$86+ Cheap flights from South Carolina to Guatemala City (GUA)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/10. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — GUA
May 3 — May 101
Round-trip
1 adult, Economy
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Cheapest flights from South Carolina to Guatemala CityExplore the most affordable flight options available from South Carolina to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 3, 2026.
Explore the most affordable flight options available from South Carolina to Guatemala City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 3, 2026.
This CheapOair deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/179:32 pm
CLT
- GUA
1 stop15h 24m
Spirit Airlines
Mon 4/2011:51 am
GUA
- CLT
1 stop6h 46m
Spirit Airlines
Deal found 4/1![Spirit Airlines logo]()
$260
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/110:55 am
CLT
- GUA
1 stop23h 33m
Multiple Airlines
Tue 4/76:38 pm
GUA
- CLT
1 stop15h 29m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$264
This Expedia deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/29:58 pm
CLT
- GUA
1 stop12h 32m
Multiple Airlines
Tue 4/712:23 pm
GUA
- CLT
1 stop10h 15m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$265
This CheapOair deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/143:55 pm
CLT
- GUA
1 stop21h 01m
Spirit Airlines
Fri 4/1711:51 am
GUA
- CLT
1 stop6h 46m
Spirit Airlines
Deal found 3/31![Spirit Airlines logo]()
$267
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/17:00 am
CLT
- GUA
1 stop27h 28m
Multiple Airlines
Wed 4/811:28 am
GUA
- CLT
1 stop6h 20m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/21:46 pm
CLT
- GUA
1 stop23h 46m
Multiple Airlines
Wed 4/811:28 am
GUA
- CLT
1 stop6h 20m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$271
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/17:00 am
CLT
- GUA
1 stop27h 28m
Multiple Airlines
Fri 4/1011:28 am
GUA
- CLT
1 stop6h 20m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$280
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/21:46 pm
CLT
- GUA
1 stop23h 46m
Multiple Airlines
Fri 4/1011:28 am
GUA
- CLT
1 stop6h 20m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$282
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/811:28 am
MYR
- GUA
1 stop14h 36m
Multiple Airlines
Mon 4/1311:28 am
GUA
- MYR
2 stops28h 05m
Multiple Airlines
Deal found 3/29![Multiple Airlines logo]()
$288
This CheapOair deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/139:00 pm
CLT
- GUA
2 stops15h 33m
Spirit Airlines
Sat 4/2511:51 am
GUA
- CLT
2 stops19h 19m
Spirit Airlines
Deal found 3/29![Spirit Airlines logo]()
$289
This CheapOair deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:28 pm
MYR
- GUA
1 stop7h 36m
Spirit Airlines
Mon 4/1311:28 am
GUA
- MYR
1 stop21h 37m
Spirit Airlines
Deal found 3/29![Spirit Airlines logo]()
$312
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/135:43 pm
GSP
- GUA
1 stop19h 41m
Multiple Airlines
Thu 4/2312:10 pm
GUA
- GSP
1 stop26h 43m
Multiple Airlines
Deal found 3/29![Multiple Airlines logo]()
$325
Best flights from South Carolina to Guatemala CityDiscover carefully curated flight deals from South Carolina to Guatemala City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 3, 2026.
Discover carefully curated flight deals from South Carolina to Guatemala City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 3, 2026.
This Priceline deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/131:12 pm
CLT
- GUA
1 stop27h 30m
Frontier
Thu 6/183:47 pm
GUA
- CLT
1 stop18h 30m
Frontier
Deal found 4/2![Frontier logo]()
$328
This Expedia deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:00 am
MYR
- GUA
1 stop7h 12m
Spirit Airlines
Thu 5/2112:17 pm
GUA
- MYR
1 stop6h 19m
Spirit Airlines
Deal found 3/30![Spirit Airlines logo]()
$336
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/148:07 am
CHS
- GUA
1 stop5h 17m
Multiple Airlines
Sun 4/1912:10 pm
GUA
- CHS
2 stops42h 28m
Multiple Airlines
Deal found 3/29![Multiple Airlines logo]()
$386
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/305:00 am
CHS
- GUA
2 stops15h 43m
American Airlines
Thu 5/71:01 pm
GUA
- CHS
2 stops17h 30m
American Airlines
Deal found 3/31![American Airlines logo]()
$495
This United Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:40 am
CHS
- GUA
1 stop6h 45m
United Airlines
Tue 5/53:45 pm
GUA
- CHS
2 stops18h 32m
United Airlines
Deal found 3/29![United Airlines logo]()
$495
This Delta deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:20 am
CHS
- GUA
1 stop8h 26m
Delta
Sun 4/191:14 pm
GUA
- CHS
1 stop7h 48m
Delta
Deal found 3/31![Delta logo]()
$561
This Copa Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:00 am
CLT
- GUA
2 stops15h 59m
Copa Airlines
Sat 5/161:01 pm
GUA
- CLT
2 stops18h 52m
Copa Airlines
Deal found 3/31![Copa Airlines logo]()
$615
This KAYAK deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:06 pm
MYR
- GUA
2 stops17h 06m
GOL
Sat 7/111:10 pm
GUA
- MYR
2 stops17h 26m
GOL
Deal found 3/30![GOL logo]()
$801
This American Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/288:20 pm
CHS
- GUA
1 stop14h 48m
American Airlines
Sat 5/3012:35 am
GUA
- CHS
1 stop12h 18m
American Airlines
Deal found 3/29![American Airlines logo]()
$496
This oojo deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2910:42 am
SAV
- GUA
2 stops24h 18m
Multiple Airlines
Mon 5/43:40 pm
GUA
- SAV
2 stops16h 12m
Multiple Airlines
Deal found 3/29![Multiple Airlines logo]()
$508
This Mytrip deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:31 pm
MYR
- GUA
2 stops18h 04m
Spirit Airlines
Sat 8/11:28 pm
GUA
- MYR
1 stop5h 57m
Spirit Airlines
Deal found 3/31![Spirit Airlines logo]()
$528
This United Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:00 am
CHS
- GUA
2 stops10h 30m
United Airlines
Sun 4/1911:55 pm
GUA
- CHS
1 stop8h 28m
United Airlines
Deal found 4/2![United Airlines logo]()
$561
This American Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:00 am
CHS
- GUA
1 stop14h 43m
American Airlines
Sun 4/193:14 pm
GUA
- CHS
1 stop17h 20m
American Airlines
Deal found 3/29![American Airlines logo]()
$521
This Kiwi.com deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/210:24 am
MYR
- GUA
2 stops24h 36m
Multiple Airlines
Fri 6/57:10 pm
GUA
- MYR
1 stop12h 36m
Multiple Airlines
Deal found 4/2![Multiple Airlines logo]()
$523
This Mytrip deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1412:04 pm
CHS
- GUA
3 stops24h 52m
Spirit Airlines
Sun 4/1912:10 pm
GUA
- CHS
2 stops20h 58m
Spirit Airlines
Deal found 3/29![Spirit Airlines logo]()
$557
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/145:38 am
CAE
- GUA
1 stop7h 53m
Delta
Thu 5/211:01 pm
GUA
- CAE
1 stop8h 48m
Delta
Deal found 3/30![Delta logo]()
$617
This Copa Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1710:13 am
CLT
- GUA
2 stops14h 57m
Copa Airlines
Sat 4/256:24 am
GUA
- CLT
3 stops25h 29m
Copa Airlines
Deal found 3/29![Copa Airlines logo]()
$630
This United Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/253:25 pm
SAV
- GUA
1 stop8h 15m
United Airlines
Tue 9/86:15 am
GUA
- SAV
1 stop13h 38m
United Airlines
Deal found 4/2![United Airlines logo]()
$575
This Justfly.com deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/237:20 pm
CHS
- GUA
2 stops25h 10m
Multiple Airlines
Sun 5/318:15 pm
GUA
- CHS
2 stops34h 24m
Multiple Airlines
Deal found 4/2![Multiple Airlines logo]()
$527
This Copa Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/287:30 pm
CLT
- GUA
3 stops28h 11m
Copa Airlines
Tue 5/56:24 am
GUA
- CLT
3 stops25h 29m
Copa Airlines
Deal found 4/1![Copa Airlines logo]()
$640
This Delta deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:00 am
MYR
- GUA
1 stop7h 46m
Delta
Tue 5/51:14 pm
GUA
- MYR
1 stop9h 00m
Delta
Deal found 3/31![Delta logo]()
$647
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2010:30 am
CAE
- GUA
2 stops11h 00m
American Airlines
Thu 8/2712:27 pm
GUA
- CAE
2 stops20h 20m
American Airlines
Deal found 3/31![American Airlines logo]()
$591
This Kiwi.com deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/171:45 pm
SAV
- GUA
1 stop24h 50m
Multiple Airlines
Mon 4/277:12 am
GUA
- SAV
2 stops13h 36m
Multiple Airlines
Deal found 4/2![Multiple Airlines logo]()
$548
This CheapOair deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/73:43 pm
MYR
- GUA
2 stops20h 40m
Spirit Airlines
Mon 5/1111:18 am
GUA
- MYR
2 stops19h 56m
Spirit Airlines
Deal found 4/1![Spirit Airlines logo]()
$617
This United Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/510:28 am
MYR
- GUA
2 stops10h 21m
United Airlines
Sat 10/31:50 pm
GUA
- MYR
2 stops18h 47m
United Airlines
Deal found 4/1![United Airlines logo]()
$629
This Copa Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/17:44 pm
CLT
- GUA
3 stops27h 57m
Copa Airlines
Tue 6/97:10 am
GUA
- CLT
2 stops24h 35m
Copa Airlines
Deal found 4/1![Copa Airlines logo]()
$645
This Mytrip deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/139:07 pm
CLT
- GUA
1 stop16h 05m
Multiple Airlines
Thu 6/183:47 pm
GUA
- CLT
3 stops23h 13m
Multiple Airlines
Deal found 4/2![Multiple Airlines logo]()
$553
This Delta deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:35 am
SAV
- GUA
1 stop8h 11m
Delta
Mon 5/111:01 pm
GUA
- SAV
1 stop8h 39m
Delta
Deal found 3/31![Delta logo]()
$684
This American Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/268:28 pm
AGS
- GUA
2 stops16h 32m
American Airlines
Sat 10/312:04 pm
GUA
- AGS
1 stop9h 23m
American Airlines
Deal found 3/29![American Airlines logo]()
$629
This Copa Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2310:13 am
CLT
- GUA
2 stops24h 36m
Copa Airlines
Sun 4/266:24 am
GUA
- CLT
3 stops25h 29m
Copa Airlines
Deal found 3/29![Copa Airlines logo]()
$645
Last-minute flights from South Carolina to Guatemala CityDiscover last-minute flight deals from South Carolina to Guatemala City. Data last updated April 3, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Guatemala City. Data last updated April 3, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/29:58 pm
CLT
- GUA
1 stop12h 32m
Multiple Airlines
Tue 4/712:23 pm
GUA
- CLT
1 stop10h 15m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$265
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/21:46 pm
CLT
- GUA
1 stop23h 46m
Multiple Airlines
Wed 4/811:28 am
GUA
- CLT
1 stop6h 20m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$271
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/21:46 pm
CLT
- GUA
1 stop23h 46m
Multiple Airlines
Fri 4/1011:28 am
GUA
- CLT
1 stop6h 20m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$282
This Frontier deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/59:58 pm
CLT
- GUA
1 stop12h 32m
Frontier
Thu 4/99:43 am
GUA
- CLT
1 stop10h 04m
Frontier
Deal found 3/31![Frontier logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/811:28 am
MYR
- GUA
1 stop14h 36m
Multiple Airlines
Mon 4/1311:28 am
GUA
- MYR
2 stops28h 05m
Multiple Airlines
Deal found 3/29![Multiple Airlines logo]()
$288
This CheapOair deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:28 pm
MYR
- GUA
1 stop7h 36m
Spirit Airlines
Mon 4/1311:28 am
GUA
- MYR
1 stop21h 37m
Spirit Airlines
Deal found 3/29![Spirit Airlines logo]()
$312
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:00 am
CLT
- GUA
1 stop7h 14m
Spirit Airlines
Thu 4/2312:10 pm
GUA
- CLT
1 stop6h 39m
Spirit Airlines
Deal found 3/29![Spirit Airlines logo]()
$294
This CheapOair deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/139:00 pm
CLT
- GUA
2 stops15h 33m
Spirit Airlines
Sat 4/2511:51 am
GUA
- CLT
2 stops19h 19m
Spirit Airlines
Deal found 3/29![Spirit Airlines logo]()
$289
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/135:43 pm
GSP
- GUA
1 stop19h 41m
Multiple Airlines
Thu 4/2312:10 pm
GUA
- GSP
1 stop26h 43m
Multiple Airlines
Deal found 3/29![Multiple Airlines logo]()
$325
This CheapOair deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/143:55 pm
CLT
- GUA
1 stop21h 01m
Spirit Airlines
Fri 4/1711:51 am
GUA
- CLT
1 stop6h 46m
Spirit Airlines
Deal found 3/31![Spirit Airlines logo]()
$267
This CheapOair deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/179:32 pm
CLT
- GUA
1 stop15h 24m
Spirit Airlines
Mon 4/2011:51 am
GUA
- CLT
1 stop6h 46m
Spirit Airlines
Deal found 4/1![Spirit Airlines logo]()
$260
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/19:54 pm
CLT
- GUA
1 stop16h 41m
Spirit Airlines
Sun 5/312:10 pm
GUA
- CLT
1 stop6h 39m
Spirit Airlines
Deal found 3/29![Spirit Airlines logo]()
$295
One-way flights from South Carolina to Guatemala CitySearch for one-way flight options from South Carolina to Guatemala City. Find affordable one-way fares based on user searches. Data last updated April 3, 2026.
Search for one-way flight options from South Carolina to Guatemala City. Find affordable one-way fares based on user searches. Data last updated April 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/106:42 pm
CAE
- GUA
1 stop7h 22m
Multiple Airlines
Deal found 3/29![Multiple Airlines logo]()
$86
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/79:00 pm
CLT
- GUA
1 stop16h 24m
Spirit Airlines
Deal found 3/29![Spirit Airlines logo]()
$90
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/93:59 pm
CAE
- GUA
1 stop21h 33m
Multiple Airlines
Deal found 3/29![Multiple Airlines logo]()
$99
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:00 am
CLT
- GUA
1 stop7h 24m
Spirit Airlines
Deal found 3/29![Spirit Airlines logo]()
$101
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/99:00 pm
CLT
- GUA
1 stop29h 04m
Spirit Airlines
Deal found 3/29![Spirit Airlines logo]()
$102
This Mytrip deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:07 am
CHS
- GUA
1 stop5h 17m
Spirit Airlines
Deal found 3/31![Spirit Airlines logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/109:00 pm
CLT
- GUA
1 stop16h 14m
Spirit Airlines
Deal found 3/29![Spirit Airlines logo]()
$119
This Priceline deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/247:58 pm
CLT
- GUA
1 stop20h 44m
Frontier
Deal found 3/29![Frontier logo]()
$129
This CheapOair deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/276:42 pm
CLT
- GUA
2 stops18h 28m
Spirit Airlines
Deal found 3/30![Spirit Airlines logo]()
$140
This Super.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/139:07 pm
CLT
- GUA
1 stop16h 05m
Spirit Airlines
Deal found 3/31![Spirit Airlines logo]()
$147
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/211:52 am
MYR
- GUA
1 stop25h 13m
Spirit Airlines
Deal found 3/29![Spirit Airlines logo]()
$148
This Trip.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:41 pm
CLT
- GUA
1 stop18h 31m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$149
Find flight deals from South Carolina to Guatemala City
Keep the following information in mind while searching for South Carolina to Guatemala City flight deals. Data was last updated April 3, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $260 (CheapOair) |
One-way from | $86 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Guatemala City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 3, 2026.
Use the filters below to find and compare flights from South Carolina to Guatemala City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlotteGuatemala City
CLT - GUA
CLTGUA
Charlotte Douglas
Sat 6/13
1:12 pm-2:42 pm
1 stop27h 30m
Guatemala City La Aurora
Thu 6/18
3:47 pm-12:17 pm
1 stop18h 30m
$328
Quickest round-trip
Myrtle BeachGuatemala City
MYR - GUA
MYRGUA
Myrtle Beach Intl
Thu 5/14
6:00 am-11:12 am
1 stop7h 12m
Guatemala City La Aurora
Thu 5/21
12:17 pm-8:36 pm
1 stop6h 19m
$336
CharlestonGuatemala City
CHS - GUA
CHSGUA
Charleston
Tue 4/14
8:07 am-11:24 am
1 stop5h 17m
Guatemala City La Aurora
Sun 4/19
12:10 pm-8:38 am
2 stops42h 28m
$386
CharlestonGuatemala City
CHS - GUA
CHSGUA
Charleston
Thu 4/30
5:00 am-6:43 pm
2 stops15h 43m
Guatemala City La Aurora
Thu 5/7
1:01 pm-8:31 am
2 stops17h 30m
$495
CharlestonGuatemala City
CHS - GUA
CHSGUA
Charleston
Tue 4/28
6:40 am-11:25 am
1 stop6h 45m
Guatemala City La Aurora
Tue 5/5
3:45 pm-12:17 pm
2 stops18h 32m
$495
CharlestonGuatemala City
CHS - GUA
CHSGUA
Charleston
Thu 5/28
8:20 pm-9:08 am
1 stop14h 48m
Guatemala City La Aurora
Sat 5/30
12:35 am-2:53 pm
1 stop12h 18m
$496
SavannahGuatemala City
SAV - GUA
SAVGUA
Savannah/Hilton Head
Wed 4/29
10:42 am-9:00 am
2 stops24h 18m
Guatemala City La Aurora
Mon 5/4
3:40 pm-9:52 am
2 stops16h 12m
$508
CharlestonGuatemala City
CHS - GUA
CHSGUA
Charleston
Tue 4/14
6:00 am-6:43 pm
1 stop14h 43m
Guatemala City La Aurora
Sun 4/19
3:14 pm-10:34 am
1 stop17h 20m
$521
Myrtle BeachGuatemala City
MYR - GUA
MYRGUA
Myrtle Beach Intl
Tue 6/2
10:24 am-9:00 am
2 stops24h 36m
Guatemala City La Aurora
Fri 6/5
7:10 pm-9:46 am
1 stop12h 36m
$523
CharlestonGuatemala City
CHS - GUA
CHSGUA
Charleston
Sat 5/23
7:20 pm-6:30 pm
2 stops25h 10m
Guatemala City La Aurora
Sun 5/31
8:15 pm-8:39 am
2 stops34h 24m
$527
Showing 1-10 of 59 resultsSorted by cheapest first
Best time to book a flight from South Carolina to Guatemala City
Have a flexible travel schedule? Discover the best time to fly to Guatemala City from South Carolina with our price prediction graph.
CAE-GUA
CLT-GUA
CHS-GUA
MYR-GUA
GSP-GUA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Guatemala City
USSC-GUA
CAE-GUA
CLT-GUA
CHS-GUA
MYR-GUA
What is the cheapest month to book a flight from South Carolina to Guatemala City?
Currently, May is the cheapest month in which you can book a flight from South Carolina to Guatemala City (average of $191). Flying from South Carolina to Guatemala City in December is currently the most expensive (average of $602). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SC to GUA?
Find hourly flight availability from South Carolina to Guatemala City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 3, 2026.
It’s typically best to fly out from South Carolina to Guatemala City in the evening. Doing so could potentially save you 31% on the flight price compared to flying in the morning, which is usually more expensive.
What is the cheapest day to fly from South Carolina to Guatemala City?
Use this chart to determine the cheapest time to fly round-trip from South Carolina to Guatemala City. Price data was last updated on March 30, 2025.
Travelers seeking maximum savings on their South Carolina to Guatemala City flight should consider departing on Monday mornings when fares are most often at their lowest. Thursday mornings flights should be avoided if possible as fares are typically the most expensive at this time.
How much does it cost to fly round-trip from South Carolina to Guatemala City?
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Guatemala City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Guatemala City?
Book flights to Guatemala City if you plan to visit one of these locationsAntigua
Panajachel
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for South Carolina to Guatemala City
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Complete your trip
Complete your trip to Guatemala City by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Carolina to Guatemala City by cabin class
Find flights from South Carolina to Guatemala City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Guatemala City
Explore flights to Guatemala City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 3, 2026.
South Carolina and Guatemala City flights
Browse other South Carolina and Guatemala City flight options. Last updated on April 3, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
South Carolina to Guatemala City flights
Consider these flights traveling from South Carolina to Guatemala City.
Top 3 airlines flying from South Carolina to Guatemala City
Discover the top 3 airlines that operate flights from South Carolina to Guatemala City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$211 | Average$536 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$400 | Average$545 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$402 | Average$755 | FlexibilityNo cancel fee | On-timeN/A |