HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Greenville

$143+ Cheap flights from Rochester, MN to Greenville (RST - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/7. Fares are subject to change and may not be available on all flights or dates of travel.
RST — GSP
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Rochester to Greenville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Rochester to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Rochester (RST) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$286
(American Airlines)

One-way from

$143
(American Airlines)
From Rochester to Greenville
Search Deals
One-way flight from Rochester to Greenville
Search Deals

Find flight deals from Rochester to Greenville

Cheapest flights from Rochester to Greenville
Explore the most affordable flight options available from Rochester to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/712:46 pmRST - GSP
1 stop5h 48mAmerican Airlines
Sat 10/118:04 pmGSP - RST
1 stop4h 34mAmerican Airlines
Deal found 9/10$286
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1512:41 pmRST - GSP
1 stop6h 03mAmerican Airlines
Fri 12/198:01 pmGSP - RST
1 stop4h 44mAmerican Airlines
Deal found 9/11$571
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/266:00 amRST - GSP
1 stop3h 56mAmerican Airlines
Tue 9/3010:50 amGSP - RST
2 stops11h 09mAmerican Airlines
Deal found 9/11$572
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/154:20 pmRST - GSP
2 stops6h 36mDelta
Fri 12/197:27 amGSP - RST
2 stops9h 01mDelta
Deal found 9/11$728
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2611:25 amRST - GSP
2 stops10h 02mDelta
Tue 9/305:30 amGSP - RST
2 stops6h 15mDelta
Deal found 9/11$743

Cheapflights Fare Finder

 
Customize your flight search to find flights from Rochester to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Rochester to Greenville that are best for you.

Fly from

Rochester

Fly to

Greenville

Route

Depart

Return

Price

RochesterGreenville

RST - GSP

RSTGSP

Rochester

Tue 10/7

12:46 pm-7:34 pm

1 stop5h 48m

Greenville

Sat 10/11

8:04 pm-11:38 pm

1 stop4h 34m

$286

RochesterGreenville

RST - GSP

RSTGSP

Rochester

Fri 9/26

6:00 am-10:56 am

1 stop3h 56m

Greenville

Tue 9/30

10:50 am-8:59 pm

2 stops11h 09m

$572

RochesterGreenville

RST - GSP

RSTGSP

Rochester

Mon 12/15

6:13 am-7:09 pm

2 stops11h 56m

Greenville

Fri 12/19

8:01 pm-11:45 pm

1 stop4h 44m

$577

RochesterGreenville

RST - GSP

RSTGSP

Rochester

Mon 12/15

4:20 pm-11:56 pm

2 stops6h 36m

Greenville

Fri 12/19

7:27 am-3:28 pm

2 stops9h 01m

$728

RochesterGreenville

RST - GSP

RSTGSP

Rochester

Fri 9/26

11:25 am-10:27 pm

2 stops10h 02m

Greenville

Tue 9/30

5:30 am-10:45 am

2 stops6h 15m

$743

RochesterGreenville

RST - GSP

RSTGSP

Rochester

Tue 10/7

12:46 pm-7:34 pm

1 stop5h 48m

$143

RochesterGreenville

RST - GSP

RSTGSP

Rochester

Mon 9/29

11:49 am-7:53 pm

1 stop7h 04m

$258

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Best time to book a flight from Rochester to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Rochester with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Rochester to Greenville

What is the cheapest month to book a flight from Rochester, Minnesota to Greenville?

Currently, August is the cheapest month in which you can book a flight from Rochester, Minnesota to Greenville (average of $322). Flying from Rochester, Minnesota to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Rochester to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Rochester, Minnesota to Greenville?

    Airlines like American Airlines fly from Rochester, Minnesota to Greenville in about 5h 48m. The time it takes to get you to your destination can typically vary by up to . Rochester, Minnesota and Greenville are separated by a distance of 828 mi.

  • Can I find deals for flights from Rochester to Greenville that include hotel bookings?

    Yes. In addition to deals on Rochester to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Rochester to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Rochester to Greenville.

  • Can I find deals for business class flights from Rochester to Greenville?

    Yes. Cheapflights offers flight deals from Rochester to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Rochester, Minnesota to Greenville?

    Currently, August is the cheapest month in which you can book a flight from Rochester, Minnesota to Greenville (average of $322). Flying from Rochester, Minnesota to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Seneca
Anderson

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Rochester to Greenville

See prices for flight routes from nearby airports that may be better suited for you.
Minneapolis to Charlotte flights
Minneapolis to Charleston flights
Minneapolis to Savannah flights
Minneapolis to Myrtle Beach flights
Minneapolis to Greenville flights
Minneapolis to Columbia flights
Minneapolis to Augusta flights
Sioux Falls to Charleston flights
Fargo to Charlotte flights
Sioux Falls to Savannah flights
Fargo to Greenville flights
Minneapolis to Hilton Head Island flights
Fargo to Charleston flights
Sioux Falls to Charlotte flights
Sioux Falls to Myrtle Beach flights
Rochester to Savannah flights
Duluth to Charleston flights
Fargo to Myrtle Beach flights
Fargo to Savannah flights
Rochester to Charleston flights
La Crosse to Charlotte flights
Sioux Falls to Columbia flights
Sioux Falls to Augusta flights
Duluth to Charlotte flights
Rochester to Charlotte flights
Fargo to Augusta flights
Minneapolis to Florence flights
La Crosse to Savannah flights
Bemidji to Charleston flights
Sioux Falls to Hilton Head Island flights
La Crosse to Greenville flights
Fargo to Columbia flights
La Crosse to Charleston flights
Rochester to Myrtle Beach flights

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.