$203+ Cheap flights from South Carolina to Guatemala City (GUA)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/1. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — GUA
Jun 23 — Jun 301
Round-trip
1 adult, Economy
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Cheapest flights from South Carolina to Guatemala CityExplore the most affordable flight options available from South Carolina to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 24, 2026.
Explore the most affordable flight options available from South Carolina to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 24, 2026.
This JetBlue deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:50 am
CLT
- GUA
1 stop5h 38m
JetBlue
Thu 9/311:33 am
GUA
- CLT
1 stop9h 27m
JetBlue
Deal found 5/21![JetBlue logo]()
$295
This JetBlue deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:50 am
CLT
- GUA
1 stop5h 38m
JetBlue
Thu 9/311:33 am
GUA
- CLT
1 stop7h 36m
JetBlue
Deal found 5/21![JetBlue logo]()
$323
This JetBlue deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:50 am
CLT
- GUA
1 stop5h 38m
JetBlue
Fri 9/411:33 am
GUA
- CLT
1 stop7h 36m
JetBlue
Deal found 5/21![JetBlue logo]()
$330
This Ovago deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:50 am
CLT
- GUA
1 stop5h 38m
JetBlue
Tue 9/1511:40 am
GUA
- CLT
1 stop24h 35m
JetBlue
Deal found 5/21![JetBlue logo]()
$348
This JetBlue deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:50 am
CLT
- GUA
1 stop5h 38m
JetBlue
Thu 9/311:33 am
GUA
- CLT
1 stop7h 36m
JetBlue
Deal found 5/21![JetBlue logo]()
$358
This BusinessClass deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:50 am
CLT
- GUA
1 stop5h 38m
JetBlue
Fri 9/411:33 am
GUA
- CLT
1 stop7h 36m
JetBlue
Deal found 5/21![JetBlue logo]()
$390
This Super.com deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:50 am
CLT
- GUA
1 stop5h 40m
JetBlue
Wed 10/2811:40 am
GUA
- CLT
1 stop7h 29m
JetBlue
Deal found 5/24![JetBlue logo]()
$410
This Travelocity deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:50 am
CLT
- GUA
1 stop5h 38m
Multiple Airlines
Thu 8/203:47 pm
GUA
- CLT
1 stop18h 30m
Multiple Airlines
Deal found 5/20![Multiple Airlines logo]()
$419
This JetBlue deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:50 am
CLT
- GUA
1 stop5h 38m
JetBlue
Sun 9/611:33 am
GUA
- CLT
1 stop7h 36m
JetBlue
Deal found 5/21![JetBlue logo]()
$420
This JetBlue deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:50 am
CLT
- GUA
1 stop5h 38m
JetBlue
Sun 9/611:33 am
GUA
- CLT
1 stop9h 27m
JetBlue
Deal found 5/22![JetBlue logo]()
$427
This JetBlue deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:50 am
CLT
- GUA
1 stop5h 38m
JetBlue
Tue 9/111:33 am
GUA
- CLT
1 stop9h 27m
JetBlue
Deal found 5/21![JetBlue logo]()
$432
This Priceline deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/108:02 pm
CLT
- GUA
1 stop19h 24m
Frontier
Sat 8/293:47 pm
GUA
- CLT
1 stop18h 30m
Frontier
Deal found 5/21![Frontier logo]()
$442
Best flights from South Carolina to Guatemala CityDiscover carefully curated flight deals from South Carolina to Guatemala City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 24, 2026.
Discover carefully curated flight deals from South Carolina to Guatemala City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 24, 2026.
This JetBlue deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:50 am
CLT
- GUA
1 stop5h 38m
JetBlue
Thu 9/311:33 am
GUA
- CLT
1 stop7h 36m
JetBlue
Deal found 5/21![JetBlue logo]()
$358
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:01 am
CHS
- GUA
2 stops14h 21m
American Airlines
Tue 9/151:15 pm
GUA
- CHS
2 stops19h 09m
American Airlines
Deal found 5/19![American Airlines logo]()
$475
This Avianca deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/1511:30 am
SAV
- GUA
1 stop9h 30m
Multiple Airlines
Mon 7/207:10 pm
GUA
- SAV
1 stop11h 38m
Multiple Airlines
Deal found 5/21![Multiple Airlines logo]()
$480
This Copa Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1310:23 am
CLT
- GUA
2 stops13h 48m
Copa Airlines
Fri 11/202:26 am
GUA
- CLT
2 stops30h 18m
Copa Airlines
Deal found 5/21![Copa Airlines logo]()
$548
This United Airlines deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1410:30 am
CLT
- GUA
2 stops10h 19m
United Airlines
Tue 10/271:10 am
GUA
- CLT
1 stop7h 42m
United Airlines
Deal found 5/24![United Airlines logo]()
$608
This Delta deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/125:45 am
AGS
- GUA
1 stop7h 45m
Delta
Mon 10/261:05 pm
GUA
- AGS
1 stop6h 33m
Delta
Deal found 5/21![Delta logo]()
$625
This Copa Airlines deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:00 am
CLT
- GUA
2 stops28h 55m
Copa Airlines
Wed 11/116:24 am
GUA
- CLT
3 stops26h 20m
Copa Airlines
Deal found 5/24![Copa Airlines logo]()
$554
This Avianca deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2212:05 pm
SAV
- GUA
2 stops13h 05m
Multiple Airlines
Wed 8/57:10 pm
GUA
- SAV
1 stop11h 43m
Multiple Airlines
Deal found 5/24![Multiple Airlines logo]()
$574
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/17:50 pm
CHS
- GUA
2 stops15h 22m
American Airlines
Sat 8/152:25 pm
GUA
- CHS
2 stops18h 09m
American Airlines
Deal found 5/19![American Airlines logo]()
$640
This Copa Airlines deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1910:23 am
CLT
- GUA
2 stops24h 11m
Copa Airlines
Sat 11/212:26 am
GUA
- CLT
2 stops30h 18m
Copa Airlines
Deal found 5/24![Copa Airlines logo]()
$583
This Delta deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/105:45 am
AGS
- GUA
1 stop9h 05m
Delta
Mon 10/261:05 pm
GUA
- AGS
1 stop6h 33m
Delta
Deal found 5/21![Delta logo]()
$650
This United Airlines deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/37:47 pm
CHS
- GUA
2 stops27h 53m
United Airlines
Wed 6/101:50 pm
GUA
- CHS
2 stops18h 26m
United Airlines
Deal found 5/24![United Airlines logo]()
$695
This Delta deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/175:46 am
GSP
- GUA
1 stop7h 45m
Delta
Mon 8/3112:53 pm
GUA
- GSP
1 stop8h 45m
Delta
Deal found 5/22![Delta logo]()
$653
This American Airlines deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/134:15 pm
AGS
- GUA
2 stops20h 40m
American Airlines
Mon 10/2612:04 pm
GUA
- AGS
2 stops18h 17m
American Airlines
Deal found 5/23![American Airlines logo]()
$654
This Copa Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:00 am
CLT
- GUA
3 stops17h 36m
Copa Airlines
Thu 11/126:24 am
GUA
- CLT
3 stops26h 20m
Copa Airlines
Deal found 5/20![Copa Airlines logo]()
$624
This United Airlines deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/227:00 am
SAV
- GUA
1 stop9h 30m
United Airlines
Wed 8/511:55 pm
GUA
- SAV
1 stop8h 57m
United Airlines
Deal found 5/24![United Airlines logo]()
$715
This Delta deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:41 am
AGS
- GUA
1 stop7h 50m
Delta
Tue 9/112:53 pm
GUA
- AGS
1 stop9h 03m
Delta
Deal found 5/20![Delta logo]()
$662
This American Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/107:26 pm
SAV
- GUA
2 stops17h 37m
American Airlines
Mon 8/242:25 pm
GUA
- SAV
2 stops19h 41m
American Airlines
Deal found 5/20![American Airlines logo]()
$668
This Copa Airlines deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/1610:27 am
CLT
- GUA
2 stops27h 20m
Copa Airlines
Fri 7/244:28 pm
GUA
- CLT
2 stops24h 34m
Copa Airlines
Deal found 5/23![Copa Airlines logo]()
$657
This American Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/178:13 pm
CHS
- GUA
1 stop14h 59m
American Airlines
Fri 7/2410:12 am
GUA
- CHS
1 stop22h 10m
American Airlines
Deal found 5/22![American Airlines logo]()
$677
This United Airlines deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:35 pm
CAE
- GUA
2 stops23h 02m
United Airlines
Sun 10/251:10 am
GUA
- CAE
2 stops13h 35m
United Airlines
Deal found 5/23![United Airlines logo]()
$749
This Delta deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/315:45 am
GSP
- GUA
1 stop7h 43m
Delta
Mon 9/712:53 pm
GUA
- GSP
1 stop6h 32m
Delta
Deal found 5/22![Delta logo]()
$697
This American Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/268:28 pm
AGS
- GUA
2 stops16h 32m
American Airlines
Sat 10/31:15 pm
GUA
- AGS
2 stops26h 18m
American Airlines
Deal found 5/21![American Airlines logo]()
$679
This United Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1210:18 am
CAE
- GUA
2 stops27h 06m
United Airlines
Mon 10/2610:59 pm
GUA
- CAE
2 stops13h 13m
United Airlines
Deal found 5/21![United Airlines logo]()
$770
This Copa Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/297:55 pm
CLT
- GUA
3 stops27h 42m
Copa Airlines
Sat 9/56:24 am
GUA
- CLT
3 stops25h 20m
Copa Airlines
Deal found 5/21![Copa Airlines logo]()
$710
This American Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:00 am
CHS
- GUA
2 stops14h 21m
American Airlines
Wed 6/1010:08 am
GUA
- CHS
1 stop11h 51m
American Airlines
Deal found 5/20![American Airlines logo]()
$685
This United Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:30 am
CAE
- GUA
2 stops12h 07m
United Airlines
Mon 10/2610:59 pm
GUA
- CAE
2 stops15h 46m
United Airlines
Deal found 5/21![United Airlines logo]()
$774
This Delta deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:44 am
GSP
- GUA
1 stop7h 47m
Delta
Tue 7/1412:56 pm
GUA
- GSP
1 stop8h 58m
Delta
Deal found 5/22![Delta logo]()
$816
This American Airlines deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/247:30 pm
GSP
- GUA
2 stops15h 42m
American Airlines
Wed 7/292:20 pm
GUA
- GSP
2 stops17h 52m
American Airlines
Deal found 5/24![American Airlines logo]()
$687
This United Airlines deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:25 am
CAE
- GUA
2 stops12h 12m
United Airlines
Tue 9/16:15 am
GUA
- CAE
2 stops25h 28m
United Airlines
Deal found 5/24![United Airlines logo]()
$777
Last-minute flights from South Carolina to Guatemala CityDiscover last-minute flight deals from South Carolina to Guatemala City. Data last updated May 24, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Guatemala City. Data last updated May 24, 2026 and is based on user searches.
This Faresmojo deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:15 pm
SAV
- GUA
1 stop12h 45m
Multiple Airlines
Mon 6/17:10 pm
GUA
- SAV
1 stop12h 42m
Multiple Airlines
Deal found 5/23![Multiple Airlines logo]()
$632
This American Airlines deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/288:20 pm
CHS
- GUA
1 stop14h 48m
American Airlines
Sun 5/316:00 am
GUA
- CHS
1 stop11h 29m
American Airlines
Deal found 5/24![American Airlines logo]()
$641
This Copa Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:00 am
CLT
- GUA
2 stops28h 47m
Copa Airlines
Fri 6/51:01 pm
GUA
- CLT
2 stops28h 01m
Copa Airlines
Deal found 5/20![Copa Airlines logo]()
$667
This Copa Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:00 am
CLT
- GUA
2 stops28h 47m
Copa Airlines
Tue 6/210:35 am
GUA
- CLT
2 stops21h 10m
Copa Airlines
Deal found 5/20![Copa Airlines logo]()
$690
This American Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/37:34 pm
CHS
- GUA
1 stop15h 34m
American Airlines
Wed 6/1010:08 am
GUA
- CHS
1 stop11h 51m
American Airlines
Deal found 5/20![American Airlines logo]()
$681
This Travelocity deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/612:08 pm
CLT
- GUA
1 stop28h 42m
Frontier
Thu 6/1111:16 am
GUA
- CLT
1 stop10h 25m
Frontier
Deal found 5/19![Frontier logo]()
$627
This Avianca deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/108:05 am
CLT
- GUA
1 stop12h 55m
Multiple Airlines
Mon 8/245:25 am
GUA
- CLT
2 stops13h 32m
Multiple Airlines
Deal found 5/24![Multiple Airlines logo]()
$657
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/134:24 pm
CLT
- GUA
2 stops30h 27m
Multiple Airlines
Thu 7/92:47 pm
GUA
- CLT
1 stop18h 42m
Multiple Airlines
Deal found 5/20![Multiple Airlines logo]()
$671
This Priceline deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/2012:29 pm
CLT
- GUA
1 stop27h 13m
Frontier
Sat 7/42:47 pm
GUA
- CLT
1 stop18h 42m
Frontier
Deal found 5/23![Frontier logo]()
$607
This Orbitz deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/206:00 am
CLT
- GUA
1 stop30h 01m
Frontier
Sat 7/112:47 pm
GUA
- CLT
1 stop18h 42m
Frontier
Deal found 5/21![Frontier logo]()
$689
This KAYAK deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:18 pm
CHS
- GUA
2 stops16h 50m
GOL
Sun 7/126:00 am
GUA
- CHS
1 stop26h 22m
GOL
Deal found 5/21![GOL logo]()
$671
This Kiwi.com deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/304:24 pm
CLT
- GUA
2 stops30h 27m
Multiple Airlines
Thu 7/92:47 pm
GUA
- CLT
1 stop18h 42m
Multiple Airlines
Deal found 5/22![Multiple Airlines logo]()
$693
One-way flights from South Carolina to Guatemala CitySearch for one-way flight options from South Carolina to Guatemala City. Find affordable one-way fares based on user searches. Data last updated May 24, 2026.
Search for one-way flight options from South Carolina to Guatemala City. Find affordable one-way fares based on user searches. Data last updated May 24, 2026.
This Super.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:50 am
CLT
- GUA
1 stop5h 39m
JetBlue
Deal found 5/20![JetBlue logo]()
$203
This Ovago deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:50 am
CLT
- GUA
1 stop5h 39m
JetBlue
Deal found 5/20![JetBlue logo]()
$207
This JetBlue deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:50 am
CLT
- GUA
1 stop5h 39m
JetBlue
Deal found 5/20![JetBlue logo]()
$212
This Expedia deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/510:59 pm
CLT
- GUA
1 stop16h 43m
Frontier
Deal found 5/23![Frontier logo]()
$242
This Delta deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:30 am
CHS
- GUA
1 stop9h 20m
Delta
Deal found 5/22![Delta logo]()
$247
This American Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/248:08 pm
CHS
- GUA
1 stop18h 37m
American Airlines
Deal found 5/20![American Airlines logo]()
$256
This Copa Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:00 am
CLT
- GUA
2 stops28h 34m
Copa Airlines
Deal found 5/20![Copa Airlines logo]()
$259
This JetBlue deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:50 am
CLT
- GUA
1 stop5h 39m
JetBlue
Deal found 5/20![JetBlue logo]()
$264
This Copa Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1610:23 am
CLT
- GUA
2 stops26h 28m
Copa Airlines
Deal found 5/22![Copa Airlines logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/248:30 pm
GSP
- GUA
2 stops39h 40m
Multiple Airlines
Deal found 5/19![Multiple Airlines logo]()
$271
This American Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1610:45 pm
CLT
- GUA
1 stop15h 02m
American Airlines
Deal found 5/22![American Airlines logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/314:24 pm
CLT
- GUA
2 stops30h 25m
Volaris
Deal found 5/20![Volaris logo]()
$280
Find flight deals from South Carolina to Guatemala City
Keep the following information in mind while searching for South Carolina to Guatemala City flight deals. Data was last updated May 24, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $295 (JetBlue) |
One-way from | $203 (Super.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Guatemala City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 24, 2026.
Use the filters below to find and compare flights from South Carolina to Guatemala City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
CharlotteGuatemala City
CLT - GUA
CLTGUA
Charlotte Douglas
Fri 8/28
6:50 am-10:28 am
1 stop5h 38m
Guatemala City La Aurora
Thu 9/3
11:33 am-9:09 pm
1 stop7h 36m
$358
CharlestonGuatemala City
CHS - GUA
CHSGUA
Charleston
Thu 9/3
7:01 am-7:22 pm
2 stops14h 21m
Guatemala City La Aurora
Tue 9/15
1:15 pm-10:24 am
2 stops19h 09m
$475
SavannahGuatemala City
SAV - GUA
SAVGUA
Savannah/Hilton Head
Wed 7/15
11:30 am-7:00 pm
1 stop9h 30m
Guatemala City La Aurora
Mon 7/20
7:10 pm-8:48 am
1 stop11h 38m
$480
CharlotteGuatemala City
CLT - GUA
CLTGUA
Charlotte Douglas
Fri 11/13
10:23 am-11:11 pm
2 stops13h 48m
Guatemala City La Aurora
Fri 11/20
2:26 am-9:44 am
2 stops30h 18m
$548
CharlotteGuatemala City
CLT - GUA
CLTGUA
Charlotte Douglas
Wed 10/28
6:00 am-8:55 am
2 stops28h 55m
Guatemala City La Aurora
Wed 11/11
6:24 am-9:44 am
3 stops26h 20m
$554
SavannahGuatemala City
SAV - GUA
SAVGUA
Savannah/Hilton Head
Wed 7/22
12:05 pm-11:10 pm
2 stops13h 05m
Guatemala City La Aurora
Wed 8/5
7:10 pm-8:53 am
1 stop11h 43m
$574
CharlotteGuatemala City
CLT - GUA
CLTGUA
Charlotte Douglas
Thu 11/19
10:23 am-9:34 am
2 stops24h 11m
Guatemala City La Aurora
Sat 11/21
2:26 am-9:44 am
2 stops30h 18m
$583
CharlotteGuatemala City
CLT - GUA
CLTGUA
Charlotte Douglas
Wed 10/14
10:30 am-6:49 pm
2 stops10h 19m
Guatemala City La Aurora
Tue 10/27
1:10 am-10:52 am
1 stop7h 42m
$608
CharlotteGuatemala City
CLT - GUA
CLTGUA
Charlotte Douglas
Thu 10/29
6:00 am-9:36 pm
3 stops17h 36m
Guatemala City La Aurora
Thu 11/12
6:24 am-9:44 am
3 stops26h 20m
$624
AugustaGuatemala City
AGS - GUA
AGSGUA
Augusta Bush Field
Mon 10/12
5:45 am-11:30 am
1 stop7h 45m
Guatemala City La Aurora
Mon 10/26
1:05 pm-9:38 pm
1 stop6h 33m
$625
Showing 1-10 of 57 resultsSorted by cheapest first
Best time to book a flight from South Carolina to Guatemala City
Have a flexible travel schedule? Discover the best time to fly to Guatemala City from South Carolina with our price prediction graph.
CLT-GUA
SAV-GUA
CHS-GUA
AGS-GUA
GSP-GUA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Guatemala City
USSC-GUA
CLT-GUA
SAV-GUA
CHS-GUA
AGS-GUA
What is the cheapest month to book a flight from South Carolina to Guatemala City?
Currently, April is the cheapest month in which you can book a flight from South Carolina to Guatemala City (average of $102). Flying from South Carolina to Guatemala City in December is currently the most expensive (average of $558). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from South Carolina to Guatemala City?
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Guatemala City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Guatemala City?
Book flights to Guatemala City if you plan to visit one of these locationsAntigua
Panajachel
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for South Carolina to Guatemala City
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Guatemala City by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Carolina to Guatemala City by cabin class
Find flights from South Carolina to Guatemala City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Guatemala City
Explore flights to Guatemala City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 24, 2026.
South Carolina and Guatemala City flights
Browse other South Carolina and Guatemala City flight options. Last updated on May 24, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
South Carolina to Guatemala City flights
Consider these flights traveling from South Carolina to Guatemala City.
Top 3 airlines flying from South Carolina to Guatemala City
Discover the top 3 airlines that operate flights from South Carolina to Guatemala City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$211 | Average$606 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$402 | Average$779 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$410 | Average$612 | FlexibilityNo cancel fee | On-time71% |