$358+ Cheap flights from Knoxville (TYS) to Guatemala
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/9. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — GUA
Apr 30 — May 71
Round-trip
1 adult, Economy
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Cheapest flights from Knoxville to GuatemalaExplore the most affordable flight options available from Knoxville to Guatemala. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 31, 2026.
Explore the most affordable flight options available from Knoxville to Guatemala. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 31, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/911:56 am
TYS
- GUA
1 stop25h 16m
Multiple Airlines
Sat 5/165:25 am
GUA
- TYS
2 stops32h 16m
Multiple Airlines
Deal found 3/29![Multiple Airlines logo]()
$398
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/111:26 am
TYS
- GUA
1 stop25h 58m
Multiple Airlines
Mon 4/135:25 am
GUA
- TYS
2 stops10h 05m
Multiple Airlines
Deal found 3/26![Multiple Airlines logo]()
$422
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1411:27 am
TYS
- GUA
2 stops23h 33m
Multiple Airlines
Thu 5/218:00 pm
GUA
- TYS
1 stop18h 40m
Multiple Airlines
Deal found 3/30![Multiple Airlines logo]()
$479
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2210:03 pm
TYS
- GUA
1 stop14h 20m
Multiple Airlines
Sun 5/318:15 pm
GUA
- TYS
2 stops22h 58m
Multiple Airlines
Deal found 3/28![Multiple Airlines logo]()
$489
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/265:00 pm
TYS
- GUA
1 stop19h 23m
Multiple Airlines
Fri 5/295:25 am
GUA
- TYS
2 stops16h 12m
Multiple Airlines
Deal found 3/30![Multiple Airlines logo]()
$490
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/134:25 pm
TYS
- GUA
1 stop20h 47m
Multiple Airlines
Wed 5/2010:15 am
GUA
- TYS
2 stops32h 41m
Multiple Airlines
Deal found 3/29![Multiple Airlines logo]()
$501
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/265:00 pm
TYS
- GUA
1 stop19h 23m
Multiple Airlines
Sat 5/3012:17 pm
GUA
- TYS
2 stops30h 12m
Multiple Airlines
Deal found 3/30![Multiple Airlines logo]()
$502
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/257:24 pm
TYS
- GUA
2 stops17h 48m
Multiple Airlines
Sat 5/3012:17 pm
GUA
- TYS
1 stop21h 56m
Multiple Airlines
Deal found 3/30![Multiple Airlines logo]()
$506
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/171:15 pm
TYS
- GUA
1 stop23h 41m
Multiple Airlines
Mon 4/205:25 am
GUA
- TYS
2 stops10h 05m
Multiple Airlines
Deal found 3/28![Multiple Airlines logo]()
$516
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/257:24 pm
TYS
- GUA
2 stops17h 48m
Multiple Airlines
Fri 5/2911:18 am
GUA
- TYS
1 stop10h 19m
Multiple Airlines
Deal found 3/30![Multiple Airlines logo]()
$518
Best flights from Knoxville to GuatemalaDiscover carefully curated flight deals from Knoxville to Guatemala that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 31, 2026.
Discover carefully curated flight deals from Knoxville to Guatemala that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 31, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/201:01 pm
TYS
- GUA
1 stop24h 11m
Multiple Airlines
Sun 5/2412:17 pm
GUA
- TYS
1 stop28h 17m
Multiple Airlines
Deal found 3/30![Multiple Airlines logo]()
$531
This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:54 pm
TYS
- GUA
1 stop19h 52m
American Airlines
Wed 5/61:01 pm
GUA
- TYS
1 stop8h 58m
American Airlines
Deal found 3/26![American Airlines logo]()
$716
This United Airlines deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/61:35 pm
TYS
- GUA
2 stops23h 50m
United Airlines
Sat 7/111:50 pm
GUA
- TYS
2 stops18h 52m
United Airlines
Deal found 3/28![United Airlines logo]()
$882
This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/237:49 pm
TYS
- GUA
1 stop15h 19m
American Airlines
Thu 6/46:00 am
GUA
- TYS
1 stop11h 04m
American Airlines
Deal found 3/26![American Airlines logo]()
$717
This American Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/237:59 pm
TYS
- GUA
2 stops15h 09m
American Airlines
Wed 6/310:08 am
GUA
- TYS
2 stops11h 39m
American Airlines
Deal found 3/29![American Airlines logo]()
$721
This United Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/139:40 am
TYS
- GUA
1 stop12h 50m
United Airlines
Thu 4/1611:55 pm
GUA
- TYS
2 stops20h 39m
United Airlines
Deal found 3/26![United Airlines logo]()
$907
This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/126:30 am
TYS
- GUA
1 stop14h 13m
American Airlines
Fri 4/173:14 pm
GUA
- TYS
2 stops17h 12m
American Airlines
Deal found 3/26![American Airlines logo]()
$817
Last-minute flights from Knoxville to GuatemalaDiscover last-minute flight deals from Knoxville to Guatemala. Data last updated March 31, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Guatemala. Data last updated March 31, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/111:26 am
TYS
- GUA
1 stop25h 58m
Multiple Airlines
Mon 4/135:25 am
GUA
- TYS
2 stops10h 05m
Multiple Airlines
Deal found 3/26![Multiple Airlines logo]()
$422
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/126:30 am
TYS
- GUA
1 stop7h 20m
American Airlines
Fri 4/171:01 pm
GUA
- TYS
1 stop8h 58m
American Airlines
Deal found 3/27![American Airlines logo]()
$813
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/171:15 pm
TYS
- GUA
1 stop23h 41m
Multiple Airlines
Mon 4/205:25 am
GUA
- TYS
2 stops10h 05m
Multiple Airlines
Deal found 3/28![Multiple Airlines logo]()
$516
This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:00 am
TYS
- GUA
2 stops15h 43m
American Airlines
Fri 4/246:00 am
GUA
- TYS
1 stop15h 59m
American Airlines
Deal found 3/26![American Airlines logo]()
$664
This American Airlines deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:00 am
TYS
- GUA
2 stops15h 43m
American Airlines
Mon 4/206:00 am
GUA
- TYS
2 stops13h 40m
American Airlines
Deal found 3/28![American Airlines logo]()
$815
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/309:25 pm
TYS
- GUA
2 stops39h 31m
Multiple Airlines
Sat 5/1612:17 pm
GUA
- TYS
1 stop24h 48m
Multiple Airlines
Deal found 3/27![Multiple Airlines logo]()
$544
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/305:00 am
TYS
- GUA
2 stops11h 02m
American Airlines
Sat 5/166:00 am
GUA
- TYS
2 stops15h 56m
American Airlines
Deal found 3/27![American Airlines logo]()
$668
One-way flights from Knoxville to GuatemalaSearch for one-way flight options from Knoxville to Guatemala. Find affordable one-way fares based on user searches. Data last updated March 31, 2026.
Search for one-way flight options from Knoxville to Guatemala. Find affordable one-way fares based on user searches. Data last updated March 31, 2026.
This Delta deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/97:27 am
TYS
- GUA
1 stop7h 34m
Delta
Deal found 3/29![Delta logo]()
$358
This American Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/97:00 am
TYS
- GUA
2 stops9h 02m
American Airlines
Deal found 3/29![American Airlines logo]()
$367
This United Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/97:00 am
TYS
- GUA
3 stops15h 30m
United Airlines
Deal found 3/29![United Airlines logo]()
$2,875
Find flight deals from Knoxville to Guatemala
Keep the following information in mind while searching for Knoxville to Guatemala flight deals. Data was last updated March 31, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $398 (Kiwi.com) |
One-way from | $358 (Delta) |
Popular in | December |
Cheapest in | May |
Average price | $532 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Guatemala that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2026.
Use the filters below to find and compare flights from Knoxville to Guatemala that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleGuatemala City
TYS - GUA
TYSGUA
Knoxville McGhee Tyson
Wed 5/20
1:01 pm-11:12 am
1 stop24h 11m
Guatemala City La Aurora
Sun 5/24
12:17 pm-6:34 pm
1 stop28h 17m
$531
KnoxvilleGuatemala City
TYS - GUA
TYSGUA
Knoxville McGhee Tyson
Mon 5/4
6:54 pm-12:46 pm
1 stop19h 52m
Guatemala City La Aurora
Wed 5/6
1:01 pm-11:59 pm
1 stop8h 58m
$716
Quickest round-trip
KnoxvilleGuatemala City
TYS - GUA
TYSGUA
Knoxville McGhee Tyson
Sat 5/23
7:49 pm-9:08 am
1 stop15h 19m
Guatemala City La Aurora
Thu 6/4
6:00 am-7:04 pm
1 stop11h 04m
$717
KnoxvilleGuatemala City
TYS - GUA
TYSGUA
Knoxville McGhee Tyson
Sat 5/23
7:59 pm-9:08 am
2 stops15h 09m
Guatemala City La Aurora
Wed 6/3
10:08 am-11:47 pm
2 stops11h 39m
$721
KnoxvilleGuatemala City
TYS - GUA
TYSGUA
Knoxville McGhee Tyson
Sun 4/12
6:30 am-6:43 pm
1 stop14h 13m
Guatemala City La Aurora
Fri 4/17
3:14 pm-10:26 am
2 stops17h 12m
$817
KnoxvilleGuatemala City
TYS - GUA
TYSGUA
Knoxville McGhee Tyson
Mon 7/6
1:35 pm-11:25 am
2 stops23h 50m
Guatemala City La Aurora
Sat 7/11
1:50 pm-10:42 am
2 stops18h 52m
$882
KnoxvilleGuatemala City
TYS - GUA
TYSGUA
Knoxville McGhee Tyson
Mon 4/13
9:40 am-8:30 pm
1 stop12h 50m
Guatemala City La Aurora
Thu 4/16
11:55 pm-10:34 pm
2 stops20h 39m
$907
Cheapest one-way
Quickest one-way
KnoxvilleGuatemala City
TYS - GUA
TYSGUA
Knoxville McGhee Tyson
Sat 5/9
7:27 am-1:01 pm
1 stop7h 34m
$358
KnoxvilleGuatemala City
TYS - GUA
TYSGUA
Knoxville McGhee Tyson
Fri 5/29
5:45 am-2:30 pm
2 stops10h 45m
$385
KnoxvilleGuatemala City
TYS - GUA
TYSGUA
Knoxville McGhee Tyson
Sat 5/9
7:00 am-8:30 pm
3 stops15h 30m
$2,875
Sorted by cheapest first
Best time to book a flight from Knoxville to Guatemala
Have a flexible travel schedule? Discover the best time to fly to Guatemala from Knoxville with our price prediction graph.
TYS-GUA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Guatemala
TYS-GT0
TYS-GUA
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Guatemala
Get insights into the airlines that provide service to Guatemala. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guatemala. Reviews last updated March 31, 2026.
Read through reviews of airlines operating flights from Knoxville to Guatemala, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Crew
8.5
Boarding
8.1
Food
7.2
Comfort
7.9
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Overall
7.9
Crew
8.5
Boarding
8.1
Food
7.2
Comfort
7.9
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Overall
7.9
Crew
8.5
Boarding
8.1
Food
7.2
Comfort
7.9
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Guatemala. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Knoxville to Guatemala
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Guatemala by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Knoxville to Guatemala by cabin class
Find flights from Knoxville to Guatemala, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Knoxville and Guatemala flights
Browse other Knoxville and Guatemala flight options. Last updated on March 31, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Knoxville to Guatemala
Discover the top 2 airlines that operate flights from Knoxville to Guatemala. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$463 | Average$586 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$571 | Average$731 | FlexibilityNo cancel fee | On-timeN/A |