$158+ Cheap flights from South Carolina to Guatemala
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/22. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — GUA
Jun 20 — Jun 271
Round-trip
1 adult, Economy
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Cheapest flights from South Carolina to GuatemalaExplore the most affordable flight options available from South Carolina to Guatemala. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 21, 2026.
Explore the most affordable flight options available from South Carolina to Guatemala. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 21, 2026.
This KAYAK deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:50 am
CLT
- GUA
1 stop5h 38m
JetBlue
Tue 9/1511:40 am
GUA
- CLT
1 stop9h 20m
JetBlue
Deal found 5/20![JetBlue logo]()
$289
This Super.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:50 am
CLT
- GUA
1 stop5h 40m
JetBlue
Sat 9/1911:40 am
GUA
- CLT
1 stop7h 29m
JetBlue
Deal found 5/18![JetBlue logo]()
$409
This Super.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:50 am
CLT
- GUA
1 stop5h 38m
JetBlue
Wed 9/211:33 am
GUA
- CLT
1 stop9h 27m
JetBlue
Deal found 5/19![JetBlue logo]()
$417
This Super.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/186:50 am
CLT
- GUA
1 stop5h 40m
JetBlue
Mon 10/2611:40 am
GUA
- CLT
1 stop7h 29m
JetBlue
Deal found 5/18![JetBlue logo]()
$418
This Travelocity deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:50 am
CLT
- GUA
1 stop5h 38m
Multiple Airlines
Thu 8/203:47 pm
GUA
- CLT
1 stop18h 30m
Multiple Airlines
Deal found 5/20![Multiple Airlines logo]()
$419
This Expedia deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:50 am
CLT
- GUA
1 stop5h 40m
JetBlue
Sun 9/1311:40 am
GUA
- CLT
1 stop24h 35m
JetBlue
Deal found 5/16![JetBlue logo]()
$437
This Priceline deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/108:02 pm
CLT
- GUA
1 stop19h 24m
Frontier
Sat 8/293:47 pm
GUA
- CLT
1 stop18h 30m
Frontier
Deal found 5/21![Frontier logo]()
$442
This Cheapflightsfares deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:50 am
CLT
- GUA
1 stop5h 38m
JetBlue
Mon 8/3111:33 am
GUA
- CLT
1 stop7h 36m
JetBlue
Deal found 5/18![JetBlue logo]()
$444
This JetBlue deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/236:50 am
CLT
- GUA
1 stop5h 38m
JetBlue
Wed 8/2611:33 am
GUA
- CLT
1 stop7h 36m
JetBlue
Deal found 5/17![JetBlue logo]()
$449
This American Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/37:59 pm
CHS
- GUA
1 stop15h 38m
American Airlines
Tue 3/26:40 am
GUA
- CHS
1 stop10h 49m
American Airlines
Deal found 5/16![American Airlines logo]()
$451
This Avianca deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1610:50 am
CHS
- GUA
2 stops13h 20m
Multiple Airlines
Fri 11/207:45 pm
GUA
- CHS
1 stop13h 16m
Multiple Airlines
Deal found 5/17![Multiple Airlines logo]()
$452
This Priceline deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1212:01 pm
CLT
- GUA
1 stop24h 09m
Frontier
Sat 9/53:47 pm
GUA
- CLT
1 stop18h 30m
Frontier
Deal found 5/18![Frontier logo]()
$459
Best flights from South Carolina to GuatemalaDiscover carefully curated flight deals from South Carolina to Guatemala that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 21, 2026.
Discover carefully curated flight deals from South Carolina to Guatemala that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 21, 2026.
This American Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/37:59 pm
CHS
- GUA
1 stop15h 38m
American Airlines
Tue 3/27:00 am
GUA
- CHS
2 stops14h 20m
American Airlines
Deal found 5/16![American Airlines logo]()
$455
This JetBlue deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:50 am
CLT
- GUA
1 stop5h 38m
JetBlue
Tue 9/111:33 am
GUA
- CLT
1 stop9h 27m
JetBlue
Deal found 5/20![JetBlue logo]()
$484
This Copa Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2910:23 am
CLT
- GUA
2 stops14h 48m
Copa Airlines
Wed 11/116:24 am
GUA
- CLT
3 stops26h 20m
Copa Airlines
Deal found 5/20![Copa Airlines logo]()
$543
This Avianca deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1011:30 am
SAV
- GUA
1 stop9h 30m
Multiple Airlines
Mon 8/245:25 am
GUA
- SAV
2 stops12h 10m
Multiple Airlines
Deal found 5/20![Multiple Airlines logo]()
$578
This Delta deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/107:00 am
AGS
- GUA
1 stop7h 50m
Delta
Mon 10/261:05 pm
GUA
- AGS
1 stop6h 33m
Delta
Deal found 5/17![Delta logo]()
$630
This United Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1711:18 am
GSP
- GUA
1 stop12h 22m
United Airlines
Mon 10/266:00 am
GUA
- GSP
1 stop7h 18m
United Airlines
Deal found 5/19![United Airlines logo]()
$635
This KAYAK deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/135:56 pm
SAV
- GUA
2 stops19h 25m
GOL
Sat 6/2712:36 am
GUA
- SAV
1 stop20h 51m
GOL
Deal found 5/16![GOL logo]()
$851
This American Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/33:16 pm
CHS
- GUA
1 stop8h 27m
American Airlines
Mon 11/93:52 pm
GUA
- CHS
1 stop15h 49m
American Airlines
Deal found 5/16![American Airlines logo]()
$521
This American Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/138:43 pm
CHS
- GUA
2 stops16h 17m
American Airlines
Fri 9/187:15 am
GUA
- CHS
1 stop25h 05m
American Airlines
Deal found 5/17![American Airlines logo]()
$535
This Copa Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:47 pm
CLT
- GUA
2 stops17h 04m
Copa Airlines
Mon 11/306:24 am
GUA
- CLT
3 stops26h 20m
Copa Airlines
Deal found 5/16![Copa Airlines logo]()
$599
This Delta deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:41 am
AGS
- GUA
1 stop7h 50m
Delta
Tue 9/112:53 pm
GUA
- AGS
1 stop9h 03m
Delta
Deal found 5/19![Delta logo]()
$633
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/31:13 pm
MYR
- GUA
1 stop27h 28m
Multiple Airlines
Sat 8/223:47 pm
GUA
- MYR
1 stop16h 03m
Multiple Airlines
Deal found 5/18![Multiple Airlines logo]()
$636
This United Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:30 am
CLT
- GUA
1 stop6h 56m
United Airlines
Wed 11/112:10 am
GUA
- CLT
2 stops10h 40m
United Airlines
Deal found 5/20![United Airlines logo]()
$640
This American Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/238:13 pm
CHS
- GUA
1 stop14h 59m
American Airlines
Mon 7/272:20 pm
GUA
- CHS
1 stop18h 02m
American Airlines
Deal found 5/17![American Airlines logo]()
$581
This United Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/127:15 am
CHS
- GUA
1 stop11h 22m
United Airlines
Sun 7/1211:55 pm
GUA
- CHS
1 stop8h 16m
United Airlines
Deal found 5/17![United Airlines logo]()
$647
This Delta deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/125:45 am
AGS
- GUA
1 stop7h 45m
Delta
Mon 10/261:05 pm
GUA
- AGS
1 stop6h 33m
Delta
Deal found 5/16![Delta logo]()
$648
This Copa Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/147:55 pm
CLT
- GUA
2 stops29h 12m
Copa Airlines
Sat 8/224:28 pm
GUA
- CLT
2 stops15h 16m
Copa Airlines
Deal found 5/17![Copa Airlines logo]()
$665
This United Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/136:50 am
CHS
- GUA
1 stop11h 47m
United Airlines
Thu 7/163:45 pm
GUA
- CHS
2 stops16h 38m
United Airlines
Deal found 5/17![United Airlines logo]()
$690
This American Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/124:15 pm
AGS
- GUA
2 stops22h 30m
American Airlines
Mon 10/261:20 pm
GUA
- AGS
2 stops17h 01m
American Airlines
Deal found 5/16![American Airlines logo]()
$634
This Copa Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/137:44 pm
CLT
- GUA
2 stops15h 03m
Copa Airlines
Tue 6/164:24 am
GUA
- CLT
2 stops12h 38m
Copa Airlines
Deal found 5/18![Copa Airlines logo]()
$710
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/273:39 pm
MYR
- GUA
2 stops24h 03m
Multiple Airlines
Sun 7/123:47 pm
GUA
- MYR
1 stop14h 03m
Multiple Airlines
Deal found 5/18![Multiple Airlines logo]()
$820
This United Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/37:47 pm
CHS
- GUA
2 stops27h 53m
United Airlines
Wed 6/1011:55 pm
GUA
- CHS
1 stop8h 21m
United Airlines
Deal found 5/21![United Airlines logo]()
$695
This American Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:18 pm
AGS
- GUA
2 stops18h 37m
American Airlines
Mon 10/261:20 pm
GUA
- AGS
2 stops17h 01m
American Airlines
Deal found 5/16![American Airlines logo]()
$634
This Copa Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/197:44 pm
CLT
- GUA
2 stops15h 03m
Copa Airlines
Sat 6/2710:35 am
GUA
- CLT
2 stops21h 10m
Copa Airlines
Deal found 5/20![Copa Airlines logo]()
$725
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:16 pm
AGS
- GUA
2 stops18h 47m
American Airlines
Tue 9/112:04 pm
GUA
- AGS
2 stops22h 14m
American Airlines
Deal found 5/19![American Airlines logo]()
$637
This United Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:35 pm
CAE
- GUA
2 stops17h 49m
United Airlines
Sun 10/2512:05 am
GUA
- CAE
1 stop7h 42m
United Airlines
Deal found 5/16![United Airlines logo]()
$729
This Copa Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/147:55 pm
CLT
- GUA
3 stops27h 42m
Copa Airlines
Mon 8/316:24 am
GUA
- CLT
3 stops34h 32m
Copa Airlines
Deal found 5/21![Copa Airlines logo]()
$745
This American Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/175:19 pm
GSP
- GUA
2 stops19h 44m
American Airlines
Mon 8/3112:04 pm
GUA
- GSP
1 stop8h 13m
American Airlines
Deal found 5/16![American Airlines logo]()
$639
This United Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:30 am
CAE
- GUA
2 stops12h 07m
United Airlines
Sun 10/251:10 am
GUA
- CAE
2 stops13h 35m
United Airlines
Deal found 5/16![United Airlines logo]()
$754
This Copa Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/17:44 pm
CLT
- GUA
2 stops15h 49m
Copa Airlines
Sat 7/42:28 am
GUA
- CLT
2 stops29h 17m
Copa Airlines
Deal found 5/19![Copa Airlines logo]()
$760
Last-minute flights from South Carolina to GuatemalaDiscover last-minute flight deals from South Carolina to Guatemala. Data last updated May 21, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Guatemala. Data last updated May 21, 2026 and is based on user searches.
This Copa Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:00 am
CLT
- GUA
2 stops19h 08m
Copa Airlines
Fri 6/510:35 am
GUA
- CLT
2 stops30h 27m
Copa Airlines
Deal found 5/18![Copa Airlines logo]()
$665
This American Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/287:50 pm
CHS
- GUA
2 stops15h 18m
American Airlines
Sun 5/316:00 am
GUA
- CHS
1 stop11h 29m
American Airlines
Deal found 5/21![American Airlines logo]()
$675
This Avianca deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/212:50 pm
CLT
- GUA
2 stops12h 20m
Multiple Airlines
Mon 8/318:20 am
GUA
- CLT
1 stop11h 26m
Multiple Airlines
Deal found 5/18![Multiple Airlines logo]()
$650
This Avianca deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/311:05 am
CHS
- GUA
2 stops14h 05m
Multiple Airlines
Wed 6/108:20 am
GUA
- CHS
1 stop11h 31m
Multiple Airlines
Deal found 5/18![Multiple Airlines logo]()
$536
This American Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/37:34 pm
CHS
- GUA
1 stop15h 34m
American Airlines
Wed 6/102:26 pm
GUA
- CHS
2 stops17h 41m
American Airlines
Deal found 5/18![American Airlines logo]()
$630
This Travelocity deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/612:08 pm
CLT
- GUA
1 stop28h 42m
Frontier
Thu 6/1111:16 am
GUA
- CLT
1 stop10h 25m
Frontier
Deal found 5/19![Frontier logo]()
$627
This Avianca deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/108:05 am
CLT
- GUA
1 stop12h 55m
Multiple Airlines
Mon 8/248:20 am
GUA
- CLT
1 stop11h 26m
Multiple Airlines
Deal found 5/20![Multiple Airlines logo]()
$658
This United Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/127:15 am
CHS
- GUA
1 stop11h 22m
United Airlines
Sun 7/1211:55 pm
GUA
- CHS
1 stop8h 16m
United Airlines
Deal found 5/17![United Airlines logo]()
$647
This Ovago deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/127:50 pm
CHS
- GUA
2 stops25h 36m
GOL
Sun 7/122:20 pm
GUA
- CHS
2 stops19h 12m
GOL
Deal found 5/17![GOL logo]()
$660
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/134:24 pm
CLT
- GUA
2 stops30h 27m
Multiple Airlines
Thu 7/92:47 pm
GUA
- CLT
1 stop18h 42m
Multiple Airlines
Deal found 5/20![Multiple Airlines logo]()
$671
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/177:58 pm
CLT
- GUA
1 stop19h 44m
Multiple Airlines
Wed 6/248:27 am
GUA
- CLT
2 stops26h 10m
Multiple Airlines
Deal found 5/18![Multiple Airlines logo]()
$629
This American Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/176:27 pm
AGS
- GUA
2 stops16h 41m
American Airlines
Tue 7/1412:35 am
GUA
- AGS
2 stops19h 34m
American Airlines
Deal found 5/17![American Airlines logo]()
$666
One-way flights from South Carolina to GuatemalaSearch for one-way flight options from South Carolina to Guatemala. Find affordable one-way fares based on user searches. Data last updated May 21, 2026.
Search for one-way flight options from South Carolina to Guatemala. Find affordable one-way fares based on user searches. Data last updated May 21, 2026.
This SmartFares deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:50 am
CLT
- GUA
1 stop5h 40m
JetBlue
Deal found 5/18![JetBlue logo]()
$158
This Super.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:50 am
CLT
- GUA
1 stop5h 39m
JetBlue
Deal found 5/20![JetBlue logo]()
$203
This Ovago deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:50 am
CLT
- GUA
1 stop5h 39m
JetBlue
Deal found 5/20![JetBlue logo]()
$207
This JetBlue deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:50 am
CLT
- GUA
1 stop5h 39m
JetBlue
Deal found 5/20![JetBlue logo]()
$212
This American Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:30 pm
CHS
- GUA
1 stop19h 54m
American Airlines
Deal found 5/17![American Airlines logo]()
$246
This Copa Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2210:25 am
CLT
- GUA
2 stops27h 22m
Copa Airlines
Deal found 5/18![Copa Airlines logo]()
$259
This JetBlue deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:50 am
CLT
- GUA
1 stop5h 39m
JetBlue
Deal found 5/20![JetBlue logo]()
$264
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/248:30 pm
GSP
- GUA
2 stops39h 40m
Multiple Airlines
Deal found 5/19![Multiple Airlines logo]()
$271
This Expedia deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:45 am
CLT
- GUA
1 stop29h 16m
Frontier
Deal found 5/18![Frontier logo]()
$276
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/314:24 pm
CLT
- GUA
2 stops30h 25m
Volaris
Deal found 5/20![Volaris logo]()
$280
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/32:43 pm
CLT
- GUA
2 stops31h 06m
Volaris
Deal found 5/20![Volaris logo]()
$282
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/135:25 pm
CLT
- GUA
2 stops24h 14m
Multiple Airlines
Deal found 5/20![Multiple Airlines logo]()
$295
Find flight deals from South Carolina to Guatemala
Keep the following information in mind while searching for South Carolina to Guatemala flight deals. Data was last updated May 21, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $289 (KAYAK) |
One-way from | $158 (SmartFares) |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Guatemala that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 21, 2026.
Use the filters below to find and compare flights from South Carolina to Guatemala that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlestonGuatemala City
CHS - GUA
CHSGUA
Charleston
Tue 11/3
7:59 pm-10:37 am
1 stop15h 38m
Guatemala City La Aurora
Tue 3/2
7:00 am-10:20 pm
2 stops14h 20m
$455
CharlotteGuatemala City
CLT - GUA
CLTGUA
Charlotte Douglas
Sat 8/29
6:50 am-10:28 am
1 stop5h 38m
Guatemala City La Aurora
Tue 9/1
11:33 am-11:00 pm
1 stop9h 27m
$484
CharlestonGuatemala City
CHS - GUA
CHSGUA
Charleston
Tue 11/3
3:16 pm-10:43 pm
1 stop8h 27m
Guatemala City La Aurora
Mon 11/9
3:52 pm-8:41 am
1 stop15h 49m
$521
CharlestonGuatemala City
CHS - GUA
CHSGUA
Charleston
Sun 9/13
8:43 pm-11:00 am
2 stops16h 17m
Guatemala City La Aurora
Fri 9/18
7:15 am-10:20 am
1 stop25h 05m
$535
CharlotteGuatemala City
CLT - GUA
CLTGUA
Charlotte Douglas
Thu 10/29
10:23 am-11:11 pm
2 stops14h 48m
Guatemala City La Aurora
Wed 11/11
6:24 am-9:44 am
3 stops26h 20m
$543
SavannahGuatemala City
SAV - GUA
SAVGUA
Savannah/Hilton Head
Mon 8/10
11:30 am-7:00 pm
1 stop9h 30m
Guatemala City La Aurora
Mon 8/24
5:25 am-7:35 pm
2 stops12h 10m
$578
CharlestonGuatemala City
CHS - GUA
CHSGUA
Charleston
Thu 7/23
8:13 pm-9:12 am
1 stop14h 59m
Guatemala City La Aurora
Mon 7/27
2:20 pm-10:22 am
1 stop18h 02m
$581
CharlotteGuatemala City
CLT - GUA
CLTGUA
Charlotte Douglas
Tue 11/10
7:47 pm-11:51 am
2 stops17h 04m
Guatemala City La Aurora
Mon 11/30
6:24 am-9:44 am
3 stops26h 20m
$599
AugustaGuatemala City
AGS - GUA
AGSGUA
Augusta Bush Field
Sat 10/10
7:00 am-12:50 pm
1 stop7h 50m
Guatemala City La Aurora
Mon 10/26
1:05 pm-9:38 pm
1 stop6h 33m
$630
AugustaGuatemala City
AGS - GUA
AGSGUA
Augusta Bush Field
Thu 8/27
5:41 am-11:31 am
1 stop7h 50m
Guatemala City La Aurora
Tue 9/1
12:53 pm-11:56 pm
1 stop9h 03m
$633
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from South Carolina to Guatemala
Have a flexible travel schedule? Discover the best time to fly to Guatemala from South Carolina with our price prediction graph.
CLT-GUA
CHS-GUA
GSP-GUA
MYR-GUA
CAE-GUA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Guatemala
USSC-GT0
CLT-GUA
CHS-GUA
GSP-GUA
MYR-GUA
What is the cheapest month to book a flight from South Carolina to Guatemala?
Currently, April is the cheapest month in which you can book a flight from South Carolina to Guatemala (average of $102). Flying from South Carolina to Guatemala in December is currently the most expensive (average of $558). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Guatemala. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Top destinations
Alternative routes for South Carolina to Guatemala
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Guatemala by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Carolina to Guatemala by cabin class
Find flights from South Carolina to Guatemala, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South Carolina and Guatemala flights
Browse other South Carolina and Guatemala flight options. Last updated on May 21, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Guatemala
Find the right flight back to South Carolina after your stay in Guatemala
South Carolina to Guatemala flights
Consider these flights traveling from South Carolina to Guatemala.
Top 3 airlines flying from South Carolina to Guatemala
Discover the top 3 airlines that operate flights from South Carolina to Guatemala. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$211 | Average$606 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$402 | Average$779 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$410 | Average$582 | FlexibilityNo cancel fee | On-time71% |