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$150+ Cheap flights from Harrisburg to Greenville (MDT - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/25. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — GSP
Apr 22 — Apr 291
Wed 4/22
Wed 4/29
1 adult, Economy
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Cheap flight deals from Harrisburg to Greenville

Cheapest flights from Harrisburg to Greenville
Explore the most affordable flight options available from Harrisburg to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 23, 2026.

This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/214:19 pm
MDT
-
GSP
1 stop6h 27m
Delta
Tue 4/285:50 pm
GSP
-
MDT
1 stop6h 09m
Delta
Deal found 3/22$299
This American Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/204:59 pm
MDT
-
GSP
1 stop4h 39m
American Airlines
Sat 5/237:32 pm
GSP
-
MDT
1 stop4h 54m
American Airlines
Deal found 3/18$304
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/106:32 pm
MDT
-
GSP
1 stop5h 22m
Delta
Tue 4/146:26 pm
GSP
-
MDT
1 stop4h 37m
Delta
Deal found 3/22$309
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/36:15 am
MDT
-
GSP
1 stop3h 40m
United Airlines
Tue 4/77:42 pm
GSP
-
MDT
1 stop3h 46m
United Airlines
Deal found 3/19$319
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/282:33 pm
MDT
-
GSP
1 stop4h 55m
United Airlines
Sun 3/297:42 pm
GSP
-
MDT
1 stop3h 46m
United Airlines
Deal found 3/19$329
This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:20 am
MDT
-
GSP
1 stop4h 35m
Delta
Mon 5/257:20 am
GSP
-
MDT
1 stop4h 37m
Delta
Deal found 3/18$338
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/207:18 pm
MDT
-
GSP
1 stop19h 19m
Allegiant Air
Fri 5/223:22 pm
GSP
-
MDT
1 stop5h 02m
Allegiant Air
Deal found 3/18$344
This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/244:30 pm
MDT
-
GSP
1 stop4h 11m
American Airlines
Tue 3/315:20 am
GSP
-
MDT
1 stop6h 41m
American Airlines
Deal found 3/22$354
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:30 am
MDT
-
GSP
1 stop7h 40m
United Airlines
Sat 5/96:36 am
GSP
-
MDT
1 stop6h 57m
United Airlines
Deal found 3/21$355
This American Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/610:36 am
MDT
-
GSP
1 stop3h 42m
American Airlines
Sat 6/137:32 pm
GSP
-
MDT
1 stop4h 54m
American Airlines
Deal found 3/21$359
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:15 am
MDT
-
GSP
1 stop3h 40m
United Airlines
Sat 5/237:40 pm
GSP
-
MDT
1 stop3h 50m
United Airlines
Deal found 3/18$363

Find flight deals from Harrisburg to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 23, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$304
(American Airlines)

One-way from

$150
(Kiwi.com)

Popular in

October

Cheapest in

July

Average price

$278
Provider with most accurate pricing for Harrisburg-Greenville flight deals.
Search Deals
Provider most trusted by Cheapflights users for Harrisburg-Greenville flights.
Search Deals
From Harrisburg to Greenville
Search Deals
One-way flight from Harrisburg to Greenville
Search Deals
Highest demand for flights based on searches. 21% potential increase in price ($89 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($19 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Harrisburg to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 23, 2026.
Use the filters below to find and compare flights from Harrisburg to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Tue 4/14

6:15 am-9:55 am

1 stop3h 40m

Greenville

Sat 4/18

10:33 am-1:55 pm

1 stop3h 22m

$304

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Sat 4/18

4:19 pm-10:46 pm

1 stop6h 27m

Greenville

Tue 4/21

6:26 pm-11:03 pm

1 stop4h 37m

$304

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Fri 4/10

6:32 pm-11:54 pm

1 stop5h 22m

Greenville

Tue 4/14

6:26 pm-11:03 pm

1 stop4h 37m

$309

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Wed 5/6

6:30 am-2:10 pm

1 stop7h 40m

Greenville

Sat 5/9

6:36 am-1:33 pm

1 stop6h 57m

$355

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Wed 5/20

6:20 am-10:55 am

1 stop4h 35m

Greenville

Mon 5/25

7:20 am-11:57 am

1 stop4h 37m

$365

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Sat 4/4

6:15 am-9:55 am

1 stop3h 40m

Greenville

Wed 4/8

6:30 am-1:30 pm

1 stop7h 00m

$389

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Tue 4/21

6:15 am-11:54 am

1 stop5h 39m

Greenville

Tue 4/28

2:53 pm-4:51 pm

3 stops25h 58m

$490

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Fri 5/15

5:00 pm-9:38 pm

1 stop4h 38m

Greenville

Mon 5/18

7:42 pm-11:51 pm

1 stop4h 09m

$495
Cheapest one-way

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Thu 6/25

8:50 pm-7:34 am

1 stop10h 44m

$150

HarrisburgGreenville

MDT - GSP

MDTGSP

Harrisburg

Thu 6/25

6:03 pm-7:48 pm

2 stops25h 45m

$211

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/18

Showing 1-10 of 18 resultsSorted by cheapest first
1
2

Compare providers for flights from Harrisburg to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Harrisburg to Greenville in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Harrisburg-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Harrisburg-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Harrisburg-Greenville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Harrisburg-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Harrisburg-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Harrisburg to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to Greenville

What is the cheapest month to book a flight from Harrisburg to Greenville?

Currently, June is the cheapest month in which you can book a flight from Harrisburg to Greenville (average of $68). Flying from Harrisburg to Greenville in April is currently the most expensive (average of $157). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated March 23, 2026.
Read through reviews of airlines operating flights from Harrisburg to Greenville, such as Delta,United Airlines, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,319 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Food

7.2

Entertainment

7.8

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,319 reviews
Delta
7.9
Good
8,319 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Food

7.2

Entertainment

7.8

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,460 reviews
Delta
7.9
Good
8,319 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Food

7.2

Entertainment

7.8

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,489 reviews
Delta
7.9
Good
8,319 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Food

7.2

Entertainment

7.8

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Harrisburg to Greenville?

    For as low as $304, United Airlines can have you in Greenville from Harrisburg in 3h 40m. Harrisburg and Greenville are separated by a distance of 472 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Harrisburg to Greenville round-trip?

    Cheapflights users have booked flights from Harrisburg to Greenville round-trip from $228. Other airlines that can offer you cheap pricing are Delta, from $228, and United Airlines, from $233. You may be able to fly from Harrisburg to Greenville for 29% less than the average price by searching for these airlines.

  • Can I find deals for flights from Harrisburg to Greenville that include hotel bookings?

    Yes. In addition to deals on Harrisburg to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to Greenville.

  • Can I find deals for business class flights from Harrisburg to Greenville?

    Yes. Cheapflights offers flight deals from Harrisburg to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to Greenville?

    Currently, June is the cheapest month in which you can book a flight from Harrisburg to Greenville (average of $68). Flying from Harrisburg to Greenville in April is currently the most expensive (average of $157). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Greer
Simpsonville
Duncan
Seneca
Anderson

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Top 3 airlines flying from Harrisburg to Greenville

Discover the top 3 airlines that operate flights from Harrisburg to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 23, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$228Average$293FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$228Average$294FlexibilityNo cancel feeOn-time71%
DeltaCheapest$228Average$298FlexibilityNo cancel feeOn-timeN/A

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