$373+ Cheap flights from Rochester, MN (RST) to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/14. Fares are subject to change and may not be available on all flights or dates of travel.
RST — CHS
Nov 24 — Dec 11
Round-trip
1 adult, Economy
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Find cheap flights from Rochester to South Carolina with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Rochester to South Carolina
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Cheapest flights from Rochester to South CarolinaExplore the most affordable flight options available from Rochester to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
Explore the most affordable flight options available from Rochester to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/311:23 am -
2 stops10h 28m
Sat 11/77:20 am -
2 stops9h 22m
Deal found 10/22![Delta logo]()
$535
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/14:20 pm -
1 stop4h 39m
Thu 11/126:42 pm -
1 stop6h 17m
Deal found 10/22![American Airlines logo]()
$574
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/14:20 pm -
1 stop4h 39m
Fri 11/133:35 pm -
2 stops9h 24m
Deal found 10/22![American Airlines logo]()
$580
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/212:34 pm -
2 stops7h 19m
Wed 11/116:53 am -
2 stops9h 57m
Deal found 10/22![American Airlines logo]()
$585
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/412:34 pm -
1 stop4h 32m
Wed 11/1111:39 am -
1 stop5h 11m
Deal found 10/22![American Airlines logo]()
$594
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/412:34 pm -
1 stop4h 32m
Sat 11/71:37 pm -
2 stops11h 22m
Deal found 10/22![American Airlines logo]()
$600
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/311:23 am -
2 stops10h 28m
Fri 11/138:11 am -
2 stops15h 37m
Deal found 10/22![Delta logo]()
$601
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/412:34 pm -
2 stops9h 25m
Thu 11/128:41 am -
2 stops8h 09m
Deal found 10/22![American Airlines logo]()
$605
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/17:02 am -
2 stops13h 56m
Wed 11/113:35 pm -
2 stops9h 24m
Deal found 10/22![American Airlines logo]()
$612
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/244:16 pm -
2 stops6h 22m
Mon 11/3010:32 am -
2 stops13h 16m
Deal found 10/22![Delta logo]()
$623
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/312:34 pm -
1 stop4h 32m
Wed 11/116:42 pm -
1 stop6h 17m
Deal found 10/22![American Airlines logo]()
$625
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/312:34 pm -
1 stop4h 32m
Fri 11/133:35 pm -
2 stops9h 24m
Deal found 10/22![American Airlines logo]()
$631
Best flights from Rochester to South CarolinaDiscover carefully curated flight deals from Rochester to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
Discover carefully curated flight deals from Rochester to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2511:32 am -
1 stop7h 16m
Sun 2/288:18 pm -
1 stop4h 45m
Deal found 10/25![American Airlines logo]()
$506
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/244:16 pm -
2 stops6h 22m
Mon 11/3010:32 am -
2 stops13h 16m
Deal found 10/22![Delta logo]()
$623
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2612:40 pm -
2 stops8h 32m
Mon 11/3010:32 am -
2 stops13h 16m
Deal found 10/22![Delta logo]()
$623
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/244:16 pm -
2 stops6h 22m
Sat 11/285:40 am -
2 stops10h 55m
Deal found 10/22![Delta logo]()
$684
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2612:40 pm -
2 stops6h 21m
Sat 11/285:40 am -
2 stops10h 55m
Deal found 10/22![Delta logo]()
$684
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/512:34 pm -
2 stops9h 13m
Thu 11/127:02 am -
1 stop6h 01m
Deal found 10/23![American Airlines logo]()
$839
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/254:16 pm -
2 stops6h 22m
Sat 11/285:40 am -
2 stops10h 55m
Deal found 10/22![Delta logo]()
$772
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/611:23 am -
2 stops23h 50m
Thu 11/127:42 pm -
2 stops15h 31m
Deal found 10/22![Delta logo]()
$825
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:00 am -
2 stops11h 09m
Thu 11/128:11 am -
2 stops8h 24m
Deal found 10/23![Delta logo]()
$1,048
Last-minute flights from Rochester to South CarolinaDiscover last-minute flight deals from Rochester to South Carolina. Data last updated October 25, 2026 and is based on user searches.
Discover last-minute flight deals from Rochester to South Carolina. Data last updated October 25, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/267:08 am -
2 stops11h 19m
Wed 10/285:00 am -
2 stops8h 32m
Deal found 10/20![American Airlines logo]()
$970
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/14:20 pm -
1 stop4h 39m
Thu 11/126:42 pm -
1 stop6h 17m
Deal found 10/22![American Airlines logo]()
$574
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/14:20 pm -
1 stop4h 39m
Fri 11/133:35 pm -
2 stops9h 24m
Deal found 10/22![American Airlines logo]()
$580
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/17:02 am -
2 stops13h 56m
Tue 11/103:26 pm -
2 stops9h 33m
Deal found 10/22![American Airlines logo]()
$612
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/212:34 pm -
2 stops7h 19m
Wed 11/116:53 am -
2 stops9h 57m
Deal found 10/22![American Airlines logo]()
$585
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/311:23 am -
2 stops10h 28m
Sat 11/77:20 am -
2 stops9h 22m
Deal found 10/22![Delta logo]()
$535
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/311:23 am -
2 stops10h 28m
Fri 11/138:11 am -
2 stops15h 37m
Deal found 10/22![Delta logo]()
$601
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/312:34 pm -
1 stop4h 32m
Wed 11/116:42 pm -
1 stop6h 17m
Deal found 10/22![American Airlines logo]()
$625
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/312:34 pm -
1 stop4h 32m
Fri 11/133:35 pm -
2 stops9h 24m
Deal found 10/22![American Airlines logo]()
$631
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/412:34 pm -
1 stop4h 32m
Wed 11/1111:39 am -
1 stop5h 11m
Deal found 10/22![American Airlines logo]()
$594
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/412:34 pm -
1 stop4h 32m
Sat 11/71:37 pm -
2 stops11h 22m
Deal found 10/22![American Airlines logo]()
$600
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/244:16 pm -
2 stops6h 22m
Mon 11/3010:32 am -
2 stops13h 16m
Deal found 10/22![Delta logo]()
$623
One-way flights from Rochester to South CarolinaSearch for one-way flight options from Rochester to South Carolina. Find affordable one-way fares based on user searches. Data last updated October 25, 2026.
Search for one-way flight options from Rochester to South Carolina. Find affordable one-way fares based on user searches. Data last updated October 25, 2026.
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/146:00 am -
2 stops10h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Delta logo]()
$373
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/144:16 pm -
1 stop6h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![American Airlines logo]()
$453
Find flight deals from Rochester to South Carolina
Keep the following information in mind while searching for Rochester to South Carolina flight deals. Data was last updated October 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $506 (American Airlines) |
One-way from | $373 (Delta) |
Cheapflights Fare Finder
Customize your flight search to find flights from Rochester to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
Use the filters below to find and compare flights from Rochester to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
RochesterColumbia
RST Rochester - CAE Columbia Metropolitan
RSTCAE
Rochester
Mon 12/14
6:00 am-5:14 pm
2 stops10h 14m
Columbia Metropolitan
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$373
Quickest round-trip
RochesterColumbia
RST Rochester - CAE Columbia Metropolitan
RSTCAE
Rochester
Mon 12/14
4:16 pm-11:58 pm
1 stop6h 42m
Columbia Metropolitan
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$453
RochesterMyrtle Beach
RST Rochester - MYR Myrtle Beach Intl
RSTMYR
Rochester
Thu 2/25
11:32 am-7:48 pm
1 stop7h 16m
Myrtle Beach Intl
Sun 2/28
8:18 pm-12:03 am
1 stop4h 45m
$506
RochesterGreenville
RST Rochester - GSP Greenville
RSTGSP
Rochester
Tue 11/24
4:16 pm-11:38 pm
2 stops6h 22m
Greenville
Mon 11/30
10:32 am-10:48 pm
2 stops13h 16m
$623
RochesterGreenville
RST Rochester - GSP Greenville
RSTGSP
Rochester
Thu 11/26
12:40 pm-10:12 pm
2 stops8h 32m
Greenville
Mon 11/30
10:32 am-10:48 pm
2 stops13h 16m
$623
RochesterGreenville
RST Rochester - GSP Greenville
RSTGSP
Rochester
Tue 11/24
4:16 pm-11:38 pm
2 stops6h 22m
Greenville
Sat 11/28
5:40 am-3:35 pm
2 stops10h 55m
$684
RochesterGreenville
RST Rochester - GSP Greenville
RSTGSP
Rochester
Thu 11/26
12:40 pm-8:01 pm
2 stops6h 21m
Greenville
Sat 11/28
5:40 am-3:35 pm
2 stops10h 55m
$684
RochesterGreenville
RST Rochester - GSP Greenville
RSTGSP
Rochester
Wed 11/25
4:16 pm-11:38 pm
2 stops6h 22m
Greenville
Sat 11/28
5:40 am-3:35 pm
2 stops10h 55m
$772
RochesterGreenville
RST Rochester - GSP Greenville
RSTGSP
Rochester
Fri 11/6
11:23 am-12:13 pm
2 stops23h 50m
Greenville
Thu 11/12
7:42 pm-10:13 am
2 stops15h 31m
$825
RochesterGreenville
RST Rochester - GSP Greenville
RSTGSP
Rochester
Thu 11/5
12:34 pm-10:47 pm
2 stops9h 13m
Greenville
Thu 11/12
7:02 am-12:03 pm
1 stop6h 01m
$839
Showing 1-10 of 11 resultsSorted by cheapest first
Best time to book a flight from Rochester to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Rochester with our price prediction graph.
RST-CAE
RST-MYR
RST-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Rochester to South Carolina
RST-USSC
RST-CAE
RST-MYR
RST-GSP
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated October 25, 2026.
Read reviews from past customers who have flown American Airlines from Rochester to South Carolina. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.8
Overall
7.0
Crew
7.9
Boarding
7.4
Food
6.4
Comfort
7.1
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Entertainment
6.8
Overall
7.0
Crew
7.9
Boarding
7.4
Food
6.4
Comfort
7.1
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Related info for your journey
Find useful and relevant information for your journey from Rochester to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Rochester to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Rochester to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Rochester and South Carolina flights
Browse other Rochester and South Carolina flight options. Last updated on October 25, 2026.
Popular flight searches
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Rochester to South Carolina flights
Consider these flights traveling from Rochester to South Carolina.
Top airline flying from Rochester to South Carolina
Discover the top airline that operate flights from Rochester to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$288 | Average$477 | FlexibilityNo cancel fee | On-time71% |