HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Greenville

$100+ Cheap flights from O'Hare Intl (ORD) to Greenville (GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/17. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — GSP
Aug 3 — Aug 101
Sun 8/3
Sun 8/10
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from O'Hare Intl to Greenville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Chicago O'Hare Intl to Greenville are usually found in June or July, booked 77 days in advance, depart on a Wednesday or Saturday and return on a Friday

Cheap flight deals from O'Hare Intl to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from O'Hare Intl (ORD) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 29, 2025.

Round-trip from

$219
(United Airlines)

One-way from

$100
(Mytrip)

Popular in

December

Cheapest in

June

Average price

$287

Good round-trip deal

$245 or less

Good one-way deal

$258 or less
From Chicago O'Hare Intl to Greenville
Search Deals
One-way flight from Chicago O'Hare Intl to Greenville
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($9 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 0% potential price decrease ($4 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2025
Search Deals
Price to beat on a round-trip flight from Chicago O'Hare Intl to Greenville.
Search Deals
Price to beat on a one-way flight from Chicago O'Hare Intl to Greenville.
Search Deals

Find flight deals from O'Hare Intl to Greenville

Cheapest flights from O'Hare Intl to Greenville
Explore the most affordable flight options available from O'Hare Intl to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/201:50 pmORD - GSP
Nonstop2h 03mUnited Airlines
Sun 8/246:02 amGSP - ORD
1 stop4h 34mUnited Airlines
Deal found 7/27$219
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/177:20 amORD - GSP
1 stop5h 08mDelta
Sun 9/217:05 amGSP - ORD
1 stop4h 14mDelta
Deal found 7/28$222
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2011:45 amORD - GSP
1 stop6h 09mAmerican Airlines
Sun 8/247:37 amGSP - ORD
Nonstop2h 22mAmerican Airlines
Deal found 7/29$236
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/81:50 pmORD - GSP
1 stop6h 10mSouthwest
Tue 9/910:25 amGSP - ORD
2 stops12h 05mSouthwest
Deal found 7/29$302

Cheapflights Fare Finder

 
Customize your flight search to find flights from O'Hare Intl to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Greenville that are best for you.

Fly from

O'Hare Intl

Fly to

Greenville

Route

Depart

Return

Price

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Wed 8/20

1:50 pm-4:53 pm

Nonstop2h 03m

Greenville

Sun 8/24

6:02 am-9:36 am

1 stop4h 34m

$219

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Wed 9/17

7:20 am-1:28 pm

1 stop5h 08m

Greenville

Sun 9/21

7:05 am-10:19 am

1 stop4h 14m

$222

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Wed 8/20

6:03 am-1:39 pm

1 stop6h 36m

Greenville

Mon 8/25

7:46 pm-8:57 pm

Nonstop2h 11m

$236

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Mon 8/25

7:30 am-6:05 pm

2 stops9h 35m

Greenville

Tue 8/26

10:25 am-9:30 pm

2 stops12h 05m

$314

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Sat 9/6

5:17 pm-10:28 am

1 stop16h 11m

Greenville

Mon 9/8

7:26 pm-1:09 pm

2 stops18h 43m

$316

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Wed 9/17

5:17 pm-10:28 am

1 stop16h 11m

$100

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Sat 8/30

6:00 pm-11:33 pm

1 stop4h 33m

$108

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Mon 9/8

1:50 pm-9:00 pm

1 stop6h 10m

$125

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Sat 8/23

7:24 am-6:52 pm

2 stops10h 28m

$200

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Thu 10/2

4:55 pm-7:53 pm

Nonstop1h 58m

$223

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Best time to book a flight from O'Hare Intl to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from O'Hare Intl with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago O'Hare Intl Airport to Greenville

How far ahead should I book a flight from Chicago O'Hare Intl Airport to Greenville?

Use this chart to determine the optimal time to book a round-trip flight from O'Hare Intl to Greenville. Price data was last updated on July 25, 2025.

The price you pay for your flight from Chicago O'Hare Intl Airport to Greenville may vary depending on when you book. For the best chance of a lower fare, look to book 77 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to Greenville?

Currently, January is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to Greenville (average of $329). Flying from Chicago O'Hare Intl Airport to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ORD to GSP?

Find hourly flight availability from O'Hare Intl to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 29, 2025.

One of the essential ways to save on airfare from Chicago O'Hare Intl Airport to Greenville is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 8% on airfare.

What is the cheapest day to fly from Chicago O'Hare Intl Airport to Greenville?

Use this chart to determine the cheapest time to fly round-trip from O'Hare Intl to Greenville. Price data was last updated on July 27, 2025.

Travelers seeking maximum savings on their Chicago O'Hare Intl Airport to Greenville flight should consider departing on Tuesday mornings when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Chicago O'Hare Intl Airport to Greenville

Explore weekly flight availability from O'Hare Intl to Greenville. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated July 29, 2025.

The most flights from ORD to GSP are scheduled on a Wednesday (20 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (1 on average).

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated July 29, 2025.
Read through reviews of airlines operating flights from Chicago O'Hare Intl Airport to Greenville, such as Southwest, Delta, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Boarding

8.1

Overall

8.0

Entertainment

7.5

Food

7.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Southwest
8.0
Very good
4,238 reviews
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Boarding

8.1

Overall

8.0

Entertainment

7.5

Food

7.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Delta
8.0
Very good
7,979 reviews
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Boarding

8.1

Overall

8.0

Entertainment

7.5

Food

7.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
United Airlines
7.4
Good
8,896 reviews
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Boarding

8.1

Overall

8.0

Entertainment

7.5

Food

7.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Boarding

8.1

Overall

8.0

Entertainment

7.5

Food

7.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.

Related info for your journey

Find useful and relevant information for your journey from O'Hare Intl to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Greenville from Chicago O'Hare Intl?

    Located just 10.4 mi from the city center, Greenville is the airport most travelers will use when flying to Greenville from Chicago O'Hare Intl. Booking flights from Chicago O'Hare Intl to Greenville (GSP) should be relatively easy as there are 11 daily inbound flights from Chicago O'Hare Intl from 2 different airlines.

  • What are the cheapest airlines flying from Chicago O'Hare Intl Airport to Greenville round-trip?

    Flying on United Airlines is currently your cheapest option to Greenville, with prices starting at $219. Additional round-trip tickets that might be worth considering are offered by Delta and American Airlines, with the lowest prices starting at $222 and $236, respectively. You may be able to fly from Chicago O'Hare Intl Airport to Greenville for 29% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Chicago O'Hare Intl Airport to Greenville one-way?

    $108 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on Southwest and United Airlines, with prices starting from $125 and $200, respectively.

  • What are the most reliable airlines from Chicago O'Hare Intl Airport to Greenville?

    Before booking your flight to Greenville from Chicago O'Hare Intl Airport, check out the most reliable airlines to get you to your destination on time: GoJet (89%), Republic Airways (80%), Air New Zealand( 77%).

  • What are the cheapest flights from Chicago O'Hare Intl Airport to Greenville?

    While on average a flight from Chicago O'Hare Intl Airport to Greenville is generally $388, our data shows the cheapest flight currently is $209. When looking at the most popular route, (Chicago O'Hare Intl - Greenville), you can expect to pay $195 for that flight.

  • Can I find deals for flights from O'Hare Intl to Greenville that include hotel bookings?

    Yes. In addition to deals on O'Hare Intl to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from O'Hare Intl to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from O'Hare Intl to Greenville.

  • Can I find deals for business class flights from O'Hare Intl to Greenville?

    Yes. Cheapflights offers flight deals from O'Hare Intl to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to Greenville?

    Currently, January is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to Greenville (average of $329). Flying from Chicago O'Hare Intl Airport to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Seneca
Anderson

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 2 airlines flying from O'Hare Intl to Greenville

Discover the top 2 airlines that operate flights from O'Hare Intl to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$202Average$296FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$209Average$365FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.