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Guatemala

$341+ Cheap flights from Knoxville (TYS) to Guatemala

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/23. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — GUA
Jan 9 — Jan 161
Fri 1/9
Fri 1/16
1 adult, Economy
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Cheap flight deals from Knoxville to Guatemala

Cheapest flights from Knoxville to Guatemala
Explore the most affordable flight options available from Knoxville to Guatemala. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 10, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/239:27 pmTYS - GUA
2 stops17h 36mMultiple Airlines
Thu 1/112:20 pmGUA - TYS
1 stop20h 55mMultiple Airlines
Deal found 12/7$559
This Kiwi.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/239:27 pmTYS - GUA
2 stops17h 36mMultiple Airlines
Sun 1/43:00 pmGUA - TYS
1 stop18h 15mMultiple Airlines
Deal found 12/8$652
This Kiwi.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/225:38 pmTYS - GUA
1 stop22h 37mMultiple Airlines
Tue 1/69:40 pmGUA - TYS
2 stops33h 59mMultiple Airlines
Deal found 12/8$717
This Kiwi.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/229:08 amTYS - GUA
2 stops29h 25mMultiple Airlines
Sun 1/43:00 pmGUA - TYS
1 stop18h 15mMultiple Airlines
Deal found 12/8$732
This Kiwi.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/239:27 pmTYS - GUA
1 stop16h 07mMultiple Airlines
Tue 1/69:40 pmGUA - TYS
2 stops33h 59mMultiple Airlines
Deal found 12/8$733
This United Airlines deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/177:05 amTYS - GUA
1 stop13h 34mUnited Airlines
Mon 1/51:28 pmGUA - TYS
1 stop8h 11mUnited Airlines
Deal found 12/8$752
This Kiwi.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/239:27 pmTYS - GUA
2 stops17h 36mMultiple Airlines
Sat 1/31:39 pmGUA - TYS
1 stop17h 39mMultiple Airlines
Deal found 12/8$761

Find flight deals from Knoxville to Guatemala

Keep the following information in mind while searching for Knoxville to Guatemala flight deals. Data was last updated December 10, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$341
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$982
Provider with most accurate pricing for Knoxville McGhee Tyson-Guatemala City La Aurora flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Guatemala City La Aurora flights.
Search Deals
From Knoxville McGhee Tyson to Guatemala
Search Deals
Highest demand for flights based on searches. 16% potential increase in price ($132 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($33 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Guatemala that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 10, 2025.
Use the filters below to find and compare flights from Knoxville to Guatemala that are best for you.

Fly from

Knoxville

Fly to

Guatemala

Route

Depart

Return

Price

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Mon 2/23

12:55 pm-1:11 pm

2 stops25h 16m

Guatemala City La Aurora

Sat 2/28

7:10 pm-10:07 pm

1 stop25h 57m

$341

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Thu 1/22

9:29 am-11:20 am

2 stops26h 51m

Guatemala City La Aurora

Thu 1/29

2:11 pm-5:28 pm

3 stops26h 17m

$392

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Mon 1/12

12:55 pm-11:20 am

1 stop23h 25m

Guatemala City La Aurora

Mon 1/19

8:10 pm-3:57 pm

2 stops42h 47m

$475

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Tue 2/10

6:00 am-2:07 pm

1 stop9h 07m

Guatemala City La Aurora

Wed 2/18

7:00 am-11:55 pm

1 stop15h 55m

$526

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Best time to book a flight from Knoxville to Guatemala

Have a flexible travel schedule? Discover the best time to fly to Guatemala from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Guatemala

What is the cheapest month to book a flight from Knoxville to Guatemala?

Currently, June is the cheapest month in which you can book a flight from Knoxville to Guatemala (average of $122). Flying from Knoxville to Guatemala in September is currently the most expensive (average of $1,194). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Guatemala

Get insights into the airlines that provide service to Guatemala. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guatemala. Reviews last updated December 10, 2025.
Read through reviews of airlines operating flights from Knoxville to Guatemala, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Boarding

8.1

Overall

7.9

Crew

8.5

Food

7.3

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Boarding

8.1

Overall

7.9

Crew

8.5

Food

7.3

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,048 reviews
Delta
7.9
Good
8,007 reviews

Boarding

8.1

Overall

7.9

Crew

8.5

Food

7.3

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Guatemala. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Guatemala?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Guatemala. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • Can I find deals for flights from Knoxville to Guatemala that include hotel bookings?

    Yes. In addition to deals on Knoxville to Guatemala flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Guatemala?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Guatemala.

  • Can I find deals for business class flights from Knoxville to Guatemala?

    Yes. Cheapflights offers flight deals from Knoxville to Guatemala by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Guatemala?

    Currently, June is the cheapest month in which you can book a flight from Knoxville to Guatemala (average of $122). Flying from Knoxville to Guatemala in September is currently the most expensive (average of $1,194). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Knoxville to Guatemala

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Knoxville to Guatemala

Discover the top 2 airlines that operate flights from Knoxville to Guatemala. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 10, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$463Average$655FlexibilityNo cancel feeOn-time71%
DeltaCheapest$504Average$731FlexibilityNo cancel feeOn-timeN/A

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