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$211+ Cheap flights from Harrisburg to Greenville (MDT - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/6. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — GSP
Aug 23 — Aug 301
Sat 8/23
Sat 8/30
1 adult, Economy
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Cheap flight deals from Harrisburg to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 18, 2025.

Round-trip from

$229
(American Airlines)

One-way from

$211
(Delta)

Popular in

December

Cheapest in

July

Average price

$268
From Harrisburg to Greenville
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One-way flight from Harrisburg to Greenville
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Highest demand for flights based on searches. 9% potential increase in price ($31 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Harrisburg to Greenville

Cheapest flights from Harrisburg to Greenville
Explore the most affordable flight options available from Harrisburg to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 18, 2025.

This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2711:25 amMDT - GSP
1 stop6h 43mAmerican Airlines
Sat 11/18:50 amGSP - MDT
1 stop4h 31mAmerican Airlines
Deal found 8/17$229
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/203:46 pmMDT - GSP
1 stop5h 56mAmerican Airlines
Sun 11/2311:33 amGSP - MDT
1 stop3h 21mAmerican Airlines
Deal found 8/16$264
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/46:45 amMDT - GSP
1 stop5h 11mUnited Airlines
Sun 9/76:02 amGSP - MDT
1 stop3h 31mUnited Airlines
Deal found 8/18$299
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/256:42 amMDT - GSP
1 stop3h 51mAmerican Airlines
Mon 9/298:05 amGSP - MDT
1 stop4h 31mAmerican Airlines
Deal found 8/17$372
This Delta deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/96:00 amMDT - GSP
1 stop4h 09mDelta
Sun 10/126:35 amGSP - MDT
1 stop4h 24mDelta
Deal found 8/16$389
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/22:24 pmMDT - GSP
1 stop4h 28mUnited Airlines
Fri 9/52:51 pmGSP - MDT
1 stop22h 57mUnited Airlines
Deal found 8/16$393
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/22:24 pmMDT - GSP
1 stop23h 52mUnited Airlines
Sat 9/69:17 amGSP - MDT
1 stop7h 37mUnited Airlines
Deal found 8/17$398
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/256:00 amMDT - GSP
1 stop5h 24mDelta
Sun 9/285:30 amGSP - MDT
1 stop5h 28mDelta
Deal found 8/18$415
This Delta deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2512:33 pmMDT - GSP
1 stop6h 50mDelta
Wed 8/276:30 amGSP - MDT
1 stop4h 24mDelta
Deal found 8/15$424

Cheapflights Fare Finder

 
Customize your flight search to find flights from Harrisburg to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2025.
Use the filters below to find and compare flights from Harrisburg to Greenville that are best for you.

Fly from

Harrisburg

Fly to

Greenville

Route

Depart

Return

Price

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Mon 10/27

11:25 am-6:08 pm

1 stop6h 43m

Greenville

Sat 11/1

8:50 am-1:21 pm

1 stop4h 31m

$229

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Thu 11/20

3:46 pm-9:42 pm

1 stop5h 56m

Greenville

Sun 11/23

11:33 am-2:54 pm

1 stop3h 21m

$264

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Fri 9/5

5:48 pm-10:46 pm

1 stop4h 58m

Greenville

Sun 9/7

6:02 am-9:33 am

1 stop3h 31m

$299

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Thu 9/4

6:45 am-11:56 am

1 stop5h 11m

Greenville

Sun 9/7

6:02 am-9:33 am

1 stop3h 31m

$299

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Thu 9/25

6:42 am-10:33 am

1 stop3h 51m

Greenville

Mon 9/29

8:05 am-12:36 pm

1 stop4h 31m

$372

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Thu 10/9

6:00 am-10:09 am

1 stop4h 09m

Greenville

Sun 10/12

6:35 am-10:59 am

1 stop4h 24m

$389

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Tue 9/2

2:24 pm-6:52 pm

1 stop4h 28m

Greenville

Fri 9/5

2:51 pm-1:48 pm

1 stop22h 57m

$393

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Tue 9/2

2:24 pm-2:16 pm

1 stop23h 52m

Greenville

Sat 9/6

9:17 am-4:54 pm

1 stop7h 37m

$398

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Sat 9/6

6:00 am-11:29 am

1 stop5h 29m

$211

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Fri 9/5

5:48 pm-2:16 pm

2 stops20h 28m

$305

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/16

Showing 1-10 of 11 results
1
2

Best time to book a flight from Harrisburg to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to Greenville

What is the cheapest month to book a flight from Harrisburg to Greenville?

Currently, January is the cheapest month in which you can book a flight from Harrisburg to Greenville (average of $329). Flying from Harrisburg to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDT to GSP?

Find hourly flight availability from Harrisburg to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 18, 2025.

It’s typically best to fly out from Harrisburg to Greenville in the morning. Doing so could potentially save you 36% on the flight price compared to flying at noon, which is usually more expensive.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated August 18, 2025.
Read through reviews of airlines operating flights from Harrisburg to Greenville, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,981 reviews

Overall

8.0

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,981 reviews
Delta
8.0
Very good
7,981 reviews

Overall

8.0

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,925 reviews
Delta
8.0
Very good
7,981 reviews

Overall

8.0

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,981 reviews

Overall

8.0

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Harrisburg to Greenville?

    For as low as $299, American Airlines can have you in Greenville from Harrisburg in 4h 58m. Harrisburg and Greenville are separated by a distance of 472 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Harrisburg to Greenville round-trip?

    Cheapflights users have booked flights from Harrisburg to Greenville round-trip from $228. Other airlines that can offer you cheap pricing are Delta, from $228, and United Airlines, from $233. You may be able to fly from Harrisburg to Greenville for 25% less than the average price by searching for these airlines.

  • Can I find deals for flights from Harrisburg to Greenville that include hotel bookings?

    Yes. In addition to deals on Harrisburg to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to Greenville.

  • Can I find deals for business class flights from Harrisburg to Greenville?

    Yes. Cheapflights offers flight deals from Harrisburg to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to Greenville?

    Currently, January is the cheapest month in which you can book a flight from Harrisburg to Greenville (average of $329). Flying from Harrisburg to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Seneca
Anderson

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Top 3 airlines flying from Harrisburg to Greenville

Discover the top 3 airlines that operate flights from Harrisburg to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$228Average$294FlexibilityNo cancel feeOn-time71%
DeltaCheapest$228Average$298FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$233Average$315FlexibilityNo cancel feeOn-time69%

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