$133+ Cheap flights from San Diego to Greenville (SAN - GSP)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/6. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — GSP
Mar 15 — Mar 221
1 adult, Economy
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Find cheap flights from San Diego to Greenville with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from San Diego to GreenvilleExplore the most affordable flight options available from San Diego to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 13, 2026.
Explore the most affordable flight options available from San Diego to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 13, 2026.
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/116:20 am
SAN
- GSP
1 stop10h 26m
American Airlines
Wed 3/1811:28 am
GSP
- SAN
1 stop11h 52m
American Airlines
Deal found 2/11![American Airlines logo]()
$355
This United Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/118:50 pm
SAN
- GSP
2 stops10h 11m
United Airlines
Wed 3/186:52 am
GSP
- SAN
1 stop7h 18m
United Airlines
Deal found 2/11![United Airlines logo]()
$372
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/910:35 pm
SAN
- GSP
1 stop9h 21m
American Airlines
Wed 3/1111:28 am
GSP
- SAN
1 stop11h 52m
American Airlines
Deal found 2/10![American Airlines logo]()
$374
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/249:55 pm
SAN
- GSP
1 stop8h 31m
Delta
Tue 3/316:14 pm
GSP
- SAN
1 stop7h 45m
Delta
Deal found 2/9![Delta logo]()
$377
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/2510:35 pm
SAN
- GSP
1 stop9h 21m
American Airlines
Sat 3/284:30 pm
GSP
- SAN
1 stop8h 53m
American Airlines
Deal found 2/9![American Airlines logo]()
$380
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/239:55 pm
SAN
- GSP
1 stop8h 31m
Delta
Tue 3/315:41 pm
GSP
- SAN
1 stop8h 28m
Delta
Deal found 2/9![Delta logo]()
$390
This United Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1210:30 pm
SAN
- GSP
1 stop8h 31m
United Airlines
Thu 3/195:32 pm
GSP
- SAN
1 stop8h 08m
United Airlines
Deal found 2/11![United Airlines logo]()
$393
This Southwest deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/119:40 am
SAN
- GSP
2 stops10h 00m
Southwest
Wed 3/1812:35 pm
GSP
- SAN
2 stops9h 55m
Southwest
Deal found 2/11![Southwest logo]()
$403
This United Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/610:40 pm
SAN
- GSP
1 stop8h 19m
United Airlines
Fri 5/87:00 am
GSP
- SAN
1 stop9h 50m
United Airlines
Deal found 2/11![United Airlines logo]()
$407
This Southwest deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/229:15 am
SAN
- GSP
2 stops9h 25m
Southwest
Fri 4/241:50 pm
GSP
- SAN
1 stop11h 10m
Southwest
Deal found 2/11![Southwest logo]()
$412
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/249:55 pm
SAN
- GSP
1 stop8h 31m
Delta
Sun 3/295:40 am
GSP
- SAN
1 stop7h 13m
Delta
Deal found 2/9![Delta logo]()
$417
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:15 am
SAN
- GSP
1 stop10h 29m
American Airlines
Sun 4/265:20 am
GSP
- SAN
1 stop8h 53m
American Airlines
Deal found 2/10![American Airlines logo]()
$418
Best flights from San Diego to GreenvilleDiscover carefully curated flight deals from San Diego to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 13, 2026.
Discover carefully curated flight deals from San Diego to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 13, 2026.
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/116:20 am
SAN
- GSP
1 stop10h 26m
American Airlines
Wed 3/1811:28 am
GSP
- SAN
1 stop11h 52m
American Airlines
Deal found 2/11![American Airlines logo]()
$355
This Southwest deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/259:40 am
SAN
- GSP
2 stops10h 00m
Southwest
Sat 3/286:00 pm
GSP
- SAN
1 stop8h 00m
Southwest
Deal found 2/9![Southwest logo]()
$390
This United Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1210:30 pm
SAN
- GSP
1 stop8h 31m
United Airlines
Thu 3/195:32 pm
GSP
- SAN
1 stop8h 08m
United Airlines
Deal found 2/11![United Airlines logo]()
$393
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2310:30 pm
SAN
- GSP
1 stop7h 56m
Delta
Mon 3/306:14 pm
GSP
- SAN
1 stop7h 45m
Delta
Deal found 2/9![Delta logo]()
$403
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/91:34 pm
SAN
- GSP
1 stop7h 08m
American Airlines
Wed 3/1111:28 am
GSP
- SAN
1 stop11h 52m
American Airlines
Deal found 2/11![American Airlines logo]()
$374
This United Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/610:40 pm
SAN
- GSP
1 stop8h 19m
United Airlines
Fri 5/87:00 am
GSP
- SAN
1 stop9h 50m
United Airlines
Deal found 2/11![United Airlines logo]()
$407
This Delta deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/610:10 pm
SAN
- GSP
1 stop9h 44m
Delta
Fri 5/88:45 am
GSP
- SAN
1 stop7h 05m
Delta
Deal found 2/12![Delta logo]()
$407
This Southwest deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/610:20 am
SAN
- GSP
2 stops8h 20m
Southwest
Fri 5/86:25 am
GSP
- SAN
2 stops8h 25m
Southwest
Deal found 2/11![Southwest logo]()
$417
This United Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:20 am
SAN
- GSP
1 stop7h 34m
United Airlines
Fri 4/242:50 pm
GSP
- SAN
1 stop8h 56m
United Airlines
Deal found 2/11![United Airlines logo]()
$407
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/249:55 pm
SAN
- GSP
1 stop8h 31m
Delta
Sun 3/295:40 am
GSP
- SAN
1 stop7h 13m
Delta
Deal found 2/9![Delta logo]()
$417
This American Airlines deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:15 am
SAN
- GSP
1 stop10h 29m
American Airlines
Sun 4/265:20 am
GSP
- SAN
1 stop8h 53m
American Airlines
Deal found 2/12![American Airlines logo]()
$417
Last-minute flights from San Diego to GreenvilleDiscover last-minute flight deals from San Diego to Greenville. Data last updated February 13, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to Greenville. Data last updated February 13, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/910:35 pm
SAN
- GSP
1 stop9h 21m
American Airlines
Wed 3/1111:28 am
GSP
- SAN
1 stop11h 52m
American Airlines
Deal found 2/10![American Airlines logo]()
$374
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/116:20 am
SAN
- GSP
1 stop10h 26m
American Airlines
Wed 3/1811:28 am
GSP
- SAN
1 stop11h 52m
American Airlines
Deal found 2/11![American Airlines logo]()
$355
This United Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/118:50 pm
SAN
- GSP
2 stops10h 11m
United Airlines
Wed 3/186:52 am
GSP
- SAN
1 stop7h 18m
United Airlines
Deal found 2/11![United Airlines logo]()
$372
This Southwest deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/119:40 am
SAN
- GSP
2 stops10h 00m
Southwest
Wed 3/1812:35 pm
GSP
- SAN
2 stops9h 55m
Southwest
Deal found 2/11![Southwest logo]()
$403
This United Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1210:30 pm
SAN
- GSP
1 stop8h 31m
United Airlines
Thu 3/195:32 pm
GSP
- SAN
1 stop8h 08m
United Airlines
Deal found 2/11![United Airlines logo]()
$393
This Southwest deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/126:45 am
SAN
- GSP
2 stops13h 00m
Southwest
Thu 3/196:25 pm
GSP
- SAN
1 stop7h 45m
Southwest
Deal found 2/11![Southwest logo]()
$431
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/239:55 pm
SAN
- GSP
1 stop8h 31m
Delta
Tue 3/315:41 pm
GSP
- SAN
1 stop8h 28m
Delta
Deal found 2/9![Delta logo]()
$390
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/239:55 pm
SAN
- GSP
1 stop8h 31m
Delta
Sun 3/295:40 am
GSP
- SAN
1 stop7h 13m
Delta
Deal found 2/9![Delta logo]()
$430
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/249:55 pm
SAN
- GSP
1 stop8h 31m
Delta
Tue 3/316:14 pm
GSP
- SAN
1 stop7h 45m
Delta
Deal found 2/9![Delta logo]()
$377
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/249:55 pm
SAN
- GSP
1 stop8h 31m
Delta
Sun 3/295:40 am
GSP
- SAN
1 stop7h 13m
Delta
Deal found 2/9![Delta logo]()
$417
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/2510:35 pm
SAN
- GSP
1 stop9h 21m
American Airlines
Sat 3/284:30 pm
GSP
- SAN
1 stop8h 53m
American Airlines
Deal found 2/9![American Airlines logo]()
$380
This Southwest deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/259:40 am
SAN
- GSP
2 stops10h 00m
Southwest
Sat 3/286:20 am
GSP
- SAN
2 stops10h 45m
Southwest
Deal found 2/9![Southwest logo]()
$422
One-way flights from San Diego to GreenvilleSearch for one-way flight options from San Diego to Greenville. Find affordable one-way fares based on user searches. Data last updated February 13, 2026.
Search for one-way flight options from San Diego to Greenville. Find affordable one-way fares based on user searches. Data last updated February 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/610:00 am
SAN
- GSP
2 stops54h 48m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$133
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1310:00 am
SAN
- GSP
2 stops19h 43m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:25 am
SAN
- GSP
2 stops34h 23m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$135
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1510:00 am
SAN
- GSP
2 stops20h 48m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$138
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/48:45 am
SAN
- GSP
3 stops28h 06m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$139
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:55 am
SAN
- GSP
2 stops30h 58m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:55 am
SAN
- GSP
2 stops30h 58m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/36:55 am
SAN
- GSP
2 stops30h 58m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$146
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/38:00 am
SAN
- GSP
3 stops51h 08m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$149
Find flight deals from San Diego to Greenville
Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $355 (American Airlines) |
One-way from | $133 (Kiwi.com) |
Popular in | February |
Cheapest in | August |
Average price | $846 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 13, 2026.
Use the filters below to find and compare flights from San Diego to Greenville that are best for you.
Fly from
San Diego
Fly to
Greenville
Route
Depart
Return
Price
San DiegoGreenville
SAN - GSP
SANGSP
San Diego
Wed 3/11
6:20 am-7:46 pm
1 stop10h 26m
Greenville
Wed 3/18
11:28 am-8:20 pm
1 stop11h 52m
$355
San DiegoGreenville
SAN - GSP
SANGSP
San Diego
Mon 3/9
1:34 pm-11:42 pm
1 stop7h 08m
Greenville
Wed 3/11
11:28 am-8:20 pm
1 stop11h 52m
$374
San DiegoGreenville
SAN - GSP
SANGSP
San Diego
Wed 3/25
9:40 am-10:40 pm
2 stops10h 00m
Greenville
Sat 3/28
6:00 pm-11:00 pm
1 stop8h 00m
$390
San DiegoGreenville
SAN - GSP
SANGSP
San Diego
Thu 3/12
10:30 pm-10:01 am
1 stop8h 31m
Greenville
Thu 3/19
5:32 pm-10:40 pm
1 stop8h 08m
$393
San DiegoGreenville
SAN - GSP
SANGSP
San Diego
Mon 3/23
10:30 pm-9:26 am
1 stop7h 56m
Greenville
Mon 3/30
6:14 pm-10:59 pm
1 stop7h 45m
$403
San DiegoGreenville
SAN - GSP
SANGSP
San Diego
Wed 5/6
10:40 pm-9:59 am
1 stop8h 19m
Greenville
Fri 5/8
7:00 am-1:50 pm
1 stop9h 50m
$407
San DiegoGreenville
SAN - GSP
SANGSP
San Diego
Wed 5/6
10:10 pm-10:54 am
1 stop9h 44m
Greenville
Fri 5/8
8:45 am-12:50 pm
1 stop7h 05m
$407
San DiegoGreenville
SAN - GSP
SANGSP
San Diego
Wed 4/22
6:20 am-4:54 pm
1 stop7h 34m
Greenville
Fri 4/24
2:50 pm-8:46 pm
1 stop8h 56m
$407
San DiegoGreenville
SAN - GSP
SANGSP
San Diego
Wed 5/6
10:20 am-9:40 pm
2 stops8h 20m
Greenville
Fri 5/8
6:25 am-11:50 am
2 stops8h 25m
$417
San DiegoGreenville
SAN - GSP
SANGSP
San Diego
Tue 3/24
9:55 pm-9:26 am
1 stop8h 31m
Greenville
Sun 3/29
5:40 am-9:53 am
1 stop7h 13m
$417
Showing 1-10 of 20 results
Compare providers for flights from San Diego to Greenville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Diego to Greenville in February.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Diego-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Diego-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Diego-Greenville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Diego-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Diego-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Diego to Greenville
Have a flexible travel schedule? Discover the best time to fly to Greenville from San Diego with our price prediction graph.
SAN-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Greenville
Reviews of airlines servicing Greenville
Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated February 13, 2026.
Read through reviews of airlines operating flights from San Diego to Greenville, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Crew
8.5
Overall
7.9
Comfort
7.9
Entertainment
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Boarding
8.1
Crew
8.5
Overall
7.9
Comfort
7.9
Entertainment
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Boarding
8.1
Crew
8.5
Overall
7.9
Comfort
7.9
Entertainment
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Boarding
8.1
Crew
8.5
Overall
7.9
Comfort
7.9
Entertainment
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Related info for your journey
Find useful and relevant information for your journey from San Diego to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Greenville?
Book flights to Greenville if you plan to visit one of these locationsSimpsonville
Duncan
Greer
Seneca
Anderson
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Other flights to Greenville
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Top 3 airlines flying from San Diego to Greenville
Discover the top 3 airlines that operate flights from San Diego to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$286 | Average$409 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$306 | Average$518 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$312 | Average$502 | FlexibilityNo cancel fee | On-timeN/A |