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$368+ Cheap flights from Rochester, MN to Greenville (RST - GSP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/22. Fares are subject to change and may not be available on all flights or dates of travel.
RST — GSP
Feb 26 — Mar 51
Thu 2/26
Thu 3/5
1 adult, Economy
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Cheap flight deals from Rochester to Greenville

Cheapest flights from Rochester to Greenville
Explore the most affordable flight options available from Rochester to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 27, 2026.

This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:33 pm
RST
-
GSP
1 stop4h 25m
American Airlines
Sat 4/2511:31 am
GSP
-
RST
1 stop7h 31m
American Airlines
Deal found 1/27$368
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/256:37 pm
RST
-
GSP
1 stop4h 05m
American Airlines
Sat 2/287:29 am
GSP
-
RST
1 stop4h 33m
American Airlines
Deal found 1/27$379
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/186:37 pm
RST
-
GSP
1 stop4h 05m
American Airlines
Sat 2/217:29 am
GSP
-
RST
1 stop4h 33m
American Airlines
Deal found 1/26$390
This Delta deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/411:50 am
RST
-
GSP
2 stops9h 34m
Delta
Thu 2/126:49 am
GSP
-
RST
2 stops10h 03m
Delta
Deal found 1/25$450
This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/411:36 am
RST
-
GSP
1 stop4h 06m
American Airlines
Wed 2/117:50 am
GSP
-
RST
1 stop4h 16m
American Airlines
Deal found 1/25$470
This United Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/1911:07 am
RST
-
GSP
1 stop4h 53m
United Airlines
Sun 6/216:30 am
GSP
-
RST
1 stop5h 02m
United Airlines
Deal found 1/25$486
This Delta deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/14:39 pm
RST
-
GSP
2 stops6h 11m
Delta
Tue 2/105:40 am
GSP
-
RST
2 stops6h 25m
Delta
Deal found 1/25$503

Find flight deals from Rochester to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Rochester (RST) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 27, 2026.

Round-trip from

$368
(American Airlines)
From Rochester to Greenville
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Rochester to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
Use the filters below to find and compare flights from Rochester to Greenville that are best for you.

Fly from

Rochester

Fly to

Greenville

Route

Depart

Return

Price

RochesterGreenville

RST - GSP

RSTGSP

Rochester

Wed 4/22

6:33 pm-11:58 pm

1 stop4h 25m

Greenville

Sat 4/25

11:31 am-6:02 pm

1 stop7h 31m

$368

RochesterGreenville

RST - GSP

RSTGSP

Rochester

Wed 4/22

4:45 pm-11:56 pm

2 stops6h 11m

Greenville

Sat 4/25

5:40 am-10:52 am

2 stops6h 12m

$379

RochesterGreenville

RST - GSP

RSTGSP

Rochester

Wed 2/25

6:37 pm-11:42 pm

1 stop4h 05m

Greenville

Sat 2/28

7:29 am-11:02 am

1 stop4h 33m

$379

RochesterGreenville

RST - GSP

RSTGSP

Rochester

Wed 2/18

6:37 pm-11:42 pm

1 stop4h 05m

Greenville

Sat 2/21

7:29 am-11:02 am

1 stop4h 33m

$390

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Best time to book a flight from Rochester to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Rochester with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Rochester to Greenville

What is the cheapest month to book a flight from Rochester, Minnesota to Greenville?

Currently, June is the cheapest month in which you can book a flight from Rochester, Minnesota to Greenville (average of $49). Flying from Rochester, Minnesota to Greenville in December is currently the most expensive (average of $255). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated January 27, 2026.
Read reviews from past customers who have flown American Airlines from Rochester to Greenville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,197 reviews

Entertainment

6.9

Crew

8.0

Food

6.4

Overall

7.2

Comfort

7.2

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
American Airlines
7.2
Good
11,197 reviews
American Airlines
7.2
Good
11,197 reviews

Entertainment

6.9

Crew

8.0

Food

6.4

Overall

7.2

Comfort

7.2

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from Rochester to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Rochester, Minnesota to Greenville?

    Airlines like American Airlines and Delta fly from Rochester, Minnesota to Greenville in about 4h 25m. The time it takes to get you to your destination can typically vary by up to 1h 46m. Rochester, Minnesota and Greenville are separated by a distance of 828 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Rochester to Greenville that include hotel bookings?

    Yes. In addition to deals on Rochester to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Rochester to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Rochester to Greenville.

  • Can I find deals for business class flights from Rochester to Greenville?

    Yes. Cheapflights offers flight deals from Rochester to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Rochester, Minnesota to Greenville?

    Currently, June is the cheapest month in which you can book a flight from Rochester, Minnesota to Greenville (average of $49). Flying from Rochester, Minnesota to Greenville in December is currently the most expensive (average of $255). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Greer
Seneca
Anderson

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Top airline flying from Rochester to Greenville

Discover the top airline that operate flights from Rochester to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$288Average$439FlexibilityNo cancel feeOn-time71%

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