For a smooth departure from PTY, use the new Line 2 metro branch to quickly reach the airport from Panama City.

Most accurate provider | eDreams 3 stars |
|---|---|
Most trusted provider | eDreams 3 stars |
Round-trip from | $277 (Mytrip) |
One-way from | $155 (Copa Airlines) |
Popular in | February |
Cheapest in | May |
Average price | $291 |
Good round-trip deal | $312 or less |
Good one-way deal | $196 or less |
Fly from
Fly to
Route
Depart
Return
Price
Panama CityGuatemala City
PTY - GUA
PTYGUA
Panama City Tocumen Intl
Thu 11/13
7:57 am-9:20 am
Nonstop2h 23m
Guatemala City La Aurora
Sat 11/15
4:21 am-7:50 am
Nonstop2h 29m
Panama CityGuatemala City
PTY - GUA
PTYGUA
Panama City Tocumen Intl
Sun 11/16
7:57 am-9:20 am
Nonstop2h 23m
Guatemala City La Aurora
Sat 11/22
5:39 am-10:32 am
1 stop3h 53m
Panama CityGuatemala City
PTY - GUA
PTYGUA
Panama City Tocumen Intl
Fri 12/19
7:31 am-8:56 am
Nonstop2h 25m
Guatemala City La Aurora
Tue 12/23
6:24 am-11:09 am
1 stop3h 45m
Panama CityGuatemala City
PTY - GUA
PTYGUA
Panama City Tocumen Intl
Mon 11/24
7:57 am-9:20 am
Nonstop2h 23m
Guatemala City La Aurora
Sun 12/7
4:28 pm-7:55 pm
Nonstop2h 27m
Panama CityGuatemala City
PTY - GUA
PTYGUA
Panama City Tocumen Intl
Thu 12/11
8:11 am-9:34 am
Nonstop2h 23m
Guatemala City La Aurora
Wed 12/17
4:21 am-7:50 am
Nonstop2h 29m
Panama CityGuatemala City
PTY - GUA
PTYGUA
Panama City Tocumen Intl
Fri 1/16
8:11 am-9:34 am
Nonstop2h 23m
Guatemala City La Aurora
Fri 1/23
1:15 pm-4:39 pm
Nonstop2h 24m
Panama CityGuatemala City
PTY - GUA
PTYGUA
Panama City Tocumen Intl
Fri 12/19
8:11 am-9:34 am
Nonstop2h 23m
Guatemala City La Aurora
Tue 12/23
4:21 am-7:50 am
Nonstop2h 29m
Panama CityGuatemala City
PTY - GUA
PTYGUA
Panama City Tocumen Intl
Sat 1/10
10:25 am-11:51 am
Nonstop2h 26m
Panama CityGuatemala City
PTY - GUA
PTYGUA
Panama City Tocumen Intl
Mon 11/10
2:55 am-5:40 pm
1 stop15h 45m
Panama CityGuatemala City
PTY - GUA
PTYGUA
Panama City Tocumen Intl
Fri 12/12
7:31 am-8:56 am
Nonstop2h 25m
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*1 star |
To ensure you get the cheapest price possible for a flight from Panama City to Guatemala City, you should look to book at least 31 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Currently, April is the cheapest month in which you can book a flight from Panama City to Guatemala City (average of $134). Flying from Panama City to Guatemala City in January is currently the most expensive (average of $197). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Unlike in the afternoon, when flights are generally more expensive, you can save up to 20% on flights from Panama City to Guatemala City by exploring options for tickets in the morning.
About 3% of weekly flights between Panama City and Guatemala City have experienced delays in the past year, with the average delay time being 93 minutes.
Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the early afternoon tend to experience delays more often.
Saturday tends to have the lowest number of delays on this route, whereas Monday has historically faced a higher average of delays compared to other days of the week.
Over the last year, Air France have had the lowest number of delays on this route, with just 3% of flights being delayed.
Crew
Boarding
Food
Comfort
Entertainment
Overall
Reviews
Juan Pablo,Sep 2025
PTY - VVI
Crew
Boarding
Food
Comfort
Entertainment
Overall
Reviews
Juan Pablo,Sep 2025
PTY - VVI
Crew
Boarding
Food
Comfort
Entertainment
Overall
Reviews
Juan Pablo,Sep 2025
PTY - VVI
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$194 | Average$293 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$194 | Average$256 | FlexibilityNo cancel fee | On-time71% |