
1 stop28h 48m
Multiple Airlines
Sun 3/2912:23 pm
GUA
-
TYS
1 stop17h 45m
Multiple Airlines
Deal found 2/6$532
This United Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2312:00 pm
TYS
-
GUA
1 stop6h 37m
United Airlines
Tue 6/26:15 am
GUA
-
TYS
1 stop15h 09m
United Airlines
Deal found 2/5$546
This Kiwi.com deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/237:10 am
TYS
-
GUA
2 stops29h 17m
Multiple Airlines
Tue 6/212:29 pm
GUA
-
TYS
1 stop27h 29m
Multiple Airlines
Deal found 2/5$559

Find flight deals from Knoxville to Guatemala

Keep the following information in mind while searching for Knoxville to Guatemala flight deals. Data was last updated February 6, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$372
(Kiwi.com)

One-way from

$143
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$626
Provider with most accurate pricing for Knoxville McGhee Tyson-Guatemala City La Aurora flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Guatemala City La Aurora flights.
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From Knoxville McGhee Tyson to Guatemala
Search Deals
One-way flight from Knoxville McGhee Tyson to Guatemala
Search Deals
Highest demand for flights based on searches. 19% potential increase in price ($150 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($36 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Guatemala that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 6, 2026.
Use the filters below to find and compare flights from Knoxville to Guatemala that are best for you.

Fly from

Knoxville

Fly to

Guatemala

Route

Depart

Return

Price

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Fri 2/20

2:06 pm-11:20 am

1 stop22h 14m

Guatemala City La Aurora

Thu 4/2

12:23 pm-8:10 am

1 stop17h 47m

$372

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Wed 3/4

3:54 pm-12:24 pm

1 stop21h 30m

Guatemala City La Aurora

Wed 3/11

8:10 pm-10:44 am

2 stops12h 34m

$446

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Mon 3/23

7:40 am-12:04 am

1 stop18h 24m

Guatemala City La Aurora

Mon 3/30

2:25 pm-12:45 pm

2 stops44h 20m

$498

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Fri 5/15

6:00 am-12:46 pm

1 stop8h 46m

Guatemala City La Aurora

Thu 5/21

12:32 am-1:01 pm

1 stop10h 29m

$505

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Sat 5/23

12:54 pm-10:27 am

1 stop23h 33m

Guatemala City La Aurora

Sun 5/31

8:15 pm-9:13 pm

2 stops22h 58m

$525

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Sat 3/14

9:16 pm-12:04 am

1 stop28h 48m

Guatemala City La Aurora

Sun 3/29

12:23 pm-8:08 am

1 stop17h 45m

$532

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Sat 5/23

12:00 pm-4:37 pm

1 stop6h 37m

Guatemala City La Aurora

Tue 6/2

6:15 am-11:24 pm

1 stop15h 09m

$546

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Sat 5/23

7:10 am-10:27 am

2 stops29h 17m

Guatemala City La Aurora

Tue 6/2

12:29 pm-5:58 pm

1 stop27h 29m

$559

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Mon 3/23

7:40 am-12:04 am

1 stop18h 24m

$143

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Mon 3/23

5:40 am-11:37 am

1 stop7h 57m

$293

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/3

Best time to book a flight from Knoxville to Guatemala

Have a flexible travel schedule? Discover the best time to fly to Guatemala from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Guatemala

What is the cheapest month to book a flight from Knoxville to Guatemala?

Currently, June is the cheapest month in which you can book a flight from Knoxville to Guatemala (average of $122). Flying from Knoxville to Guatemala in September is currently the most expensive (average of $1,194). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Guatemala

Get insights into the airlines that provide service to Guatemala. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guatemala. Reviews last updated February 6, 2026.
Read through reviews of airlines operating flights from Knoxville to Guatemala, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,162 reviews

Food

7.2

Boarding

8.1

Comfort

7.9

Overall

7.9

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,162 reviews
Delta
7.9
Good
8,162 reviews

Food

7.2

Boarding

8.1

Comfort

7.9

Overall

7.9

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,248 reviews
Delta
7.9
Good
8,162 reviews

Food

7.2

Boarding

8.1

Comfort

7.9

Overall

7.9

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Guatemala. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Guatemala?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Guatemala. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • Can I find deals for flights from Knoxville to Guatemala that include hotel bookings?

    Yes. In addition to deals on Knoxville to Guatemala flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Guatemala?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Guatemala.

  • Can I find deals for business class flights from Knoxville to Guatemala?

    Yes. Cheapflights offers flight deals from Knoxville to Guatemala by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Guatemala?

    Currently, June is the cheapest month in which you can book a flight from Knoxville to Guatemala (average of $122). Flying from Knoxville to Guatemala in September is currently the most expensive (average of $1,194). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Knoxville to Guatemala

Discover the top 2 airlines that operate flights from Knoxville to Guatemala. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 6, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$463Average$626FlexibilityNo cancel feeOn-time71%
DeltaCheapest$571Average$752FlexibilityNo cancel feeOn-timeN/A

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