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Guatemala

$359+ Cheap flights from Knoxville (TYS) to Guatemala

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/11. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — GUA
Nov 13 — Nov 201
Thu 11/13
Thu 11/20
1 adult, Economy
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Cheap flight deals from Knoxville to Guatemala

Keep the following information in mind while searching for Knoxville to Guatemala flight deals. Data was last updated October 14, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$359
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$702
Provider with most accurate pricing for Knoxville McGhee Tyson-Guatemala City La Aurora flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Guatemala City La Aurora flights.
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From Knoxville McGhee Tyson to Guatemala
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Highest demand for flights based on searches. 21% potential increase in price ($176 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($34 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Knoxville to Guatemala

Cheapest flights from Knoxville to Guatemala
Explore the most affordable flight options available from Knoxville to Guatemala. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 14, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1111:24 amTYS - GUA
1 stop26h 02mMultiple Airlines
Tue 11/181:31 pmGUA - TYS
2 stops22h 26mMultiple Airlines
Deal found 10/12$359
This Kiwi.com deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/209:00 amTYS - GUA
2 stops28h 31mMultiple Airlines
Tue 11/41:31 pmGUA - TYS
1 stop25h 11mMultiple Airlines
Deal found 10/13$372
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/282:59 pmTYS - GUA
1 stop21h 20mMultiple Airlines
Fri 12/512:20 pmGUA - TYS
1 stop8h 29mMultiple Airlines
Deal found 10/14$385
This Trip.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/115:45 amTYS - GUA
1 stop24h 15mAvianca
Tue 11/187:10 pmGUA - TYS
1 stop14h 38mAvianca
Deal found 10/12$514

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Guatemala that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 14, 2025.
Use the filters below to find and compare flights from Knoxville to Guatemala that are best for you.

Fly from

Knoxville

Fly to

Guatemala

Route

Depart

Return

Price

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Tue 11/11

11:24 am-12:26 pm

1 stop26h 02m

Guatemala City La Aurora

Tue 11/18

1:31 pm-12:57 pm

2 stops22h 26m

$359

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Fri 11/28

2:59 pm-11:19 am

1 stop21h 20m

Guatemala City La Aurora

Fri 12/5

12:20 pm-9:49 pm

1 stop8h 29m

$385

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Tue 11/11

5:45 am-5:00 am

1 stop24h 15m

Guatemala City La Aurora

Tue 11/18

7:10 pm-10:48 am

1 stop14h 38m

$514

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Tue 3/10

5:30 am-11:45 am

1 stop8h 15m

Guatemala City La Aurora

Wed 3/11

1:10 pm-11:44 pm

1 stop8h 34m

$532

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Tue 11/11

6:06 am-8:16 pm

2 stops15h 10m

Guatemala City La Aurora

Tue 11/18

7:00 am-9:34 pm

2 stops13h 34m

$569

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Tue 3/10

7:04 am-1:10 pm

1 stop8h 06m

Guatemala City La Aurora

Wed 3/11

1:15 pm-11:21 am

2 stops20h 06m

$646

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/12

Best time to book a flight from Knoxville to Guatemala

Have a flexible travel schedule? Discover the best time to fly to Guatemala from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Guatemala

What is the cheapest month to book a flight from Knoxville to Guatemala?

Currently, May is the cheapest month in which you can book a flight from Knoxville to Guatemala (average of $136). Flying from Knoxville to Guatemala in September is currently the most expensive (average of $1,194). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Guatemala

Get insights into the airlines that provide service to Guatemala. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guatemala. Reviews last updated October 14, 2025.
Read through reviews of airlines operating flights from Knoxville to Guatemala, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,975 reviews

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
8.0
Very good
7,975 reviews
Delta
8.0
Very good
7,975 reviews

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,042 reviews
Delta
8.0
Very good
7,975 reviews

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Guatemala. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Guatemala?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Guatemala. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • Can I find deals for flights from Knoxville to Guatemala that include hotel bookings?

    Yes. In addition to deals on Knoxville to Guatemala flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Guatemala?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Guatemala.

  • Can I find deals for business class flights from Knoxville to Guatemala?

    Yes. Cheapflights offers flight deals from Knoxville to Guatemala by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Guatemala?

    Currently, May is the cheapest month in which you can book a flight from Knoxville to Guatemala (average of $136). Flying from Knoxville to Guatemala in September is currently the most expensive (average of $1,194). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Knoxville to Guatemala

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Knoxville to Guatemala

Discover the top 2 airlines that operate flights from Knoxville to Guatemala. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$492Average$814FlexibilityNo cancel feeOn-time71%
DeltaCheapest$504Average$731FlexibilityNo cancel feeOn-timeN/A

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