For a smooth departure from PTY, use the new Line 2 metro branch to quickly reach the airport from Panama City.

Most accurate provider | eDreams 3 stars |
|---|---|
Most trusted provider | eDreams 3 stars |
Round-trip from | $304 (FlightHub) |
One-way from | $160 (FlightHub) |
Popular in | December |
Cheapest in | May |
Average price | $307 |
Good round-trip deal | $274 or less |
Good one-way deal | $155 or less |
Fly from
Fly to
Route
Depart
Return
Price
Panama CityGuatemala City
PTY - GUA
PTYGUA
Panama City Tocumen Intl
Fri 2/13
9:45 am-5:40 pm
1 stop8h 55m
Guatemala City La Aurora
Wed 2/18
5:10 am-10:30 am
1 stop4h 20m
Panama CityGuatemala City
PTY - GUA
PTYGUA
Panama City Tocumen Intl
Wed 1/7
7:31 am-8:55 am
Nonstop2h 24m
Guatemala City La Aurora
Tue 1/13
4:24 am-7:50 am
Nonstop2h 26m
Panama CityGuatemala City
PTY - GUA
PTYGUA
Panama City Tocumen Intl
Mon 1/19
7:31 am-8:55 am
Nonstop2h 24m
Guatemala City La Aurora
Thu 1/22
2:26 am-5:55 am
Nonstop2h 29m
Panama CityGuatemala City
PTY - GUA
PTYGUA
Panama City Tocumen Intl
Sat 1/24
10:25 am-11:51 am
Nonstop2h 26m
Guatemala City La Aurora
Sat 1/31
6:24 am-11:09 am
1 stop3h 45m
Panama CityGuatemala City
PTY - GUA
PTYGUA
Panama City Tocumen Intl
Sun 1/18
9:45 pm-11:11 pm
Nonstop2h 26m
Guatemala City La Aurora
Thu 1/22
4:27 pm-7:51 pm
Nonstop2h 24m
Panama CityGuatemala City
PTY - GUA
PTYGUA
Panama City Tocumen Intl
Thu 2/19
10:10 am-11:36 am
Nonstop2h 26m
Guatemala City La Aurora
Sun 2/22
4:27 pm-7:51 pm
Nonstop2h 24m
Panama CityGuatemala City
PTY - GUA
PTYGUA
Panama City Tocumen Intl
Sat 2/21
7:31 am-8:55 am
Nonstop2h 24m
Guatemala City La Aurora
Sat 2/21
1:15 pm-4:39 pm
Nonstop2h 24m
Panama CityGuatemala City
PTY - GUA
PTYGUA
Panama City Tocumen Intl
Sat 2/7
6:34 pm-9:40 pm
1 stop4h 06m
Guatemala City La Aurora
Wed 2/11
6:24 am-11:09 am
1 stop3h 45m
Panama CityGuatemala City
PTY - GUA
PTYGUA
Panama City Tocumen Intl
Tue 1/20
10:25 am-11:51 am
Nonstop2h 26m
Guatemala City La Aurora
Fri 1/23
6:24 am-11:09 am
1 stop3h 45m
Panama CityGuatemala City
PTY - GUA
PTYGUA
Panama City Tocumen Intl
Fri 2/13
7:31 am-8:55 am
Nonstop2h 24m
Guatemala City La Aurora
Wed 2/18
10:34 am-2:03 pm
Nonstop2h 29m
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*1 star |
To ensure you get the cheapest price possible for a flight from Panama City to Guatemala City, you should look to book at least 55 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Currently, April is the cheapest month in which you can book a flight from Panama City to Guatemala City (average of $134). Flying from Panama City to Guatemala City in February is currently the most expensive (average of $194). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Unlike in the afternoon, when flights are generally more expensive, you can save up to 16% on flights from Panama City to Guatemala City by exploring options for tickets in the evening.
About 4% of weekly flights between Panama City and Guatemala City have experienced delays in the past year, with the average delay time being 108 minutes.
Historically, flights departing in the morning are less likely to be delayed, whereas flights leaving in the early afternoon tend to experience delays more often.
Tuesday tends to have the lowest number of delays on this route, whereas Sunday has historically faced a higher average of delays compared to other days of the week.
Over the last year, Copa Airlines have had the lowest number of delays on this route, with just 4% of flights being delayed.
Entertainment
Overall
Comfort
Boarding
Crew
Food
Reviews
Juan Pablo,Sep 2025
PTY - VVI
Entertainment
Overall
Comfort
Boarding
Crew
Food
Reviews
Juan Pablo,Sep 2025
PTY - VVI
Entertainment
Overall
Comfort
Boarding
Crew
Food
Reviews
Juan Pablo,Sep 2025
PTY - VVI
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$194 | Average$296 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$194 | Average$249 | FlexibilityNo cancel fee | On-time71% |