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Guatemala City

$110+ Cheap flights from South Carolina to Guatemala City (GUA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/28. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — GUA
Dec 6 — Dec 131
Sat 12/6
Sat 12/13
1 adult, Economy
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Find flight deals from South Carolina to Guatemala City

Cheapest flights from South Carolina to Guatemala City
Explore the most affordable flight options available from South Carolina to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2025.

This Mytrip deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/35:59 pmCLT - GUA
2 stops21h 06mSpirit Airlines
Wed 12/101:39 pmGUA - CLT
1 stop9h 20mSpirit Airlines
Deal found 11/5$266
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1410:42 pmCLT - GUA
1 stop15h 40mMultiple Airlines
Fri 12/121:39 pmGUA - CLT
1 stop9h 20mMultiple Airlines
Deal found 11/4$268
This CheapOair deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/287:30 amCLT - GUA
1 stop6h 03mSpirit Airlines
Fri 12/51:39 pmGUA - CLT
1 stop9h 20mSpirit Airlines
Deal found 11/5$273
This Cheapflightsfares deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/27:30 amCLT - GUA
1 stop6h 03mSpirit Airlines
Tue 12/91:39 pmGUA - CLT
1 stop9h 20mSpirit Airlines
Deal found 11/4$275
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/33:56 pmCLT - GUA
1 stop20h 27mSpirit Airlines
Tue 12/91:39 pmGUA - CLT
1 stop9h 20mSpirit Airlines
Deal found 11/5$282
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/210:45 amCLT - GUA
1 stop25h 34mMultiple Airlines
Tue 12/91:39 pmGUA - CLT
1 stop9h 20mMultiple Airlines
Deal found 11/4$284
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2810:13 amCLT - GUA
1 stop23h 47mMultiple Airlines
Fri 12/51:39 pmGUA - CLT
1 stop9h 20mMultiple Airlines
Deal found 11/4$285
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/133:05 pmCAE - GUA
2 stops23h 45mMultiple Airlines
Wed 12/31:38 pmGUA - CAE
1 stop26h 55mMultiple Airlines
Deal found 11/4$288
This Trip.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/249:34 pmCLT - GUA
1 stop14h 51mMultiple Airlines
Wed 12/3110:53 amGUA - CLT
1 stop8h 16mMultiple Airlines
Deal found 11/4$290
This Cheapflightsfares deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/168:59 pmCLT - GUA
1 stop16h 27mSpirit Airlines
Sat 11/221:38 pmGUA - CLT
1 stop8h 54mSpirit Airlines
Deal found 11/3$294
This KAYAK deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/23:56 pmCLT - GUA
1 stop20h 23mSpirit Airlines
Wed 12/241:39 pmGUA - CLT
1 stop8h 50mSpirit Airlines
Deal found 11/5$295
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2810:13 amCLT - GUA
1 stop23h 47mMultiple Airlines
Mon 12/12:55 pmGUA - CLT
1 stop22h 11mMultiple Airlines
Deal found 11/3$297

Cheap flight deals from South Carolina to Guatemala City

Keep the following information in mind while searching for South Carolina to Guatemala City flight deals. Data was last updated November 6, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$252
(Cheapflightsfares)

One-way from

$110
(Cheapflightsfares)

Popular in

December

Cheapest in

August

Average price

$354
Provider with most accurate pricing for Myrtle Beach Intl-Guatemala City La Aurora flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Guatemala City La Aurora flights.
Search Deals
From South Carolina to Guatemala City La Aurora
Search Deals
One-way flight from South Carolina to Guatemala City La Aurora
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($44 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($40 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Guatemala City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from South Carolina to Guatemala City that are best for you.

Fly from

South Carolina

Fly to

Guatemala City

Route

Depart

Return

Price

CharlestonGuatemala City

CHS - GUA

CHSGUA

Charleston

Thu 1/1

10:18 pm-12:34 pm

1 stop15h 16m

Guatemala City La Aurora

Sat 1/10

12:11 pm-8:33 am

1 stop19h 22m

$370

CharlestonGuatemala City

CHS - GUA

CHSGUA

Charleston

Sat 1/31

2:58 pm-9:25 pm

1 stop7h 27m

Guatemala City La Aurora

Tue 2/10

1:28 pm-9:57 pm

1 stop7h 29m

$380

ColumbiaGuatemala City

CAE - GUA

CAEGUA

Columbia Metropolitan

Tue 12/23

9:08 am-2:03 pm

2 stops29h 55m

Guatemala City La Aurora

Mon 12/29

1:39 pm-1:47 pm

1 stop23h 08m

$384

ColumbiaGuatemala City

CAE - GUA

CAEGUA

Columbia Metropolitan

Tue 12/23

9:08 am-11:25 am

2 stops27h 17m

Guatemala City La Aurora

Fri 12/26

1:39 pm-8:16 am

1 stop17h 37m

$425

GreenvilleGuatemala City

GSP - GUA

GSPGUA

Greenville

Thu 12/4

5:17 pm-12:24 pm

2 stops20h 07m

Guatemala City La Aurora

Sun 12/14

1:39 pm-2:10 pm

1 stop23h 31m

$429

CharlotteGuatemala City

CLT - GUA

CLTGUA

Charlotte Douglas

Sat 12/13

8:55 pm-1:23 pm

2 stops17h 28m

Guatemala City La Aurora

Sun 12/21

12:20 pm-11:29 pm

2 stops10h 09m

$438

CharlestonGuatemala City

CHS - GUA

CHSGUA

Charleston

Tue 3/24

5:51 am-1:10 pm

1 stop9h 19m

Guatemala City La Aurora

Wed 3/25

3:15 pm-11:20 pm

1 stop6h 05m

$476

CharlotteGuatemala City

CLT - GUA

CLTGUA

Charlotte Douglas

Sat 12/6

12:59 pm-1:23 pm

3 stops25h 24m

Guatemala City La Aurora

Sun 12/14

12:20 pm-12:04 pm

3 stops22h 44m

$478

CharlestonGuatemala City

CHS - GUA

CHSGUA

Charleston

Wed 12/10

2:43 pm-10:44 am

1 stop21h 01m

Guatemala City La Aurora

Mon 12/15

2:22 pm-8:37 am

1 stop17h 15m

$519

CharlotteGuatemala City

CLT - GUA

CLTGUA

Charlotte Douglas

Sat 11/22

5:59 pm-11:19 am

2 stops18h 20m

Guatemala City La Aurora

Sun 11/30

2:55 pm-4:50 pm

2 stops24h 55m

$530

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/4

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Guatemala City

Have a flexible travel schedule? Discover the best time to fly to Guatemala City from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Guatemala City

What is the cheapest month to book a flight from South Carolina to Guatemala City?

Currently, May is the cheapest month in which you can book a flight from South Carolina to Guatemala City (average of $159). Flying from South Carolina to Guatemala City in December is currently the most expensive (average of $514). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to GUA?

Find hourly flight availability from South Carolina to Guatemala City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 6, 2025.

It’s typically best to fly out from South Carolina to Guatemala City in the evening. Doing so could potentially save you 44% on the flight price compared to flying in the morning, which is usually more expensive.

What is the cheapest day to fly from South Carolina to Guatemala City?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to Guatemala City. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their South Carolina to Guatemala City flight should consider departing on Monday mornings when fares are most often at their lowest. Friday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Guatemala City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Guatemala City from South Carolina?

    Most people fly into Guatemala City La Aurora (GUA) if they book a flight to Guatemala City from South Carolina. La Aurora is conveniently located just 3.7 mi from Guatemala City’s city center.

  • How long is the flight from South Carolina to Guatemala City?

    United Airlines, Spirit Airlines, and American Airlines can get you from South Carolina to Guatemala City in just under 7h 27m. Your travel time can differ by up to 10h 01m. South Carolina and Guatemala City are separated by a distance of 1425 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from South Carolina to Guatemala City?

    Most travelers choose Charlotte Douglas - Guatemala City La Aurora, Greenville - Guatemala City La Aurora or Columbia Metropolitan - Guatemala City La Aurora when deciding on the best route from South Carolina to Guatemala City.

  • Can I find deals for flights from South Carolina to Guatemala City that include hotel bookings?

    Yes. In addition to deals on South Carolina to Guatemala City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Guatemala City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Guatemala City.

  • Can I find deals for business class flights from South Carolina to Guatemala City?

    Yes. Cheapflights offers flight deals from South Carolina to Guatemala City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Guatemala City?

    Currently, May is the cheapest month in which you can book a flight from South Carolina to Guatemala City (average of $159). Flying from South Carolina to Guatemala City in December is currently the most expensive (average of $514). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Guatemala City?

Book flights to Guatemala City if you plan to visit one of these locations
Antigua
Panajachel

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Alternative routes for South Carolina to Guatemala City

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from South Carolina to Guatemala City

Discover the top 4 airlines that operate flights from South Carolina to Guatemala City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$293Average$357FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$349Average$545FlexibilityNo cancel feeOn-time71%
DeltaCheapest$381Average$708FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$482Average$695FlexibilityNo cancel feeOn-time69%

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